{"id":55236,"date":"2023-11-06T08:14:33","date_gmt":"2023-11-06T01:14:33","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=55236"},"modified":"2025-07-24T13:59:46","modified_gmt":"2025-07-24T06:59:46","slug":"pharcavir-25mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/pharcavir-25mg\/","title":{"rendered":"Pharcavir 25mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/pharcavir-25mg\/\">Pharcavir 25mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1ea1i C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Trung \u01b0\u01a1ng I \u2013 Pharbaco, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD3-29-19<\/strong><\/p>\n<h2>Pharcavir 25mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean <strong>Pharcavir 25mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: Tenofovir alafenamide 25mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD3-29-19.<br \/>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<br \/>\nXu\u1ea5t x\u1ee9: Vi\u1ec7t Nam.<\/p>\n<h2>Thu\u1ed1c Pharcavir 25mg c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Tenofovir alafenamid l\u00e0 m\u1ed9t ti\u1ec1n ch\u1ea5t phosphoramid c\u1ee7a tenofovir. nh\u1edd Nh\u1edd s\u1ef1 khu\u1ebfch t\u00e1n th\u1ee5 \u0111\u1ed9ng v\u00e0 v\u1eadn chuy\u1ec3n qua c\u00e1c k\u00eanh h\u1ea5p thu \u1edf gan, Tenofovir alafenamid x\u00e2m nh\u1eadp t\u1ebf b\u00e0o gan nguy\u00ean ph\u00e1t. T\u1ea1i \u0111\u00e2y, nh\u1edd enzym carboxylesterase-1, Tenofovir alafenamid ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c th\u1ee7y ph\u00e2n th\u00e0nh tenofovir. Sau \u0111\u00f3, Tenofovir n\u1ed9i b\u00e0o \u0111\u01b0\u1ee3c phosphoryl h\u00f3a th\u00e0nh tenofovir diphosphat &#8211; ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh d\u01b0\u1ee3c l\u00fd. Tenofovir diphosphat g\u1eafn v\u00e0o ADN c\u1ee7a virus b\u1eb1ng enzym sao ch\u00e9p ng\u01b0\u1ee3c c\u1ee7a HBV, \u1ee9c ch\u1ebf s\u1ef1 nh\u00e2n l\u00ean c\u1ee7a virus vi\u00eam gan B d\u1eabn \u0111\u1ebfn k\u1ebft th\u00fac chu\u1ed7i ADN.<\/p>\n<p>Tenofovir c\u00f3 \u00e1i l\u1ef1c cao v\u1edbi virus vi\u00eam gan B, HIV-1 v\u00e0 HIV-2, \u1ee9c ch\u1ebf y\u1ebfu c\u00e1c ADN polymerase \u1edf \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa. Kh\u00f4ng c\u00f3 d\u1ea5u hi\u1ec7u v\u1ec1 \u0111\u1ed9c t\u00ednh ty th\u1ec3 trong c\u00e1c th\u1eed nghi\u1ec7m invitro.<\/p>\n<h3>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu<\/li>\n<\/ul>\n<p>Sau kho\u1ea3ng 0,48 gi\u1edd d\u00f9ng thu\u1ed1c v\u00e0o l\u00fac \u0111\u00f3i, thu\u1ed1c \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u1ee7a tenofovir v\u00e0 tenofovir alafenamid v\u00e0 \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh l\u1ea7n l\u01b0\u1ee3t l\u00e0 0,02 v\u00e0 0,18 ug\/ml. N\u1ed3ng \u0111\u1ed9 tenofovir alafenamid t\u0103ng 65% khi u\u1ed1ng li\u1ec1u \u0111\u01a1n c\u00f9ng v\u1edbi b\u1eefa \u0103n gi\u00e0u ch\u1ea5t b\u00e9o so v\u1edbi khi u\u1ed1ng l\u00fac \u0111\u00f3i.<\/p>\n<ul>\n<li>Ph\u00e2n b\u1ed1<\/li>\n<\/ul>\n<p>Kh\u1ea3 n\u0103ng g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 80%.<\/p>\n<ul>\n<li>Chuy\u1ec3n h\u00f3a<\/li>\n<\/ul>\n<p>D\u01b0\u1edbi t\u00e1c \u0111\u1ed9ng c\u1ee7a enzym carboxylesterase-1, Tenofovir alafenamid ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh tenofovir. Trong c\u01a1 th\u1ec3, tenofovir alafenamid th\u1ee7y ph\u00e2n t\u1ea1o th\u00e0nh tenofovir, sau \u0111\u00f3 \u0111\u01b0\u1ee3c phosphoryl h\u00f3a th\u00e0nh tenofovir diphosphat &#8211; ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh. Nghi\u00ean c\u1ee9u in vitro cho th\u1ea5y Pharcavir \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a r\u1ea5t \u00edt b\u1edfi CYP3A4.<\/p>\n<ul>\n<li>Th\u1ea3i tr\u1eeb<\/li>\n<\/ul>\n<p>D\u01b0\u1edbi 1% tenofovir alafenamid d\u01b0\u1edbi d\u1ea1ng ch\u01b0a \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua th\u1eadn. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh c\u1ee7a Tenofovir alafenamid v\u00e0 tenofovir l\u1ea7n l\u01b0\u1ee3t l\u00e0 0,51 v\u00e0 32,37 gi\u1edd. Tenofovir \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua th\u1eadn nh\u1edd qu\u00e1 tr\u00ecnh l\u1ecdc \u1edf c\u1ea7u th\u1eadn v\u00e0 b\u00e0i ti\u1ebft \u1edf \u1ed1ng th\u1eadn.<\/p>\n<h2>Thu\u1ed1c Pharcavir 25mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb vi\u00eam gan B m\u1ea1n \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 thi\u1ebfu ni\u00ean tr\u00ean 12 tu\u1ed5i v\u1edbi c\u00e2n n\u1eb7ng t\u1eeb 35 kg tr\u1edf l\u00ean.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Pharcavir 25mg<\/h2>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0o m\u1ed9t th\u1eddi \u0111i\u1ec3m trong ng\u00e0y, n\u00ean u\u1ed1ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n.<\/p>\n<p>&#8211; Trong v\u00f2ng 1 gi\u1edd sau khi u\u1ed1ng thu\u1ed1c, n\u1ebfu b\u1ec7nh nh\u00e2n n\u00f4n th\u00ec u\u1ed1ng b\u00f9 1 vi\u00ean thu\u1ed1c kh\u00e1c. N\u1ebfu h\u01a1n 1 gi\u1edd sau khi u\u1ed1ng thu\u1ed1c, b\u1ec7nh nh\u00e2n b\u1ecb n\u00f4n th\u00ec kh\u00f4ng c\u1ea7n u\u1ed1ng b\u00f9 vi\u00ean thu\u1ed1c kh\u00e1c.<\/p>\n<p>&#8211; N\u1ebfu b\u1ec7nh nh\u00e2n qu\u00ean u\u1ed1ng thu\u1ed1c trong th\u1eddi gian &lt; 18 gi\u1edd th\u00ec u\u1ed1ng lu\u00f4n ngay khi nh\u1edb ra v\u00e0 u\u1ed1ng li\u1ec1u ti\u1ebfp theo nh\u01b0 b\u00ecnh th\u01b0\u1eddng. N\u1ebfu th\u1eddi gian &gt; 18 gi\u1edd th\u00ec u\u1ed1ng li\u1ec1u ti\u1ebfp theo nh\u01b0 b\u00ecnh th\u01b0\u1eddng, kh\u00f4ng u\u1ed1ng li\u1ec1u \u0111\u00e3 qu\u00ean.<\/p>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>1 vi\u00ean\/l\u1ea7n x 1 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Ng\u01b0ng \u0111i\u1ec1u tr\u1ecb<\/p>\n<p>&#8211; B\u1ec7nh nh\u00e2n HBeAg (+), kh\u00f4ng x\u01a1 gan: \u0110i\u1ec1u tr\u1ecb ph\u1ea3i k\u00e9o d\u00e0i cho \u0111\u1ebfn khi HBeAg \u00e2m t\u00ednh ho\u1eb7c t\u1edbi khi c\u00f3 huy\u1ebft thanh chuy\u1ec3n \u0111\u1ed5i HBs ho\u1eb7c \u0111\u1ebfn khi th\u1ea5y thu\u1ed1c kh\u00f4ng c\u00f2n t\u00e1c d\u1ee5ng. \u0110\u00e1nh gi\u00e1 l\u1ea1i th\u01b0\u1eddng xuy\u00ean sau khi ng\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>&#8211; B\u1ec7nh nh\u00e2n HBeAg (-), kh\u00f4ng x\u01a1 gan: \u0110i\u1ec1u tr\u1ecb cho \u0111\u1ebfn khi huy\u1ebft thanh chuy\u1ec3n \u0111\u1ed5i HBs ho\u1eb7c \u0111\u1ebfn khi th\u1ea5y thu\u1ed1c kh\u00f4ng c\u00f2n t\u00e1c d\u1ee5ng. V\u1edbi \u0111i\u1ec1u tr\u1ecb &gt; 2 n\u0103m, n\u00ean \u0111\u00e1nh gi\u00e1 l\u1ea1i th\u01b0\u1eddng xuy\u00ean \u0111\u1ec3 ch\u1ee9ng minh li\u1ec7u ph\u00e1p v\u1eabn c\u00f2n th\u00edch h\u1ee3p cho b\u1ec7nh nh\u00e2n.<\/p>\n<p>B\u1ec7nh nh\u00e2n t\u1eeb 65 tu\u1ed5i tr\u1edf l\u00ean: Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy th\u1eadn c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin \u2265 15 ml\/ph\u00fat ho\u1eb7c b\u1ec7nh nh\u00e2n th\u1ea9m t\u00e1ch m\u00e1u v\u00e0 c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin &lt; 15 ml\/ph\u00fat: Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/p>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin &lt; 15 ml\/ph\u00fat v\u00e0 kh\u00f4ng th\u1ea9m t\u00e1ch m\u00e1u, kh\u00f4ng c\u00f3 m\u1ee9c khuy\u1ebfn c\u00e1o.<\/p>\n<p>Suy gan: Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/p>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u d\u00f9ng thu\u1ed1c cho tr\u1ebb em &lt; 12 tu\u1ed5i ho\u1eb7c c\u00e2n n\u1eb7ng &lt; 35kg.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Pharcavir 25mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>M\u1eabn c\u1ea3m v\u1edbi ho\u1ea1t ch\u1ea5t tenofovir alafenamid fumarat ho\u0103\u0323c b\u1ea5t c\u01b0\u0301 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Pharcavir 25mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Pharcavir kh\u00f4ng ng\u0103n ng\u1eeba l\u00e2y truy\u1ec1n vi\u00eam gan B v\u00ec v\u1eady ph\u1ea3i ti\u1ebfp t\u1ee5c s\u1eed d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba th\u00edch h\u1ee3p.<\/p>\n<p>B\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh gan m\u1ea5t b\u00f9 c\u00f3 nguy c\u01a1 cao g\u1eb7p c\u00e1c ph\u1ea3n \u1ee9ng ph\u1ee5 nghi\u00eam tr\u1ecdng tr\u00ean gan ho\u1eb7c th\u1eadn, c\u1ea7n theo d\u00f5i c\u00e1c th\u00f4ng s\u1ed1 v\u1ec1 gan v\u00e0 th\u1eadn th\u01b0\u1eddng xuy\u00ean.<\/p>\n<p>Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, b\u1ec7nh vi\u00eam gan B m\u1ea1n t\u00ednh c\u00f3 th\u1ec3 n\u1eb7ng th\u00eam, v\u00ec v\u1eady c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb. M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng g\u1eb7p ph\u1ea3i sau khi ng\u1eebng \u0111i\u1ec1u tr\u1ecb, v\u00ec v\u1eady c\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng gan \u00edt nh\u1ea5t 6 th\u00e1ng sau ng\u01b0ng \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B.<br \/>\nCh\u01b0a c\u00f3 d\u1eef li\u1ec7u an to\u00e0n v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng Pharcavir \u1edf b\u1ec7nh nh\u00e2n c\u00f3 Clcr &lt; 30 ml\/ph\u00fat. Nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 Clcr &lt; 15 ml\/ph\u00fat v\u00e0 kh\u00f4ng \u0111\u01b0\u1ee3c th\u1ea9m t\u00e1ch m\u00e1u th\u00ec kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng Pharavir.<\/p>\n<p>N\u00ean tu\u00e2n \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi vi\u00eam gan C theo h\u01b0\u1edbng d\u1eabn.<\/p>\n<p>Tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi Pharcavir, c\u1ea7n th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m kh\u00e1ng th\u1ec3 HIV cho b\u1ec7nh nh\u00e2n nhi\u1ec5m HBV. Pharcavir ph\u1ea3i \u0111\u01b0\u1ee3c ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng virus kh\u00e1c \u1edf b\u1ec7nh nh\u00e2n nhi\u1ec5m \u0111\u1ed3ng th\u1eddi HBV v\u00e0 HIV.<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi Pharcavir v\u1edbi m\u1ed9t s\u1ed1 thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh, c\u00e1c s\u1ea3n ph\u1ea9m c\u00f3 ch\u1ee9a tenofovir alafenamid, adefovir dipivoxil, tenofovir disoproxil fumarat, thu\u1ed1c kh\u00e1ng khu\u1ea9n, ch\u1ea5t g\u00e2y c\u1ea3m \u1ee9ng P-glycoprotein.<\/p>\n<p>B\u1ec7nh nh\u00e2n thi\u1ebfu enzym Lapp lactase, c\u00f3 b\u1ec7nh l\u00fd di truy\u1ec1n hi\u1ebfm g\u1eb7p kh\u00f4ng dung n\u1ea1p galactose, k\u00e9m h\u1ea5p thu glucose-galactose kh\u00f4ng n\u00ean d\u00f9ng Pharcavir 25mg.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<table style=\"border-collapse: collapse;width: 100%;height: 211px\">\n<tbody>\n<tr style=\"height: 21px\">\n<td style=\"width: 16.2237%;height: 21px;text-align: center\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/td>\n<td style=\"width: 30.5093%;height: 21px;text-align: center\">C\u01a1 quan<\/td>\n<td style=\"width: 53.2669%;height: 21px;text-align: center\">Bi\u1ec3u hi\u1ec7n<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 16.2237%;height: 21px\">R\u1ea5t ph\u1ed5 bi\u1ebfn<\/td>\n<td style=\"width: 30.5093%;height: 21px\">Th\u1ea7n kinh<\/td>\n<td style=\"width: 53.2669%;height: 21px\">Nh\u1ee9c \u0111\u1ea7u<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 16.2237%;height: 21px\" rowspan=\"6\">Ph\u1ed5 bi\u1ebfn<\/td>\n<td style=\"width: 30.5093%;height: 21px\">Th\u1ea7n kinh<\/td>\n<td style=\"width: 53.2669%;height: 21px\">Ch\u00f3ng m\u1eb7t<\/td>\n<\/tr>\n<tr style=\"height: 64px\">\n<td style=\"width: 30.5093%;height: 64px\">Ti\u00eau h\u00f3a<\/td>\n<td style=\"width: 53.2669%;height: 64px\">Ti\u00eau ch\u1ea3y, n\u00f4n m\u1eeda, bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng, tr\u01b0\u1edbng b\u1ee5ng, \u0111\u1ea7y h\u01a1i<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 30.5093%;height: 21px\">Gan m\u1eadt<\/td>\n<td style=\"width: 53.2669%;height: 21px\">T\u0103ng ALT<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 30.5093%;height: 21px\">Da v\u00e0 c\u00e1c bi\u1ec3u b\u00ec d\u01b0\u1edbi da<\/td>\n<td style=\"width: 53.2669%;height: 21px\">Ph\u00e1t ban, ng\u1ee9a<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 30.5093%;height: 21px\">C\u01a1 x\u01b0\u01a1ng v\u00e0 m\u00f4 li\u00ean k\u1ebft<\/td>\n<td style=\"width: 53.2669%;height: 21px\">\u0110au kh\u1edbp<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 30.5093%;height: 21px\">R\u1ed1i lo\u1ea1n chung<\/td>\n<td style=\"width: 53.2669%;height: 21px\">M\u1ec7t m\u1ecfi<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Kh\u00f4ng ph\u1ed1i h\u1ee3p Pharcavir v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m c\u00f3 ch\u1ee9a tenofovir alafenamid, tenofovir disoproxil fumarat, ho\u1eb7c adefovir dipivoxil.<\/p>\n<p>C\u00e1c thu\u1ed1c g\u00e2y c\u1ea3m \u1ee9ng P-gp (v\u00ed d\u1ee5 nh\u01b0 rifapentin, rifampicin, carbamazepin, rifabutin, phenobarbital ho\u1eb7c th\u1ea3o d\u01b0\u1ee3c. St. John&#8217;s wort) c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 tenofovir alafenamid, gi\u1ea3m t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a thu\u1ed1c, v\u00ec v\u1eady tr\u00e1nh d\u00f9ng c\u00f9ng v\u1edbi Pharcavir.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a tenofovir alafenamid c\u00f3 th\u1ec3 t\u0103ng khi d\u00f9ng v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf P-gp v\u00e0\/ho\u1eb7c BCRP.<\/p>\n<p>Ho\u1ea1t t\u00ednh c\u1ee7a OATP1B1 v\u00e0\/ho\u1eb7c OATP1B3 c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 ph\u00e2n b\u1ed1 c\u1ee7a tenofovir alafenamid trong c\u01a1 th\u1ec3.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n<p>C\u00f3 th\u1ec3 xem x\u00e9t s\u1eed d\u1ee5ng Pharcavir 25mg \u1edf ph\u1ee5 n\u1eef mang thai n\u1ebfu c\u1ea7n thi\u1ebft.<\/p>\n<p>Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng Pharcavir 25mg trong th\u1eddi k\u00ec cho con b\u00fa.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 qu\u00e1 li\u1ec1u. Khi qu\u00e1 li\u1ec1u c\u1ea7n theo d\u00f5i v\u00e0 \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 chung. Th\u1ea9m t\u00e1ch m\u00e1u c\u00f3 th\u1ec3 c\u00f3 t\u00e1c d\u1ee5ng.<\/p>\n<h3>T\u00e1c \u0111\u1ed9ng tr\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng nhi\u1ec1u \u0111\u1ebfn ho\u1ea1t \u0111\u1ed9ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h2>Thu\u1ed1c Pharcavir 25mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Pharcavir 25mg<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/bastevir-0-5mg\/#:~:text=Thu%E1%BB%91c%20Entecavir%20Stada%20l%C3%A0%20thu%E1%BB%91c,3%20v%E1%BB%89%20x%2010%20vi%C3%AAn.\">Bastevir 0.5mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m H\u00e0 T\u00e2y, ch\u1ee9a Entecavir h\u00e0m l\u01b0\u1ee3ng 0.5mg. Thu\u1ed1c d\u00f9ng \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh vi\u00eam gan m\u1ea1n t\u00ednh (HBV) \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 2 tu\u1ed5i. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n bao phim, v\u1edbi ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb v\u1ecb th\u00e0nh ni\u00ean \u2265 16 tu\u1ed5i c\u00f3 th\u1ec3 u\u1ed1ng 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y. Thu\u1ed1c c\u00f3 gi\u00e1 180.000 \u0111\u1ed3ng\/ 1 h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/pentovas-25mg\/\">Pentovas 25mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n SPM ch\u1ee9a Tenofovir alafenamid 25mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m virus vi\u00eam gan B m\u1ea1n t\u00ednh \u1edf b\u1ec7nh nh\u00e2n x\u01a1 gan c\u00f2n b\u00f9. Thu\u1ed1c c\u00f3 d\u1ea1ng vi\u00ean n\u00e9n bao phim v\u00e0 c\u00f3 gi\u00e1 800.000 \u0111\u1ed3ng\/ 1 H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<\/p>\n<h2>T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Pharcavir 25mg?<\/h2>\n<table style=\"border-collapse: collapse;width: 100%;height: 127px\">\n<tbody>\n<tr style=\"height: 21px\">\n<td style=\"width: 50%;height: 21px;text-align: center\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 50%;height: 21px;text-align: center\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr style=\"height: 43px\">\n<td style=\"width: 50%;height: 43px\">Tenofovir alafenamide l\u00e0 m\u1ed9t trong nh\u1eefng bi\u1ec7n ph\u00e1p can thi\u1ec7p ch\u00ednh \u0111\u1ec3 h\u1ea1n ch\u1ebf nhi\u1ec5m HBV.<\/td>\n<td style=\"width: 50%;height: 43px\">T\u00e1c d\u1ee5ng ph\u1ee5 nh\u1ee9c \u0111\u1ea7u r\u1ea5t th\u01b0\u1eddng g\u1eb7p khi d\u00f9ng thu\u1ed1c.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 50%;height: 21px\">Li\u1ec1u d\u00f9ng \u0111\u01a1n gi\u1ea3n, ch\u1ec9 1 vi\u00ean\/ng\u00e0y, thu\u1ed1c kh\u1edfi ph\u00e1t t\u00e1c d\u1ee5ng nhanh.<\/td>\n<td style=\"width: 50%;height: 21px\">Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 s\u1eed d\u1ee5ng thu\u1ed1c cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 50%;height: 21px\">B\u1ec7nh nh\u00e2n suy gan kh\u00f4ng c\u1ea7n thay \u0111\u1ed5i li\u1ec1u.<\/td>\n<td style=\"width: 50%;height: 21px\"><\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 50%;height: 21px\">Pharcavir 25mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Trung \u01b0\u01a1ng I \u2013 Pharbaco &#8211; m\u1ed9t trong nh\u1eefng c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m h\u00e0ng \u0111\u1ea7u Vi\u1ec7t Nam v\u1edbi nh\u00e0 m\u00e1y \u0111\u1ea1t chu\u1ea9n GMP.<\/td>\n<td style=\"width: 50%;height: 21px\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u00e1c gi\u1ea3 Giovanni Di Perri (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 01 th\u00e1ng 12 n\u0103m 2020). <em>Tenofovir alafenamide revisited<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 06 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33257626\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33257626\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 Michael R Charlton v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 9 n\u0103m 2020). <em>An expert review on the use of tenofovir alafenamide for the treatment of chronic hepatitis B virus infection in Asia<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 06 th\u00e1ng 11 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32666200\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32666200\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 Kwan Soo Byun. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 02 n\u0103m 2022). <em>Tenofovir Alafenamide for Drug-Resistant Hepatitis B: A Randomized Trial for Switching From Tenofovir Disoproxil Fumarate<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 06 th\u00e1ng 11 n\u0103m 2023, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33962041\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33962041\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Pharcavir 25mg ch\u1ee9a ho\u1ea1t ch\u1ea5t Tenofovir alafenamide v\u1edbi h\u00e0m l\u01b0\u1ee3ng 25mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B m\u1ea1n \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 thi\u1ebfu ni\u00ean tr\u00ean 12 tu\u1ed5i v\u1edbi c\u00e2n n\u1eb7ng t\u1eeb 35 kg tr\u1edf l\u00ean<\/p>\n","protected":false},"author":490,"featured_media":55238,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-55236","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/55236","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=55236"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/55238"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=55236"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=55236"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=55236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}