﻿{"id":51510,"date":"2023-10-26T15:11:28","date_gmt":"2023-10-26T08:11:28","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=51510"},"modified":"2025-07-24T13:59:58","modified_gmt":"2025-07-24T06:59:58","slug":"thuoc-neso-500mg-20mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-neso-500mg-20mg\/","title":{"rendered":"Neso 500mg\/20mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/thuoc-neso-500mg-20mg\/\">Neso 500mg\/20mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Aristopharma., Ltd &#8211; B\u0103ng La \u0110\u00e9t, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-22492-20<\/b><\/p>\n<h2><span style=\"font-weight: 400\">Neso 500mg\/20mg l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Neso 500mg\/20mg c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<p><span style=\"font-weight: 400\">M\u1ed7i vi\u00ean n\u00e9n bao tan trong ru\u1ed9t ch\u1ee9a <\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400\">Napoleon BP 500mg. <\/span><\/li>\n<li><span style=\"font-weight: 400\">Esomeprazole USP t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi 20mg Esomeprazole. <\/span><\/li>\n<li><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c : Pregelatinised starch, Povidone (K30), Crospovidone, Mannitol, Anhydrous Sodium Carbonate, Hydroxypropyl Methylcellulose, Sodium Lauryl Sylphate, Sodium Starch Glycolate, Purified Talc, Magnesium Stearate, Kollicoat MAE 30DP, Lemon Yellow color powder, Titanium dioxide.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: VN-22492-20<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: M\u1ed7i h\u1ed9p ch\u1ee9a 10 v\u1ec9 x 4 vi\u00ean n\u00ean.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: Bangladesh<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Neso c\u00f3 t\u00e1c d\u1ee5ng g\u00ec ?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Naproxen l\u00e0 m\u1ed9t NSAID v\u1edbi t\u00e1c \u0111\u1ed9ng gi\u1ea3m \u0111au v\u00e0 h\u1ea1 s\u1ed1t. C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng c\u1ee7a Naproxen gi\u1ed1ng nh\u01b0 c\u00e1c NSAID kh\u00e1c, li\u00ean quan \u0111\u1ebfn s\u1ef1 \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p prostaglandin.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Esomeprazole l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf b\u01a1m proton, \u1ee9c ch\u1ebf s\u1ef1 ti\u1ebft acid d\u1ea1 d\u00e0y b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a b\u01a1m H+\/K+ ATPase trong t\u1ebf b\u00e0o th\u00e0nh d\u1ea1 d\u00e0y- b\u01b0\u1edbc cu\u1ed1i c\u00f9ng trong qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t acid d\u1ea1 d\u00e0y, t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m acid d\u1ea1 d\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Esomeprazole d\u1ef1 ph\u00f2ng v\u1ebft lo\u00e9t c\u00f3 th\u1ec3 g\u00e2y ra do d\u00f9ng Naproxen ho\u1eb7c c\u00e1c NSAID kh\u00e1c<\/span><\/p>\n<p><span style=\"font-weight: 400\">T\u00e1c \u0111\u1ed9ng c\u1ee7a NESO l\u00ean pH d\u1ea1 d\u00e0y:<\/span><\/p>\n<p><span style=\"font-weight: 400\">T\u00e1c \u0111\u1ed9ng c\u1ee7a NESO tr\u00ean pH d\u1ea1 d\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh \u1edf 25 t\u1ec9nh nguy\u1ec7n vi\u00ean kh\u1ecfe m\u1ea1nh trong m\u1ed9t nghi\u00ean c\u1ee9u. Ba k\u1ebft h\u1ee3p NESO (naproxen 500 mg k\u1ebft h\u1ee3p v\u1edbi ho\u1eb7c esomeprazole 10, 20, 30 ho\u1eb7c mg) \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng 2 l\u1ea7n m\u1ed7i ng\u00e0y trong 9 ng\u00e0y.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<table style=\"width: 98.1498%;height: 844px\">\n<tbody>\n<tr style=\"height: 10px\">\n<td style=\"width: 14.55%;height: 10px\"><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 44.9084%;height: 10px\"><span style=\"font-weight: 400\">Naproxen<\/span><\/td>\n<td style=\"width: 442.193%;height: 10px\"><span style=\"font-weight: 400\">Esomeprazole<\/span><\/td>\n<\/tr>\n<tr style=\"height: 192px\">\n<td style=\"width: 14.55%;height: 192px\"><span style=\"font-weight: 400\">H\u1ea5p thu<\/span><\/td>\n<td style=\"width: 44.9084%;height: 192px\"><span style=\"font-weight: 400\">Naproxen h\u1ea5p thu nhanh v\u00e0 ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, v\u1edbi sinh kh\u1ea3 d\u1ee5ng in vivo 95%.<\/span><\/p>\n<p><span style=\"font-weight: 400\">N\u1ed3ng \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh c\u1ee7a Naproxen \u0111\u1ea1t \u0111\u01b0\u1ee3c trong 4 \u0111\u1ebfn 5 ng\u00e0y.<\/span><\/td>\n<td style=\"width: 442.193%;height: 192px\"><span style=\"font-weight: 400\">Sau khi s\u1eed d\u1ee5ng NESO 2 l\u1ea7n m\u1ed7i ng\u00e0y, esomeprazole \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh v\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau th\u1eddi gian trung b\u00ecnh 0,5-0,75 gi\u1edd sau c\u1ea3 li\u1ec1u bu\u1ed5i s\u00e1ng v\u00e0 li\u1ec1u bu\u1ed5i t\u1ed1i c\u1ee7a ng\u00e0y d\u00f9ng thu\u1ed1c \u0111\u1ea7u ti\u00ean v\u00e0 \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 156px\">\n<td style=\"width: 14.55%;height: 156px\"><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1<\/span><\/td>\n<td style=\"width: 44.9084%;height: 156px\"><span style=\"font-weight: 400\">Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a Naproxen 0,16 L\/kg. \u1ede li\u1ec1u \u0111i\u1ec1u tr\u1ecb h\u01a1n 99% naproxen g\u1eafn k\u1ebft v\u1edbi albumin huy\u1ebft t\u01b0\u01a1ng. Naproxen \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong s\u1eefa c\u1ee7a ph\u1ee5 n\u1eef cho con b\u00fa \u1edf n\u1ed3ng \u0111\u1ed9 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng kho\u1ea3ng 1% n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng<\/span><\/td>\n<td style=\"width: 442.193%;height: 156px\"><span style=\"font-weight: 400\">Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a esomeprazole 0,22 L\/kg. T\u1ec9 l\u1ec7 g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng l\u00e0 97%<\/span><\/td>\n<\/tr>\n<tr style=\"height: 129px\">\n<td style=\"width: 14.55%;height: 129px\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a<\/span><\/td>\n<td style=\"width: 44.9084%;height: 129px\"><span style=\"font-weight: 400\">30% Naproxen \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan b\u1edfi h\u1ec7 th\u1ed1ng cytochrom P450, ch\u1ee7 y\u1ebfu l\u00e0 CYP2C9, t\u1ea1o th\u00e0nh 6,0 desmethyt. C\u1ea3 naproxen v\u00e0 6,0 desmethyl naproxen ti\u1ebfp t\u1ee5c b\u1ecb chuy\u1ec3n h\u00f3a th\u00e0nh c\u00e1c li\u00ean h\u1ee3p acylglucuronic.<\/span><\/td>\n<td style=\"width: 442.193%;height: 129px\"><span style=\"font-weight: 400\">Esomeprazole \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ho\u00e0n to\u00e0n b\u1edfi h\u1ec7 th\u1ed1ng cytochrom. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a esomeprazole kh\u00f4ng c\u00f3 t\u00e1c \u0111\u1ed9ng tr\u00ean s\u1ef1 ti\u1ebft acid d\u1ea1 d\u00e0y.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 357px\">\n<td style=\"width: 14.55%;height: 357px\"><span style=\"font-weight: 400\">Th\u1ea3i tr\u1eeb<\/span><\/td>\n<td style=\"width: 44.9084%;height: 357px\"><span style=\"font-weight: 400\">Sau khi s\u1eed d\u1ee5ng NESO 2 l\u1ea7n m\u1ed7i ng\u00e0y, T1\/2 l\u1ea7n l\u01b0\u1ee3t 9 gi\u1edd v\u00e0 15 gi\u1edd sau li\u1ec1u bu\u1ed5i s\u00e1ng v\u00e0 bu\u1ed5i t\u1ed1i, kh\u00f4ng c\u00f3 thay \u0111\u1ed5i khi s\u1eed d\u1ee5ng li\u1ec1u l\u1eb7p \u0111i l\u1eb7p l\u1ea1i.<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u0110\u1ed9 thanh th\u00e1i c\u1ee7a naproxen 0,13 ml\/ph\u00fat kg. Kho\u1ea3ng 95% naproxen \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft trong n\u01b0\u1edbc ti\u1ec3u, d\u01b0\u1edbi d\u1ea1ng naproxen(&lt;1%), 6,0 desmethyl naproxen (&lt;1%) ho\u1eb7c c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00e1c (66-92%). L\u01b0\u1ee3ng nh\u1ecf (&lt;3%) li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft trong ph\u00e2n. \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n suy th\u1eadn, c\u00f3 th\u1ec3 c\u00f3 s\u1ef1 t\u00edch l\u0169y c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a.<\/span><\/td>\n<td style=\"width: 442.193%;height: 357px\"><span style=\"font-weight: 400\">Sau khi s\u1eed d\u1ee5ng NESO 2 l\u1ea7n m\u1ed7i ng\u00e0y, T1\/2 c\u1ee7a esomeprazole kho\u1ea3ng 1 gi\u1edd sau li\u1ec1u bu\u1ed5i s\u00e1ng v\u00e0 bu\u1ed5i t\u1ed1i c\u1ee7a ng\u00e0y 1, T1\/2 l\u00e2u h\u01a1n(kho\u1ea3ng 1,2-1,5 gi\u1edd khi \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh).<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thanh th\u00e1i huy\u1ebft t\u01b0\u01a1ng c\u1ee7a esomeprazole l\u00e0 kho\u1ea3ng 17 L\/ gi\u1edd sau li\u1ec1u \u0111\u1ea7u ti\u00ean v\u00e0 kho\u1ea3ng 9 L\/gi\u1edd sau khi d\u00f9ng li\u1ec1u l\u1eb7p l\u1ea1i.<\/span><\/p>\n<p><span style=\"font-weight: 400\">G\u1ea7n 80% li\u1ec1u u\u1ed1ng esomeprazole \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a qua n\u01b0\u1edbc ti\u1ec3u, ph\u1ea7n c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft trong ph\u00e2n. \u00cdt h\u01a1n 1% d\u1ea1ng nguy\u00ean v\u1eb9n \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Neso 500mg\/20mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Gi\u1ea3m c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng c\u1ee7a vi\u00eam x\u01b0\u01a1ng kh\u1edbp, vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p, vi\u00eam c\u1ed9t s\u1ed1ng c\u1ee9ng kh\u1edbp<\/span><\/p>\n<p><span style=\"font-weight: 400\">L\u00e0m gi\u1ea3m nguy c\u01a1 ti\u1ebfn tri\u1ec3n vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y do s\u1eed d\u1ee5ng NSAID. Esomeprazole l\u00e0m gi\u1ea3m nguy c\u01a1 lo\u00e9t v\u00e0 c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 d\u1ea1 d\u00e0y ti\u1ebfn tri\u1ec3n \u1edf b\u1ec7nh nh\u00e2n c\u1ea7n \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Naproxen hay c\u00e1c NSAID kh\u00e1c. T\u00f9y thu\u1ed9c v\u00e0o v\u1ecb tr\u00ed c\u1ee7a v\u1ebft lo\u00e9t n\u00f3 \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 lo\u00e9t d\u1ea1 d\u00e0y ho\u1eb7c lo\u00e9t t\u00e1 tr\u00e0ng. Nguy\u00ean nh\u00e2n c\u1ee7a v\u1ebft lo\u00e9t c\u00f3 th\u1ec3 l\u00e0 do acid trong d\u1ea1 d\u00e2y qu\u00e1 cao.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Neso 500mg\/20mg<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng l\u00e0 1 vi\u00ean x 2 l\u1ea7n m\u1ed7i ng\u00e0y Neso 500mg\/20mg (Naproxen 500mg v\u00e0 Esomeprazole 20mg).<\/span><\/p>\n<p><span style=\"font-weight: 400\">D\u00f9ng tr\u01b0\u1edbc b\u1eefa \u0103n \u00edt nh\u1ea5t 30 ph\u00fat.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Neso 500mg\/20mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<ul>\n<li><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n qu\u00e1 m\u1eabn v\u1edbi Naproxen, Esomeprazole Magnesium, ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n t\u00e1 d\u01b0\u1ee3c n\u00e0o.<\/span><\/li>\n<li><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed b\u1ecb hen suy\u1ec5n, n\u1ed5i m\u1ec1 \u0111ay ho\u1eb7c c\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng sau khi s\u1eed d\u1ee5ng aspirin ho\u1eb7c c\u00e1c NSAID kh\u00e1c<\/span><\/li>\n<li><span style=\"font-weight: 400\">\u0110i\u1ec1u tr\u1ecb \u0111au trong c\u00e1c ph\u1eabu thu\u1eadt b\u1eafc c\u1ea7u \u0111\u1ed9ng m\u1ea1ch v\u00e0nh, \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n trong giai \u0111o\u1ea1n cu\u1ed1i c\u1ee7a thai k\u1ef3.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Neso 500mg\/20mg<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Tr\u00e1nh s\u1eed d\u1ee5ng NESO \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c NSAID kh\u00e1c, bao g\u1ed3m c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc COX-2. C\u00f3 th\u1ec3 s\u1eed d\u1ee5ng NESO v\u1edbi aspirin li\u1ec1u th\u1ea5p.<\/span><\/p>\n<p><span style=\"font-weight: 400\">C\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 l\u00e0m t\u0103ng c\u00e1c bi\u1ebfn ch\u1ee9ng d\u1ea1 d\u00e0y-ru\u1ed9t do NSAID bao g\u1ed3m tu\u1ed5i cao, s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng, corticosteroid, NSAID kh\u00e1c bao g\u1ed3m c\u1ea3 axit acety; salicylic li\u1ec1u th\u1ea5p, b\u1ec7nh tim m\u1ea1ch, ti\u1ec1n s\u1eed lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n \u1edf t\u00ecnh tr\u1ea1ng sau, maproxen ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng khi c\u00e2n nh\u1eafc k\u0129 gi\u1eefa l\u1ee3i \u00edch v\u00e0 nguy c\u01a1.<\/span><\/p>\n<p><span style=\"font-weight: 400\">-B\u1ec7nh lupus h\u1ec7 th\u1ed1ng v\u00e0 b\u1ec7nh m\u00f4 li\u00ean k\u1ebft h\u1ed7n h\u1ee3p.<\/span><\/p>\n<p><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb l\u00e2u d\u00e0i (\u0111\u1eb7c bi\u1ec7t l\u00e0 nh\u1eefng ng\u01b0\u1eddi \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb h\u01a1n 1 n\u0103m) n\u00ean \u0111\u01b0\u1ee3c gi\u1ea3m s\u00e1t th\u01b0\u1eddng xuy\u00ean.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Ng\u01b0\u1eddi l\u1edbn tu\u1ed5i.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Naproxen. Ng\u01b0\u1eddi cao tu\u1ed5i t\u0103ng t\u1ea7n su\u1ea5t c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i, \u0111\u1eb7c bi\u1ec7t l\u00e0 d\u1ea1 d\u00e0y-ru\u1ed9t, xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a, c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Esomepraole c\u1ee7a NESO c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u1ec9 l\u1ec7 lo\u00e9t \u1edf ng\u01b0\u1eddi gi\u00e0.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/h3>\n<p><span style=\"font-weight: 400\">C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o v\u1edbi s\u1ef1 k\u1ebft h\u1ee3p n\u00e0y bao g\u1ed3m r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a nh\u01b0 kh\u00f3 ti\u00eau, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, \u0111\u1ea7y h\u01a1i, \u0111au b\u1ee5ng. Th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n<p><span style=\"font-weight: 400\">M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u \u0111\u00e3 cho th\u1ea5y kh\u00f4ng c\u00f3 s\u1ef1 t\u01b0\u01a1ng t\u00e1c gi\u1eefa hai th\u00e0nh ph\u1ea7n Naproxen v\u00e0 Esomeprazole.<\/span><\/p>\n<p><span style=\"font-weight: 400\">NSAID c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Probenecid l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 anion Naproxen trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 t\u0103ng \u0111\u00e1ng k\u1ec3 T1\/2 huy\u1ebft t\u01b0\u01a1ng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng, diazepam, phenytoin ho\u1eb7c quinidine h\u1ea7u nh\u01b0 kh\u00f4ng \u0111\u1ec3 thay \u0111\u1ed5i \u0111\u1eb7c t\u00ednh d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a Esomeprazole.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">S\u1eed d\u1ee5ng trong th\u1eddi k\u1ef3 mang thai: Naproxen &amp; Esomeprazole \u0111\u1ec1u x\u1ebfp lo\u1ea1i B trong s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai. S\u1ef1 k\u1ebft h\u1ee3p n\u00e0y n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong th\u1eddi k\u1ef3 mang thai ch\u1ec9 khi l\u1ee3i \u00edch ti\u1ec1m n\u0103ng l\u1edbn h\u01a1n r\u1ee7i ro cho thai nhi.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">S\u1eed d\u1ee5ng cho b\u00e0 m\u1eb9 \u0111ang cho con b\u00fa: Naproxen &amp; Esomeprazole c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9, c\u00e2n nh\u1eafc quy\u1ebft \u0111\u1ecbnh xem c\u00f3 n\u00ean ng\u1eebng cho con b\u00fa ho\u1eb7c ng\u1eebng thu\u1ed1c, c\u00f3 t\u00ednh \u0111\u1ebfn t\u1ea7m quan tr\u1ecdng c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eb9.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Ch\u01b0a c\u00f3 ghi nh\u1eadn c\u00e1c tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u s\u1eed d\u1ee5ng<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Neso gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\"><strong>Neso gi\u00e1 bao nhi\u00eau<\/strong>? Thu\u1ed1c Neso 500mg\/20mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:\u00a0\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"><a href=\"https:\/\/vnras.com\/drug\/thuoc-khop-phong-dan\/\">Kh\u1edbp Phong Dan<\/a> \u0111\u1ec3 gi\u1ea3m c\u00e1c ch\u1ee9ng \u0111au nh\u1ee9c c\u00e1c kh\u1edbp, \u0111au l\u01b0ng, \u0111au c\u1ed9t s\u1ed1ng, \u0111au d\u00e2y th\u1ea7n kinh t\u1ecda, ch\u1ee9a th\u00e0nh ph\u1ea7n l\u00e0 c\u00e1c th\u1ea3o d\u01b0\u1ee3c qu\u00fd, \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 180,000\u20ab\/ h\u1ed9p.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"><a href=\"https:\/\/vnras.com\/drug\/an-khop-ba-ngo\/\">An Kh\u1edbp B\u00e0 Ng\u1ecd<\/a> c\u00f3 t\u00e1c d\u1ee5ng trong vi\u1ec7c h\u1ed7 tr\u1ee3 l\u01b0u th\u00f4ng kh\u00ed huy\u1ebft, th\u00f4ng c\u00e1c \u0111\u01b0\u1eddng kinh l\u1ea1c, l\u00e0m gi\u1ea3m b\u1edbt c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a c\u00e1c b\u1ec7nh l\u00fd x\u01b0\u01a1ng kh\u1edbp nh\u01b0 gi\u1ea3m vi\u00eam kh\u1edbp, gi\u1ea3m s\u01b0ng, h\u1ea1n ch\u1ebf \u0111au\u2026.th\u00e0nh ph\u1ea7n ch\u00ednh g\u1ed3m c\u00f3: B\u1ed3 c\u00f4ng anh, Hy thi\u00eam, V\u01b0\u01a1ng t\u00f4n, Th\u01b0\u01a1ng nh\u0129 t\u1eed\u2026. S\u1ea3n ph\u1ea9m An Kh\u1edbp B\u00e0 Ng\u1ecd gi\u00e1 625.000 \u0111\u1ed3ng 1 h\u1ed9p.\u00a0<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Neso 500mg \/ 20mg?<\/span><\/h2>\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 58.2278%\"><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 40.0844%\"><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 58.2278%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Neso 500mg \/ 20mg ch\u1ee9a <\/span><b>Naproxen 500<\/b><span style=\"font-weight: 400\"> mg, Naproxen \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh g\u00fat c\u1ea5p t\u00ednh, vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp, vi\u00eam bao ho\u1ea1t d\u1ecbch, vi\u00eam kh\u1edbp v\u00f4 c\u0103n \u1edf tr\u1ebb v\u1ecb th\u00e0nh ni\u00ean, vi\u00eam x\u01b0\u01a1ng kh\u1edbp, vi\u00eam g\u00e2n, vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p, \u0111au v\u00e0 \u0111au b\u1ee5ng kinh nguy\u00ean ph\u00e1t.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Esomeprazole \u0111\u00e3 \u0111\u01b0\u1ee3c FDA ph\u00ea chu\u1ea9n ghi nh\u00e3n \u0111\u1ec3 s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n c\u00f3 tri\u1ec7u ch\u1ee9ng (GERD), bao g\u1ed3m ch\u1eefa l\u00e0nh v\u00e0 duy tr\u00ec vi\u1ec7c ch\u1eefa l\u00e0nh b\u1ec7nh vi\u00eam th\u1ef1c qu\u1ea3n \u0103n m\u00f2n v\u00e0 l\u00e0 m\u1ed9t ph\u1ea7n c\u1ee7a ph\u00e1c \u0111\u1ed3 ba thu\u1ed1c \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m Helicobocter pylori.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf vi\u00ean n\u00e9n n\u00ean d\u1ec5 d\u00e0ng b\u1ea3o qu\u1ea3n, ti\u1ec7n d\u1ee5ng, d\u1ec5 s\u1eed d\u1ee5ng.\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 40.0844%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4ng n\u00ean d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea7n ch\u00fa \u00fd v\u00ec thu\u1ed1c c\u00f3 nhi\u1ec1u t\u01b0\u01a1ng t\u00e1c.\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i b\u1ea3n PDF <a href=\"https:\/\/vnras.com\/drug\/?attachment_id=51529\">t\u1ea1i \u0111\u00e2y<\/a><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3 Joseph C. Brutzkus v\u00e0 c\u1ed9ng s\u1ef1 (\u0110\u0103ng ng\u00e0y 4 th\u00e1ng 8 n\u0103m 2023), <\/span><i><span style=\"font-weight: 400\">Naproxen<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 9 n\u0103m 2023 t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30247840\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30247840\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3 Thomas J Johnson, Dennis D Hedge (\u0110\u0103ng ng\u00e0y<\/span><span style=\"font-weight: 400\">\u00a015 th\u00e1ng 7<\/span><span style=\"font-weight: 400\"> n\u0103m <\/span><span style=\"font-weight: 400\">2002<\/span><span style=\"font-weight: 400\">), <\/span><i><span style=\"font-weight: 400\">Esomeprazole: a clinical review<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 9 n\u0103m 2023 t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12132559\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/12132559\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Neso 500mg\/20mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Aristopharma., Ltd &#8211; B\u0103ng La \u0110\u00e9t, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-22492-20 Neso 500mg\/20mg l\u00e0 thu\u1ed1c g\u00ec? Th\u00e0nh ph\u1ea7n Thu\u1ed1c Neso 500mg\/20mg c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: M\u1ed7i [&#8230;]\n","protected":false},"author":490,"featured_media":51535,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-51510","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/51510","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=51510"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/51535"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=51510"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=51510"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=51510"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}