﻿{"id":68577,"date":"2024-03-14T13:36:30","date_gmt":"2024-03-14T06:36:30","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=68577"},"modified":"2025-07-24T13:41:13","modified_gmt":"2025-07-24T06:41:13","slug":"arastad-20","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/arastad-20\/","title":{"rendered":"Arastad 20"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/arastad-20\/\">Arastad 20<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Stellapharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-17765-12<\/b><\/p>\n<p>&nbsp;<\/p>\n<h2><span style=\"font-weight: 400\">Arastad 20 l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c<strong> Arastad 20<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Leflunomide 20mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VD-17765-12<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Arastad 20<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/span><\/h3>\n<p><span style=\"font-weight: 400\"><strong>Leflunomide<\/strong> l\u00e0 thu\u1ed1c k\u00ecm h\u00e3m h\u1ec7 mi\u1ec5n d\u1ecbch thu\u1ed9c h\u1ecd Isoxazole.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Hi\u1ec7u qu\u1ea3 c\u1ee7a Leflunomide l\u00e0 ng\u0103n ng\u1eeba t\u0103ng sinh v\u00e0 \u1ee9c ch\u1ebf men dihydroorotate dehydrogenase, g\u00f3p ph\u1ea7n t\u1ea1o ra pyrimidine.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Leflunomide c\u00f3 hi\u1ec7u qu\u1ea3 ch\u1ed1ng vi\u00eam, \u0111i\u1ec1u ch\u1ec9nh t\u1ebf b\u00e0o lympho t\u1ef1 mi\u1ec5n v\u00e0 h\u1ed7 tr\u1ee3 h\u1ea1n ch\u1ebf ph\u1ea3n \u1ee9ng t\u1ef1 mi\u1ec5n trong vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf trong \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p ch\u00ednh x\u00e1c c\u1ee7a Leflunomide v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c l\u00e0m r\u00f5.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Leflunomide:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c \u0111\u1ed9ng v\u00e0o chu k\u1ef3 t\u1ebf b\u00e0o, ch\u1eb7n \u0111\u1ee9ng s\u1ef1 l\u00e2y lan c\u1ee7a t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u t\u1ef1 mi\u1ec5n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ng\u0103n ch\u1eb7n hai men l\u00e0 tyrosine kinase v\u00e0 dihydroorotate dehydrogenase.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tham gia v\u00e0o vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh h\u1ec7 mi\u1ec5n d\u1ecbch.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400\">H\u1ea5p thu:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">H\u1ea5p thu Leflunomide t\u1ed1t qua \u0111\u01b0\u1eddng u\u1ed1ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sinh kh\u1ea3 d\u1ee5ng cao (82 &#8211; 95%).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u1ed3ng \u0111\u1ed9 Leflunomide \u0111\u1ea1t \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 1 gi\u1edd &#8211; 1 ng\u00e0y.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">G\u1eafn k\u1ebft protein huy\u1ebft t\u01b0\u01a1ng cao (&gt; 99%).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1 v\u00e0o s\u1eefa m\u1eb9.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a th\u00e0nh teriflunomide, ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh ch\u00ednh.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Th\u1ea3i tr\u1eeb:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">B\u00e0i ti\u1ebft ph\u1ea7n l\u1edbn qua n\u01b0\u1edbc ti\u1ec3u (43%) v\u00e0 ph\u00e2n (48%).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 2 tu\u1ea7n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Cholestyramin ho\u1eb7c than ho\u1ea1t t\u00ednh c\u00f3 th\u1ec3 \u0111\u1ea9y nhanh t\u1ed1c \u0111\u1ed9 \u0111\u00e0o th\u1ea3i.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Arastad 20 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Arastad 20 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ch\u1eefa tr\u1ecb b\u1ec7nh vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p \u0111ang ti\u1ebfn tri\u1ec3n \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110i\u1ec1u tr\u1ecb b\u1ec7nh vi\u00eam kh\u1edbp v\u1ea3y n\u1ebfn \u0111ang ti\u1ebfn tri\u1ec3n \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Arastad 20<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u1edfi \u0111\u1ea7u: 100mg\/ng\u00e0y x 3 ng\u00e0y (c\u00f3 th\u1ec3 b\u1ecf qua li\u1ec1u n\u1ea1p \u0111\u1ec3 gi\u1ea3m t\u00e1c d\u1ee5ng ph\u1ee5).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Duy tr\u00ec:<\/span>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p: 10 &#8211; 20mg\/ng\u00e0y t\u00f9y m\u1ee9c \u0111\u1ed9 b\u1ec7nh.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Vi\u00eam kh\u1edbp v\u1ea3y n\u1ebfn: 20mg\/ng\u00e0y.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn nh\u1eb9 ho\u1eb7c ng\u01b0\u1eddi tr\u00ean 65 tu\u1ed5i.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea7n ki\u1ec3m tra men gan ALT (SGPT) v\u00e0 c\u00f4ng th\u1ee9c m\u00e1u to\u00e0n ph\u1ea7n tr\u01b0\u1edbc khi kh\u1edfi \u0111\u1ea7u tr\u1ecb li\u1ec7u, hai tu\u1ea7n m\u1ed9t l\u1ea7n trong s\u00e1u th\u00e1ng \u0111\u1ea7u ti\u00ean, v\u00e0 t\u00e1m tu\u1ea7n ti\u1ebfp theo.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">C\u00e1ch d\u00f9ng:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">U\u1ed1ng thu\u1ed1c b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o b\u1eefa \u0103n.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Hi\u1ec7u qu\u1ea3:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u01b0\u1eddng xu\u1ea5t hi\u1ec7n sau 4 &#8211; 6 tu\u1ea7n, c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n h\u01a1n sau 4 &#8211; 6 th\u00e1ng.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Arastad 20 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">H\u1ed9i ch\u1ee9ng suy gi\u1ea3m mi\u1ec5n d\u1ecbch n\u1eb7ng (AIDS)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">D\u1ecb \u1ee9ng v\u1edbi leflunomide, teriflunomide (ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh ch\u00ednh) ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c Arastad 20.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">H\u1ea1 protein huy\u1ebft<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef mang thai<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tr\u1ebb em d\u01b0\u1edbi 18 tu\u1ed5i.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ch\u1ee9c n\u0103ng gan suy y\u1ebfu<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Suy t\u1ee7y (gi\u1ea3m s\u1ea3n t\u1ee7y, thi\u1ebfu m\u00e1u do suy t\u1ee7y, gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh, gi\u1ea3m ti\u1ec3u c\u1ea7u).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef nu\u00f4i con b\u1eb1ng s\u1eefa m\u1eb9<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nhi\u1ec5m tr\u00f9ng n\u1eb7ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef kh\u00f4ng s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Suy th\u1eadn t\u1eeb v\u1eeba \u0111\u1ebfn n\u1eb7ng<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef c\u00f3 kh\u1ea3 n\u0103ng th\u1ee5 thai<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Arastad 20<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4ng d\u00f9ng Arastad 20 chung v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng th\u1ea5p kh\u1edbp d\u1ea1ng th\u1ea5p c\u00f3 t\u00e1c h\u1ea1i tr\u00ean gan ho\u1eb7c m\u00e1u (nh\u01b0 methotrexate).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng \u1edf ng\u01b0\u1eddi t\u1eebng b\u1ecb gi\u1ea3m l\u01b0\u1ee3ng h\u1ed3ng c\u1ea7u, gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u, ti\u1ec3u c\u1ea7u, gi\u1ea3m kh\u1ea3 n\u0103ng s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o m\u00e1u c\u1ee7a t\u1ee7y x\u01b0\u01a1ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Theo d\u00f5i ho\u1ea1t \u0111\u1ed9ng c\u1ee7a gan v\u00e0 th\u00e0nh ph\u1ea7n m\u00e1u th\u01b0\u1eddng xuy\u00ean.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ng\u01b0ng s\u1eed d\u1ee5ng Leflunomide n\u1ebfu c\u00f3 ph\u1ea3n \u1ee9ng li\u00ean quan \u0111\u1ebfn h\u1ec7 th\u1ed1ng m\u00e1u n\u1eb7ng n\u1ec1.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng c\u00f9ng l\u00fac Leflunomide v\u1edbi Azathioprine, D-penicillamine, kim lo\u1ea1i v\u00e0ng, thu\u1ed1c tr\u1ecb s\u1ed1t r\u00e9t.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4ng ph\u1ed1i h\u1ee3p chung Leflunomide v\u1edbi Teriflunomide.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng khi thay \u0111\u1ed5i sang m\u1ed9t thu\u1ed1c DMARD kh\u00e1c.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">D\u1eebng Leflunomide n\u1ebfu c\u00f3 lo\u00e9t d\u1ea1 d\u00e0y.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Theo d\u00f5i c\u1ea9n th\u1eadn n\u1ebfu c\u00f3 bi\u1ec3u hi\u1ec7n b\u1ea5t th\u01b0\u1eddng tr\u00ean da v\u00e0 ni\u00eam m\u1ea1c n\u1eb7ng n\u1ec1.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00e1m nghi\u1ec7m lao \u1ea9n tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Leflunomide.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Theo d\u00f5i ho\u1ea1t \u0111\u1ed9ng c\u1ee7a ph\u1ed5i.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng \u1edf ng\u01b0\u1eddi b\u1ec7nh c\u00f3 kh\u1ea3 n\u0103ng x\u1ea3y ra cao b\u1ec7nh l\u00fd \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn d\u00e2y th\u1ea7n kinh ngo\u1ea1i bi\u00ean.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea9n tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao nhi\u1ec5m tr\u00f9ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nam gi\u1edbi c\u1ea7n s\u1eed d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p tr\u00e1nh thai khi s\u1eed d\u1ee5ng Leflunomide.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">X\u00e1c \u0111\u1ecbnh ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i v\u00f4 c\u0103n<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng \u1edf ng\u01b0\u1eddi b\u1ec7nh c\u00f3 b\u1ea5t th\u01b0\u1eddng di truy\u1ec1n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea9n th\u1eadn khi \u0111i\u1ec1u khi\u1ec3n xe c\u1ed9 ho\u1eb7c s\u1eed d\u1ee5ng m\u00e1y m\u00f3c<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Ph\u1ed5 bi\u1ebfn:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Huy\u1ebft \u00e1p t\u0103ng nh\u1eb9<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Vi\u00eam ru\u1ed9t gi\u00e0 (bao g\u1ed3m vi\u00eam \u0111\u1ea1i tr\u00e0ng d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi, vi\u00eam \u0111\u1ea1i tr\u00e0ng do t\u1ebf b\u00e0o lympho, vi\u00eam \u0111\u1ea1i tr\u00e0ng xu\u1ea5t ti\u1ebft)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110i ngo\u00e0i l\u1ecfng, bu\u1ed3n n\u00f4n, n\u00f4n m\u1eeda<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Lo\u00e9t mi\u1ec7ng (v\u00ed d\u1ee5 l\u1edf mi\u1ec7ng, vi\u00eam lo\u00e9t mi\u1ec7ng)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">S\u1ee5t c\u00e2n, u\u1ec3 o\u1ea3i<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110au d\u1ea1 d\u00e0y<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Men gan t\u0103ng<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">M\u1ea5t c\u1ea3m gi\u00e1c ngon mi\u1ec7ng<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">D\u1ecb \u1ee9ng nh\u1eb9<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">R\u1ee5ng t\u00f3c, ch\u00e0m da, m\u1ea9n ng\u1ee9a (bao g\u1ed3m m\u1ea9n \u0111\u1ecf s\u1ea7n s\u00f9i)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ng\u1ee9a ng\u00e1y, da kh\u00f4<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Vi\u00eam bao ho\u1ea1t d\u1ecbch<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00ea b\u00ec, nh\u1ee9c \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, vi\u00eam d\u00e2y th\u1ea7n kinh ngo\u1ea1i bi\u00ean<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%;height: 21px\">\n<tbody>\n<tr>\n<td style=\"width: 44.797%;text-align: center\"><span style=\"font-weight: 400\">Thu\u1ed1c<\/span><\/td>\n<td style=\"width: 55.1292%;text-align: center\"><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 44.797%\"><span style=\"font-weight: 400\">Thu\u1ed1c \u1ee9c ch\u1ebf CYP2C9<\/span><\/td>\n<td style=\"width: 55.1292%\"><span style=\"font-weight: 400\">Thay \u0111\u1ed5i d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a NSAID<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 44.797%\"><span style=\"font-weight: 400\">Thu\u1ed1c \u0111\u1ed9c gan<\/span><\/td>\n<td style=\"width: 55.1292%\"><span style=\"font-weight: 400\">T\u0103ng t\u00e1c d\u1ee5ng ph\u1ee5 gan<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 44.797%\"><span style=\"font-weight: 400\">Methotrexat<\/span><\/td>\n<td style=\"width: 55.1292%\"><span style=\"font-weight: 400\">T\u0103ng enzyme gan<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 44.797%\"><span style=\"font-weight: 400\">Warfarin<\/span><\/td>\n<td style=\"width: 55.1292%\"><span style=\"font-weight: 400\">T\u0103ng INR<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 44.797%\"><span style=\"font-weight: 400\">Cholestyramin, than ho\u1ea1t t\u00ednh<\/span><\/td>\n<td style=\"width: 55.1292%\"><span style=\"font-weight: 400\">Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Leflunomide<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 44.797%\"><span style=\"font-weight: 400\">NSAID<\/span><\/td>\n<td style=\"width: 55.1292%\"><span style=\"font-weight: 400\">T\u0103ng enzyme gan<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 44.797%\"><span style=\"font-weight: 400\">Rifampin<\/span><\/td>\n<td style=\"width: 55.1292%\"><span style=\"font-weight: 400\">T\u0103ng n\u1ed3ng \u0111\u1ed9 Leflunomide<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 44.797%\"><span style=\"font-weight: 400\">Vaccine virus s\u1ed1ng<\/span><\/td>\n<td style=\"width: 55.1292%\"><span style=\"font-weight: 400\">Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Mang thai:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u ho\u00e0n ch\u1ec9nh v\u1ec1 Leflunomide tr\u00ean ph\u1ee5 n\u1eef mang thai.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Leflunomide c\u00f3 th\u1ec3 g\u00e2y s\u1ea3y thai ho\u1eb7c d\u1ecb t\u1eadt b\u1ea9m sinh.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef c\u00f3 th\u1ec3 mang thai ph\u1ea3i s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai an to\u00e0n khi d\u00f9ng Leflunomide.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea7n lo\u1ea1i b\u1ecf Leflunomide kh\u1ecfi c\u01a1 th\u1ec3 tr\u01b0\u1edbc khi mang thai.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Cho con b\u00fa:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u1ea3 n\u0103ng Leflunomide b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 ch\u01b0a \u0111\u01b0\u1ee3c l\u00e0m r\u00f5.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u00e2n nh\u1eafc k\u1ef9 tr\u01b0\u1edbc khi d\u00f9ng Leflunomide n\u1ebfu \u0111ang cho con b\u00fa.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Tri\u1ec7u ch\u1ee9ng:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nhi\u1ec5m \u0111\u1ed9c m\u00e3n t\u00ednh: D\u00f9ng li\u1ec1u cao g\u1ea5p 5 l\u1ea7n khuy\u1ebfn c\u00e1o, c\u00f3 th\u1ec3 kh\u00f4ng xu\u1ea5t hi\u1ec7n b\u1ea5t k\u1ef3 bi\u1ec3u hi\u1ec7n n\u00e0o.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u c\u1ea5p: \u0110au b\u1ee5ng, \u0111i ngo\u00e0i ph\u00e2n l\u1ecfng, thi\u1ebfu m\u00e1u, gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u, men gan t\u0103ng cao.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">X\u1eed tr\u00ed:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">S\u1eed d\u1ee5ng cholestyramine ho\u1eb7c than ho\u1ea1t t\u00ednh \u0111\u1ec3 \u0111\u1ea9y nhanh qu\u00e1 tr\u00ecnh \u0111\u00e0o th\u1ea3i thu\u1ed1c Arastad 20.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh M1 kh\u00f4ng th\u1ec3 lo\u1ea1i b\u1ecf b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p th\u1ea9m t\u00e1ch m\u00e1u.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Arastad 20 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Arastad 20 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Arastad 20. t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Arastad 20 nh\u01b0:\u00a0\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><a href=\"https:\/\/www.vnras.com\/drug\/osbifin-20-mg\"><span style=\"font-weight: 400\">Thu\u1ed1c Osbifin 20mg<\/span><\/a><span style=\"font-weight: 400\"> (Leflunomide) gi\u00e1 770.000\u0111\/h\u1ed9p, s\u1ea3n xu\u1ea5t b\u1edfi Haupt Pharma M\u00fcnster GmbH, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam x\u01b0\u01a1ng kh\u1edbp, vi\u00eam th\u1ea5p kh\u1edbp do r\u1ed1i lo\u1ea1n h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T<\/span><a href=\"https:\/\/www.vnras.com\/drug\/Metrex_tab\"><span style=\"font-weight: 400\">hu\u1ed1c Metrex tab<\/span><\/a><span style=\"font-weight: 400\"> (Methotrexate) gi\u00e1 3.500.000\u0111\/h\u1ed9p, s\u1ea3n xu\u1ea5t b\u1edfi Dae Han New Pharm Co., Ltd \u2013 H\u00c0N QU\u1ed0C, \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01a1n ho\u1eb7c \u0111a tr\u1ecb li\u1ec7u cho b\u1ec7nh nh\u00e2n ung th\u01b0 ho\u1eb7c c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 h\u1ec7 mi\u1ec5n d\u1ecbch.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Arastad 20?<\/span><\/h2>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 51.5867%\"><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 48.3395%\"><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 51.5867%\"><span style=\"font-weight: 400\">Hi\u1ec7u qu\u1ea3 cao trong \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p v\u00e0 vi\u00eam kh\u1edbp v\u1ea3y n\u1ebfn ti\u1ebfn tri\u1ec3n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 \u0111au nh\u1ee9c, s\u01b0ng t\u1ea5y, c\u1ee9ng kh\u1edbp.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng v\u1eadn \u0111\u1ed9ng v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng.<\/span><\/td>\n<td style=\"width: 48.3395%\"><span style=\"font-weight: 400\">M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng Arastad 20 bao g\u1ed3m bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, nh\u1ee9c \u0111\u1ea7u v\u00e0 r\u1ee5ng t\u00f3c.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Roberto Alfaro-Lara, Hector Fabricio Espinosa-Ortega, C\u00e9sar Alejandro Arce-Salinas; PRECIS study group, all physicians belong to Division of Internal Medicine. Hospital Central Sur de Pemexa\u0309. (Th\u00e1ng 5-6 n\u0103m 2019). <\/span><i><span style=\"font-weight: 400\">Systematic review and meta-analysis of the efficacy and safety of leflunomide and methotrexate in the treatment of rheumatoid arthritis<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 14 th\u00e1ng 3 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28867467\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28867467\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kunyu Zheng, Yiran Chen, Suying Liu, Chengmei He, Yunjiao Yang, Di Wu, Li Wang, Mengtao Li, Xiaofeng Zeng, Fengchun Zhang. (Th\u00e1ng 2 n\u0103m 2023). <\/span><i><span style=\"font-weight: 400\">Leflunomide: Traditional immunosuppressant with concurrent antiviral effects<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 14 th\u00e1ng 3 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36371788\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36371788\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Arastad 20 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p \u0111ang ti\u1ebfn tri\u1ec3n \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh v\u00e0 vi\u00eam kh\u1edbp v\u1ea3y n\u1ebfn \u0111ang ti\u1ebfn tri\u1ec3n<\/p>\n","protected":false},"author":1,"featured_media":68579,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-68577","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/68577","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=68577"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/68579"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=68577"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=68577"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=68577"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}