﻿{"id":72641,"date":"2024-05-07T16:04:50","date_gmt":"2024-05-07T09:04:50","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=72641"},"modified":"2025-07-24T13:40:37","modified_gmt":"2025-07-24T06:40:37","slug":"proluton-depot-250mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/proluton-depot-250mg\/","title":{"rendered":"Proluton Depot 250mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m <a href=\"https:\/\/vnras.com\/drug\/proluton-depot-250mg\/\">thu\u1ed1c Proluton Depot 250mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Bayer Schering Pharma, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam.\u00a0<\/b><\/p>\n<p>&nbsp;<\/p>\n<h2><span style=\"font-weight: 400;\">Proluton Depot 250mg l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400;\"><strong>Thu\u1ed1c Proluton Depot 250mg<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Hydroxyprogesterone caproate 250mg<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 \u1ed1ng<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">D\u1ea1ng b\u00e0o ch\u1ebf: Dung d\u1ecbch ti\u00eam<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">S\u0110K: \u0110ang c\u1eadp nh\u1eadt<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 \u1ed1ng<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Xu\u1ea5t x\u1ee9: \u0110\u1ee9c<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Proluton Depot 250mg<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/span><\/h3>\n<p><span style=\"font-weight: 400;\"><strong>Hydroxyprogesterone<\/strong> &#8211; m\u1ed9t d\u1eabn xu\u1ea5t c\u1ee7a 17-\u03b1-hydroxyprogesterone (17-\u03b1-OHP) l\u00e0 s\u1ea3n ph\u1ea9m chuy\u1ec3n h\u00f3a t\u1ef1 nhi\u00ean c\u1ee7a progesterone, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t trong tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn v\u00e0 ho\u00e0ng th\u1ec3. Trong thai k\u1ef3, 17-\u03b1-OHP \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1edfi c\u1ea3 m\u1eb9 v\u00e0 thai nhi, ch\u1ee7 y\u1ebfu \u1edf tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">C\u01a1 ch\u1ebf m\u00e0 progesterone ng\u0103n ng\u1eeba sinh non ch\u01b0a r\u00f5 r\u00e0ng ho\u00e0n to\u00e0n, nh\u01b0ng c\u00f3 th\u1ec3 li\u00ean quan \u0111\u1ebfn:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">T\u00e1c \u0111\u1ed9ng l\u00ean c\u1ed5 t\u1eed cung:<\/span>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">L\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh tho\u00e1i h\u00f3a collagen c\u1ed5 t\u1eed cung, t\u1eeb \u0111\u00f3 gi\u00fap duy tr\u00ec \u0111\u1ed9 d\u00e0i v\u00e0 s\u1ee9c m\u1ea1nh c\u1ee7a c\u1ed5 t\u1eed cung.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Gi\u1ea3m l\u01b0\u1ee3ng m\u1ed9t s\u1ed1 ch\u1ea5t trung gian g\u00e2y vi\u00eam IL-1\u03b2 t\u1ea1i c\u1ed5 t\u1eed cung, gi\u00fap ng\u0103n ng\u1eeba co th\u1eaft t\u1eed cung s\u1edbm.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">T\u00e1c \u0111\u1ed9ng kh\u00e1c:<\/span>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">\u00cdt \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u01a1 t\u1eed cung ho\u1eb7c m\u00e0ng r\u1ee5ng so v\u1edbi progesterone.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 co b\u00f3p t\u1eed cung.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">H\u1ea5p thu:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft thanh \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 3-7 ng\u00e0y ti\u00eam b\u1eafp 1000mg cho ph\u1ee5 n\u1eef kh\u00f4ng mang thai.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Cmax trung b\u00ecnh: 27,8 (5,3) ng\/mL.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Tmax trung b\u00ecnh: 4,6 (1,7) ng\u00e0y.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">N\u1ed3ng \u0111\u1ed9 th\u1ea5p nh\u1ea5t sau 13 tu\u1ea7n ti\u00eam b\u1eafp 1000mg h\u00e0ng tu\u1ea7n: 60,0 (\u00b114) ng\/mL.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ph\u00e2n b\u1ed1:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">G\u1eafn nhi\u1ec1u v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (albumin, globulin g\u1eafn corticosteroid).<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Chuy\u1ec3n h\u00f3a:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Chuy\u1ec3n h\u00f3a b\u1edfi t\u1ebf b\u00e0o gan ng\u01b0\u1eddi qua ph\u1ea3n \u1ee9ng pha I v\u00e0 pha II.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a: sulfat h\u00f3a, glucuronidated, acetylated\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Trung gian ch\u1ee7 y\u1ebfu b\u1edfi CYP3A4 v\u00e0 CYP3A5.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Nh\u00f3m caproate \u0111\u01b0\u1ee3c gi\u1eef l\u1ea1i trong qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Th\u1ea3i tr\u1eeb:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">T\u00bd: 7,8 (\u00b13,0) ng\u00e0y.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Ch\u1ea5t chuy\u1ec3n h\u00f3a li\u00ean h\u1ee3p chi\u1ebfm ph\u1ea7n l\u1edbn.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Sau khi ti\u00eam b\u1eafp cho ph\u1ee5 n\u1eef mang thai (tu\u1ea7n 10-12):<\/span>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">50% qua ph\u00e2n.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">30% qua n\u01b0\u1edbc ti\u1ec3u.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Thu\u1ed1c Proluton Depot 250mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c <strong>Proluton Depot 250mg<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 sinh non \u1edf ph\u1ee5 n\u1eef mang thai \u0111\u01a1n thai c\u00f3 ti\u1ec1n s\u1eed sinh non \u0111\u01a1n thai t\u1ef1 ph\u00e1t, \u0111\u1ec3 c\u1ea3i thi\u1ec7n t\u1ef7 l\u1ec7 ph\u1ee5 n\u1eef sinh con tr\u01b0\u1edbc 37 tu\u1ea7n tu\u1ed5i thai.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Proluton Depot 250mg<\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Li\u1ec1u: Ti\u00eam b\u1eafp 250 mg (1 ml) m\u1ed7i tu\u1ea7n (c\u00e1ch 7 ng\u00e0y) b\u1edfi c\u00e1n b\u1ed9 y t\u1ebf.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">B\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb: Gi\u1eefa tu\u1ea7n th\u1ee9 16, ng\u00e0y th\u1ee9 0 v\u00e0 tu\u1ea7n th\u1ee9 20, ng\u00e0y th\u1ee9 6 c\u1ee7a thai k\u1ef3.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">M\u1ed7i tu\u1ea7n ti\u00eam Proluton Depot m\u1ed9t l\u1ea7n v\u00e0o c\u01a1 b\u1eafp cho \u0111\u1ebfn tu\u1ea7n th\u1ee9 36 + 6 ng\u00e0y c\u1ee7a thai k\u1ef3 (ho\u1eb7c cho \u0111\u1ebfn khi chuy\u1ec3n d\u1ea1, t\u00f9y theo \u0111i\u1ec1u ki\u1ec7n n\u00e0o \u0111\u1ebfn tr\u01b0\u1edbc)<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">C\u1ea7n ki\u1ec3m tra tr\u1ef1c quan c\u00e1c ch\u1ebf ph\u1ea9m thu\u1ed1c ti\u00eam \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o kh\u00f4ng c\u00f3 h\u1ea1t ho\u1eb7c \u0111\u1ed5i m\u00e0u tr\u01b0\u1edbc khi ti\u00eam, kh\u00f4ng s\u1eed d\u1ee5ng n\u1ebfu c\u00f3 h\u1ea1t r\u1eafn ho\u1eb7c dung d\u1ecbch b\u1ecb v\u1ea9n \u0111\u1ee5c.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">H\u01b0\u1edbng d\u1eabn ti\u00eam:<\/span>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">D\u00f9ng b\u00f4ng t\u0103m t\u1ea9m c\u1ed3n lau s\u1ea1ch \u0111\u1ea7u l\u1ecd thu\u1ed1c tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">H\u00fat 1 ml thu\u1ed1c v\u00e0o b\u01a1m ti\u00eam 3ml v\u1edbi kim 18G<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Thay kim b\u1eb1ng kim 21G<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Sau khi l\u00e0m s\u1ea1ch da, ti\u00eam v\u00e0o ph\u1ea7n tr\u00ean ngo\u00e0i c\u1ee7a m\u00f4ng l\u1edbn. Dung d\u1ecbch nh\u1edbt v\u00e0 c\u00f3 d\u1ea7u. N\u00ean ti\u00eam ch\u1eadm (qu\u00e1 m\u1ed9t ph\u00fat ho\u1eb7c l\u00e2u h\u01a1n).<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Ch\u01b0\u1eddm nh\u1eb9 l\u00ean v\u1ecb tr\u00ed ti\u00eam c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3m s\u01b0ng t\u1ea5y, b\u1ea7m, \u0111au nh\u1ee9c<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">B\u1ecf \u0111i b\u1ea5t k\u1ef3 ph\u1ea7n thu\u1ed1c ch\u01b0a s\u1eed d\u1ee5ng n\u00e0o sau 5 tu\u1ea7n k\u1ec3 t\u1eeb l\u1ea7n s\u1eed d\u1ee5ng \u0111\u1ea7u ti\u00ean.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<figure id=\"attachment_72660\" aria-describedby=\"caption-attachment-72660\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-72660 size-full\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/05\/proluton-depot-250mg-9.jpg\" alt=\"Thu\u1ed1c Proluton Depot 250mg\" width=\"1200\" height=\"1200\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/05\/proluton-depot-250mg-9.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/05\/proluton-depot-250mg-9-400x400.jpg 400w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/05\/proluton-depot-250mg-9-800x800.jpg 800w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/05\/proluton-depot-250mg-9-280x280.jpg 280w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/05\/proluton-depot-250mg-9-768x768.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/05\/proluton-depot-250mg-9-350x350.jpg 350w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/05\/proluton-depot-250mg-9-100x100.jpg 100w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-72660\" class=\"wp-caption-text\">C\u00f4ng dung c\u1ee7a thu\u1ed1c Proluton Depot 250mg<\/figcaption><\/figure>\n<h2><span style=\"font-weight: 400;\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Proluton Depot 250mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">B\u1ecb ung th\u01b0 v\u00fa ti\u1ec1m \u1ea9n ho\u1eb7c nghi ng\u1edd<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">B\u1ec7nh gan ho\u1ea1t \u0111\u1ed9ng\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Huy\u1ebft \u00e1p cao kh\u00f4ng th\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Tr\u1ebb em d\u01b0\u1edbi 18 tu\u1ed5i<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">M\u1eafc ho\u1eb7c c\u00f3 ti\u1ec1n s\u1eed t\u1eafc m\u1ea1ch ho\u1eb7c c\u00e1c r\u1ed1i lo\u1ea1n t\u1eafc m\u1ea1ch<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Xu\u1ea5t huy\u1ebft \u00e2m \u0111\u1ea1o b\u1ea5t th\u01b0\u1eddng ch\u01b0a r\u00f5 nguy\u00ean nh\u00e2n (kh\u00f4ng do thai ngh\u00e9n)<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">U gan l\u00e0nh\/\u00e1c t\u00ednh<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Ung th\u01b0\/ti\u1ec1n s\u1eed ung th\u01b0 nh\u1ea1y c\u1ea3m v\u1edbi hormone kh\u00e1c<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">M\u1eafc b\u1ec7nh v\u00e0ng da do t\u1eafc ngh\u1ebdn h\u1ec7 th\u1ed1ng m\u1eadt trong thai k\u1ef3<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Proluton Depot 250mg<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">R\u1ed1i lo\u1ea1n t\u1eafc m\u1ea1ch: Ng\u1eebng s\u1eed d\u1ee5ng n\u1ebfu c\u00f3 t\u1eafc m\u1ea1ch m\u00e1u s\u00e2u (DVT) ho\u1eb7c t\u1eafc m\u1ea1ch t\u0129nh m\u1ea1ch (PE) ho\u1eb7c c\u00e1c bi\u1ebfn c\u1ed1 t\u1eafc m\u1ea1ch kh\u00e1c.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng: N\u1ebfu c\u00f3 ng\u1ee9a, m\u00e0y \u0111ay, ph\u00f9 m\u1ea1ch n\u00ean ng\u01b0ng d\u00f9ng<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Ph\u1ee5 n\u1eef ti\u1ec1n ti\u1ec3u \u0111\u01b0\u1eddng v\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd do t\u00ecnh tr\u1ea1ng dung n\u1ea1p glucose k\u00e9m<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">L\u01b0u tr\u1eef d\u1ecbch: Theo d\u00f5i ch\u1eb7t ch\u1ebd ph\u1ee5 n\u1eef c\u00f3 nguy c\u01a1 b\u1ecb \u1ea3nh h\u01b0\u1edfng (v\u00ed d\u1ee5: ti\u1ec1n s\u1ea3n gi\u1eadt, \u0111\u1ed9ng kinh, migraine, hen suy\u1ec5n, r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng tim ho\u1eb7c th\u1eadn).<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Vi\u1ec7c theo d\u00f5i ph\u1ee5 n\u1eef c\u00f3 ti\u1ec1n s\u1eed tr\u1ea7m c\u1ea3m l\u00e0 quan tr\u1ecdng \u0111\u1ec3 ph\u00e1t hi\u1ec7n s\u1edbm c\u00e1c d\u1ea5u hi\u1ec7u t\u00e1i ph\u00e1t c\u1ee7a b\u1ec7nh v\u00e0 ng\u01b0ng s\u1eed d\u1ee5ng thu\u1ed1c k\u1ecbp th\u1eddi<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Huy\u1ebft \u00e1p cao, v\u00e0ng da: Theo d\u00f5i ch\u1eb7t ch\u1ebd, c\u00e2n nh\u1eafc l\u1ee3i \u00edch\/nguy c\u01a1 khi ti\u1ebfp t\u1ee5c s\u1eed d\u1ee5ng.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">To\u00e0n th\u00e2n: Ph\u1ea3n \u1ee9ng t\u1ea1i ch\u1ed7 ti\u00eam (bao g\u1ed3m ban \u0111\u1ecf, n\u1ed5i m\u1ec1 \u0111ay, ph\u00e1t ban, k\u00edch \u1ee9ng, qu\u00e1 m\u1eabn, n\u00f3ng r\u00e1t); M\u1ec7t m\u1ecfi; s\u1ed1t; b\u1ed1c h\u1ecfa\/b\u1ed1c h\u1ecfa<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Ti\u00eau h\u00f3a: N\u00f4n m\u1eeda<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Th\u1ea7n kinh r\u1ed1i lo\u1ea1n: \u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Suy c\u1ed5 t\u1eed cung, v\u1ee1 \u1ed1i s\u1edbm<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">R\u1ed1i lo\u1ea1n h\u1ec7 sinh s\u1ea3n v\u00e0 v\u00fa: C\u1ed5 t\u1eed cung gi\u00e3n, c\u1ed5 t\u1eed cung ng\u1eafn l\u1ea1i<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Suy gi\u1ea3m ch\u1ee9c n\u0103ng h\u00f4 h\u1ea5p, t\u1ee9c ng\u1ef1c<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Da: Ph\u00e1t ban<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">\u1ea2nh h\u01b0\u1edfng c\u1ee7a Hydroxyprogesterone caproate l\u00ean enzym Cytochrome P450 (CYP)<\/span><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 53.7676%; text-align: center;\"><span style=\"font-weight: 400;\">CYP<\/span><\/td>\n<td style=\"width: 46.1047%; text-align: center;\"><span style=\"font-weight: 400;\">T\u00e1c \u0111\u1ed9ng<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 53.7676%; text-align: center;\"><span style=\"font-weight: 400;\">CYP1A2, CYP2A6, CYP2B6<\/span><\/td>\n<td style=\"width: 46.1047%; text-align: center;\"><span style=\"font-weight: 400;\">T\u0103ng t\u1ed1c \u0111\u1ed9 chuy\u1ec3n h\u00f3a (80%, 150%, 80%) in vitro<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 53.7676%; text-align: center;\"><span style=\"font-weight: 400;\">CYP1A2, CYP2A6, CYP2B6<\/span><\/td>\n<td style=\"width: 46.1047%; text-align: center;\"><span style=\"font-weight: 400;\">Kh\u00f4ng g\u00e2y c\u1ea3m \u1ee9ng ho\u1eb7c \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng in vitro<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 53.7676%; text-align: center;\"><span style=\"font-weight: 400;\">CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4<\/span><\/td>\n<td style=\"width: 46.1047%; text-align: center;\"><span style=\"font-weight: 400;\">Kh\u00f4ng \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng in vitro<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400;\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Mang thai:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 <strong>Proluton Depot<\/strong> trong 3 th\u00e1ng \u0111\u1ea7u<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">D\u1eef li\u1ec7u cho th\u1ea5y Proluton Depot an to\u00e0n cho thai nhi trong 3 th\u00e1ng gi\u1eefa v\u00e0 cu\u1ed1i thai k\u1ef3.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">An to\u00e0n cho tr\u1ebb s\u01a1 sinh.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Cho con b\u00fa:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">D\u1eebng Proluton Depot \u1edf tu\u1ea7n th\u1ee9 37 c\u1ee7a thai k\u1ef3 ho\u1eb7c sau khi sinh.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Hydroxyprogesterone caproate c\u00f3 th\u1ec3 ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn tr\u1ebb s\u01a1 sinh.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng, kh\u00f4ng c\u00f3 b\u00e1o c\u00e1o n\u00e0o v\u1ec1 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 li\u00ean quan \u0111\u1ebfn vi\u1ec7c d\u00f9ng Proluton Depot qu\u00e1 li\u1ec1u. Trong tr\u01b0\u1eddng h\u1ee3p d\u00f9ng qu\u00e1 li\u1ec1u, c\u1ea7n \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng cho b\u1ec7nh nh\u00e2n.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Thu\u1ed1c Proluton Depot 250mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c Proluton Depot 250mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Proluton Depot 250mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Proluton Depot 250mg nh\u01b0:\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c <\/span><a href=\"https:\/\/vnras.com\/drug\/perfeclly-400mg\/\"><span style=\"font-weight: 400;\">Perfeclly 400mg<\/span><\/a><span style=\"font-weight: 400;\"> (Progesterone 400mg) do FARMAPRIM LTD s\u1ea3n xu\u1ea5t, 650.000\u0111\/h\u1ed9p h\u1ed7 tr\u1ee3 ph\u1ee5 n\u1eef d\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb s\u1ea3y thai, hi\u1ebfm mu\u1ed9n, h\u1ed9i ch\u1ee9ng ti\u1ec1n kinh nguy\u1ec7t.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">T<\/span><a href=\"https:\/\/www.vnras.com\/drug\/duphaston\"><span style=\"font-weight: 400;\">hu\u1ed1c Duphaston<\/span><\/a><span style=\"font-weight: 400;\"> c\u1ee7a Solvay Pharm B.V-H\u00e0 Lan (gi\u00e1 240.000\u0111\/h\u1ed9p) b\u1ed5 sung progesterone cho ph\u1ee5 n\u1eef thi\u1ebfu h\u1ee5t do nguy\u00ean nh\u00e2n t\u1ef1 nhi\u00ean ho\u1eb7c ph\u1eabu thu\u1eadt, \u0111i\u1ec1u tr\u1ecb \u0111au kinh, v\u00f4 kinh, kinh nguy\u1ec7t kh\u00f4ng \u0111\u1ec1u, s\u1ea3y thai\/d\u1ecda s\u1ea3y thai\/v\u00f4 sinh do thi\u1ebfu progesterone\/suy ho\u00e0ng th\u1ec3<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Proluton Depot 250mg?<\/span><\/h2>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 49.9361%; text-align: center;\"><span style=\"font-weight: 400;\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 49.9361%; text-align: center;\"><span style=\"font-weight: 400;\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.9361%;\"><span style=\"font-weight: 400;\">Proluton Depot 250mg \u0111\u01b0\u1ee3c ch\u1ee9ng minh hi\u1ec7u qu\u1ea3 trong vi\u1ec7c gi\u1ea3m nguy c\u01a1 sinh non \u1edf ph\u1ee5 n\u1eef c\u00f3 ti\u1ec1n s\u1eed sinh non \u0111\u01a1n thai.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">M\u1ed7i li\u1ec1u ti\u00eam c\u00f3 t\u00e1c d\u1ee5ng k\u00e9o d\u00e0i m\u1ed9t tu\u1ea7n, gi\u00fap gi\u1ea3m b\u1edbt g\u00e1nh n\u1eb7ng cho b\u1ec7nh nh\u00e2n.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Thu\u1ed1c kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn thai nhi<\/span><\/td>\n<td style=\"width: 49.9361%;\"><span style=\"font-weight: 400;\">C\u1ea7n ph\u1ea3i \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi c\u00e1c c\u00e1n b\u1ed9 y t\u1ebf c\u00f3 chuy\u00ean m\u00f4n, th\u01b0\u1eddng g\u00e2y \u0111au t\u1ea1i ch\u1ed7 ti\u00eam.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400;\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Errol R Norwitz, Aaron B Caughey. (N\u0103m 2011). <\/span><i><span style=\"font-weight: 400;\">Progesterone supplementation and the prevention of preterm birth<\/span><\/i><span style=\"font-weight: 400;\">. Truy c\u1eadp ng\u00e0y 7 th\u00e1ng 5 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22102929\/\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/22102929\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Simi Gupta, Ashley S Roman. (Th\u00e1ng 1 n\u0103m 2012). <\/span><i><span style=\"font-weight: 400;\">17-\u03b1 hydroxyprogesterone caproate for the prevention of preterm birth<\/span><\/i><span style=\"font-weight: 400;\">. Truy c\u1eadp ng\u00e0y 7 th\u00e1ng 5 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22171770\/\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/22171770\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Proluton Depot 250mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 sinh non \u1edf ph\u1ee5 n\u1eef mang thai \u0111\u01a1n thai c\u00f3 ti\u1ec1n s\u1eed sinh non \u0111\u01a1n thai t\u1ef1 ph\u00e1t<\/p>\n","protected":false},"author":1,"featured_media":98510,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-72641","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/72641","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=72641"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/98510"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=72641"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=72641"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=72641"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}