{"id":50668,"date":"2023-10-25T14:54:03","date_gmt":"2023-10-25T07:54:03","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=50668"},"modified":"2025-07-24T14:00:03","modified_gmt":"2025-07-24T07:00:03","slug":"metsav-500","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/metsav-500\/","title":{"rendered":"Metsav 500"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/metsav-500\/\">Metsav 500<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m SaVi, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-26252-17<\/strong><\/p>\n<h2>Metsav 500 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean <strong>Metsav 500<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: <strong>Metformin 500mg<\/strong>.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-26252-17.<br \/>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.<br \/>\nXu\u1ea5t x\u1ee9: Vi\u1ec7t Nam.<\/p>\n<h2>Thu\u1ed1c Metsav 500 c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Metformin l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng nh\u00f3m biguanid. Metformin l\u00e0m gi\u1ea3m \u0111\u01b0\u1eddng huy\u1ebft nh\u01b0ng kh\u00f4ng g\u00e2y bi\u1ebfn ch\u1ee9ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft. \u1ede ng\u01b0\u1eddi b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type II, Metformin l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 glucose huy\u1ebft t\u01b0\u01a1ng khi \u0111\u00f3i v\u00e0 sau b\u1eefa \u0103n do metformin l\u00e0m t\u0103ng s\u1eed d\u1ee5ng glucose \u1edf t\u1ebf b\u00e0o, t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng li\u00ean k\u1ebft c\u1ee7a insulin v\u1edbi th\u1ee5 th\u1ec3, gi\u1ea3m h\u1ea5p thu glucose \u1edf ru\u1ed9t v\u00e0 \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p glucose \u1edf gan. Ngo\u00e0i ra, metformin c\u00f2n c\u00f3 \u1ea3nh h\u01b0\u1edfng t\u1ed1t tr\u00ean chuy\u1ec3n h\u00f3a lipoprotein &#8211;\u00a0 r\u1ed1i lo\u1ea1n th\u01b0\u1eddng x\u1ea3y ra \u1edf ng\u01b0\u1eddi b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp II. Metformin kh\u00f4ng g\u00e2y t\u0103ng c\u00e2n. D\u00f9ng metformin \u0111\u01a1n tr\u1ecb li\u1ec7u c\u00f3 th\u1ec3 c\u00f3 hi\u1ec7u qu\u1ea3 t\u1ed1t \u0111\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng \u0111\u00e1p \u1ee9ng\/ \u0111\u00e1p \u1ee9ng m\u1ed9t ph\u1ea7n v\u1edbi sulfonylure.<\/p>\n<h3>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu<\/li>\n<\/ul>\n<p>Metformin h\u1ea5p thu kh\u00f4ng ho\u00e0n to\u00e0n v\u00e0 ch\u1eadm \u1edf \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i c\u1ee7a Metformin 500mg u\u1ed1ng l\u00fac \u0111\u00f3i kho\u1ea3ng 50- 60%. S\u1ef1 h\u1ea5p thu metformin b\u1ecb gi\u1ea3m v\u00e0 ch\u1eadm khi d\u00f9ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n.<\/p>\n<ul>\n<li>Ph\u00e2n b\u1ed1<\/li>\n<\/ul>\n<p>Metformin li\u00ean k\u1ebft kh\u00f4ng \u0111\u00e1ng k\u1ec3 v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. Metformin ph\u00e2n b\u1ed1 nhanh v\u00e0o c\u00e1c m\u00f4, d\u1ecbch c\u01a1 th\u1ec3 v\u00e0 v\u00e0o trong h\u1ed3ng c\u1ea7u.<\/p>\n<ul>\n<li>Chuy\u1ec3n h\u00f3a<\/li>\n<\/ul>\n<p>Metformin th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua \u1ed1ng th\u1eadn. Kho\u1ea3ng 90% l\u01b0\u1ee3ng thu\u1ed1c sau khi u\u1ed1ng h\u1ea5p thu v\u00e0 th\u1ea3i tr\u1eeb qua \u0111\u01b0\u1eddng th\u1eadn \u1edf d\u1ea1ng kh\u00f4ng chuy\u1ec3n h\u00f3a sau 1 ng\u00e0y.<\/p>\n<ul>\n<li>Th\u1ea3i tr\u1eeb<\/li>\n<\/ul>\n<p>N\u1eeda \u0111\u1eddi trong huy\u1ebft t\u01b0\u01a1ng l\u00e0 1,5-4,5 gi\u1edd. Suy th\u1eadn c\u00f3 th\u1ec3 g\u00e2y t\u00edch l\u0169y, \u0111\u1ed9 thanh th\u1ea3i gi\u1ea3m \u1edf ng\u01b0\u1eddi suy th\u1eadn v\u00e0 cao tu\u1ed5i.<\/p>\n<h2>Thu\u1ed1c Metsav 500 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb \u0111\u01a1n tr\u1ecb li\u1ec7u \u0110\u00e1i th\u00e1o \u0111\u01b0\u1eddng type II khi kh\u00f4ng \u0111i\u1ec1u ch\u1ec9nh \u0111\u01b0\u1ee3c glucose huy\u1ebft b\u1eb1ng ch\u1ebf \u0111\u1ed9 \u0103n \u0111\u01a1n thu\u1ea7n.<br \/>\nK\u1ebft h\u1ee3p Metformin v\u1edbi m\u1ed9t sulfonylure \u0111\u1ec3 ki\u1ec3m so\u00e1t glucose huy\u1ebft khi ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 d\u00f9ng metformin\/ sulfonylure \u0111\u01a1n thu\u1ea7n kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Metsav 500<\/h2>\n<p>&#8211; Ng\u01b0\u1eddi l\u1edbn: U\u1ed1ng 1 vi\u00ean\/ng\u00e0y v\u00e0o b\u1eefa \u0103n s\u00e1ng. T\u0103ng th\u00eam 1 vi\u00ean\/ng\u00e0y, c\u00e1ch 1 tu\u1ea7n t\u0103ng 1 l\u1ea7n t\u1edbi t\u1ed1i \u0111a 5 vi\u00ean\/ng\u00e0y. T\u1eeb 4 vi\u00ean\/ng\u00e0y c\u00f3 th\u1ec3 chia l\u00e0m 2 l\u1ea7n u\u1ed1ng\/ng\u00e0y. N\u1ebfu d\u00f9ng li\u1ec1u 5 vi\u00ean\/ng\u00e0y thi chia 3 l\u1ea7n\/ng\u00e0y, u\u1ed1ng v\u00e0o b\u1eefa \u0103n.<\/p>\n<p>Li\u1ec1u duy tr\u00ec 2 vi\u00ean\/ng\u00e0y, chia 2 l\u1ea7n v\u00e0o c\u00e1c b\u1eefa \u0103n s\u00e1ng v\u00e0 t\u1ed1i. M\u1ed9t s\u1ed1 ng\u01b0\u1eddi c\u00f3 th\u1ec3 d\u00f9ng 1 vi\u00ean\/l\u1ea7n x 3 l\u1ea7n\/ng\u00e0y (v\u00e0o c\u00e1c b\u1eefa \u0103n).<\/p>\n<p>&#8211; Ng\u01b0\u1eddi cao tu\u1ed5i:<br \/>\nLi\u1ec1u b\u1eaft \u0111\u1ea7u v\u00e0 li\u1ec1u duy tr\u00ec c\u1ea7n th\u1ea5p, kh\u00f4ng n\u00ean \u0111i\u1ec1u tr\u1ecb t\u1edbi li\u1ec1u t\u1ed1i \u0111a.<\/p>\n<p>&#8211; Chuy\u1ec3n t\u1eeb thu\u1ed1c ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng kh\u00e1c sang metformin:<br \/>\nTh\u01b0\u1eddng kh\u00f4ng c\u1ea7n giai \u0111o\u1ea1n chuy\u1ec3n ti\u1ebfp. Tr\u1eeb khi chuy\u1ec3n t\u1eeb clorpropamid sang c\u1ea7n th\u1eadn tr\u1ecdng trong 2 tu\u1ea7n \u0111\u1ea7u v\u00ec c\u00f3 th\u1ec3 g\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<p>&#8211; K\u1ebft h\u1ee3p metformin v\u00e0 sulfonylure u\u1ed1ng:<br \/>\nN\u1ebfu trong 4 tu\u1ea7n \u0111\u1ea7u ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi li\u1ec1u t\u1ed1i \u0111a metformin \u0111\u01a1n, c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c d\u00f9ng metformin v\u1edbi li\u1ec1u t\u1ed1i \u0111a v\u00e0 th\u00eam d\u1ea7n m\u1ed9t sulfonylure u\u1ed1ng.<\/p>\n<p>Khi \u0111i\u1ec1u tr\u1ecb trong 3 th\u00e1ng, v\u1edbi li\u1ec1u t\u1ed1i \u0111a c\u1ee7a c\u00e0 2 thu\u1ed1c m\u00e0 ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng \u0111\u00e1p \u1ee9ng th\u00ec th\u01b0\u1eddng ph\u1ea3i ng\u1eebng v\u00e0 b\u1eaft \u0111\u1ea7u d\u00f9ng insulin.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ecb t\u1ed5n th\u01b0\u01a1ng th\u1eadn ho\u1eb7c gan:<br \/>\nKh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng cho ng\u01b0\u1eddi c\u00f3 b\u1ec7nh th\u1eadn\/suy th\u1eadn v\u00e0 tr\u00e1nh d\u00f9ng cho ng\u01b0\u1eddi b\u1ec7nh gan.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Metsav 500 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Qu\u00e1 m\u1eabn v\u1edbi metformin ho\u1eb7c c\u00e1c th\u00e0nh ph\u1ea7n kh\u00e1c c\u00f3 trong thu\u1ed1c.<\/li>\n<li>B\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m khu\u1ea9n, d\u1ecb h\u00f3a c\u1ea5p, ch\u1ea5n th\u01b0\u01a1ng.<\/li>\n<li>B\u1ec7nh th\u1eadn\/ ch\u1ee9c n\u0103ng th\u1eadn r\u1ed1i lo\u1ea1n.<\/li>\n<li>Nhi\u1ec5m acid chuy\u1ec3n ho\u00e1 c\u1ea5p ho\u1eb7c m\u1ea1n, c\u00f3\/ kh\u00f4ng c\u00f3 h\u00f4n m\u00ea.<\/li>\n<li>B\u1ec7nh r\u1ea5t n\u1eb7ng v\u1ec1 tim m\u1ea1ch, gan, h\u00f4 h\u1ea5p.<\/li>\n<li>Tr\u1ee5y tim m\u1ea1ch, suy tim sung huy\u1ebft, nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p t\u00ednh.<\/li>\n<li>B\u1ec7nh ph\u1ed5i thi\u1ebfu oxy m\u1ea1n.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n huy\u1ebft, nhi\u1ec5m khu\u1ea9n n\u1eb7ng.<\/li>\n<li>M\u1ea5t b\u00f9 chuy\u1ec3n ho\u00e1 c\u1ea5p t\u00ednh.<\/li>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai.<\/li>\n<li>Ng\u01b0\u1eddi b\u1ec7nh ch\u1ee5p X-quang c\u00f3 ti\u00eam ch\u1ea5t c\u1ea3n quang iod.<\/li>\n<li>Ho\u1ea1i th\u01b0, thi\u1ebfu dinh d\u01b0\u1ee1ng, nghi\u1ec7n r\u01b0\u1ee3u.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Metsav 500<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Theo d\u00f5i th\u01b0\u1eddng xuy\u00ean c\u00e1c x\u00e9t nghi\u1ec7m c\u1eadn l\u00e2m s\u00e0ng \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh li\u1ec1u metformin t\u1ed1i thi\u1ec3u c\u00f3 hi\u1ec7u qu\u1ea3. Th\u00f4ng b\u00e1o v\u1ec1 nguy c\u01a1 nhi\u1ec5m acid lactic cho ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb b\u1eb1ng metformin c\u1ea7n k\u1ebft h\u1ee3p v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n h\u1ee3p l\u00fd.<\/p>\n<p>Nguy c\u01a1 t\u00edch l\u0169y v\u00e0 nhi\u1ec5m acid lactic t\u0103ng theo m\u1ee9c \u0111\u1ed9 suy th\u1eadn.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn kh\u00f4ng n\u00ean d\u00f9ng metformin.<\/p>\n<p>2 &#8211; 3 ng\u00e0y tr\u01b0\u1edbc khi ch\u1ee5p X-quang c\u00f3 s\u1eed d\u1ee5ng ch\u1ea5t c\u1ea3n quang iod c\u1ea7n ng\u1eebng \u0111i\u1ec1u tr\u1ecb v\u1edbi metformin, v\u00e0 c\u1ea3 2 ng\u00e0y sau khi chi\u1ebfu ch\u1ee5p. D\u00f9ng tr\u1edf l\u1ea1i sau khi \u0111\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng.<\/p>\n<p>C\u00f3 \u00fd ki\u1ebfn cho r\u1eb1ng d\u00f9ng thu\u1ed1c u\u1ed1ng \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng so v\u1edbi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng ch\u1ebf \u0111\u1ed9 \u0103n \u0111\u01a1n thu\u1ea7n ho\u1eb7c ph\u1ed1i h\u1ee3p insulin v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n, l\u00e0m t\u0103ng nguy c\u01a1 t\u1eed vong v\u1ec1 tim m\u1ea1ch.<\/p>\n<p>S\u1eed d\u1ee5ng metformin \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c c\u00f3 t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn ch\u1ee9c n\u0103ng th\u1eadn c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 ph\u00e2n b\u1ed1 metformin.<\/p>\n<p>Khi ti\u1ebfn h\u00e0nh c\u00e1c ph\u1eabu thu\u1eadt c\u1ea7n ng\u01b0ng s\u1eed d\u1ee5ng metformin.<\/p>\n<p>Kh\u00f4ng d\u00f9ng cho ng\u01b0\u1eddi b\u1ec7nh suy gi\u1ea3m ch\u1ee9c n\u0103ng gan.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<table style=\"border-collapse: collapse;width: 100%;height: 189px\">\n<tbody>\n<tr style=\"height: 21px\">\n<td style=\"width: 20.3626%;text-align: center;height: 21px\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/td>\n<td style=\"width: 20.3626%;text-align: center;height: 21px\">C\u01a1 quan<\/td>\n<td style=\"width: 59.2747%;text-align: center;height: 21px\">Bi\u1ec3u hi\u1ec7n<\/td>\n<\/tr>\n<tr style=\"height: 43px\">\n<td style=\"width: 20.3626%;height: 85px;text-align: center\" rowspan=\"3\">Th\u01b0\u1eddng g\u1eb7p<\/td>\n<td style=\"width: 20.3626%;height: 43px\">Ti\u00eau h\u00f3a<\/td>\n<td style=\"width: 59.2747%;height: 43px\">Ch\u00e1n \u0103n, n\u00f4n, bu\u1ed3n n\u00f4n; \u0111\u1ea7y th\u01b0\u1ee3ng v\u1ecb, ti\u00eau ch\u1ea3y; t\u00e1o b\u00f3n, \u1ee3 n\u00f3ng.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 20.3626%;height: 21px\">Da<\/td>\n<td style=\"width: 59.2747%;height: 21px\">Ban, nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng, m\u1ec1 \u0111ay.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 20.3626%;height: 21px\">Chuy\u1ec3n ho\u00e1<\/td>\n<td style=\"width: 59.2747%;height: 21px\">Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 vitamin B12.<\/td>\n<\/tr>\n<tr style=\"height: 62px\">\n<td style=\"width: 20.3626%;height: 83px;text-align: center\" rowspan=\"2\">\u00cdt g\u1eb7p<\/td>\n<td style=\"width: 20.3626%;height: 62px\">Huy\u1ebft h\u1ecdc<\/td>\n<td style=\"width: 59.2747%;height: 62px\">Thi\u1ebfu m\u00e1u b\u1ea5t s\u1ea3n, thi\u1ebfu m\u00e1u tan huy\u1ebft, suy t\u1ee7y, gi\u1ea3m ti\u1ec3u c\u1ea7u, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 20.3626%;height: 21px\">Chuy\u1ec3n ho\u00e1<\/td>\n<td style=\"width: 59.2747%;height: 21px\">Nhi\u1ec5m acid lactic.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>&#8211; Gi\u1ea3m t\u00e1c d\u1ee5ng:<\/p>\n<p>Nh\u1eefng thu\u1ed1c g\u00e2y t\u0103ng glucose huy\u1ebft ( corticosteroid, phenothiazin, phenytoin, acid nicotinic, thu\u1ed1c l\u1ee3i ti\u1ec3u, ch\u1ebf ph\u1ea9m tuy\u1ebfn gi\u00e1p, thu\u1ed1c tr\u00e1nh th\u1ee5 thai u\u1ed1ng, oestrogen, thu\u1ed1c t\u00e1c d\u1ee5ng gi\u1ed1ng th\u1ea7n kinh giao c\u1ea3m, thu\u1ed1c ch\u1eb9n k\u00eanh calci, isoniazid) c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m ki\u1ec3m so\u00e1t glucose huy\u1ebft.<\/p>\n<p>&#8211; T\u0103ng t\u00e1c d\u1ee5ng:<\/p>\n<p>Furosemid d\u00f9ng c\u00f9ng v\u1edbi metformin l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 trong m\u00e1u c\u1ee7a metformin.<\/p>\n<p>&#8211; T\u0103ng \u0111\u1ed9c t\u00ednh:<\/p>\n<p>Nh\u1eefng thu\u1ed1c cationic (v\u00ed d\u1ee5 digoxin, amilorid, morphin, procainamid, ranitidin, triamteren, quinidin, vancomycin, trimethoprim, quinin) c\u00f3 kh\u1ea3 n\u0103ng t\u01b0\u01a1ng t\u00e1c v\u1edbi metformin.<br \/>\nCimetidin l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u1ee7a metformin trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 m\u00e1u to\u00e0n ph\u1ea7n (60%).<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef mang thai<\/li>\n<\/ul>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng metformin.<\/p>\n<ul>\n<li>Ng\u01b0\u1eddi cho con b\u00fa<\/li>\n<\/ul>\n<p>Metformin c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft \u0111\u01b0\u1ee3c v\u00e0o s\u1eefa m\u1eb9, c\u00e2n nh\u1eafc ng\u1eebng cho con b\u00fa khi d\u00f9ng thu\u1ed1c ho\u1eb7c ng\u01b0\u1ee3c l\u1ea1i.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Sau khi u\u1ed1ng 85g metformin kh\u00f4ng th\u1ea5y gi\u1ea3m \u0111\u01b0\u1eddng huy\u1ebft, ch\u1ec9 th\u1ea5y nhi\u1ec5m acid lactic.<\/p>\n<p>Th\u1ea9m ph\u00e2n m\u00e1u c\u00f3 th\u1ec3 c\u00f3 t\u00e1c d\u1ee5ng khi d\u00f9ng thu\u1ed1c qu\u00e1 li\u1ec1u.<\/p>\n<h3>T\u00e1c \u0111\u1ed9ng tr\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h2>Thu\u1ed1c Metsav 500 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Metsav 500<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/gregory-4\/\">Gregory 4<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa, ch\u1ee9a Glimepiride v\u1edbi h\u00e0m l\u01b0\u1ee3ng 4mg. Thu\u1ed1c d\u00f9ng \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2 \u1edf ng\u01b0\u1eddi l\u1edbn, h\u1ed7 tr\u1ee3 cho ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang, \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi Metfomin. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n, v\u1edbi li\u1ec1u kh\u1edfi \u0111\u1ea7u l\u00e0 1mg\/ng\u00e0y.<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/panfor-sr\/\">Panfor SR<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m An Thi\u00ean ch\u1ee9a Metformin v\u1edbi h\u00e0m l\u01b0\u1ee3ng 500 mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2 c\u00f3 th\u1eeba c\u00e2n b\u00e9o ph\u00ec. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean n\u00e9n t\u00e1c d\u1ee5ng k\u00e9o d\u00e0i v\u00e0 c\u00f3 gi\u00e1 kho\u1ea3ng 120.000 \u0111\u1ed3ng\/ 1 h\u1ed9p 5 v\u1ec9 x 20 vi\u00ean.<\/p>\n<h2>T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Metsav 500?<\/h2>\n<table style=\"border-collapse: collapse;width: 100%;height: 191px\">\n<tbody>\n<tr style=\"height: 21px\">\n<td style=\"width: 53.9052%;height: 21px;text-align: center\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 46.0948%;height: 21px;text-align: center\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr style=\"height: 64px\">\n<td style=\"width: 53.9052%;height: 64px\">Metformin \u0111\u00e3 \u0111\u01b0\u1ee3c C\u01a1 quan Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) ph\u00ea duy\u1ec7t v\u00e0o n\u0103m 1994 \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2.<\/td>\n<td style=\"width: 46.0948%;height: 64px\">C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean \u0111\u01b0\u1eddng ti\u00eau h\u00f3a nh\u01b0 ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n v\u00e0 n\u00f4n l\u00e0 t\u01b0\u01a1ng \u0111\u1ed1i ph\u1ed5 bi\u1ebfn.<\/td>\n<\/tr>\n<tr style=\"height: 64px\">\n<td style=\"width: 53.9052%;height: 64px\">Metformin hi\u1ec7n l\u00e0 thu\u1ed1c tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng duy nh\u1ea5t d\u00e0nh cho b\u1ec7nh nh\u00e2n ti\u1ec1n ti\u1ec3u \u0111\u01b0\u1eddng \u0111\u01b0\u1ee3c Hi\u1ec7p h\u1ed9i Ti\u1ec3u \u0111\u01b0\u1eddng Hoa K\u1ef3 (ADA) khuy\u00ean d\u00f9ng.<\/td>\n<td style=\"width: 46.0948%;height: 64px\">Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng metformin cho ph\u1ee5 n\u1eef c\u00f3 thai.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 53.9052%;height: 21px\">Metformin th\u01b0\u1eddng \u0111\u01b0\u1ee3c coi l\u00e0 an to\u00e0n v\u00e0 dung n\u1ea1p t\u1ed1t.<\/td>\n<td style=\"width: 46.0948%;height: 21px\"><\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 53.9052%;height: 21px\">Metsav 500 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m SaVi &#8211; l\u00e0 th\u01b0\u01a1ng hi\u1ec7u h\u00e0ng \u0111\u1ea7u trong l\u0129nh v\u1ef1c s\u1ea3n xu\u1ea5t, ph\u00e2n ph\u1ed1i D\u01b0\u1ee3c ph\u1ea9m t\u1ea1i Vi\u1ec7t Nam.<\/td>\n<td style=\"width: 46.0948%;height: 21px\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u00e1c gi\u1ea3 Calette Corcoran v\u00e0 c\u1ed9ng s\u1ef1 (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 17 th\u00e1ng 08 n\u0103m 2023). <em>Metformin<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 25 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30085525\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30085525\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 Elizabeth Sanchez-Rangel v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 09 n\u0103m 2017). <em>Metformin: clinical use in type 2 diabetes<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 25 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28770321\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28770321\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 Dmitri Kirpichnikov v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 07 n\u0103m 2002). <em>Metformin: an update<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 25 th\u00e1ng 10 n\u0103m 2023, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12093242\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/12093242\/<\/a><\/li>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i b\u1ea3n PDF <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2023\/10\/Metsav-500-vnras.pdf\">T\u1ea0I \u0110\u00c2Y<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Metsav 500 ch\u1ee9a Metformin h\u00e0m l\u01b0\u1ee3ng 500mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type II khi kh\u00f4ng \u0111i\u1ec1u ch\u1ec9nh \u0111\u01b0\u1ee3c glucose huy\u1ebft b\u1eb1ng ch\u1ebf \u0111\u1ed9 \u0103n \u0111\u01a1n thu\u1ea7n ho\u1eb7c k\u1ebft h\u1ee3p v\u1edbi m\u1ed9t sulfonylure \u0111\u1ec3 ki\u1ec3m so\u00e1t glucose huy\u1ebft khi ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 d\u00f9ng metformin\/ sulfonylure \u0111\u01a1n thu\u1ea7n kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3<\/p>\n","protected":false},"author":490,"featured_media":50683,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-50668","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/50668","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=50668"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/50683"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=50668"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=50668"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=50668"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}