﻿{"id":64477,"date":"2024-01-08T17:44:00","date_gmt":"2024-01-08T10:44:00","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=64477"},"modified":"2025-07-24T13:43:46","modified_gmt":"2025-07-24T06:43:46","slug":"topraz-20","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/topraz-20\/","title":{"rendered":"Topraz 20"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/topraz-20\/\">Topraz 20<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Aurobindo Pharma Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-22990-21<\/b><\/p>\n<p>&nbsp;<\/p>\n<h2><span style=\"font-weight: 400\">Topraz 20 l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\"><strong>Thu\u1ed1c Topraz 20<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n trong 1 vi\u00ean g\u1ed3m:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Pantoprazol (d\u1ea1ng Natri Pantoprazol Sesquihydrat) 20mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c kh\u00e1c v\u1eeba \u0111\u1ee7<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao tan trong ru\u1ed9t<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VN-22990-21<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9<\/span><\/p>\n<p><i><span style=\"font-weight: 400\">S\u1ea3n ph\u1ea9m n\u00e0y kh\u00f4ng ph\u1ea3i l\u00e0 thu\u1ed1c, kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng thay th\u1ebf thu\u1ed1c ch\u1eefa b\u1ec7nh<\/span><\/i><\/p>\n<h2><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Topraz 20<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/span><\/h3>\n<p><span style=\"font-weight: 400\"><strong>Pantoprazol<\/strong> l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf b\u01a1m proton, c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc b\u01a1m proton c\u1ee7a c\u00e1c t\u1ebf b\u00e0o th\u00e0nh d\u1ea1 d\u00e0y. B\u01a1m proton l\u00e0 enzym cu\u1ed1i c\u00f9ng trong qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t acid hydrochloric trong d\u1ea1 d\u00e0y. Khi pantoprazol g\u1eafn v\u00e0o b\u01a1m proton, n\u00f3 s\u1ebd \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t acid hydrochloride, t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 acid trong d\u1ea1 d\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pantoprazol c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf b\u00e0i ti\u1ebft acid hydrochloride c\u1ea3 khi d\u1ea1 d\u00e0y \u1edf tr\u1ea1ng th\u00e1i ngh\u1ec9 (t\u1ee9c l\u00e0 b\u00e0i ti\u1ebft acid c\u01a1 b\u1ea3n) v\u00e0 khi d\u1ea1 d\u00e0y b\u1ecb k\u00edch th\u00edch (t\u1ee9c l\u00e0 b\u00e0i ti\u1ebft acid do c\u00e1c t\u00e1c nh\u00e2n k\u00edch th\u00edch nh\u01b0 th\u1ee9c \u0103n, stress, thu\u1ed1c l\u00e1,&#8230;).<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pantoprazol c\u0169ng c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 gastrin trong m\u00e1u. Tuy nhi\u00ean, s\u1ef1 t\u0103ng n\u1ed3ng \u0111\u1ed9 gastrin n\u00e0y l\u00e0 t\u1ea1m th\u1eddi v\u00e0 kh\u00f4ng g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nguy hi\u1ec3m.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Kh\u1ea3 n\u0103ng h\u1ea5p thu c\u1ee7a Pantoprazol kh\u00e1 nhanh v\u00e0 \u0111\u1ea1t Cmax trong huy\u1ebft t\u01b0\u01a1ng sau 2-2,5 gi\u1edd<\/span><\/p>\n<p><span style=\"font-weight: 400\">Ch\u1ec9 kho\u1ea3ng 2% Pantoprazol kh\u00f4ng li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pantoprazol \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a qua gan g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Kho\u1ea3ng 80% Pantoprazol \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua th\u1eadn, c\u00f2n l\u1ea1i qua ph\u00e2n v\u1edbi T<\/span><span style=\"font-weight: 400\">1\/2<\/span><span style=\"font-weight: 400\"> l\u00e0 1 gi\u1edd.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Topraz 20 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Topraz 20mg \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00e1c bi\u1ec3u hi\u1ec7n c\u1ee7a b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n v\u00e0 ki\u1ec3m so\u00e1t d\u00e0i l\u00e2u v\u00e0 ng\u0103n ch\u1eb7n t\u00e1i ph\u00e1t trong vi\u00eam th\u1ef1c qu\u1ea3n tr\u00e0o ng\u01b0\u1ee3c \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb tr\u00ean 12 tu\u1ed5i.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Topraz 20 c\u0169ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng \u0111\u1ec3 d\u1ef1 ph\u00f2ng lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng g\u00e2y ra do NSAIDs \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 lo\u00e9t m\u00e0 b\u1eaft bu\u1ed9c c\u1ea7n d\u00f9ng c\u00e1c thu\u1ed1c NSAID.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Topraz 20<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng<\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%;height: 550px\">\n<tbody>\n<tr style=\"height: 50px\">\n<td style=\"width: 16.0811%;height: 50px\"><span style=\"font-weight: 400\">\u0110\u1ed1i T\u01b0\u1ee3ng<\/span><\/td>\n<td style=\"width: 31.2162%;height: 50px\"><span style=\"font-weight: 400\">Ch\u1ec9 \u0111\u1ecbnh<\/span><\/td>\n<td style=\"width: 52.5676%;height: 50px\"><span style=\"font-weight: 400\">Li\u1ec1u D\u00f9ng<\/span><\/td>\n<\/tr>\n<tr style=\"height: 122px\">\n<td style=\"width: 16.0811%;height: 229px\" rowspan=\"2\"><span style=\"font-weight: 400\">Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb &gt; 12 tu\u1ed5i<\/span><\/td>\n<td style=\"width: 31.2162%;height: 122px\"><span style=\"font-weight: 400\">\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n<\/span><\/td>\n<td style=\"width: 52.5676%;height: 122px\"><span style=\"font-weight: 400\">1 vi\u00ean\/ng\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u00e1c bi\u1ec3u hi\u1ec7n th\u01b0\u1eddng gi\u1ea3m sau 14-28 ng\u00e0y.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u00f3 th\u1ec3 t\u0103ng th\u00eam 4 tu\u1ea7n n\u1ebfu c\u1ea7n.\u00a0<\/span><\/td>\n<\/tr>\n<tr style=\"height: 107px\">\n<td style=\"width: 31.2162%;height: 107px\"><span style=\"font-weight: 400\">Ph\u00f2ng ng\u1eeba tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n t\u00e1i ph\u00e1t<\/span><\/td>\n<td style=\"width: 52.5676%;height: 107px\"><span style=\"font-weight: 400\">Duy tr\u00ec 1 vi\u00ean\/ng\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p t\u00e1i ph\u00e1t 2 vi\u00ean\/ng\u00e0y sau \u0111\u00f3 gi\u1ea3m li\u1ec1u tr\u1edf l\u1ea1i khi c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111\u00e3 \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t<\/span><\/td>\n<\/tr>\n<tr style=\"height: 71px\">\n<td style=\"width: 16.0811%;height: 71px\"><span style=\"font-weight: 400\">Ng\u01b0\u1eddi l\u1edbn<\/span><\/td>\n<td style=\"width: 31.2162%;height: 71px\"><span style=\"font-weight: 400\">D\u1ef1 ph\u00f2ng lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng do NSAIDs<\/span><\/td>\n<td style=\"width: 52.5676%;height: 71px\"><span style=\"font-weight: 400\">1 vi\u00ean\/ng\u00e0y.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 50px\">\n<td style=\"width: 16.0811%;height: 200px\" rowspan=\"4\"><span style=\"font-weight: 400\">Nh\u00f3m b\u1ec7nh nh\u00e2n \u0111\u1eb7c bi\u1ec7t<\/span><\/td>\n<td style=\"width: 31.2162%;height: 50px\"><span style=\"font-weight: 400\">Suy gan<\/span><\/td>\n<td style=\"width: 52.5676%;height: 50px\"><span style=\"font-weight: 400\">Kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 1 vi\u00ean\/ng\u00e0y \u1edf b\u1ec7nh nh\u00e2n suy gan n\u1eb7ng.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 50px\">\n<td style=\"width: 31.2162%;height: 50px\"><span style=\"font-weight: 400\">Suy th\u1eadn<\/span><\/td>\n<td style=\"width: 52.5676%;height: 50px\"><span style=\"font-weight: 400\">Kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u<\/span><\/td>\n<\/tr>\n<tr style=\"height: 50px\">\n<td style=\"width: 31.2162%;height: 50px\"><span style=\"font-weight: 400\">Ng\u01b0\u1eddi cao tu\u1ed5i<\/span><\/td>\n<td style=\"width: 52.5676%;height: 50px\"><span style=\"font-weight: 400\">Kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u<\/span><\/td>\n<\/tr>\n<tr style=\"height: 50px\">\n<td style=\"width: 31.2162%;height: 50px\"><span style=\"font-weight: 400\">Tr\u1ebb em<\/span><\/td>\n<td style=\"width: 52.5676%;height: 50px\"><span style=\"font-weight: 400\">Kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng Topraz cho tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">C\u00e1ch d\u00f9ng<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u1eed d\u1ee5ng <strong>Topraz 20<\/strong> \u0111\u01b0\u1eddng u\u1ed1ng tr\u01b0\u1edbc b\u1eefa \u0103n 60 ph\u00fat.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">L\u01b0u \u00fd n\u00ean nu\u1ed1t nguy\u00ean vi\u00ean kh\u00f4ng \u0111\u01b0\u1ee3c nhai hay nghi\u1ec1n vi\u00ean thu\u1ed1c.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Topraz 20 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">D\u1ecb \u1ee9ng v\u1edbi Benzimidazol hay b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o kh\u00e1c c\u1ee7a thu\u1ed1c.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Topraz 20<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Trong khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Pantoprazole \u1edf ng\u01b0\u1eddi suy gi\u1ea3m ch\u1ee9c n\u0103ng gan n\u1eb7ng c\u1ea7n theo d\u00f5i c\u00e1c enzyme gan \u0111\u1ecbnh k\u1ef3. D\u1eebng \u0111i\u1ec1u tr\u1ecb n\u1ebfu enzym gan t\u0103ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pantoprazol 20 mg ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ng\u0103n ng\u1eeba lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng b\u1edfi NSAIDs \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao. N\u00ean \u0111\u00e1nh gi\u00e1 nguy c\u01a1 bi\u1ebfn ch\u1ee9ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a d\u1ef1a tr\u00ean c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 c\u00e1 nh\u00e2n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh d\u1ea1 d\u00e0y \u00e1c t\u00ednh c\u00f3 th\u1ec3 b\u1ecb \u1ea9n \u0111i b\u1edfi Pantoprazol v\u00e0 c\u00f3 th\u1ec3 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ea9n \u0111o\u00e1n.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u00e1nh k\u1ebft h\u1ee3p Pantoprazol v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf HIV protease nh\u01b0 atazanavir v\u00ec \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u1ea5p th\u1ee5.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pantoprazol c\u00f3 th\u1ec3 gi\u1ea3m h\u1ea5p th\u1ee5 vitamin B12, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u1ea7n gi\u00e1m s\u00e1t th\u01b0\u1eddng xuy\u00ean, \u0111\u1eb7c bi\u1ec7t khi \u0111i\u1ec1u tr\u1ecb t\u1eeb 1 n\u0103m tr\u1edf l\u00ean.<\/span><\/p>\n<p><span style=\"font-weight: 400\">N\u1ed3ng \u0111\u1ed9 magnesi huy\u1ebft c\u00f3 th\u1ec3 b\u1ecb gi\u1ea3m n\u1eb7ng khi d\u00f9ng Pantoprazol. C\u00e2n nh\u1eafc \u0111o n\u1ed3ng \u0111\u1ed9 magnesi tr\u01b0\u1edbc v\u00e0 trong khi \u0111i\u1ec1u tr\u1ecb, \u0111\u1eb7c bi\u1ec7t \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng l\u00e2u d\u00e0i.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u1ea3nh b\u00e1o v\u1ec1 li\u00ean quan gi\u1eefa Pantoprazol v\u00e0 lupus ban \u0111\u1ecf b\u00e1n c\u1ea5p tr\u00ean da.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pantoprazol c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Chromogranin A, l\u00e0m \u1ea3nh h\u01b0\u1edbng \u0111\u1ebfn ch\u1ea9n \u0111o\u00e1n kh\u1ed1i u th\u1ea7n kinh. D\u1eebng \u0111i\u1ec1u tr\u1ecb Pantoprazol \u00edt nh\u1ea5t 5 ng\u00e0y tr\u01b0\u1edbc khi \u0111o Chromogranin A v\u00e0 gastrin.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/span><\/h3>\n<p><span style=\"font-weight: 400\">C\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u00f3 th\u1ec3 x\u1ea3y ra khi s\u1eed d\u1ee5ng Topraz 20 theo t\u1ea7n su\u1ea5t nh\u01b0:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u01b0\u1eddng g\u1eb7p: Polyp l\u00e0nh t\u00ednh tuy\u1ebfn ti\u1ec1n li\u1ec7t<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u00cdt g\u1eb7p: r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a (n\u00f4ng, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, \u0111\u1ea7y h\u01a1i, t\u00e1o b\u00f3n,&#8230;), ph\u00e1t ban, t\u0103ng men gan,&#8230;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Hi\u1ebfm g\u1eb7p: \u0111au c\u01a1, \u0111au kh\u1edbp, t\u0103ng th\u00e2n nhi\u1ec7t, ph\u00f9 ngo\u1ea1i bi\u00ean, nam gi\u1edbi v\u00fa to, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c,&#8230;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">R\u1ea5t hi\u1ebfm g\u1eb7p: gi\u1ea3m huy\u1ebft c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u, m\u1ea5t \u0111\u1ecbnh h\u01b0\u1edbng<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ch\u01b0a r\u00f5: \u1ea3o gi\u00e1c, l\u00fa l\u1eabn, h\u1ea1 natri huy\u1ebft, h\u1ea1 calci huy\u1ebft, t\u1ed5n th\u01b0\u01a1ng gan&#8230;\u00a0<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u1eed d\u1ee5ng Pantoprazol cho ph\u1ee5 n\u1eef trong thai k\u1ef3 v\u1edbi c\u1ee1 m\u1eabu kho\u1ea3ng 300-1000 ng\u01b0\u1eddi kh\u00f4ng ghi nh\u1eadn d\u1ecb d\u1ea1ng ho\u1eb7c \u0111\u1ed9c t\u00ednh \u0111\u1ed1i v\u1edbi thai nhi\/tr\u1ebb s\u01a1 sinh. Tuy nhi\u00ean, v\u1eabn n\u00ean tr\u00e1nh d\u00f9ng \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n cho tr\u1ebb.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pantoprazol \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n b\u00e0i ti\u1ebft qua s\u1eefa trong c\u00e1c nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt. M\u1eb7c d\u00f9 d\u1eef li\u1ec7u v\u1ec1 l\u01b0\u1ee3ng b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9 \u1edf ng\u01b0\u1eddi l\u00e0 h\u1ea1n ch\u1ebf, nh\u01b0ng \u0111\u00e3 c\u00f3 ghi nh\u1eadn v\u1ec1 s\u1ef1 b\u00e0i ti\u1ebft n\u00e0y. Nguy c\u01a1 \u0111\u1ed1i v\u1edbi tr\u1ebb s\u01a1 sinh\/tr\u1ebb nh\u1ecf kh\u00f4ng th\u1ec3 lo\u1ea1i tr\u1eeb n\u00ean vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c c\u1ea7n c\u00e2n nh\u1eafc th\u1eadt k\u1ef9.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Thu\u1ed1c c\u00f3 d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc h\u1ea5p thu ph\u1ee5 thu\u1ed9c pH: Kh\u1ea3 n\u0103ng h\u1ea5p thu c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 gi\u1ea3m.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Thu\u1ed1c \u1ee9c ch\u1ebf HIV protease: Kh\u00f4ng n\u00ean d\u00f9ng chung Pantoprazol v\u1edbi Atazanavir.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng coumarin: T\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Methotrexat: D\u00f9ng \u0111\u1ed3ng th\u1eddi Pantoprazol v\u1edbi Methotrexat li\u1ec1u cao c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh c\u1ee7a Methotrexat.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Thu\u1ed1c \u1ee9c ch\u1ebf ho\u1eb7c c\u1ea3m \u1ee9ng CYP2C19: C\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u Pantoprazol khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c n\u00e0y.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Hi\u1ec7n t\u01b0\u1ee3ng qu\u00e1 li\u1ec1u ch\u01b0a ghi nh\u1eadn khi s\u1eed d\u1ee5ng Pantoprazol.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Topraz 20 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\"><strong>Thu\u1ed1c Topraz 20mg<\/strong> hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Topraz 20 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Topraz 20 nh\u01b0:\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c <\/span><a href=\"https:\/\/vnras.com\/drug\/panto-denk-20\/\"><span style=\"font-weight: 400\">Panto-Denk 20<\/span><\/a><span style=\"font-weight: 400\"> c\u00f3 gi\u00e1 170.000\u0111\/h\u1ed9p \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Advance Pharma GmbH- \u0110\u1ee9c. Thu\u1ed1c Panto-Denk 20 ch\u1ee9a Pantoprazol 20mg d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh lo\u00e9t d\u1ea1 d\u00e0y, tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n, ph\u00f2ng ng\u1eeba lo\u00e9t d\u1ea1 d\u00e0y g\u00e2y ra b\u1edfi NSAIDs<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c <\/span><a href=\"https:\/\/vnras.com\/drug\/prasocare\/\"><span style=\"font-weight: 400\">Prasocare<\/span><\/a><span style=\"font-weight: 400\"> c\u00f3 gi\u00e1 300.000 \u0111\u1ed3ng\/h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean. Thu\u1ed1c Prasocare \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n, b\u1ec7nh lo\u00e9t d\u1ea1 d\u00e0y, h\u1ed7 tr\u1ee3 trong \u0111i\u1ec1u tr\u1ecb H. pylori, ph\u00f2ng ng\u1eeba ch\u1ea3y m\u00e1u \u0111\u01b0\u1eddng ti\u00eau h\u00f3a do \u0111i\u1ec1u tr\u1ecb d\u00e0i h\u1ea1n c\u00e1c thu\u1ed1c NSAID, \u0111i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng Zollinger-Ellison.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Topraz 20?<\/span><\/h2>\n<table style=\"border-collapse: collapse;width: 100%;height: 23px\">\n<tbody>\n<tr>\n<td style=\"width: 55.4053%;text-align: center\"><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 44.4595%;text-align: center\"><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 55.4053%\"><span style=\"font-weight: 400\">Pantoprazol \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u00e0 m\u1ed9t thu\u1ed1c an to\u00e0n, v\u1edbi t\u1ef7 l\u1ec7 t\u00e1c d\u1ee5ng ph\u1ee5 th\u1ea5p.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean n\u00e9n d\u1ec5 s\u1eed d\u1ee5ng v\u00e0 b\u1ea3o qu\u1ea3n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Gi\u00e1 th\u00e0nh kh\u00e1 ph\u1ea3i ch\u0103ng cho 1 h\u1ed9p 30 vi\u00ean.\u00a0<\/span><\/td>\n<td style=\"width: 44.4595%\">Pantoprazole c\u1ea7n \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng c\u1ea9n th\u1eadn \u1edf b\u1ec7nh nh\u00e2n c\u00f3 suy gan n\u1eb7ng v\u00e0 c\u1ea7n theo d\u00f5i c\u00e1c ch\u1ec9 s\u1ed1 enzym gan \u0111\u1ec1u \u0111\u1eb7n trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Christo J van Rensburg, Susan Cheer . Ng\u00e0y <\/span><span style=\"font-weight: 400\">17 th\u00e1ng 9 n\u0103m 2012<\/span><span style=\"font-weight: 400\">). <\/span><i><span style=\"font-weight: 400\">Pantoprazole for the treatment of peptic ulcer bleeding and prevention of rebleeding<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 8 th\u00e1ng 1 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24833934\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/24833934\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Forough Saki, Mesbah Shams, Sanaz Dastghaib, Farhad Koohpeyma. (Ng\u00e0y 6 th\u00e1ng 9 n\u0103m 2023). <\/span><i><span style=\"font-weight: 400\">Pantoprazole-Induced Bone Loss through Gastrin Secretion: A Stereological Study<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 8 th\u00e1ng 1 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37711876\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37711876\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Topraz 20 ch\u1ee9a Pantoprazol ng\u0103n ch\u1eb7n s\u1ef1 s\u1ea3n xu\u1ea5t acid d\u1ea1 d\u00e0y, t\u1eeb \u0111\u00f3 gi\u00fap c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n<\/p>\n","protected":false},"author":1,"featured_media":64397,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-64477","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/64477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=64477"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/64397"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=64477"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=64477"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=64477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}