{"id":95930,"date":"2024-07-31T21:33:59","date_gmt":"2024-07-31T14:33:59","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=95930"},"modified":"2025-07-24T13:30:56","modified_gmt":"2025-07-24T06:30:56","slug":"sife-100","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/sife-100\/","title":{"rendered":"Sife 100"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/sife-100\/\">Sife 100<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Hetero Labs Limited, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18539-14<\/strong><\/p>\n<h2>Thu\u1ed1c Sife 100 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Thu\u1ed1c <strong>Sife 100<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Sildenafil (d\u01b0\u1edbi d\u1ea1ng Sidenafil citrat) 100 mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-18539-14<br \/>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p l\u1edbn x 5 h\u1ed9p nh\u1ecf x 1 v\u1ec9 x 4 vi\u00ean<br \/>\nXu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Sife 100<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Sildenafil c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf phosphodiesterase typ 5 (PDE5) c\u1ee7a guanosin monophosphat v\u00f2ng (cGMP) v\u1edbi m\u1ee9c \u0111\u1ed9 m\u1ea1nh v\u00e0 \u0111\u1eb7c hi\u1ec7u, \u0111\u00e2y l\u00e0 enzym l\u00e0m tho\u00e1i bi\u1ebfn cGMP. V\u00ec v\u1eady sildenafil c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m t\u0103ng cGMP b\u00ean trong t\u1ebf b\u00e0o c\u01a1 tr\u01a1n t\u1ea1i v\u1ecb tr\u00ed m\u1ea1ch m\u00e1u ph\u1ed5i. \u1ede nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng t\u0103ng huy\u1ebft \u00e1p \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i l\u00e0m gi\u00e3n m\u1ea1ch m\u00e1u \u1edf ph\u1ed5i, v\u00e0 c\u0169ng l\u00e0m gi\u00e3n m\u1ea1ch \u1edf to\u00e0n th\u00e2n nh\u01b0ng \u00edt h\u01a1n.<br \/>\n\u1ede ng\u01b0\u1eddi r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng, ph\u1ea3i c\u00f3 k\u00edch th\u00edch t\u00ecnh d\u1ee5c th\u00ec sidenafil m\u1edbi c\u00f3 t\u00e1c d\u1ee5ng. Sildenafil gi\u00fap t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a oxyd nitric do c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf PDE-5 v\u00e0 l\u00e0m t\u0103ng m\u1ee9c cGMP trong th\u1ec3 hang n\u00ean g\u00e2y c\u01b0\u01a1ng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: h\u1ea5p thu nhanh, sinh kh\u1ea3 d\u1ee5ng c\u1ee7a d\u01b0\u1ee3c ch\u1ea5t n\u00e0y kho\u1ea3ng 41% sau khi u\u1ed1ng, t\u1ed1c \u0111\u1ed9 h\u1ea5p thu b\u1ecb gi\u1ea3m khi u\u1ed1ng c\u00f9ng th\u1ee9c \u0103n.<br \/>\nChuy\u1ec3n h\u00f3a: chuy\u1ec3n h\u00f3a th\u00f4ng qua 2 con \u0111\u01b0\u1eddng l\u00e0 CYP3A4 v\u00e0 CYP2C9, do qu\u00e1 tr\u00ecnh N -demethyl h\u00f3a<br \/>\nTh\u1ea3i tr\u1eeb: t \u00bd c\u1ee7a pha cu\u1ed1i c\u00f9ng l\u00e0 3-5h.<\/p>\n<h2>Thu\u1ed1c Sife 100 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<figure id=\"attachment_95942\" aria-describedby=\"caption-attachment-95942\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/vnras.com\/drug\/?attachment_id=95942#main\" rel=\"attachment wp-att-95942\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-95942\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/07\/sife-100-10.jpg\" alt=\"sife-100\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/07\/sife-100-10.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/07\/sife-100-10-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/07\/sife-100-10-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/07\/sife-100-10-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/a><figcaption id=\"caption-attachment-95942\" class=\"wp-caption-text\">sife-100<\/figcaption><\/figure>\n<p>\u0110i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng.<\/p>\n<h2>\u0110\u1ed1i t\u01b0\u1ee3ng s\u1eed d\u1ee5ng<\/h2>\n<p>Nam gi\u1edbi g\u1eb7p t\u00ecnh tr\u1ea1ng r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Sife 100<\/h2>\n<p>Ng\u01b0\u1eddi d\u00f9ng c\u00f3 th\u1ec3 u\u1ed1ng Sife tr\u01b0\u1edbc khi quan h\u1ec7 t\u1eeb 0,5h &#8211; 4h, li\u1ec1u th\u01b0\u1eddng d\u00f9ng l\u00e0 50mg tr\u01b0\u1edbc 1h. \u0110\u00f4i khi d\u00f9ng li\u1ec1u 25mg ho\u1eb7c 100mg t\u00f9y t\u1eebng tr\u01b0\u1eddng h\u1ee3p. Ch\u1ec9 s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng, m\u1ed7i ng\u00e0y 1 l\u1ea7n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Sife 100 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u00f9ng nitrat h\u1eefu c\u01a1.<br \/>\nD\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf CYP 3A4 m\u1ea1nh<br \/>\nNg\u01b0\u1eddi gi\u1ea3m th\u1ecb l\u1ef1c m\u1ed9t m\u1eaft<br \/>\nTi\u1ec1n s\u1eed m\u1edbi b\u1ecb \u0111\u1ed9t qu\u1ef5<br \/>\nNh\u1ed3i m\u00e1u c\u01a1 tim<br \/>\nH\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng khi m\u1edbi d\u00f9ng thu\u1ed1c.<br \/>\nSuy gan n\u1eb7ng<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Sife 100<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Th\u1eadn tr\u1ecdng v\u1edbi nh\u1eefng ng\u01b0\u1eddi \u0111\u00e3 b\u1ecb b\u1ec7nh tim m\u1ea1ch, ng\u01b0\u1eddi g\u1eb7p v\u1ea5n \u0111\u1ec1 v\u1ec1 \u0111\u01b0\u1eddng t\u1ed1ng m\u00e1u ra t\u1eeb th\u1ea5t tr\u00e1i b\u1ecb ngh\u1ebdn, ng\u01b0\u1eddi c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 h\u1ec7 t\u1ef1 \u0111\u1ed9ng \u0111i\u1ec1u h\u00f2a huy\u1ebft \u00e1p.<br \/>\nTh\u1eadn tr\u1ecdng khi d\u00f9ng Sife v\u1edbi ng\u01b0\u1eddi c\u00f3 b\u1ec7nh li\u00ean quan huy\u1ebft \u00e1p, thi\u1ebfu h\u1ee5t th\u1ec3 d\u1ecbch, r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng t\u1ef1 \u0111\u1ed9ng.<br \/>\nThu\u1ed1c Sife c\u00f3 th\u1ec3 g\u00e2y cho\u00e1ng v\u00e1ng, nh\u00ecn m\u1edd n\u00ean c\u1ea9n th\u1eadn khi l\u00e1i xe<br \/>\nN\u1ebfu d\u01b0\u01a1ng v\u1eadt c\u01b0\u01a1ng c\u1ee9ng &gt;4h th\u00ec n\u00ean \u0111i kh\u00e1m.<br \/>\n\u0110\u1ed1i t\u01b0\u1ee3ng \u0111ang d\u00f9ng li\u1ec7u ph\u00e1p bosentan, hay vi\u00eam v\u00f5ng m\u1ea1c s\u1eafc t\u1ed1, \u0111au th\u1eaft ng\u1ef1c n\u00ean th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c Sife.<br \/>\n\u0110\u1ec3 thu\u1ed1c Sife tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em<br \/>\nB\u1ea3o qu\u1ea3n Sife \u1edf n\u01a1i tr\u00e1nh \u1ea9m<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<h4>R\u1ea5t th\u01b0\u1eddng g\u1eb7p:<\/h4>\n<p>\u0110au \u0111\u1ea7u<br \/>\nGi\u00e3n m\u1ea1ch<\/p>\n<h4>Th\u01b0\u1eddng g\u1eb7p:<\/h4>\n<p>Ch\u00f3ng m\u1eb7t.<br \/>\nTh\u1ecb l\u1ef1c b\u1ea5t th\u01b0\u1eddng; lo\u1ea1n s\u1eafc gi\u00e1c<br \/>\nTim \u0111\u1eadp nhanh.<br \/>\nVi\u00eam m\u0169i (xung huy\u1ebft m\u0169i).<br \/>\nKh\u00f3 ti\u00eau.<\/p>\n<h4>Ngo\u00e0i ra, c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n sau \u0111\u00e2y<\/h4>\n<p>Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn .<br \/>\n\u0110\u1ed9ng kinh, t\u00e1i ph\u00e1t \u0111\u1ed9ng kinh.<br \/>\nN\u00f4n<br \/>\nCh\u1ee9ng tim \u0111\u1eadp nhanh.<br \/>\nH\u1ea1 huy\u1ebft \u00e1p,<br \/>\nNg\u1ea5t<br \/>\nCh\u1ea3y m\u00e1u cam.<br \/>\n\u0110au m\u1eaft<br \/>\nC\u01b0\u01a1ng d\u01b0\u01a1ng k\u00e9o d\u00e0i<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Thu\u1ed1c kh\u00e1ng vitamin K: l\u00e0m t\u0103ng t\u1ef7 l\u1ec7 xu\u1ea5t huy\u1ebft \u1edf ng\u01b0\u1eddi t\u0103ng huy\u1ebft \u00e1p \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i<br \/>\nCh\u1ea5t \u1ee9c ch\u1ebf protease ritonavir: l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 sildenafil trong huy\u1ebft thanh.<br \/>\nC\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf PDE5, v\u00e0 c\u00e1c thu\u1ed1c ch\u1eb9n alpha-adrenergic: g\u00e2y h\u1ea1 huy\u1ebft \u00e1p.<br \/>\nCh\u1ea5t \u1ee9c ch\u1ebf CYP 3A4 v\u00e0 CYP 2C9: l\u00e0m gi\u1ea3m s\u1ef1 thanh th\u1ea3i sildenafil, v\u00e0 ng\u01b0\u1ee3c l\u1ea1i.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef kh\u00f4ng d\u00f9ng thu\u1ed1c Sife n\u00e0y.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<h4>Tri\u1ec7u ch\u1ee9ng<\/h4>\n<p>&#8211; Nh\u1ee9c \u0111\u1ea7u<br \/>\n&#8211; Ch\u00f3ng m\u1eb7t<br \/>\n&#8211; Gi\u1ea3m th\u1ecb gi\u00e1c<br \/>\n&#8211; Xung huy\u1ebft m\u0169i<br \/>\n&#8211; Kh\u00f3 ti\u00eau<\/p>\n<h4>\u0110i\u1ec1u tr\u1ecb<\/h4>\n<p>Th\u1ef1c hi\u1ec7n c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e2ng \u0111\u1ee1<\/p>\n<h2>Thu\u1ed1c Sife 100 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c<strong> Sife 100 ch\u00ednh h\u00e3ng<\/strong> hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<br \/>\nK\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<br \/>\n1. Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/thuoc-sefi-50\/\">Sife-50<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Hetero Labs Limited, c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Sildenafil 50mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c L\u01b0u V\u0103n Ho\u00e0ng v\u1edbi gi\u00e1 95000 \u0111\u1ed3ng.<br \/>\n<a href=\"https:\/\/vnras.com\/drug\/hindgra-100mg\/\">2. Hindgra 100mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Axon Drugs Private Ltd \u2013 \u1ea4n \u0110\u1ed9, c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Sildenafil 100mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c L\u01b0u V\u0103n Ho\u00e0ng v\u1edbi gi\u00e1 120000 \u0111\u1ed3ng<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Mikkel Fode 1, Christian Fuglesang S Jensen 2, Peter Busch \u00d8stergren. (\u0110\u0103ng ng\u00e0y 5 th\u00e1ng 3 n\u0103m 2019). Sildenafil in postprostatectomy erectile dysfunction (perspective). Truy c\u1eadp ng\u00e0y 31 th\u00e1ng 7 n\u0103m 2024, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30837719\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30837719\/<\/a><br \/>\nT\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng do C\u1ee5c qu\u1ea3n l\u00fd d\u01b0\u1ee3c, Nh\u00e0 s\u1ea3n xu\u1ea5t c\u00f4ng b\u1ed1 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/07\/huong-dan-su-dung-sife-100-vnras-1.pdf\">t\u1ea1i \u0111\u00e2y.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sife 100 l\u00e0 s\u1ea3n ph\u1ea9m c\u1ee7a C\u00f4ng ty Hetero Labs Limited, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18539-14, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng.<\/p>\n","protected":false},"author":1,"featured_media":95933,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-95930","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/95930","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=95930"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/95933"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=95930"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=95930"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=95930"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}