{"id":53068,"date":"2023-10-30T11:26:32","date_gmt":"2023-10-30T04:26:32","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=53068"},"modified":"2025-07-24T13:59:52","modified_gmt":"2025-07-24T06:59:52","slug":"esogas-tiem-bidiphar","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/esogas-tiem-bidiphar\/","title":{"rendered":"Esogas ti\u00eam Bidiphar"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Esogas Bidiphar<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c-TTBYT B\u00ecnh \u0110\u1ecbnh (Bidiphar), c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-29952-18.<\/b><\/p>\n

Esogas l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n
Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n
Thu\u1ed1c <\/span>Esogas ti\u00eam<\/b> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n
Esomeprazol \u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026.. 40mg<\/span><\/p>\n
T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 l\u1ecd.<\/span><\/p>\n
\u1ed0ng dung m\u00f4i g\u1ed3m NaCl v\u00e0 n\u01b0\u1edbc c\u1ea5t pha ti\u00eam v\u1eeba \u0111\u1ee7 5ml<\/span><\/p>\n
D\u1ea1ng b\u00e0o ch\u1ebf: B\u1ed9t \u0111\u00f4ng kh\u00f4 pha ti\u00eam<\/span><\/p>\n
Tr\u00ecnh b\u00e0y<\/span><\/h3>\n
S\u0110K: VD-29952-18<\/span><\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd + 1 \u1ed1ng dung m\u00f4i 5ml<\/span><\/p>\n
Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/span><\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Esogas Bidiphar<\/span><\/h2>\n\n\n\n\n\n\n\n\n
\u0110\u1eb7c \u0111i\u1ec3m<\/i><\/td>\n Esomeprazol<\/i><\/td>\n<\/tr>\n
C\u01a1 ch\u1ebf<\/td>\n \n
\n
Esomeprazol l\u00e0 d\u1ea1ng \u0111\u1ed3ng ph\u00e2n S c\u1ee7a omeprazol, \u0111\u01b0\u1ee3c d\u00f9ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 omeprazol trong \u0111i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y \u2013 t\u00e1 tr\u00e0ng, b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n v\u00e0 h\u1ed9i ch\u1ee9ng Zollinger \u2013 Ellison.<\/li>\n
Esomeprazol g\u1eafn v\u1edbi H+\/K+-ATPase \u1edf t\u1ebf b\u00e0o th\u00e0nh d\u1ea1 d\u00e0y, l\u00e0m b\u1ea5t ho\u1ea1t h\u1ec7 th\u1ed1ng enzym n\u00e0y, ng\u0103n c\u1ea3n b\u01b0\u1edbc cu\u1ed1i c\u00f9ng c\u1ee7a s\u1ef1 b\u00e0i ti\u1ebft acid hydroclorid v\u00e0o l\u00f2ng d\u1ea1 d\u00e0y. V\u00ec v\u1eady esomeprazol c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf d\u1ea1 d\u00e0y ti\u1ebft l\u01b0\u1ee3ng acid c\u01a1 b\u1ea3n v\u00e0 c\u1ea3 khi b\u1ecb k\u00edch th\u00edch do b\u1ea5t k\u1ef3 t\u00e1c nh\u00e2n n\u00e0o. Thu\u1ed1c t\u00e1c d\u1ee5ng m\u1ea1nh, k\u00e9o d\u00e0i.<\/li>\n
C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf nh\u01b0ng kh\u00f4ng ti\u1ec7t tr\u1eeb \u0111\u01b0\u1ee3c Helicobacter pylori, n\u00ean ph\u1ea3i ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c kh\u00e1ng sinh (nh\u01b0 amoxicillin, tetracyclin v\u00e0 clarithromycin) m\u1edbi c\u00f3 th\u1ec3 ti\u1ec7t tr\u1eeb hi\u1ec7u qu\u1ea3 vi khu\u1ea9n n\u00e0y.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/td>\n H\u1ea5p thu<\/td>\n Sau khi u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng (Cmax) \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 1,5 gi\u1edd (Tmax). Cmax t\u0103ng t\u1ef7 l\u1ec7 thu\u1eadn khi t\u0103ng li\u1ec1u v\u00e0 di\u1ec7n t\u00edch d\u01b0\u1edbi \u0111\u01b0\u1eddng cong n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng theo th\u1eddi gian (AUC) t\u0103ng g\u1ea5p ba l\u1ea7n t\u1eeb 20 \u0111\u1ebfn 40 mg.<\/td>\n<\/tr>\n
Ph\u00e2n b\u1ed1<\/td>\n Esomeprazole li\u00ean k\u1ebft 97% v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. Li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kh\u00f4ng \u0111\u1ed5i trong kho\u1ea3ng n\u1ed3ng \u0111\u1ed9 t\u1eeb 2 \u0111\u1ebfn 20 umol\/L. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 bi\u1ec3u ki\u1ebfn \u200b\u200b\u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh \u1edf ng\u01b0\u1eddi t\u00ecnh nguy\u1ec7n kh\u1ecfe m\u1ea1nh l\u00e0 kho\u1ea3ng 16 L.<\/td>\n<\/tr>\n
Chuy\u1ec3n h\u00f3a<\/td>\n Esomeprazole \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan nh\u1edd h\u1ec7 th\u1ed1ng enzym cytochrome P450 (CYP). C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a esomeprazole kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng ti\u1ebft. Ph\u1ea7n l\u1edbn qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a c\u1ee7a esomeprazole ph\u1ee5 thu\u1ed9c v\u00e0o isoenzym CYP2C19, ch\u1ea5t t\u1ea1o th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a hydroxy v\u00e0 desmethyl. L\u01b0\u1ee3ng c\u00f2n l\u1ea1i ph\u1ee5 thu\u1ed9c v\u00e0o CYP3A4 \u0111\u1ec3 t\u1ea1o th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a sulphone.<\/td>\n<\/tr>\n
Th\u1ea3i tr\u1eeb<\/td>\n Th\u1eddi gian b\u00e1n th\u1ea3i trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a esomeprazole kho\u1ea3ng 1 \u0111\u1ebfn 1,5 gi\u1edd. \u00cdt h\u01a1n 1% thu\u1ed1c g\u1ed1c \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Thu\u1ed1c Esogas Bidiphar \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n
Esogas Bidiphar l\u00e0 <\/span>thu\u1ed1c ti\u00eam gi\u1ea3m \u0111au d\u1ea1 d\u00e0y<\/b> \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p:<\/span><\/p>\n
Ng\u01b0\u1eddi l\u1edbn:<\/span><\/i><\/p>\n
\u0110i\u1ec1u tr\u1ecb kh\u00e1ng ti\u1ebft acid d\u1ea1 d\u00e0y khi ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb \u0111\u01b0\u1eddng u\u1ed1ng kh\u00f4ng hi\u1ec7u qu\u1ea3, bao g\u1ed3m tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y – th\u1ef1c qu\u1ea3n; lo\u00e9t d\u1ea1 d\u00e0y do d\u00f9ng Nsaids; d\u1ef1 ph\u00f2ng lo\u00e9t d\u1ea1 d\u00e0y v\u00e0 t\u00e1 tr\u00e0ng do d\u00f9ng Nsaids \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1.<\/span><\/p>\n
Ph\u00f2ng ng\u1eeba t\u00e1i xu\u1ea5t huy\u1ebft sau khi \u0111i\u1ec1u tr\u1ecb n\u1ed9i soi\u00a0 xu\u1ea5t huy\u1ebft c\u1ea5p t\u00ednh do lo\u00e9t d\u1ea1 d\u00e0y ho\u1eb7c t\u00e1 tr\u00e0ng.<\/span><\/p>\n
Tr\u1ebb em v\u00e0 tr\u1ebb v\u1ecb th\u00e0nh ni\u00ean t\u1eeb 1 – 18 tu\u1ed5i:<\/span><\/i><\/p>\n
\u0110i\u1ec1u tr\u1ecb kh\u00e1ng ti\u1ebft acid d\u1ea1 d\u00e0y khi ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng kh\u00f4ng \u0111\u00e1p \u1ee9ng, nh\u01b0: b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n (GERD) \u1edf b\u1ec7nh nh\u00e2n b\u1ecb vi\u00eam th\u1ef1c qu\u1ea3n b\u00e0o m\u00f2n do tr\u00e0o ng\u01b0\u1ee3c v\u00e0\/ho\u1eb7c c\u00e1c tri\u1ec7u ch\u1ee9ng tr\u00e0o ng\u01b0\u1ee3c n\u1eb7ng<\/span><\/p>\n
Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Esogas Bidiphar<\/span><\/h2>\n
C\u00e1ch d\u00f9ng<\/span><\/h3>\n
\u0110\u1ed1i v\u1edbi ti\u00eam t\u0129nh m\u1ea1ch<\/span><\/i><\/p>\n
Dung d\u1ecbch ti\u00eam \u0111\u01b0\u1ee3c pha ch\u1ebf b\u1eb1ng c\u00e1ch ho\u00e0n nguy\u00ean l\u1ecd b\u1ed9t v\u1edbi 5 ml dung d\u1ecbch NaCl 0,9%. Ti\u00eam t\u0129nh m\u1ea1ch ch\u1eadm \u00edt nh\u1ea5t 3 ph\u00fat.<\/span><\/p>\n
\u0110\u1ed1i v\u1edbi truy\u1ec1n t\u0129nh m\u1ea1ch<\/span><\/i><\/p>\n
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Dung d\u1ecbch truy\u1ec1n t\u0129nh m\u1ea1ch (li\u1ec1u 40mg) trong 10 \u2013 30 ph\u00fat: ho\u00e0n nguy\u00ean l\u1ecd b\u1ed9t v\u1edbi 5 ml dung d\u1ecbch NaCl 0,9% ho\u1eb7c dung d\u1ecbch Lactated Ringer ho\u1eb7c dung d\u1ecbch Dextrose 5%. Sau \u0111\u00f3 pha lo\u00e3ng t\u1edbi th\u1ec3 t\u00edch 100 ml.<\/span><\/li>\n
Dung d\u1ecbch truy\u1ec1n t\u0129nh m\u1ea1ch (li\u1ec1u 80mg): ho\u00e0n nguy\u00ean 2 l\u1ecd b\u1ed9t 40 mg, m\u1ed7i l\u1ecd v\u1edbi 5 ml dung d\u1ecbch NaCl 0,9%. Sau \u0111\u00f3, dung d\u1ecbch trong 2 l\u1ecd \u0111\u01b0\u1ee3c pha lo\u00e3ng th\u00eam trong 100 ml dung d\u1ecbch NaCl 0,9%. Dung d\u1ecbch sau khi pha ch\u1ebf \u0111\u01b0\u1ee3c truy\u1ec1n trong th\u1eddi gian ho\u1eb7c t\u1ed1c \u0111\u1ed9 t\u01b0\u01a1ng \u1ee9ng nh\u01b0 trong ph\u1ea7n \u201cLi\u1ec1u l\u01b0\u1ee3ng\u201d.<\/span><\/li>\n<\/ul>\n
Dung d\u1ecbch sau khi pha trong su\u1ed1t, kh\u00f4ng m\u00e0u ho\u1eb7c v\u00e0ng nh\u1ea1t.<\/span><\/p>\n
Ch\u1ec9 s\u1eed d\u1ee5ng dung d\u1ecbch trong su\u1ed1t v\u00ec v\u1eady dung d\u1ecbch \u0111\u00e3 pha ph\u1ea3i ki\u1ec3m tra b\u1eb1ng m\u1eaft th\u01b0\u1eddng \u0111\u1ec3 ph\u00e1t hi\u1ec7n c\u00e1c ph\u00e2n t\u1eed l\u1ea1 v\u00e0 s\u1ef1 bi\u1ebfn m\u00e0u tr\u01b0\u1edbc khi d\u00f9ng.<\/span><\/p>\n
Dung d\u1ecbch \u0111\u00e3 pha kh\u00f4ng n\u00ean pha tr\u1ed9n ho\u1eb7c d\u00f9ng chung b\u1ed9 d\u00e2y truy\u1ec1n v\u1edbi c\u00e1cthu\u1ed1c kh\u00e1c.<\/span><\/p>\n
N\u00ean d\u00f9ng n\u1eeda th\u1ec3 t\u00edch pha n\u1ebfu ch\u1ec9 c\u1ea7n d\u00f9ng 20 mg esomeprazol, n\u00ean b\u1ecf ph\u1ea7n dung d\u1ecbch kh\u00f4ng s\u1eed d\u1ee5ng.<\/span><\/p>\n
Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb b\u1eb1ng \u0111\u01b0\u1eddng ti\u00eam th\u01b0\u1eddng ng\u1eafn, n\u00ean chuy\u1ec3n sang \u0111\u01b0\u1eddng u\u1ed1ng khi \u0111\u00e1p \u1ee9ng \u0111\u01b0\u1ee3c.<\/span><\/p>\n
Li\u1ec1u d\u00f9ng<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u0110\u1ed1i t\u01b0\u1ee3ng<\/i><\/td>\n Li\u1ec1u d\u00f9ng<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi l\u1edbn<\/i><\/td>\n \u0110i\u1ec1u tr\u1ecb kh\u00e1ng ti\u1ebft acid d\u1ea1 d\u00e0y khi li\u1ec7u ph\u00e1p \u0111\u01b0\u1eddng u\u1ed1ng kh\u00f4ng th\u00edch h\u1ee3p<\/td>\n V\u1edbi b\u1ec7nh nh\u00e2n vi\u00eam tr\u00e0o ng\u01b0\u1ee3c th\u1ef1c qu\u1ea3n: ti\u00eam 40mg, 1 l\u1ea7n\/ng\u00e0y. \u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng: 20mg, 1 l\u1ea7n\/ng\u00e0y.<\/p>\n
Ph\u00f2ng ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb vi\u00eam lo\u00e9t do d\u00f9ng Nsaids: ti\u00eam 20mg, 1 l\u1ea7n\/ng\u00e0y.<\/td>\n<\/tr>\n
Ph\u00f2ng ng\u1eeba t\u00e1i xu\u1ea5t huy\u1ebft do lo\u00e9t d\u1ea1 d\u00e0y v\u00e0 t\u00e1 tr\u00e0ng<\/td>\n Sau khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng n\u1ed9i soi xu\u1ea5t huy\u1ebft c\u1ea5p t\u00ednh do lo\u00e9t d\u1ea1 d\u00e0y ho\u1eb7c lo\u00e9t t\u00e1 tr\u00e0ng, truy\u1ec1n li\u1ec1u cao 80mg trong kho\u1ea3ng th\u1eddi gian 30 ph\u00fat, ti\u1ebfp theo truy\u1ec1n t\u0129nh m\u1ea1ch li\u00ean t\u1ee5c 8mg\/gi\u1edd trong 3 ng\u00e0y (72 gi\u1edd).<\/td>\n<\/tr>\n
Tr\u1ebb em<\/i><\/td>\n <\/td>\n \u0110i\u1ec1u tr\u1ecb vi\u00eam th\u1ef1c qu\u1ea3n b\u00e0o m\u00f2n do tr\u00e0o ng\u01b0\u1ee3c<\/td>\n \u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng c\u1ee7a GERD<\/td>\n<\/tr>\n
1 – 11 tu\u1ed5i<\/td>\n N\u1eb7ng < 20kg: 10mg, 1 l\u1ea7n\/ng\u00e0y.<\/p>\n
N\u1eb7ng \u2265 20kg: 10 ho\u1eb7c 20mg, 1 l\u1ea7n\/ng\u00e0y<\/td>\n
10mg, 1 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n
12 – 18 tu\u1ed5i<\/td>\n 40mg, 1 l\u1ea7n\/ng\u00e0y<\/td>\n 20mg, 1 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n
\u0110\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t<\/i><\/td>\n<\/tr>\n
Ng\u01b0\u1eddi suy th\u1eadn<\/td>\n Kh\u00f4ng c\u1ea7n gi\u1ea3m li\u1ec1u nh\u01b0ng c\u1ea9n tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng.<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi cao tu\u1ed5i<\/td>\n Kh\u00f4ng c\u1ea7n gi\u1ea3m li\u1ec1u<\/td>\n<\/tr>\n
Suy gan<\/td>\n GERD<\/td>\n Kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n suy gan nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh. \u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy gan n\u1eb7ng, kh\u00f4ng d\u00f9ng qu\u00e1 20mg m\u1ed7i ng\u00e0y.<\/td>\n<\/tr>\n
Lo\u00e9t xu\u1ea5t huy\u1ebft<\/td>\n Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u1edf b\u1ec7nh nh\u00e2n suy gan nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh. \u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy gan n\u1eb7ng, kh\u1edfi \u0111\u1ea7u n\u00ean truy\u1ec1n li\u1ec1u cao 80mg, ti\u1ebfp theo truy\u1ec1n t\u0129nh m\u1ea1ch li\u00ean t\u1ee5c li\u1ec1u 4 mg\/h trong 71,5 gi\u1edd c\u00f3 th\u1ec3 \u0111\u1ee7 \u0111\u1ec3 \u0111\u1ea1t hi\u1ec7u qu\u1ea3.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Esogas Bidiphar trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n
Kh\u00f4ng d\u00f9ng trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c ho\u1eb7c c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton kh\u00e1c.<\/span><\/p>\n
Kh\u00f4ng d\u00f9ng v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng nelfinavir.<\/span><\/p>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Esogas Bidiphar<\/span><\/h2>\n
Th\u1eadn tr\u1ecdng<\/span><\/h3>\n
C\u1ea7n lo\u1ea1i tr\u1eeb kh\u1ea3 n\u0103ng \u00e1c t\u00ednh do trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng esomeprazol c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng v\u00e0 ch\u1eadm qu\u00e1 tr\u00ecnh chu\u1ea9n \u0111o\u00e1n.<\/span><\/p>\n
Nguy c\u01a1 nhi\u1ec5m khu\u1ea9n c\u00f3 th\u1ec3 t\u0103ng nh\u1eb9 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb thu\u1ed1c.<\/span><\/p>\n
N\u1ebfu \u0111i\u1ec1u tr\u1ecb d\u00e0i h\u1ea1n (tr\u00ean 6 th\u00e1ng) c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m h\u1ea5p thu vitamin B12 go gi\u1ea3m \u0111\u1ed9 acid d\u1ea1 d\u00e0y.<\/span><\/p>\n
Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng <\/span>esomeprazol <\/b>kho\u1ea3ng 3 th\u00e1ng c\u00f3 th\u1ec3 b\u1ecb h\u1ea1 magie huy\u1ebft nghi\u00eam tr\u1ecdng v\u00e0 trong h\u1ea7u h\u1ebft c\u00e1c tr\u01b0\u1eddng h\u1ee3p s\u1eed d\u1ee5ng PPI trong v\u00f2ng 1 n\u0103m.<\/span><\/p>\n
Nguy c\u01a1 g\u00e3y x\u01b0\u01a1ng ch\u1eadu, x\u01b0\u01a1ng c\u1ed5 tay ho\u1eb7c c\u1ed9t s\u1ed1ng do lo\u00e3ng x\u01b0\u01a1ng c\u00f3 th\u1ec3 t\u0103ng do s\u1eed d\u1ee5ng li\u1ec1u cao ho\u1eb7c \u0111i\u1ec1u tr\u1ecb esomeprazol h\u01a1n 1 n\u0103m<\/span><\/p>\n
R\u1ea5t hi\u1ebfm g\u1eb7p c\u00e1c tr\u01b0\u1eddng h\u1ee3p SCLE li\u00ean quan \u0111\u1ebfn c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton.<\/span><\/p>\n
Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng esomeprazol cho ng\u01b0\u1eddi b\u1ecb b\u1ec7nh gan, ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa.<\/span><\/p>\n
D\u00f9ng esomeprazol k\u00e9o d\u00e0i c\u00f3 th\u1ec3 g\u00e2y vi\u00eam teo d\u1ea1 d\u00e0y ho\u1eb7c t\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n (nh\u01b0 vi\u00eam ph\u1ed5i m\u1eafc ph\u1ea3i t\u1ea1i c\u1ed9ng \u0111\u1ed3ng).<\/span><\/p>\n
C\u00f3 th\u1ec3 t\u0103ng nguy c\u01a1 ti\u00eau ch\u1ea3y do Clostridium dificile khi d\u00f9ng c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton.<\/span><\/p>\n
Esogas ch\u1ee9a < 1 mmol ion natri (23 mg) trong m\u1ed7i l\u1ecd b\u1ed9t \u0111\u00f4ng kh\u00f4, ngh\u0129a l\u00e0 v\u1ec1 c\u01a1 b\u1ea3n kh\u00f4ng c\u00f3 natri.<\/span><\/p>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
C\u01a1 quan<\/span><\/i><\/td>\n Hay g\u1eb7p<\/span><\/i><\/td>\n \u00cdt g\u1eb7p<\/span><\/i><\/td>\n Hi\u1ebfm g\u1eb7p<\/span><\/i><\/td>\n R\u1ea5t hi\u1ebfm g\u1eb7p<\/span><\/i><\/td>\n Ch\u01b0a r\u00f5<\/span><\/i><\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n m\u00e1u v\u00e0 h\u1ec7 b\u1ea1ch huy\u1ebft<\/span><\/i><\/td>\n <\/td>\n <\/td>\n Gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u.<\/span><\/td>\n M\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, gi\u1ea3m to\u00e0n th\u1ec3 huy\u1ebft<\/span><\/p>\n
c\u1ea7u<\/span><\/td>\n
<\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n h\u1ec7 mi\u1ec5n d\u1ecbch<\/span><\/i><\/td>\n <\/td>\n <\/td>\n Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn nh\u01b0 s\u1ed1t, ph\u00f9 m\u1ea1ch v\u00e0 ph\u1ea3n \u1ee9ng\/s\u1ed1c d\u1ea1ng ph\u1ea3n v\u1ec7<\/span><\/td>\n <\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a v\u00e0 dinh d\u01b0\u1ee1ng<\/span><\/i><\/td>\n <\/td>\n Ph\u00f9 ngo\u1ea1i bi\u00ean.<\/span><\/td>\n Gi\u1ea3m natri m\u00e1u<\/span><\/td>\n <\/td>\n Gi\u1ea3m magnesi m\u00e1u; gi\u1ea3m magnesi<\/span><\/p>\n
m\u00e1u nghi\u00eam tr\u1ecdng c\u00f3 th\u1ec3 li\u00ean quan \u0111\u1ebfn<\/span><\/p>\n
gi\u1ea3m canxi m\u00e1u. Gi\u1ea3m magnesi m\u00e1u c\u0169ng c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn gi\u1ea3m kali m\u00e1u.<\/span><\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n<\/span><\/i><\/td>\n <\/td>\n M\u1ea5t ng\u1ee7<\/span><\/td>\n K\u00edch \u0111\u1ed9ng, l\u00fa l\u1eabn, tr\u1ea7m c\u1ea3m<\/span><\/td>\n N\u00f3ng n\u1ea3y, \u1ea3o gi\u00e1c<\/span><\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n h\u1ec7 th\u1ea7n kinh\u00a0<\/span><\/i><\/td>\n Nh\u1ee9c \u0111\u1ea7u<\/span><\/td>\n Cho\u00e1ng v\u00e1ng, d\u1ecb c\u1ea3m, ng\u1ee7 g\u00e0.<\/span><\/td>\n R\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c<\/span><\/td>\n <\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n m\u1eaft\u00a0<\/span><\/i><\/td>\n <\/td>\n Nh\u00ecn m\u1edd<\/span><\/td>\n <\/td>\n <\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n tai v\u00e0 tai trong<\/span><\/i><\/td>\n <\/td>\n Ch\u00f3ng m\u1eb7t<\/span><\/td>\n <\/td>\n <\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n h\u00f4 h\u1ea5p, l\u1ed3ng ng\u1ef1c v\u00e0 trung th\u1ea5t<\/span><\/i><\/td>\n <\/td>\n <\/td>\n Co th\u1eaft ph\u1ebf qu\u1ea3n<\/span><\/td>\n <\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a<\/span><\/i><\/td>\n \u0110au b\u1ee5ng, t\u00e1o b\u00f3n, ti\u00eau ch\u1ea3y, \u0111\u1ea7y b\u1ee5ng, bu\u1ed3n n\u00f4n\/n\u00f4n.<\/span><\/td>\n Kh\u00f4 mi\u1ec7ng<\/span><\/td>\n Vi\u00eam mi\u1ec7ng, nhi\u1ec5m Candida \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/span><\/td>\n <\/td>\n Vi\u00eam \u0111\u1ea1i tr\u00e0ng vi th\u1ec3<\/span><\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n gan m\u1eadt<\/span><\/i><\/td>\n <\/td>\n T\u0103ng enzym gan.<\/span><\/td>\n Vi\u00eam gan c\u00f3 ho\u1eb7c kh\u00f4ng v\u00e0ng da.<\/span><\/td>\n Suy gan, b\u1ec7nh n\u00e3o \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e3 c\u00f3 b\u1ec7nh gan<\/span><\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n da v\u00e0 m\u00f4 d\u01b0\u1edbi da<\/span><\/i><\/td>\n Ph\u1ea3n \u1ee9ng t\u1ea1i ch\u1ed7 ti\u00eam\/ti\u00eam truy\u1ec1n<\/span><\/td>\n Vi\u00eam da, ng\u1ee9a, n\u1ed5i m\u1eabn, m\u1ec1 \u0111ay.<\/span><\/td>\n H\u00f3i \u0111\u1ea7u, nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng<\/span><\/td>\n H\u1ed3ng ban \u0111a d\u1ea1ng, h\u1ed9i ch\u1ee9ng Stevens – Johnson, ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec da nhi\u1ec5m \u0111\u1ed9c (TEN)<\/span><\/td>\n Lupus ban \u0111\u1ecf b\u00e1n c\u1ea5p da.<\/span><\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n c\u01a1 x\u01b0\u01a1ng v\u00e0 m\u00f4 li\u00ean k\u1ebft<\/span><\/i><\/td>\n <\/td>\n G\u00e3y x\u01b0\u01a1ng h\u00f4ng, x\u01b0\u01a1ng c\u1ed5 tay ho\u1eb7c c\u1ed9t s\u1ed1ng<\/span><\/td>\n \u0110au kh\u1edbp, \u0111au c\u01a1<\/span><\/td>\n Y\u1ebfu c\u01a1<\/span><\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n th\u1eadn v\u00e0 ti\u1ebft ni\u1ec7u<\/span><\/i><\/td>\n <\/td>\n <\/td>\n <\/td>\n Vi\u00eam th\u1eadn k\u1ebd: \u0111\u00e3 c\u00f3 b\u00e1o c\u00e1o v\u1ec1 suy th\u1eadn \u0111i k\u00e8m tr\u00ean m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n.<\/span><\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n h\u1ec7 sinh s\u1ea3n v\u00e0 tuy\u1ebfn v\u00fa\u00a0<\/span><\/i><\/td>\n <\/td>\n <\/td>\n <\/td>\n N\u1eef h\u00f3a tuy\u1ebfn v\u00fa.<\/span><\/td>\n <\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n t\u1ed5ng qu\u00e1t v\u00e0 t\u1ea1i ch\u1ed7\u00a0<\/span><\/i><\/td>\n <\/td>\n <\/td>\n Kh\u00f3 ch\u1ecbu, t\u0103ng ti\u1ebft m\u1ed3 h\u00f4i.<\/span><\/td>\n <\/td>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Thu\u1ed1c<\/td>\n T\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n
C\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf protease<\/td>\n T\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m ho\u1eb7c t\u0103ng n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong huy\u1ebft thanh \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng chung v\u1edbi omeprazol v\u00e0 kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi c\u00e1c thu\u1ed1c n\u00e0y.<\/td>\n<\/tr>\n
Methotrexat<\/td>\n Khi d\u00f9ng c\u00f9ng v\u1edbi c\u00e1c PPI, t\u0103ng n\u1ed3ng \u0111\u1ed9 methotrexat \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n. Trong \u0111i\u1ec1u tr\u1ecb methotrexat li\u1ec1u cao, c\u00f3 th\u1ec3 c\u1ea7n ph\u1ea3i xem x\u00e9t ng\u01b0ng s\u1eed d\u1ee5ng t\u1ea1m th\u1eddi esomeprazol.<\/td>\n<\/tr>\n
Tacrolimus<\/td>\n S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi esomeprazol \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 tacrolimus trong huy\u1ebft thanh. C\u1ea7n t\u0103ng c\u01b0\u1eddng theo d\u00f5i n\u1ed3ng \u0111\u1ed9 tacrolimus c\u0169ng nh\u01b0 ch\u1ee9c n\u0103ng th\u1eadn (\u0111\u1ed9 thanh th\u1ea3i creatinin) v\u00e0 li\u1ec1u tacrolimus \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh n\u1ebfu c\u1ea7n.<\/td>\n<\/tr>\n
C\u00e1c thu\u1ed1c c\u00f3 s\u1ef1 h\u1ea5p thu ph\u1ee5 thu\u1ed9c PH<\/td>\n S\u1ef1 \u1ee9c ch\u1ebf acid d\u1ea1 d\u00e0y trong khi \u0111i\u1ec1u tr\u1ecb v\u1edbi esomeprazol v\u00e0 c\u00e1c PPI kh\u00e1c c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m ho\u1eb7c t\u0103ng s\u1ef1 h\u1ea5p thu c\u00e1c thu\u1ed1c c\u00f3 s\u1ef1 h\u1ea5p thu ph\u1ee5 thu\u1ed9c v\u00e0o PH d\u1ea1 d\u00e0y<\/td>\n<\/tr>\n
C\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a b\u1edfi CYP2C19<\/td>\n Esomeprazol \u1ee9c ch\u1ebf CYP2C19, enzym ch\u00ednh chuy\u1ec3n h\u00f3a esomeprazol. Do \u0111\u00f3, khi esomeprazol \u0111\u01b0\u1ee3c k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a b\u1edfi CYP2C19, nh\u01b0 diazepam, citalopram, imipramin, clomipramin, phenytoin,\u2026 n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 t\u0103ng l\u00ean v\u00e0 c\u1ea7n gi\u1ea3m li\u1ec1u d\u00f9ng.<\/td>\n<\/tr>\n
Diazepam<\/td>\n D\u00f9ng \u0111\u1ed3ng th\u1eddi esomeprazol 30 mg d\u1ea1ng u\u1ed1ng l\u00e0m gi\u1ea3m 45% \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a diazepam (m\u1ed9t c\u01a1 ch\u1ea5t c\u1ee7a CYP2C19).<\/td>\n<\/tr>\n
Phenytoin<\/td>\n D\u00f9ng \u0111\u1ed3ng th\u1eddi esomeprazol 40 mg d\u1ea1ng u\u1ed1ng v\u00e0 phenytoin l\u00e0m t\u0103ng 13% n\u1ed3ng \u0111\u1ed9 \u0111\u00e1y c\u1ee7a phenytoin trong huy\u1ebft t\u01b0\u01a1ng \u1edf b\u1ec7nh nh\u00e2n \u0111\u1ed9ng kinh. N\u00ean theo d\u00f5i<\/p>\n
n\u1ed3ng \u0111\u1ed9 phenytoin trong huy\u1ebft t\u01b0\u01a1ng khi b\u1eaft \u0111\u1ea7u hay ng\u01b0ng \u0111i\u1ec1u tr\u1ecb v\u1edbi esomeprazol<\/td>\n<\/tr>\n
Voriconazol<\/td>\n Omeprazol (40 mg, 1 l\u1ea7n\/ng\u00e0y) l\u00e0m t\u0103ng Cmax v\u00e0 AUC c\u1ee7a voriconazol (m\u1ed9t c\u01a1 ch\u1ea5t c\u1ee7a CYP2C19) l\u00ean t\u01b0\u01a1ng \u1ee9ng l\u00e0 15% v\u00e0 41%<\/td>\n<\/tr>\n
Cilostazol<\/td>\n Omeprazol c\u0169ng nh\u01b0 esomeprazol ho\u1ea1t \u0111\u1ed9ng nh\u01b0 c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf CYP2C19. Trong m\u1ed9t nghi\u00ean c\u1ee9u ch\u00e9o, omeprazol d\u00f9ng v\u1edbi li\u1ec1u 40 mg tr\u00ean c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng kh\u1ecfe m\u1ea1nh \u0111\u00e3 l\u00e0m t\u0103ng 18% Cmax v\u00e0 26% AUC c\u1ee7a cilostazol v\u00e0 l\u00e0m t\u0103ng t\u01b0\u01a1ng \u1ee9ng 29% Cmax v\u00e0 69% AUC c\u1ee7a m\u1ed9t trong c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh.<\/td>\n<\/tr>\n
Cisaprid<\/td>\n \u1ede nh\u1eefng ng\u01b0\u1eddi t\u00ecnh nguy\u1ec7n kh\u1ecfe m\u1ea1nh, khi d\u00f9ng chung 40 mg esomeprazol d\u1ea1ng u\u1ed1ng v\u00e0 cisaprid, di\u1ec7n t\u00edch d\u01b0\u1edbi \u0111\u01b0\u1eddng cong bi\u1ec3u di\u1ec5n n\u1ed3ng \u0111\u1ed9 cisaprid trong huy\u1ebft t\u01b0\u01a1ng theo th\u1eddi gian (AUC) t\u0103ng l\u00ean 32% v\u00e0 th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a cisaprid (t1\/2) k\u00e9o d\u00e0i th\u00eam 31% nh\u01b0ng n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh cisaprid trong huy\u1ebft t\u01b0\u01a1ng t\u0103ng l\u00ean kh\u00f4ng \u0111\u00e1ng k\u1ec3. Kho\u1ea3ng QTc h\u01a1i k\u00e9o d\u00e0i sau khi d\u00f9ng cisaprid ri\u00eang l\u1ebb, kh\u00f4ng b\u1ecb k\u00e9o d\u00e0i h\u01a1n n\u1eefa khi d\u00f9ng cisaprid ph\u1ed1i h\u1ee3p v\u1edbi esomeprazol.<\/td>\n<\/tr>\n
Warfarin<\/td>\n Khi d\u00f9ng \u0111\u1ed3ng th\u1eddi 40 mg esomeprazol d\u1ea1ng u\u1ed1ng \u1edf b\u1ec7nh nh\u00e2n \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1eb1ng warfarin trong m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111\u00e3 cho th\u1ea5y th\u1eddi gian \u0111\u00f4ng m\u00e1u \u1edf trong kho\u1ea3ng c\u00f3 th\u1ec3 ch\u1ea5p nh\u1eadn \u0111\u01b0\u1ee3c.<\/td>\n<\/tr>\n
Clopidogrel<\/td>\n C\u00e1c k\u1ebft qu\u1ea3 t\u1eeb c\u00e1c nghi\u00ean c\u1ee9u tr\u00ean c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng kh\u1ecfe m\u1ea1nh \u0111\u00e3 cho th\u1ea5y t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc (PK)\/d\u01b0\u1ee3c l\u1ef1c h\u1ecdc (PD) gi\u1eefa clopidogrel (li\u1ec1u n\u1ea1p 300mg\/li\u1ec1u duy tr\u00ec 75mg\/ng\u00e0y) v\u00e0 esomeprazol (40mg\/ng\u00e0y \u0111\u01b0\u1eddng u\u1ed1ng) d\u1eabn \u0111\u1ebfn gi\u1ea3m trung b\u00ecnh 40% s\u1ef1 ti\u1ebfp x\u00fac c\u1ee7a c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh c\u1ee7a clopidogrel v\u00e0 gi\u1ea3m trung b\u00ecnh 14% s\u1ef1 \u1ee9c ch\u1ebf t\u1ed1i \u0111a k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u (g\u00e2y b\u1edfi ADP)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n
Khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa n\u00ean h\u1ecfi \u00fd ki\u1ebfn c\u1ee7a b\u00e1c s\u0129 v\u1ec1 t\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 tr\u01b0\u1edbc khi d\u00f9ng thu\u1ed1c.<\/span><\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n
C\u00e1c tri\u1ec7u ch\u1ee9ng \u0111\u01b0\u1ee3c m\u00f4 t\u1ea3 c\u00f3 li\u00ean quan \u0111\u1ebfn li\u1ec1u u\u1ed1ng 280 mg l\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng ti\u00eau h\u00f3a v\u00e0 suy nh\u01b0\u1ee3c. C\u00e1c li\u1ec1u \u0111\u01a1n esomeprazol d\u1ea1ng u\u1ed1ng 80 mg v\u00e0 d\u1ea1ng d\u00f9ng t\u0129nh m\u1ea1ch 308<\/span><\/p>\n
mg esomeprazol trong su\u1ed1t 24 gi\u1edd kh\u00f4ng g\u00e2y t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n. Ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u. Esomeprazol g\u1eafn k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng v\u00e0 do \u0111\u00f3 kh\u00f4ng d\u1ec5 d\u00e0ng th\u1ea9m ph\u00e2n \u0111\u01b0\u1ee3c. Trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u n\u00ean \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 s\u1eed d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 t\u1ed5ng qu\u00e1t.<\/span><\/p>\n
Thu\u1ed1c Esogas Bidiphar gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n
Esogas 40mg gi\u00e1 bao nhi\u00eau<\/b> ? Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n
K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:\u00a0\u00a0<\/span><\/p>\n
Thu\u1ed1c Esotrax<\/span><\/a> l\u00e0 thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng v\u00e0 tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Esomeprazol v\u1edbi h\u00e0m l\u01b0\u1ee3ng 20mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Mepro Pharmaceuticals. Ltd-Unit 2-\u1ea4n \u0110\u1ed9. Hi\u1ec7n thu\u1ed1c \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 450.000 \u0111\u1ed3ng\/ h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<\/span><\/p>\n
Thu\u1ed1c Emerazol <\/span><\/a>l\u00e0 thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng h\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Esomeprazol pellets v\u1edbi h\u00e0m l\u01b0\u1ee3ng 20 mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m 3\/2 (F.T.PHARMA) \u2013 VI\u1ec6T NAM. Hi\u1ec7n thu\u1ed1c \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 82.000 \u0111\u1ed3ng\/ h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<\/span><\/p>\n
T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Esogas Bidiphar ?<\/span><\/h2>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
Esogas Bidiphar<\/b> v\u1edbi th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 esomeprazol gi\u00fap \u0111i\u1ec1u tr\u1ecb c\u00e1c t\u00ecnh tr\u1ea1ng vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y – t\u00e1 tr\u00e0ng, d\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb vi\u00eam lo\u00e9t do s\u1eed d\u1ee5ng nh\u00f3m Nsaids,…<\/p>\n
Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng d\u01b0\u1edbi d\u1ea1ng ti\u00eam n\u00ean d\u1ec5 d\u00e0ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sinh kh\u1ea3 d\u1ee5ng cao, d\u1ec5 h\u1ea5p thu v\u00e0 \u0111\u1ea1t \u0111\u01b0\u1ee3c hi\u1ec7u qu\u1ea3 mong mu\u1ed1n.<\/p>\n
Esogas Bidiphar \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c-TTBYT B\u00ecnh \u0110\u1ecbnh (Bidiphar), c\u00f3 c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t hi\u1ec7n \u0111\u1ea1i, ti\u00ean ti\u1ebfn, \u0111\u1ea1t chu\u1ea9n GMP n\u00ean s\u1ea3n ph\u1ea9m \u0111\u1ea1t ch\u1ea5t l\u01b0\u1ee3ng cao, uy t\u00edn.<\/td>\n
Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ra nh\u1eefng t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 t\u01b0\u01a1ng t\u00e1c n\u00ean c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng.<\/p>\n
Thu\u1ed1c khuy\u1ebfn c\u00e1o kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 cho con b\u00fa n\u1ebfu kh\u00f4ng c\u00f3 s\u1ef1 \u0111\u1ed3ng \u00fd c\u1ee7a b\u00e1c s\u0129.<\/p>\n
V\u00ec d\u00f9ng thu\u1ed1c b\u1eb1ng \u0111\u01b0\u1eddng ti\u00eam n\u00ean ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng t\u1ef1 s\u1eed d\u1ee5ng \u0111\u01b0\u1ee3c v\u00e0 kh\u1ea3 n\u0103ng s\u1ed1c ph\u1ea3n v\u1ec7 cao c\u1ea7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi chuy\u00ean gia y t\u1ebf.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n
\n
\u0110\u01b0\u1ee3c vi\u1ebft b\u1edfi chuy\u00ean gia c\u1ee7a Drugs.com. (Th\u1eddi gian c\u1eadp nh\u1eadt l\u1ea7n cu\u1ed1i v\u00e0o ng\u00e0y 13 th\u00e1ng 6 n\u0103m 2023). <\/span>Esomeprazole (Intravenous)<\/span><\/i>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 28 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <\/span>https:\/\/www.drugs.com\/cons\/esomeprazole-intravenous.html<\/span><\/a>\u00a0<\/span><\/li>\n
T\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c ti\u00eam Esogas Bidiphar, T\u1ea1i \u0111\u00e2y<\/a>.<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
Esogas Bidiphar v\u1edbi th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 esomeprazol gi\u00fap \u0111i\u1ec1u tr\u1ecb c\u00e1c t\u00ecnh tr\u1ea1ng vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y – t\u00e1 tr\u00e0ng, d\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb vi\u00eam lo\u00e9t do s\u1eed d\u1ee5ng nh\u00f3m Nsaids,…<\/p>\n","protected":false},"author":490,"featured_media":53074,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-53068","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/53068","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=53068"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/53074"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=53068"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=53068"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=53068"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}