{"id":59766,"date":"2023-11-29T22:15:52","date_gmt":"2023-11-29T15:15:52","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=59766"},"modified":"2025-07-24T13:44:02","modified_gmt":"2025-07-24T06:44:02","slug":"thuoc-utralene-100","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-utralene-100\/","title":{"rendered":"Utralene-100"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m\u00a0<a href=\"https:\/\/vnras.com\/drug\/thuoc-utralene-100\/\">thu\u1ed1c Utralene-100<\/a> l\u00e0 1 s\u1ea3n ph\u1ea9m c\u1ee7a h\u00e3ng D\u01b0\u1ee3c ph\u1ea9m Umedica Laboratories &#8211; \u1ea4n \u0110\u1ed9 s\u1ea3n xu\u1ea5t, c\u00f4ng ty D\u01b0\u1ee3c ph\u1ea9m T\u00e2y Huy ch\u1ecbu tr\u00e1ch nhi\u1ec7m nh\u1eadp kh\u1ea9u v\u00e0 ph\u00e2n ph\u1ed1i t\u1ea1i Vi\u1ec7t Nam v\u1edbi s\u1ed1 \u0111\u0103ng k\u00fd l\u00e0 VN-17227-13. Utralene-100 l\u00e0 thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m theo c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf thu h\u1ed3i c\u00f3 ch\u1ecdn l\u1ecdc Serotonin.<\/b><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c <\/span><span style=\"font-weight: 400\">Utralene-100 l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p>Trong m\u1ed7i vi\u00ean <b>Utralene-100 <\/b>c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n<\/p>\n<ul>\n<li style=\"font-weight: 400\">Sertraline: 100mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VN-17227-13<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: Umedica Laboratories &#8211; \u1ea4n \u0110\u1ed9<\/span><\/p>\n<p>\u0110\u01a1n v\u1ecb \u0111\u0103ng k\u00fd: D\u01b0\u1ee3c ph\u1ea9m T\u00e2y Huy.<\/p>\n<h2><span style=\"font-weight: 400\">Utralene-100 thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/span><\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Sertralin l\u00e0 thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m, d\u1eabn ch\u1ea5t naphthylamin, ho\u1ea1t \u0111\u1ed9ng theo c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc qu\u00e1 tr\u00ecnh t\u00e1i thu h\u1ed3i serotonin, t\u0103ng n\u1ed3ng \u0111\u1ed9 serotonin \u1edf khe sinap, d\u1eabn \u0111\u1ebfn t\u0103ng \u0111\u00e1p \u1ee9ng c\u1ee7a serotonin.<\/p>\n<p>Thu\u1ed1c \u00edt t\u00e1c d\u1ee5ng l\u00ean qu\u00e1 tr\u00ecnh t\u00e1i thu h\u1ed3i norepinephrin ho\u1eb7c dopamin, \u00edt ho\u1eb7c kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng kh\u00e1ng cholinergic, kh\u00e1ng histamin, ch\u1eb9n alpha, alpha, ho\u1eb7c beta-adrenergic khi d\u00f9ng v\u1edbi li\u1ec1u \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Do \u0111\u00f3, Sertralin \u0111\u01b0\u1ee3c xem l\u00e0 li\u1ec7u ph\u00e1p \u00edt g\u00e2y ADR (nh\u01b0 kh\u00f4 mi\u1ec7ng, nh\u00ecn m\u1edd, b\u00ed ti\u1ec3u, t\u00e1o b\u00f3n, l\u00fa l\u1eabn, h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf v\u00e0 bu\u1ed3n ng\u1ee7) h\u01a1n so v\u1edbi thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m ba v\u00f2ng v\u00e0 m\u1ed9t s\u1ed1 thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m kh\u00e1c.<\/p>\n<h3>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Sertralin h\u1ea5p thu ch\u1eadm nh\u01b0ng t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng ch\u1ec9 \u0111\u1ea1t v\u00e0o kho\u1ea3ng 22 &#8211; 36% do thu\u1ed1c b\u1ecb chuy\u1ec3n h\u00f3a b\u01b0\u1edbc 1 \u1edf gan n\u00ean. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau u\u1ed1ng 4,5 &#8211; 8,4 gi\u1edd.<\/p>\n<p>Ph\u00e2n b\u1ed1: C\u00e1c ph\u00e2n t\u1eed Sertralin ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i v\u00e0o c\u00e1c m\u00f4 v\u00e0 d\u1ecbch trong c\u01a1 th\u1ec3, qua \u0111\u01b0\u1ee3c h\u00e0ng r\u00e0o m\u00e1u &#8211; n\u00e3o v\u00e0 s\u1eefa m\u1eb9; kh\u1ea3 n\u0103ng li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng l\u00e0 kho\u1ea3ng 98%, ch\u1ee7 y\u1ebfu l\u00e0 Albumin v\u00e0 acid alpha,-glycoprotein.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Thu\u1ed1c b\u1ecb chuy\u1ec3n h\u00f3a ph\u1ea7n l\u1edbn khi qua gan, t\u1ea1o th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh l\u00e0 N-desmethylsertralin c\u00f3 ho\u1ea1t t\u00ednh y\u1ebfu h\u01a1n ch\u1ea5t ban \u0111\u1ea7u.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Qu\u00e1 tr\u00ecnh th\u1ea3i tr\u1eeb c\u1ee7a Sertralin ch\u1ee7 y\u1ebfu d\u01b0\u1edbi d\u1ea1ng chuy\u1ec3n h\u00f3a qua ph\u00e2n v\u00e0 n\u01b0\u1edbc ti\u1ec3u. Ch\u1ec9 m\u1ed9t l\u01b0\u1ee3ng r\u1ea5t nh\u1ecf (d\u01b0\u1edbi 0,2%) li\u1ec1u n\u1ea1p \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng chuy\u1ec3n h\u00f3a. N\u1eeda \u0111\u1eddi th\u1ea3i tr\u1eeb c\u1ee7a thu\u1ed1c l\u00e0 kho\u1ea3ng 25 &#8211; 26 gi\u1edd v\u00e0 n\u1eeda \u0111\u1eddi th\u1ea3i tr\u1eeb c\u1ee7a ch\u1ea5t chuy\u1ec3n h\u00f3a N-desmethylsertralin l\u00e0 62 &#8211; 104 gi\u1edd.<\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Utralene-100 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p>Utralene \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau \u0111\u00e2y:<\/p>\n<p>R\u1ed1i lo\u1ea1n tr\u1ea7m c\u1ea3m c\u00f3\/ ho\u1eb7c kh\u00f4ng c\u00f3 k\u00e8m theo ch\u1ee9ng s\u1ee3 ch\u1ed7 \u0111\u00f4ng ng\u01b0\u1eddi \u0111\u1eb7c tr\u01b0ng b\u1edfi c\u00e1c c\u01a1n ho\u1ea3ng lo\u1ea1n b\u1ea5t th\u00ecnh l\u00ecnh v\u00e0 lo l\u1eafng v\u1ec1 s\u1ef1 gia t\u0103ng b\u1ec7nh, lo l\u1eafng v\u1ec1 c\u00e1c bi\u1ebfn ch\u1ee9ng v\u00e0 h\u1eadu qu\u1ea3 c\u1ee7a b\u1ec7nh ho\u1eb7c s\u1ef1 thay \u0111\u1ed5i th\u00e1i \u0111\u1ed9, h\u00e0nh vi li\u00ean quan \u0111\u1ebfn b\u1ec7nh n\u00e0y<\/p>\n<p>R\u1ed1i lo\u1ea1n ho\u1ea3ng s\u1ee3 k\u00e8m ho\u1eb7c kh\u00f4ng k\u00e8m theo \u00e1m \u1ea3nh s\u1ee3 kho\u1ea3ng tr\u1ed1ng.<\/p>\n<p>Ch\u1ee9ng r\u1ed1i lo\u1ea1n \u00e1m \u1ea3nh &#8211; c\u01b0\u1ee1ng b\u1ee9c \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 6 &#8211; 17 tu\u1ed5i.<\/p>\n<p>R\u1ed1i lo\u1ea1n lo \u00e2u x\u00e3 h\u1ed9i; stress sau sang ch\u1ea5n.<\/p>\n<p>R\u1ed1i lo\u1ea1n lo \u00e2u ti\u1ec1n kinh nguy\u1ec7t.<\/p>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng <\/span><span style=\"font-weight: 400\">thu\u1ed1c Utralene-100<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Utralene-100<\/span><\/h3>\n<h4>\u0110i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m \u1edf ng\u01b0\u1eddi l\u1edbn<\/h4>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u 0.5 vi\u00ean\/ng\u00e0y.<\/p>\n<p>\u0110\u00e1nh gi\u00e1 c\u1ea3i thi\u1ec7n sau \u00edt nh\u1ea5t 1 tu\u1ea7n; n\u1ebfu kh\u00f4ng c\u00f3 ti\u1ebfn tri\u1ec3n th\u00ec t\u0103ng th\u00eam m\u1ed7i ng\u00e0y 0.5 vi\u00ean cho \u0111\u1ebfn li\u1ec1u t\u1ed1i \u0111a 2 vi\u00ean m\u1ed7i ng\u00e0y.<\/p>\n<p>T\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb th\u01b0\u1eddng b\u1eaft \u0111\u1ea7u trong v\u00f2ng 7 ng\u00e0y \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Ch\u01b0a r\u00f5 hi\u1ec7u qu\u1ea3 c\u1ee7a sertralin trong \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m \u1edf tr\u1ebb em.<\/p>\n<h4>R\u1ed1i lo\u1ea1n \u00e1m \u1ea3nh c\u01b0\u1ee1ng b\u1ee9c<\/h4>\n<p>Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 13 tu\u1ed5i tr\u1edf l\u00ean: Li\u1ec1u kh\u1edfi \u0111\u1ea7u 0.5 vi\u00ean\/l\u1ea7n\/ ng\u00e0y.<\/p>\n<p>Tr\u1ebb em t\u1eeb 6 &#8211; 12 tu\u1ed5i: Li\u1ec1u kh\u1edfi \u0111\u1ea7u 0.25 vi\u00ean d\u00f9ng ng\u00e0y 1 l\u1ea7n.<\/p>\n<p>T\u0103ng li\u1ec1u th\u00eam m\u1ed7i 0.5 vi\u00ean\/ ng\u00e0y (tr\u1ebb em 6 &#8211; 12 tu\u1ed5i l\u00e0 0.25 vi\u00ean); t\u1ed1i \u0111a 2 vi\u00ean\/ng\u00e0y n\u1ebfu c\u1ea7n thi\u1ebft.<\/p>\n<p>Kho\u1ea3ng c\u00e1ch t\u0103ng li\u1ec1u t\u1ed1i thi\u1ec3u l\u00e0 1 tu\u1ea7n.<\/p>\n<p>\u0110a s\u1ed1 ng\u01b0\u1eddi b\u1ec7nh \u0111\u00e1p \u1ee9ng v\u1edbi li\u1ec1u 0.5 vi\u00ean -1 vi\u00ean m\u1ed7i ng\u00e0y (tr\u1ebb em 6 &#8211; 12 tu\u1ed5i l\u00e0 0.25 -0.5 vi\u00ean).<\/p>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u v\u1ec1 vi\u1ec7c \u0111i\u1ec1u tri sertralin cho tr\u1ebb em d\u01b0\u1edbi 6 tu\u1ed5i.<\/p>\n<h4>R\u1ed1i lo\u1ea1n ho\u1ea3ng s\u1ee3, n\u1ed5i loan stress sau sang ch\u1ea5n, r\u1ed1i lo\u1ea1n lo \u00e2u x\u00e3 h\u1ed9i<\/h4>\n<p>Ng\u01b0\u1eddi l\u1edbn li\u1ec1u kh\u1edfi \u0111\u1ea7u 0.25 vi\u00ean\/ng\u00e0y.<\/p>\n<p>Sau m\u1ed9t tu\u1ea7n, t\u00f9y v\u00e0o \u0111\u00e1p \u1ee9ng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n<p>C\u00f3 th\u1ec3 t\u0103ng li\u1ec1u l\u00ean m\u1ed7i 0.5 vi\u00ean\/ 1 l\u1ea7n trong ng\u00e0y cho \u0111\u1ebfn khi c\u00f3 hi\u1ec7u qu\u1ea3 ho\u1eb7c \u0111\u1ebfn t\u1ed1i \u0111a 2 vi\u00ean\/ ng\u00e0y<\/p>\n<h4>\u0110\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t<\/h4>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i: C\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u do nguy c\u01a1 h\u1ea1 natri huy\u1ebft.<\/p>\n<p>Ng\u01b0\u1eddi suy th\u1eadn: Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/p>\n<p>B\u00eanh nh\u00e2n suy gan: D\u00f9ng th\u1eadn tr\u1ecdng, gi\u1ea3m li\u1ec1u ho\u1eb7c gi\u1ea3m s\u1ed1 l\u1ea7n d\u00f9ng thu\u1ed1c do thu\u1ed1c chuy\u1ec3n h\u00f3a nhi\u1ec1u \u1edf gan.<\/p>\n<h3>Utralene-100 c\u00e1ch d\u00f9ng nh\u01b0 th\u1ebf n\u00e0o?<\/h3>\n<p>Vi\u00ean n\u00e9n bao phim Utralene \u0111\u01b0\u1ee3c d\u00f9ng theo \u0111\u01b0\u1eddng u\u1ed1ng c\u00f9ng v\u1edbi n\u01b0\u1edbc l\u1ecdc.<\/p>\n<p>U\u1ed1ng thu\u1ed1c trong ho\u1eb7c sau b\u1eefa \u0103n h\u00e0ng ng\u00e0y v\u00ed th\u1ee9c \u0103n kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c.<\/p>\n<p>Kh\u00f4ng t\u1ef1 \u00fd thay \u0111\u1ed5i c\u00e1ch s\u1eed d\u1ee5ng thu\u1ed1c theo \u00fd ki\u1ebfn c\u00e1 nh\u00e2n.<\/p>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng Utralene-100 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p>Ng\u01b0\u1eddi qu\u00e1 m\u1eabn c\u1ea3m v\u1edbi sertraline ho\u1eb7c b\u1ea5t c\u1ee9 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Sertraline kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf monoamino oxidase (MAX) bao g\u1ed3m selegiline, moclobemide v\u00e0 linezolide-m\u1ed9t ch\u1ea5t kh\u00e1ng khu\u1ea9n c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf thu\u1eadn ngh\u1ecbch monoamino oxidase (MAO).<\/p>\n<p>Setraline kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi pimozide.<\/p>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng Utralene-100 <\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<p>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Setraline tr\u00ean c\u00e1c b\u1ec7nh nh\u00e2n c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 g\u00e2y k\u00e9o d\u00e0i kho\u1ea3ng QT\/xo\u1eafn \u0111\u1ec9nh do thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 xo\u1eafn \u0111\u1ec9nh.<\/p>\n<p>S\u1eed d\u1ee5ng sertralin cho c\u00e1c b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed h\u01b0ng c\u1ea3m, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t do thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m l\u00e0m n\u1eb7ng th\u00eam c\u00e1c tri\u1ec7u ch\u1ee9ng tr\u00ean t\u00e2m th\u1ea7n, do \u0111\u00f3 c\u1ea7n theo d\u00f5i h\u00e0nh vi c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh khi \u0111i\u1ec1u tri.<\/p>\n<p>Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb cho c\u00e1c b\u1ec7nh nh\u00e2n \u0111\u1ed9ng kinh ho\u1eb7c ti\u1ec1n s\u1eed \u0111\u1ed9ng kinh, Setraline c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 co gi\u1eadt. Ng\u1eebng d\u00f9ng thu\u1ed1c \u0111\u1ed1i v\u1edbi t\u1ea5t c\u1ea3 c\u00e1c b\u1ec7nh nh\u00e2n c\u00f3 d\u1ea5u hi\u1ec7u co gi\u1eadt.<\/p>\n<p>B\u1ec7nh nh\u00e2n tr\u1ea7m c\u1ea3m, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng sertralin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u00fd ngh\u0129 t\u1ef1 s\u00e1t. C\u1ea7n ki\u1ec3m so\u00e1t ch\u1eb7t ch\u1ebd b\u1ec7nh nh\u00e2n trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb ngay c\u1ea3 khi tri\u1ec7u ch\u1ee9ng b\u1ec7nh \u0111\u00e3 thuy\u00ean gi\u1ea3m.<\/p>\n<p>H\u00e0nh vi li\u00ean quan \u0111\u1ebfn t\u1ef1 s\u00e1t (\u00fd t\u01b0\u1edfng ho\u1eb7c h\u00e0nh vi t\u1ef1 s\u00e1t) v\u00e0 tr\u1ea1ng th\u00e1i k\u00edch th\u00edch, c\u00e1u g\u1eaft, gi\u1eadn d\u1eef, h\u00e0nh vi g\u00e2y h\u1ea5n th\u01b0\u1eddng \u0111\u01b0\u1ee3c ghi nh\u1eadn tr\u00ean c\u00e1c tr\u1ebb \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m.<\/p>\n<p>Do v\u1eady, kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng sertralin cho tr\u1ebb em v\u00e0 thanh thi\u1ebfu ni\u00ean d\u01b0\u1edbi 18 tu\u1ed5i, tr\u1eeb khi b\u1ecb ch\u1ee9ng r\u1ed1i lo\u1ea1n \u00e1m \u1ea3nh &#8211; c\u01b0\u1ee1ng b\u1ee9c.<\/p>\n<p>S\u1eed d\u1ee5ng thu\u1ed1c tr\u00ean b\u1ec7nh nh\u00e2n cao tu\u1ed5i, ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c l\u1ee3i ti\u1ec3u ho\u1eb7c gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n do thu\u1ed1c c\u00f3 nguy c\u01a1 g\u00e2y gi\u1ea3m natri huy\u1ebft.<\/p>\n<p>Gi\u1ea3m li\u1ec1u t\u1eeb t\u1eeb tr\u01b0\u1edbc khi ng\u1eebng thu\u1ed1c \u0111\u1ec3 tr\u00e1nh hi\u1ec7n t\u01b0\u1ee3ng cai thu\u1ed1c. Nguy c\u01a1 xu\u1ea5t hi\u1ec7n tri\u1ec7u ch\u1ee9ng cai thu\u1ed1c ph\u1ee5 thu\u1ed9c v\u00e0o th\u1eddi gian \u0111i\u1ec1u tr\u1ecb, li\u1ec1u l\u01b0\u1ee3ng c\u0169ng nh\u01b0 t\u1ef7 l\u1ec7 gi\u1ea3m li\u1ec1u.<\/p>\n<p>V\u1edbi b\u1ec7nh nh\u00e2n suy gan, c\u1ea7n gi\u1ea3m li\u1ec1u ho\u1eb7c gi\u1ea3m s\u1ed1 l\u1ea7n d\u00f9ng \u1edf c\u00e1c thu\u1ed1c c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n sertralin.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng do thu\u1ed1c l\u00e0m thay \u0111\u1ed5i n\u1ed3ng \u0111\u1ed9 Glucose huy\u1ebft.<\/p>\n<p>B\u1ec7nh nh\u00e2n m\u1eafc ch\u1ee9ng gl\u00f4c\u00f4m g\u00f3c \u0111\u00f3ng ho\u1eb7c ti\u1ec1n s\u1eed gl\u00f4c\u00f4m c\u1ea7n \u0111\u01b0\u1ee3c c\u1ea3nh b\u00e1o tr\u01b0\u1edbc v\u1ec1 nguy c\u01a1 g\u00e2y gi\u00e3n \u0111\u1ed3ng t\u1eed, g\u00e2y h\u1eb9p g\u00f3c \u0111\u00f3ng v\u00e0 t\u0103ng \u00e1p l\u1ef1c nh\u00e3n c\u1ea7u, t\u0103ng nh\u00e3n \u00e1p g\u00f3c \u0111\u00f3ng c\u1ee7a thu\u1ed1c.<\/p>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/h3>\n<h4>C\u00e1c tri\u1ec7u ch\u1ee9ng b\u1ea5t l\u1ee3i c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i trong qu\u00e1 tr\u00ecnh d\u00f9ng thu\u1ed1c<\/h4>\n<table style=\"border-collapse: collapse;width: 100%;height: 229px\">\n<tbody>\n<tr style=\"height: 21px\">\n<td style=\"width: 33.3333%;height: 21px\">R\u1ea5t th\u01b0\u1eddng g\u1eb7p<\/td>\n<td style=\"width: 33.3333%;height: 21px\">TKTW: m\u1ea5t ng\u1ee7 (19%), ch\u00f3ng m\u1eb7t (11%), bu\u1ed3n ng\u1ee7 (13%), \u0111au \u0111\u1ea7u (21%).<\/p>\n<p>Ti\u00eau h\u00f3a: ti\u00eau ch\u1ea3y (18%), bu\u1ed3n n\u00f4n (24%), kh\u00f4 mi\u1ec7ng (14%). H\u1ec7 sinh s\u1ea3n: r\u1ed1i lo\u1ea1n xu\u1ea5t tinh (14%).<\/p>\n<p>To\u00e0n th\u00e2n: m\u1ec7t m\u1ecfi (10%).<\/td>\n<\/tr>\n<tr style=\"height: 208px\">\n<td style=\"width: 33.3333%;height: 208px\">Th\u01b0\u1eddng g\u1eb7p<\/td>\n<td style=\"width: 33.3333%;height: 208px\">Nhi\u1ec5m tr\u00f9ng: vi\u00eam h\u1ecdng.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: t\u0103ng ho\u1eb7c gi\u1ea3m th\u00e8m \u0103n.<\/p>\n<p>TKTW: tr\u1ea7m c\u1ea3m, r\u1ed1i lo\u1ea1n nh\u00e2n c\u00e1ch, \u00e1c m\u1ed9ng, lo \u00e2u, k\u00edch \u0111\u1ed9ng, gi\u1ea3m ham mu\u1ed1n, nghi\u1ebfn r\u0103ng khi ng\u1ee7, d\u1ecb c\u1ea3m, run, t\u0103ng tr\u01b0\u01a1ng l\u1ef1c c\u01a1, lo\u1ea1n v\u1ecb gi\u00e1c, gi\u1ea3m t\u1eadp trung.<\/p>\n<p>M\u1eaft: r\u1ed1i lo\u1ea1n t\u1ea7m nh\u00ecn.<\/p>\n<p>T\u1ea1i: \u00f9 tai.<\/p>\n<p>Tim m\u1ea1ch: tim \u0111\u1eadp nhanh.<\/p>\n<p>M\u1ea1ch: n\u00f3ng b\u1eebng m\u1eb7t.<\/p>\n<p>H\u00f4 h\u1ea5p: ng\u00e1p.<\/p>\n<p>Ti\u00eau h\u00f3a: \u0111au b\u1ee5ng, n\u00f4n, t\u00e1o b\u00f3n, kh\u00f3 ti\u00eau, tr\u01b0\u1edbng b\u1ee5ng.<\/p>\n<p>Da: ph\u00e1t ban, \u0111\u1ed5 m\u1ed3 h\u00f4i.<\/p>\n<p>C\u01a1 &#8211; x\u01b0\u01a1ng &#8211; kh\u1edbp: \u0111au kh\u1edbp, \u0111au c\u01a1.<\/p>\n<p>H\u1ec7 sinh s\u1ea3n: r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng.<\/p>\n<p>To\u00e0n th\u00e2n: \u0111au ng\u1ef1c, kh\u00f3 ch\u1ecbu.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%\">\u00cdt g\u1eb7p<\/td>\n<td style=\"width: 33.3333%\">Nhi\u1ec5m tr\u00f9ng: nhi\u1ec5m tr\u00f9ng h\u00f4 h\u1ea5p tr\u00ean, vi\u00eam m\u0169i.<\/p>\n<p>H\u1ec7 mi\u1ec5n d\u1ecbch: ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn.<\/p>\n<p>N\u1ed9i ti\u1ebft: suy gi\u00e1p.<\/p>\n<p>TKTW: hoang t\u01b0\u1edfng, hung h\u0103ng, s\u1ea3ng kho\u00e1i, l\u00e3nh \u0111\u1ea1m, \u00fd ngh\u0129 b\u1ea5t<\/p>\n<p>th\u01b0\u1eddng, co gi\u1eadt, co c\u01a1 t\u1ef1 ph\u00e1t, b\u1ea5t th\u01b0\u1eddng ph\u1ed1i h\u1ee3p c\u00e1c \u0111\u1ed9ng t\u00e1c,<\/p>\n<p>t\u0103ng \u0111\u1ed9ng, m\u1ea5t tr\u00ed nh\u1edb, gi\u1ea3m c\u1ea3m gi\u00e1c, r\u1ed1i lo\u1ea1n ng\u00f4n ng\u1eef, ch\u00f3ng m\u1eb7t, ng\u1ea5t, \u0111au n\u1eeda \u0111\u1ea7u.<\/p>\n<p>M\u1eaft: gi\u00e3n \u0111\u1ed3ng t\u1eed.<\/p>\n<p>T\u1ea1i: \u0111au tai.<\/p>\n<p>Tim: nh\u1ecbp tim nhanh.<\/p>\n<p>M\u1ea1ch: t\u0103ng huy\u1ebft \u00e1p, \u0111\u1ecf b\u1eebng m\u1eb7t.<\/p>\n<p>H\u00f4 h\u1ea5p: co th\u1eaft ph\u1ebf qu\u1ea3n, kh\u00f3 th\u1edf, ch\u1ea3y m\u00e1u cam.<\/p>\n<p>Ti\u00eau h\u00f3a: vi\u00eam th\u1ef1c qu\u1ea3n, kh\u00f3 nu\u1ed1t, tr\u0129, t\u0103ng ti\u1ebft n\u01b0\u1edbc b\u1ecdt, \u1ee3 h\u01a1i. Da: ph\u1ee7 quanh h\u1ed1c m\u1eaft, ph\u00f9 m\u1eb7t, ban xu\u1ea5t huy\u1ebft, r\u1ee5ng t\u00f3c, da kh\u00f4, m\u00e0y \u0111ay, m\u1ea9n ng\u1ee9a.<\/p>\n<p>C\u01a1 &#8211; x\u01b0\u01a1ng &#8211; kh\u1edbp: tho\u00e1i h\u00f3a kh\u1edbp, y\u1ebfu c\u01a1, \u0111au l\u01b0ng, co gi\u1eadt c\u01a1. Th\u1eadn ti\u1ebft ni\u1ec7u: ti\u1ec3u \u0111\u00eam, b\u00ed ti\u1ec3u, ti\u1ec3u nhi\u1ec1u, r\u1ed1i lo\u1ea1n ti\u1ec3u ti\u1ec7n, s\u00f3n ti\u1ec3u.<\/p>\n<p>H\u1ec7 sinh s\u1ea3n: ch\u1ea3y m\u00e1u \u00e2m \u0111\u1ea1o b\u1ea5t th\u01b0\u1eddng, r\u1ed1i lo\u1ea1n t\u00ecnh d\u1ee5c, kinh nguy\u1ec7t b\u1ea5t th\u01b0\u1eddng.<\/p>\n<p>To\u00e0n th\u00e2n: ph\u00f9 ngo\u1ea1i vi, \u1edbn l\u1ea1nh, s\u1ed1t, suy nh\u01b0\u1ee3c, kh\u00e1t.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%\">Hi\u1ebfm g\u1eb7p<\/td>\n<td style=\"width: 33.3333%\">Nhi\u1ec5m tr\u00f9ng: vi\u00eam t\u00fai th\u1eeba, vi\u00eam d\u1ea1 d\u00e0y ru\u1ed9t, vi\u00eam tai gi\u1eefa. Kh\u1ed1i u, ung th\u01b0: kh\u1ed1i u m\u1edbi.<\/p>\n<p>M\u00e1u: b\u1ec7nh h\u1ea1ch b\u1ea1ch huy\u1ebft.<\/p>\n<p>H\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch: ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, t\u0103ng cholesterol huy\u1ebft, h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<p>TKTW: l\u1ec7 thu\u1ed9c thu\u1ed1c, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n, \u00fd ngh\u0129\/h\u00e0nh vi t\u1ef1 s\u00e1t, m\u1ed9ng du, hoang t\u01b0\u1edfng, xu\u1ea5t tinh s\u1edbm, h\u00f4n m\u00ea, m\u00faa gi\u1eadt m\u00faa v\u1eddn, lo\u1ea1n v\u1eadn \u0111\u1ed9ng, t\u0103ng nh\u1eadn c\u1ea3m, r\u1ed1i lo\u1ea1n c\u1ea3m gi\u00e1c.<\/p>\n<p>M\u1eaft: t\u0103ng gl\u00f4c\u00f4m, song th\u1ecb, s\u1ee3 \u00e1nh s\u00e1ng, xu\u1ea5t huy\u1ebft ti\u1ec1n ph\u00f2ng, r\u1ed1i lo\u1ea1n ti\u1ebft n\u01b0\u1edbc m\u1eaft.<\/p>\n<p>Tim: nh\u1ed3i m\u00e1u c\u01a1 tim, lo\u1ea1n nh\u1ecbp ch\u1eadm, r\u1ed1i lo\u1ea1n tim m\u1ea1ch.<\/p>\n<p>M\u1ea1ch: thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 \u1edf ngo\u1ea1i vi, \u0111\u00e1i ra m\u00e1u.<\/p>\n<p>H\u00f4 h\u1ea5p: co th\u1eaft thanh qu\u1ea3n, th\u1edf nhanh, th\u1edf r\u00edt, kh\u1ea3n ti\u1ebfng, n\u1ea5c<\/p>\n<p>Ti\u00eau h\u00f3a: ph\u00e2n \u0111en, ph\u00e2n c\u00f3 m\u00e1u, c\u00e1c b\u1ec7nh v\u1ec1 r\u0103ng, vi\u00eam l\u01b0\u1ee1i, lo\u00e9t mi\u1ec7ng.<\/p>\n<p>Gan m\u1eadt: b\u1ea5t th\u01b0\u1eddng ch\u1ee9c n\u0103ng gan.<\/p>\n<p>Da: vi\u00eam da d\u1ecb \u1ee9ng, vi\u00eam da b\u1ecdng n\u01b0\u1edbc, m\u1ee5n tr\u1ee9ng c\u00e1 \u0111\u1ecf.<\/p>\n<p>C\u01a1 &#8211; x\u01b0\u01a1ng &#8211; kh\u1edbp: r\u1ed1i lo\u1ea1n x\u01b0\u01a1ng.<\/p>\n<p>Th\u1eadn &#8211; ti\u1ebft ni\u1ec7u: b\u00ed ti\u1ec3u, \u0111\u00e1i d\u1eaft.<\/p>\n<p>H\u1ec7 sinh s\u1ea3n: rong kinh, vi\u00eam \u00e2m \u0111\u1ea1o, vi\u00eam bao qui \u0111\u1ea7u, kh\u00ed h\u01b0 b\u1ea5t<\/p>\n<p>th\u01b0\u1eddng, c\u01b0\u01a1ng c\u1ee9ng d\u01b0\u01a1ng v\u1eadt k\u00e9o d\u00e0i, ch\u1ea3y s\u1eefa.<\/p>\n<p>To\u00e0n th\u00e2n: gi\u1ea3m dung n\u1ea1p thu\u1ed1c, tho\u00e1t v\u1ecb, thay \u0111\u1ed5i d\u00e1ng \u0111i.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%\">Ch\u01b0a x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c t\u1ea7n su\u1ea5t<\/td>\n<td style=\"width: 33.3333%\">M\u00e1u: gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u.<\/p>\n<p>Mi\u1ec5n d\u1ecbch: d\u1ecb \u1ee9ng.<\/p>\n<p>N\u1ed9i ti\u1ebft: t\u0103ng prolactin huy\u1ebft, r\u1ed1i lo\u1ea1n b\u00e0i ti\u1ebft hormon ch\u1ed1ng b\u00e0i ni\u1ec7u.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: h\u1ea1 natri huy\u1ebft, t\u0103ng glucose huy\u1ebft.<\/p>\n<p>TKTW: \u00e1c m\u1ed9ng, r\u1ed1i lo\u1ea1n v\u1eadn \u0111\u1ed9ng, h\u1ed9i ch\u1ee9ng serotonin, h\u1ed9i ch\u1ee9ng th\u1ea7n kinh \u00e1c t\u00ednh, co th\u1eaft m\u1ea1ch n\u00e3o.<\/p>\n<p>M\u1eaft: t\u1ea7m nh\u00ecn b\u1ea5t th\u01b0\u1eddng, \u0111\u1ed3ng t\u1eed kh\u00f4ng \u0111\u1ec1u.<\/p>\n<p>Tim: k\u00e9o d\u00e0i kho\u1ea3ng QT, xo\u1eafn \u0111\u1ec9nh.<\/p>\n<p>M\u1ea1ch: ch\u1ea3y m\u00e1u b\u1ea5t th\u01b0\u1eddng (xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a).<\/p>\n<p>H\u00f4 h\u1ea5p: b\u1ec7nh ph\u1ed5i m\u00f4 k\u1ebd.<\/p>\n<p>Ti\u00eau h\u00f3a: vi\u00eam t\u1ee5y.<\/p>\n<p>Gan m\u1eadt: vi\u00eam gan, v\u00e0ng da, suy gan.<\/p>\n<p>Da: c\u00e1c ph\u1ea3n \u1ee9ng tr\u00ean da n\u1eb7ng hi\u1ebfm g\u1eb7p nh\u01b0 h\u1ed9i ch\u1ee9ng Stevens- Johnson, ho\u1ea1i t\u1eed b\u00ec nhi\u1ec5m \u0111\u1ed9c, ph\u00f9 m\u1ea1ch, nh\u1ea1y s\u00e1ng, ph\u1ea3n \u1ee9ng tr\u00ean da.<\/p>\n<p>C\u01a1 &#8211; x\u01b0\u01a1ng &#8211; kh\u1edbp: co th\u1eaft c\u01a1. H\u1ec7 sinh s\u1ea3n: v\u00fa to \u1edf nam.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>H\u1ed9i ch\u1ee9ng cai thu\u1ed1c<\/h4>\n<p>H\u1ed9i ch\u1ee9ng cai thu\u1ed1c (ch\u01b0a h\u1eb3n l\u00e0 do thu\u1ed1c) x\u1ea3y ra d\u01b0\u1edbi 0,5% ng\u01b0\u1eddi \u0111i\u1ec1u tr\u1ecb sertralin.<\/p>\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng g\u1eb7p l\u00e0 h\u1ed9i ch\u1ee9ng gi\u1ed1ng c\u00fam nh\u01b0: m\u1ec7t m\u1ecfi, kh\u00f3 ch\u1ecbu \u1edf d\u1ea1 d\u00e0y (bu\u1ed3n n\u00f4n), ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u nh\u1eb9, run, lo \u00e2u, l\u1ea1nh, to\u00e1t m\u1ed3 h\u00f4i, r\u1ed1i lo\u1ea1n \u0111i\u1ec1u ph\u1ed1i.<\/p>\n<p>Ngo\u00e0i ra r\u1ed1i lo\u1ea1n tr\u00ed nh\u1edb, m\u1ea5t ng\u1ee7, d\u1ecb c\u1ea3m, nh\u1ee9c \u0111\u1ea7u, c\u1ea3m gi\u00e1c gi\u1ed1ng cho\u00e1ng, h\u1ed3i h\u1ed9p, k\u00edch \u0111\u1ed9ng. C\u00e1c ph\u1ea3n \u1ee9ng lo\u1ea1i n\u00e0y th\u01b0\u1eddng t\u1ef1 gi\u1ea3m \u0111i ho\u1eb7c \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n sau m\u1ed9t v\u00e0i tu\u1ea7n.<\/p>\n<p>\u0110\u1ec3 tr\u00e1nh h\u1ed9i ch\u1ee9ng cai thu\u1ed1c, n\u00ean gi\u1ea3m d\u1ea7n li\u1ec1u c\u1ee7a sertralin tr\u01b0\u1edbc khi ng\u1eebng thu\u1ed1c.<\/p>\n<p>C\u0169ng gi\u1ed1ng c\u00e1c thu\u1ed1c t\u00e1c d\u1ee5ng tr\u00ean h\u1ec7 TKTW kh\u00e1c, n\u00ean \u0111\u00e1nh gi\u00e1 c\u1ea9n th\u1eadn t\u00ecnh tr\u1ea1ng quen thu\u1ed1c \u1edf ng\u01b0\u1eddi b\u1ec7nh tr\u01b0\u1edbc khi d\u00f9ng sertralin.<\/p>\n<p>N\u1ebfu ng\u01b0\u1eddi b\u1ec7nh c\u00f3 ti\u1ec1n s\u1eed quen thu\u1ed1c v\u1edbi m\u1ed9t thu\u1ed1c n\u00e0o \u0111\u00f3 th\u00ec khi \u0111i\u1ec1u tr\u1ecb c\u1ea7n ph\u1ea3i gi\u00e1m s\u00e1t ch\u1eb7t ch\u1ebd c\u00e1c d\u1ea5u hi\u1ec7u quen thu\u1ed1c.<\/p>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n<p>T\u01b0\u01a1ng t\u00e1c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/p>\n<p>C\u00e1c thu\u1ed1c IMAO (selegilin, moclobemid, Linezolid): Do nguy c\u01a1 h\u1ed9i ch\u1ee9ng serotonin v\u1edbi c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 k\u00edch \u0111\u1ed9ng, run, t\u0103ng th\u00e2n nhi\u1ec7t. Tr\u00e1nh b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi sertralin trong v\u00f2ng 14 ng\u00e0y sau khi ng\u1eebng \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00e1c thu\u1ed1c IMAO. Ng\u1eebng \u0111i\u1ec1u tr\u1ecb v\u1edbi sertralin \u00edt nh\u1ea5t 7 ng\u00e0y tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00e1c thu\u1ed1c IMAO.<\/p>\n<p>Pimozid: Vi\u1ec7c ph\u1ed1i h\u1ee3p l\u00e0m t\u0103ng 35% n\u1ed3ng \u0111\u1ed9 pimozid trong m\u00e1u, do kho\u1ea3ng \u0111i\u1ec1u tr\u1ecb h\u1eb9p c\u1ee7a pimozid, tr\u00e1nh ph\u1ed1i h\u1ee3p \u0111\u1ed3ng th\u1eddi sertralin v\u00e0 pimozid.<\/p>\n<h4>Th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p<\/h4>\n<p>Th\u1eadn tr\u1ecdng ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf TKTW v\u00e0 r\u01b0\u1ee3u, c\u00e1c thu\u1ed1c t\u00e1c d\u1ee5ng l\u00ean h\u1ec7 serotonergic kh\u00e1c.<\/p>\n<p>C\u00e1c thu\u1ed1c k\u00e9o d\u00e0i kho\u1ea3ng QT: T\u0103ng nguy c\u01a1 k\u00e9o d\u00e0i kho\u1ea3ng QT v\u00e0\/ho\u1eb7c lo\u1ea1n nh\u1ecbp th\u1ea5t khi ph\u1ed1i h\u1ee3p sertralin v\u1edbi c\u00e1c thu\u1ed1c k\u00e9o d\u00e0i kho\u1ea3ng QT (c\u00e1c thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n v\u00e0 kh\u00e1ng sinh). Lithi: Ph\u1ed1i h\u1ee3p l\u00e0m t\u0103ng t\u1ef7 l\u1ec7 run c\u01a1.<\/p>\n<p>Phenytoin: Trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p ghi nh\u1eadn, c\u00f3 s\u1ef1 t\u0103ng cao b\u1ea5t th\u01b0\u1eddng n\u1ed3ng \u0111\u1ed9 Phenytoin tr\u00ean c\u00e1c b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng sertralin, do v\u1eady c\u1ea7n ki\u1ec3m so\u00e1t n\u1ed3ng \u0111\u1ed9 phenytoin trong m\u00e1u khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi sertralin, hi\u1ec7u ch\u1ec9nh li\u1ec1u phenytoin n\u1ebfu c\u1ea7n.<\/p>\n<p>C\u00e1c triptan: M\u1ed9t s\u1ed1 \u00edt nghi\u00ean c\u1ee9u \u0111\u00e3 ghi nh\u1eadn b\u1ec7nh nh\u00e2n v\u1edbi c\u00e1c d\u1ea5u hi\u1ec7u m\u1ec7t m\u1ecfi, t\u0103ng ph\u1ea3n x\u1ea1 qu\u00e1 m\u1ee9c, gi\u1ea3m ph\u1ed1i h\u1ee3p c\u00e1c \u0111\u1ed9ng t\u00e1c, l\u00fa l\u1eabn, lo \u00e2u v\u00e0 k\u00edch \u0111\u1ed9ng khi s\u1eed d\u1ee5ng ph\u1ed1i h\u1ee3p sertralin v\u00e0 Sumatriptan. C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ed9i ch\u1ee9ng serotonergic c\u0169ng x\u1ea3y ra khi ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u00f9ng nh\u00f3m triptan. C\u1ea7n gi\u00e1m s\u00e1t b\u1ec7nh nh\u00e2n khi ph\u1ed1i h\u1ee3p \u0111\u1ed3ng th\u1eddi sertralin v\u1edbi c\u00e1c thu\u1ed1c nh\u00f3m triptan.<\/p>\n<p>Warfarin: L\u00e0m t\u0103ng m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf (nh\u01b0ng c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng) th\u1eddi gian prothrombin. C\u1ea7n gi\u00e1m s\u00e1t th\u1eddi gian prothrombin khi b\u1eaft \u0111\u1ea7u ho\u1eb7c ng\u1eebng \u0111i\u1ec1u tr\u1ecb v\u1edbi sertralin.<\/p>\n<p>C\u00e1c thu\u1ed1c kh\u00e1c (digoxin, Atenolol, cimetidin): L\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 \u0111\u1ed9 thanh th\u1ea3i sertralin. Ch\u01b0a r\u00f5 \u00fd ngh\u0129a l\u00e2m s\u00e0ng c\u1ee7a thay \u0111\u1ed5i n\u00e0y. Thu\u1ed1c t\u00e1c d\u1ee5ng l\u00ean ti\u1ec3u c\u1ea7u: Nguy c\u01a1 xu\u1ea5t huy\u1ebft t\u0103ng l\u00ean khi ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c t\u00e1c d\u1ee5ng l\u00ean ti\u1ec3u c\u1ea7u (nh\u01b0 NSAID, Acid Acetylsalicylic, ticlopidin) v\u1edbi sertralin.<\/p>\n<p>C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh c\u01a1: Sertralin l\u00e0m gi\u1ea3m ho\u1ea1t t\u00ednh c\u1ee7a men cholinesterase do v\u1eady l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf th\u1ea7n kinh c\u01a1 c\u1ee7a c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh c\u01a1 nh\u01b0 mivacurium.<\/p>\n<p>C\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a b\u1edfi cytochrom P450: Sertralin t\u00e1c d\u1ee5ng nh\u01b0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh CYP2D6<\/p>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n<h4>Ph\u1ee5 n\u1eef mang thai<\/h4>\n<p>Kh\u00f4ng c\u00f3 c\u00e1c nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7 v\u00e0 \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t ch\u1eb7t ch\u1ebd \u1edf ph\u1ee5 n\u1eef mang thai. Sertraline ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai khi l\u1ee3i \u00edch c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb l\u1edbn h\u01a1n kh\u1ea3 n\u0103ng g\u00e2y r\u1ee7i ro cho thai nhi.<\/p>\n<h4>Ph\u1ee5 n\u1eef cho con b\u00fa<\/h4>\n<p>Ch\u01b0a c\u00f3 \u0111\u00e1nh gi\u00e1 ch\u00ednh x\u00e1c r\u1eb1ng sertraline c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng v\u00e0 n\u1ebfu c\u00f3 th\u00ec v\u1edbi l\u01b0\u1ee3ng bao nhi\u00eau. V\u00ec nhi\u1ec1u thu\u1ed1c b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9, c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng sertraline cho ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa.<\/p>\n<h3>\u1ea2nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0ng m\u00e1y m\u00f3c<\/h3>\n<p>C\u00e1c thu\u1ed1c h\u01b0\u1edbng th\u1ea7n n\u00f3i chung c\u00f3 th\u1ec3 l\u00e0m suy gi\u1ea3m kh\u1ea3 n\u0103ng l\u00e0m vi\u1ec7c v\u1ec1 tr\u00ed tu\u1ec7 hay c\u01a1 b\u1eafp c\u1ea7n thi\u1ebft cho nh\u1eefng c\u00f4ng vi\u1ec7c c\u00f3 nguy c\u01a1 ti\u1ec1m \u1ea9n cao nh\u01b0 l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. Do \u0111\u00f3, b\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c c\u1ea3nh b\u00e1o v\u1ec1 \u0111i\u1ec1u n\u00e0y.<\/p>\n<h3><span style=\"font-weight: 400\">B\u1ea3o qu\u1ea3n<\/span><\/h3>\n<p>B\u1ea3o qu\u1ea3n \u1edf nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30\u00b0C.<\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Utralene (Setraline) 100mg gi\u00e1 bao nhi\u00eau? mua \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Utralene-100 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Utralene-100<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c <\/span><span style=\"font-weight: 400\">Utralene-100 <\/span><span style=\"font-weight: 400\">t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f4ng d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0:\u00a0<\/span><\/p>\n<ol>\n<li><a href=\"https:\/\/vnras.com\/drug\/utralene-50\/\"> Thu\u1ed1c Utralene-50<\/a> c\u00f9ng \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Umedica Laboratories PVT. Ltd., c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-17228-13, v\u1edbi h\u00e0m l\u01b0\u1ee3ng Setraline l\u00e0 50mg hi\u1ec7u qu\u1ea3 v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi Utralene100 . H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean hi\u1ec7n c\u00f3 gi\u00e1 210,000 \u0111\u1ed3ng.<\/li>\n<li><a href=\"https:\/\/vnras.com\/drug\/serenata-100\/\">Thu\u1ed1c Serenata 100<\/a> c\u00f3 ch\u1ee9a Sertraline 100mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m ho\u1eb7c ch\u1ee9ng r\u1ed1i lo\u1ea1n \u00e1m \u1ea3nh xung l\u1ef1c c\u01b0\u1ee1ng ch\u1ebf, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Torrent Pharmaceuticals Lt\u0111 v\u1edbi s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-15151-12. H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean c\u00f3 gi\u00e1 l\u00e0 450,000.<\/li>\n<\/ol>\n<h2><span style=\"font-weight: 400\">Utralene-100 c\u00f3 t\u1ed1t kh\u00f4ng? T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn Utralene-100 ?<\/span><\/h2>\n<table style=\"width: 91.8647%\">\n<tbody>\n<tr>\n<td style=\"text-align: center;width: 66.18%\"><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"text-align: center;width: 73.864%\"><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 66.18%\">Thu\u1ed1c Utralene-100 \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf vi\u00ean n\u00e9n bao phim d\u1ec5 b\u1ea3o qu\u1ea3n, che d\u1ea5u \u0111\u01b0\u1ee3c m\u00f9i v\u1ecb kh\u00f3 ch\u1ecbu v\u00e0 d\u1ec5 s\u1eed d\u1ee5ng k\u1ec3 c\u1ea3 v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng t\u1ef1 s\u1eed d\u1ee5ng \u0111\u01b0\u1ee3c thu\u1ed1c<\/p>\n<p>Setraline cho t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m cao h\u01a1n so v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m kh\u00e1c, n\u00ean \u0111\u01b0\u1ee3c d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m n\u1eb7ng<\/p>\n<p>Ho\u1ea1t ch\u1ea5t Setraline kh\u00f4ng ch\u1ec9 c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00e1c r\u1ed1i lo\u1ea1n lo \u00e2u do h\u1ec7 th\u1ea7n kinh m\u00e0 c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng cho c\u1ea3 nh\u1eefng r\u1ed1i lo\u1ea1n li\u00ean quan \u0111\u1ebfn b\u1ec7nh l\u00fd kh\u00e1c nh\u01b0: r\u1ed1i lo\u1ea1n tr\u01b0\u1edbc k\u1ef3 kinh, r\u1ed1i lo\u1ea1n \u0103n u\u1ed1ng.<\/p>\n<p>Setraline c\u0169ng \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u cho sinh kh\u1ea3 d\u1ee5ng cao h\u01a1n, h\u1ea5p thu t\u1ed1t h\u01a1n, \u00edt t\u00e1c d\u1ee5ng ph\u1ee5, kho\u1ea3ng an to\u00e0n r\u1ed9ng v\u00e0 h\u1ea1n ch\u1ebf t\u00ecnh tr\u1ea1ng ph\u1ee5 thu\u1ed9c thu\u1ed1c<\/p>\n<p>\u0110\u01b0\u1ee3c d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh tr\u1ea7m c\u1ea3m n\u1eb7ng cho b\u1ec7nh nh\u00e2n nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p ho\u1eb7c \u0111au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh do \u00edt t\u00e1c d\u1ee5ng ph\u1ee5 l\u00ean h\u1ec7 tim m\u1ea1ch.<\/td>\n<td style=\"width: 73.864%\">Setraline ti\u1ec1m \u1ea9n kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m ti\u1ec3u c\u1ea7u v\u00e0 g\u00e2y ch\u1ea3y m\u00e1u \u1edf b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng<\/p>\n<p>T\u01b0\u01a1ng t\u1ef1 nh\u01b0 c\u00e1c thu\u1ed1c h\u01b0\u1edbng th\u1ea7n kh\u00e1c, d\u00f9ng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t c\u00f3 th\u1ec3 g\u00e2y h\u1ed9i ch\u1ee9ng ng\u01b0ng thu\u1ed1c.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\">T\u00e1c gi\u1ea3 Andrea Cipriani v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng: n\u0103m 2010) <em>Sertraline versus other antidepressive agents for depression<\/em>. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 11 n\u0103m 2023 t\u1eeb <a href=\"https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD006117.pub3\/full\" rel=\"noopener\">https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD006117.pub3\/full<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 Mathilde Strumia v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng n\u0103m 2020). <em>Platelet function defects and sertraline-induced bleeding: a case report<\/em>. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 11 n\u0103m 2023 t\u1eeb <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/fcp.12552\" rel=\"noopener\">https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/fcp.12552<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 M. Reis v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng n\u0103m 2010). <em>Delivery outcome after maternal use of antidepressant drugs in pregnancy: an update using Swedish data<\/em>. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 11 n\u0103m 2023 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20047705\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/20047705\/<\/a><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng Utralene-100 do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, xem th\u00eam <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2023\/11\/hdsd-thuoc-utralene-100-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>.<\/span><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Utralene 100 mg c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Sertraline, h\u1ed9p 10 v\u1ec9 x 10 vi\u00ean c\u1ee7a \u1ea4n \u0110\u1ed9, l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m<\/p>\n","protected":false},"author":490,"featured_media":59768,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-59766","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/59766","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=59766"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/59768"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=59766"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=59766"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=59766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}