{"id":50374,"date":"2023-10-21T15:36:13","date_gmt":"2023-10-21T08:36:13","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=50374"},"modified":"2025-07-24T14:00:05","modified_gmt":"2025-07-24T07:00:05","slug":"coxnis","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/coxnis\/","title":{"rendered":"Coxnis"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/coxnis\/\">Coxnis<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-31633-19<\/strong><\/p>\n<h2>Coxnis l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean <strong>Coxnis<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: <strong>Meloxicam 7,5mg<\/strong>.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-31633-19.<br \/>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 10 vi\u00ean.<br \/>\nXu\u1ea5t x\u1ee9: Vi\u1ec7t Nam.<\/p>\n<h2>Thu\u1ed1c Coxnis c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Meloxicam l\u00e0 m\u1ed9t d\u1eabn xu\u1ea5t oxicam c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 s\u1ed1t, gi\u1ea3m \u0111au v\u00e0 ch\u1ed1ng vi\u00eam. Meloxicam ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch l\u00e0m gi\u1ea3m t\u1ed5ng h\u1ee3p prostaglandin (li\u00ean quan \u0111\u1ebfn qu\u00e1 tr\u00ecnh vi\u00eam, s\u1ed1t, \u0111au) do \u1ee9c ch\u1ebf cyclooxygenase (COX).<\/p>\n<p>Meloxicam \u1ee9c ch\u1ebf \u01b0u ti\u00ean tr\u00ean COX-2. Li\u1ec1u d\u00f9ng v\u00e0 s\u1ef1 kh\u00e1c nhau gi\u1eefa c\u00e1c c\u00e1 th\u1ec3 ng\u01b0\u1eddi b\u1ec7nh \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn m\u1ee9c \u0111\u1ed9 \u1ee9c ch\u1ebf COX-1. Li\u1ec1u 15 mg\/ ng\u00e0y \u1ee9c ch\u1ebf COX-1 nhi\u1ec1u h\u01a1n li\u1ec1u 7,5 mg\/ ng\u00e0y. C\u1ea3 hai li\u1ec1u n\u00e0y c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u do \u1ee9c ch\u1ebf COX-1 tr\u00ean ti\u1ec3u c\u1ea7u. So v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf kh\u00f4ng ch\u1ecdn l\u1ecdc COX, Meloxicam \u00edt c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean ti\u00eau h\u00f3a h\u01a1n.<\/p>\n<h3>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu<\/li>\n<\/ul>\n<p>Meloxicam h\u1ea5p thu t\u1ed1t v\u00e0 k\u00e9o d\u00e0i qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u1edbi sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 89%. Sau khi u\u1ed1ng v\u00e0o l\u00fac \u0111\u00f3i, n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trung b\u00ecnh \u0111\u1ea1t \u0111\u01b0\u1ee3c l\u00e0 4 &#8211; 5. V\u00e0o ng\u00e0y th\u1ee9 5 khi u\u1ed1ng li\u1ec1u l\u1eb7p l\u1ea1i, thu\u1ed1c \u0111\u1ea1t tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh<\/p>\n<p>S\u1ef1 h\u1ea5p thu c\u1ee7a thu\u1ed1c \u00edt b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n. Cmax t\u0103ng kho\u1ea3ng 22%, Tmax t\u1eeb 5 &#8211; 6 gi\u1edd, AUC kh\u00f4ng thay \u0111\u1ed5i khi u\u1ed1ng vi\u00ean nang meloxicam sau b\u1eefa \u0103n s\u00e1ng b\u00e9o. Cmax v\u00e0 AUC kh\u00f4ng \u0111\u1ed5i, Tmax t\u0103ng l\u00ean t\u1edbi kho\u1ea3ng 7 gi\u1edd khi u\u1ed1ng d\u1ea1ng dung d\u1ecbch. Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc v\u1edbi antacid.<\/p>\n<ul>\n<li>Ph\u00e2n b\u1ed1<\/li>\n<\/ul>\n<p>Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 trung b\u00ecnh kho\u1ea3ng 10 L. Kho\u1ea3ng 99,4% thu\u1ed1c g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (ch\u1ee7 y\u1ebfu l\u00e0 albumin). T\u1ef7 l\u1ec7 g\u1eafn k\u1ebft protein kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o n\u1ed3ng \u0111\u1ed9 v\u00e0 gi\u1ea3m xu\u1ed1ng kho\u1ea3ng 99% \u1edf b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh th\u1eadn. Sau khi u\u1ed1ng, meloxicam ph\u00e2n b\u1ed1 v\u00e0o h\u1ed3ng c\u1ea7u ng\u01b0\u1eddi v\u1edbi n\u1ed3ng \u0111\u1ed9 &lt; 10%, &gt; 90% li\u1ec1u ph\u00f3ng x\u1ea1 d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng thay \u0111\u1ed5i \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n trong huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 meloxicam trong d\u1ecbch kh\u1edbp sau khi d\u00f9ng li\u1ec1u \u0111\u01a1n kho\u1ea3ng 40 &#8211; 50% n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng. T\u1ef7 l\u1ec7 d\u1ea1ng t\u1ef1 do trong huy\u1ebft t\u01b0\u01a1ng th\u1ea5p h\u01a1n 2,5 l\u1ea7n so v\u1edbi trong d\u1ecbch kh\u1edbp.<\/p>\n<ul>\n<li>Chuy\u1ec3n h\u00f3a<\/li>\n<\/ul>\n<p>Meloxicam chuy\u1ec3n m\u1ea1nh \u1edf gan d\u01b0\u1edbi s\u1ef1 x\u00fac t\u00e1c ch\u1ee7 y\u1ebfu c\u1ee7a CYP2C9 v\u00e0 m\u1ed9t ph\u1ea7n nh\u1ecf c\u1ee7a CYP3A4 th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a 5\u2019-carboxymeloxicam (60% li\u1ec1u), \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1edfi s\u1ef1 oxy h\u00f3a 5\u2019-hydroxymethylmeloxicam, ch\u1ea5t n\u00e0y c\u0169ng th\u1ea3i tr\u1eeb \u1edf m\u1ed9t m\u1ee9c \u0111\u1ed9 th\u1ea5p h\u01a1n (9% li\u1ec1u). Ho\u1ea1t t\u00ednh c\u1ee7a peroxidase c\u1ee7a 2 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f2n l\u1ea1i chi\u1ebfm 16% v\u00e0 4% li\u1ec1u d\u00f9ng t\u01b0\u01a1ng \u1ee9ng. C\u00e1c chuy\u1ec3n h\u00f3a \u0111\u1ec1u kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd.<\/p>\n<ul>\n<li>Th\u1ea3i tr\u1eeb<\/li>\n<\/ul>\n<p>Meloxicam th\u1ea3i tr\u1eeb v\u1edbi l\u01b0\u1ee3ng nh\u01b0 nhau qua ph\u00e2n v\u00e0 n\u01b0\u1edbc ti\u1ec3u, ch\u1ee7 y\u1ebfu d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a,. T\u1ef7 l\u1ec7 thu\u1ed1c ch\u01b0a chuy\u1ec3n h\u00f3a trong n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n v\u00e0 l\u1ea7n l\u01b0\u1ee3t l\u00e0 0,2% v\u00e0 1,6%. Thu\u1ed1c th\u1ea3i tr\u1eeb \u0111\u00e1ng k\u1ec3 qua m\u1eadt v\u00e0\/ ho\u1eb7c \u0111\u01b0\u1eddng ru\u1ed9t.<\/p>\n<p>Th\u1eddi gian b\u00e1n th\u1ea3i trong kho\u1ea3ng 15 &#8211; 20 gi\u1edd, kh\u00f4ng ph\u1ee5 thu\u1ed9c li\u1ec1u \u0111i\u1ec1u tr\u1ecb. \u0110\u1ed9 thanh th\u1ea3i trong huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 7 &#8211; 9 mL\/ ph\u00fat.<\/p>\n<h2>Thu\u1ed1c Coxnis \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Thu\u1ed1c Coxnis<\/strong> d\u00f9ng \u0111i\u1ec1u tr\u1ecb l\u00e2u d\u00e0i b\u1ec7nh vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp, tho\u00e1i h\u00f3a kh\u1edbp, b\u1ec7nh kh\u1edbp m\u1ea1n t\u00ednh kh\u00e1c v\u00e0 vi\u00eam kh\u1edbp \u1edf thanh thi\u1ebfu ni\u00ean.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Coxnis<\/h2>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c u\u1ed1ng ngay sau b\u1eefa \u0103n v\u1edbi n\u01b0\u1edbc v\u00e0o c\u00f9ng m\u1ed9t th\u1eddi \u0111i\u1ec3m m\u1ed7i ng\u00e0y<\/p>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn<\/li>\n<\/ul>\n<p>Vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp, vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p: Kh\u1edfi \u0111\u1ea7u 1 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y, t\u1ed1i \u0111a 2 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y.<br \/>\n\u0110i\u1ec1u tr\u1ecb d\u00e0i ng\u00e0y, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi cao tu\u1ed5i\/ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 tai bi\u1ebfn ph\u1ee5, li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 1 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y.<br \/>\nKh\u00f4ng \u0111\u01b0\u1ee3c u\u1ed1ng qu\u00e1 2 vi\u00ean\/ ng\u00e0y.<br \/>\n\u0110\u1ee3t \u0111au c\u1ea5p trong tho\u00e1i h\u00f3a kh\u1edbp: 1 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y, c\u00f3 th\u1ec3 t\u0103ng t\u1edbi 2 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y n\u1ebfu c\u1ea7n.<\/p>\n<ul>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i:1 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y.<\/li>\n<li>Suy gan, suy th\u1eadn<\/li>\n<\/ul>\n<p>M\u1ee9c \u0111\u1ed9 nh\u1eb9 v\u00e0 v\u1eeba th\u00ec kh\u00f4ng c\u1ea7n ph\u1ea3i \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u. Kh\u00f4ng d\u00f9ng n\u1ebfu suy n\u1eb7ng.<br \/>\nSuy th\u1eadn ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o: kh\u00f4ng qu\u00e1 1 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y.<\/p>\n<ul>\n<li>Tr\u1ebb em tr\u00ean 2 tu\u1ed5i: Li\u1ec1u d\u00f9ng 0,125 mg\/ kg\/ ng\u00e0y, t\u1ed1i \u0111a kh\u00f4ng qu\u00e1 2 vi\u00ean\/ ng\u00e0y.<\/li>\n<\/ul>\n<p>H\u01b0\u1edbng d\u1eabn li\u1ec1u c\u1ee5 th\u1ec3:<\/p>\n<p>Tr\u1ebb t\u1eeb 60 kg tr\u1edf l\u00ean: 1 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y.<\/p>\n<p>Tr\u1ebb d\u01b0\u1edbi 60 kg: Kh\u00f4ng d\u00f9ng thu\u1ed1c n\u00e0y.<\/p>\n<p>Tr\u1ebb em &lt; 2 tu\u1ed5i: ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Coxnis trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>M\u1eabn c\u1ea3m v\u1edbi b\u1ea5t c\u1ee9 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c, c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi aspirin ho\u1eb7c c\u00e1c thu\u1ed1c NSAID kh\u00e1c.<\/p>\n<p>Hen ph\u1ebf qu\u1ea3n, m\u00e0y \u0111ay, ph\u00f9 m\u1ea1ch th\u1ea7n kinh ho\u1eb7c b\u1ecb ph\u00f9 Quincke, polyp m\u0169i xu\u1ea5t hi\u1ec7n khi d\u00f9ng aspirin ho\u1eb7c c\u00e1c NSAID kh\u00e1c.<\/p>\n<p>Lo\u00e9t d\u1ea1 d\u00e0y &#8211; t\u00e1 tr\u00e0ng ti\u1ebfn tri\u1ec3n.<\/p>\n<p>Ch\u1ea3y m\u00e1u n\u00e3o, ch\u1ea3y m\u00e1u d\u1ea1 d\u00e0y.<\/p>\n<p>Sau ph\u1eabu thu\u1eadt b\u1eafc c\u1ea7u n\u1ed1i m\u1ea1ch v\u00e0nh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb \u0111au.<\/p>\n<p>Suy gan\/suy th\u1eadn n\u1eb7ng (kh\u00f4ng ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o).<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa.<\/p>\n<p>Tr\u1ebb em &lt; 2 tu\u1ed5i.<\/p>\n<p>Vi\u00eam ru\u1ed9t (b\u1ec7nh Crohn ho\u1eb7c vi\u00eam lo\u00e9t \u0111\u1ea1i tr\u00e0ng).<\/p>\n<p>Suy tim n\u1eb7ng kh\u00f4ng ki\u1ec3m so\u00e1t.<\/p>\n<p>S\u1eed d\u1ee5ng c\u00f9ng v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf CYP2C9.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Coxnis<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i tim m\u1ea1ch<\/li>\n<\/ul>\n<p>Bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i tim m\u1ea1ch (\u0111\u1ed9t qu\u1ef5, nh\u1ed3i m\u00e1u c\u01a1 tim c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u1eed vong) c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n khi d\u00f9ng NSAIDs, ch\u1ee7 y\u1ebfu khi d\u00f9ng li\u1ec1u cao, xu\u1ea5t hi\u1ec7n trong v\u00e0i tu\u1ea7n \u0111\u1ea7u v\u00e0 t\u0103ng theo th\u1eddi gian d\u00f9ng. C\u1ea7n \u0111\u00e1nh gi\u00e1 \u0111\u1ecbnh k\u1ef3 v\u00e0 th\u0103m kh\u00e1m ngay khi xu\u1ea5t hi\u1ec7n c\u00e1c y\u1ebfu t\u1ed1 n\u00e0y. \u0110\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 c\u1ea7n s\u1eed d\u1ee5ng li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 hi\u1ec7u qu\u1ea3, trong th\u1eddi gian ng\u1eafn nh\u1ea5t.<\/p>\n<ul>\n<li>Ch\u1ea3y m\u00e1u, lo\u00e9t v\u00e0 th\u1ee7ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a<\/li>\n<\/ul>\n<p>Meloxicam c\u00f3 th\u1ec3 g\u00e2y bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng tr\u00ean \u0111\u01b0\u1eddng ti\u00eau h\u00f3a b\u1ea5t c\u1ee9 khi n\u00e0o, c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 tri\u1ec7u ch\u1ee9ng c\u1ea3nh b\u00e1o.<\/p>\n<p>\u0110\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 n\u00e0y c\u1ea7n: S\u1eed d\u1ee5ng li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 hi\u1ec7u qu\u1ea3, trong th\u1eddi gian ng\u1eafn nh\u1ea5t. Kh\u00f4ng d\u00f9ng ph\u1ed1i h\u1ee3p t\u1eeb 2 NSAIDs tr\u1edf l\u00ean m\u1ed9t l\u00fac. H\u1ea1n ch\u1ebf d\u00f9ng \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 g\u1eb7p v\u1ea5n \u0111\u1ec1 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Theo d\u00f5i khi s\u1eed d\u1ee5ng, n\u1ebfu nghi ng\u1edd c\u00f3 bi\u1ebfn c\u1ed1 c\u1ea7n d\u1eebng s\u1eed d\u1ee5ng v\u00e0 ti\u1ebfn h\u00e0nh \u0111\u00e1nh gi\u00e1.<\/p>\n<ul>\n<li>T\u0103ng huy\u1ebft \u00e1p<\/li>\n<\/ul>\n<p>D\u00f9ng Meloxicam huy\u1ebft \u00e1p c\u00f3 th\u1ec3 t\u0103ng ho\u1eb7c l\u00e0m b\u1ec7nh t\u0103ng huy\u1ebft \u00e1p n\u1eb7ng th\u00eam, do \u0111\u00f3 c\u1ea7n th\u01b0\u1eddng xuy\u00ean theo d\u00f5i huy\u1ebft \u00e1p khi d\u00f9ng thu\u1ed1c.<\/p>\n<ul>\n<li>\u1ea2nh h\u01b0\u1edfng tr\u00ean gan<\/li>\n<\/ul>\n<p>Meloxicam c\u00f3 th\u1ec3 g\u00e2y t\u0103ng nh\u1eb9 transaminase ho\u1eb7c c\u00e1c th\u00f4ng s\u1ed1 ch\u1ee9c n\u0103ng gan. Ng\u1eebng d\u00f9ng meloxicam khi c\u00e1c th\u00f4ng s\u1ed1 n\u00e0y t\u0103ng k\u00e9o d\u00e0i ho\u1eb7c t\u0103ng cao \u1edf m\u1ee9c \u0111\u1ed9 c\u00f3 \u00fd ngh\u0129a.<\/p>\n<p>Kh\u00f4ng c\u1ea7n gi\u1ea3m li\u1ec1u \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ec7nh x\u01a1 gan giai \u0111o\u1ea1n \u1ed5n \u0111\u1ecbnh.<\/p>\n<ul>\n<li>Suy tim v\u00e0 ph\u00f9<\/li>\n<\/ul>\n<p>Thu\u1ed1c l\u00e0m t\u0103ng nguy c\u01a1 gi\u1eef n\u01b0\u1edbc v\u00e0 ph\u00f9, suy tim, nh\u1ed3i m\u00e1u c\u01a1 tim, th\u1eadm ch\u00ed t\u1eed vong. S\u1eed d\u1ee5ng meloxicam c\u00f3 th\u1ec3 gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u1ee3i ti\u1ec3u, thu\u1ed1c \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 angiotensin, thu\u1ed1c \u1ee9c ch\u1ebf ACE.<\/p>\n<p>V\u00ec v\u1eady kh\u00f4ng s\u1eed d\u1ee5ng meloxicam \u1edf b\u1ec7nh nh\u00e2n suy tim n\u1eb7ng, tr\u1eeb khi l\u1ee3i \u00edch l\u1edbn nguy c\u01a1. Theo d\u00f5i d\u1ea5u hi\u1ec7u suy tim n\u1ebfu s\u1eed d\u1ee5ng meloxicam \u1edf b\u1ec7nh nh\u00e2n suy tim n\u1eb7ng.<\/p>\n<ul>\n<li>\u0110\u1ed9c t\u00ednh tr\u00ean th\u1eadn v\u00e0 t\u0103ng kali huy\u1ebft<\/li>\n<\/ul>\n<p>\u0110\u1ed9c t\u00ednh tr\u00ean th\u1eadn<br \/>\nS\u1eed d\u1ee5ng l\u00e2u d\u00e0i meloxicam g\u00e2y ho\u1ea1i t\u1eed nh\u00fa th\u1eadn, suy th\u1eadn c\u1ea5p, suy th\u1eadn v\u00e0 c\u00e1c t\u1ed5n th\u01b0\u01a1ng th\u1eadn kh\u00e1c.<br \/>\nN\u00ean theo d\u00f5i d\u1ea5u hi\u1ec7u b\u1ec7nh th\u1eadn n\u1eb7ng h\u01a1n, theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn ho\u1eb7c suy tim, suy gan, m\u1ea5t n\u01b0\u1edbc, ho\u1eb7c gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n khi d\u00f9ng meloxicam \u1edf b\u1ec7nh nh\u00e2n.<\/p>\n<p>T\u0103ng kali huy\u1ebft<br \/>\nS\u1eed d\u1ee5ng thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 kali huy\u1ebft thanh.<\/p>\n<ul>\n<li>Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn<\/li>\n<\/ul>\n<p>Meloxicam l\u00e0m n\u1eb7ng th\u00eam ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn \u1edf b\u1ec7nh nh\u00e2n c\u00f3\/kh\u00f4ng qu\u00e1 m\u1eabn v\u1edbi meloxicam v\u00e0 b\u1ec7nh nh\u00e2n hen suy\u1ec5n nh\u1ea1y c\u1ea3m aspirin.<\/p>\n<ul>\n<li>L\u00e0m n\u1eb7ng th\u00eam hen suy\u1ec5n li\u00ean quan nh\u1ea1y c\u1ea3m aspirin<\/li>\n<\/ul>\n<p>Theo d\u00f5i nh\u1eefng thay \u0111\u1ed5i v\u1ec1 d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng hen suy\u1ec5n khi d\u00f9ng meloxicam cho b\u1ec7nh nh\u00e2n hen suy\u1ec5n.<\/p>\n<ul>\n<li>Ph\u1ea3n \u1ee9ng da nghi\u00eam tr\u1ecdng<\/li>\n<\/ul>\n<p>Ph\u1ea3n \u1ee9ng da nghi\u00eam tr\u1ecdng nh\u01b0 h\u1ed9i ch\u1ee9ng Stevens-Johnson, vi\u00eam da tr\u00f3c v\u1ea3y v\u00e0 ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c, c\u00f3 th\u1ec3 t\u1eed vong. Ng\u1eebng d\u00f9ng meloxicam khi c\u00f3 d\u1ea5u hi\u1ec7u c\u1ee7a ban da ho\u1eb7c qu\u00e1 m\u1eabn.<\/p>\n<ul>\n<li>\u0110\u1ed9c t\u00ednh tr\u00ean m\u00e1u<\/li>\n<\/ul>\n<p>Thi\u1ebfu m\u00e1u c\u00f3 th\u1ec3 x\u1ea3y ra khi d\u00f9ng thu\u1ed1c. Theo d\u00f5i hemoglobin ho\u1eb7c hematocrit n\u1ebfu b\u1ec7nh nh\u00e2n c\u00f3 b\u1ea5t c\u1ee9 d\u1ea5u hi\u1ec7u thi\u1ebfu m\u00e1u n\u00e0o.<\/p>\n<ul>\n<li>Che gi\u1ea5u vi\u00eam v\u00e0 s\u1ed1t<\/li>\n<\/ul>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a c\u00e1c d\u1ea5u hi\u1ec7u ch\u1ea9n \u0111o\u00e1n nhi\u1ec5m tr\u00f9ng.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<table style=\"border-collapse: collapse;width: 100%;height: 274px\">\n<tbody>\n<tr style=\"height: 21px\">\n<td style=\"width: 27.2664%;height: 21px;text-align: center\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/td>\n<td style=\"width: 72.7336%;height: 21px;text-align: center\">Bi\u1ec3u hi\u1ec7n<\/td>\n<\/tr>\n<tr style=\"height: 43px\">\n<td style=\"width: 27.2664%;height: 43px\">R\u1ea5t th\u01b0\u1eddng g\u1eb7p<\/td>\n<td style=\"width: 72.7336%;height: 43px\">Ti\u00eau h\u00f3a: Kh\u00f3 ti\u00eau, n\u00f4n, bu\u1ed3n n\u00f4n, t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 27.2664%;height: 21px\">Th\u01b0\u1eddng g\u1eb7p<\/td>\n<td style=\"width: 72.7336%;height: 21px\">Th\u1ea7n kinh: Nh\u1ee9c \u0111\u1ea7u<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 27.2664%;height: 21px\" rowspan=\"9\">\u00cdt g\u1eb7p<\/td>\n<td style=\"width: 72.7336%;height: 21px\">M\u00e1u v\u00e0 h\u1ec7 b\u1ea1ch huy\u1ebft: Thi\u1ebfu m\u00e1u.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 72.7336%;height: 21px\">Mi\u1ec5n d\u1ecbch: d\u1ecb \u1ee9ng.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 72.7336%;height: 21px\">Th\u1ea7n kinh: bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 72.7336%;height: 21px\">Tai: Hoa m\u1eaft.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 72.7336%;height: 21px\">M\u1ea1ch m\u00e1u: \u0111\u1ecf b\u1eebng, t\u0103ng huy\u1ebft \u00e1p.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 72.7336%;height: 21px\">Ti\u00eau h\u00f3a: Ch\u1ea3y m\u00e1u nhi\u1ec1u \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, vi\u00eam mi\u1ec7ng, \u1ee3 h\u01a1i, vi\u00eam d\u1ea1 d\u00e0y<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 72.7336%;height: 21px\">Gan m\u1eadt: R\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 72.7336%;height: 21px\">Da v\u00e0 c\u00e1c m\u00f4 d\u01b0\u1edbi da: Ph\u00f9 m\u1ea1ch, ph\u00e1t ban, ng\u1ee9a.<\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"width: 72.7336%;height: 21px\">Th\u1eadn v\u00e0 ti\u1ebft ni\u1ec7u: Gi\u1eef mu\u1ed1i v\u00e0 n\u01b0\u1edbc, t\u0103ng kali huy\u1ebft<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>C\u00e1c thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid kh\u00e1c: kh\u00f4ng d\u00f9ng c\u00f9ng v\u1edbi meloxicam v\u00ec l\u00e0m t\u0103ng nguy c\u01a1 lo\u00e9t d\u1ea1 d\u00e0y &#8211; t\u00e1 tr\u00e0ng v\u00e0 ch\u1ea3y m\u00e1u.<\/p>\n<p>Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u d\u1ea1ng u\u1ed1ng, heparin, ticlodipin, ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u, thu\u1ed1c l\u00e0m tan huy\u1ebft kh\u1ed1i: nguy c\u01a1 ch\u1ea3y m\u00e1u t\u0103ng khi d\u00f9ng c\u00f9ng, do v\u1eady tr\u00e1nh ph\u1ed1i h\u1ee3p.<\/p>\n<p>Lithi: n\u1ed3ng \u0111\u1ed9 lithi trong m\u00e1u t\u0103ng khi ph\u1ed1i h\u1ee3p v\u1edbi Meloxicam, do v\u1eady trong qu\u00e1 tr\u00ecnh d\u00f9ng k\u1ebft h\u1ee3p thu\u1ed1c v\u1edbi nhau, c\u1ea7n ph\u1ea3i theo d\u00f5i n\u1ed3ng \u0111\u1ed9 lithi trong m\u00e1u.<\/p>\n<p>\u0110\u1ed9c t\u00ednh c\u1ee7a methotrexat tr\u00ean h\u1ec7 th\u1ed1ng huy\u1ebft h\u1ecdc t\u0103ng khi d\u00f9ng c\u00f9ng Meloxicam.<\/p>\n<p>V\u00f2ng tr\u00e1nh thai: gi\u1ea3m hi\u1ec7u qu\u1ea3 tr\u00e1nh thai gi\u1ea3m khi d\u00f9ng c\u00f9ng Meloxicam.<\/p>\n<p>Thu\u1ed1c l\u1ee3i ni\u1ec7u: nguy c\u01a1 suy th\u1eadn c\u1ea5p \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb m\u1ea5t n\u01b0\u1edbc c\u00f3 th\u1ec3 t\u0103ng khi d\u00f9ng c\u00f9ng. N\u1ebfu d\u00f9ng ph\u1ed1i h\u1ee3p, ph\u1ea3i b\u1ed3i ph\u1ee5 \u0111\u1ee7 n\u01b0\u1edbc cho ng\u01b0\u1eddi b\u1ec7nh v\u00e0 ph\u1ea3i theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn.<\/p>\n<p>Thu\u1ed1c ch\u1ed1ng t\u0103ng huy\u1ebft \u00e1p nh\u01b0: Meloxicam l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng gi\u00e3n m\u1ea1ch, h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a c\u00e1c thu\u1ed1c ph\u1ed1i h\u1ee3p.<br \/>\nCholestyramin: Cholestyramin l\u00e0m gi\u1ea3m h\u1ea5p thu, t\u0103ng th\u1ea3i tr\u1eeb meloxicam.<\/p>\n<p>Warfarin: Meloxicam c\u00f3 th\u1ec3 l\u00e0m t\u0103ng qu\u00e1 tr\u00ecnh ch\u1ea3y m\u00e1u, do v\u1eady c\u1ea7n ph\u1ea3i theo d\u00f5i th\u1eddi gian ch\u1ea3y m\u00e1u do d\u00f9ng k\u00e8m.<\/p>\n<p>Meloxicam l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng l\u1ee3i ni\u1ec7u c\u1ee7a furosemid, nh\u00f3m thiazid.<\/p>\n<p>Thu\u1ed1c \u1ee9c ch\u1ebf calcineurin: NSAIDs l\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh tr\u00ean th\u1eadn. Do v\u1eady, c\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn khi ph\u1ed1i h\u1ee3p, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf ng\u01b0\u1eddi cao tu\u1ed5i.<\/p>\n<p>Corticosteroid: S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u ho\u1eb7c lo\u00e9t \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n<p>Thu\u1ed1c \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu ch\u1ecdn l\u1ecdc serotonin: T\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n<p>Pemetrexed: b\u1ec7nh nh\u00e2n c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin t\u1eeb 45 &#8211; 79 mL\/ ph\u00fat, n\u00ean ng\u1eebng d\u00f9ng meloxicam 5 ng\u00e0y tr\u01b0\u1edbc khi d\u00f9ng Pemetrexed. N\u1ebfu ph\u1ed1i h\u1ee3p 2 thu\u1ed1c th\u00ec n\u00ean theo d\u00f5i c\u1ea9n th\u1eadn t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n suy t\u1ee7y v\u00e0 tr\u00ean \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. B\u1ec7nh nh\u00e2n c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin &lt; 45 mL\/ ph\u00fat kh\u00f4ng ph\u1ed1i h\u1ee3p meloxicam v\u00e0 pemetrexed.<\/p>\n<p>Thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft \u0111\u01b0\u1eddng u\u1ed1ng: c\u00f3 th\u1ec3 t\u0103ng n\u1ed3ng \u0111\u1ed9 huy\u1ebft t\u01b0\u01a1ng c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y v\u00e0 meloxicam. Theo d\u00f5i h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng meloxicam v\u00e0 sulfonyl ure.<\/p>\n<p>Kh\u00f4ng d\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf CYP2C9.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng chung v\u1edbi ch\u1ea5t \u1ee9c ch\u1ebf CYP3A4 ho\u1eb7c thu\u1ed1c chuy\u1ec3n h\u00f3a b\u1edfi CYP3A4.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai<\/li>\n<\/ul>\n<p>Meloxicam l\u00e0m t\u0103ng nguy c\u01a1 \u0111\u00f3ng \u1ed1ng \u0111\u1ed9ng m\u1ea1ch s\u1edbm \u1edf thai nhi trong 3 th\u00e1ng cu\u1ed1i thai k\u1ef3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh meloxicam \u1edf ph\u1ee5 n\u1eef mang thai.<\/p>\n<ul>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa<\/li>\n<\/ul>\n<p>Kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c cho ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa, ng\u1eebng cho con b\u00fa n\u1ebfu ph\u1ea3i d\u00f9ng thu\u1ed1c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng: bu\u1ed3n ng\u1ee7, h\u00f4n m\u00ea, n\u00f4n, bu\u1ed3n n\u00f4n v\u00e0 \u0111au v\u00f9ng th\u01b0\u1ee3ng v\u1ecb, ch\u1ea3y m\u00e1u ti\u00eau h\u00f3a, suy th\u1eadn c\u1ea5p, t\u0103ng huy\u1ebft \u00e1p, suy h\u00f4 h\u1ea5p v\u00e0 h\u00f4n m\u00ea.<\/p>\n<p>X\u1eed tr\u00ed:\u00a0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3, c\u00e2n nh\u1eafc g\u00e2y n\u00f4n v\u00e0 d\u00f9ng than ho\u1ea1t, t\u1ea9y x\u1ed5. U\u1ed1ng cholestyramin c\u00f3 th\u1ec3 c\u00f3 \u00edch khi qu\u00e1 li\u1ec1u meloxicam.<\/p>\n<h3>T\u00e1c \u0111\u1ed9ng tr\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7 \u1ea3nh h\u01b0\u1edfng l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h2>Thu\u1ed1c Coxnis gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Coxnis<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/melobic\/\">Melobic<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m v\u00e0 sinh h\u1ecdc y t\u1ebf, ch\u1ee9a meloxicam v\u1edbi h\u00e0m l\u01b0\u1ee3ng 7,5mg. Thu\u1ed1c d\u00f9ng \u0111i\u1ec1u tr\u1ecb vi\u00eam x\u01b0\u01a1ng kh\u1edbp m\u1ea1n t\u00ednh nh\u01b0: tho\u00e1i h\u00f3a kh\u1edbp, h\u01b0 kh\u1edbp, vi\u00eam \u0111au x\u01b0\u01a1ng kh\u1edbp m\u1ea1n t\u00ednh, vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp, th\u1ea5p kh\u1edbp. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n, trong vi\u00eam \u0111au x\u01b0\u01a1ng kh\u1edbp b\u1ea1n c\u00f3 th\u1ec3 u\u1ed1ng 1 vi\u00ean\/ng\u00e0y. Thu\u1ed1c c\u00f3 gi\u00e1 28.500 \u0111\u1ed3ng\/ 1 h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/trosicam\/\">Trosicam<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Alpex Pharma SA., Th\u1ee5y S\u0129, ch\u1ee9a Meloxicam v\u1edbi h\u00e0m l\u01b0\u1ee3ng 15mg d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111au do vi\u00eam x\u01b0\u01a1ng kh\u1edbp m\u00e3n t\u00ednh g\u00e2y ra. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean n\u00e9n ph\u00e2n t\u00e1n t\u1ea1i mi\u1ec7ng v\u00e0 c\u00f3 gi\u00e1 kho\u1ea3ng 236.700 \u0111\u1ed3ng\/ 1 h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<\/p>\n<h2>T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Coxnis?<\/h2>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 50%;text-align: center\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 50%;text-align: center\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">Meloxicam l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID) \u0111\u01b0\u1eddng u\u1ed1ng t\u01b0\u01a1ng \u0111\u1ed1i m\u1edbi \u0111\u01b0\u1ee3c ph\u00ea duy\u1ec7t \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb vi\u00eam x\u01b0\u01a1ng kh\u1edbp \u1edf Hoa K\u1ef3.<\/td>\n<td style=\"width: 50%\">Meloxicam kh\u00f4ng an to\u00e0n khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 cho con b\u00fa.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">So v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf kh\u00f4ng ch\u1ecdn l\u1ecdc COX, Meloxicam \u00edt c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean ti\u00eau h\u00f3a h\u01a1n.<\/td>\n<td style=\"width: 50%\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n r\u1ea5t th\u01b0\u1eddng g\u1eb7p tr\u00ean ti\u00eau h\u00f3a: Kh\u00f3 ti\u00eau, n\u00f4n, bu\u1ed3n n\u00f4n, t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">Trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng c\u1ee7a meloxicam trong \u0111i\u1ec1u tr\u1ecb vi\u00eam x\u01b0\u01a1ng kh\u1edbp, ng\u01b0\u1eddi ta th\u1ea5y r\u1eb1ng n\u00f3 c\u00f3 hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi piroxicam, diclofenac v\u00e0 naproxen v\u1edbi \u00edt tri\u1ec7u ch\u1ee9ng ti\u00eau h\u00f3a l\u00e2m s\u00e0ng h\u01a1n v\u00e0 \u00edt th\u1ee7ng, t\u1eafc ngh\u1ebdn v\u00e0 ch\u1ea3y m\u00e1u h\u01a1n.<\/td>\n<td style=\"width: 50%\"><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">Gi\u00e1 th\u00e0nh s\u1ea3n ph\u1ea9m kh\u00e1 r\u1ebb.<\/td>\n<td style=\"width: 50%\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u00e1c gi\u1ea3 Roy Fleischmann v\u00e0 c\u1ed9ng s\u1ef1 (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 10 n\u0103m 2002). <em>Meloxicam<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 21 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12387696\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/12387696\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 O A Shavlovskayai v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh n\u0103m 2022). <em>Meloxicam clinical effects<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 21 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35175701\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35175701\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 D T\u00fcrck\u00a0 v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 03 n\u0103m 1997). <em>Clinical pharmacokinetics of meloxicam<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 21 th\u00e1ng 10 n\u0103m 2023, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9105543\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/9105543\/<\/a><\/li>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i b\u1ea3n PDF <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2023\/10\/Coxnis-vnras.pdf\">T\u1ea0I \u0110\u00c2Y<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Coxnis ch\u1ee9a Meloxicam 7,5mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb b\u1ec7nh vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp, tho\u00e1i h\u00f3a kh\u1edbp, b\u1ec7nh kh\u1edbp m\u1ea1n t\u00ednh kh\u00e1c v\u00e0 vi\u00eam kh\u1edbp \u1edf thanh thi\u1ebfu ni\u00ean<\/p>\n","protected":false},"author":490,"featured_media":50375,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-50374","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/50374","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=50374"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/50375"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=50374"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=50374"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=50374"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}