{"id":98144,"date":"2024-08-17T08:32:10","date_gmt":"2024-08-17T01:32:10","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=98144"},"modified":"2025-07-24T13:23:24","modified_gmt":"2025-07-24T06:23:24","slug":"topflovir-300mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/topflovir-300mg\/","title":{"rendered":"Topflovir 300mg"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Topflovir 300mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Sinh d\u01b0\u1ee3c ph\u1ea9m HERA, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 QL\u0110B-677-18<\/b><\/p>\n

\"Thu\u1ed1c — Ch\u1ec9 \u0111\u1ecbnh c\u1ee7a thu\u1ed1c Topflovir 300mg<\/figcaption><\/figure>\n
Topflovir 300mg l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n
Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n
**Thu\u1ed1c Topflovir 300mg<\/b> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n**
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Tenofovir disoproxil fumarate 300mg<\/span><\/li>\n
T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/span><\/li>\n<\/ul>\n
D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/span><\/p>\n
Tr\u00ecnh b\u00e0y<\/span><\/h3>\n
S\u0110K: VD-25296-16<\/span><\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/span><\/p>\n
Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/span><\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Topflovir 300mg Herabiopharm<\/span><\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/span><\/h3>\n
Tenofovir disoproxil fumarate<\/b> l\u00e0 ti\u1ec1n ch\u1ea5t c\u1ee7a tenofovir, m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf phi\u00ean m\u00e3 ng\u01b0\u1ee3c. Tenofovir disoproxil fumarate \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh tenofovir diphosphate trong t\u1ebf b\u00e0o, c\u1ea1nh tranh v\u1edbi ch\u1ea5t n\u1ec1n t\u1ef1 nhi\u00ean \u0111\u1ec3 ch\u1eb7n qu\u00e1 tr\u00ecnh sao ch\u00e9p c\u1ee7a HIV v\u00e0 HBV. So v\u1edbi Tenofovir disoproxil fumarate, Tenofovir Alafenamide c\u00f3 kh\u1ea3 n\u0103ng x\u00e2m nh\u1eadp v\u00e0o t\u1ebf b\u00e0o hi\u1ec7u qu\u1ea3 h\u01a1n v\u00e0 \u00edt g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean th\u1eadn v\u00e0 x\u01b0\u01a1ng, nh\u1edd \u0111\u00f3 Tenofovir disoproxil fumarate \u0111\u01b0\u1ee3c xem l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb \u01b0u ti\u00ean h\u01a1n cho b\u1ec7nh nh\u00e2n nhi\u1ec5m HIV v\u00e0 HBV m\u1ea1n t\u00ednh.\u00a0\u00a0<\/span><\/p>\n
\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n
Sau khi u\u1ed1ng, Tenofovir disoproxil nhanh ch\u00f3ng \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh d\u1ea1ng ho\u1ea1t ch\u1ea5t Tenofovir v\u00e0 s\u1ef1 c\u00f3 m\u1eb7t c\u1ee7a ch\u1ea5t b\u00e9o khi \u0103n gi\u00fap t\u0103ng c\u01b0\u1eddng sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c. Tenofovir ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i trong c\u01a1 th\u1ec3, ch\u1ee7 y\u1ebfu qua th\u1eadn. Thu\u1ed1c li\u00ean k\u1ebft protein huy\u1ebft t\u01b0\u01a1ng r\u1ea5t th\u1ea5p v\u00e0 \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua th\u1eadn. Tenofovir \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a theo m\u1ed9t con \u0111\u01b0\u1eddng kh\u00e1c, kh\u00f4ng li\u00ean quan \u0111\u1ebfn h\u1ec7 th\u1ed1ng cytochrome P450. N\u1eeda \u0111\u1eddi c\u1ee7a Tenofovir trong c\u01a1 th\u1ec3 l\u00e0 kho\u1ea3ng 17 gi\u1edd.<\/span><\/p>\n
Thu\u1ed1c Topflovir 300mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n
Ch\u1ec9 \u0111\u1ecbnh c\u1ee7a thu\u1ed1c <\/span>**Topflovir 300mg<\/b>:<\/span><\/p>\n**
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Nhi\u1ec5m HIV-1:<\/span>\n
\n
\u1ede ng\u01b0\u1eddi l\u1edbn khi k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng virus kh\u00e1c.<\/span><\/li>\n
\u1ede thanh thi\u1ebfu ni\u00ean t\u1eeb 12-18 tu\u1ed5i kh\u00e1ng ho\u1eb7c kh\u00f4ng dung n\u1ea1p c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb HIV kh\u00e1c.<\/span><\/li>\n<\/ul>\n<\/li>\n
Vi\u00eam gan B m\u1ea1n t\u00ednh\u00a0<\/span>\n
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\u1ede ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh: \u0110\u1ec1 kh\u00e1ng Lamivudine, b\u1ec7nh gan m\u1ea5t b\u00f9, b\u1ec7nh gan c\u00f2n b\u00f9, c\u00f3 d\u1ea5u hi\u1ec7u vi\u00eam ho\u1eb7c x\u01a1 h\u00f3a.<\/span><\/li>\n
\u1ede ng\u01b0\u1eddi l\u1edbn c\u00f3 b\u1ec7nh gan m\u1ea5t b\u00f9.<\/span><\/li>\n
\u1ede thanh thi\u1ebfu ni\u00ean t\u1eeb 12-18 tu\u1ed5i v\u1edbi b\u1ec7nh gan c\u00f2n b\u00f9 v\u00e0 c\u00f3 d\u1ea5u hi\u1ec7u vi\u00eam ho\u1eb7c x\u01a1 h\u00f3a.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n
Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Topflovir 300mg<\/span><\/h2>\n
C\u00e1ch d\u00f9ng: U\u1ed1ng 1 l\u1ea7n\/ng\u00e0y, c\u00f3 th\u1ec3 nghi\u1ec1n n\u00e1t n\u1ebfu kh\u00f3 nu\u1ed1t.<\/span><\/p>\n
Li\u1ec1u d\u00f9ng thu\u1ed1c **Topflovir 300mg Herabiopharm<\/strong>:<\/span><\/p>\n**
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Ng\u01b0\u1eddi l\u1edbn: U\u1ed1ng 1 vi\u00ean\/ng\u00e0y, c\u00f9ng v\u1edbi th\u1ee9c \u0103n.<\/span><\/li>\n
Thi\u1ebfu ni\u00ean t\u1eeb 12 \u0111\u1ebfn d\u01b0\u1edbi 18 tu\u1ed5i: U\u1ed1ng 1 vi\u00ean\/ng\u00e0y (n\u1ebfu c\u00e2n n\u1eb7ng \u2265 35kg).<\/span><\/li>\n
Tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i: Ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7 \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh li\u1ec1u d\u00f9ng<\/span><\/li>\n
Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi gi\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh c\u1ea9n th\u1eadn v\u00e0 ch\u01b0a c\u00f3 khuy\u1ebfn c\u00e1o chung.\u00a0<\/span><\/li>\n
Suy th\u1eadn: C\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u Topflovir 300mg t\u00f9y thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 suy th\u1eadn.<\/span><\/li>\n
Suy gan: Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/span><\/li>\n<\/ul>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Topflovir 300mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Topflovir 300mg cho ng\u01b0\u1eddi b\u1ecb d\u1ecb \u1ee9ng v\u1edbi Tenofovir.<\/span><\/p>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Topflovir 300mg<\/span><\/h2>\n
Th\u1eadn tr\u1ecdng<\/span><\/h3>\n
X\u00e9t nghi\u1ec7m HIV tr\u01b0\u1edbc khi d\u00f9ng cho ng\u01b0\u1eddi nhi\u1ec5m HBV.<\/span><\/p>\n
Tenofovir kh\u00f4ng ng\u0103n ng\u1eeba l\u00e2y truy\u1ec1n HBV.<\/span><\/p>\n
Kh\u00f4ng d\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c ch\u1ee9a Adefovir, Tenofovir, Didanosin.<\/span><\/p>\n
Theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn th\u01b0\u1eddng xuy\u00ean, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 suy th\u1eadn.<\/span><\/p>\n
Th\u00f4ng b\u00e1o cho ng\u01b0\u1eddi b\u1ec7nh v\u1ec1 nguy c\u01a1 l\u00e2y nhi\u1ec5m.<\/span><\/p>\n
T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/span><\/h3>\n
Ti\u00eau h\u00f3a: Bu\u1ed3n n\u00f4n, kh\u00f3 ti\u00eau. Kho\u1ea3ng 1\/3 b\u1ec7nh nh\u00e2n HIV v\u00e0 1\/4 b\u1ec7nh nh\u00e2n vi\u00eam gan B c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i.<\/span><\/p>\n
Th\u1eadn: Hi\u1ebfm g\u1eb7p suy th\u1eadn, h\u1ed9i ch\u1ee9ng Fanconi c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 x\u01b0\u01a1ng.<\/span><\/p>\n
T\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c: K\u1ebft h\u1ee3p v\u1edbi didanosin: T\u0103ng nguy c\u01a1 vi\u00eam t\u1ee5y v\u00e0 nhi\u1ec5m acid lactic.<\/span><\/p>\n
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/span><\/h3>\n
Nghi\u00ean c\u1ee9u t\u01b0\u01a1ng t\u00e1c c\u1ee7a Topflovir 300mg ch\u1ee7 y\u1ebfu \u1edf ng\u01b0\u1eddi l\u1edbn.<\/span><\/p>\n
\u00cdt t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c qua CYP450.<\/span><\/p>\n
Kh\u00f4ng t\u01b0\u01a1ng t\u00e1c \u0111\u00e1ng k\u1ec3 c\u00f9ng c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1c khi d\u00f9ng chung v\u1edbi Efavirenz, Emtricitabine, Ethinyl oestradiol, Indinavir, Lamivudine, Methadone, Nelfinavir, Norgestimat<\/span><\/p>\n
ribavirin, Rifampicin, Saquinavir, Tacrolimus<\/span><\/p>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/span><\/h3>\n
S\u1eed d\u1ee5ng Topflovir 300mg \u1edf ph\u1ee5 n\u1eef mang thai ch\u1ec9 \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc trong tr\u01b0\u1eddng h\u1ee3p th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 sau khi \u0111\u00e1nh gi\u00e1 k\u1ef9 l\u01b0\u1ee1ng l\u1ee3i \u00edch\/nguy c\u01a1. Tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Topflovir 300mg khi \u0111ang cho con b\u00fa.<\/span><\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n
Trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u Topflovir 300mg, c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd b\u1ec7nh nh\u00e2n v\u00e0 \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 c\u1ea7n thi\u1ebft. Thu\u1ed1c Topflovir 300mg c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf qua th\u1ea9m t\u00e1ch m\u00e1u.<\/span><\/p>\n
Thu\u1ed1c Topflovir 300mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n
Thu\u1ed1c Topflovir 300mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n
Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Topflovir 300mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Topflovir 300mg nh\u01b0:\u00a0\u00a0<\/span><\/p>\n
Thu\u1ed1c <\/span>AgiFovir- F<\/span><\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1ea1i Vi\u1ec7t Nam do C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Agimexpharm, ch\u1ee9a th\u00e0nh ph\u1ea7n 600mg Efavirenz, 300mg Lamivudine, v\u00e0 300mg Tenofovir, ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf enzym phi\u00ean m\u00e3 ng\u01b0\u1ee3c c\u1ee7a HIV-1, ng\u0103n ch\u1eb7n s\u1ef1 sao ch\u00e9p v\u00e0 nh\u00e2n l\u00ean c\u1ee7a virus, v\u00e0 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p thu\u1ed1c kh\u00e1ng retrovirus cho ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh > 18 tu\u1ed5i b\u1ecb nhi\u1ec5m HIV-1.<\/span><\/p>\n
Thu\u1ed1c <\/span>Tenofovir Disoproxil fumarate Tablets 300mg Mylan<\/span><\/a>, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1ea1i M\u1ef9 b\u1edfi APC Pharmaceuticals & Chemical Limited, ch\u1ee9a th\u00e0nh ph\u1ea7n Tenofovir 300mg, ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf virus HIV v\u00e0 vi\u00eam gan B, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb HIV \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh v\u00e0 vi\u00eam gan B m\u1ea1n t\u00ednh, v\u1edbi gi\u00e1 b\u00e1n ch\u01b0a x\u00e1c \u0111\u1ecbnh, v\u00e0 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh hi\u1ec7u qu\u1ea3 cao, \u0111\u1ed9c t\u00ednh th\u1ea5p so v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng virus kh\u00e1c.<\/span><\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n
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Chanie Wassner, Nicole Bradley, Yuman Lee. (Ng\u00e0y 15 th\u00e1ng 4 n\u0103m 2020). <\/span>*A Review and Clinical Understanding of Tenofovir: Tenofovir Disoproxil Fumarate versus Tenofovir Alafenamide<\/span><\/i>. Truy c\u1eadp ng\u00e0y 16 th\u00e1ng 8 n\u0103m 2024, t\u1eeb <\/span>https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7163232\/<\/span><\/a><\/li>\n*
Golasa Samadi Kochaksaraei, Abdel A Shaheen, Cynthia H Seow, Herman W Barkema, Carla S Coffin. (Th\u00e1ng 8 n\u0103m 2022). Tenofovir disoproxil fumarate therapy to prevent hepatitis B virus vertical transmission-A review of maternal and infant outcomes<\/i>. Truy c\u1eadp ng\u00e0y 16 th\u00e1ng 8 n\u0103m 2024, t\u1eeb <\/span>https:\/\/pubmed.ncbi.nlm.nih.gov\/35312156\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
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