{"id":50029,"date":"2023-10-19T14:02:55","date_gmt":"2023-10-19T07:02:55","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=50029"},"modified":"2025-07-24T14:00:09","modified_gmt":"2025-07-24T07:00:09","slug":"zarsitex","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/zarsitex\/","title":{"rendered":"Zarsitex"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/zarsitex\/\">Zarsitex<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-21993-14<\/strong><\/p>\n<h2>Zarsitex l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean <strong>Zarsitex<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: <strong>Venlafaxin<\/strong> (d\u01b0\u1edbi d\u1ea1ng Venlafaxin HCl) 75mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang c\u1ee9ng.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-21993-14.<br \/>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<br \/>\nXu\u1ea5t x\u1ee9: Vi\u1ec7t Nam.<\/p>\n<h2>Thu\u1ed1c Zarsitex c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Venlafaxin l\u00e0 m\u1ed9t d\u1eabn xu\u1ea5t c\u1ee7a phenylethylamin, t\u00e1c \u0111\u1ed9ng \u1ee9c ch\u1ebf thu h\u1ed3i ch\u1ecdn l\u1ecdc serotonin v\u00e0 norepinephrin, c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng lo \u00e2u v\u00e0 ch\u1ed1ng tr\u1ea7m c\u1ea3m. C\u01a1 ch\u1ebf ch\u1ed1ng lo \u00e2u v\u00e0 tr\u1ea7m c\u1ea3m ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft r\u00f5, tuy nhi\u00ean n\u00f3 c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c t\u0103ng c\u01b0\u1eddng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a ch\u1ea5t d\u1eabn truy\u1ec1n th\u1ea7n kinh trong h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng.<\/p>\n<p>Venlafaxin v\u00e0 O-desmethylvenlafaxin (ODV) &#8211; ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh c\u1ee7a n\u00f3 \u1ee9c ch\u1ebf m\u1ea1nh s\u1ef1 thu h\u1ed3i serotonin v\u00e0 norepinephrin th\u1ea7n kinh, tuy nhi\u00ean \u1ee9c ch\u1ebf y\u1ebfu s\u1ef1 thu h\u1ed3i dopamin.<\/p>\n<p>Trong in vitro, venlafaxin v\u00e0 ODV kh\u00f4ng c\u00f3 \u00e1i l\u1ef1c \u0111\u00e1ng k\u1ec3 \u0111\u1ed1i v\u1edbi th\u1ee5 th\u1ec3 H1 histaminergic, cholinergic muscarinic hay anpha 1 adrenergic.<\/p>\n<h3>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu<\/li>\n<\/ul>\n<p>Venlafaxin \u0111\u01b0\u1ee3c h\u1ea5p th\u1ee5 d\u1ec5 d\u00e0ng qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. 2 &#8211; 4 gi\u1edd sau khi u\u1ed1ng, thu\u1ed1c \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<ul>\n<li>Chuy\u1ec3n h\u00f3a<\/li>\n<\/ul>\n<p>Ph\u1ea7n l\u1edbn sau khi u\u1ed1ng, thu\u1ed1c chuy\u1ec3n h\u00f3a b\u01b0\u1edbc \u0111\u1ea7u t\u1ea1o th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh O-desmethylvenlafaxin qua trung gian cytochrom P450 CYP2D6. Tham gia v\u00e0o qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a venlafaxin c\u00f2n c\u00f3 isoenzym CYP3A4 c\u0169ng. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00e1c bao g\u1ed3m O-didesmethylvenlafaxin v\u00e0 N-desmethylvenlafaxin.<\/p>\n<ul>\n<li>Ph\u00e2n b\u1ed1<\/li>\n<\/ul>\n<p>Kh\u1ea3 n\u0103ng li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng c\u1ee7a venlafaxin l\u00e0 27% v\u00e0 O-desmethylvenlafaxin l\u00e0 30%.<br \/>\n\u0110\u00e3 th\u1ea5y s\u1ef1 xu\u1ea5t hi\u1ec7n c\u1ee7a Venlafaxin v\u00e0 O-desmethyl-venlafaxin trong n\u01b0\u1edbc \u1ed1i, m\u00e1u d\u00e2y r\u1ed1n v\u00e0 \u0111i qua \u0111\u01b0\u1ee3c s\u1eefa m\u1eb9.<\/p>\n<ul>\n<li>Th\u1ea3i tr\u1eeb<\/li>\n<\/ul>\n<p>Th\u1eddi gian b\u1ea3n th\u00e1i trung b\u00ecnh c\u1ee7a venlafaxin v\u00e0 O-desmethylvenlafaxin l\u1ea7n l\u01b0\u1ee3t l\u00e0 5 v\u00e0 11 gi\u1edd.<br \/>\nPh\u1ea7n l\u1edbn venlafaxin \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb d\u01b0\u1edbi d\u1ea1ng c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a ho\u1eb7c d\u1ea1ng t\u1ef1 do ho\u1eb7c d\u01b0\u1edbi h\u00ecnh th\u1ee9c li\u00ean h\u1ee3p qua n\u01b0\u1edbc ti\u1ec3u, c\u00f2n l\u1ea1i kho\u1ea3ng 2% \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua ph\u00e2n.<\/p>\n<h2>Thu\u1ed1c Zarsitex \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n n\u1ed9i v\u00e0 ngo\u1ea1i tr\u00fa tr\u1ea7m c\u1ea3m, bao g\u1ed3m tr\u1ea7m c\u1ea3m k\u00e8m theo lo l\u1eafng.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Zarsitex<\/h2>\n<p>Tr\u1ea7m c\u1ea3m: li\u1ec1u ban \u0111\u1ea7u 1 vi\u00ean chia 2 &#8211; 3 l\u1ea7n\/ ng\u00e0y, trong v\u00f2ng 3 &#8211; 4 ng\u00e0y. Sau \u0111\u00f3 t\u0103ng li\u1ec1u l\u00ean 1 vi\u00ean\/ ng\u00e0y. Sau v\u00e0i tu\u1ea7n li\u1ec1u c\u00f3 th\u1ec3 t\u0103ng l\u00ean \u0111\u1ebfn 2 vi\u00ean\/ ng\u00e0y n\u1ebfu c\u1ea7n. Li\u1ec1u t\u1ed1i \u0111a l\u00e0 375 mg. M\u1ed7i l\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u c\u00f3 th\u1ec3 t\u0103ng t\u1ed1i \u0111a 1 vi\u00ean trong th\u1eddi gian 2 \u2013 4 ng\u00e0y.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy th\u1eadn ho\u1eb7c suy gan:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 ch\u1ec9 s\u1ed1 l\u1ecdc c\u1ea7u th\u1ea7n (GFR) &lt; 30 ml\/ph\u00fat th\u00ec gi\u1ea3m c\u00f2n 1\/2 li\u1ec1u h\u00e0ng ng\u00e0y, c\u00f3 th\u1ec3 d\u00f9ng to\u00e0n b\u1ed9 li\u1ec1u m\u1ed9t l\u1ea7n cho c\u1ea3 ng\u00e0y. Ng\u01b0\u1eddi ph\u1ea3i th\u1ea9m t\u00e1ch m\u00e1u n\u00ean ng\u1eebng d\u00f9ng venlafaxin cho cho t\u1edbi khi ho\u00e0n th\u00e0nh vi\u1ec7c \u0111i\u1ec1u tr\u1ecb.<\/li>\n<li>B\u1ec7nh nh\u00e2n b\u1ecb suy gan m\u1ee9c \u0111\u1ed9 trung b\u00ecnh (th\u1eddi gian prothrombin t\u1eeb 14 &#8211; 18 gi\u00e2y) th\u00ec gi\u1ea3m c\u00f2n 1\/2 li\u1ec1u. Ng\u01b0\u1eddi b\u1ecb suy gan m\u1ee9c \u0111\u1ed9 n\u1eb7ng h\u01a1n c\u1ea7n gi\u1ea3m li\u1ec1u xu\u1ed1ng th\u1ea5p h\u01a1n n\u1eefa.<\/li>\n<\/ul>\n<p>Ng\u01b0\u1eddi gi\u00e0: Kh\u00f4ng c\u1ea7n gi\u1ea3m li\u1ec1u, nh\u01b0ng v\u1eabn c\u1ea7n th\u1eadn tr\u1ecdng khi \u0111i\u1ec1u tr\u1ecb cho ng\u01b0\u1eddi gi\u00e0, \u0111\u1eb7c bi\u1ec7t ch\u00fa \u00fd khi t\u0103ng li\u1ec1u.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Zarsitex trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>M\u1eabn c\u1ea3m v\u1edbi ho\u1ea1t ch\u1ea5t ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>\u0110ang d\u00f9ng ch\u1ea5t \u1ee9c ch\u1ebf monoamin oxidase (IMAO).<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 tim m\u1ea1ch cao ( t\u0103ng huy\u1ebft \u00e1p kh\u00f4ng ki\u1ec3m so\u00e1t, lo\u1ea1n nh\u1ecbp th\u1ea5t,&#8230;).<\/li>\n<li>Tr\u1ebb em &lt; 18 tu\u1ed5i.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Zarsitex<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Ch\u00fa \u00fd nguy c\u01a1 t\u1ef1 t\u1eed \u1edf b\u1ec7nh nh\u00e2n tr\u1ea7m c\u1ea3m. D\u00f9ng venlafaxin v\u1edbi li\u1ec1u th\u1ea5p \u0111\u1ec3 ki\u1ec3m so\u00e1t t\u1ed1t b\u1ec7nh nh\u00e2n v\u00e0 gi\u1ea3m nguy c\u01a1 qu\u00e1 li\u1ec1u.<\/p>\n<p>C\u00f3 th\u1ec3 x\u1ea3y ra t\u01b0\u01a1ng t\u00e1c gi\u1eefa Venlafaxin v\u1edbi c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf monoamin oxidase (IMAO).<\/p>\n<p>Sau khi ng\u1eebng d\u00f9ng m\u1ed9t thu\u1ed1c IMAO v\u00e0 b\u1eaft \u0111\u1ea7u d\u00f9ng m\u1ed9t thu\u1ed1c IMAO ngay sau khi ng\u1eebng d\u00f9ng venlafaxin, \u0111\u00e3 ghi nh\u1eadn c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1ed3m c\u00f3 to\u00e1t m\u1ed3 h\u00f4i, bu\u1ed3n n\u00f4n, run r\u1ea9y, m\u00faa gi\u1eadt, n\u00f4n, ch\u00f3ng m\u1eb7t, n\u00f3ng \u0111\u1ecf b\u1eebng, s\u1ed1t cao v\u1edbi c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m gi\u1ed1ng nh\u01b0 h\u1ed9i ch\u1ee9ng th\u1ea7n kinh \u00e1c t\u00ednh, co gi\u1eadt v\u00e0 ch\u1ebft. C\u00e1c ph\u1ea3n \u1ee9ng n\u00e0y \u0111\u01b0\u1ee3c ghi nh\u1eadn khi d\u00f9ng \u0111\u1ed3ng th\u1eddi ho\u1eb7c li\u00ean ti\u1ebfp c\u00e1c thu\u1ed1c IMAO v\u00e0 c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m kh\u00e1c c\u00f3 \u0111\u1eb7c t\u00ednh d\u01b0\u1ee3c l\u00fd gi\u1ed1ng nh\u01b0 venlafaxin. V\u00ec v\u1eady, kh\u00f4ng d\u00f9ng ph\u1ed1i h\u1ee3p venlafaxin v\u1edbi m\u1ed9t thu\u1ed1c IMAO ho\u1eb7c trong v\u00f2ng 14 ng\u00e0y sau khi d\u1eebng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng IMAO. Sau khi ng\u1eebng venlafaxin \u00edt nh\u1ea5t 7 ng\u00e0y m\u1edbi \u0111\u01b0\u1ee3c d\u00f9ng IMAO.<\/p>\n<p>Khi d\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu serotonin nhanh v\u00e0 ch\u1ecdn l\u1ecdc v\u1edbi IMAO \u0111\u00e3 g\u1eb7p ph\u1ea3n \u1ee9ng t\u0103ng th\u00e2n nhi\u1ec7t, kh\u00f4ng \u1ed5n \u0111\u1ecbnh th\u1ea7n kinh t\u1ef1 \u0111\u1ed9ng, co c\u1ee9ng, m\u00faa gi\u1eadt, thay \u0111\u1ed5i tr\u1ea1ng th\u00e1i tinh th\u1ea7n bao g\u1ed3m k\u00edch \u0111\u1ed9ng qu\u00e1 m\u1ee9c d\u1eabn t\u1edbi m\u00ea s\u1ea3ng, h\u00f4n m\u00ea, v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng gi\u1ed1ng nh\u01b0 h\u1ed9i ch\u1ee9ng th\u1ea7n kinh \u00e1c t\u00ednh.<\/p>\n<p>D\u00f9ng \u0111\u1ed3ng th\u1eddi thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m 3 v\u00f2ng v\u00e0 IMAO c\u00f3 th\u1ec3 g\u00e2y t\u0103ng th\u00e2n nhi\u1ec7t n\u1eb7ng v\u00e0 \u0111\u1ed9ng kinh, \u0111\u00f4i khi t\u1eed vong.<\/p>\n<p>D\u1eebng Venlafaxin:<\/p>\n<p>M\u1eb7c d\u00f9 c\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng v\u1ec1 ng\u1eebng thu\u1ed1c kh\u00f4ng th\u1ea5y c\u00f3 xu\u1ea5t hi\u1ec7n tri\u1ec7u ch\u1ee9ng g\u00ec, nh\u01b0ng \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n v\u1eabn n\u00ean gi\u1ea3m d\u1ea7n li\u1ec1u khi ng\u1eebng thu\u1ed1c sau th\u1eddi gian \u0111i\u1ec1u tr\u1ecb tr\u00ean 1 tu\u1ea7n. Gi\u1ea3m d\u1ea7n li\u1ec1u trong v\u00f2ng 1 tu\u1ea7n \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n d\u00f9ng venlafaxin t\u1eeb 6 tu\u1ea7n tr\u1edf l\u00ean.<\/p>\n<p>\u0110\u1ec3 xa t\u1ea7m tay tr\u1ebb em<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>T\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p nh\u1ea5t li\u00ean quan \u0111\u1ebfn r\u1ed1i lo\u1ea1n th\u1ea7n kinh (kh\u00f4 mi\u1ec7ng, ch\u00f3ng m\u1eb7t, m\u1ea5t ng\u1ee7, ng\u1ee7 g\u00e0); r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a (t\u00e1o b\u00f3n, ch\u00e1n \u0103n, bu\u1ed3n n\u00f4n); r\u1ed1i lo\u1ea1n xu\u1ea5t tinh; ra nhi\u1ec1u m\u1ed3 h\u00f4i; suy nh\u01b0\u1ee3c.<\/p>\n<p>M\u1ee9c \u0111\u1ed9 th\u01b0\u1eddng xuy\u00ean c\u1ee7a c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 li\u00ean quan \u0111\u1ebfn li\u1ec1u d\u00f9ng. N\u00f3i chung, c\u00e1c ph\u1ea3n \u1ee9ng ph\u1ee5 n\u00e0y gi\u1ea3m \u0111i khi d\u00f9ng d\u00e0i ng\u00e0y.<\/p>\n<p>Th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u1ec1 c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng thu\u1ed1c.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf monoamin oxidase: Kh\u00f4ng d\u00f9ng \u0111\u1ed3ng th\u1eddi venlafaxin.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng venlafaxin \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c t\u00e1c d\u1ee5ng tr\u00ean th\u1ea7n kinh trung \u01b0\u01a1ng kh\u00e1c.<\/p>\n<p>Cimetidin l\u00e0m chuy\u1ec3n h\u00f3a b\u01b0\u1edbc \u0111\u1ea7u c\u1ee7a venlafaxin b\u1ecb \u1ee9c ch\u1ebf, t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd t\u1ed5ng h\u1ee3p c\u1ee7a O-desmethyl venlafaxin v\u00e0 venlafaxin ch\u1ec9 t\u0103ng r\u1ea5t nh\u1eb9.<\/p>\n<p>Ch\u01b0a r\u00f5 t\u01b0\u01a1ng t\u00e1c khi d\u00f9ng venlafaxin c\u00f9ng v\u1edbi cimetidin \u1edf ng\u01b0\u1eddi gi\u00e0 v\u00e0 b\u1ec7nh nh\u00e2n suy gan, v\u00ec v\u1eady c\u1ea7n theo d\u00f5i l\u00e2m s\u00e0ng \u0111\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y.<\/p>\n<p>C\u1ea7n \u0111\u00e1nh gi\u00e1 l\u1ea1i t\u01b0\u01a1ng t\u00e1c trong vi\u1ec7c d\u00f9ng venlafaxin \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng t\u0103ng huy\u1ebft \u00e1p hay c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef mang thai<\/li>\n<\/ul>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 \u0111\u1ed9 an to\u00e0n c\u1ee7a thu\u1ed1c tr\u00ean ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa. Kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c n\u00e0y trong thai k\u1ef3, tr\u1eeb khi l\u1ee3i \u00edch l\u1edbn h\u01a1n nguy c\u01a1 c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i. Th\u00f4ng b\u00e1o v\u1edbi b\u00e1c s\u0129 n\u1ebfu \u0111ang mang thai ho\u1eb7c d\u1ef1 \u0111\u1ecbnh mang thai trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb.<\/p>\n<ul>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa<\/li>\n<\/ul>\n<p>Kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa v\u00ec ch\u01b0a bi\u1ebft thu\u1ed1c c\u00f3 qua \u0111\u01b0\u1ee3c s\u1eefa m\u1eb9 hay kh\u00f4ng.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u venlafaxin, d\u00f9ng \u0111\u01a1n \u0111\u1ed9c c\u0169ng nh\u01b0 c\u00f9ng v\u1edbi thu\u1ed1c kh\u00e1c v\u00e0\/ ho\u1eb7c r\u01b0\u1ee3u \u0111\u00e3 c\u00f3 thay \u0111\u1ed5i \u0111i\u1ec7n t\u00e2m \u0111\u1ed3, ch\u1eadm nh\u1ecbp tim, t\u0103ng nh\u1ecbp t\u00e2m th\u1ea5t v\u00e0 sinap, \u0111\u1ed9ng kinh.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb:<\/p>\n<ul>\n<li>Cung c\u1ea5p \u0111\u1ee7 oxy v\u00e0 th\u00f4ng kh\u00ed \u0111\u1ea7y \u0111\u1ee7 c\u00f9ng v\u1edbi ki\u1ec3m tra nh\u1ecbp tim v\u00e0 c\u00e1c d\u1ea5u hi\u1ec7u s\u1ed1ng.<\/li>\n<li>K\u1ebft h\u1ee3p \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 v\u1edbi \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, d\u00f9ng than ho\u1ea1t, g\u00e2y n\u00f4n hay r\u1eeda d\u1ea1 d\u00e0y.<\/li>\n<li>D\u00f9ng th\u1ea9m t\u00e1ch m\u00e1u kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng.<\/li>\n<\/ul>\n<h3>T\u00e1c \u0111\u1ed9ng tr\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c khi d\u00f9ng thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m.<\/p>\n<h2>Thu\u1ed1c Zarsitex gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Zarsitex<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/venlafaxine-stada\/\">Venlafaxine Stada<\/a> c\u0169ng \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty li\u00ean doanh TNHH Stada-Vi\u1ec7t Nam, ch\u1ee9a Venlafaxin v\u1edbi h\u00e0m l\u01b0\u1ee3ng 37.5 mg\/vi\u00ean. Thu\u1ed1c d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb v\u00e0 ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t c\u00e1c c\u01a1n tr\u1ea7m c\u1ea3m n\u1eb7ng, \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n lo \u00e2u lan t\u1ecfa, r\u1ed1i lo\u1ea1n lo \u00e2u x\u00e3 h\u1ed9i. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean nang c\u1ee9ng. Li\u1ec1u kh\u1edfi \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m n\u1eb7ng l\u00e0 m\u1ed7i ng\u00e0y 1 l\u1ea7n, m\u1ed7i l\u1ea7n 75 mg. Thu\u1ed1c c\u00f3 gi\u00e1 320.000 \u0111\u1ed3ng\/ 1 h\u1ed9p c\u00f3 ch\u1ee9a 2 v\u1ec9 x 14 vi\u00ean.<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/dobdia-30mg\/\">Dobdia<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m SAVI ch\u1ee9a Mirtazapin v\u1edbi h\u00e0m l\u01b0\u1ee3ng 30mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n tr\u1ea7m c\u1ea3m n\u1eb7ng \u0111\u01a1n c\u1ef1c. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean n\u00e9n bao phim. Li\u1ec1u u\u1ed1ng kh\u1edfi \u0111\u1ea7u l\u00e0 15 \u2013 30mg\/l\u1ea7n\/ng\u00e0y.<\/p>\n<h2>T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Zarsitex?<\/h2>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 56.1367%;text-align: center\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 43.8633%;text-align: center\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 56.1367%\">Venlafaxine \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb v\u00e0 ki\u1ec3m so\u00e1t c\u00e1c tri\u1ec7u ch\u1ee9ng tr\u1ea7m c\u1ea3m, r\u1ed1i lo\u1ea1n lo \u00e2u x\u00e3 h\u1ed9i v\u00e0 ch\u1ee9ng m\u1ea5t tr\u01b0\u01a1ng l\u1ef1c.<\/td>\n<td style=\"width: 43.8633%\">C\u1ea7n ph\u1ea3i hi\u1ec7u ch\u1ec9nh li\u1ec1u \u1edf ng\u01b0\u1eddi suy gi\u1ea3m ch\u1ee9c n\u0103ng gan, th\u1eadn.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 56.1367%\">Venlafaxine \u0111\u01b0\u1ee3c dung n\u1ea1p t\u1ed1t, c\u00f3 \u00edt t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1ng cholinergic v\u00e0 h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng h\u01a1n so v\u1edbi thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m ba v\u00f2ng.<\/td>\n<td style=\"width: 43.8633%\">Venlafaxine ch\u1ec9 \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n cho ng\u01b0\u1eddi t\u1eeb 18 tu\u1ed5i tr\u1edf l\u00ean v\u00e0 kh\u00f4ng n\u00ean d\u00f9ng cho tr\u1ebb em d\u01b0\u1edbi 18 tu\u1ed5i.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 56.1367%\">Thi\u1ebft k\u1ebf d\u1ea1ng vi\u00ean nang c\u1ee9ng ti\u1ec7n d\u00f9ng, d\u1ec5 d\u00e0ng b\u1ea3o qu\u1ea3n v\u00e0 mang theo ng\u01b0\u1eddi.<\/td>\n<td style=\"width: 43.8633%\"><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 56.1367%\">Zarsitex \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa &#8211; c\u00f4ng ty n\u1eb1m trong top 5 c\u00f4ng ty D\u01b0\u1ee3c ph\u1ea9m h\u00e0ng \u0111\u1ea7u t\u1ea1i Vi\u1ec7t Nam v\u1edbi nh\u00e2n vi\u00ean c\u00f3 chuy\u00ean m\u00f4n k\u1ef9 thu\u1eadt cao v\u00e0 d\u00e0y d\u1eb7n kinh nghi\u1ec7m.<\/td>\n<td style=\"width: 43.8633%\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>Chuy\u00ean gia c\u1ee7a Pubmed (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 10 th\u00e1ng 10 n\u0103m 2022). <em>Venlafaxine<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 19 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535363\/\" rel=\"noopener\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK535363\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 Michael Bauer v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 04 n\u0103m 2009). <em>The effect of venlafaxine compared with other antidepressants and placebo in the treatment of major depression: a meta-analysis<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 19 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19165525\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/19165525\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3 S M Holliday v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 02 n\u0103m 1995). <em>Venlafaxine. A review of its pharmacology and therapeutic potential in depression<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 19 th\u00e1ng 10 n\u0103m 2023, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7729333\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/7729333\/<\/a><\/li>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i b\u1ea3n PDF <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2023\/10\/Zarsitex-vnras.pdf\">T\u1ea0I \u0110\u00c2Y<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Zarsitex ch\u1ee9a ho\u1ea1t ch\u1ea5t Venlafaxin (d\u01b0\u1edbi d\u1ea1ng Venlafaxin HCl) v\u1edbi h\u00e0m l\u01b0\u1ee3ng 75mg d\u00f9ng \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n n\u1ed9i v\u00e0 ngo\u1ea1i tr\u00fa tr\u1ea7m c\u1ea3m, bao g\u1ed3m tr\u1ea7m c\u1ea3m k\u00e8m theo lo l\u1eafng<\/p>\n","protected":false},"author":490,"featured_media":50030,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-50029","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/50029","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=50029"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/50030"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=50029"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=50029"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=50029"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}