﻿{"id":73435,"date":"2024-05-13T16:54:25","date_gmt":"2024-05-13T09:54:25","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=73435"},"modified":"2025-07-24T13:40:31","modified_gmt":"2025-07-24T06:40:31","slug":"thuoc-murkars-100mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-murkars-100mg\/","title":{"rendered":"Murkars"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m <a href=\"https:\/\/vnras.com\/drug\/thuoc-murkars-100mg\/\">thu\u1ed1c Murkars<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n H\u00f3a d\u01b0\u1ee3c Vi\u1ec7t Nam, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-34440-20<\/b><\/p>\n<p>&nbsp;<\/p>\n<h2><span style=\"font-weight: 400;\">Murkars l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400;\"><strong>Thu\u1ed1c Murkars<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itraconazole (d\u01b0\u1edbi d\u1ea1ng Itraconazole pellets 22,0%) 100mg<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang c\u1ee9ng<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">S\u0110K: VD-34440-20<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 v\u1ec9 x 10 vi\u00ean<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Murkars<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itraconazole ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch li\u00ean k\u1ebft v\u1edbi enzyme alpha-demethylase 14 c\u1ee7a n\u1ea5m, ng\u0103n ch\u1eb7n ph\u1ea3n \u1ee9ng kh\u1eed methyl h\u00f3a alpha-14 c\u1ea7n thi\u1ebft \u0111\u1ec3 t\u1ea1o ra ergosterol t\u1eeb lanosterol.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">S\u1ef1 r\u1ed1i lo\u1ea1n m\u00e0ng t\u1ebf b\u00e0o n\u1ea5m do m\u1ea5t ergosterol khi\u1ebfn t\u0103ng t\u00ednh th\u1ea5m v\u00e0 v\u1ee1 m\u00e0ng, d\u1eabn \u0111\u1ebfn nhi\u1ec1u t\u00e1c \u0111\u1ed9ng khi\u1ebfn n\u1ea5m ti\u00eau vong:\u00a0<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Enzyme g\u1eafn m\u00e0ng b\u1ecb thay \u0111\u1ed5i ho\u1ea1t \u0111\u1ed9ng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">G\u00e2y r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng t\u1ebf b\u00e0o.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">D\u1eabn \u0111\u1ebfn ch\u1ebft t\u1ebf b\u00e0o n\u1ea5m.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ngo\u00e0i ra, Itraconazole c\u00f2n c\u00f3 m\u1ed9t ch\u1ea5t chuy\u1ec3n h\u00f3a ho\u1ea1t \u0111\u1ed9ng l\u00e0 hydroxy-itraconazole, c\u0169ng g\u00f3p ph\u1ea7n v\u00e0o t\u00e1c d\u1ee5ng ch\u1ed1ng n\u1ea5m.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">H\u1ea5p thu: Nhanh, \u0111\u1ea1t Cmax sau khi u\u1ed1ng 2-5 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng 55%, t\u1ed1t nh\u1ea5t khi axit d\u1ea1 d\u00e0y v\u1eeba \u0111\u1ee7.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ph\u00e2n ph\u1ed1i: Th\u1ec3 t\u00edch ph\u00e2n ph\u1ed1i l\u1edbn (h\u01a1n 700 L), \u01b0a m\u1ee1, n\u1ed3ng \u0111\u1ed9 cao trong m\u00f4, da, gan, ph\u1ed5i, th\u1eadn, x\u01b0\u01a1ng. Li\u00ean k\u1ebft protein cao (99,8%), 0,2% d\u1ea1ng t\u1ef1 do.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chuy\u1ec3n h\u00f3a: Chuy\u1ec3n h\u00f3a m\u1ea1nh \u1edf gan b\u1edfi CYP3A4, t\u1ea1o ra h\u01a1n 30 ch\u1ea5t chuy\u1ec3n h\u00f3a (ch\u1ee7 y\u1ebfu hydroxyitraconazol c\u00f3 ho\u1ea1t t\u00ednh t\u01b0\u01a1ng \u0111\u01b0\u01a1ng).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">B\u00e0i ti\u1ebft: Ch\u1ee7 y\u1ebfu qua ph\u00e2n (54%) v\u00e0 n\u01b0\u1edbc ti\u1ec3u (35%) d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng ho\u1ea1t t\u00ednh trong 1 tu\u1ea7n. N\u1ed3ng \u0111\u1ed9 trong da 14-28 ng\u00e0y, m\u00f3ng 6 th\u00e1ng sau khi ng\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">N\u1eeda \u0111\u1eddi: 16-28 gi\u1edd (li\u1ec1u \u0111\u01a1n), 34-42 gi\u1edd (li\u1ec1u l\u1eb7p l\u1ea1i). \u0110\u1ed9 thanh th\u1ea3i trung b\u00ecnh 278 mL\/ph\u00fat (ti\u00eam t\u0129nh m\u1ea1ch), gi\u1ea3m \u1edf li\u1ec1u cao do b\u00e3o h\u00f2a chuy\u1ec3n h\u00f3a gan.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Thu\u1ed1c Murkars \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">N\u1ea5m x\u00e2m l\u1ea5n: Blastomycosis, Histoplasmosis, Aspergillosis, Paracoccidioidomycosis, Coccidioidomycosis.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">N\u1ea5m b\u1ec1 m\u1eb7t: n\u1ea5m m\u00f3ng (onychomycosis), vi\u00eam da ti\u1ebft b\u00e3 nh\u1eddn (seborrheic dermatitis), n\u1ea5m da kh\u00e1c (lang ben,&#8230;).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">N\u1ea5m Candida<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c <\/span><b>Murkars<\/b><span style=\"font-weight: 400;\"> c\u00f2n \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 d\u1ef1 ph\u00f2ng cho b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh nhi\u1ec5m n\u1ea5m h\u1ec7 th\u1ed1ng, bao g\u1ed3m:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">B\u1ec7nh nh\u00e2n HIV<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">B\u1ec7nh nh\u00e2n \u0111ang h\u00f3a tr\u1ecb li\u1ec7u<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">B\u1ec7nh nh\u00e2n sau gh\u00e9p t\u1ea1ng<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Murkars<\/span><\/h2>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr style=\"height: 50px;\">\n<td style=\"height: 50px; width: 18.7454%;\"><span style=\"font-weight: 400;\">Ch\u1ec9 \u0111\u1ecbnh<\/span><\/td>\n<td style=\"height: 50px; width: 18.893%;\"><span style=\"font-weight: 400;\">Li\u1ec1u l\u01b0\u1ee3ng<\/span><\/td>\n<td style=\"height: 50px; width: 62.214%;\"><span style=\"font-weight: 400;\">L\u01b0u \u00fd<\/span><\/td>\n<\/tr>\n<tr style=\"height: 50px;\">\n<td style=\"height: 50px; width: 18.7454%;\"><span style=\"font-weight: 400;\">N\u1ea5m m\u00f3ng tay<\/span><\/td>\n<td style=\"height: 50px; width: 18.893%;\"><span style=\"font-weight: 400;\">2 vi\u00ean x 2 l\u1ea7n\/ng\u00e0y\u00a0 x 7 ng\u00e0y<\/span><\/td>\n<td style=\"height: 50px; width: 62.214%;\"><span style=\"font-weight: 400;\">Ngh\u1ec9 21 ng\u00e0y sau m\u1ed7i \u0111\u1ee3t. Li\u1ec1u tr\u00ecnh 2 \u0111\u1ee3t cho b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 122px;\">\n<td style=\"height: 122px; width: 18.7454%;\"><span style=\"font-weight: 400;\">Nhi\u1ec5m n\u1ea5m<\/span><\/td>\n<td style=\"height: 122px; width: 18.893%;\"><span style=\"font-weight: 400;\">2 vi\u00ean x 1-2 l\u1ea7n\/ng\u00e0y\u00a0<\/span><\/td>\n<td style=\"height: 122px; width: 62.214%;\"><span style=\"font-weight: 400;\">B\u1eaft \u0111\u1ea7u v\u1edbi 2 vi\u00ean x 2 l\u1ea7n\/ng\u00e0y x 3 ng\u00e0y cho tr\u01b0\u1eddng h\u1ee3p nguy hi\u1ec3m \u0111\u1ebfn t\u00ednh m\u1ea1ng.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">T\u1ed1i \u0111a 6 vi\u00ean\/ng\u00e0y.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Chia nh\u1ecf li\u1ec1u, u\u1ed1ng c\u00f9ng th\u1ee9c \u0103n.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 72px;\">\n<td style=\"height: 72px; width: 18.7454%;\"><span style=\"font-weight: 400;\">N\u1ea5m m\u00f3ng ch\u00e2n<\/span><\/td>\n<td style=\"height: 72px; width: 18.893%;\"><span style=\"font-weight: 400;\">2 vi\u00ean\u00a0 x 1 l\u1ea7n\/ng\u00e0y x 12 tu\u1ea7n<\/span><\/td>\n<td style=\"height: 72px; width: 62.214%;\"><\/td>\n<\/tr>\n<tr style=\"height: 86px;\">\n<td style=\"height: 86px; width: 18.7454%;\"><span style=\"font-weight: 400;\">Blastomycosis<\/span><\/td>\n<td style=\"height: 86px; width: 18.893%;\"><span style=\"font-weight: 400;\">2 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/span><\/td>\n<td style=\"height: 86px; width: 62.214%;\"><span style=\"font-weight: 400;\">T\u0103ng 1 vi\u00ean\/l\u1ea7n n\u1ebfu kh\u00f4ng hi\u1ec7u qu\u1ea3, chia nh\u1ecf li\u1ec1u &gt; 2 vi\u00ean\/ng\u00e0y.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">T\u1ed1i \u0111a 6 vi\u00ean\/ng\u00e0y.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 86px;\">\n<td style=\"height: 86px; width: 18.7454%;\"><span style=\"font-weight: 400;\">Histoplasmosis<\/span><\/td>\n<td style=\"height: 86px; width: 18.893%;\"><span style=\"font-weight: 400;\">2 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/span><\/td>\n<td style=\"height: 86px; width: 62.214%;\"><span style=\"font-weight: 400;\">T\u0103ng 1 vi\u00ean\/l\u1ea7n n\u1ebfu kh\u00f4ng hi\u1ec7u qu\u1ea3, chia nh\u1ecf li\u1ec1u &gt; 2 vi\u00ean\/ng\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">T\u1ed1i \u0111a 4 vi\u00ean\/ng\u00e0y.\u00a0<\/span><\/td>\n<\/tr>\n<tr style=\"height: 50px;\">\n<td style=\"height: 50px; width: 18.7454%;\"><span style=\"font-weight: 400;\">Aspergillosis x\u00e2m l\u1ea5n<\/span><\/td>\n<td style=\"height: 50px; width: 18.893%;\"><span style=\"font-weight: 400;\">2 &#8211; 4 vi\u00ean\/ng\u00e0y<\/span><\/td>\n<td style=\"height: 50px; width: 62.214%;\"><span style=\"font-weight: 400;\">Chia nh\u1ecf li\u1ec1u &gt; 2 vi\u00ean\/ng\u00e0y.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 50px;\">\n<td style=\"height: 50px; width: 18.7454%;\"><span style=\"font-weight: 400;\">Nhi\u1ec5m n\u1ea5m n\u00f4ng<\/span><\/td>\n<td style=\"height: 50px; width: 18.893%;\"><span style=\"font-weight: 400;\">1 vi\u00ean x 1-2 l\u1ea7n\/ng\u00e0y<\/span><\/td>\n<td style=\"height: 50px; width: 62.214%;\"><span style=\"font-weight: 400;\">Li\u1ec1u t\u1ed1i \u0111a 6 vi\u00ean\/ng\u00e0y, chia nh\u1ecf li\u1ec1u &gt; 2 vi\u00ean.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 50px;\">\n<td style=\"height: 50px; width: 18.7454%;\"><span style=\"font-weight: 400;\">Coccidioidomycosis<\/span><\/td>\n<td style=\"height: 50px; width: 18.893%;\"><span style=\"font-weight: 400;\">2 vi\u00ean x 12 gi\u1edd<\/span><\/td>\n<td style=\"height: 50px; width: 62.214%;\"><\/td>\n<\/tr>\n<tr style=\"height: 72px;\">\n<td style=\"height: 72px; width: 18.7454%;\"><span style=\"font-weight: 400;\">Sporotrichosis da\/b\u1ea1ch huy\u1ebft<\/span><\/td>\n<td style=\"height: 72px; width: 18.893%;\"><span style=\"font-weight: 400;\">2 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/span><\/td>\n<td style=\"height: 72px; width: 62.214%;\"><span style=\"font-weight: 400;\">C\u00f3 th\u1ec3 t\u0103ng 2 vi\u00ean x 2 l\u1ea7n\/ng\u00e0y. Duy tr\u00ec 2-4 tu\u1ea7n sau khi t\u1ed5n th\u01b0\u01a1ng l\u00e0nh. \u01afu ti\u00ean dung d\u1ecbch u\u1ed1ng.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400;\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Murkars trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Suy tim ho\u1eb7c c\u00f3 ti\u1ec1n s\u1eed suy tim<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Suy gan ho\u1eb7c b\u1ec7nh gan<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Mang thai: Do nguy c\u01a1 g\u00e2y qu\u00e1i thai v\u00e0 \u0111\u1ed9c cho ph\u00f4i.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">D\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c sau:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cisapride\/Astemizole\/Terfenadine: G\u00e2y r\u1ed1i lo\u1ea1n nh\u1ecbp tim nghi\u00eam tr\u1ecdng.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Triazolam\/Midazolam: K\u00e9o d\u00e0i t\u00e1c d\u1ee5ng an th\u1ea7n.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thu\u1ed1c tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng \u0111\u01b0\u1eddng u\u1ed1ng: G\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft nghi\u00eam tr\u1ecdng.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Murkars<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ng\u01b0ng thu\u1ed1c ngay n\u1ebfu:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Xu\u1ea5t hi\u1ec7n b\u1ec7nh th\u1ea7n kinh do itraconazole.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">C\u00f3 d\u1ea5u hi\u1ec7u suy tim sung huy\u1ebft.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u0110\u00e1nh gi\u00e1 nguy c\u01a1 d\u1ecb \u1ee9ng tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nhi\u1ec5m n\u1ea5m Candida to\u00e0n th\u00e2n.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ng\u01b0\u1eddi c\u00f3 v\u1ea5n \u0111\u1ec1 di truy\u1ec1n hi\u1ebfm g\u1eb7p<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ng\u01b0\u1eddi t\u1eebng c\u00f3 suy tim sung huy\u1ebft<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u0103ng men gan, b\u1ec7nh gan ho\u1ea1t \u0111\u1ed9ng ho\u1eb7c t\u1ed5n th\u01b0\u01a1ng gan do thu\u1ed1c tr\u01b0\u1edbc \u0111\u00f3 (tr\u1eeb khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi r\u1ee7i ro).<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">C\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd enzym gan trong huy\u1ebft thanh, \u0111\u1eb7c bi\u1ec7t l\u00e0 b\u1ec7nh nh\u00e2n d\u00f9ng thu\u1ed1c li\u00ean t\u1ee5c tr\u00ean 1 th\u00e1ng.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng t\u00e2m th\u1ea5t r\u1ed1i lo\u1ea1n<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Th\u01b0\u1eddng g\u1eb7p:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a: \u1ec8a l\u1ecfng, \u0111i ngo\u00e0i, tr\u1edb, \u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u0110au \u0111\u1ea7u, ph\u00e1t ban.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u00cdt g\u1eb7p:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u0110\u1ed9c t\u00ednh tim: Gi\u1ea3m co b\u00f3p tim, c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn suy tim (Nguy c\u01a1 t\u0103ng khi d\u00f9ng li\u1ec1u cao &gt; 400mg\/ng\u00e0y). M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p c\u1ea7n c\u1ea5y gh\u00e9p tim.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nhi\u1ec5m \u0111\u1ed9c gan: T\u0103ng men gan t\u1ea1m th\u1eddi.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u0103ng huy\u1ebft \u00e1p: Kh\u00f3 ki\u1ec3m so\u00e1t \u1edf b\u1ec7nh nh\u00e2n cao huy\u1ebft \u00e1p.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/span><\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Thu\u1ed1c<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Warfarin<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">T\u0103ng t\u00e1c d\u1ee5ng ch\u1ed1ng \u0111\u00f4ng<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Triazolam, Midazolam, Diazepam<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">T\u0103ng t\u00e1c d\u1ee5ng an th\u1ea7n<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Thu\u1ed1c u\u1ed1ng ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">H\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft n\u1eb7ng<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Thu\u1ed1c kh\u00e1ng H2, kh\u00e1ng acid, Sucralfate, Omeprazole<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">Gi\u1ea3m h\u1ea5p thu Itraconazole<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Thu\u1ed1c h\u1ea1 cholesterol nh\u00f3m \u1ee9c ch\u1ebf HMG-CoA reductase<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">T\u0103ng n\u1ed3ng \u0111\u1ed9 trong m\u00e1u<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Thu\u1ed1c ch\u1eb9n calci<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">Ph\u00f9, \u00f9 tai<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Phenytoin, Phenobarbital, Isoniazid, Rifampicin<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Itraconazole<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Digoxin<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">T\u0103ng n\u1ed3ng \u0111\u1ed9 trong m\u00e1u<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.3102%;\"><span style=\"font-weight: 400;\">Cisaprid, Astemizol, Terfenadin<\/span><\/td>\n<td style=\"width: 48.6052%;\"><span style=\"font-weight: 400;\">T\u0103ng n\u1ed3ng \u0111\u1ed9 trong m\u00e1u<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400;\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng thu\u1ed1c Murkars cho hai \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u t\u01b0\u01a1ng t\u1ef1 c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n, c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng than ho\u1ea1t ho\u1eb7c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 \u0111\u1ec3 x\u1eed tr\u00ed<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Thu\u1ed1c Murkars gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c Murkars hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Murkars t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Murkars nh\u01b0:\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c <\/span><a href=\"https:\/\/vnras.com\/drug\/sporal-100mg\/\"><span style=\"font-weight: 400;\">Sporal 100mg<\/span><\/a><span style=\"font-weight: 400;\"> (Itraconazole) \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Olic (Thailand) Limited, gi\u00e1 90.000\u0111\/h\u1ed9p, d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh do n\u1ea5m g\u00e2y ra nh\u01b0: nhi\u1ec5m n\u1ea5m ph\u1ee5 khoa, n\u1ea5m ngo\u00e0i da, lang ben, n\u1ea5m m\u00f3ng, n\u1ea5m to\u00e0n th\u00e2n, v.v.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">T<\/span><a href=\"https:\/\/www.vnras.com\/drug\/itranstad\"><span style=\"font-weight: 400;\">hu\u1ed1c Itranstad<\/span><\/a><span style=\"font-weight: 400;\"> (Itraconazole) do Stada-Vi\u1ec7t Nam s\u1ea3n xu\u1ea5t (gi\u00e1 92.000\u0111\/h\u1ed9p) d\u00f9ng \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh do n\u1ea5m da, m\u00f3ng, \u00e2m \u0111\u1ea1o, mi\u1ec7ng, ph\u1ed5i, v.v. \u1edf ng\u01b0\u1eddi suy gi\u1ea3m mi\u1ec5n d\u1ecbch v\u00e0 kh\u00f4ng suy gi\u1ea3m mi\u1ec5n d\u1ecbch.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Murkars?<\/span><\/h2>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 61.0314%;\"><span style=\"font-weight: 400;\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 38.7996%;\"><span style=\"font-weight: 400;\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 61.0314%;\"><span style=\"font-weight: 400;\">Trong 1 nghi\u00ean c\u1ee9u so s\u00e1nh \u0111\u1ed9 an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a Itraconazole v\u00e0 Miconazole trong \u0111i\u1ec1u tr\u1ecb n\u1ea5m m\u00f3ng cho th\u1ea5y hai thu\u1ed1c \u0111\u1ec1u dung n\u1ea1p t\u1ed1t, kh\u00f4ng \u1ea3nh h\u01b0\u1edfng ch\u1ee9c n\u0103ng gan \u0111\u00e1ng k\u1ec3 nh\u01b0ng Itraconazole hi\u1ec7u qu\u1ea3 h\u01a1n.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Itraconazole l\u00e0 thu\u1ed1c h\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb vi\u00eam m\u0169i d\u1ecb \u1ee9ng do n\u1ea5m hi\u1ec7u qu\u1ea3 h\u01a1n khi s\u1eed d\u1ee5ng tr\u01b0\u1edbc ph\u1eabu thu\u1eadt so v\u1edbi sau ph\u1eabu thu\u1eadt.<\/span><\/td>\n<td style=\"width: 38.7996%;\">M\u1ed9t s\u1ed1 ch\u1ee7ng n\u1ea5m c\u00f3 th\u1ec3 kh\u00e1ng thu\u1ed1c Murkars<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400;\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">K De Beule, J Van Gestel. (N\u0103m 2001). <\/span><i><span style=\"font-weight: 400;\">Pharmacology of itraconazole<\/span><\/i><span style=\"font-weight: 400;\">. Truy c\u1eadp ng\u00e0y 13 th\u00e1ng 5 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11219548\/\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/11219548\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Katharine E Stott, Thuy Le, Thu Nguyen, Sarah Whalley, Jennifer Unsworth, Vo Trieu Ly, Ruwanthi Kolamunnage-Dona, William Hope. (Ng\u00e0y 18 th\u00e1ng 10 n\u0103m 2021). <\/span><i><span style=\"font-weight: 400;\">Population Pharmacokinetics and Pharmacodynamics of Itraconazole for Disseminated Infection Caused by Talaromyces marneffei<\/span><\/i><span style=\"font-weight: 400;\">. Truy c\u1eadp ng\u00e0y 13 th\u00e1ng 5 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34370587\/\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34370587\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Murkars \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh do n\u1ea5m x\u00e2m l\u1ea5n, n\u1ea5m b\u1ec1 m\u1eb7t, n\u1ea5m Candida v\u00e0 d\u1ef1 ph\u00f2ng cho b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao m\u1eafc b\u1ec7nh nhi\u1ec5m n\u1ea5m h\u1ec7 th\u1ed1ng.<\/p>\n","protected":false},"author":490,"featured_media":73436,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-73435","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/73435","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=73435"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/73436"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=73435"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=73435"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=73435"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}