﻿{"id":58240,"date":"2023-11-20T22:36:47","date_gmt":"2023-11-20T15:36:47","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=58240"},"modified":"2025-07-24T13:44:13","modified_gmt":"2025-07-24T06:44:13","slug":"zapnex-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/zapnex-5\/","title":{"rendered":"Zapnex-5"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, D<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b>\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m <a href=\"https:\/\/vnras.com\/drug\/zapnex-5\/\">thu\u1ed1c Zapnex-5<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-27457-17.<\/b><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Zapnex-5 l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\">M\u1ed7i <\/span><b>vi\u00ean n\u00e9n thu\u1ed1c Zapnex-5<\/b><span style=\"font-weight: 400\"> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/td>\n<td><span style=\"font-weight: 400\">H\u00e0m l\u01b0\u1ee3ng<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Olanzapine<\/span><\/td>\n<td><span style=\"font-weight: 400\">5mg<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c<\/span><\/td>\n<td><span style=\"font-weight: 400\">V\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VD-27457-17.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 10 vi\u00ean.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Zapnex-5<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng\u00a0<\/span><\/h3>\n<p><b>Olanzapine<\/b><span style=\"font-weight: 400\"> l\u00e0 thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n kh\u00f4ng \u0111i\u1ec3n h\u00ecnh c\u00f3 \u00e1i l\u1ef1c v\u1edbi c\u00e1c th\u1ee5 th\u1ec3 serotonin 5-HT2A\/2C, dopamine D1-4, histamine H1 v\u00e0 adrenergic \u03b11. Hi\u1ec7u qu\u1ea3 \u0111\u01b0\u1ee3c cho l\u00e0 qua trung gian th\u00f4ng qua s\u1ef1 \u0111\u1ed1i kh\u00e1ng k\u1ebft h\u1ee3p c\u1ee7a c\u00e1c v\u1ecb tr\u00ed th\u1ee5 th\u1ec3 dopamine v\u00e0 serotonin lo\u1ea1i 2.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<ul>\n<li><span style=\"font-weight: 400\">H\u1ea5p thu: H\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Th\u1eddi gian \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 5-8 gi\u1edd sau khi u\u1ed1ng.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1: Ph\u00e2n b\u1ed1 v\u00e0o s\u1eefa m\u1eb9. Li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng: Kho\u1ea3ng 93%.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a: \u1ede gan th\u00f4ng qua qu\u00e1 tr\u00ecnh glucuronid h\u00f3a tr\u1ef1c ti\u1ebfp v\u00e0 oxy h\u00f3a qua trung gian isoenzyme CYP1A2 v\u00e0 \u1edf m\u1ee9c \u0111\u1ed9 th\u1ea5p h\u01a1n l\u00e0 CYP2D6.<\/span><\/li>\n<li><span style=\"font-weight: 400\">B\u00e0i ti\u1ebft: Qua n\u01b0\u1edbc ti\u1ec3u (kho\u1ea3ng 57%) ch\u1ee7 y\u1ebfu d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a v\u00e0 ph\u00e2n (kho\u1ea3ng 30%).<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Zapnex-5 tr\u1ecb b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Zapnex-5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400\">Ng\u01b0\u1eddi b\u1ecb t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t.<\/span><\/li>\n<li><span style=\"font-weight: 400\">\u0110i\u1ec1u tr\u1ecb nh\u1eefng \u0111\u1ee3t h\u01b0ng c\u1ea3m t\u1eeb v\u1eeba \u0111\u1ebfn n\u1eb7ng.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Ng\u1eeba t\u00e1i ph\u00e1t r\u1ed1i lo\u1ea1n l\u01b0\u1ee1ng c\u1ef1c \u1edf b\u1ec7nh nh\u00e2n c\u00f3 giai \u0111o\u1ea1n h\u01b0ng c\u1ea3m \u0111\u00e1p \u1ee9ng v\u1edbi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng olanzapine.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Duy tr\u00ec c\u1ea3i thi\u1ec7n hi\u1ec7u qu\u1ea3 \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e3 c\u00f3 \u0111\u00e1p \u1ee9ng v\u1edbi li\u1ec1u \u0111i\u1ec1u tr\u1ecb kh\u1edfi \u0111\u1ea7u..<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Zapnex-5<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Ng\u01b0\u1eddi l\u1edbn<\/span><\/h3>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400\">M\u1ee5c \u0111\u00edch<\/span><\/td>\n<td><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">\u0110i\u1ec1u tr\u1ecb t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t<\/span><\/td>\n<td><span style=\"font-weight: 400\">Li\u1ec1u kh\u1edfi \u0111\u1ea7u 1-2 vi\u00ean. Ng\u00e0y u\u1ed1ng 1 l\u1ea7n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Li\u1ec1u duy tr\u00ec: 2-4 vi\u00ean, ng\u00e0y u\u1ed1ng 1 l\u1ea7n.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">\u0110i\u1ec1u tr\u1ecb b\u1ec7nh l\u01b0\u1ee1ng c\u1ef1c<\/span><\/td>\n<td><span style=\"font-weight: 400\">\u0110\u01a1n tr\u1ecb li\u1ec7u: 2-3 vi\u00ean\/ng\u00e0y, li\u1ec1u duy tr\u00ec l\u00e0 1 &#8211; 4 vi\u00ean\/ng\u00e0y. Li\u1ec1u t\u1ed1i \u0111a khuy\u1ebfn c\u00e1o l\u00e0 4 vi\u00ean\/ng\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Li\u1ec7u ph\u00e1p ph\u1ed1i h\u1ee3p: Li\u1ec1u kh\u1edfi \u0111\u1ea7u 2-3 vi\u00ean\/ng\u00e0y, u\u1ed1ng 1 l\u1ea7n. Li\u1ec1u d\u00f9ng c\u00f3 th\u1ec3 dao \u0111\u1ed9ng t\u1eeb 1-4 vi\u00ean\/ng\u00e0y.\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Ph\u00f2ng ng\u1eeba t\u00e1i ph\u00e1t r\u1ed1i lo\u1ea1n l\u01b0\u1ee1ng c\u1ef1c<\/span><\/td>\n<td><span style=\"font-weight: 400\">Kho\u1ea3ng li\u1ec1u 1-4 vi\u00ean\/ng\u00e0y.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">Tr\u1ebb em<\/span><\/h3>\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 27.1967%\"><span style=\"font-weight: 400\">\u0110\u1ed1i t\u01b0\u1ee3ng<\/span><\/td>\n<td style=\"width: 71.827%\"><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.1967%\"><span style=\"font-weight: 400\">Tr\u1ebb d\u01b0\u1edbi 13 tu\u1ed5i<\/span><\/td>\n<td style=\"width: 71.827%\"><span style=\"font-weight: 400\">Ch\u01b0a x\u00e1c \u0111i\u0323nh \u0111\u1ed9 an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.1967%\"><span style=\"font-weight: 400\">Tr\u1ebb t\u1eeb 13 &#8211; 17 tu\u1ed5i<\/span><\/td>\n<td style=\"width: 71.827%\"><span style=\"font-weight: 400\">S\u1eed d\u1ee5ng th\u1eadn tr\u1ecdng d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a b\u00e1c s\u0129 chuy\u00ean khoa.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.1967%\"><span style=\"font-weight: 400\">T\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t<\/span><\/td>\n<td style=\"width: 71.827%\"><span style=\"font-weight: 400\">Li\u1ec1u kh\u1edfi \u0111\u1ea7u: n\u1eeda vi\u00ean ho\u1eb7c 1 vi\u00ean\/ng\u00e0y u\u1ed1ng 1 l\u1ea7n. Li\u1ec1u \u0111\u00edch 2 vi\u00ean\/ng\u00e0y. Li\u1ec1u t\u1ed1i \u0111a 4 vi\u00ean\/ng\u00e0y.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.1967%\"><span style=\"font-weight: 400\">B\u1ec7nh l\u01b0\u1ee1ng c\u1ef1c<\/span><\/td>\n<td style=\"width: 71.827%\"><span style=\"font-weight: 400\">Li\u1ec1u kh\u1edfi \u0111\u1ea7u:\u00a0 n\u1eeda vi\u00ean ho\u1eb7c 1 vi\u00ean\/ng\u00e0y u\u1ed1ng 1 l\u1ea7n. Li\u1ec1u \u0111\u00edch 10 mg\/ng\u00e0y. Li\u1ec1u \u0111\u00edch 2 vi\u00ean\/ng\u00e0y. Li\u1ec1u t\u1ed1i \u0111a 4 vi\u00ean\/ng\u00e0y.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">\u0110\u1ed1i t\u01b0\u1ee3ng kh\u00e1c<\/span><\/h3>\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 27.0571%\"><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n suy th\u1eadn ho\u1eb7c suy gan<\/span><\/td>\n<td style=\"width: 71.9666%\"><span style=\"font-weight: 400\">Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u1ea5p 1 vi\u00ean n\u00ean \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y. Trong tr\u01b0\u1eddng h\u1ee3p suy gan trung b\u00ecnh, li\u1ec1u kh\u1edfi \u0111\u1ea7u n\u00ean l\u00e0 1 vi\u00ean v\u00e0 ch\u1ec9 t\u0103ng li\u1ec1u m\u1ed9t c\u00e1ch th\u1eadn tr\u1ecdng.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.0571%\"><span style=\"font-weight: 400\">Ng\u01b0\u1eddi cao tu\u1ed5i<\/span><\/td>\n<td style=\"width: 71.9666%\"><span style=\"font-weight: 400\">Li\u1ec1u kh\u1edfi \u0111\u1ea7u ng\u00e0y 1 vi\u00ean.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.0571%\"><span style=\"font-weight: 400\">Ng\u01b0\u1eddi h\u00fat thu\u1ed1c l\u00e1<\/span><\/td>\n<td style=\"width: 71.9666%\"><span style=\"font-weight: 400\">Kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u. Khuy\u1ebfn c\u00e1o theo d\u00f5i l\u00e2m s\u00e0ng v\u00e0 c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc t\u0103ng li\u1ec1u olanzapine n\u1ebfu c\u1ea7n thi\u1ebft.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.0571%\"><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p ng\u01b0ng d\u00f9ng thu\u1ed1c<\/span><\/td>\n<td style=\"width: 71.9666%\"><span style=\"font-weight: 400\">N\u00ean c\u00e2n nh\u1eafc gi\u1ea3m li\u1ec1u t\u1eeb t\u1eeb khi ng\u1eebng olanzapine.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Zapnex-5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<ul>\n<li><span style=\"font-weight: 400\">Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi olanzapine ho\u1eb7c m\u1ed9t trong c\u00e1c th\u00e0nh ph\u1ea7n kh\u00e1c c\u1ee7a thu\u1ed1c.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 t\u0103ng nh\u00e3n \u00e1p g\u00f3c \u0111\u00f3ng.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Tr\u1ebb em d\u01b0\u1edbi 13 tu\u1ed5i.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Zapnex-5<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<ul>\n<li><span style=\"font-weight: 400\">\u0110\u1ecdc k\u1ef9 h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng tr\u01b0\u1edbc khi d\u00f9ng. D\u00f9ng \u0111\u00fang li\u1ec1u l\u01b0\u1ee3ng \u0111\u00e3 \u0111\u01b0\u1ee3c nh\u00e0 s\u1ea3n xu\u1ea5t khuy\u1ebfn c\u00e1o, kh\u00f4ng t\u1ef1 \u00fd t\u0103ng ho\u1eb7c gi\u1ea3m li\u1ec1u l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Kh\u00f4ng d\u00f9ng cho ng\u01b0\u1eddi b\u1ecb d\u1ecb \u1ee9ng v\u1edbi m\u1ed9t trong c\u00e1c th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c.<\/span><\/li>\n<li><span style=\"font-weight: 400\">Khi s\u1eed d\u1ee5ng thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n tr\u00ean b\u1ec7nh nh\u00e2n, n\u00ean theo d\u00f5i c\u1ea9n th\u1eadn b\u1ec7nh nh\u00e2n trong giai \u0111o\u1ea1n n\u00e0y. M\u1ed9t s\u1ed1 nguy c\u01a1 c\u00f3 th\u1ec3 x\u1ea3y ra \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e3 t\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c nh\u01b0 nh\u01b0 t\u1ef1 t\u1eed, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n, h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf, \u0111\u1ed9t t\u1eed tim, t\u0103ng th\u00e2n nhi\u1ec7t, kh\u00f3 nu\u1ed1t, T\u0103ng prolactin huy\u1ebft.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c Zapnex-5<\/span><\/h3>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400\">T\u1ea7n su\u1ea5t xu\u1ea5t hi\u1ec7n t\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/td>\n<td><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">R\u1ea5t th\u01b0\u1eddng g\u1eb7p<\/span><\/td>\n<td><span style=\"font-weight: 400\">T\u0103ng c\u00e2n, bu\u1ed3n ng\u1ee7, h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf, t\u0103ng n\u1ed3ng \u0111\u1ed9 prolactin huy\u1ebft t\u01b0\u01a1ng.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Th\u01b0\u1eddng g\u1eb7p<\/span><\/td>\n<td><span style=\"font-weight: 400\">T\u0103ng b\u1ea1ch c\u1ea7u \u01b0a acid, gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh.<\/span><\/p>\n<p><span style=\"font-weight: 400\">T\u0103ng n\u1ed3ng \u0111\u1ed9 cholesterol, t\u0103ng n\u1ed3ng \u0111\u1ed9 glucose, t\u0103ng n\u1ed3ng \u0111\u1ed9 triglycerid, glucose ni\u1ec7u, t\u0103ng c\u1ea3m gi\u00e1c ngon mi\u1ec7ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Ch\u00f3ng m\u1eb7t, ch\u1ee9ng ng\u1ed3i n\u1eb1m kh\u00f4ng y\u00ean, Parkinson, r\u1ed1i lo\u1ea1n v\u1eadn \u0111\u1ed9ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">T\u00e1o b\u00f3n v\u00e0 kh\u00f4 mi\u1ec7ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Suy nh\u01b0\u1ee3c, m\u1ec7t m\u1ecfi, ph\u00f9, s\u1ed1t, ph\u00e1t ban.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">\u00cdt g\u1eb7p<\/span><\/td>\n<td><span style=\"font-weight: 400\">Qu\u00e1 m\u1eabn, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng ti\u1ebfn tri\u1ec3n ho\u1eb7c n\u1eb7ng h\u01a1n th\u01b0\u1eddng k\u00e8m nhi\u1ec5m toan ceton ho\u1eb7c h\u00f4n m\u00ea, bao g\u1ed3m m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p t\u1eed vong.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Co gi\u1eadt,\u00a0 r\u1ed1i lo\u1ea1n v\u1eadn \u0111\u1ed9ng mu\u1ed9n, suy gi\u1ea3m tr\u00ed nh\u1edb, lo\u1ea1n v\u1eadn ng\u00f4n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Ch\u1eadm nh\u1ecbp tim, k\u00e9o d\u00e0i kho\u1ea3ng QT.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Huy\u1ebft kh\u1ed1i, ti\u1ec3u kh\u00f4ng t\u1ef1 ch\u1ee7, b\u00ed ti\u1ec3u, kh\u00f4ng ti\u1ec3u \u0111\u01b0\u1ee3c.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">V\u00fa to v\u00f4 kinh, ti\u1ebft nhi\u1ec1u s\u1eefa \u1edf ph\u1ee5 n\u1eef, n\u1eef h\u00f3a tuy\u1ebfn v\u00fa\/ v\u00fa to \u1edf nam gi\u1edbi.\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Hi\u1ebfm g\u1eb7p<\/span><\/td>\n<td><span style=\"font-weight: 400\">Gi\u1ea3m ti\u1ec3u c\u1ea7u, h\u1ea1 th\u00e2n nhi\u1ec7t, Nh\u1ecbp nhanh th\u1ea5t ho\u1eb7c rung th\u1ea5t, \u0111\u1ed9t t\u1eed.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Vi\u00eam t\u1ee5y, vi\u00eam gan, c\u01b0\u01a1ng d\u01b0\u01a1ng k\u00e9o d\u00e0i.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">Thu\u1ed1c<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">Levomethadyl<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">D\u00f9ng ph\u1ed1i h\u1ee3p g\u00e2y t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh tr\u00ean tim (k\u00e9o d\u00e0i kho\u1ea3ng QT, xo\u1eafn \u0111\u1ec9nh, ng\u1eebng tim).<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">Metoclopramid<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">D\u00f9ng \u0111\u1ed3ng th\u1eddi g\u00e2y t\u0103ng nguy c\u01a1 xu\u1ea5t hi\u1ec7n h\u1ed9i ch\u1ee9ng ngo\u1ea1i th\u00e1p, h\u1ed9i ch\u1ee9ng an th\u1ea7n kinh \u00e1c t\u00ednh.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">Thu\u1ed1c \u1ee9c ch\u1ebf h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng nh\u01b0 r\u01b0\u1ee3u, c\u00e1c d\u1eabn ch\u1ea5t benzodiazepin\u00a0<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">L\u00e0m t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf c\u1ee7a olanzapine.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf CYP450 (cafein, cimetidin, erythromycin, ciprofloxacin, quinidin, m\u1ed9t s\u1ed1 thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m nh\u01b0 fluvoxamine)<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">L\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 olanzapine trong m\u00e1u<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">Dopamin, adrenalin ho\u1eb7c c\u00e1c thu\u1ed1c t\u00e1c \u0111\u1ed9ng gi\u1ed1ng giao c\u1ea3m kh\u00e1c tr\u00ean th\u1ee5 th\u1ec3 beta<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi olanzapine c\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam h\u1ea1 huy\u1ebft \u00e1p do t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 alpha c\u1ee7a olanzapine.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">C\u00e1c thu\u1ed1c g\u00e2y c\u1ea3m \u1ee9ng CYP450<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">L\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 olanzapine trong m\u00e1u.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">Thu\u1ed1c kh\u00e1ng cholinergic<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">Olanzapine l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a c\u00e1c thu\u1ed1c b\u00ean.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.7908%\"><span style=\"font-weight: 400\">Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb Parkinson<\/span><\/td>\n<td style=\"width: 49.0934%\"><span style=\"font-weight: 400\">Olanzapin c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a c\u00e1c thu\u1ed1c \u0111\u00f3.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 t\u00ednh an to\u00e0n khi s\u1eed d\u1ee5ng thu\u1ed1c tr\u00ean ph\u1ee5 n\u1eef c\u00f3 thai, n\u00ean h\u1ecfi \u00fd ki\u1ebfn b\u00e1c s\u0129 tr\u01b0\u1edbc khi d\u00f9ng \u0111\u1ec3 c\u00e2n nh\u1eafc gi\u1eefa nguy c\u01a1 v\u00e0 l\u1ee3i \u00edch.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef cho con b\u00fa kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Zapnex-5.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho olanzapin. Tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u, c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng nh\u1eefng bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb qu\u00e1 li\u1ec1u chu\u1ea9n nh\u01b0 r\u1eeda d\u1ea1 d\u00e0y, d\u00f9ng than ho\u1ea1t t\u00ednh.<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Zapnex-5 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Zapnex-5 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Zapnex-5 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Zapnex-5 nh\u01b0:\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/savi-olanzapine\/\"><span style=\"font-weight: 400\">SaVi Olanzapine<\/span><\/a><span style=\"font-weight: 400\"> v\u1edbi th\u00e0nh ph\u1ea7n Olanzapin v\u1edbi h\u00e0m l\u01b0\u1ee3ng 10 mg, c\u00f3 t\u00e1c d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb th\u1ec3 t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t ho\u1eb7c c\u00e1c r\u1ed1i lo\u1ea1n kh\u00e1c v\u1ec1 t\u00e2m th\u1ea7n cho ng\u01b0\u1eddi b\u1ec7nh b\u1ecb k\u00edch \u0111\u1ed9ng, hoang t\u01b0\u1edfng, r\u1ed1i lo\u1ea1n nh\u1eadn th\u1ee9c v\u00e0 suy ngh\u0129, th\u1edd \u01a1, v\u00f4 c\u1ea3m. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m SaVi \u2013 VI\u1ec6T NAM v\u00e0 \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 87,000\u0111.<\/span><\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/morientes-200mg\/\"><span style=\"font-weight: 400\">Morientes 200mg<\/span><\/a><span style=\"font-weight: 400\"> v\u1edbi th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 quetiapine 200mg d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd v\u1ec1 t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t, r\u1ed1i lo\u1ea1n l\u01b0\u1ee1ng c\u1ef1c. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa \u2013 DAVIPHARM v\u00e0 \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng v\u1edbi gi\u00e1 560,000\u0111.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Zapnex-5?<\/span><\/h2>\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 50.9066%\"><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 47.9777%\"><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9066%\"><span style=\"font-weight: 400\">\u0110\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean n\u00e9n, ti\u1ec7n l\u1ee3i khi mang theo s\u1eed d\u1ee5ng.<\/span><\/td>\n<td style=\"width: 47.9777%\"><span style=\"font-weight: 400\">Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 l\u00ean ng\u01b0\u1eddi s\u1eed d\u1ee5ng.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9066%\"><span style=\"font-weight: 400\">\u0110\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa v\u1edbi nh\u00e0 m\u00e1y s\u1ea3n xu\u1ea5t \u0111\u1ea1t chu\u1ea9n GMP, \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng thu\u1ed1c.<\/span><\/td>\n<td style=\"width: 47.9777%\"><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50.9066%\"><span style=\"font-weight: 400\">Gi\u00e1 th\u00e0nh h\u1ee3p l\u00fd.<\/span><\/td>\n<td style=\"width: 47.9777%\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Chuy\u00ean gia MIMS. <\/span><i><span style=\"font-weight: 400\">Olanzapine<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 20 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <\/span><a href=\"https:\/\/www.mims.com\/vietnam\/drug\/info\/olanzapine?mtype=generic\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/www.mims.com\/vietnam\/drug\/info\/olanzapine.<\/span><\/a><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c. T\u1ea3i b\u1ea3n pdf <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2023\/11\/To-HDSD-thuoc-Zapnex-5-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>.<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Zapnex-5 v\u1edbi th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t Olanzapine 5mg, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t, \u0111i\u1ec1u tr\u1ecb c\u00e1c c\u01a1n h\u01b0ng c\u1ea3m m\u1ee9c \u0111\u1ed9 t\u1eeb trung b\u00ecnh t\u1edbi n\u1eb7ng, ng\u1eeba\u00a0t\u00e1i ph\u00e1t tri\u1ec7u ch\u1ee9ng r\u1ed1i lo\u1ea1n l\u01b0\u1ee1ng c\u1ef1c \u1edf b\u1ec7nh nh\u00e2n t\u1eebng b\u1ecb m\u1eafc ch\u1ee9ng h\u01b0ng c\u1ea3m \u0111\u00e3 d\u00f9ng olanzapine.<\/p>\n","protected":false},"author":490,"featured_media":58242,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-58240","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/58240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=58240"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/58242"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=58240"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=58240"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=58240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}