{"id":58363,"date":"2023-11-21T23:01:56","date_gmt":"2023-11-21T16:01:56","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=58363"},"modified":"2025-07-24T13:44:12","modified_gmt":"2025-07-24T06:44:12","slug":"thuoc-xelostad-10mg-stella","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-xelostad-10mg-stella\/","title":{"rendered":"Xelostad 10mg Stella"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/thuoc-xelostad-10mg-stella\/\">Xelostad 10 Stella<\/a> v\u1edbi th\u00e0nh ph\u1ea7n 10mg Rivaroxaban; c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng \u0111\u00f4ng b\u1eb1ng c\u00e1ch g\u1eafn k\u1ebft tr\u1ef1c ti\u1ebfp v\u1edbi y\u1ebfu t\u1ed1 Xa, do Stella -Vi\u1ec7t Nam s\u1ea3n xu\u1ea5t v\u00e0 ch\u1ecbu tr\u00e1ch nhi\u1ec7m ph\u00e2n ph\u1ed1i thu\u1ed1c, d\u01b0\u1edbi s\u1ed1 l\u01b0u h\u00e0nh trong n\u01b0\u1edbc l\u00e0 VD-33894-19.\u00a0<\/b><\/p>\n<h2><span style=\"font-weight: 400\">Xelostad 10 Stella l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\"><strong>Thu\u1ed1c<\/strong> <strong>Xelostad 10 Stella<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\">Rivaroxaban: 10mg.<\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim\u00a0<\/span><\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VD-33894-19.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: Stella -Vi\u1ec7t Nam.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Xelostad 10 Stella<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng\u00a0<\/span><\/h3>\n<p>Rivaroxaban l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc cao v\u00e0 tr\u1ef1c ti\u1ebfp y\u1ebfu t\u1ed1 Xa v\u1edbi sinh kh\u1ea3 d\u1ee5ng qua \u0111\u01b0\u1eddng u\u1ed1ng. S\u1ef1 \u1ee9c ch\u1ebf y\u1ebfu t\u1ed1 Xa l\u00e0m gi\u00e1n \u0111o\u1ea1n con \u0111\u01b0\u1eddng n\u1ed9i sinh v\u00e0 ngo\u1ea1i sinh c\u1ee7a d\u00f2ng th\u00e1c \u0111\u00f4ng m\u00e1u, \u1ee9c ch\u1ebf s\u1ef1 h\u00ecnh th\u00e0nh thrombin v\u00e0 ph\u00e1t tri\u1ec3n huy\u1ebft kh\u1ed1i. Rivaroxaban kh\u00f4ng \u1ee9c ch\u1ebf thrombin (y\u1ebfu t\u1ed1 II) v\u00e0 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i v\u1edbi ti\u1ec3u c\u1ea7u.<\/p>\n<p>Th\u1eddi gian ho\u1ea1t h\u00f3a m\u1ed9t ph\u1ea7n thromboplastin (aPTT) v\u00e0 HepTest c\u0169ng b\u1ecb k\u00e9o d\u00e0i ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u d\u00f9ng; tuy nhi\u00ean kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng c\u00e1c ch\u1ec9 s\u1ed1 n\u00e0y \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u1ef1c c\u1ee7a rivaroxaban<\/p>\n<p>Trong l\u00e2m s\u00e0ng, kh\u00f4ng c\u1ea7n thi\u1ebft ph\u1ea3i theo d\u00f5i c\u00e1c th\u00f4ng s\u1ed1 \u0111\u00f4ng m\u00e1u trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb v\u1edbi rivaroxaban. Tuy nhi\u00ean, khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh tr\u00ean l\u00e2m s\u00e0ng c\u00f3 th\u1ec3 \u0111o n\u1ed3ng \u0111\u1ed9 rivaroxaban b\u1eb1ng th\u1eed nghi\u1ec7m \u0111o n\u1ed3ng \u0111\u1ed9 kh\u00e1ng y\u1ebfu t\u1ed1 Xa.<\/p>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<p>H\u1ea5p thu: Rivaroxaban \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh v\u1edbi n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a (Cmax)kho\u1ea3ng 2 &#8211; 4 gi\u1edd sau khi u\u1ed1ng thu\u1ed1c. S\u1ef1 h\u1ea5p thu theo \u0111\u01b0\u1eddng u\u1ed1ng c\u1ee7a rivaroxaban g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n v\u00e0 sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng cao (80 &#8211; 90%) \u0111\u1ed1i v\u1edbi li\u1ec1u thu\u1ed1c vi\u00ean 2,5 mg v\u00e0 10 mg, b\u1ea5t k\u1ec3 \u0111i\u1ec1u ki\u1ec7n \u0111\u00f3i hay no<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c g\u1eafn k\u1ebft cao v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng \u1edf ng\u01b0\u1eddi, kho\u1ea3ng 92 &#8211; 95%, ch\u1ee7 y\u1ebfu v\u1edbi th\u00e0nh ph\u1ea7n albumin. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 \u1edf m\u1ee9c v\u1eeba ph\u1ea3i v\u1edbi gi\u00e1 tr\u1ecb Vss kho\u1ea3ng 50 L..<\/p>\n<p>Chuy\u1ec3n h\u00f3a v\u00e0 th\u1ea3i tr\u1eeb: Kho\u1ea3ng 2\/3 li\u1ec1u rivaroxaban u\u1ed1ng v\u00e0o b\u1ecb tho\u00e1i bi\u1ebfn theo chuy\u1ec3n h\u00f3a, sau \u0111\u00f3 m\u1ed9t n\u1eeda s\u1ebd \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua th\u1eadn v\u00e0 ph\u1ea7n c\u00f2n l\u1ea1i qua ph\u00e2n. 1\/3 li\u1ec1u d\u00f9ng c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb tr\u1ef1c ti\u1ebfp qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng ho\u1ea1t ch\u1ea5t kh\u00f4ng \u0111\u1ed5i trong n\u01b0\u1edbc ti\u1ec3u, ch\u1ee7 y\u1ebfu qua b\u00e0i ti\u1ebft ch\u1ee7 \u0111\u1ecdng \u1edf th\u1eadn.<\/p>\n<p>S\u1ef1 th\u1ea3i tr\u1eeb c\u1ee7a rivaroxaban kh\u1ecfi huy\u1ebft t\u01b0\u01a1ng x\u1ea3y ra v\u1edbi th\u1eddi gian b\u00e1n th\u1ea3i t\u1eeb 5 &#8211; 9 gi\u1edd \u1edf ng\u01b0\u1eddi tr\u1ebb tu\u1ed5i v\u00e0 t\u1eeb 11 -13 gi\u1edd \u1edf ng\u01b0\u1eddi cao tu\u1ed5i.<\/p>\n<p>C\u00e1c ch\u1ec9 s\u1ed1 tr\u00ean kh\u00f4ng c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t v\u1ec1 gi\u1edbi t\u00ednh, tuy nhi\u00ean s\u1ebd c\u00f3 kh\u00e1c bi\u1ebft v\u1ec1 c\u00e2n n\u1eb7ng, ngu\u1ed3n g\u1ed1c, c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 kh\u00e1c nh\u01b0: tu\u1ed5i gi\u00e0, suy th\u1eadn\u2026<\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Xelostad 10 Stella \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p>Thu\u1ed1c Xelostad 10 Stella \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh d\u00f9ng trong tr\u01b0\u1eddng h\u1ee3p<\/p>\n<ul>\n<li>Huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT).<\/li>\n<li>Ng\u0103n ch\u1eb7n t\u00ecnh tr\u1ea1ng thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch (VTE) trong giai \u0111o\u1ea1n h\u1eadu ph\u1eabu kh\u1edbp h\u00e1ng\/kh\u1edbp g\u1ed1i.<\/li>\n<li>Thuy\u00ean t\u1eafc ph\u1ed5i (PE).<\/li>\n<li>Ng\u1eeba nguy c\u01a1 DVT v\u00e0 PE t\u00e1i ph\u00e1t \u1edf ng\u01b0\u1eddi l\u1edbn<\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng &#8211; c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Xelostad 10 Stella<\/span><\/h2>\n<h3>C\u00e1ch d\u00f9ng thu\u1ed1c Xelostad 10 Stella<\/h3>\n<p>Xelostad 10 \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n.<\/p>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n kh\u00f4ng th\u1ec3 nu\u1ed1t nguy\u00ean vi\u00ean, Xelostad 10 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c nghi\u1ec1n ra tr\u1ed9n v\u1edbi n\u01b0\u1edbc, th\u1ee9c \u0103n m\u1ec1m nh\u01b0 n\u01b0\u1edbc t\u00e1o ngay tr\u01b0\u1edbc khi d\u00f9ng v\u00e0 \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n<p>C\u00f3 th\u1ec3 nghi\u1ec1n ra c\u00f3 th\u1ec3 u\u1ed1ng qua \u1ed1ng th\u00f4ng d\u1ea1 d\u00e0y, sau khi x\u00e1c \u0111\u1ecbnh \u1ed1ng \u0111\u1eb7t ch\u00ednh x\u00e1c v\u1ecb tr\u00ed d\u1ea1 d\u00e0y. Thu\u1ed1c nghi\u1ec1n ra \u0111\u01b0\u1ee3c h\u00f2a v\u00e0o m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf n\u01b0\u1edbc cho v\u00e0o \u1ed1ng th\u00f4ng, sau \u0111\u00f3 cho th\u00eam m\u1ed9t \u00edt n\u01b0\u1edbc \u0111\u1ec3 tr\u00e1ng \u1ed1ng.<\/p>\n<h3>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Xelostad 10 Stella<\/h3>\n<p><em>Ph\u00f2ng ng\u1eeba thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch (VTE) \u1edf ng\u01b0\u1eddi l\u1edbn \u0111\u01b0\u1ee3c ph\u1eabu thu\u1eadt theo ch\u01b0\u01a1ng tr\u00ecnh thay th\u1ebf kh\u1edbp h\u00e1ng ho\u1eb7c kh\u1edbp g\u1ed1i<\/em><\/p>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 1 vi\u00ean, u\u1ed1ng 1 l\u1ea7n\/ ng\u00e0y. Li\u1ec1u kh\u1edfi \u0111\u1ea7u n\u00ean \u0111\u01b0\u1ee3c d\u00f9ng trong v\u00f2ng 6-10 gi\u1edd sau ph\u1eabu thu\u1eadt v\u1edbi \u0111i\u1ec1u ki\u1ec7n t\u00ecnh tr\u1ea1ng c\u1ea7m m\u00e1u \u0111\u00e3 \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb ph\u1ee5 thu\u1ed9c v\u00e0o nguy c\u01a1 c\u1ee7a t\u1eebng b\u1ec7nh nh\u00e2n \u0111\u1ed1i v\u1edbi thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch \u0111\u00e3 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh b\u1edfi c\u00e1c lo\u1ea1i ph\u1eabu thu\u1eadt ch\u1ec9nh h\u00ecnh.<\/p>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n sau ti\u1ebfn h\u00e0nh \u0111\u1ea1i ph\u1eabu thu\u1eadt kh\u1edbp h\u00e1ng, n\u00ean \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb trong 5 tu\u1ea7n.<\/p>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n sau ti\u1ebfn h\u00e0nh \u0111\u1ea1i ph\u1eabu thu\u1eadt kh\u1edbp g\u1ed1i, n\u00ean \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb trong 2 tu\u1ea7n<\/p>\n<p><em>\u0110i\u1ec1u tr\u1ecb huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT) v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i (PE), v\u00e0 ph\u00f2ng ng\u1eeba t\u00e1i ph\u00e1t DVT v\u00e0 PE \u1edf ng\u01b0\u1eddi l\u1edbn<\/em><\/p>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o \u0111i\u1ec1u tr\u1ecb kh\u1edfi \u0111\u1ea7u DVT ho\u1eb7c PE c\u1ea5p t\u00ednh l\u00e0 1,5 vi\u00ean\/l\u1ea7n x 2 l\u1ea7n\/ ng\u00e0y trong 3 tu\u1ea7n \u0111\u1ea7u ti\u00ean, ti\u1ebfp theo u\u1ed1ng 2 vi\u00ean x 1 l\u1ea7n\/ng\u00e0y \u0111\u1ec3 ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb v\u00e0 ph\u00f2ng ng\u1eeba t\u00e1i ph\u00e1t DVT v\u00e0 PE.<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb ng\u1eafn (\u00edt nh\u1ea5t 3 th\u00e1ng) cho b\u1ec7nh nh\u00e2n b\u1ecb DVT\/ PE b\u1ecb t\u00e1c \u0111\u1ed9ng b\u1edfi c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 l\u1edbn nh\u1ea5t th\u1eddi (nh\u01b0 \u0111\u1ea1i ph\u1eabu ho\u1eb7c ch\u1ea5n th\u01b0\u01a1ng g\u1ea7n \u0111\u00e2y).<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb d\u00e0i h\u01a1n \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n b\u1ecb DVT\/ PE kh\u00f4ng b\u1ecb t\u00e1c \u0111\u1ed9ng b\u1edfi c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 l\u1edbn nh\u1ea5t th\u1eddi ho\u1eb7c b\u1ecb DVT\/ PE kh\u00f4ng c\u00f3 y\u1ebfu t\u1ed1 kh\u1edfi ph\u00e1t ho\u1eb7c ti\u1ec1n s\u1eed b\u1ecb DVT\/ PE t\u00e1i ph\u00e1t.<\/p>\n<p><em>Khi ch\u1ec9 \u0111\u1ecbnh ph\u00f2ng ng\u1eeba k\u00e9o d\u00e0i t\u00e1i ph\u00e1t DVT v\u00e0 PE (sau khi \u0111\u00e3 ho\u00e0n th\u00e0nh \u00edt nh\u1ea5t 6 th\u00e1ng \u0111i\u1ec1u tr\u1ecb DVT\/ PE)<\/em><\/p>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 1 vi\u00ean x 1 l\u1ea7n\/ng\u00e0y<\/p>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao t\u00e1i ph\u00e1t DVT\/ PE, nh\u01b0 \u1edf b\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh k\u00e8m theo ph\u1ee9c t\u1ea1p, ho\u1eb7c b\u1ec7nh nh\u00e2n ti\u1ebfn tri\u1ec3n t\u00e1i ph\u00e1t DVT\/ PE tr\u00ean li\u1ec1u ph\u00f2ng ng\u1eeba k\u00e9o d\u00e0i 1 vi\u00ean x 1 l\u1ea7n\/ng\u00e0y, xem x\u00e9t d\u00f9ng li\u1ec1u rivaroxaban 2 vi\u00ean x 1 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb v\u00e0 l\u1ef1a ch\u1ecdn li\u1ec1u ph\u1ee5 thu\u1ed9c v\u00e0o t\u1eebng b\u1ec7nh nh\u00e2n sau khi \u0111\u00e1nh gi\u00e1 c\u1ea9n th\u1eadn l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb so v\u1edbi nguy c\u01a1 g\u00e2y ch\u1ea3y m\u00e1u.<\/p>\n<p><em>\u0110i\u1ec1u tr\u1ecb huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT) v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i (PE):<\/em><\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb ng\u00e0y 1 &#8211; 21, ch\u1ebf \u0111\u1ed9 li\u1ec1u: 1,5 vi\u00ean\/l\u1ea7n x 2 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb ng\u00e0y 22 tr\u1edf \u0111i, ch\u1ebf \u0111\u1ed9 li\u1ec1u: 2 vi\u00ean x 1 l\u1ea7n\/ng\u00e0y<\/p>\n<p><em>Ph\u00f2ng ng\u1eeba t\u00e1i ph\u00e1t DVT v\u00e0 PE<\/em><\/p>\n<p>Sau khi ho\u00e0n th\u00e0nh \u0111i\u1ec1u tr\u1ecb \u00edt nh\u1ea5t 6 th\u00e1ng, ch\u1ebf \u0111\u1ed9 li\u1ec1u: 1 vi\u00ean x 1 l\u00e0n\/ng\u00e0y ho\u1eb7c 2 vi\u00ean x 1 l\u1ea7n\/ng\u00e0y<\/p>\n<p>N\u1ebfu b\u1ec7nh nh\u00e2n qu\u00ean u\u1ed1ng 1 li\u1ec1u 1,5 vi\u00ean trong ch\u1ebf \u0111\u1ed9 li\u1ec1u 2 l\u1ea7n\/ng\u00e0y (ng\u00e0y 1 &#8211; 21):<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n n\u00ean d\u00f9ng rivaroxaban ngay \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o 3 vi\u00ean\/ng\u00e0y.<\/li>\n<li>Trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y, c\u00f3 th\u1ebf u\u1ed1ng 3 vi\u00ean c\u00f9ng m\u1ed9t l\u00fac, v\u00e0 ng\u00e0y h\u00f4m sau ti\u1ebfp t\u1ee5c u\u1ed1ng 1,5 vi\u00ean \u0111\u1ec1u \u0111\u1eb7n ng\u00e0y 2 l\u1ea7n nh\u01b0 th\u01b0\u1eddng l\u1ec7.<\/li>\n<\/ul>\n<p>N\u1ebfu b\u1ec7nh nh\u00e2n qu\u00ean 1 li\u1ec1u thu\u1ed1c trong ch\u1ebf \u0111\u1ed9 li\u1ec1u 1 l\u1ea7n\/ng\u00e0y, ph\u1ea3i u\u1ed1ng li\u1ec1u rivaroxaban ngay khi nh\u1edb ra v\u00e0 ng\u00e0y h\u00f4m sau ph\u1ea3i ti\u1ebfp t\u1ee5c u\u1ed1ng thu\u1ed1c 1 l\u1ea7n\/ng\u00e0y nh\u01b0 khuy\u1ebfn c\u00e1o. Kh\u00f4ng n\u00ean d\u00f9ng li\u1ec1u g\u1ea5p \u0111\u00f4i trong c\u00f9ng 1 ng\u00e0y \u0111\u1ec3 b\u00f9 li\u1ec1u \u0111\u00e3 quen.<\/p>\n<p>Khuy\u1ebfn c\u00e1o: N\u00ean ch\u1ecdn vi\u00ean thu\u1ed1c c\u00f3 ch\u1ee9a 15mg rivaroxaban \u0111\u1ec3 ph\u00f9 h\u1ee3p cho s\u1eed d\u1ee5ng 1 l\u1ea7n.<\/p>\n<p><em>Chuy\u1ec3n \u0111\u1ed5i t\u1eeb c\u00e1c ch\u1ea5t \u0111\u1ed1i kh\u00e1ng vitamin K (VKA) sang Xelostad 10: <\/em><\/p>\n<p>Khi b\u1ec7nh nh\u00e2n chuy\u1ec3n \u0111\u1ed5i t\u1eeb VKA sang Xelostad 10, c\u00e1c gi\u00e1 tr\u1ecb INR s\u1ebd t\u0103ng gi\u1ea3 t\u1ea1o sau khi u\u1ed1ng Xelostad 10. INR n\u00e0y kh\u00f4ng c\u00f3 gi\u00e1 tr\u1ecb \u0111\u1ec3 \u0111o ho\u1ea1t t\u00ednh ch\u1ed1ng \u0111\u00f4ng c\u1ee7a Xelostad 10, v\u00ec v\u1eady kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng gi\u00e1 tr\u1ecb n\u00e0y.<\/p>\n<p><em>Chuy\u1ec3n \u0111\u1ed5i t\u1eeb Xelostad 10 sang c\u00e1c ch\u1ea5t \u0111\u1ed1i kh\u00e1ng vitamin K (VKA):<\/em><\/p>\n<p>Trong qu\u00e1 tr\u00ecnh chuy\u1ec3n \u0111\u1ed5i t\u1eeb Xelostad 10 sang VKA<\/p>\n<ul>\n<li>C\u00f3 th\u1ec3 x\u1ea3y ra t\u00ecnh tr\u1ea1ng kh\u00e1ng \u0111\u00f4ng kh\u00f4ng \u0111\u1ea7y \u0111\u1ee7.<\/li>\n<li>C\u1ea7n \u0111\u1ea3m b\u1ea3o t\u00ecnh tr\u1ea1ng kh\u00e1ng \u0111\u00f4ng \u0111\u1ea7y \u0111\u1ee7, li\u00ean t\u1ee5c trong qu\u00e1 tr\u00ecnh chuy\u1ec3n \u0111\u1ed5i sang thu\u1ed1c kh\u00e1ng \u0111\u00f4ng thay th\u1ebf.<\/li>\n<li>L\u01b0u \u00fd r\u1eb1ng Xelostad 10 c\u00f3 th\u1ec3 g\u00f3p ph\u1ea7n v\u00e0o vi\u1ec7c l\u00e0m cho gi\u00e1 tr\u1ecb INR t\u0103ng l\u00ean.<\/li>\n<\/ul>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n chuy\u1ec3n \u0111\u1ed5i t\u1eeb Xelostad 10 sang VKA:<\/p>\n<ul>\n<li>N\u00ean d\u00f9ng \u0111\u1ed3ng th\u1eddi VKA cho t\u1edbi khi INR \u2265 2,0.<\/li>\n<li>Trong hai ng\u00e0y \u0111\u1ea7u c\u1ee7a th\u1eddi gian chuy\u1ec3n \u0111\u1ed5i, n\u00ean s\u1eed d\u1ee5ng li\u1ec1u VKA ti\u00eau chu\u1ea9n, ti\u1ebfp \u0111\u1ebfn l\u00e0 li\u1ec1u VKA d\u1ef1a tr\u00ean x\u00e9t nghi\u1ec7m INR.<\/li>\n<li>Trong tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n d\u00f9ng c\u1ea3 Xelostad 10 v\u00e0 VKA, kh\u00f4ng n\u00ean x\u00e9t nghi\u1ec7m INR tr\u01b0\u1edbc 24 gi\u1edd sau li\u00eau tr\u01b0\u1edbc \u0111\u00f3 ho\u1eb7c tr\u01b0\u1edbc khi d\u00f9ng li\u1ec1u ti\u1ebfp theo c\u1ee7a Xelostad 10.<\/li>\n<li>M\u1ed9t khi Xelostad 10 b\u1ecb gi\u00e1n \u0111o\u1ea1n, c\u00f3 th\u1ec3 ti\u1ebfn h\u00e0nh x\u00e9t nghi\u1ec7m INR v\u1edbi m\u1ee9c \u0111\u1ed9 \u0111\u00e1ng tin c\u1eady trong 24 gi\u1edd sau li\u1ec1u d\u00f9ng cu\u1ed1i c\u00f9ng.<\/li>\n<\/ul>\n<p><em>Chuy\u1ec3n \u0111\u1ed5i t\u1eeb c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u \u0111\u01b0\u1eddng ti\u00eam sang Xelostad 10<\/em><\/p>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u \u0111\u01b0\u1eddng ti\u00eam, ng\u01b0ng d\u00f9ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng v\u00e0 b\u1eaft \u0111\u1ea7u Xelostad 10 t\u1eeb 0 &#8211; 2 gi\u1edd tr\u01b0\u1edbc th\u1eddi gian d\u00f9ng ti\u1ebfp theo c\u1ee7a thu\u1ed1c ti\u00eam (v\u00ed d\u1ee5 heparin c\u00f3 tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed th\u1ea5p) ho\u1eb7c t\u1ea1i th\u1eddi \u0111i\u1ec3m ng\u1eebng c\u1ee7a m\u1ed9t lo\u1ea1i thu\u1ed1c ti\u00eam s\u1eed d\u1ee5ng li\u00ean t\u1ee5c (v\u00ed d\u1ee5 ti\u00eam t\u0129nh m\u1ea1ch heparin kh\u00f4ng ph\u00e2n \u0111o\u1ea1n).<\/p>\n<p><em>Chuy\u1ec3n \u0111\u1ed5i t\u1eeb Xelostad 10 sang c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u \u0111\u01b0\u1eddng ti\u00eam<\/em><\/p>\n<p>Ti\u00eam thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u li\u1ec1u \u0111\u1ea7u ti\u00ean v\u00e0o th\u1eddi \u0111i\u1ec3m d\u00f9ng li\u1ec1u Xelostad 10 ti\u1ebfp theo.<\/p>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Xelostad 10 Stella trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p>Qu\u00e1 m\u1eabn v\u1edbi c\u00e1c th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c.<\/p>\n<p>Ch\u1ea3y m\u00e1u c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng \u0111\u00e1ng k\u1ec3.<\/p>\n<p>C\u00f3 t\u1ed5n th\u01b0\u01a1ng ho\u1eb7c c\u00f3 b\u1ec7nh l\u00fd, n\u1ebfu \u0111\u01b0\u1ee3c xem l\u00e0 m\u1ed9t nguy c\u01a1 ch\u1ea3y m\u00e1u nghi\u00eam tr\u1ecdng. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 bao g\u1ed3m \u0111ang ho\u1eb7c g\u1ea7n \u0111\u00e2y b\u1ecb lo\u00e9t \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, xu\u1ea5t hi\u1ec7n kh\u1ed1i u \u00e1c t\u00ednh v\u1edbi nguy c\u01a1 ch\u1ea3y m\u00e1u cao, g\u1ea7n \u0111\u00e2y c\u00f3 t\u1ed5n th\u01b0\u01a1ng n\u00e3o ho\u1eb7c c\u1ed9t s\u1ed1ng, g\u1ea7n \u0111\u00e2y c\u00f3 ph\u1eabu thu\u1eadt n\u00e3o, c\u1ed9t s\u1ed1ng ho\u1eb7c m\u1eaft, xu\u1ea5t huy\u1ebft n\u1ed9i s\u1ecd g\u1ea7n \u0111\u00e2y, bi\u1ebft ho\u1eb7c nghi ng\u1edd gi\u00e3n t\u0129nh m\u1ea1ch th\u1ef1c qu\u1ea3n, d\u1ecb d\u1ea1ng \u0111\u1ed9ng t\u0129nh m\u1ea1ch, ph\u00ecnh \u0111\u1ed9ng m\u1ea1ch ch\u1ee7, c\u00e1c b\u1ea5t th\u01b0\u1eddng m\u1ea1ch m\u00e1u l\u1edbn trong c\u1ed9t s\u1ed1ng ho\u1eb7c n\u1ed9i s\u1ecd.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u kh\u00e1c nh\u01b0 heparin kh\u00f4ng ph\u00e2n \u0111o\u1ea1n (UFH), heparin tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed th\u1ea5p (enoxaparin, dalteparin, &#8230;) c\u00e1c d\u1eabn xu\u1ea5t heparin (fondaparinux,&#8230;), thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u d\u1ea1ng u\u1ed1ng (warfarin, dabigatran etexilate, apixaban,&#8230;) tr\u1eeb c\u00e1c tr\u01b0\u1eddng h\u1ee3p \u0111\u1eb7c bi\u1ec7t trong li\u1ec7u tr\u00ecnh chuy\u1ec3n \u0111\u1ed5i thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng ho\u1eb7c khi UFH \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u1edf li\u1ec1u c\u1ea7n thi\u1ebft \u0111\u1ec3 b\u1ec7nh duy tr\u00ec catheter \u0111\u1ed9ng ho\u1eb7c t\u0129nh m\u1ea1ch trung t\u00e2m m\u1edf.<\/p>\n<p>B\u1ec7nh gan c\u00f3 k\u00e8m v\u1edbi b\u1ec7nh \u0111\u00f4ng m\u00e1u v\u00e0 nguy c\u01a1 ch\u1ea3y m\u00e1u c\u00f3 li\u00ean quan v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng bao g\u1ed3m c\u1ea3 nh\u1eefng b\u1ec7nh nh\u00e2n x\u01a1 gan lo\u1ea1i Child Pugh B v\u00e0 C.<\/p>\n<p>Ph\u1ee5 n\u1eef mang thai v\u00e0 cho con b\u00fa<\/p>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Xelostad 10 Stella<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<p><em>Nguy c\u01a1 xu\u1ea5t huy\u1ebft:<\/em><\/p>\n<p>C\u1ea7n ch\u00fa \u00fd khi d\u00f9ng cho b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 xu\u1ea5t huy\u1ebft cao. L\u1eadp t\u1ee9c d\u1eebng thu\u1ed1c khi x\u1ea3y ra m\u1ea5t m\u00e1u tr\u1ea7m tr\u1ecdng.<\/p>\n<p>Ch\u1ea3y m\u00e1u ni\u00eam m\u1ea1ch, thi\u1ebfu m\u00e1u x\u1ea3y ra \u1edf Xelostad nhi\u1ec1u h\u01a1n so v\u1edbi VKA.<\/p>\n<p>Th\u01b0\u1eddng xuy\u00ean ki\u1ec3m tra sinh l\u00fd m\u00e1u, n\u1ebfu th\u1ea5y gi\u1ea3m hemoglobin b\u1ea5t th\u01b0\u1eddng ph\u1ea3i l\u1eadp t\u1ee9c t\u00ecm \u0111\u01b0\u1ee3c n\u01a1i xu\u1ea5t huy\u1ebft.<\/p>\n<p><em>Suy th\u1eadn:<\/em><\/p>\n<p>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Xelostad 10 cho nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 Clcr 15-29ml\/ph\u00fat, d\u01b0\u1edbi 15ml\/ph\u00fat th\u00ec tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng thu\u1ed1c.<\/p>\n<p>Khi d\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c, c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Rivaroxaban \u1edf ng\u01b0\u1eddi c\u00f3 Clcr 30-49ml\/ph\u00fat.<\/p>\n<p><em>B\u1ec7nh nh\u00e2n d\u00f9ng van tim nh\u00e2n t\u1ea1o<\/em><\/p>\n<p>T\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a Xelostad 10 ch\u01b0a \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp. Do \u0111\u00f3, kh\u00f4ng c\u00f3 d\u1eef li\u1ec7u cho th\u1ea5y Xelostad 10 \u0111em l\u1ea1i s\u1ef1 ch\u1ed1ng \u0111\u00f4ng \u0111\u1ea7y \u0111\u1ee7 cho nh\u00f3m b\u1ec7nh nh\u00e2n n\u00e0y. Kh\u00f4ng d\u00f9ng Xelostad 10 cho nh\u00f3m b\u1ec7nh nh\u00e2n n\u00e0y<\/p>\n<p><em>Ph\u1eabu thu\u1eadt g\u00e3y x\u01b0\u01a1ng kh\u1edbp h\u00e1ng<\/em><\/p>\n<p>Rivaroxaban ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng can thi\u1ec7p \u1edf b\u1ec7nh nh\u00e2n ph\u1eabu thu\u1eadt g\u00e3y x\u01b0\u01a1ng kh\u1edbp h\u00e1ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 t\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3.<\/p>\n<p><em>G\u00e2y t\u00ea t\u1ee7y s\u1ed1ng\/ ngo\u00e0i m\u00e0ng c\u1ee9ng ho\u1eb7c ch\u1ecdc d\u00f2 t\u1ee7y s\u1ed1ng<\/em><\/p>\n<p>Kh\u00f4ng \u0111\u01b0\u1ee3c r\u00fat catheter ngo\u00e0i m\u00e0ng c\u1ee9ng s\u1edbm h\u01a1n 18 gi\u1edd sau khi d\u00f9ng li\u1ec1u rivaroxaban cu\u1ed1i c\u00f9ng. Sau khi r\u00fat catheter, \u00edt nh\u1ea5t 6 gi\u1edd sau \u0111\u00f3 m\u1edbi d\u00f9ng rivaroxaban li\u1ec1u ti\u1ebfp theo. N\u1ebfu x\u1ea3y ra t\u1ed5n th\u01b0\u01a1ng do ch\u1ecdc d\u00f2, c\u1ea7n tr\u00ec ho\u00e3n vi\u1ec7c s\u1eed d\u1ee5ng rivaroxaban t\u1edbi 24 gi\u1edd<\/p>\n<p><em>Li\u1ec1u khuy\u1ebfn c\u00e1o tr\u01b0\u1edbc v\u00e0 sau th\u1ee7 thu\u1eadt x\u00e2m l\u1ea5n, can thi\u1ec7p ph\u1eabu thu\u1eadt kh\u00e1c ngo\u00e0i th\u1ee7 thu\u1eadt thay th\u1ebf kh\u1edbp h\u00e1ng v\u00e0 kh\u1edbp g\u1ed1i:<\/em><\/p>\n<p>N\u1ebfu c\u1ea7n ph\u1ea3i l\u00e0m ph\u1eabu thu\u1eadt ho\u1eb7c th\u1ee7 thu\u1eadt x\u00e2m l\u1ea5n, n\u00ean ng\u1eebng u\u1ed1ng Xelostad 10 tr\u01b0\u1edbc ph\u1eabu thu\u1eadt \u00edt nh\u1ea5t 24 gi\u1edd, n\u1ebfu c\u00f3 th\u1ec3 ho\u1eb7c d\u1ef1a tr\u00ean \u0111\u00e1nh gi\u00e1 l\u00e2m s\u00e0ng c\u1ee7a b\u00e1c s\u0129.<\/p>\n<p>N\u1ebfu kh\u00f4ng th\u1ec3 tr\u00ec ho\u00e3n ph\u1eabu thu\u1eadt, c\u1ea7n \u0111\u00e1nh gi\u00e1 nguy c\u01a1 t\u0103ng ch\u1ea3y m\u00e1u so v\u1edbi m\u1ee9c \u0111\u1ed9 kh\u1ea9n c\u1ea5p c\u1ee7a can thi\u1ec7p.<\/p>\n<p>Sau th\u1ee7 thu\u1eadt x\u00e2m l\u1ea5n ho\u1eb7c can thi\u1ec7p ph\u1eabu thu\u1eadt, c\u1ea7n ti\u1ebfp t\u1ee5c d\u00f9ng l\u1ea1i Xelostad 10 c\u00e0ng s\u1edbm c\u00e0ng t\u1ed1t khi t\u00ecnh tr\u1ea1ng l\u00e2m s\u00e0ng cho ph\u00e9p v\u00e0 khi c\u1ea7m m\u00e1u \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp theo quy\u1ebft \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Xelostad 10 c\u00f3 ch\u1ee9a t\u00e1 d\u01b0\u1ee3c lactose. Kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c n\u00e0y cho b\u1ec7nh nh\u00e2n c\u00f3 c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 di truy\u1ec1n hi\u1ebfm g\u1eb7p kh\u00f4ng dung n\u1ea1p galactose, thi\u1ebfu h\u1ee5t enzym lactase to\u00e0n ph\u1ea7n hay k\u00e9m h\u1ea5p thu glucose-galactose<\/p>\n<p><span style=\"font-size: 20.16px;color: #333333\">T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/p>\n<table style=\"border-collapse: collapse;width: 100%;height: 214px\">\n<tbody>\n<tr style=\"height: 20px\">\n<td style=\"width: 33.3333%;height: 20px\">Th\u01b0\u1eddng g\u1eb7p<\/td>\n<td style=\"width: 33.3333%;height: 20px\">\u00cdt g\u1eb7p<\/td>\n<td style=\"width: 33.3333%;height: 20px\">Hi\u1ebfm g\u1eb7p<\/td>\n<\/tr>\n<tr style=\"height: 194px\">\n<td style=\"width: 33.3333%;height: 194px\">M\u00e1u, b\u1ea1ch huy\u1ebft: thi\u1ebfu m\u00e1u<\/p>\n<p>Th\u1ea7n kinh: hoa m\u1eaft, ch\u00f3ng m\u1eb7t<\/p>\n<p>M\u1eaft: m\u1eaft c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng xu\u1ea5t huy\u1ebft<\/p>\n<p>H\u00f4 h\u1ea5p, l\u1ed3ng ng\u1ef1c: ch\u1ea3y m\u00e1u cam<\/p>\n<p>Ti\u00eau h\u00f3a: kh\u00f3 ti\u00eau, bu\u1ed3n n\u00f4n, t\u00e1o b\u00f3n<\/td>\n<td style=\"width: 33.3333%;height: 194px\">M\u00e1u, b\u1ea1ch huy\u1ebft: t\u0103ng ti\u1ec3u c\u1ea7u<\/p>\n<p>Mi\u1ec5n d\u1ecbch: ban da, m\u1ea9n ng\u1ee9a<\/p>\n<p>Th\u1ea7n kinh: Xu\u1ea5t huy\u1ebft n\u00e3o, ng\u1ea5t<\/p>\n<p>Tim: nh\u1ecbp nhanh<\/p>\n<p>M\u1ea1ch m\u00e1u: t\u1ee5t \u00e1p huy\u1ebft, m\u00e1u t\u1ee5<\/p>\n<p>Ti\u00eau h\u00f3a: mi\u1ec7ng kh\u00f4<\/p>\n<p>Gan-m\u1eadt: suy gan<\/p>\n<p>C\u01a1-x\u01b0\u01a1ng-m\u00f4: t\u1ee5 m\u00e1u kh\u1edbp<\/td>\n<td style=\"width: 33.3333%;height: 194px\">Gan-m\u1eadt: v\u00e0ng da<\/p>\n<p>C\u01a1-x\u01b0\u01a1ng-m\u00f4: xu\u1ea5t huy\u1ebft c\u01a1<\/p>\n<p>To\u00e0n th\u00e2n: ph\u00f9 c\u1ee5c b\u1ed9<\/p>\n<p><em>Kh\u00f4ng r\u00f5 t\u1ea7n su\u1ea5t<\/em><\/p>\n<p>C\u01a1-x\u01b0\u01a1ng-m\u00f4: H\u1ed9i ch\u1ee9ng ch\u00e8n \u00e9p khoang g\u00e2y xu\u1ea5t huy\u1ebft<\/p>\n<p>Th\u00e2n-ti\u1ebft ni\u00eau: suy th\u1eadn c\u1ea5p do xu\u1ea5t huy\u1ebft l\u00e0m gi\u1ea3m t\u01b0\u1edbi m\u00e1u \u0111\u1ebfn th\u1eadn<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n<p><em>Thu\u1ed1c \u1ee9c ch\u1ebf CYP 3A4 v\u00e0 P-gp<\/em>: D\u00f9ng \u0111\u1ed3ng th\u1eddi rivaroxaban v\u1edbi ketoconazole (400 mg x 1 l\u1ea7n\/ng\u00e0y) ho\u1eb7c ritonavir (600 mg x 2 l\u1ea7n\/ng\u00e0y) l\u00e0m t\u0103ng AUC trung b\u00ecnh c\u1ee7a rivaroxaban l\u00ean 2,6\/ 2,5 l\u1ea7n v\u00e0 Cmax trung b\u00ecnh c\u1ee7a rivaroxaban t\u0103ng l\u00ean 1,7\/1,6 l\u1ea7n, \u0111\u1ed3ng th\u1eddi t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u1ef1c c\u0169ng t\u0103ng l\u00ean \u0111\u00e1ng k\u1ec3 d\u1eabn t\u1edbi nguy c\u01a1 ch\u1ea3y m\u00e1u c\u0169ng gia t\u0103ng. V\u00ec v\u1eady, khuy\u1ebfn c\u00e1o kh\u00f4ng s\u1eed d\u1ee5ng Xelostad 10 \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng n\u1ea5m azole nh\u01b0 ketoconazole, itraconazole, voriconazole v\u00e0 posaconazole ho\u1eb7c c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf HIV protease. \u0110\u00e2y l\u00e0 nh\u1eefng thu\u1ed1c \u1ee9c ch\u1ebf Cmax m\u1ea1nh CYP 3A4 v\u00e0 P-gp.<\/p>\n<p><em>Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u:<\/em> Khi d\u00f9ng ph\u1ed1i h\u1ee3p enoxaparin (40 mg li\u1ec1u duy nh\u1ea5t) v\u1edbi rivaroxaban (10 mg li\u1ec1u duy nh\u1ea5t), \u0111\u00e3 nh\u1eadn th\u1ea5y c\u00f3 t\u00e1c d\u1ee5ng c\u1ed9ng th\u00eam tr\u00ean ho\u1ea1t t\u00ednh kh\u00e1ng y\u1ebfu t\u1ed1 Xa nh\u01b0ng l\u1ea1i kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ed9ng th\u00eam n\u00e0o tr\u00ean x\u00e9t nghi\u1ec7m \u0111\u00f4ng m\u00e1u (PT, aPTT). Enoxaparin kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a rivaroxaban. Nguy c\u01a1 ch\u1ea3y m\u00e1u s\u1ebd t\u0103ng l\u00ean n\u1ebfu \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi b\u1ea5t k\u1ef3 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng n\u00e0o kh\u00e1c.<\/p>\n<p><em>NSAID\/ thu\u1ed1c \u1ee9c ch\u1ebf k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u:<\/em> C\u1ea7n gi\u00e1m s\u00e1t ch\u1eb7t ch\u1ebd b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c NSAID (bao g\u1ed3m acetylsalicylic acid) v\u00e0 c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u v\u00ec \u0111\u00e2y l\u00e0 nh\u1eefng thu\u1ed1c \u0111i\u1ec3n h\u00ecnh l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/p>\n<p><em>SSRIs\/SNRIs:<\/em> Gi\u1ed1ng v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng kh\u00e1c, nguy c\u01a1 ch\u1ea3y m\u00e1u t\u0103ng l\u00ean n\u1ebfu \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi SSRIs\/SNRIs, do \u1ea3nh h\u01b0\u1edfng \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y tr\u00ean ti\u1ec3u c\u1ea7u.<\/p>\n<p><em>Warfarin:<\/em> Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc gi\u1eefa warfarin v\u1edbi rivaroxaban.<\/p>\n<p><em>Thu\u1ed1c c\u1ea3m \u1ee9ng CYP3A4:<\/em> D\u00f9ng \u0111\u1ed3ng th\u1eddi rivaroxaban v\u1edbi thu\u1ed1c c\u1ea3m \u1ee9ng CYP3A4 m\u1ea1nh nh\u01b0 rifampicin, l\u00e0m gi\u1ea3m kho\u1ea3ng 50% AUC trung b\u00ecnh c\u1ee7a rivaroxaban, \u0111\u1ed3ng th\u1eddi l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u1ef1c c\u1ee7a thu\u1ed1c. S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi rivaroxaban v\u1edbi c\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng CYP3A4 m\u1ea1nh kh\u00e1c (nh\u01b0 phenytoin carbamazepine, phenobarbital hay St. John&#8217;s Wort (Hypericum perforatum)) c\u0169ng c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 rivaroxaban trong huy\u1ebft t\u01b0\u01a1ng. Do \u0111\u00f3, n\u00ean tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng CYP3A4 m\u1ea1nh tr\u1eeb khi b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng c\u1ee7a huy\u1ebft kh\u1ed1i.<\/p>\n<p><em>Rivaroxaban<\/em> kh\u00f4ng \u1ee9c ch\u1ebf c\u0169ng kh\u00f4ng c\u1ea3m \u1ee9ng b\u1ea5t k\u1ef3 \u0111\u1ed3ng ph\u00e2n CYP ch\u00ednh n\u00e0o nh\u01b0 CYP3A4.<\/p>\n<p>Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c n\u00e0o li\u00ean quan \u0111\u1ebfn l\u00e2m s\u00e0ng v\u1edbi th\u1ef1c ph\u1ea9m<\/p>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n<p>Ch\u01b0a s\u1ed1 li\u1ec7u nghi\u00ean c\u1ee9u \u0111\u1ea7y cho v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng Rivaroxaban c\u00f3 \u1ea3nh h\u01b0\u1edfng th\u1ebf n\u00e0o \u0111\u1ebfn m\u1eb9 b\u1ea7u v\u00e0 ng\u01b0\u1eddi \u0111ang cho con b\u00fa n\u00ean c\u1ea7n c\u1ea9n tr\u1ecdng khi s\u1eed d\u1ee5ng. Tham v\u1ea5n \u00fd ki\u1ebfn c\u1ee7a b\u00e1c s\u0129 \u0111\u1ec3 c\u00e2n nh\u1eafc l\u1ee3i \u00edch v\u00e0 t\u00e1c h\u1ea1i khi d\u00f9ng thu\u1ed1c.<\/p>\n<h3><span style=\"font-weight: 400\">\u1ea2nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/span><\/h3>\n<p>\u00cdt c\u00f3 \u1ea3nh h\u01b0\u1edfng. Tuy nhi\u00ean c\u0169ng \u0111\u00e3 c\u00f3 m\u1ed9t v\u00e0i b\u00e1o c\u00e1o v\u1ec1 c\u00e1c tri\u1ec7u ch\u1ee9ng x\u1ea3y ra sau khi u\u1ed1ng Xelostad nh\u01b0: ng\u1ea5t, hoa m\u1eaft, \u0111au \u0111\u1ea7u.<\/p>\n<p>Kh\u00f4ng v\u1eadn h\u00e0nh xe hay m\u00e1y m\u00f3c khi g\u1eb7p b\u1ea5t c\u1ee9 m\u1ed9t tri\u1ec7u ch\u1ee9ng n\u00e0o k\u1ec3 tr\u00ean.<\/p>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p>M\u1ed9t s\u1ed1 \u00edt tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u l\u00ean \u0111\u1ebfn 600 mg \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o kh\u00f4ng c\u00f3 bi\u1ebfn ch\u1ee9ng ch\u1ea3y m\u00e1u ho\u1eb7c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i kh\u00e1c.<\/p>\n<p>Do s\u1ef1 h\u1ea5p thu b\u1ecb h\u1ea1n ch\u1ebf, n\u00ean hi\u1ec7u qu\u1ea3 \u1edf m\u1ee9c t\u1ed1i \u0111a m\u00e0 kh\u00f4ng t\u0103ng th\u00eam m\u1ee9c ti\u1ebfp x\u00fac trung b\u00ecnh trong huy\u1ebft t\u01b0\u01a1ng c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf li\u1ec1u tr\u00ean li\u1ec1u \u0111i\u1ec1u tr\u1ecb \u2265 50 mg.<\/p>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng than ho\u1ea1t t\u00ednh l\u00e0m gi\u1ea3m h\u1ea5p thu trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u rivaroxaban c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c xem x\u00e9t. Do rivaroxaban g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng cao n\u00ean c\u00f3 th\u1ec3 kh\u00f4ng th\u1ea9m t\u00e1ch \u0111\u01b0\u1ee3c<\/p>\n<p>X\u1eed l\u00fd ch\u1ea3y m\u00e1u:<\/p>\n<ul>\n<li>Ho\u00e3n ho\u1eb7c ng\u1eebng thu\u1ed1c cho \u0111\u1ebfn khi gi\u1ea3i quy\u1ebft \u0111\u01b0\u1ee3c nguy c\u01a1 xu\u1ea5t huy\u1ebft (x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c v\u1ecb tr\u00ed, \u1ed5n \u0111\u1ecbnh d\u00f2ng m\u00e1u).<\/li>\n<li>D\u00f9ng ch\u1ea5t \u0111\u1eb7c hi\u1ec7u ch\u1ed1ng \u0111\u00f4ng (PCC, APCC, r-FVIIa) n\u1ebfu kh\u00f4ng th\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c s\u1ef1 ch\u1ea3y m\u00e1u.<\/li>\n<li>Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i tr\u1eeb \u0111\u1eb7c hi\u1ec7u rivaroxaban..<\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">B\u1ea3o qu\u1ea3n<\/span><\/h3>\n<p>B\u1ea3o qu\u1ea3n rivaroxaban trong h\u1ed9p k\u00edn, \u0111\u1ec3 n\u01a1i tho\u00e1ng m\u00e1t, xa t\u1ea7m v\u1edbi c\u1ee7a tr\u1ebb em, nhi\u1ec7t \u0111\u1ed9 b\u1ea3o qu\u1ea3n &lt; 30 \u2103<\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Xelostad 10 Stella gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Xelostad 10 Stella hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Xelostad 10 Stella<\/strong>\u00a0c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Xelostad 10 Stella t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Xelostad 10 Stella nh\u01b0:\u00a0<\/span><\/p>\n<ol>\n<li><a href=\"https:\/\/vnras.com\/drug\/xarelto\/\">Thu\u1ed1c Xarelto<\/a> \u0111\u01b0\u1ee3c sa\u0309n xu\u00e2\u0301t b\u01a1\u0309i c\u00f4ng ty Bayer Pharma AG \u2013 \u0110\u1ee8C c\u00f3 s\u00f4\u0301 \u0111\u0103ng ki\u0301: VN-19014-15 v\u1edbi th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Rivaroxaban 10mg; \u0111\u01b0\u01a1c d\u00f9ng d\u00f9ng trong vi\u1ec7c ph\u00f2ng ng\u1eeba \u0111\u1ed9t qu\u1ef5 v\u00e0 \u0111i\u1ec1u tr\u1ecb huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u. M\u1ed7i h\u1ed9p g\u1ed3m 14 vi\u00ean n\u00e9n Xarelto c\u00f3 gi\u00e1 970.000 \u0111\u1ed3ng\/ h\u1ed9p<\/li>\n<\/ol>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Xelostad 10 Stella?<\/span><\/h2>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 60.308%;text-align: center\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 39.692%;text-align: center\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 60.308%\">Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u, ph\u00f2ng ng\u1eeba huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i h\u1eadu ph\u1eabu \u0111i\u1ec1u tr\u1ecb thay th\u1ebf kh\u1edbp h\u00e1ng, kh\u1edbp g\u1ed1i.<\/p>\n<p>Rivaroxaban l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn kh\u1ea3 thi khi c\u1ea7n d\u00f9ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc c\u1ea3 b\u1ec7nh tim m\u1ea1ch v\u00e0 suy th\u1eadn.<\/p>\n<p>\u0110\u00e2y l\u00e0 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1eddng u\u1ed1ng t\u00e1c d\u1ee5ng tr\u1ef1c ti\u1ebfp \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn \u0111\u1ec3 ng\u0103n ng\u1eeba \u0111\u1ed9t qu\u1ef5 \u1edf b\u1ec7nh nh\u00e2n rung t\u00e2m nh\u0129.<\/p>\n<p>C\u00e1c khuy\u1ebfn ngh\u1ecb v\u1ec1 li\u1ec1u l\u01b0\u1ee3ng \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn cho t\u1ea5t c\u1ea3 b\u1ec7nh nh\u00e2n tr\u01b0\u1edfng th\u00e0nh nh\u1eadn \u0111\u01b0\u1ee3c 15 mg ho\u1eb7c 20 mg m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y t\u00f9y thu\u1ed9c v\u00e0o ch\u1ee9c n\u0103ng th\u1eadn.<\/p>\n<p>Thu\u1ed1c \u0111i\u1ec1u ch\u1ebf d\u1ea1ng vi\u00ean n\u00e9n, h\u1ed9p k\u00edn d\u1ec5 b\u1ea3o qu\u1ea3n, v\u1eadn chuy\u1ec3n. Vi\u00ean u\u1ed1ng c\u00f3 th\u1ec3 nghi\u1ec1n, sinh kh\u1ea3 d\u1ee5ng kh\u00f4ng ph\u1ee5 thu\u1ed9c \u0111\u1ed3 \u0103n thu\u1eadn ti\u1ec7n cho nhi\u1ec1u \u0111\u1ed1i t\u01b0\u1ee3ng.<\/p>\n<p>Stellapharm l\u00e0 m\u1ed9t trong nh\u1eefng doanh nghi\u1ec7p l\u1edbn v\u00e0 uy t\u00edn t\u1ea1i Vi\u1ec7t Nam v\u1edbi d\u00e2y chuy\u1ec1n \u0111\u1ea1t chu\u1ea9n GMP.<\/td>\n<td style=\"width: 39.692%\">Thu\u1ed1c c\u00f3 nhi\u1ec1u t\u01b0\u01a1ng t\u00e1c v\u00e0 th\u1eadn tr\u1ecdng li\u00ean quan \u0111\u1ebfn nguy c\u01a1 xu\u1ea5t huy\u1ebft nghi\u00eam tr\u1ecdng<\/p>\n<p>Kh\u00f4ng d\u00f9ng c\u00f9ng NSAIDs\/Thu\u1ed1c ch\u1ed1ng t\u1eadp k\u1ebft ti\u1ec3u c\u1ea7u, c\u00e1c thu\u1ed1c l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u khi d\u00f9ng c\u00f9ng Rivaroxaban.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3 Veronica Ashton v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng 13 th\u00e1ng 3 n\u0103m 2021).<em>The Pharmacology, Efficacy, and Safety of Rivaroxaban in Renally Impaired Patient Populations<\/em>. Truy c\u1eadp ng\u00e0y 21 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33599985\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33599985\/<\/a><\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3o Robyn Konicki v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng 7 th\u00e1ng 5 n\u0103m 2020).<em>Rivaroxaban Precision Dosing Strategy for Real-World Atrial Fibrillation Patients<\/em>. Truy c\u1eadp ng\u00e0y 21 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32267996\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32267996\/<\/a><\/span><\/li>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Xelostad 10 Stella do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i b\u1ea3n PDF <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2023\/11\/Huong-dan-su-dung-thuoc-Xelostad-10-vnras.pdf\">t\u1ea1i \u0111\u00e2y.<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Xelostad 10mg Stella ch\u1ee9a th\u00e0nh ph\u1ea7n Rivaroxaban, l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng huy\u1ebft kh\u1ed1i<\/p>\n","protected":false},"author":490,"featured_media":58365,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-58363","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/58363","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=58363"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/58365"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=58363"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=58363"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=58363"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}