﻿{"id":63273,"date":"2023-12-31T12:11:28","date_gmt":"2023-12-31T05:11:28","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=63273"},"modified":"2026-01-18T15:00:46","modified_gmt":"2026-01-18T08:00:46","slug":"pramipexol-normon-018-mg-tablets","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/pramipexol-normon-018-mg-tablets\/","title":{"rendered":"Pramipexol Normon 0,18 mg Tablets"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/?post_type=product&amp;p=63273&amp;preview=true\">Pramipexol Normon 0,18 mg Tablets<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Laboratorios Normon, T\u00e2y Ban Nha, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-22815-21<\/b><span style=\"font-weight: 400\">.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Pramipexol Normon 0,18 mg Tablets l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Pramipexol Normon 0,18 mg Tablets c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pramipexol (d\u01b0\u1edbi d\u1ea1ng dihydrochloride monohydrate)&#8230;&#8230;&#8230; 0,18mg.<\/span><\/p>\n<p><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/span><\/p>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VN-22815-21<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: T\u00e2y Ban Nha<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Pramipexol Normon 0,18 mg Tablets<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Pramipexole l\u00e0 ch\u1ea5t ch\u1ee7 v\u1eadn dopamine kh\u00f4ng ph\u1ea3i ergot. C\u00e1c nghi\u00ean c\u1ee9u in vitro \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng pramipexole c\u00f3 \u0111\u1ed9 \u0111\u1eb7c hi\u1ec7u cao \u0111\u1ed1i v\u1edbi th\u1ee5 th\u1ec3 D2 v\u00e0 c\u00f3 ho\u1ea1t t\u00ednh n\u1ed9i t\u1ea1i thu\u1ea7n t\u00fay, \u0111\u1ed3ng th\u1eddi \u00e1i l\u1ef1c c\u1ee7a n\u00f3 \u0111\u1ed1i v\u1edbi th\u1ee5 th\u1ec3 D3 cao h\u01a1n so v\u1edbi th\u1ee5 th\u1ec3 D2 v\u00e0 D4. S\u1ef1 li\u00ean quan c\u1ee7a s\u1ef1 k\u1ebft h\u1ee3p gi\u1eefa pramipexole v\u00e0 th\u1ee5 th\u1ec3 D3 v\u1edbi b\u1ec7nh Parkinson l\u00e0 kh\u00f4ng r\u00f5 r\u00e0ng. C\u01a1 ch\u1ebf ch\u00ednh x\u00e1c m\u00e0 pramipexole \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Parkinson v\u1eabn ch\u01b0a r\u00f5 r\u00e0ng, nh\u01b0ng hi\u1ec7n t\u1ea1i n\u00f3 \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c thu nh\u1eadn c\u00e1c th\u1ee5 th\u1ec3 dopamine \u1edf th\u1ec3 v\u00e2n. C\u00e1c th\u1eed nghi\u1ec7m \u0111i\u1ec7n sinh l\u00fd \u1edf \u0111\u1ed9ng v\u1eadt cho th\u1ea5y pramipexole c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u1ea7n s\u1ed1 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh giai \u0111o\u1ea1n \u0111\u1ea7u b\u1eb1ng c\u00e1ch thu gi\u1eef c\u00e1c th\u1ee5 th\u1ec3 dopamine \u1edf th\u1ec3 v\u00e2n v\u00e0 ch\u1ea5t \u0111en.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u1ea3n ph\u1ea9m n\u00e0y \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh ch\u00f3ng v\u00e0 ho\u00e0n to\u00e0n sau khi u\u1ed1ng. Sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i cao h\u01a1n 90% v\u00e0 n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c t\u1eeb 1 \u0111\u1ebfn 3 gi\u1edd sau khi d\u00f9ng thu\u1ed1c. D\u00f9ng thu\u1ed1c c\u00f9ng v\u1edbi th\u1ee9c \u0103n kh\u00f4ng l\u00e0m gi\u1ea3m m\u1ee9c \u0111\u1ed9 nh\u01b0ng l\u00e0m gi\u1ea3m t\u1ed1c \u0111\u1ed9 h\u1ea5p thu c\u1ee7a s\u1ea3n ph\u1ea9m n\u00e0y.S\u1ea3n ph\u1ea9m n\u00e0y c\u00f3 \u0111\u1ed9ng h\u1ecdc tuy\u1ebfn t\u00ednh v\u1edbi n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng \u00edt thay \u0111\u1ed5i gi\u1eefa c\u00e1c b\u1ec7nh nh\u00e2n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Trong c\u01a1 th\u1ec3 ng\u01b0\u1eddi, s\u1ea3n ph\u1ea9m n\u00e0y c\u00f3 t\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng r\u1ea5t th\u1ea5p (d\u01b0\u1edbi 20%) v\u00e0 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 l\u1edbn (400L). C\u00f3 th\u1ec3 quan s\u00e1t th\u1ea5y n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00f4 n\u00e3o chu\u1ed9t r\u1ea5t cao (g\u1ea5p kho\u1ea3ng 8 l\u1ea7n n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng), s\u1ef1 chuy\u1ec3n h\u00f3a c\u1ee7a s\u1ea3n ph\u1ea9m n\u00e0y trong c\u01a1 th\u1ec3 chu\u1ed9t \u0111\u1ef1c r\u1ea5t th\u1ea5p.<\/span><\/p>\n<p><span style=\"font-weight: 400\">S\u1ea3n ph\u1ea9m n\u00e0y ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i qua th\u1eadn, chi\u1ebfm kho\u1ea3ng 80% li\u1ec1u d\u00f9ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Kho\u1ea3ng 90% thu\u1ed1c g\u1eafn nh\u00e3n 14c \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua th\u1eadn, d\u01b0\u1edbi 2% qua ph\u00e2n . \u0110\u1ed9 thanh th\u1ea3i to\u00e0n ph\u1ea7n c\u1ee7a s\u1ea3n ph\u1ea9m n\u00e0y l\u00e0 kho\u1ea3ng 500 ml\/ph\u00fat v\u00e0 \u0111\u1ed9 thanh th\u1ea3i \u1edf th\u1eadn l\u00e0 kho\u1ea3ng 400 ml\/ph\u00fat. Th\u1eddi gian b\u00e1n h\u1ee7y th\u1ea3i tr\u1eeb (t 1\/2 ) dao \u0111\u1ed9ng t\u1eeb 8-12 gi\u1edd \u1edf ng\u01b0\u1eddi tr\u1ebb v\u00e0 ng\u01b0\u1eddi gi\u00e0.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Pramipexol Normon 0,18 mg Tablets \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Pramipexol Normon 0,18 mg Tablets \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh Parkinson (c\u1ee9ng kh\u1edbp, run, co th\u1eaft c\u01a1 v\u00e0 ki\u1ec3m so\u00e1t c\u01a1 k\u00e9m). Pramipexole c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng ch\u00e2n kh\u00f4ng y\u00ean (RLS).<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Pramipexol Normon 0,18 mg Tablets<\/span><\/h2>\n<p>&nbsp;<\/p>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400\">\u0110\u1ed1i t\u01b0\u1ee3ng<\/span><\/td>\n<td><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Li\u1ec1u kh\u1edfi \u0111\u1ea7u<\/span><\/td>\n<td><span style=\"font-weight: 400\">Li\u1ec1u kh\u1edfi \u0111\u1ea7u l\u00e0 0,375 mg m\u1ed7i ng\u00e0y, sau \u0111\u00f3 t\u0103ng d\u1ea7n li\u1ec1u sau m\u1ed7i 5 \u0111\u1ebfn 7 ng\u00e0y. N\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng g\u1eb7p ph\u1ea3i c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i kh\u00f4ng th\u1ec3 dung n\u1ea1p \u0111\u01b0\u1ee3c th\u00ec n\u00ean t\u0103ng li\u1ec1u \u0111\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c hi\u1ec7u qu\u1ea3 t\u1ed1i \u0111a.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Li\u1ec1u duy tr\u00ec<\/span><\/td>\n<td><span style=\"font-weight: 400\">0.264 mg \u0111\u1ebfn t\u1ed1i \u0111a 3.3 mg\/ng\u00e0y, li\u1ec1u c\u1ee5 th\u1ec3 ph\u1ee5 thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 \u0111\u00e1p \u1ee9ng v\u00e0 th\u1ec3 tr\u1ea1ng c\u1ee7a b\u1ec7nh nh\u00e2n.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Ng\u1eebng \u0111i\u1ec1u tr\u1ecb<\/span><\/td>\n<td><span style=\"font-weight: 400\">Vi\u1ec7c ng\u1eebng \u0111\u1ed9t ng\u1ed9t \u0111i\u1ec1u tr\u1ecb b\u1eb1ng dopaminergic c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a h\u1ed9i ch\u1ee9ng \u00e1c t\u00ednh th\u1ea7n kinh. Do \u0111\u00f3, n\u00ean ng\u1eebng thu\u1ed1c d\u1ea7n d\u1ea7n v\u1edbi t\u1ed1c \u0111\u1ed9 0,75 mg m\u1ed7i ng\u00e0y cho \u0111\u1ebfn khi gi\u1ea3m li\u1ec1u h\u00e0ng ng\u00e0y xu\u1ed1ng 0,75 mg. Sau \u0111\u00f3 n\u00ean gi\u1ea3m li\u1ec1u 0,375 mg m\u1ed7i ng\u00e0y.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Pramipexol Normon 0,18 mg Tablets trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Kh\u00f4ng d\u00f9ng trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Pramipexol Normon 0,18 mg Tablets<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Khi b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh Parkinson b\u1ecb suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn d\u00f9ng s\u1ea3n ph\u1ea9m n\u00e0y, n\u00ean gi\u1ea3m li\u1ec1u.<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u1ea2o gi\u00e1c l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c ch\u1ee7 v\u1eadn dopamine v\u00e0 levodopa. B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c th\u00f4ng b\u00e1o r\u1eb1ng \u1ea3o gi\u00e1c (ch\u1ee7 y\u1ebfu l\u00e0 \u1ea3o gi\u00e1c) c\u00f3 th\u1ec3 x\u1ea3y ra. Trong b\u1ec7nh Parkinson ti\u1ebfn tri\u1ec3n, vi\u1ec7c s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p levodopa c\u00f3 th\u1ec3 g\u00e2y r\u1ed1i lo\u1ea1n v\u1eadn \u0111\u1ed9ng khi t\u0103ng li\u1ec1u ban \u0111\u1ea7u c\u1ee7a s\u1ea3n ph\u1ea9m n\u00e0y. N\u1ebfu x\u1ea3y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 n\u00eau tr\u00ean, n\u00ean gi\u1ea3m li\u1ec1u levodopa.<\/span><\/p>\n<p><span style=\"font-weight: 400\">S\u1ea3n ph\u1ea9m n\u00e0y c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7 v\u00e0 l\u00ean c\u01a1n bu\u1ed3n ng\u1ee7 \u0111\u1ed9t ng\u1ed9t, \u0111\u1eb7c bi\u1ec7t \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh Parkinson. B\u1ec7nh nh\u00e2n ph\u1ea3i \u0111\u01b0\u1ee3c th\u00f4ng b\u00e1o v\u1ec1 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0y v\u00e0 n\u00ean th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng s\u1ea3n ph\u1ea9m n\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e3 t\u1eebng g\u1eb7p t\u00e1c d\u1ee5ng ph\u1ee5 bu\u1ed3n ng\u1ee7 v\u00e0\/ho\u1eb7c c\u00e1c c\u01a1n bu\u1ed3n ng\u1ee7 \u0111\u1ed9t ng\u1ed9t ph\u1ea3i tr\u00e1nh l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, \u0111\u1ed3ng th\u1eddi n\u00ean c\u00e2n nh\u1eafc vi\u1ec7c gi\u1ea3m li\u1ec1u ho\u1eb7c ng\u1eebng \u0111i\u1ec1u tr\u1ecb.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Do c\u00f3 th\u1ec3 c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5, b\u1ec7nh nh\u00e2n n\u00ean th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c an th\u1ea7n ho\u1eb7c r\u01b0\u1ee3u kh\u00e1c trong khi d\u00f9ng pramipexole.<\/span><\/p>\n<p><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n b\u1ecb r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c ch\u1ee7 v\u1eadn dopamine n\u1ebfu l\u1ee3i \u00edch ti\u1ec1m n\u0103ng v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi r\u1ee7i ro. N\u00ean tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi pramipexole v\u1edbi thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">N\u00ean kh\u00e1m m\u1eaft th\u01b0\u1eddng xuy\u00ean ho\u1eb7c khi c\u00f3 b\u1ea5t th\u01b0\u1eddng v\u1ec1 th\u1ecb gi\u00e1c.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u1ea7n ch\u00fa \u00fd \u0111\u1ebfn nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh tim m\u1ea1ch n\u1eb7ng. V\u00ec li\u1ec7u ph\u00e1p dopaminergic c\u00f3 li\u00ean quan \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a h\u1ea1 huy\u1ebft \u00e1p th\u1ebf \u0111\u1ee9ng n\u00ean c\u1ea7n theo d\u00f5i huy\u1ebft \u00e1p, \u0111\u1eb7c bi\u1ec7t l\u00e0 trong giai \u0111o\u1ea1n \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ed9i ch\u1ee9ng \u00e1c t\u00ednh th\u1ea7n kinh \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi ng\u1eebng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng dopaminergic \u0111\u1ed9t ng\u1ed9t\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Pramipexole c\u00f3 th\u1ec3 g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng. Trong \u0111\u00f3 c\u00f3:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea3m gi\u00e1c cho\u00e1ng v\u00e1ng, nh\u01b0 th\u1ec3 b\u1ea1n s\u1eafp ng\u1ea5t \u0111i;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u1ea2o gi\u00e1c (nh\u00ecn ho\u1eb7c nghe th\u1ea5y nh\u1eefng \u0111i\u1ec1u kh\u00f4ng c\u00f3 th\u1eadt);<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Bu\u1ed3n ng\u1ee7 c\u1ef1c \u0111\u1ed9, ng\u1ee7 thi\u1ebfp \u0111i \u0111\u1ed9t ng\u1ed9t, ngay c\u1ea3 khi \u0111\u00e3 c\u1ea3m th\u1ea5y t\u1ec9nh t\u00e1o ;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Run, co gi\u1eadt ho\u1eb7c c\u1eed \u0111\u1ed9ng c\u01a1 kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110au c\u01a1 kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n , \u0111au ho\u1eb7c y\u1ebfu;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">V\u1ea5n \u0111\u1ec1 v\u1ec1 th\u1ecb l\u1ef1c; ho\u1eb7c<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nh\u1eefng thay \u0111\u1ed5i v\u1ec1 t\u01b0 th\u1ebf kh\u00f4ng th\u1ec3 ki\u1ec3m so\u00e1t, ch\u1eb3ng h\u1ea1n nh\u01b0 v\u00f4 t\u00ecnh c\u00fai c\u1ed5 v\u1ec1 ph\u00eda tr\u01b0\u1edbc, c\u00fai v\u1ec1 ph\u00eda tr\u01b0\u1edbc \u1edf th\u1eaft l\u01b0ng ho\u1eb7c nghi\u00eang sang m\u1ed9t b\u00ean khi b\u1ea1n ng\u1ed3i, \u0111\u1ee9ng ho\u1eb7c \u0111i.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 nh\u1ea7m l\u1eabn ho\u1eb7c \u1ea3o gi\u00e1c c\u00f3 th\u1ec3 x\u1ea3y ra nhi\u1ec1u h\u01a1n \u1edf ng\u01b0\u1eddi l\u1edbn tu\u1ed5i.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u00f3 th\u1ec3 t\u0103ng ham mu\u1ed1n t\u00ecnh d\u1ee5c, ham mu\u1ed1n \u0111\u00e1nh b\u1ea1c b\u1ea5t th\u01b0\u1eddng ho\u1eb7c c\u00e1c ham mu\u1ed1n m\u00e3nh li\u1ec7t kh\u00e1c khi d\u00f9ng pramipexole.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p c\u1ee7a pramipexole c\u00f3 th\u1ec3 bao g\u1ed3m:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Co th\u1eaft c\u01a1 ho\u1eb7c y\u1ebfu c\u01a1;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, suy nh\u01b0\u1ee3c;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nh\u1ea7m l\u1eabn, v\u1ea5n \u0111\u1ec1 v\u1ec1 tr\u00ed nh\u1edb;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4 mi\u1ec7ng ;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Bu\u1ed3n n\u00f4n , t\u00e1o b\u00f3n ;<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110i ti\u1ec3u nhi\u1ec1u; ho\u1eb7c<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">V\u1ea5n \u0111\u1ec1 v\u1ec1 gi\u1ea5c ng\u1ee7 (m\u1ea5t ng\u1ee7), gi\u1ea5c m\u01a1 b\u1ea5t th\u01b0\u1eddng.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Pramipexole c\u00f3 m\u1ee9c \u0111\u1ed9 g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng r\u1ea5t th\u1ea5p (d\u01b0\u1edbi 20%), h\u1ea7u nh\u01b0 kh\u00f4ng x\u1ea3y ra chuy\u1ec3n h\u00f3a sinh h\u1ecdc trong c\u01a1 th\u1ec3 nam gi\u1edbi, do \u0111\u00f3 pramipexole kh\u00f4ng th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 g\u1eafn k\u1ebft ho\u1eb7c g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn protein huy\u1ebft t\u01b0\u01a1ng. \u0110\u01b0\u1ee3c l\u00e0m s\u1ea1ch b\u1eb1ng chuy\u1ec3n h\u00f3a sinh h\u1ecdc. V\u00ec c\u00e1c thu\u1ed1c kh\u00e1ng cholinergic ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb th\u00f4ng qua chuy\u1ec3n h\u00f3a sinh h\u1ecdc, m\u1eb7c d\u00f9 s\u1ef1 t\u01b0\u01a1ng t\u00e1c c\u1ee7a pramipexole v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng cholinergic ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u n\u00ean ng\u01b0\u1eddi ta cho r\u1eb1ng kh\u1ea3 n\u0103ng x\u1ea3y ra t\u01b0\u01a1ng t\u00e1c nh\u01b0 v\u1eady l\u00e0 r\u1ea5t h\u1ea1n ch\u1ebf. Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc gi\u1eefa prixol v\u00e0 selegiline ho\u1eb7c levodopa.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Cimetidine c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u1ed1c \u0111\u1ed9 thanh th\u1ea3i pramipexole \u1edf th\u1eadn kho\u1ea3ng 34%, c\u00f3 th\u1ec3 do \u1ee9c ch\u1ebf h\u1ec7 th\u1ed1ng v\u1eadn chuy\u1ec3n b\u00e0i ti\u1ebft cation \u1edf \u1ed1ng th\u1eadn. Do \u0111\u00f3, c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf ho\u1eb7c th\u1ea3i tr\u1eeb qua con \u0111\u01b0\u1eddng thanh th\u1ea3i t\u00edch c\u1ef1c qua th\u1eadn nh\u01b0 cimetidine v\u00e0 amantadine, c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi pramipexole v\u00e0 l\u00e0m gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a m\u1ed9t ho\u1eb7c c\u1ea3 hai lo\u1ea1i thu\u1ed1c. Khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi c\u00e1c thu\u1ed1c n\u00e0y v\u1edbi pramipexole, n\u00ean c\u00e2n nh\u1eafc vi\u1ec7c gi\u1ea3m li\u1ec1u pramipexole. Khi s\u1ea3n ph\u1ea9m n\u00e0y \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi levodopa, n\u00ean gi\u1ea3m li\u1ec1u levodopa khi t\u0103ng li\u1ec1u c\u1ee7a s\u1ea3n ph\u1ea9m n\u00e0y, trong khi li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ch\u1ed1ng Parkinson kh\u00e1c v\u1eabn kh\u00f4ng thay \u0111\u1ed5i.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Do c\u00f3 th\u1ec3 c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5, b\u1ec7nh nh\u00e2n n\u00ean c\u1ea9n th\u1eadn khi s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c an th\u1ea7n ho\u1eb7c r\u01b0\u1ee3u kh\u00e1c trong khi d\u00f9ng pramipexole.<\/span><\/p>\n<p><span style=\"font-weight: 400\">N\u00ean tr\u00e1nh s\u1eed d\u1ee5ng pramipexole \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng khi mang thai v\u00e0 cho con b\u00fa. Do t\u00e1c d\u1ee5ng c\u1ee7a pramipexole trong th\u1eddi k\u1ef3 mang thai v\u00e0 cho con b\u00fa ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u. N\u00f3 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng g\u00e2y qu\u00e1i thai tr\u00ean chu\u1ed9t v\u00e0 th\u1ecf; tuy nhi\u00ean, n\u00f3 g\u00e2y \u0111\u1ed9c cho ph\u00f4i chu\u1ed9t \u1edf li\u1ec1u g\u00e2y \u0111\u1ed9c cho chu\u1ed9t m\u1eb9. V\u1eady n\u00ean ch\u1ec9 s\u1eed d\u1ee5ng khi th\u1ef1c s\u1ef1 c\u1ea7n thi\u1ebft.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Hi\u1ec7n nay ch\u01b0a c\u00f3 qu\u00e1 nhi\u1ec1u c\u00e1c kinh nghi\u1ec7m l\u00e2m s\u00e0ng tr\u00ean \u0111i\u1ec1u tr\u1ecb c\u00e1c t\u00ecnh tr\u1ea1ng qu\u00e1 li\u1ec1u thu\u1ed1c. M\u1ed9t s\u1ed1 bi\u1ec3u hi\u1ec7n c\u00f3 th\u1ec3 x\u1ea3y ra nh\u01b0 bu\u1ed3n n\u00f4n, n\u00f4n, k\u00edch th\u00edch, \u1ea3o gi\u00e1c, h\u1ea1 huy\u1ebft \u00e1p.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Pramipexol Normon 0,18 mg Tablets gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Pramipexol Normon 0,18 mg Tablets hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:\u00a0\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/stalevo-200-50-200mg\/\"><span style=\"font-weight: 400\">Vi\u00ean n\u00e9n Stalevo 200\/50\/200mg<\/span><\/a><span style=\"font-weight: 400\"> c\u00f3 ch\u1ee9a 200mg Levodopa, 50mg Carbidopa v\u00e0 200mg Entacapone, \u0111\u01b0\u1ee3c d\u00f9ng cho b\u1ec7nh nh\u00e2n Parkinson c\u00f3 nh\u1eefng r\u1ed1i lo\u1ea1n v\u1eadn \u0111\u1ed9ng, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Orion Corporation-Novartis. Hi\u1ec7n thu\u1ed1c \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 2.750.000 \u0111\u1ed3ng\/ h\u1ed9p 1 l\u1ecd 100 vi\u00ean.<\/span><\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/masopen-250-25\/#:~:text=Thu%E1%BB%91c%20Masopen%20250%2F25%20%C4%91%C6%B0%E1%BB%A3c,h%E1%BB%99i%20ch%E1%BB%A9ng%20b%E1%BB%87nh%20v%E1%BB%81%20n%C3%A3o.&amp;text=L%C3%A0%20ti%E1%BB%81n%20th%C3%A2n%20c%E1%BB%A7a%20dopamin.\"><span style=\"font-weight: 400\">Thu\u1ed1c Masopen 250\/25<\/span><\/a><span style=\"font-weight: 400\"> \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn l\u00e0 thu\u1ed1c c\u00f3 ch\u1ee9a c\u00e1c th\u00e0nh ph\u1ea7n g\u1ed3m Levodopa, carbidopa, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00e1c ch\u1ee9ng b\u1ec7nh parkinson hay m\u1ed9t s\u1ed1 h\u1ed9i ch\u1ee9ng b\u1ec7nh v\u1ec1 n\u00e3o, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Hasan \u2013 Dermapharm. Hi\u1ec7n thu\u1ed1c \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 160.000 \u0111\u1ed3ng\/ H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Pramipexol Normon 0,18 mg Tablets ?<\/span><\/h2>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Pramipexol Normon 0,18 mg Tablets c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Pramipexol d\u01b0\u1edbi d\u1ea1ng dihydrochloride monohydrate, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Parkinson hi\u1ec7u qu\u1ea3.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n d\u1ec5 d\u00e0ng s\u1eed d\u1ee5ng, b\u1ea3o qu\u1ea3n v\u00e0 mang \u0111i.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Laboratorios Normon, T\u00e2y Ban Nha v\u1edbi c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t hi\u1ec7n \u0111\u1ea1i, ti\u00ean ti\u1ebfn n\u00ean c\u00e1c s\u1ea3n ph\u1ea9m \u0111\u1ea1t ch\u1ea5t l\u01b0\u1ee3ng \u0111\u1ed3ng \u0111\u1ec1u v\u00e0 uy t\u00edn.<\/span><\/td>\n<td><span style=\"font-weight: 400\">Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ra nh\u1eefng t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 t\u01b0\u01a1ng t\u00e1c trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng c\u1ea7n th\u1eadn tr\u1ecdng.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ta\u0301c gia\u0309 Anna R. Van Meter v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 7 &#8211; 8 n\u0103m 2021). <\/span><i><span style=\"font-weight: 400\">Pramipexole to Improve Cognition in Bipolar Disorder<\/span><\/i><span style=\"font-weight: 400\">. Th\u1eddi gian truy c\u1eadp ng\u00e0y 30 th\u00e1ng 12 n\u0103m 2023, t\u1eeb <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8238822\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8238822\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110\u01b0\u1ee3c vi\u1ebft b\u1edfi chuy\u00ean gia c\u1ee7a Pubchem. <\/span><i><span style=\"font-weight: 400\">Pramipexole<\/span><\/i><span style=\"font-weight: 400\">. Th\u1eddi gian truy c\u1eadp ng\u00e0y 30 th\u00e1ng 12 n\u0103m 2023, t\u1eeb <\/span><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Pramipexole\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Pramipexole<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p><span style=\"font-weight: 400\">Pramipexol Normon 0,18 mg Tablets c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Pramipexol d\u01b0\u1edbi d\u1ea1ng dihydrochloride monohydrate, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Parkinson hi\u1ec7u qu\u1ea3.<\/span><\/p>\n","protected":false},"author":490,"featured_media":63274,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-63273","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/63273","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=63273"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/63274"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=63273"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=63273"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=63273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}