{"id":97662,"date":"2024-08-12T21:18:27","date_gmt":"2024-08-12T14:18:27","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=97662"},"modified":"2025-07-24T13:30:39","modified_gmt":"2025-07-24T06:30:39","slug":"savi-direin-50","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/savi-direin-50\/","title":{"rendered":"Savi Direin 50"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/savi-direin-50\/\">Savi Direin 50<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Sa Vi, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-18346-13.<\/strong><\/p>\n<h2>Savi Direin 50 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean <strong>thu\u1ed1c Savi Direin<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: Diacerein 50mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang c\u1ee9ng<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-18346-13<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_97674\" aria-describedby=\"caption-attachment-97674\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/vnras.com\/drug\/?attachment_id=97674#main\" rel=\"attachment wp-att-97674\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-97674\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/08\/Savi-Direin-50-12.jpg\" alt=\"Savi Direin 50\" width=\"1200\" height=\"768\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/08\/Savi-Direin-50-12.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/08\/Savi-Direin-50-12-625x400.jpg 625w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/08\/Savi-Direin-50-12-768x492.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/08\/Savi-Direin-50-12-350x224.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/a><figcaption id=\"caption-attachment-97674\" class=\"wp-caption-text\">Thu\u1ed1c Savi Direin 50 &#8211; \u0110i\u1ec1u tr\u1ecb vi\u00eam x\u01b0\u01a1ng kh\u1edbp<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Savi Direin 50<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Ho\u1ea1t ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng t\u0103ng c\u01b0\u1eddng t\u00e1i t\u1ea1o s\u1ee5n kh\u1edbp, ng\u0103n ng\u1eeba tho\u00e1i h\u00f3a kh\u1edbp.<\/p>\n<p>C\u01a1 ch\u1ebf: \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p interleukin-1 beta, t\u0103ng c\u01b0\u1eddng s\u1ea3n sinh nitrous oxide. Nghi\u00ean c\u1ee9u hi\u1ec7n \u0111\u1ea1i \u0111\u00e3 kh\u1eb3ng \u0111\u1ecbnh t\u00e1c d\u1ee5ng c\u1ee7a Diacerein trong ch\u1ee9ng tho\u00e1i h\u00f3a kh\u1edbp, h\u1ed3i ph\u1ee5c s\u1ee5n kh\u1edbp, k\u00edch th\u00edch s\u1ea3n sinh TGF-beta 1 v\u00e0 2.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu:<\/p>\n<ul>\n<li>Kh\u1ea3 d\u1ee5ng sinh h\u1ecdc kho\u1ea3ng 35 &#8211; 55%.<\/li>\n<li>Th\u1ee9c \u0103n k\u00e9o d\u00e0i th\u1eddi gian \u0111\u1ea1t Cmax nh\u01b0ng l\u1ea1i th\u00fac \u0111\u1ea9y h\u1ea5p thu nhanh h\u01a1n.<\/li>\n<\/ul>\n<p>Ph\u00e2n b\u1ed1: Rhein li\u00ean k\u1ebft kho\u1ea3ng 99% v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng v\u00e0 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 kho\u1ea3ng 0,3 &#8211; 3 mg\/l trong ho\u1ea1t d\u1ecbch.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: ho\u00e0n to\u00e0n \u1edf gan -&gt; deacetylate rhein c\u00f3 ho\u1ea1t t\u00ednh. H\u1ea7u h\u1ebft c\u00e1c ch\u1ea5t chuy\u1ec3n ho\u00e1 c\u00f3 T1\/2 huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 7 \u2013 8 gi\u1edd.<\/p>\n<p>B\u00e0i ti\u1ebft: d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a kho\u1ea3ng 35 &#8211; 60% qua n\u01b0\u1edbc ti\u1ec3u (trong \u0111\u00f3 d\u1ea1ng rhein t\u1ef1 do chi\u1ebfm 20% v\u00e0 d\u1ea1ng li\u00ean h\u1ee3p l\u00e0 80%).<\/p>\n<h2>Thu\u1ed1c Savi Direin 50 ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00ec?<\/h2>\n<p>Vi\u00eam kh\u1edbp x\u01b0\u01a1ng.<\/p>\n<p>Tho\u00e1i h\u00f3a kh\u1edbp.<\/p>\n<p>M\u1ed9t s\u1ed1 ch\u1ee9ng b\u1ec7nh x\u01b0\u01a1ng kh\u1edbp kh\u00e1c.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Savi Direin 50<\/h2>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>\u0110\u1ec3 \u0111\u1ea1t h\u1ea5p thu t\u1ed1t nh\u1ea5t n\u00ean u\u1ed1ng Savi Direin 50 trong b\u1eefa \u0103n.<\/p>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Ng\u01b0\u1eddi l\u1edbn: Trong 2-4 tu\u1ea7n \u0111\u1ea7u ti\u00ean u\u1ed1ng 1 vi\u00ean Savi Direin 50 v\u00e0o b\u1eefa t\u1ed1i, sau \u0111\u00f3 2 vi\u00ean\/ng\u00e0y, chia l\u00e0m 2 l\u1ea7n u\u1ed1ng.<\/p>\n<p>Suy th\u1eadn n\u1eb7ng: gi\u1ea3m n\u1eeda li\u1ec1u <strong>Diacerein 50<\/strong>.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Savi Direin 50 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Tr\u1ebb nh\u1ecf h\u01a1n 15 tu\u1ed5i.<\/p>\n<p>M\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a Savi Direin 50 hay d\u1eabn xu\u1ea5t anthraquinon.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Savi Direin 50<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Kh\u1edfi \u0111\u1ea7u d\u00f9ng Savi Direin 50 li\u1ec1u th\u1ea5p n\u1ebfu kh\u00f4ng c\u00f3 th\u1ec3 g\u00e2y ti\u00eau ch\u1ea3y n\u1eb7ng.<\/p>\n<p>B\u1ea5t k\u1ec3 tr\u01b0\u1eddng h\u1ee3p n\u00e0o c\u0169ng c\u1ea7n \u0111\u1ecbnh k\u1ef3 ki\u1ec3m tra men gan 2 l\u1ea7n\/n\u0103m.<\/p>\n<p>Kh\u00f4ng ph\u1ed1i h\u1ee3p Savi Direin 50 v\u1edbi thu\u1ed1c nhu\u1eadn tr\u00e0ng.<\/p>\n<p>T\u00edch l\u0169y thu\u1ed1c c\u00f3 th\u1ec3 x\u1ea3y ra trong tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n x\u01a1 gan d\u00f9ng \u0111a li\u1ec1u, do v\u1eady tr\u01b0\u1edbc khi d\u00f9ng thu\u1ed1c c\u1ea7n th\u1eed nghi\u1ec7m cho c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng thu\u1ed9c di\u1ec7n n\u00e0y.<\/p>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u s\u1eed d\u1ee5ng Savi Direin 50 cho b\u1ec7nh nhi.<\/p>\n<p>Ng\u01b0\u1eddi gi\u00e0 \u0111\u00e3 c\u00f3 th\u1eed nghi\u1ec7m cho s\u1eed d\u1ee5ng &gt; 100mg diacerein\/ng\u00e0y.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p \u0111i ngo\u00e0i ph\u00e2n l\u1ecfng (chi\u1ebfm 37%), \u0111au b\u1ee5ng d\u01b0\u1edbi (m\u1ed9t v\u00e0i tr\u01b0\u1eddng h\u1ee3p), bi\u1ebfn m\u00e0u n\u01b0\u1edbc ti\u1ec3u (14,4%), kali huy\u1ebft gi\u1ea3m (\u0111\u00e3 g\u1eb7p 1 tr\u01b0\u1eddng h\u1ee3p duy nh\u1ea5t), h\u1ed9i ch\u1ee9ng Lyell, nhi\u1ec5m \u0111\u1ed9c gan.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n<p>Ch\u01b0a ph\u00e1t hi\u1ec7n t\u01b0\u01a1ng t\u00e1c thu\u1ed1c n\u00e0o x\u1ea3y ra c\u1ee7a Savi Direin 50 tr\u00ean l\u00e2m s\u00e0ng.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n<p>\u0110\u1ec3 an to\u00e0n, kh\u00f4ng n\u00ean d\u00f9ng Savi Direin 50 trong th\u1eddi k\u1ef3 mang thai v\u00e0 cho con b\u00fa.<\/p>\n<h3>\u1ea2nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng: ti\u00eau ch\u1ea3y n\u1eb7ng.<\/p>\n<p>H\u1ed7 tr\u1ee3 c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i v\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng g\u1eb7p ph\u1ea3i.<\/p>\n<h2>Thu\u1ed1c SaviDirein 50 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c Savi Direin 50 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Savi Direin 50 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb gi\u1ed1ng v\u1edbi thu\u1ed1c Savi Direin 50 nh\u01b0:<\/p>\n<ul>\n<li>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/paincerin-50mg\/\">Paincerin 50mg<\/a> do One Pharma s\u1ea3n xu\u1ea5t, ch\u1ee9a Diacerein 50mg, d\u01b0\u1edbi d\u1ea1ng vi\u00ean nang c\u1ee9ng, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng gi\u00fap h\u1ea1n ch\u1ebf h\u1ee7y kh\u1edbp, ng\u0103n ng\u1eeba tho\u00e1i h\u00f3a c\u00e1c kh\u1edbp (nh\u01b0 g\u1ed1i, h\u00f4ng,&#8230;). M\u1ed7i h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean c\u00f3 gi\u00e1 370.000\u0111.<\/li>\n<li>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/artreil-50\/\">Artreil 50<\/a> l\u00e0 s\u1ea3n ph\u1ea9m c\u1ee7a C\u00f4ng ty TNHH d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa, ch\u1ee9a Diacerein 50mg, d\u01b0\u1edbi d\u1ea1ng vi\u00ean nang c\u1ee9ng, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb tho\u00e1i h\u00f3a kh\u1edbp do gi\u1ea3m ti\u00eau h\u1ee7y collagen. M\u1ed7i h\u1ed9p 10 v\u1ec9 x 10 vi\u00ean c\u00f3 gi\u00e1 b\u00e1n 650.000\u0111.<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>Karel Pavelka v\u00e0 c\u1ed9ng s\u1ef1. (Th\u00e1ng 02 n\u0103m 2016). <em>Diacerein: Benefits, Risks and Place in the Management of Osteoarthritis. An Opinion-Based Report from the ESCEO.<\/em> Truy c\u1eadp ng\u00e0y 12 th\u00e1ng 08 n\u0103m 2024, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/26849131\/<\/li>\n<li>Tania S A Fidelix v\u00e0 c\u1ed9ng s\u1ef1. (Ng\u00e0y 10 th\u00e1ng 02 n\u0103m 2014). <em>Diacerein for osteoarthritis.<\/em> Truy c\u1eadp ng\u00e0y 12 th\u00e1ng 08 n\u0103m 2024, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24515444\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/24515444\/<\/a><\/li>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i b\u1ea3n PDF <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/08\/Savi-Direin-50-vnras.pdf\">T\u1ea0I \u0110\u00c2Y<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Savi Direin 50 ch\u1ee9a Diacerein v\u1edbi h\u00e0m l\u01b0\u1ee3ng 50mg d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp x\u01b0\u01a1ng, tho\u00e1i h\u00f3a kh\u1edbp v\u00e0 m\u1ed9t s\u1ed1 ch\u1ee9ng b\u1ec7nh x\u01b0\u01a1ng kh\u1edbp kh\u00e1c<\/p>\n","protected":false},"author":1,"featured_media":97663,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-97662","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/97662","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=97662"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/97663"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=97662"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=97662"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=97662"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}