{"id":57848,"date":"2023-11-19T17:22:47","date_gmt":"2023-11-19T10:22:47","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=57848"},"modified":"2025-07-24T13:44:18","modified_gmt":"2025-07-24T06:44:18","slug":"thuoc-tolucombi-80mg-12-5mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-tolucombi-80mg-12-5mg\/","title":{"rendered":"Tolucombi 80mg\/12.5mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/thuoc-tolucombi-80mg-12-5mg\/\">Tolucombi 80mg\/12.5mg<\/a> v\u1edbi th\u00e0nh ph\u1ea7n ch\u1ee9a telmisartan v\u00e0 hydrochlorothiazide, l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p v\u00f4 c\u0103n \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh, do KRKA, D.D., Novo Mesto s\u1ea3n xu\u1ea5t, s\u1ed1 l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-21719-19, \u0111\u0103ng k\u00fd b\u1edfi D\u01b0\u1ee3c ph\u1ea9m Tenamyd.\u00a0<\/b><\/p>\n<h2><span style=\"font-weight: 400\">Tolucombi 80mg\/12.5mg l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\"><strong>Thu\u1ed1c<\/strong> <strong>Tolucombi 80mg\/12.5mg<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\">80 mg telmisartan<\/li>\n<li style=\"font-weight: 400\">12,5 mg hydrochlorothiazide<\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n.\u00a0<\/span><\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VN-21719-19. .<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 4 v\u1ec9 x 7 vi\u00ean.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: KRKA, D.D., Novo Mesto &#8211; Slovenia<\/span><\/p>\n<p>\u0110\u01a1n v\u1ecb \u0111\u0103ng k\u00fd: D\u01b0\u1ee3c ph\u1ea9m Tenamyd<\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Tolucombi 80mg\/12.5mg c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?\u00a0<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng\u00a0<\/span><\/h3>\n<p>Telmisartan c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p. C\u01a1 ch\u1ebf: Telmisartan \u0111\u1ed1i kh\u00e1ng ch\u1ecdn l\u1ecdc v\u1edbi angiotensin II x\u1ea3y ra v\u1edbi \u00e1i l\u1ef1c m\u1ea1nh \u1edf n\u01a1i g\u1eafn v\u1edbi th\u1ee5 th\u1ec3 AT1 t\u1ea1i v\u1ecb tr\u00ed tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn v\u00e0 trong c\u01a1 tr\u01a1n c\u1ee7a m\u1ea1ch m\u00e1u. T\u1eeb \u0111\u00f3 g\u00e2y ra gi\u00e3n m\u1ea1ch v\u00e0 \u1ee9c ch\u1ebf s\u1ea3n xu\u1ea5t aldosteron, d\u1eabn \u0111\u1ebfn gi\u1ea3m l\u01b0\u1ee3ng natri v\u00e0 n\u01b0\u1edbc, \u0111\u1ed3ng th\u1eddi t\u0103ng b\u00e0i ti\u1ebft Kali, d\u1eabn \u0111\u1ebfn gi\u1ea3m huy\u1ebft \u00e1p.<\/p>\n<p>Hydrochlorothiazide c\u00f3 t\u00e1c d\u1ee5ng g\u00e2y h\u1ea1 huy\u1ebft \u00e1p, l\u00e0m gi\u1ea3m ph\u00f9 n\u1ec1 v\u00e0 gi\u1ea3m th\u1ec3 t\u00edch m\u00e1u l\u01b0u th\u00f4ng. C\u01a1 ch\u1ebf: qu\u00e1 tr\u00ecnh t\u00e1i h\u1ea5p thu c\u00e1c Ion Natri v\u00e0 c\u00e1c clorid t\u1ea1i v\u1ecb tr\u00ed \u1ed1ng l\u01b0\u1ee3n xa b\u1ecb \u1ee9c ch\u1ebf b\u1edfi hydrochlorothiazide, t\u1eeb \u0111\u00f3 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng th\u1ea3i tr\u1eeb Natri clorid, magnesi, Kali v\u00e0 l\u00e0m gi\u1ea3m b\u00e0i ti\u1ebft calci. Th\u00f4ng qua \u0111\u00f3, g\u00e2y gi\u1ea3m th\u1ec3 t\u00edch huy\u1ebft t\u01b0\u01a1ng v\u00e0 d\u1ecbch ngo\u1ea1i b\u00e0o, d\u1eabn \u0111\u1ebfn h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 50%;text-align: center\">Telmisartan<\/td>\n<td style=\"width: 50%;text-align: center\">Hydrochlorothiazide<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">H\u1ea5p thu: H\u1ea5p thu nhanh, sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 42%, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t \u0111\u01b0\u1ee3c trong huy\u1ebft t\u01b0\u01a1ng sau 0,5 -1,5 gi\u1edd d\u00f9ng thu\u1ed1c. Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a Telmisartan c\u00f3 th\u1ec3 b\u1ecb \u1ea3nh h\u01b0\u1edfng nh\u1eb9 b\u1edfi \u0111\u1ed3 \u0103n.<\/p>\n<p>Ph\u00e2n b\u1ed1: Li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (&gt;99,5%), ch\u1ee7 y\u1ebfu l\u00e0 li\u00ean k\u1ebft v\u1edbi Albumin v\u00e0 alpha \u2013 1 acid glycoprotein, v\u1edbi th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 trung b\u00ecnh l\u00e0 500l \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Ph\u1ea3n \u1ee9ng li\u00ean h\u1ee3p v\u1edbi glucuronide gi\u00fap chuy\u1ec3n h\u00f3a Telmisartan, c\u00e1c ch\u1ea5t sau chuy\u1ec3n h\u00f3a kh\u00f4ng th\u1ec3 hi\u1ec7n t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ra ph\u00e2n qua \u0111\u01b0\u1eddng m\u1eadt, th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u v\u1edbi l\u01b0\u1ee3ng kho\u1ea3ng 2% li\u1ec1u d\u00f9ng. Th08\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 20 gi\u1edd<\/td>\n<td style=\"width: 50%\">H\u1ea5p thu: H\u1ea5p thu t\u01b0\u01a1ng \u0111\u1ed1i nhanh, sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 60%, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t \u0111\u01b0\u1ee3c trong huy\u1ebft t\u01b0\u01a1ng sau 1 \u2013 3 gi\u1edd s\u1eed d\u1ee5ng.<\/p>\n<p>Ph\u00e2n b\u1ed1: Li\u00ean k\u1ebft v\u1edbi 68% protein huy\u1ebft t\u01b0\u01a1ng, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 0,83 \u2013 1,14 l\/kg.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Kh\u00f4ng b\u1ecb chuy\u1ec3n h\u00f3a trong c\u01a1 th\u1ec3 ng\u01b0\u1eddi.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng chuy\u1ec3n h\u00f3a. Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 10 \u2013 15 gi\u1edd<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Tolucombi 80mg\/12.5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p kh\u00f4ng r\u00f5 nguy\u00ean do \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh.<\/p>\n<p>C\u00f3 th\u1ec3 k\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c t\u0103ng huy\u1ebft \u00e1p kh\u00e1c n\u1ebfu c\u1ea7n thi\u1ebft<\/p>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng &#8211; c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Tolucombi 80mg\/12.5mg<\/span><\/h2>\n<h3>C\u00e1ch d\u00f9ng thu\u1ed1c Tolucombi 80mg\/12.5mg<\/h3>\n<p>S\u1eed d\u1ee5ng 1 vi\u00ean thu\u1ed1c Tolucombi 80mg\/12.5mg m\u1ed7i ng\u00e0y, u\u1ed1ng c\u00f9ng v\u1edbi n\u01b0\u1edbc, tr\u01b0\u1edbc ho\u1eb7c sau b\u1eefa \u0103n.<\/p>\n<p>Khi d\u00f9ng kh\u00f4ng n\u00ean nhai, nghi\u1ec1n ho\u1eb7c b\u1ebb vi\u00ean \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c.<\/p>\n<h3>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Tolucombi 80mg\/12.5mg<\/h3>\n<p>Ng\u01b0\u1eddi l\u1edbn: 1vi\u00ean\/ng\u00e0y.<\/p>\n<p>Thu\u1ed1c kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n b\u1ecb suy gan n\u1eb7ng<\/p>\n<p>B\u1ec7nh nh\u00e2n suy th\u1eadn: li\u1ec1u l\u01b0\u1ee3ng kh\u00f4ng n\u00ean v\u01b0\u1ee3t qu\u00e1 li\u1ec1u 40mg Telmisartan<\/p>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Tolucombi 80mg\/12.5mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p>Nh\u1ea1y c\u1ea3m v\u1edbi c\u00e1c d\u1eabn xu\u1ea5t sulphonamide (hydrochlorothiazide l\u00e0 d\u1eabn xu\u1ea5t c\u1ee7a sulphonamide).<\/p>\n<p>Nh\u1ea1y c\u1ea3m v\u1edbi ho\u1ea1t ch\u1ea5t ch\u00ednh ho\u1eb7c v\u1edbi c\u00e1c t\u00e1 d\u01b0\u1ee3c.<\/p>\n<p>Ba th\u00e1ng gi\u1eefa v\u00e0 ba th\u00e1ng cu\u1ed1i c\u1ee7a thai k\u1ef3.<\/p>\n<p>R\u1ed1i lo\u1ea1n g\u00e2y \u1ee9 m\u1eadt v\u00e0 t\u1eafc ngh\u1ebdn \u0111\u01b0\u1eddng m\u1eadt.<\/p>\n<p>Suy th\u1eadn n\u1eb7ng (\u0111\u1ed9 thanh th\u1ea3i creatinin &lt; 30 ml\/ph\u00fat).<\/p>\n<p>Suy gan n\u1eb7ng.<\/p>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng ho\u1eb7c suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn (GFR &lt; 60ml\/ph\u00fat\/1,73m2).<\/p>\n<p>H\u1ea1 kali huy\u1ebft, t\u0103ng calci huy\u1ebft kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Ph\u1ed1i h\u1ee3p thu\u1ed1c v\u1edbi aliskiren<\/p>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Tolucombi 80mg\/12.5mg<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<p>Trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng thu\u1ed1c Tolucombi 80mg\/12.5mg, c\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi nh\u1eefng tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<p>Suy gan: khuy\u1ebfn c\u00e1o kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng \u0111\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang trong t\u00ecnh tr\u1ea1ng r\u1ed1i lo\u1ea1n \u1ee9 m\u1eadt, b\u1ecb t\u1eafc \u0111\u01b0\u1eddng m\u1eadt ho\u1eb7c \u1edf giai \u0111o\u1ea1n suy gan n\u1eb7ng v\u00ec c\u00e1c telmisartan ph\u1ea7n l\u1edbn \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua \u0111\u01b0\u1eddng m\u1eadt. C\u00f3 th\u1ec3 th\u1ea5y th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a telmisartan qua gan b\u1ecb gi\u1ea3m \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y.<\/p>\n<p>Thai k\u1ef3: B\u1ec7nh nh\u00e2n c\u00f3 k\u1ebf ho\u1ea1ch mang thai n\u00ean chuy\u1ec3n sang c\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p thay th\u1ebf tr\u1eeb phi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft. Khi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n \u0111\u00e3 mang thai, ngay l\u1eadp t\u1ee9c h\u00e3y d\u1eebng \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00e1c ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i kh\u00e1ng v\u1edbi th\u1ee5 th\u1ec3 angiotensin II v\u00e0 n\u00ean c\u00e2n nh\u1eafc s\u1eed d\u1ee5ng m\u1ed9t tr\u1ecb li\u1ec7u thay th\u1ebf kh\u00e1c.<\/p>\n<p>Suy th\u1eadn v\u00e0 gh\u00e9p th\u1eadn: Thu\u1ed1c kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng v\u1edbi b\u1ec7nh nh\u00e2n \u0111ang b\u1ecb suy th\u1eadn n\u1eb7ng (creatinine &lt; 30 ml\/ph\u00fat). Ch\u1ee9ng t\u0103ng nit\u01a1 huy\u1ebft li\u00ean quan \u0111\u1ebfn thu\u1ed1c l\u1ee3i ti\u1ec3u thiazide c\u00f3 th\u1ec3 x\u1ea3y ra tr\u00ean b\u1ec7nh nh\u00e2n suy ch\u1ee9c n\u0103ng th\u1eadn.<\/p>\n<p>T\u0103ng huy\u1ebft \u00e1p do \u0111\u1ed9ng m\u1ea1ch th\u1eadn: C\u00f3 kh\u1ea3 n\u0103ng l\u00e0m t\u0103ng nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng v\u00e0 suy th\u1eadn khi b\u1ec7nh nh\u00e2n c\u00f3 h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn hai b\u00ean ho\u1eb7c h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn \u0111\u1ebfn qu\u1ea3 th\u1eadn duy nh\u1ea5t \u0111ang c\u00f2n ch\u1ee9c n\u0103ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00e1c thu\u1ed1c g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u1ec7 renin- angiotensin-aldosterone.<\/p>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p<\/p>\n<p>M\u1ec7t m\u1ecfi, \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, hoa m\u1eaft.<\/p>\n<p>T\u0103ng Glucose huy\u1ebft, h\u1ea1 kali huy\u1ebft<\/p>\n<p>\u00cdt g\u1eb7p<\/p>\n<p>Lo l\u1eafng, nh\u1ea1y c\u1ea3m.<\/p>\n<p>H\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf.<\/p>\n<p>Lo\u1ea1n nh\u1ecbp tim, tim \u0111\u1eadp nhanh.<\/p>\n<p>Kh\u00f3 th\u1edf, ng\u1ea5t.<\/p>\n<p>Hi\u1ebfm g\u1eb7p<\/p>\n<p>T\u0103ng acid uric huy\u1ebft, t\u0103ng calci huy\u1ebft, h\u1ea1 natri huy\u1ebft.<\/p>\n<p>Ph\u00e1t ban, m\u00e0y \u0111ay.<\/p>\n<p>Vi\u00eam h\u1ecdng, vi\u00eam ph\u1ebf qu\u1ea3n.<\/p>\n<p>R\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c.<\/p>\n<p>R\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7, c\u01a1 th\u1ec3 suy nh\u01b0\u1ee3c.<\/p>\n<p>R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a: ch\u00e1n \u0103n, bu\u1ed3n n\u00f4n, n\u00f4n, t\u00e1o b\u00f3n, \u1ec9a ch\u1ea3y.<\/p>\n<p>L\u01b0u \u00fd: Telmisartan khi d\u00f9ng c\u00f9ng v\u1edbi Hydrochlorothiazide kh\u00f4ng g\u00e2y ra t\u00e1c d\u1ee5ng ph\u1ee5 chung m\u1edbi, c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i x\u1ea3y ra c\u00f3 nguy\u00ean nh\u00e2n t\u1eeb 1 trong 2 ch\u1ea5t, tuy nhi\u00ean \u0111a ph\u1ea7n \u0111\u1ec1u nh\u1eb9 v\u00e0 th\u01b0\u1eddng t\u1ef1 kh\u1ecfi<\/p>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n<p>Vi\u1ec7c k\u1ebft h\u1ee3p Telmisartan v\u00e0 Hydrochlorothiazide kh\u00f4ng l\u00e0m xu\u1ea5t hi\u1ec7n c\u00e1c t\u01b0\u01a1ng t\u00e1c m\u1edbi, t\u01b0\u01a1ng t\u00e1c thu\u1ed1c x\u1ea3y ra l\u00e0 do t\u01b0\u01a1ng t\u00e1c v\u1edbi 1 ho\u1eb7c c\u1ea3 2 th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c.<\/p>\n<table style=\"border-collapse: collapse;width: 100%;height: 42px\">\n<tbody>\n<tr style=\"height: 21px\">\n<td style=\"width: 49.4723%;height: 21px\">T\u01b0\u01a1ng t\u00e1c v\u1edbi Telmisartan<\/td>\n<td style=\"width: 50.5277%;height: 21px\">T\u01b0\u01a1ng t\u00e1c v\u1edbi Hydrochlorothiazide<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 49.4723%;height: 21px\">Aliskiren: Kh\u00f4ng s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi aliskiren v\u1edbi telmisartan \u1edf b\u1ec7nh nh\u00e2n b\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, b\u1ec7nh nh\u00e2n suy th\u1eadn.<\/p>\n<p>Digoxin: Khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi telmisartan, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh v\u00e0 n\u1ed3ng \u0111\u1ed9 \u0111\u00e1y c\u1ee7a Digoxin t\u0103ng t\u01b0\u01a1ng \u1ee9ng 49% v\u00e0 20%. Do v\u1eady, c\u1ea7n theo d\u00f5i n\u1ed3ng \u0111\u1ed9 digoxin khi b\u1eaft \u0111\u1ea7u, \u0111i\u1ec1u ch\u1ec9nh ho\u1eb7c ng\u1eebng s\u1eed dung telmisartan.<\/p>\n<p>Lithi: N\u1ed3ng \u0111\u1ed9 trong huy\u1ebft thanh v\u00e0 \u0111\u1ed9c t\u00ednh c\u1ee7a lithi c\u00f3 th\u1ec3 t\u0103ng l\u00ean khi ph\u1ed1i h\u1ee3p v\u1edbi telmisartan. N\u1ebfu vi\u1ec7c s\u1eed d\u1ee5ng ph\u1ed1i h\u1ee3p l\u00e0 c\u1ea7n thi\u1ebft, n\u00ean theo d\u00f5i c\u1ea9n th\u1eadn n\u1ed3ng \u0111\u1ed9 lithi trong huy\u1ebft thanh.<\/p>\n<p>NSAID: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a telmisartan.<\/p>\n<p>Thu\u1ed1c l\u1ee3i ti\u1ec3u thiazid ho\u1eb7c l\u1ee3i ti\u1ec3u quai: \u0110i\u1ec1u tr\u1ecb tr\u01b0\u1edbc b\u1eb1ng thu\u1ed1c l\u1ee3i ti\u1ec3u li\u1ec1u cao nh\u01b0 furosemid (thu\u1ed1c l\u1ee3i ti\u1ec3u quai) v\u00e0 hydroclorothiazid (thu\u1ed1c l\u1ee3i ti\u1ec3u thiazid) c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn suy gi\u1ea3m th\u1ec3 t\u00edch v\u00e0 c\u00f3 nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng telmisartan.<\/p>\n<p>C\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p kh\u00e1c: T\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a telmisartan c\u00f3 th\u1ec3 t\u0103ng l\u00ean khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi c\u00e1c s\u1ea3n ph\u1ea9m thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p kh\u00e1c.<\/p>\n<p>Corticosteroid to\u00e0n th\u00e2n: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a telmisartan.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/td>\n<td style=\"width: 50.5277%;height: 21px\">R\u01b0\u1ee3u, barbiturat ho\u1eb7c thu\u1ed1c ng\u1ee7 g\u00e2y nghi\u1ec7n: T\u0103ng nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p th\u1ebf \u0111\u1ee9ng.<\/p>\n<p>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng (thu\u1ed1c u\u1ed1ng v\u00e0 Insulin): C\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u thu\u1ed1c \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng do hydroclorothiazid l\u00e0m t\u0103ng glucose huy\u1ebft.<\/p>\n<p>C\u00e1c thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p kh\u00e1c: T\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng ho\u1eb7c t\u0103ng nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p.<\/p>\n<p>Corticosteroid, ACTH, Salbutamol, carbenoxolon, amphotericin B ho\u1eb7c reboxetine: L\u00e0m t\u0103ng m\u1ea5t \u0111i\u1ec7n gi\u1ea3i, \u0111\u1eb7c bi\u1ec7t l\u00e0 gi\u1ea3m kali huy\u1ebft. Amin t\u0103ng huy\u1ebft \u00e1p (th\u00ed d\u1ee5 norepinephrine): C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u00e1p \u1ee9ng v\u1edbi amin t\u0103ng huy\u1ebft \u00e1p. C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng chung.<\/p>\n<p>Thu\u1ed1c gi\u00e3n c\u01a1 kh\u00f4ng kh\u1eed c\u1ef1c (th\u00ed d\u1ee5 tubocurarine): C\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u00e1p \u1ee9ng v\u1edbi thu\u1ed1c gi\u00e3n c\u01a1.<\/p>\n<p>Lithi: Kh\u00f4ng n\u00ean d\u00f9ng c\u00f9ng v\u1edbi thu\u1ed1c l\u1ee3i ti\u1ec3u, v\u00ec gi\u1ea3m thanh th\u1ea3i lithi \u1edf th\u1eadn v\u00e0 t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a ch\u1ea5t n\u00e0y.<\/p>\n<p>Thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u, natri ni\u1ec7u v\u00e0 t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a thiazid \u1edf m\u1ed9t s\u1ed1 ng\u01b0\u1eddi b\u1ec7nh. V\u00ec v\u1eady, n\u1ebfu d\u00f9ng c\u00f9ng, ph\u1ea3i theo d\u00f5i ch\u1eb7t ch\u1ebd \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c l\u1ee3i ti\u1ec3u.<\/p>\n<p>Quinidin: D\u1ec5 g\u00e2y xo\u1eafn \u0111\u1ec9nh, l\u00e0m rung th\u1ea5t g\u00e2y t\u1eed vong.<\/p>\n<p>R\u01b0\u1ee3u, barbiturat ho\u1eb7c thu\u1ed1c ng\u1ee7 g\u00e2y nghi\u1ec7n: T\u0103ng nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p th\u1ebf \u0111\u1ee9ng.<\/p>\n<p>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng (thu\u1ed1c u\u1ed1ng v\u00e0 Insulin): C\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u thu\u1ed1c \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng do hydroclorothiazid l\u00e0m t\u0103ng glucose huy\u1ebft.<\/p>\n<p>C\u00e1c thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p kh\u00e1c: T\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng ho\u1eb7c t\u0103ng nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p.<\/p>\n<p>Corticosteroid, ACTH, Salbutamol, carbenoxolon, amphotericin B ho\u1eb7c reboxetine: L\u00e0m t\u0103ng m\u1ea5t \u0111i\u1ec7n gi\u1ea3i, \u0111\u1eb7c bi\u1ec7t l\u00e0 gi\u1ea3m kali huy\u1ebft.<\/p>\n<p>AMin t\u0103ng huy\u1ebft \u00e1p (th\u00ed d\u1ee5 norepinephrine): C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u00e1p \u1ee9ng v\u1edbi amin t\u0103ng huy\u1ebft \u00e1p. C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng chung.<\/p>\n<p>Thu\u1ed1c gi\u00e3n c\u01a1 kh\u00f4ng kh\u1eed c\u1ef1c (th\u00ed d\u1ee5 tubocurarine): C\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u00e1p \u1ee9ng v\u1edbi thu\u1ed1c gi\u00e3n c\u01a1.<\/p>\n<p>Lithi: Kh\u00f4ng n\u00ean d\u00f9ng c\u00f9ng v\u1edbi thu\u1ed1c l\u1ee3i ti\u1ec3u, v\u00ec gi\u1ea3m thanh th\u1ea3i lithi \u1edf th\u1eadn v\u00e0 t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a ch\u1ea5t n\u00e0y.<\/p>\n<p>Thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u, natri ni\u1ec7u v\u00e0 t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a thiazid \u1edf m\u1ed9t s\u1ed1 ng\u01b0\u1eddi b\u1ec7nh. V\u00ec v\u1eady, n\u1ebfu d\u00f9ng c\u00f9ng, ph\u1ea3i theo d\u00f5i ch\u1eb7t ch\u1ebd \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c l\u1ee3i ti\u1ec3u.<\/p>\n<p>Quinidin: D\u1ec5 g\u00e2y xo\u1eafn \u0111\u1ec9nh, l\u00e0m rung th\u1ea5t g\u00e2y t\u1eed vong.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai: Kh\u00f4ng s\u1eed d\u1ee5ng c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 angiotensin II trong su\u1ed1t th\u1eddi k\u1ef3 mang thai. D\u1ef1a tr\u00ean c\u01a1 ch\u1ebf d\u01b0\u1ee3c l\u00fd c\u1ee7a hydrochlorothiazide trong su\u1ed1t qu\u00fd hai v\u00e0 qu\u00fd ba c\u1ee7a thai k\u00ec c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m truy\u1ec1n m\u00e1u qua thai nhi d\u1eabn \u0111\u1ebfn v\u00e0ng da, r\u1ed1i lo\u1ea1n c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i v\u00e0 gi\u1ea3m ti\u1ec3u c\u1ea7u.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: S\u1eed d\u1ee5ng Tolucombi trong th\u1eddi gian cho con b\u00fa kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o. N\u1ebfu s\u1eed d\u1ee5ng Tolucombi trong th\u1eddi gian cho con b\u00fa th\u00ec n\u00ean h\u1ea1 th\u1ea5p li\u1ec1u \u0111\u1ebfn m\u1ee9c c\u00f3 th\u1ec3.<\/p>\n<h3><span style=\"font-weight: 400\">\u1ea2nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/span><\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y t\u00ecnh tr\u1ea1ng h\u1ea1 huy\u1ebft \u00e1p qu\u00e1 m\u1ee9c; ch\u00f3ng m\u1eb7t, hoa m\u1eaft \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u1ea7m nh\u00ecn v\u00e0 kh\u1ea3 n\u0103ng l\u00e1i xe,lao \u0111\u1ed9ng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh<\/p>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng: Bi\u1ec3u hi\u1ec7n n\u1ed5i b\u1eadt nh\u1ea5t c\u1ee7a qu\u00e1 li\u1ec1u telmisartan l\u00e0 huy\u1ebft \u00e1p th\u1ea5p v\u00e0 nh\u1ecbp tim nhanh; ch\u1eadm nh\u1ecbp tim, ch\u00f3ng m\u1eb7t, n\u00f4n m\u1eeda, t\u0103ng creatinin huy\u1ebft thanh v\u00e0 suy th\u1eadn c\u1ea5p c\u0169ng c\u00f3 th\u1ec3 x\u1ea3y ra.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb: Bi\u1ec7n ph\u00e1p \u0111\u1ec1 xu\u1ea5t bao g\u1ed3m g\u00e2y n\u00f4n v\u1eeba r\u1eeda d\u1ea1 d\u00e0y. Than ho\u1ea1t c\u00f3 th\u1ec3 h\u1eefu \u00edch trong \u0111i\u1ec1u tr\u1ecb qu\u00e1 li\u1ec1u, n\u00ean theo d\u00f5i ch\u1ea5t \u0111i\u1ec7n gi\u1ea3i v\u00e0 creatinin th\u01b0\u1eddng xuy\u00ean.<\/p>\n<p>B\u1ec7nh nh\u00e2n n\u00ean \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd, \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 t\u00f9y thu\u1ed9c v\u00e0o th\u1eddi gian k\u1ec3 t\u1eeb l\u00fac h\u1ea5p thu thu\u1ed1c v\u00e0 \u0111\u1ed9 n\u1eb7ng c\u1ee7a tri\u1ec7u ch\u1ee9ng. C\u00e1c ch\u1ea5t \u0111i\u1ec7n gi\u1ea3i v\u00e0 creatinin huy\u1ebft thanh c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i th\u01b0\u1eddng xuy\u00ean. N\u1ebfu huy\u1ebft \u00e1p th\u1ea5p x\u1ea3y ra, b\u1ec7nh nh\u00e2n n\u00ean \u0111\u01b0\u1ee3c \u0111\u1eb7t \u1edf t\u01b0 th\u1ebf n\u1eb1m, nhanh ch\u00f3ng b\u00f9 th\u1ec3 t\u00edch v\u00e0 mu\u1ed1i.<\/p>\n<h3><span style=\"font-weight: 400\">B\u1ea3o qu\u1ea3n<\/span><\/h3>\n<p>B\u1ea3o qu\u1ea3n d\u01b0\u1edbi 30\u00b0C.<\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Tolucombi 80mg\/12.5mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Tolucombi 80mg\/12.5mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Tolucombi 80mg\/12.5mg <\/strong>c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) h\u1ea1 \u00e1p d\u1ea1ng ph\u1ed1i h\u1ee3p kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c nh\u01b0:\u00a0<\/span><\/p>\n<ol>\n<li><a href=\"https:\/\/vnras.com\/drug\/mibetel\/\">Thu\u1ed1c Mibetel Plus<\/a>\u00a0\u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH li\u00ean doanh Hasan-Dermapharm \u2013 VI\u1ec6T NAM, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-32412-19, \u0111\u01b0\u1ee3c \u0111\u0103ng k\u00fd b\u1edfi c\u00f4ng ty TNHH li\u00ean doanh Hasan-Dermapharm Thu\u1ed1c c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Telmisartan v\u1edbi h\u00e0m l\u01b0\u1ee3ng 40mg v\u00e0 hydrochlorothiazide 12.5mg, h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean c\u00f3 gi\u00e1 140.000.<\/li>\n<li><a href=\"https:\/\/vnras.com\/drug\/ocedio-80-125\/\">Thu\u1ed1c Ocedio 80\/12,5<\/a> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Valsartan 80mg v\u00e0 Hydrochlorothiazid 12,5mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00f4ng ty c\u1ed5 ph\u1ea7n H\u00f3a d\u01b0\u1ee3c Vi\u1ec7t Nam v\u00e0 c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd t\u1ea1i l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-29339-18. Thu\u1ed1c s\u1ebd \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi \u0111\u01a1n tr\u1ecb li\u1ec7u. H\u1ed9p 5 v\u1ec9 x 10 vi\u00ean hi\u1ec7n c\u00f3 gi\u00e1 250,000.<\/li>\n<\/ol>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Tolucombi 80mg\/12.5mg?<\/span><\/h2>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 54.2394%;text-align: center\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 45.7606%;text-align: center\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 54.2394%\">Thu\u1ed1c Tolucombi 80mg\/12.5mg l\u00e0 s\u1ef1 k\u1ebft h\u1ee3p h\u00e0i h\u00f2a gi\u1eefa hai ho\u1ea1t ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p, do \u0111\u00f3 kh\u1ea3 n\u0103ng \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n r\u1ea5t t\u1ed1t.<\/p>\n<p>C\u00e1c th\u1eed nghi\u1ec7m \u0111\u00e3 ch\u1ee9ng minh, vi\u1ec7c k\u1ebft h\u1ee3p telmisartan v\u1edbi hydrochlorothiazide gi\u00fap t\u0103ng c\u01b0\u1eddng hi\u1ec7u qu\u1ea3 h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a telmisartan \u1edf g\u1ea7n 2\/3 s\u1ed1 b\u1ec7nh nh\u00e2n t\u0103ng huy\u1ebft \u00e1p c\u00f3 t\u0103ng huy\u1ebft \u00e1p nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh<\/p>\n<p>Thu\u1ed1c Tolucombi c\u00f3 ngu\u1ed3n g\u1ed1c t\u1ea1i Slovenia, hi\u1ec7n \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi h\u1ec7 th\u1ed1ng d\u00e2y chuy\u1ec1n ti\u00ean ti\u1ebfn ch\u1ea5t l\u01b0\u1ee3ng cao v\u00e0 hi\u1ec7n \u0111\u1ea1i b\u1edfi KRKA, D.D. NOVO MESTO.<\/p>\n<p>Li\u1ec1u cao telmisartan\/hydrochlorothiazide cho th\u1ea5y v\u1eabn c\u00f3 kh\u1ea3 n\u0103ng dung n\u1ea1p t\u1ed1t v\u00e0 \u0111\u1ed9 an to\u00e0n cao, c\u1ea3 tr\u00ean ng\u01b0\u1eddi tr\u1ebb tu\u1ed5i v\u00e0 ng\u01b0\u1eddi gi\u00e0 (&gt; 65 tu\u1ed5i)<\/p>\n<p>D\u1ea1ng vi\u00ean n\u00e9n d\u1ec5 b\u1ea3o qu\u1ea3n, thu\u1eadn l\u1ee3i cho s\u1eed d\u1ee5ng v\u00e0 mang \u0111i.<br \/>\nDuy tr\u00ec huy\u1ebft \u00e1p \u1ed5n \u0111\u1ecbnh v\u1edbi 1 vi\u00ean cho c\u1ea3 ng\u00e0y<\/td>\n<td style=\"width: 45.7606%\">\u0110I\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p v\u1edbi Telmisartan\/hydrochlorothiazide th\u01b0\u1eddng \u0111i k\u00e8m theo suy gi\u1ea3m chuy\u1ec3n h\u00f3a Acid Uric v\u00e0 chuy\u1ec3n h\u00f3a glucose<\/p>\n<p>C\u00f3 th\u1ec3 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3 Marc Maillard v\u00e0 Michel Burnier (Ng\u00e0y \u0111\u0103ng:Ng\u00e0y Th\u00e1ng 5 n\u0103m 2005). <em>Telmisartan\/hydrochlorothiazide: a new fixed dose combination<\/em>. Truy c\u1eadp ng\u00e0y 19 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15889965\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/15889965\/<\/a><\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3 Sverre E Kjeldsen v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng: Th\u00e1ng 7 n\u0103m 2013). <em>Telmisartan\/Hydrochlorothiazide combination therapy for the treatment of hypertension: a pooled analysis in older and younger patients<\/em>. Truy c\u1eadp ng\u00e0y 19 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23730986\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/23730986\/<\/a><\/span><\/li>\n<li><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3 Toshihiro Hamada v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng: N\u0103m 2014). <em>A comparative study on the effectiveness of losartan\/hydrochlorothiazide and telmisartan\/hydrochlorothiazide in patients with hypertensio <\/em>Truy c\u1eadp ng\u00e0y 19 th\u00e1ng 11 n\u0103m 2023 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23865441\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/23865441\/<\/a><\/span><\/li>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Tolucombi 80mg\/12.5mg do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i b\u1ea3n PDF <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2023\/11\/Huong-dan-su-dung-thuoc-tolucombi-80-12-5-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Tolucombi 80mg\/12.5mg ch\u1ee9a 80 mg telmisartan v\u00e0 12,5 mg hydrochlorothiazide, h\u1ed9p 4 v\u1ec9 x 10 vi\u00ean n\u00e9n bao phim<\/p>\n","protected":false},"author":490,"featured_media":57849,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-57848","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/57848","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=57848"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/57849"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=57848"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=57848"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=57848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}