{"id":56191,"date":"2023-11-10T10:06:52","date_gmt":"2023-11-10T03:06:52","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=56191"},"modified":"2025-07-24T13:59:41","modified_gmt":"2025-07-24T06:59:41","slug":"acnotin-20","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/acnotin-20\/","title":{"rendered":"Acnotin 20"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/acnotin-20\/\">Acnotin 20<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Mega Lifesciences., Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18371-14<\/strong><\/p>\n<h2>Acnotin 20 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean <strong>Acnotin 20<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: <strong>Isotretinoin 20mg<\/strong><\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang m\u1ec1m.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-18371-14.<br \/>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<br \/>\nXu\u1ea5t x\u1ee9: Th\u00e1i Lan.<\/p>\n<h2>Acnotin 20 c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Theo m\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u cho r\u1eb1ng Isotretinoin t\u00e1c \u0111\u1ed9ng v\u00e0o tuy\u1ebfn b\u00e3 nh\u1eddn, l\u00e0m gi\u1ea3m k\u00edch th\u01b0\u1edbc tuy\u1ebfn b\u00e3 v\u00e0 \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a tuy\u1ebfn n\u00e0y, cu\u1ed1i c\u00f9ng l\u00e0m gi\u1ea3m s\u1ef1 b\u00e0i ti\u1ebft b\u00e3 nh\u1eddn. Ngo\u00e0i ra, Isotretinoin th\u1ec3 hi\u1ec7n t\u00e1c d\u1ee5ng kh\u00e1ng vi\u00eam.<\/p>\n<h3>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu<\/li>\n<\/ul>\n<p>Isotretinoin h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, c\u00f3 \u0111\u1eb7c t\u00ednh \u01b0a lipid cao n\u00ean u\u1ed1ng thu\u1ed1c trong b\u1eefa \u0103n l\u00e0m t\u0103ng sinh kh\u1ea3 d\u1ee5ng.<\/p>\n<ul>\n<li>Ph\u00e2n b\u1ed1<\/li>\n<\/ul>\n<p>Isotretinoin c\u00f3 kh\u1ea3 n\u0103ng li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng chi\u1ebfm \u0111\u1ebfn 99.9%, ch\u1ee7 y\u1ebfu li\u00ean k\u1ebft v\u1edbi albumin.<\/p>\n<p>Ch\u01b0a c\u00f3 nhi\u1ec1u c\u00e1c th\u00f4ng tin v\u1ec1 s\u1ef1 ph\u00e2n b\u1ed1 c\u1ee7a Isotretinoin v\u00e0o c\u00e1c m\u00f4.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong bi\u1ec3u b\u00ec b\u1eb1ng \u00bd trong huy\u1ebft thanh. Isotretinoin th\u00e2m nh\u1eadp k\u00e9m v\u00e0o c\u00e1c t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u, N\u1ed3ng \u0111\u1ed9 Isotretinoin trong huy\u1ebft t\u01b0\u01a1ng g\u1ea5p 1.7 l\u1ea7n n\u1ed3ng \u0111\u1ed9 trong m\u00e1u to\u00e0n ph\u1ea7n.<\/p>\n<ul>\n<li>Chuy\u1ec3n h\u00f3a<\/li>\n<\/ul>\n<p>Isotretinoin chuy\u1ec3n h\u00f3a \u1edf gan v\u00e0 \u1edf c\u1ea3 th\u00e0nh ru\u1ed9t non. 4-oxo-isotretinoin l\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong m\u00e1u v\u00e0 n\u01b0\u1edbc ti\u1ec3u, ngo\u00e0i ra c\u00f2n c\u00f3 ch\u1ea5t chuy\u1ec3n h\u00f3a 4-oxo-tretinoin v\u00e0 tretinoin.<\/p>\n<ul>\n<li>Th\u1ea3i tr\u1eeb<\/li>\n<\/ul>\n<p>Isotretinoin b\u00e0i ti\u1ebft qua m\u1eadt, \u0111\u00e0o th\u1ea3i qua ph\u00e2n v\u00e0 n\u01b0\u1edbc ti\u1ec3u g\u1ea7n nh\u01b0 nhau. Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng t\u1eeb 10 &#8211; 20 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Acnotin 20 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Isotretinoin d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c tr\u01b0\u1eddng h\u1ee3p m\u1ee5n tr\u1ee9ng c\u00e1 n\u1eb7ng m\u00e0 d\u00f9ng c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb th\u00f4ng th\u01b0\u1eddng kh\u00f4ng hi\u1ec7u qu\u1ea3, m\u1ee5n tr\u1ee9ng c\u00e1 k\u00e9o d\u00e0i l\u00e2u n\u0103m \u0111\u1ec3 l\u1ea1i nhi\u1ec1u s\u1eb9o x\u1ea5u, \u1ea3nh h\u01b0\u1edfng l\u1edbn \u0111\u1ebfn ngh\u1ec1 nghi\u1ec7p v\u00e0 t\u00e2m l\u00fd x\u00e3 h\u1ed9i.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Acnotin 20<\/h2>\n<p>\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi l\u1edbn v\u00e0 thanh thi\u1ebfu ni\u00ean d\u00f9ng li\u1ec1u th\u00f4ng th\u01b0\u1eddng l\u00e0 0,5-1mg\/kg\/ ng\u00e0y (chia hai l\u1ea7n, d\u00f9ng trong b\u1eefa \u0103n), th\u1eddi gian \u0111i\u1ec1u tr\u1ecb 15 &#8211; 20 tu\u1ea7n.<\/p>\n<p>B\u1ec7nh nh\u00e2n b\u1ecb m\u1ee5n n\u1eb7ng, m\u1ee5n xu\u1ea5t hi\u1ec7n ngay \u1edf ng\u1ef1c, l\u01b0ng d\u00f9ng li\u1ec1u t\u1ed1i \u0111a l\u00e0 2mg\/kg\/ng\u00e0y.<br \/>\nSau 4 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb, hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c c\u00f3 th\u1ec3 kh\u00e1c nhau \u1edf t\u1eebng b\u1ec7nh nh\u00e2n, v\u00ec v\u1eady t\u00f9y t\u1eebng tr\u01b0\u1eddng h\u1ee3p c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u0111i\u1ec1u tr\u1ecb duy tr\u00ec t\u1eeb 0,1 &#8211; 1mg\/kg\/ng\u00e0y.<\/p>\n<p>Trong th\u1eddi gian \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb m\u1ee5n c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n nhi\u1ec1u h\u01a1n, c\u00f3 th\u1ec3 c\u1ea7n k\u1ebft h\u1ee3p v\u1edbi adrenocorticoid.<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb kho\u1ea3ng 16 tu\u1ea7n. Khi ng\u01b0ng d\u00f9ng thu\u1ed1c ph\u1ea3i \u0111\u1ea3m b\u1ea3o t\u00ecnh tr\u1ea1ng b\u1ec7nh v\u1eabn \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n. Do \u0111\u00f3, tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb nh\u1eafc l\u1ea1i n\u00ean ng\u01b0ng \u00edt nh\u1ea5t 8 tu\u1ea7n v\u00e0 li\u1ec1u nh\u1eafc l\u1ea1i gi\u1ed1ng nh\u01b0 li\u1ec1u ban \u0111\u1ea7u.<\/p>\n<p>Kh\u00f4ng d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u1ea1i ch\u1ed7 m\u1ee5n tr\u1ee9ng c\u00e1 c\u00f3 t\u00e1c d\u1ee5ng ti\u00eau s\u1eebng, l\u00e0m bong da ho\u1eb7c x\u1ea1 tr\u1ecb b\u1eb1ng tia c\u1ef1c t\u00edm. Tr\u00e1nh ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp v\u1edbi \u00e1nh s\u00e1ng m\u1eb7t tr\u1eddi. C\u00f3 th\u1ec3 d\u00f9ng thu\u1ed1c tr\u1ecb m\u1ee5n tr\u1ee9ng c\u00e1 b\u00f4i t\u1ea1i ch\u1ed7 t\u00e1c d\u1ee5ng nh\u1eb9 \u0111\u1ec3 h\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Tr\u1ebb em &lt; 12 tu\u1ed5i kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng s\u1ea3n ph\u1ea9m n\u00e0y.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Acnotin 20 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>B\u1ec7nh nh\u00e2n ng\u1ed9 \u0111\u1ed9c Vitamin A, suy gan, suy th\u1eadn, t\u0103ng lipid m\u00e1u.<\/li>\n<li>M\u1eabn c\u1ea3m v\u1edbi Isotretinoin ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>D\u00f9ng c\u00f9ng v\u1edbi kh\u00e1ng sinh tetracyclin.<\/li>\n<li>Ph\u1ee5 n\u1eef \u0111ang trong giai \u0111o\u1ea1n mang thai\/\u0111\u1ecbnh mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa.<\/li>\n<li>Kh\u00f4ng truy\u1ec1n m\u00e1u c\u1ee7a b\u1ec7nh nh\u00e2n \u0111ang s\u1eed d\u1ee5ng\/s\u1eed d\u1ee5ng Isotretinoin 1 th\u00e1ng tr\u01b0\u1edbc truy\u1ec1n cho ph\u1ee5 n\u1eef c\u00f3 d\u1ef1 \u0111\u1ecbnh mang thai.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Acnotin 20<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Isotretinoin ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng theo ch\u1ec9 \u0111\u1ecbnh c\u1ee7a ng\u01b0\u1eddi c\u00f3 kinh nghi\u1ec7m.<\/li>\n<li>D\u00f9ng Isotretinoin cho ph\u1ee5 n\u1eef mang thai nguy c\u01a1 sinh qu\u00e1i thai.<\/li>\n<li>Ki\u1ec3m tra ch\u1ee9c n\u0103ng gan, n\u1ed3ng \u0111\u1ed9 lipid huy\u1ebft thanh v\u00e0o c\u00e1c th\u1eddi \u0111i\u1ec3m sau: tr\u01b0\u1edbc \u0111i\u1ec1u tr\u1ecb, sau khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb 1 th\u00e1ng v\u00e0 \u0111\u1ecbnh k\u1ef3 sau m\u1ed7i 3 th\u00e1ng.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1eb1ng isotretinoin \u0111\u00e3 c\u00f3 tr\u01b0\u1eddng h\u1ee3p lo\u1ea1n th\u1ea7n, tr\u1ea7m c\u1ea3m v\u00e0 \u00fd \u0111\u1ecbnh t\u1eed t\u1ef1. Th\u1eadn tr\u1ecdng theo d\u00f5i khi \u0111i\u1ec1u tr\u1ecb \u1edf b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed b\u1ec7nh tr\u1ea7m c\u1ea3m.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 th\u1ecb l\u1ef1c v\u00e0 c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/li>\n<li>Ch\u1ec9 d\u00f9ng isotretinoin trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p m\u1ee5n tr\u1ee9ng c\u00e1 n\u1eb7ng, \u0111\u00e1nh gi\u00e1 l\u1ee3i \u00edch\/nguy c\u01a1 khi s\u1eed d\u1ee5ng.<\/li>\n<li>Kh\u00f4ng n\u00ean k\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c tr\u00e1nh thai c\u00f3 ch\u1ee9a androgen progesterol, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 n\u1ed9i ti\u1ebft.<\/li>\n<li>L\u1ed9t da m\u1eb7t trong th\u1eddi gian d\u00f9ng isotretinoin v\u00e0 sau khi ng\u01b0ng thu\u1ed1c 5 &#8211; 6 th\u00e1ng c\u00f3 th\u1ec3 g\u00e2y s\u1eb9o l\u1ed3i.<\/li>\n<li>D\u00f9ng s\u00e1p nh\u1ed5 l\u00f4ng trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb v\u00e0 sau khi ng\u01b0ng thu\u1ed1c 5-6 th\u00e1ng c\u00f3 th\u1ec3 g\u00e2y vi\u00eam da.<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao ( b\u00e9o ph\u00ec, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, nghi\u1ec7n r\u01b0\u1ee3u ho\u1eb7c r\u1ed1i lo\u1ea1n chuy\u1ec3n ho\u00e1 lipid) s\u1eed d\u1ee5ng isotretinoin c\u1ea7n th\u01b0\u1eddng xuy\u00ean ki\u1ec3m tra b\u1eb1ng c\u00e1c x\u00e9t nghi\u1ec7m c\u1eadn l\u00e2m s\u00e0ng.<\/li>\n<li>B\u1ec7nh nh\u00e2n b\u1ecb ho\u1eb7c nghi ng\u1edd b\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng khi d\u00f9ng thu\u1ed1c ph\u1ea3i th\u01b0\u1eddng xuy\u00ean ki\u1ec3m tra glucose huy\u1ebft.<\/li>\n<li>Kh\u00f4 mi\u1ec7ng c\u00f3 th\u1ec3 g\u00e2y ra s\u00e2u r\u0103ng, nhi\u1ec5m n\u1ea5m v\u00e0 b\u1ec7nh v\u1ec1 n\u01b0\u1edbu. C\u00f3 th\u1ec3 ng\u1eadm k\u1eb9o kh\u00f4ng \u0111\u01b0\u1eddng, d\u00f9ng dung d\u1ecbch thay th\u1ebf n\u01b0\u1edbc b\u1ecdt ho\u1eb7c n\u01b0\u1edbc \u0111\u00e1 \u0111\u1ec3 h\u1ea1n ch\u1ebf t\u00ecnh tr\u1ea1ng n\u00e0y.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>C\u00f3 th\u1ec3 g\u1eb7p c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 sau trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb:<\/li>\n<li>Tri\u1ec7u ch\u1ee9ng th\u1eeba vitamin A: kh\u00f4 da v\u00e0 ni\u00eam m\u1ea1c, ch\u1ea3y m\u00e1u cam,n\u1ee9t m\u00f4i, \u0111\u1ee5c gi\u00e1c m\u1ea1c c\u00f3 h\u1ed3i ph\u1ee5c, vi\u00eam k\u1ebft m\u1ea1c m\u1eaft.<\/li>\n<li>Da v\u00e0 c\u00e1c v\u1ecb tr\u00ed kh\u00e1c: ng\u1ee9a, vi\u00eam da, ngo\u1ea1i ban, vi\u00eam quanh m\u00f3ng, r\u1ee5ng t\u00f3c, teo m\u00f3ng, \u0111\u1ed5 m\u1ed3 h\u00f4i u h\u1ea1t m\u01b0ng m\u1ee7, t\u0103ng t\u1ea1o m\u00f4 h\u1ea1t, xu\u1ea5t hi\u1ec7n nhi\u1ec1u tr\u1ee9ng c\u00e1, t\u0103ng s\u1eafc t\u1ed1, r\u1eadm l\u00f4ng, da nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng.<\/li>\n<li>C\u01a1 x\u01b0\u01a1ng: \u0111au c\u01a1, t\u0103ng sinh x\u01b0\u01a1ng, \u0111au kh\u1edbp, vi\u00eam g\u00e2n.<\/li>\n<li>T\u00e2m th\u1ea7n v\u00e0 h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng: tr\u1ea7m c\u1ea3m, r\u1ed1i lo\u1ea1n h\u00e0nh vi, t\u0103ng \u00e1p l\u1ef1c n\u1ed9i s\u1ecd, \u0111au \u0111\u1ea7u, \u0111\u1ed9ng kinh.<\/li>\n<li>Gi\u00e1c quan: r\u1ed1i lo\u1ea1n th\u1ecb tr\u01b0\u1eddng, \u0111\u1ee5c thu\u1ef7 tinh th\u1ec3, s\u1ee3 \u00e1nh s\u00e1ng, gi\u1ea3m th\u00ednh l\u1ef1c, gi\u1ea3m th\u1ecb tr\u01b0\u1eddng v\u1ec1 \u0111\u00eam, vi\u00eam gi\u00e1c m\u1ea1c.<\/li>\n<li>H\u1ec7 ti\u00eau ho\u00e1: bu\u1ed3n n\u00f4n, vi\u00eam h\u1ed3i tr\u00e0ng v\u00e0 k\u1ebft tr\u00e0ng, vi\u00eam \u0111\u1ea1i tr\u00e0ng, ch\u1ea3y m\u00e1u ti\u00eau ho\u00e1.<\/li>\n<li>Gan, m\u1eadt; t\u0103ng men gan c\u00f3 h\u1ed3i ph\u1ee5c, vi\u00eam gan.<\/li>\n<li>H\u00f4 h\u1ea5p: co th\u1eaft ph\u1ebf qu\u1ea3n.<\/li>\n<li>M\u00e1u: t\u0103ng\/gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u, h\u1ed3ng c\u1ea7u, t\u0103ng t\u1ed1c \u0111\u1ed9 l\u1eafng m\u00e1u.<\/li>\n<li>X\u00e9t nghi\u1ec7m c\u1eadn l\u00e2m s\u00e0ng: t\u0103ng acid uric huy\u1ebft, t\u0103ng cholesterol v\u00e0 triglycerid huy\u1ebft thanh, gi\u1ea3m HDL.<\/li>\n<li>Gi\u1ea3m s\u1ee9c \u0111\u1ec1 kh\u00e1ng: nhi\u1ec5m tr\u00f9ng.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi vitamin A c\u00f3 th\u1ec3 g\u00e2y tri\u1ec7u ch\u1ee9ng th\u1eeba vitamin A.<\/p>\n<p>D\u00f9ng ph\u1ed1i h\u1ee3p isotretinoin v\u00e0 tetracylin \u0111\u00e3 c\u00f3 tr\u01b0\u1eddng h\u1ee3p t\u0103ng \u00e1p l\u1ef1c n\u1ed9i s\u1ecd.<\/p>\n<p>T\u00e1c d\u1ee5ng c\u1ee7a progesteron li\u1ec1u th\u1ea5p khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi isotretinoin c\u00f3 th\u1ec3 b\u1ecb gi\u1ea3m. Do \u0111\u00f3, kh\u00f4ng n\u00ean d\u00f9ng progesteron li\u1ec1u th\u1ea5p n\u1ebfu \u0111ang s\u1eed d\u1ee5ng isotretinoin.<\/p>\n<p>Phenytoin c\u00f3 th\u1ec3 gi\u1ea3m t\u00e1c d\u1ee5ng thu\u1ed1c isotretinoin.<\/p>\n<p>Ketoconazol: d\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m th\u1ea3i tr\u1eeb c\u1ee7a c\u1ea3 hai thu\u1ed1c, c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u d\u00f9ng corticosteroid.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai<\/li>\n<\/ul>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c cho ph\u1ee5 n\u1eef mang thai ho\u1eb7c c\u00f3 \u00fd \u0111\u1ecbnh mang thai v\u00ec nguy c\u01a1 g\u00e2y qu\u00e1i thai.<\/p>\n<ul>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa<\/li>\n<\/ul>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c v\u00ec nguy c\u01a1 g\u00e2y h\u1ea1i cho tr\u1ebb.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Tri\u1ec7u ch\u1ee9ng: bu\u1ed3n n\u00f4n, n\u00f4n m\u1eeda, \u0111au b\u1ee5ng, t\u0103ng \u00e1p l\u1ef1c n\u1ed9i s\u1ecd, ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, k\u00edch \u1ee9ng da v\u00e0 ng\u1ee9a.<\/li>\n<li>X\u1eed tr\u00ed: Ng\u1eebng d\u00f9ng thu\u1ed1c, r\u1eeda d\u1ea1 d\u00e0y. Theo d\u00f5i \u00e1p l\u1ef1c n\u1ed9i s\u1ecd, c\u1ea9n tr\u1ecdng v\u1edbi tr\u01b0\u1eddng h\u1ee3p c\u00f3 thai, x\u00e1c \u0111\u1ecbnh n\u1ed3ng \u0111\u1ed9 thu\u1ed1c b\u1eb1ng th\u1eed m\u00e1u.<\/li>\n<\/ul>\n<h3>T\u00e1c \u0111\u1ed9ng tr\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean th\u1ecb gi\u00e1c: hoa m\u1eaft, bu\u1ed3n ng\u1ee7 c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ho\u1ea1t \u0111\u1ed9ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h2>Thu\u1ed1c Acnotin 20 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Acnotin 20<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/novolinda\/\">Novolinda<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m CPC1 H\u00e0 N\u1ed9i, ch\u1ee9a Clindamycin 10mg, Metronidazol 8mg. Thu\u1ed1c d\u00f9ng \u0111i\u1ec1u tr\u1ecb b\u1ec7nh tr\u1ee9ng c\u00e1 \u0111\u1eb7c bi\u1ec7t \u0111\u1ed1i v\u1edbi tr\u1ee9ng c\u00e1 m\u1ee7 v\u00e0 tr\u1ee9ng c\u00e1 b\u1ecdc, b\u1ec7nh tr\u1ee9ng c\u00e1 \u0111\u1ecf, vi\u00eam nang l\u00f4ng v\u00e0 c\u00e1c nhi\u1ec5m khu\u1ea9n da kh\u00e1c. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng dung d\u1ecbch b\u00f4i ngo\u00e0i. B\u1ea1n c\u00f3 th\u1ec3 d\u00f9ng b\u00f4i 3 l\u1ea7n\/ng\u00e0y. Thu\u1ed1c c\u00f3 gi\u00e1 120.000 \u0111\u1ed3ng\/ H\u1ed9p 1 l\u1ecd 30ml.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/kem-acnes\/\">Kem Acnes<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi t\u1eadp \u0111o\u00e0n Rohto \u2013 Vi\u1ec7t Nam ch\u1ee9a Sulfur, Tocopheryl Acetate, Glycyrrhetinic Acid, Resorcin,\u2026 \u0111\u01b0\u1ee3c d\u00f9ng v\u1edbi m\u1ee5c \u0111\u00edch kh\u00e1ng khu\u1ea9n, ch\u1ed1ng vi\u00eam, l\u00e0m kh\u00f4 nh\u00e2n m\u1ee5n, \u0111i\u1ec1u tr\u1ecb c\u00e1c lo\u1ea1i m\u1ee5n tr\u1ee9ng c\u00e1, m\u1ee5n s\u01b0ng vi\u00eam, gi\u00fap gi\u1ea3m h\u00ecnh th\u00e0nh s\u1eb9o m\u1ee5n ho\u1eb7c c\u00e1c v\u1ebft th\u00e2m m\u1ee5n. Thu\u1ed1c c\u00f3 d\u1ea1ng gel b\u00f4i ngo\u00e0i da v\u00e0 c\u00f3 gi\u00e1 44.000 \u0111\u1ed3ng\/ h\u1ed9p 1 tu\u00fdp 22g gel.<\/p>\n<h2>T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Acnotin 20?<\/h2>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 50%;text-align: center\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 50%;text-align: center\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">V\u00e0o n\u0103m 1982, Isotretinoin \u0111\u00e3 \u0111\u01b0\u1ee3c FDA ph\u00ea duy\u1ec7t \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ee5n tr\u1ee9ng c\u00e1 n\u1eb7ng, kh\u00e1ng thu\u1ed1c, kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi li\u1ec7u ph\u00e1p th\u00f4ng th\u01b0\u1eddng.<\/td>\n<td style=\"width: 50%\">Vi\u00eam m\u00f4i, kh\u00f4 m\u00f4i, kh\u00f4 da, kh\u00f4 mi\u1ec7ng, kh\u00f4 m\u0169i v\u00e0 nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t \u1edf b\u1ec7nh nh\u00e2n d\u00f9ng isotretinoin.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">Isotretinoin \u0111\u01b0\u1eddng u\u1ed1ng l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1ed9c \u0111\u00e1o \u0111\u1ec3 ch\u1eefa kh\u1ecfi c\u00e1c tr\u01b0\u1eddng h\u1ee3p m\u1ee5n tr\u1ee9ng c\u00e1 v\u1eeba v\u00e0 n\u1eb7ng, ng\u0103n ng\u1eeba s\u1eb9o v\u00e0 t\u00e1c \u0111\u1ed9ng t\u00e2m l\u00fd x\u00e3 h\u1ed9i.<\/td>\n<td style=\"width: 50%\">Acnotin 20 c\u00f3 th\u1ec3 g\u00e2y n\u00ean nh\u1eefng d\u1ecb t\u1eadt b\u1ea9m sinh cho thai nhi.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">D\u1ea1ng vi\u00ean nang m\u1ec1m so v\u1edbi d\u1ea1ng kem b\u00f4i \u0111i\u1ec1u tr\u1ecb m\u1ee5n ti\u1ec7n s\u1eed d\u1ee5ng h\u01a1n, kh\u00f4ng ph\u1ea3i b\u00f4i l\u00ean da g\u00e2y nh\u1eddn r\u00edt, kh\u00f3 ch\u1ecbu.<\/td>\n<td style=\"width: 50%\"><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">Acnotin 20 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t tr\u00ean d\u00e2y chuy\u1ec1n c\u00f4ng ngh\u1ec7 hi\u1ec7n \u0111\u1ea1i, \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 \u0111\u1ea1t chu\u1ea9n GMP c\u1ee7a nh\u00e0 m\u00e1y Mega Lifesciences., Ltd.<\/td>\n<td style=\"width: 50%\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u00e1c gi\u1ea3 Hannah D. Pile v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 1 th\u00e1ng 5 n\u0103m 2023). <em>Isotretinoin<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 10 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30247824\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30247824\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 Edileia Bagatin v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 08 n\u0103m 2020). <em>The use of isotretinoin for acne &#8211; an update on optimal dosing, surveillance, and adverse effects<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 10 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32744074\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32744074\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 I A Vallerand v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 01 n\u0103m 2018). <em>Efficacy and adverse events of oral isotretinoin for acne: a systematic review<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 10 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28542914\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28542914\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Acnotin 20 ch\u1ee9a ho\u1ea1t ch\u1ea5t Isotretinoin v\u1edbi h\u00e0m l\u01b0\u1ee3ng 20mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00e1c tr\u01b0\u1eddng h\u1ee3p m\u1ee5n tr\u1ee9ng c\u00e1 n\u1eb7ng m\u00e0 d\u00f9ng c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb th\u00f4ng th\u01b0\u1eddng kh\u00f4ng hi\u1ec7u qu\u1ea3, <span style=\"font-weight: 400\">m\u1ee5n tr\u1ee9ng c\u00e1 k\u00e9o d\u00e0i l\u00e2u n\u0103m \u0111\u1ec3 l\u1ea1i nhi\u1ec1u s\u1eb9o x\u1ea5u, \u1ea3nh h\u01b0\u1edfng l\u1edbn \u0111\u1ebfn ngh\u1ec1 nghi\u1ec7p v\u00e0 t\u00e2m l\u00fd x\u00e3 h\u1ed9i.<\/span><\/p>\n","protected":false},"author":490,"featured_media":56193,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-56191","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/56191","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=56191"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/56193"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=56191"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=56191"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=56191"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}