{"id":50744,"date":"2023-10-25T15:15:51","date_gmt":"2023-10-25T08:15:51","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=50744"},"modified":"2025-07-24T14:00:03","modified_gmt":"2025-07-24T07:00:03","slug":"sunirovel-150","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/sunirovel-150\/","title":{"rendered":"Sunirovel 150"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Sunirovel 150<\/a> d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Sun Pharmaceutical Industries Ltd., c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-16912-13.<\/b><\/p>\n

Thu\u1ed1c Sunirovel 150 l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n

Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n

Thu\u1ed1c Sunirovel 150 <\/b>c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n

Irbesartan USP 150mg.<\/span><\/p>\n

T\u00e1 d\u01b0\u1ee3c: Povidone, Tinh b\u1ed9t b\u1eafp BP, N\u01b0\u1edbc tinh khi\u1ebft BP, Poloxamer (188) NF,\u2026<\/span><\/p>\n

D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n.<\/span><\/p>\n

Tr\u00ecnh b\u00e0y<\/span><\/h3>\n

S\u0110K: VN-16912-13.<\/span><\/p>\n

Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 5 v\u1ec9 x 10 vi\u00ean.<\/span><\/p>\n

Xu\u1ea5t x\u1ee9: C\u00f4ng ty Sun Pharmaceutical Industries Ltd.<\/span><\/p>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Sunirovel 150<\/span><\/h2>\n

\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c l\u1ef1c h\u1ecdc<\/span><\/h3>\n

Irbesartan l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 angiotensin II (ph\u00e2n nh\u00f3m AT1), c\u00f3 th\u1ec3 \u1ee9c ch\u1ebf s\u1ef1 chuy\u1ec3n \u0111\u1ed5i angiotensin I th\u00e0nh angiotensin II. N\u00f3 c\u00f3 th\u1ec3 \u0111\u1ed1i kh\u00e1ng \u0111\u1eb7c bi\u1ec7t v\u1edbi th\u1ee5 th\u1ec3 AT1, s\u1ef1 co m\u1ea1ch v\u00e0 gi\u1ea3i ph\u00f3ng aldosterone b\u1ecb \u1ee9c ch\u1ebf b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n c\u00f3 ch\u1ecdn l\u1ecdc s\u1ef1 li\u00ean k\u1ebft c\u1ee7a angiotensin II v\u1edbi th\u1ee5 th\u1ec3 AT1, d\u1eabn \u0111\u1ebfn t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p v\u00e0 l\u00e0 lo\u1ea1i thu\u1ed1c th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p c\u1ea7n thi\u1ebft. C\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng cho th\u1ea5y Irbesartan \u1ed5n \u0111\u1ecbnh trong vi\u1ec7c gi\u1ea3m huy\u1ebft \u00e1p v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 th\u1ea5p. Trong c\u00e1c nghi\u00ean c\u1ee9u d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc, hi\u1ec7u qu\u1ea3 v\u00e0 li\u1ec1u l\u01b0\u1ee3ng cho th\u1ea5y m\u1ed1i t\u01b0\u01a1ng quan tuy\u1ebfn t\u00ednh \u0111\u00e1ng k\u1ec3 trong kho\u1ea3ng 10\u2013600mg, v\u1edbi t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p \u1ed5n \u0111\u1ecbnh v\u00e0 k\u00e9o d\u00e0i v\u00e0 gi\u1ea3m huy\u1ebft \u00e1p v\u00e0o ban \u0111\u00eam m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3 \u0111\u1ec3 kh\u00f4i ph\u1ee5c nh\u1ecbp sinh h\u1ecdc b\u00ecnh th\u01b0\u1eddng c\u1ee7a huy\u1ebft \u00e1p. Irbesartan c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng m\u1ed9t m\u00ecnh nh\u01b0ng c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng c\u00f9ng v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p kh\u00e1c<\/span><\/p>\n

\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n

H\u1ea5p thu: Nhanh. Irbesartan c\u00f3 sinh kh\u1ea3 d\u1ee5ng 60-80%. Sau 1,5-2 gi\u1edd, Irbesartan \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 cao nh\u1ea5t.<\/span><\/p>\n

Ph\u00e2n b\u1ed1: Kho\u1ea3ng 90% Irbesartan g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. V\u1edbi c\u00e1 t\u1ebf b\u00e0o m\u00e1u, Irbesartan g\u1eafn kh\u00f4ng \u0111\u00e1ng k\u1ec3. Irbesartan c\u00f3 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 53-93 l\u00edt. Irbesartan \u0111\u00e1nh d\u1ea5u ph\u00f3ng x\u1ea1 \u00edt v\u00e0o \u0111\u01b0\u1ee3c nhau thai, m\u00e1u n\u00e3o.<\/span><\/p>\n

Chuy\u1ec3n h\u00f3a: Th\u00f4ng qua qu\u00e1 tr\u00ecnh oxy h\u00f3a l\u00e0 li\u00ean h\u1ee3p c\u00f9ng Glucuronide. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a l\u00e0 \u1edf d\u1ea1ng li\u00ean h\u1ee3p Glucuronide v\u00e0 Irbesartan.<\/span><\/p>\n

Th\u1ea3i tr\u1eeb: \u0110\u1ed9 thanh th\u1ea3i c\u1ee7a Irbesartan l\u00e0 157-176 v\u00e0 3-3,5ml\/ph\u00fat \u1edf huy\u1ebft t\u01b0\u01a1ng v\u00e0 th\u1eadn. Irbesartan \u0111\u00e0o th\u1ea3i \u1edf th\u1eadn, m\u1eadt.1\/5 ho\u1ea1t t\u00ednh ph\u00f3ng x\u1ea1 xu\u1ea5t hi\u1ec7n \u1edf ph\u00e2n, n\u01b0\u1edbc ti\u1ec3u.<\/span><\/p>\n

Thu\u1ed1c huy\u1ebft \u00e1p Sunirovel 150 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n

T\u0103ng huy\u1ebft \u00e1p.<\/span><\/p>\n

C\u00f3 th\u1ec3 d\u00f9ng \u0111\u01a1n l\u1ebb ho\u1eb7c ph\u1ed1i h\u1ee3p.<\/span><\/p>\n

Ch\u1ed1ng t\u0103ng huy\u1ebft \u00e1p \u1edf ng\u01b0\u1eddi cao huy\u1ebft \u00e1p m\u1eafc ti\u1ec3u \u0111\u01b0\u1eddng type II.<\/span><\/p>\n

Li\u1ec1u d\u00f9ng v\u00e0 C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Sunirovel 150<\/span><\/h2>\n

Ban \u0111\u1ea7u: 1 vi\u00ean\/ng\u00e0y.<\/span><\/p>\n

C\u00f3 th\u1ec3 d\u00f9ng 2 vi\u00ean\/ng\u00e0y khi c\u1ea7n h\u1ea1 huy\u1ebft \u00e1p th\u00eam.<\/span><\/p>\n

N\u1ebfu huy\u1ebft \u00e1p kh\u00f4ng gi\u1ea3m c\u00f3 th\u1ec3 d\u00f9ng th\u00eam m\u1ed9t li\u1ec1u thu\u1ed1c l\u1ee3i ti\u1ec3u li\u1ec1u th\u1ea5p.<\/span><\/p>\n

V\u1edbi li\u1ec1u 2 vi\u00ean\/ng\u00e0y kh\u00f4ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb \u0111\u1ee7 th\u00ec vi\u1ec7c t\u0103ng th\u00eam d\u00f9ng 2 l\u1ea7n\/ng\u00e0y hay th\u00eam li\u1ec1u cao h\u01a1n c\u0169ng kh\u00f4ng th\u1ea5y hi\u1ec7u qu\u1ea3.<\/span><\/p>\n

Ng\u01b0\u1eddi gi\u1ea3m th\u1ec3 t\u00edch m\u00e1u, suy ki\u1ec7t mu\u1ed1i: N\u1eeda vi\u00ean\/ng\u00e0y.<\/span><\/p>\n

Thu\u1ed1c u\u1ed1ng v\u1edbi n\u01b0\u1edbc.<\/span><\/p>\n

U\u1ed1ng trong\/c\u00e1ch b\u1eefa \u0103n \u0111\u1ec1u \u0111\u01b0\u1ee3c.<\/span><\/p>\n

Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Sunirovel 150 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n

Ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi thu\u1ed1c.<\/span><\/p>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Sunirovel 150<\/span><\/h2>\n

Th\u1eadn tr\u1ecdng<\/span><\/h3>\n

Ng\u01b0\u1eddi cao huy\u1ebft \u00e1p kh\u00f4ng bi\u1ebfn ch\u1ee9ng khi u\u1ed1ng thu\u1ed1c r\u1ea5t hi\u1ebfm khi g\u00e2y h\u1ea1 huy\u1ebft \u00e1p qu\u00e1 m\u1ee9c.<\/span><\/p>\n

Ng\u01b0\u1eddi m\u1ea5t mu\u1ed1i, gi\u1ea3m th\u1ec3 t\u00edch n\u1ed9i m\u1ea1ch ban \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 b\u1ecb h\u1ea1 huy\u1ebft \u00e1p tri\u1ec7u ch\u1ee9ng. Ch\u00ednh v\u00ec th\u1ebf n\u00ean d\u00f9ng li\u1ec1u th\u1ea5p ho\u1eb7c \u0111i\u1ec1u ch\u1ec9nh vi\u1ec7c m\u1ea5t th\u1ec3 t\u00edch tinh d\u1ecbch th\u1eddi gian \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n

\u0110\u1eb7t ng\u01b0\u1eddi b\u1ec7nh n\u1eb1m ng\u1eeda ho\u1eb7c truy\u1ec1n t\u0129nh m\u1ea1ch n\u01b0\u1edbc mu\u1ed1i sinh l\u00fd n\u1ebfu th\u1ea5y huy\u1ebft \u00e1p gi\u1ea3m.<\/span><\/p>\n

Th\u1eddi gian d\u00f9ng c\u00f3 th\u1ec3 m\u1ec7t, ch\u00f3ng m\u1eb7t n\u00ean c\u1ea7n c\u1ea9n th\u1eadn khi v\u1eadn h\u00e0nh m\u00e1y, l\u00e1i xe.<\/span><\/p>\n

C\u00f3 th\u1ec3 u\u1ed1ng v\u1edbi thu\u1ed1c h\u1ea1 \u00e1p kh\u00e1c.<\/span><\/p>\n

T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/h3>\n\n\n\n\n
Th\u1ea7n kinh<\/span><\/td>\nH\u00f4 h\u1ea5p<\/span><\/td>\nTi\u00eau h\u00f3a<\/span><\/td>\nDa li\u1ec5u<\/span><\/td>\nTi\u1ebft ni\u1ec7u \u2013 Sinh d\u1ee5c<\/span><\/td>\nKh\u00e1c<\/span><\/td>\n<\/tr>\n
\u0110au \u0111\u1ea7u<\/span><\/p>\n

C\u0103ng th\u1eb3ng, lo \u00e2u<\/span><\/td>\n

Vi\u00eam h\u1ecdng<\/span><\/p>\n

Ho<\/span><\/p>\n

B\u1ea5t th\u01b0\u1eddng \u1edf xoang<\/span><\/td>\n

Ti\u00eau ch\u1ea3y<\/span><\/td>\nPh\u00e1t ban<\/span><\/td>\nNhi\u1ec5m tr\u00f9ng ti\u1ebft ni\u1ec7u<\/span><\/td>\nChu\u1ed9t r\u00fat<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n

C\u00e1c t\u01b0\u01a1ng t\u00e1c c\u1ee7a thu\u1ed1c v\u1edbi Nifedipine, Warfarin, Digoxin, Hydrochloride kh\u00f4ng th\u1ea5y x\u1ea3y ra \u0111\u00e1ng k\u1ec3.<\/span><\/p>\n

Khi d\u00f9ng v\u1edbi c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf CYP2C9 th\u1ea5y Irbesartan c\u00f3 th\u1ec3 b\u1ecb \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh chuy\u1ec3n th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a oxy h\u00f3a.<\/span><\/p>\n

Warfarin: B\u1ecb t\u00e1c \u0111\u1ed9ng d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc kh\u00f4ng \u0111\u00e1ng k\u1ec3.<\/span><\/p>\n

C\u00e1c ph\u1ea3n \u1ee9ng t\u01b0\u01a1ng t\u00e1c c\u1ee5 th\u1ec3 kh\u00e1c v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ee9ng nh\u1eadn.<\/span><\/p>\n

L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n

C\u00e1c thu\u1ed1c g\u00e2y t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn h\u1ec7 renin-angiotensin khi d\u00f9ng trong thai k\u1ef3 c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong, bi\u1ebfn ch\u1ee9ng g\u1eb7p ph\u1ea3i \u1edf thai nhi, tr\u1ebb nh\u1ecf. Ch\u00ednh v\u00ec th\u1ebf kh\u00f4ng \u0111\u01b0\u1ee3c u\u1ed1ng thu\u1ed1c v\u00e0 ph\u1ea3i ng\u1eebng ngay n\u1ebfu bi\u1ebft tin mang thai.<\/span><\/p>\n

Thai nhi, tr\u1ebb s\u01a1 sinh c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c t\u1ed5n th\u01b0\u01a1ng nh\u01b0 v\u00f4 ni\u1ec7u, huy\u1ebft \u00e1p gi\u1ea3m, suy th\u1eadn, thi\u1ebfu s\u1ea3n x\u01b0\u01a1ng s\u1ecd, t\u1eed vong khi d\u00f9ng thu\u1ed1c khi mang thai 6 th\u00e1ng cu\u1ed1i thai k\u1ef3. Ngo\u00e0i ra c\u00f3 th\u1ec3 g\u1eb7p thi\u1ebfu \u1ed1i d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ec3u hi\u1ec7n thi\u1ec3u s\u1ea3n ph\u1ed5i, s\u1ecd m\u1eb7t b\u1ecb d\u1ecb d\u1ea1ng, thai nhi co r\u00fat. Ngo\u00e0i ra c\u00f2n ghi nh\u1eadn c\u00e1c bi\u1ec3u hi\u1ec7n c\u00f2n \u1ed1ng \u0111\u1ed9ng m\u1ea1ch, thai ch\u1eadm ph\u00e1t tri\u1ec3n, sinh non.<\/span><\/p>\n

Irbesartan, ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a n\u00f3 ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft c\u00f3 \u1edf s\u1eefa m\u1eb9 kh\u00f4ng nh\u1eefng th\u1ea5y xu\u1ea5t hi\u1ec7n \u1edf chu\u1ed9t m\u1eb9 v\u1edbi n\u1ed3ng \u0111\u1ed9 th\u1ea5p. Ch\u00ednh v\u00ec th\u1ebf mu\u1ed1n u\u1ed1ng thu\u1ed1c ch\u1ee9a Irbesartan c\u1ea7n ng\u1eebng cho tr\u1ebb b\u00fa.<\/span><\/p>\n

Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n

Khi u\u1ed1ng li\u1ec1u cao c\u00f3 th\u1ec3 g\u1eb7p:<\/span><\/p>\n