﻿{"id":70024,"date":"2024-04-01T17:25:47","date_gmt":"2024-04-01T10:25:47","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=70024"},"modified":"2025-07-24T13:40:56","modified_gmt":"2025-07-24T06:40:56","slug":"lamzitrio","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/lamzitrio\/","title":{"rendered":"Lamzitrio"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m <a href=\"https:\/\/vnras.com\/drug\/lamzitrio\/\">thu\u1ed1c Lamzitrio<\/a> \u0111i\u1ec1u tr\u1ecb HIV-1 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Stellapharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-31398-18<\/b><\/p>\n<p>&nbsp;<\/p>\n<h2><span style=\"font-weight: 400\">Lamzitrio l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><b>Thu\u1ed1c Lamzitrio<\/b><span style=\"font-weight: 400\"> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Lamivudine: 150 mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nevirapine: 200 mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Zidovudine: 300 mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VD-31398-18<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 10 vi\u00ean<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Lamzitrio<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Lamivudine v\u00e0 Zidovudine:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Thu\u1ed9c nh\u00f3m thu\u1ed1c t\u01b0\u01a1ng t\u1ef1 nucleoside.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a th\u00e0nh Lamivudine 5&#8217;\u2013triphosphate v\u00e0 Zidovudine triphosphate.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a virus b\u1eb1ng c\u00e1ch k\u1ebft th\u00fac chu\u1ed7i phi\u00ean m\u00e3 ng\u01b0\u1ee3c c\u1ee7a virus.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u00f3 t\u00e1c d\u1ee5ng ph\u1ed1i h\u1ee3p m\u1ea1nh m\u1ebd ch\u1ed1ng l\u1ea1i c\u00e1c ch\u1ee7ng HIV trong nu\u00f4i c\u1ea5y t\u1ebf b\u00e0o.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u00f3 th\u1ec3 s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng retrovirus kh\u00e1c m\u00e0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 c\u1ee7a nhau.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Nevirapine:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u1ee8c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a DNA polymerase b\u1eb1ng c\u00e1chg\u1eafn v\u00e0o enzyme phi\u00ean m\u00e3 ng\u01b0\u1ee3c\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ho\u1ea1t \u0111\u1ed9ng kh\u00f4ng c\u1ea1nh tranh v\u1edbi khu\u00f4n m\u1eabu ho\u1eb7c nucleoside triphosphate.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ch\u1ec9 \u1ee9c ch\u1ebf men sao ch\u00e9p ng\u01b0\u1ee3c HIV-1 v\u00e0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn HIV-2 v\u00e0 DNA polymerase \u1edf sinh v\u1eadt nh\u00e2n chu\u1ea9n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng virus trong nu\u00f4i c\u1ea5y t\u1ebf b\u00e0o \u0111\u1ed1i v\u1edbi c\u00e1c ch\u1ee7ng HIV-1 nh\u00f3m O ho\u1eb7c c\u00e1c ch\u1ee7ng HIV-2.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 11.1035%;text-align: center\"><span style=\"font-weight: 400\">Thu\u1ed1c<\/span><\/td>\n<td style=\"width: 16.7707%;text-align: center\"><span style=\"font-weight: 400\">H\u1ea5p thu<\/span><\/td>\n<td style=\"width: 20.9139%;text-align: center\"><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1<\/span><\/td>\n<td style=\"width: 20.2554%;text-align: center\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a<\/span><\/td>\n<td style=\"width: 30.7826%;text-align: center\"><span style=\"font-weight: 400\">Th\u1ea3i tr\u1eeb<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 11.1035%\"><span style=\"font-weight: 400\">Lamivudine<\/span><\/td>\n<td style=\"width: 16.7707%\"><span style=\"font-weight: 400\">Nhanh ch\u00f3ng, ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i<\/span><\/td>\n<td style=\"width: 20.9139%\"><span style=\"font-weight: 400\">Li\u00ean k\u1ebft protein huy\u1ebft t\u01b0\u01a1ng th\u1ea5p<\/span><\/td>\n<td style=\"width: 20.2554%\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a \u00edt<\/span><\/td>\n<td style=\"width: 30.7826%\"><span style=\"font-weight: 400\">Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 11.1035%\"><span style=\"font-weight: 400\">Nevirapine<\/span><\/td>\n<td style=\"width: 16.7707%\"><span style=\"font-weight: 400\">D\u1ec5 d\u00e0ng (&gt;90%)<\/span><\/td>\n<td style=\"width: 20.9139%\"><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i, qua nhau thai v\u00e0 s\u1eefa m\u1eb9<\/span><\/td>\n<td style=\"width: 20.2554%\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a qua cytochrome P450<\/span><\/td>\n<td style=\"width: 30.7826%\"><span style=\"font-weight: 400\">Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng li\u00ean h\u1ee3p glucuronide<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 11.1035%\"><span style=\"font-weight: 400\">Zidovudine<\/span><\/td>\n<td style=\"width: 16.7707%\"><span style=\"font-weight: 400\">Nhanh ch\u00f3ng, ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i<\/span><\/td>\n<td style=\"width: 20.9139%\"><span style=\"font-weight: 400\">Li\u00ean k\u1ebft protein huy\u1ebft t\u01b0\u01a1ng th\u1ea5p<\/span><\/td>\n<td style=\"width: 20.2554%\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan<\/span><\/td>\n<td style=\"width: 30.7826%\"><span style=\"font-weight: 400\">Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng zidovudine v\u00e0 3\u2032-azido-3\u2032-deoxy-5\u2032-O-\u03b2-D-glucopyranuronosylthymidine (GZDV)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Lamzitrio \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c<\/span><b> Lamzitrio<\/b><span style=\"font-weight: 400\"> \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n HIV-1 t\u1eeb 16 tu\u1ed5i tr\u1edf l\u00ean ho\u1eb7c n\u1eb7ng t\u1eeb 50kg.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Lamzitrio Stella<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">U\u1ed1ng thu\u1ed1c <\/span><b>Lamzitrio Stella<\/b><span style=\"font-weight: 400\"> 2 vi\u00ean m\u1ed7i ng\u00e0y chia l\u00e0m 2 l\u1ea7n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u1ebfu b\u1ea1n suy gan n\u1eb7ng ho\u1eb7c gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn, kh\u00f4ng d\u00f9ng Lamzitrio.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u1ebfu b\u1ea1n suy gan nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh, kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u Lamzitrio.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">C\u00e1ch d\u00f9ng<\/span><\/p>\n<p><span style=\"font-weight: 400\">U\u1ed1ng Lamzitrio v\u1edbi n\u01b0\u1edbc.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Lamzitrio kh\u00f4ng b\u1ecb th\u1ee9c \u0103n \u1ea3nh h\u01b0\u1edfng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng Lamzitrio, ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n ho\u00e0n th\u00e0nh 1 th\u00e1ng r\u01b0\u1ee1i &#8211; 2 th\u00e1ng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c lo\u1ea1i thu\u1ed1c \u0111\u01a1n l\u1ebb v\u00e0 \u0111\u1ea1t k\u1ebft qu\u1ea3 t\u00edch c\u1ef1c v\u1edbi Nevirapine 200mg x 2 l\u1ea7n\/ng\u00e0y.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Lamzitrio trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">D\u1ecb \u1ee9ng v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c Lamzitrio.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Suy gi\u1ea3m ch\u1ee9c n\u0103ng gan n\u1eb7ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n c\u00f3 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u trung t\u00ednh th\u1ea5p (&lt; 0,75 x 109\/l) ho\u1eb7c n\u1ed3ng \u0111\u1ed9 hemoglobin th\u1ea5p (&lt; 7,5 g\/dl ho\u1eb7c 4,65 mmol\/l).<\/span><\/p>\n<p><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed ph\u00e1t ban n\u1eb7ng, ph\u00e1t ban k\u00e8m theo c\u00e1c tri\u1ec7u ch\u1ee9ng v\u1ec1 c\u01a1 \u0111\u1ecba ho\u1eb7c nhi\u1ec5m \u0111\u1ed9c gan do nevirapine.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Lamzitrio<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Quan s\u00e1t:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">M\u1ee1 m\u00e1u v\u00e0 \u0111\u01b0\u1eddng huy\u1ebft.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ea3n \u1ee9ng da v\u00e0 t\u1ed5n th\u01b0\u01a1ng gan trong 18 tu\u1ea7n \u0111\u1ea7u (c\u1ea9n th\u1eadn h\u01a1n trong 42 ng\u00e0y \u0111\u1ea7u).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ho\u1ea1t \u0111\u1ed9ng gan v\u00e0 d\u1ea5u hi\u1ec7u nh\u00e2n l\u00ean c\u1ee7a virus vi\u00eam gan B \u1edf b\u1ec7nh nh\u00e2n ng\u01b0ng s\u1eed d\u1ee5ng Lamzitrio v\u00e0 \u0111\u1ed3ng nhi\u1ec5m virus vi\u00eam gan B.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Men gan n\u1ebfu nghi ng\u1edd t\u1ed5n th\u01b0\u01a1ng gan (da v\u00e0ng, ph\u00e2n nh\u1ea1t, bi\u1ebfng \u0103n, bu\u1ed3n n\u00f4n, n\u01b0\u1edbc ti\u1ec3u c\u00f3 bilirubin, gan t\u0103ng k\u00edch th\u01b0\u1edbc\/m\u1ec1m).<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">C\u00e2n nh\u1eafc s\u1eed d\u1ee5ng tr\u00ean:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Gan to ho\u1eb7c c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 gan.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u1eef c\u00f3 CD4+ &lt; 250 t\u1ebf b\u00e0o\/microlit, nam c\u00f3 CD4+ &gt; 400 t\u1ebf b\u00e0o\/microlit, ho\u1eb7c \u0111\u1ed3ng nhi\u1ec5m vi\u00eam gan B\/C m\u1ea1n t\u00ednh.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Suy gan v\u1eeba.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Suy t\u1ee7y ho\u1eb7c thi\u1ebfu m\u00e1u<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1eebng thu\u1ed1c Lamzitrio n\u1ebfu:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">B\u1ea5t th\u01b0\u1eddng trong bi\u1ec3u hi\u1ec7n ho\u1eb7c k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m li\u00ean quan \u0111\u1ebfn vi\u00eam t\u1ee5y.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng ti\u1ebfn tri\u1ec3n, n\u00f4n, ho\u1eb7c x\u00e9t nghi\u1ec7m kh\u00f4ng b\u00ecnh th\u01b0\u1eddng cho \u0111\u1ebfn khi x\u00e1c \u0111\u1ecbnh kh\u00f4ng do vi\u00eam t\u1ee5y.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u00e1c bi\u1ec3u hi\u1ec7n vi\u00eam c\u1ee7a h\u1ed9i ch\u1ee9ng ph\u1ee5c h\u1ed3i mi\u1ec5n d\u1ecbch c\u1ea7n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n v\u00e0 x\u1eed tr\u00ed k\u1ecbp th\u1eddi.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ho\u1ea1i t\u1eed x\u01b0\u01a1ng: Ng\u01b0\u1eddi b\u1ec7nh n\u00ean \u0111i kh\u00e1m n\u1ebfu h\u1ecd b\u1ecb ho\u1ea1i t\u1eed x\u01b0\u01a1ng v\u00e0 c\u00f3 c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 c\u1ee9ng kh\u1edbp, \u0111au\/nh\u1ee9c kh\u1edbp ho\u1eb7c kh\u00f3 v\u1eadn \u0111\u1ed9ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u1ed5i m\u1ea9n n\u1eb7ng, \u0111i k\u00e8m tri\u1ec7u ch\u1ee9ng to\u00e0n th\u00e2n (b\u1ea5t \u1ed5n chung, \u0111au c\u01a1\/kh\u1edbp, l\u1edf mi\u1ec7ng, s\u01b0ng m\u1eb7t, r\u1ed9p da, s\u1ed1t, vi\u00eam k\u1ebft m\u1ea1c), d\u1ecb \u1ee9ng ho\u1eb7c vi\u00eam gan l\u00e2m s\u00e0ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u0103ng men gan \u0111\u1ed9t ng\u1ed9t, gan to ti\u1ebfn tri\u1ec3n, nhi\u1ec5m toan chuy\u1ec3n h\u00f3a\/lactic ch\u01b0a r\u00f5 nguy\u00ean nh\u00e2n.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Th\u01b0\u1eddng g\u1eb7p<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng v\u00e0 \u1ec9a ch\u1ea3y<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">D\u1ecb \u1ee9ng, b\u1ef1c b\u1ed9i, m\u1ec7t m\u1ecfi.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, kh\u00f4ng ng\u1ee7 \u0111\u01b0\u1ee3c<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110au nh\u1ee9c c\u01a1 b\u1eafp<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u1ed5i m\u1ea9n (n\u1eb7ng), r\u1ee5ng t\u00f3c;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Phosphatase ki\u1ec1m v\u00e0 bilirubin, t\u0103ng men gan, vi\u00eam gan<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Thi\u1ebfu m\u00e1u, gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng NEU, gi\u1ea3m WBC<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 16.2362%;text-align: center\"><span style=\"font-weight: 400\">Thu\u1ed1c<\/span><\/td>\n<td style=\"width: 26.4207%;text-align: center\"><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c v\u1edbi<\/span><\/td>\n<td style=\"width: 29.0037%;text-align: center\"><span style=\"font-weight: 400\">\u1ea2nh h\u01b0\u1edfng<\/span><\/td>\n<td style=\"width: 28.3395%;text-align: center\"><span style=\"font-weight: 400\">Khuy\u1ebfn c\u00e1o<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.2362%\"><span style=\"font-weight: 400\">Lamivudine\/Zidovudine<\/span><\/td>\n<td style=\"width: 26.4207%\"><span style=\"font-weight: 400\">Trimethoprim\/Sulfamethoxazole<\/span><\/td>\n<td style=\"width: 29.0037%\"><span style=\"font-weight: 400\">T\u0103ng n\u1ed3ng \u0111\u1ed9 Lamivudine<\/span><\/td>\n<td style=\"width: 28.3395%\"><span style=\"font-weight: 400\">Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 li\u1ec1u cao<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.2362%\"><span style=\"font-weight: 400\">Lamivudine\/Zidovudine<\/span><\/td>\n<td style=\"width: 26.4207%\"><span style=\"font-weight: 400\">Zalcitabine<\/span><\/td>\n<td style=\"width: 29.0037%\"><span style=\"font-weight: 400\">\u1ee8c ch\u1ebf phosphoryl h\u00f3a<\/span><\/td>\n<td style=\"width: 28.3395%\"><span style=\"font-weight: 400\">Kh\u00f4ng n\u00ean d\u00f9ng chung<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.2362%\"><span style=\"font-weight: 400\">Lamivudine\/Zidovudine<\/span><\/td>\n<td style=\"width: 26.4207%\"><span style=\"font-weight: 400\">Stavudine<\/span><\/td>\n<td style=\"width: 29.0037%\"><span style=\"font-weight: 400\">\u0110\u1ed1i kh\u00e1ng v\u1edbi Zidovudine<\/span><\/td>\n<td style=\"width: 28.3395%\"><span style=\"font-weight: 400\">Tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.2362%\"><span style=\"font-weight: 400\">Lamivudine\/Zidovudine<\/span><\/td>\n<td style=\"width: 26.4207%\"><span style=\"font-weight: 400\">Doxorubicin, ribavirin<\/span><\/td>\n<td style=\"width: 29.0037%\"><span style=\"font-weight: 400\">\u0110\u1ed1i kh\u00e1ng v\u1edbi Zidovudine<\/span><\/td>\n<td style=\"width: 28.3395%\"><span style=\"font-weight: 400\">Tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.2362%\"><span style=\"font-weight: 400\">Nevirapine<\/span><\/td>\n<td style=\"width: 26.4207%\"><span style=\"font-weight: 400\">C\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a qua CYP450<\/span><\/td>\n<td style=\"width: 29.0037%\"><span style=\"font-weight: 400\">N\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng th\u1ea5p h\u01a1n<\/span><\/td>\n<td style=\"width: 28.3395%\"><span style=\"font-weight: 400\">Theo d\u00f5i l\u00e2m s\u00e0ng, \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.2362%\"><span style=\"font-weight: 400\">Nevirapine<\/span><\/td>\n<td style=\"width: 26.4207%\"><span style=\"font-weight: 400\">Warfarin<\/span><\/td>\n<td style=\"width: 29.0037%\"><span style=\"font-weight: 400\">Thay \u0111\u1ed5i n\u1ed3ng \u0111\u1ed9 Warfarin<\/span><\/td>\n<td style=\"width: 28.3395%\"><span style=\"font-weight: 400\">Theo d\u00f5i m\u1ee9c \u0111\u1ed9 ch\u1ed1ng \u0111\u00f4ng m\u00e1u<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.2362%\"><span style=\"font-weight: 400\">Zidovudine<\/span><\/td>\n<td style=\"width: 26.4207%\"><span style=\"font-weight: 400\">Ganciclovir, INF-\u03b1, thu\u1ed1c \u1ee9c ch\u1ebf t\u1ee7y x\u01b0\u01a1ng<\/span><\/td>\n<td style=\"width: 29.0037%\"><span style=\"font-weight: 400\">T\u0103ng \u0111\u1ed9c t\u00ednh v\u1ec1 huy\u1ebft h\u1ecdc<\/span><\/td>\n<td style=\"width: 28.3395%\"><span style=\"font-weight: 400\">Tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/span><\/h3>\n<p><span style=\"font-weight: 400\">C\u00e2n nh\u1eafc l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 khi d\u00f9ng Lamzitrio cho hai \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 5.75646%;text-align: center\"><span style=\"font-weight: 400\">Thu\u1ed1c<\/span><\/td>\n<td style=\"width: 9.29889%;text-align: center\"><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u<\/span><\/td>\n<td style=\"width: 58.7454%;text-align: center\"><span style=\"font-weight: 400\">Bi\u1ec3u hi\u1ec7n<\/span><\/td>\n<td style=\"width: 26.1255%;text-align: center\"><span style=\"font-weight: 400\">X\u1eed tr\u00ed<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 5.75646%\"><span style=\"font-weight: 400\">Lamivudine<\/span><\/td>\n<td style=\"width: 9.29889%\"><span style=\"font-weight: 400\">6g<\/span><\/td>\n<td style=\"width: 58.7454%\"><span style=\"font-weight: 400\">Kh\u00f4ng c\u00f3 d\u1ea5u hi\u1ec7u ho\u1eb7c tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng<\/span><\/td>\n<td style=\"width: 26.1255%\"><span style=\"font-weight: 400\">Th\u1ea9m ph\u00e2n m\u00e1u li\u00ean t\u1ee5c c\u00f3 th\u1ec3 kh\u00f4ng mang l\u1ea1i l\u1ee3i \u00edch<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 5.75646%\"><span style=\"font-weight: 400\">Nevirapine<\/span><\/td>\n<td style=\"width: 9.29889%\"><span style=\"font-weight: 400\">800-1800mg\/ng\u00e0y<\/span><\/td>\n<td style=\"width: 58.7454%\"><span style=\"font-weight: 400\">Th\u00e2m nhi\u1ec5m ph\u1ed5i, m\u1ec7t m\u1ecfi, nh\u1ee9c \u0111\u1ea7u, m\u1ea5t ng\u1ee7, bu\u1ed3n n\u00f4n, ch\u00f3ng m\u1eb7t, n\u00f4n m\u1eeda, gi\u1ea3m c\u00e2n, s\u1ed1t, ph\u00f9 n\u1ec1, ban \u0111\u1ecf, ph\u00e1t ban.<\/span><\/td>\n<td style=\"width: 26.1255%\"><span style=\"font-weight: 400\">Ng\u1eebng Nevirapine<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 5.75646%\"><span style=\"font-weight: 400\">Zidovudine<\/span><\/td>\n<td style=\"width: 9.29889%\"><span style=\"font-weight: 400\">50g<\/span><\/td>\n<td style=\"width: 58.7454%\"><span style=\"font-weight: 400\">Bu\u1ed3n m\u1eeda, \u00f3i m\u1eeda, nh\u1ee9c \u0111\u1ea7u, hoa m\u1eaft, cho\u00e1ng v\u00e1ng, l\u01a1 m\u01a1, l\u00e3nh \u0111\u1ea1m, l\u1eabn l\u1ed9n, co gi\u1eadt<\/span><\/td>\n<td style=\"width: 26.1255%\"><span style=\"font-weight: 400\">H\u1ed7 tr\u1ee3<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Lamzitrio gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Lamzitrio hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Lamzitrio t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Lamzitrio nh\u01b0:\u00a0\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Thu\u1ed1c <\/span><a href=\"https:\/\/www.vnras.com\/drug\/zidovudin-stada-300-mg\"><span style=\"font-weight: 400\">Zoquine 300<\/span><\/a><span style=\"font-weight: 400\">, s\u1ea3n xu\u1ea5t t\u1ea1i Vi\u1ec7t Nam b\u1edfi Stada, gi\u00e1 480.000\u0111\/h\u1ed9p, l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb HIV cho ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh v\u00e0 tr\u1ebb em tr\u00ean 12 tu\u1ed5i, gi\u00fap t\u0103ng c\u01b0\u1eddng mi\u1ec5n d\u1ecbch v\u1edbi th\u00e0nh ph\u1ea7n ch\u00ednh Zidovudin 300mg\/vi\u00ean.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T<\/span><a href=\"https:\/\/www.vnras.com\/drug\/zeffix\"><span style=\"font-weight: 400\">hu\u1ed1c Zeffix<\/span><\/a><span style=\"font-weight: 400\">, s\u1ea3n xu\u1ea5t b\u1edfi Glaxo Operations UK., Ltd \u2013 ANH, gi\u00e1 910.000\u0111\/h\u1ed9p, c\u00f3 th\u00e0nh ph\u1ea7n Lamivudine gi\u00fap kh\u00e1ng virus vi\u00eam gan B, \u1ee9c ch\u1ebf enzym phi\u00ean m\u00e3 ng\u01b0\u1ee3c HIV v\u00e0 HBV, \u0111\u01b0\u1ee3c d\u00f9ng \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B m\u1ea1n t\u00ednh, ph\u1ed1i h\u1ee3p \u0111i\u1ec1u tr\u1ecb vi\u00eam gan virus, HIV v\u00e0 c\u00e1c tr\u01b0\u1eddng h\u1ee3p men gan cao.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Lamzitrio?<\/span><\/h2>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 49.0775%\"><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 50.8487%\"><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.0775%\"><span style=\"font-weight: 400\">Lamzitrio c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf virus HIV-1 hi\u1ec7u qu\u1ea3, gi\u00fap gi\u1ea3m t\u1ea3i l\u01b0\u1ee3ng virus trong c\u01a1 th\u1ec3 xu\u1ed1ng m\u1ee9c kh\u00f4ng th\u1ec3 ph\u00e1t hi\u1ec7n (d\u01b0\u1edbi 50 b\u1ea3n sao\/ml) v\u00e0 duy tr\u00ec h\u1ec7 mi\u1ec5n d\u1ecbch kh\u1ecfe m\u1ea1nh.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Lamzitrio \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n, d\u1ec5 d\u00e0ng u\u1ed1ng v\u00e0 c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n.<\/span><\/td>\n<td style=\"width: 50.8487%\"><span style=\"font-weight: 400\">Hi\u1ec7n nay, ch\u01b0a c\u00f3 ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa kh\u1ecfi HIV. Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n u\u1ed1ng ARV su\u1ed1t \u0111\u1eddi \u0111\u1ec3 ki\u1ec3m so\u00e1t virus.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">J F Marier, M Dimarco, R Guilbaud, C Dodard, G Morelli, S K Tippabhotla, A K Singla, N R Thudi, T Monif. (Th\u00e1ng 11 n\u0103m 2007). <\/span><i><span style=\"font-weight: 400\">Pharmacokinetics of lamivudine, zidovudine, and nevirapine administered as a fixed-dose combination formulation versus coadministration of the individual products<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 1 th\u00e1ng 4 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17962426\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/17962426\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">P Munderi, A S Walker, C Kityo, A G Babiker, F Ssali, A Reid, J H Darbyshire, H Grosskurth, P Mugyenyi, D M Gibb, C F Gilks; DART\/NORA trial teams. (Th\u00e1ng 5 n\u0103m 2010). <\/span><i><span style=\"font-weight: 400\">Nevirapine\/zidovudine\/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir\/zidovudine\/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 1 th\u00e1ng 4 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20136661\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/20136661\/<\/span><\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Lamzitrio ch\u1ee9a 3 th\u00e0nh ph\u1ea7n Lamivudine, Nevirapine, Zidovudine \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n HIV-1 t\u1eeb 16 tu\u1ed5i tr\u1edf l\u00ean ho\u1eb7c n\u1eb7ng t\u1eeb 50kg<\/p>\n","protected":false},"author":1,"featured_media":70025,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-70024","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/70024","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=70024"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/70025"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=70024"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=70024"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=70024"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}