{"id":49526,"date":"2023-10-17T17:03:53","date_gmt":"2023-10-17T10:03:53","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=49526"},"modified":"2025-07-24T14:01:39","modified_gmt":"2025-07-24T07:01:39","slug":"cotrimoxazole-800-160","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/cotrimoxazole-800-160\/","title":{"rendered":"Cotrimoxazole 800\/160"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Cotrimoxazole 800\/160<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH LD Stellapharm – Chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-23966-15<\/strong><\/p>\n

Cotrimoxazole 800\/160 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Th\u00e0nh ph\u1ea7n<\/h3>\n
M\u1ed7i vi\u00ean Cotrimoxazole 800\/160<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n\n\n\n\n
Ho\u1ea1t ch\u1ea5t<\/td>\n T\u00e1 d\u01b0\u1ee3c<\/td>\n<\/tr>\n
Sulfamethoxazole 800 mg
\nTrimethoprim: 160 mg<\/td>\n V\u1eeba \u0111\u1ee7 1 vi\u00ean<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n.<\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: VD-23966-15.
\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.
\nXu\u1ea5t x\u1ee9:Vi\u1ec7t Nam.<\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Cotrimoxazole 800\/160<\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n
\n
Cotrimoxazole l\u00e0 m\u1ed9t h\u1ed7n h\u1ee3p g\u1ed3m hai ho\u1ea1t ch\u1ea5t: sulfamethoxazole ( 5 ph\u1ea7n) v\u00e0 trimethoprim (1 ph\u1ea7n).<\/li>\n
Sulfamethoxazole l\u00e0 m\u1ed9t sulfonamid, c\u00f3 t\u00e1c \u0111\u1ed9ng di\u1ec7t khu\u1ea9n do \u1ee9c ch\u1ebf c\u1ea1nh tranh giai \u0111o\u1ea1n t\u1ed5ng h\u1ee3p acid folic.
\nTrimethoprim l\u00e0 d\u1eabn xu\u1ea5t c\u1ee7a pyrimidin, ho\u1ea1t \u0111\u1ed9ng kh\u00e1ng khu\u1ea9n nh\u1edd \u1ee9c ch\u1ebf enzym dihydrofolat reductase.<\/li>\n
\u0110\u00e2y l\u00e0 hai giai \u0111o\u1ea1n li\u00ean ti\u1ebfp trong chuy\u1ec3n h\u00f3a acid folic, t\u1eeb \u0111\u00f3 \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p purin, thymidin v\u00e0 DNA c\u1ee7a vi khu\u1ea9n, s\u1ef1 \u1ee9c ch\u1ebf n\u1ed1i ti\u1ebfp n\u00e0y l\u00e0m cho vi khu\u1ea9n b\u1ecb ti\u00eau di\u1ec7t. Ngo\u00e0i ra, ph\u1ed1i h\u1ee3p Sulfamethoxazole v\u00e0 Trimethoprim gi\u00fap k\u00ecm h\u00e3m s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a vi khu\u1ea9n kh\u00e1ng thu\u1ed1c, thu\u1ed1c v\u1eabn c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i v\u1edbi vi khu\u1ea9n \u0111\u00e3 kh\u00e1ng t\u1eebng th\u00e0nh ph\u1ea7n ri\u00eang l\u1ebb.<\/li>\n
C\u00e1c vi sinh v\u1eadt nh\u1ea1y c\u1ea3m v\u1edbi thu\u1ed1c : E. coli, Morganella morganii, Klebsiella spp., S. pneumoniae, Proteus mirabilis, Enterobacter spp., P. vulgaris, H. influenzae, Proteus indol d\u01b0\u01a1ng t\u00ednh, Shigella sonnei, Pneumocystis carinii, Shigella flexneri, Plasmodium falciparum, Toxoplasma gondii.<\/li>\n
Thu\u1ed1c th\u01b0\u1eddng b\u1ecb kh\u00e1ng b\u1edfi c\u00e1c vi sinh v\u1eadt sau: vi khu\u1ea9n k\u1ef5 kh\u00ed (Anaerobes), Pseudomonas, n\u00e3o m\u00f4 c\u1ea7u (Meningococcus), Campylobacter, Enterococcus, l\u1eadu c\u1ea7u (Gonococcus), Mycoplasma.<\/li>\n
Trong in vitro, s\u1ef1 kh\u00e1ng cotrimoxazole di\u1ec5n ra ch\u1eadm h\u01a1n so v\u1edbi kh\u00e1ng t\u1eebng th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c. S\u1ef1 kh\u00e1ng n\u00e0y t\u0103ng c\u1ea3 \u1edf vi khu\u1ea9n Gram (+) v\u00e0 Gram (-). \u0110\u1ec1 kh\u00e1ng \u0111\u00e1ng k\u1ec3 \u1edf Enterobacter.<\/li>\n<\/ul>\n
D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n
\n
H\u1ea5p thu<\/li>\n<\/ul>\n
Cotrimoxazole h\u1ea5p thu t\u1ed1t v\u00e0 nhanh qua \u0111\u01b0\u1eddng u\u1ed1ng. Kho\u1ea3ng 1 – 4 gi\u1edd sau khi u\u1ed1ng li\u1ec1u \u0111\u01a1n cotrimoxazole 800\/160, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u1ee7a sulfamethoxazole kh\u00f4ng g\u1eafn k\u1ebft l\u00e0 40 – 60 mcg\/ml v\u00e0 trimethoprim \u0111\u1ea1t \u0111\u01b0\u1ee3c l\u00e0 1 – 2 mcg\/ml.<\/p>\n
\n
Ph\u00e2n b\u1ed1<\/li>\n<\/ul>\n
Cotrimoxazole ph\u00e2n b\u1ed1 tr\u1ea3i r\u1ed9ng trong m\u00f4 v\u00e0 d\u1ecbch c\u01a1 th\u1ec3 (n\u01b0\u1edbc b\u1ecdt, th\u1ee7y d\u1ecbch, d\u1ecbch tai gi\u1eefa, d\u1ecbch tuy\u1ebfn ti\u1ec1n li\u1ec7t, d\u1ecbch \u00e2m \u0111\u1ea1o, m\u1eadt v\u00e0 d\u1ecbch n\u00e3o t\u1ee7y), trong d\u1ecbch ti\u1ebft ph\u1ed5i t\u00ecm th\u1ea5y trimethoprim.
\nTh\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a trimethoprim l\u1edbn h\u01a1n c\u1ee7a sulfamethoxazole.
\nThu\u1ed1c d\u1ec5 d\u00e0ng qua nhau thai v\u00e0 s\u1eefa m\u1eb9.
\nKh\u1ea3 n\u0103ng g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng c\u1ee7a sulfamethoxazole kho\u1ea3ng 70% v\u00e0 trimethoprim l\u00e0 44%.<\/p>\n
\n
Chuy\u1ec3n h\u00f3a<\/li>\n<\/ul>\n
Thu\u1ed1c chuy\u1ec3n h\u00f3a qua gan.<\/p>\n
\n
Th\u1ea3i tr\u1eeb<\/li>\n<\/ul>\n
Ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh v\u1edbi ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng, th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a sulfamethoxazole l\u00e0 10 – 13 gi\u1edd v\u00e0 trimethoprim l\u00e0 8 – 11 gi\u1edd. Trong 24 gi\u1edd, c\u00f3 kho\u1ea3ng 45 – 70% sulfamethoxazole v\u00e0\u00a0 50 – 60% trimethoprim li\u1ec1u u\u1ed1ng \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u.<\/p>\n
Kho\u1ea3ng 20% sulfamethoxazole v\u00e0 80% trimethoprim \u1edf d\u1ea1ng kh\u00f4ng \u0111\u1ed5i th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u. M\u1ed9t l\u01b0\u1ee3ng nh\u1ecf trimethoprim b\u00e0i ti\u1ebft qua m\u1eadt v\u00e0 ph\u00e2n.<\/p>\n
Thu\u1ed1c Cotrimoxazole 800\/160 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n
\n
Vi\u00eam tai gi\u1eefa c\u1ea5p.<\/li>\n
Nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u m\u1ea1n t\u00ednh ho\u1eb7c t\u00e1i ph\u00e1t ho\u1eb7c vi\u00eam ti\u1ec1n li\u1ec7t tuy\u1ebfn.<\/li>\n
Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p.<\/li>\n
Vi\u00eam ph\u1ed5i do Pneumocystis jiroveci (Pneumocystis carinii).<\/li>\n
B\u1ec7nh brucella, b\u1ec7nh toxoplasma.<\/li>\n
B\u1ec7nh t\u1ea3, b\u1ec7nh d\u1ecbch h\u1ea1ch.<\/li>\n<\/ul>\n
Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Cotrimoxazole 800\/160<\/h2>\n
C\u00e1ch d\u00f9ng<\/h3>\n
N\u00ean u\u1ed1ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n ho\u1eb7c \u0111\u1ed3 u\u1ed1ng \u0111\u1ec3 l\u00e0m gi\u1ea3m r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a.<\/p>\n
Cotrimoxazole 800\/160 li\u1ec1u d\u00f9ng<\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Tr\u01b0\u1eddng h\u1ee3p<\/td>\n Li\u1ec1u l\u01b0\u1ee3ng<\/td>\n<\/tr>\n
Vi\u00eam tai gi\u1eefa c\u1ea5p<\/td>\n Tr\u1ebb > 2 th\u00e1ng tu\u1ed5i: Li\u1ec1u th\u01b0\u1eddng d\u00f9ng l\u00e0 8mg trimethoprim (trong vi\u00ean cotrimoxazole)\/kg\/ng\u00e0y, chia 2 li\u1ec1u c\u00e1ch nhau 12 gi\u1edd, \u0111i\u1ec1u tr\u1ecb th\u01b0\u1eddng k\u00e9o d\u00e0i 10 ng\u00e0y.<\/td>\n<\/tr>\n
Nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u m\u1ea1n t\u00ednh ho\u1eb7c t\u00e1i ph\u00e1t ho\u1eb7c vi\u00eam ti\u1ec1n li\u1ec7t tuy\u1ebfn<\/td>\n Ng\u01b0\u1eddi l\u1edbn: 160mg trimethoprim (trong vi\u00ean cotrimoxazole) x 2 l\u1ea7n\/ng\u00e0y, c\u00e1ch nhau 12 gi\u1edd, d\u00f9ng trong 10 – 14 ng\u00e0y v\u1edbi nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u m\u1ea1n ho\u1eb7c t\u00e1i ph\u00e1t v\u00e0 \u0111i\u1ec1u tr\u1ecb trong 3 – 6 th\u00e1ng v\u1edbi vi\u00eam ti\u1ec1n li\u1ec7t tuy\u1ebfn.
\nD\u1ef1 ph\u00f2ng nhi\u1ec5m khu\u1ea9n m\u1ea1n ho\u1eb7c t\u00e1i ph\u00e1t \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u: Ng\u01b0\u1eddi l\u1edbn: 40 – 80mg trimethoprim (trong vi\u00ean cotrimoxazole)\/ng\u00e0y ho\u1eb7c m\u1ed9t tu\u1ea7n d\u00f9ng 3 l\u1ea7n trong 3 – 6 th\u00e1ng. Tr\u1ebb > 2 th\u00e1ng tu\u1ed5i th\u01b0\u1eddng u\u1ed1ng 8mg trimethoprim (trong vi\u00ean cotrimoxazole)\/kg\/ng\u00e0y, chia 2 li\u1ec1u nh\u1ecf c\u00e1ch nhau 12 gi\u1edd.<\/td>\n<\/tr>\n
Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p<\/td>\n Ng\u01b0\u1eddi l\u1edbn: 160mg trimethoprim (trong vi\u00ean cotrimoxazole)\/l\u1ea7n, ng\u00e0y d\u00f9ng 2 l\u1ea7n c\u00e1ch nhau 12 gi\u1edd, d\u00f9ng trong 14 ng\u00e0y.<\/td>\n<\/tr>\n
Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u00eau h\u00f3a g\u00e2y ra b\u1edfi l\u1ef5 tr\u1ef1c khu\u1ea9n<\/td>\n Ng\u01b0\u1eddi l\u1edbn: 160mg trimethoprim (trong vi\u00ean cotrimoxazole)\/\/l\u1ea7n, ng\u00e0y d\u00f9ng 2 l\u1ea7n c\u00e1ch nhau 12 gi\u1edd.
\nTr\u1ebb em: 8mg trimethoprim (trong vi\u00ean cotrimoxazole)\/kg\/ng\u00e0y, chia 2 li\u1ec1u nh\u1ecf c\u00e1ch nhau 12 gi\u1edd, d\u00f9ng trong 5 ng\u00e0y.<\/td>\n<\/tr>\n
B\u1ec7nh brucella<\/td>\n Tr\u1ebb em: li\u1ec1u trimethoprim (trong vi\u00ean cotrimoxazole) l\u00e0 10mg\/kg\/ng\u00e0y (t\u1ed1i \u0111a 480 mg\/ng\u00e0y), d\u00f9ng 2 l\u1ea7n\/ng\u00e0y trong 4 – 6 tu\u1ea7n.<\/td>\n<\/tr>\n
B\u1ec7nh t\u1ea3<\/td>\n Ng\u01b0\u1eddi l\u1edbn: 160mg trimethoprim (trong vi\u00ean cotrimoxazole), ng\u00e0y u\u1ed1ng 2 l\u1ea7n, trong 3 ng\u00e0y.
\nTr\u1ebb em: 4 – 5 mg\/kg trimethoprim (trong vi\u00ean cotrimoxazole), ng\u00e0y u\u1ed1ng 2 l\u1ea7n, trong 3 ng\u00e0y, ph\u1ed1i h\u1ee3p b\u00f9 d\u1ecbch v\u00e0 \u0111i\u1ec7n gi\u1ea3i.<\/td>\n<\/tr>\n
B\u1ec7nh d\u1ecbch h\u1ea1ch<\/td>\n \u0110i\u1ec1u tr\u1ecb d\u1ef1 ph\u00f2ng \u1edf ng\u01b0\u1eddi l\u1edbn: 320 – 640mg\u00a0 trimethoprim (trong vi\u00ean cotrimoxazole)\/ng\u00e0y, chia 2 l\u1ea7n c\u00e1ch nhau 12 gi\u1edd, trong 7 ng\u00e0y.
\nTr\u1ebb > 2 th\u00e1ng tu\u1ed5i: 8mg trimethoprim (trong vi\u00ean cotrimoxazole)\/kg\/ng\u00e0y, ng\u00e0y u\u1ed1ng 2 l\u1ea7n, trong 7 ng\u00e0y.<\/td>\n<\/tr>\n
Vi\u00eam ph\u1ed5i g\u00e2y ra b\u1edfi Pneumocystis jiroveci<\/td>\n Tr\u1ebb > 2 th\u00e1ng tu\u1ed5i v\u00e0 ng\u01b0\u1eddi l\u1edbn: 15 – 20mg trimethoprim (trong vi\u00ean cotrimoxazole)\/kg\/ng\u00e0y, chia \u0111\u1ec1u th\u00e0nh 3 – 4 li\u1ec1u, th\u1eddi gian \u0111i\u1ec1u tr\u1ecb th\u00f4ng th\u01b0\u1eddng k\u00e9o d\u00e0i 14 \u2013 21 ng\u00e0y.
\nD\u1ef1 ph\u00f2ng nhi\u1ec5m HIV cho ng\u01b0\u1eddi l\u1edbn v\u00e0 thi\u1ebfu ni\u00ean: li\u1ec1u 80 mg\/l\u1ea7n\/ng\u00e0y ho\u1eb7c 160mg\/l\u1ea7n\/ng\u00e0y trimethoprim u\u1ed1ng (trong vi\u00ean cotrimoxazole).
\nD\u1ef1 ph\u00f2ng cho tr\u1ebb em, bao g\u1ed3m c\u1ea3 tr\u1ebb nhi\u1ec5m HIV: U\u1ed1ng gi\u00e1n \u0111o\u1ea1n li\u1ec1u 150mg trimethoprim (trong vi\u00ean cotrimoxazole)\/m\u00e9t vu\u00f4ng, chia 2 l\u1ea7n, u\u1ed1ng li\u00ean ti\u1ebfp 3 ng\u00e0y m\u1ed7i tu\u1ea7n.<\/td>\n<\/tr>\n
B\u1ec7nh toxoplasma<\/td>\n D\u1ef1 ph\u00f2ng ti\u00ean ph\u00e1t cho ng\u01b0\u1eddi l\u1edbn v\u00e0 thi\u1ebfu ni\u00ean: li\u1ec1u 80 mg\/l\u1ea7n\/ng\u00e0y ho\u1eb7c 160mg\/l\u1ea7n\/ng\u00e0y trimethoprim u\u1ed1ng (trong vi\u00ean cotrimoxazole).
\nD\u1ef1 ph\u00f2ng ti\u00ean ph\u00e1t \u1edf tr\u1ebb em nhi\u1ec5m HIV: 150mg trimethoprim (trong vi\u00ean cotrimoxazole)\/m\u00e9t vu\u00f4ng, chia 2 l\u1ea7n.<\/td>\n<\/tr>\n
Suy th\u1eadn<\/td>\n \u0110\u1ed9 thanh th\u1ea3i creatinin:
\n>30 ml\/ph\u00fat: li\u1ec1u th\u00f4ng th\u01b0\u1eddng.
\n15 – 30 ml\/ph\u00fat: d\u00f9ng \u00bd li\u1ec1u th\u00f4ng th\u01b0\u1eddng.
\n< 15 ml\/ph\u00fat: Kh\u00f4ng d\u00f9ng.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Cotrimoxazole 800\/160 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n
\n
Qu\u00e1 m\u1eabn v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n
B\u1ec7nh nh\u00e2n c\u00f3 gan b\u1ecb t\u1ed5n th\u01b0\u01a1ng n\u1eb7ng.<\/li>\n
Suy th\u1eadn n\u1eb7ng: \u0111\u1ed9 thanh th\u1ea3i creatinin d\u01b0\u1edbi 15 ml\/ph\u00fat ho\u1eb7c kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c ch\u1ee9c n\u0103ng th\u1eadn.<\/li>\n
Thi\u1ebfu m\u00e1u h\u1ed3ng c\u1ea7u to.<\/li>\n
Ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa.<\/li>\n
Tr\u1ebb < 2 th\u00e1ng tu\u1ed5i.<\/li>\n<\/ul>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Cotrimoxazole 800\/160<\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
\n
Trong vi\u00eam h\u1ecdng g\u00e2y ra b\u1edfi S. Pyogenes: kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c n\u00e0y.<\/li>\n
C\u00e1c tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh: suy th\u1eadn, d\u1ecb \u1ee9ng n\u1eb7ng, b\u1ec7nh c\u00f3 nguy c\u01a1 thi\u1ebfu h\u1ee5t folat, hen ph\u1ebf qu\u1ea3n, thi\u1ebfu h\u1ee5t men G6PD c\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c.<\/li>\n
U\u1ed1ng cotrimoxazole c\u1ea7n l\u01b0u \u00fd u\u1ed1ng n\u01b0\u1edbc \u0111\u1ea7y \u0111\u1ee7 \u0111\u1ec3 tr\u00e1nh k\u1ebft tinh n\u01b0\u1edbc ti\u1ec3u v\u00e0 h\u00ecnh th\u00e0nh s\u1ecfi ni\u1ec7u.<\/li>\n
Th\u01b0\u1eddng xuy\u00ean ki\u1ec3m tra c\u00f4ng th\u1ee9c m\u00e1u, n\u01b0\u1edbc ti\u1ec3u, ch\u1ee9c n\u0103ng th\u1eadn khi d\u00f9ng cotrimoxazole l\u00e2u d\u00e0i.<\/li>\n
Ng\u01b0\u1eddi cao tu\u1ed5i l\u00e0 \u0111\u1ed1i t\u01b0\u1ee3ng hay g\u1eb7p t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a thu\u1ed1c.<\/li>\n<\/ul>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n\n\n\n\n\n\n\n\n
T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/td>\n Bi\u1ec3u hi\u1ec7n<\/td>\n<\/tr>\n
Th\u01b0\u1eddng g\u1eb7p<\/td>\n N\u00f4n,bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, bi\u1ebfng \u0103n<\/td>\n<\/tr>\n
Qu\u00e1 m\u1eabn<\/td>\n Th\u01b0\u1eddng g\u1eb7p: S\u1ed1t, vi\u00eam da tr\u00f3c v\u1ea3y, ban, ng\u1ee9a, nh\u1ea1y c\u1ea3m \u00e1nh s\u00e1ng v\u00e0 h\u1ed3ng ban.
\nNghi\u00eam tr\u1ecdng: c\u00e1c ph\u1ea3n \u1ee9ng tr\u00ean da, h\u1ed9i ch\u1ee9ng Stevens-Johnson, c\u00f3 th\u1ec3 t\u1eed vong.<\/td>\n<\/tr>\n
\u0110\u1ed9c tr\u00ean th\u1eadn<\/td>\n Vi\u00eam th\u1eadn k\u1ebd, ho\u1ea1i t\u1eed \u1ed1ng th\u1eadn, \u0111au th\u1eaft l\u01b0ng, ti\u1ec3u ra m\u00e1u, ti\u1ec3u \u00edt v\u00e0 kh\u00f3 ti\u1ec3u.<\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n m\u00e1u<\/td>\n M\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, gi\u1ea3m b\u1ea1ch c\u1ea7u, thi\u1ebfu m\u00e1u b\u1ea5t s\u1ea3n, gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m prothrombin, t\u0103ng b\u1ea1ch c\u1ea7u \u01b0a eosin.<\/td>\n<\/tr>\n
R\u1ed1i lo\u1ea1n gan<\/td>\n R\u1ed1i lo\u1ea1n h\u1ec7 enzym, v\u00e0ng da \u1ee9 m\u1eadt.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u01b0\u01a1ng t\u00e1c<\/h3>\n
\n
Warfarin: th\u1eddi gian \u0111\u00f4ng m\u00e1u c\u1ee7a b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 k\u00e9o d\u00e0i khi d\u00f9ng c\u00f9ng v\u1edbi Cotrimoxazole.<\/li>\n
Phenytoin b\u1ecb \u1ee9c ch\u1ebf s\u1ef1 chuy\u1ec3n h\u00f3a b\u1edfi Cotrimoxazole.<\/li>\n
Methotrexat: n\u1ed3ng \u0111\u1ed9 methotrexat t\u1ef1 do c\u00f3 th\u1ec3 l\u00e0m t\u0103ng khi d\u00f9ng c\u00f9ng Cotrimoxazole.<\/li>\n
Cyclosporin: \u0111\u1ed9c v\u1edbi th\u1eadn c\u00f3 th\u1ec3 x\u1ea3y ra nh\u01b0ng c\u00f3 th\u1ec3 h\u1ed3i ph\u1ee5c \u1edf b\u1ec7nh nh\u00e2n c\u1ea5y gh\u00e9p th\u1eadn khi d\u00f9ng cotrimoxazole c\u00f9ng v\u1edbi cyclosporin.<\/li>\n
Digoxin: khi d\u00f9ng c\u00f9ng cotrimoxazole l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 digoxin trong huy\u1ebft thanh, \u0111\u1eb7c bi\u1ec7t l\u00e0 ng\u01b0\u1eddi cao tu\u1ed5i.<\/li>\n
Indomethacin: c\u00f3 th\u1ec3 g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9 sulfamethoxazole khi d\u00f9ng c\u00f9ng Cotrimoxazole.<\/li>\n
Pyrimethamin: thi\u1ebfu m\u00e1u h\u1ed3ng c\u1ea7u to \u0111\u00e3 x\u1ea3y ra khi d\u00f9ng cotrimoxazole v\u00e0 pyrimethamin qu\u00e1 25 mg\/tu\u1ea7n.<\/li>\n
Thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m 3 v\u00f2ng khi d\u00f9ng Cotrimoxazole c\u00f3 th\u1ec3 b\u1ecb gi\u1ea3m hi\u1ec7u qu\u1ea3.<\/li>\n
Amantadin: \u0111\u00e3 x\u1ea3y ra m\u00ea s\u1ea3ng, nhi\u1ec5m \u0111\u1ed9c khi d\u00f9ng k\u1ebft h\u1ee3p v\u1edbi cotrimoxazole.<\/li>\n<\/ul>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n
\n
Ph\u1ee5 n\u1eef mang thai<\/li>\n<\/ul>\n
Cotrimoxazole c\u00f3 th\u1ec3 qua nhau thai, kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef mang thai v\u00ec nguy c\u01a1 g\u00e2y v\u00e0ng da \u1edf tr\u1ebb, tr\u1eeb tr\u01b0\u1eddng h\u1ee3p \u0111\u00e3 c\u00e2n nh\u1eafc c\u1ea9n th\u1eadn gi\u1eefa l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i.<\/p>\n
\n
Ph\u1ee5 n\u1eef cho con b\u00fa<\/li>\n<\/ul>\n
Cotrimoxazole qua \u0111\u01b0\u1ee3c s\u1eefa m\u1eb9, c\u00f3 nguy c\u01a1 g\u00e2y v\u00e0ng da \u1edf tr\u1ebb < 2 th\u00e1ng. N\u1ebfu d\u00f9ng thu\u1ed1c c\u1ea7n c\u00e2n nh\u1eafc d\u1eebng cho con b\u00fa ho\u1eb7c ng\u01b0\u1ee3c l\u1ea1i.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
Bi\u1ec3u hi\u1ec7n: sa s\u00fat tr\u00ed tu\u1ec7, l\u00fa l\u1eabn, \u0111au \u0111\u1ea7u, suy t\u1ee7y, n\u00f4n, bu\u1ed3n n\u00f4n, s\u01b0ng m\u1eb7t,…<\/p>\n
X\u1eed tr\u00ed: \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 k\u1ebft h\u1ee3p \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, g\u00e2y n\u00f4n ho\u1eb7c r\u1eeda d\u1ea1 d\u00e0y, c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p th\u1ea9m ph\u00e2n m\u00e1u. Th\u1ea9m ph\u00e2n m\u00e0ng b\u1ee5ng kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng.<\/p>\n
T\u00e1c \u0111\u1ed9ng tr\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n
T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n: m\u1ea5t ng\u1ee7, bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, \u00f9 tai,… c\u00f3 th\u1ec3 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n
Thu\u1ed1c Cotrimoxazole 800\/160 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n
Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Cotrimoxazole 800\/160<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n
K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n
Thu\u1ed1c Cotrimoxazole 400\/80<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH LD Stellapharm \u2013 Chi nh\u00e1nh 1, ch\u1ee9a Sulfamethoxazole 400mg v\u00e0 Trimethoprim 80mg. Thu\u1ed1c d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m khu\u1ea9n nh\u01b0 nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, ti\u1ebft ni\u1ec7u, ti\u00eau h\u00f3a, vi\u00eam tai gi\u1eefa c\u1ea5p t\u00ednh, vi\u00eam tuy\u1ebfn ti\u1ec1n li\u1ec7t, b\u1ec7nh t\u1ea3, b\u1ec7nh d\u1ecbch h\u1ea1ch. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n. \u0110\u1ed1i v\u1edbi b\u1ec7nh t\u1ea3 \u1edf ng\u01b0\u1eddi l\u1edbn b\u1ea1n c\u00f3 th\u1ec3 d\u00f9ng 160 mg trimethoprim (trong vi\u00ean cotrimoxazole) x 2 l\u1ea7n\/ng\u00e0y, trong 3 ng\u00e0y. Thu\u1ed1c c\u00f3 gi\u00e1 kho\u1ea3ng 115.000 \u0111\u1ed3ng\/ 1 h\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.<\/p>\n
Thu\u1ed1c Pms-Cotrim 960mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Imexpharm – Vi\u1ec7t Nam, ch\u1ee9a Sulfamethoxazole 800mg v\u00e0 Trimethoprim 160mg. Thu\u1ed1c d\u00f9ng \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n h\u00f4 h\u1ea5p (vi\u00eam ph\u1ebf qu\u1ea3n, vi\u00eam ph\u1ed5i, vi\u00eam tai gi\u1eefa, vi\u00eam xoang), nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u v\u00e0 sinh d\u1ee5c, nhi\u1ec5m khu\u1ea9n ti\u00eau h\u00f3a do l\u1ef5 tr\u1ef1c khu\u1ea9n. Trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u: U\u1ed1ng 1-2 vi\u00ean\/l\u1ea7n x 2 l\u1ea7n\/ng\u00e0y. Thu\u1ed1c c\u00f3 gi\u00e1 kho\u1ea3ng 63.000 \u0111\u1ed3ng\/ 1 h\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.<\/p>\n
T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Cotrimoxazole 800\/160?<\/h2>\n\n\n\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
Cotrimoxazole 800\/160 l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c kh\u00e1ng khu\u1ea9n \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb v\u00e0 ng\u0103n ng\u1eeba nhi\u1ec1u b\u1ec7nh nhi\u1ec5m tr\u00f9ng do vi khu\u1ea9n.<\/td>\n C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ch\u00ednh c\u1ee7a trimethoprim\/sulfamethoxazole bao g\u1ed3m ph\u00e1t ban, nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng, thi\u1ebfu h\u1ee5t folate.<\/td>\n<\/tr>\n
C\u00e1c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb c\u1ee7a thu\u1ed1c \u0111\u00e3 \u0111\u01b0\u1ee3c FDA ph\u00ea chu\u1ea9n bao g\u1ed3m \u0111\u1ee3t c\u1ea5p c\u1ee7a vi\u00eam ph\u1ebf qu\u1ea3n m\u00e3n t\u00ednh, vi\u00eam tai gi\u1eefa \u1edf tr\u1ebb em, nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u, vi\u00eam ph\u1ed5i do pneumocystis carinii v\u00e0 b\u1ec7nh toxoplasmosis.<\/td>\n Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y v\u00e0ng da \u1edf tr\u1ebb < 2 th\u00e1ng tu\u1ed5i.<\/td>\n<\/tr>\n
Khi s\u1eed d\u1ee5ng \u0111\u01a1n \u0111\u1ed9c sulfamethoxazole v\u00e0 trimethoprim ch\u1ec9 c\u00f3 t\u00e1c d\u1ee5ng k\u00ecm khu\u1ea9n. Tuy nhi\u00ean, khi s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p s\u1ebd c\u00f3 t\u00e1c d\u1ee5ng di\u1ec7t khu\u1ea9n. Ph\u1ed5 kh\u00e1ng khu\u1ea9n r\u1ed9ng tr\u00ean c\u1ea3 vi khu\u1ea9n Gram \u00e2m v\u00e0 Gram d\u01b0\u01a1ng.<\/td>\n <\/td>\n<\/tr>\n
Gi\u00e1 th\u00e0nh c\u1ee7a Cotrimoxazole 800\/160 kh\u00e1 r\u1ebb so v\u1edbi c\u00f4ng d\u1ee5ng tuy\u1ec7t v\u1eddi m\u00e0 n\u00f3 mang l\u1ea1i.<\/td>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n
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T\u00e1c gi\u1ea3 Tyler R. Kemnic v\u00e0 c\u1ed9ng s\u1ef1 (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 28 th\u00e1ng 11 n\u0103m 2022). Trimethoprim Sulfamethoxazole<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 17 th\u00e1ng 10 n\u0103m 2023, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/30020604\/<\/a><\/li>\n
T\u00e1c gi\u1ea3 F R Cockerill v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 11 n\u0103m 1991). Trimethoprim-sulfamethoxazole<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 17 th\u00e1ng 10 n\u0103m 2023, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/1749295\/<\/a><\/li>\n
T\u00e1c gi\u1ea3 J B Howard v\u00e0 c\u1ed9ng s\u1ef1. (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 11 n\u0103m 1978). Trimethoprim-sulfamethoxazole vs sulfamethoxazole for acute urinary tract infections in children<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 17 th\u00e1ng 10 n\u0103m 2023, https:\/\/pubmed.ncbi.nlm.nih.gov\/362893\/<\/a><\/li>\n
H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i b\u1ea3n PDF T\u1ea0I \u0110\u00c2Y<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
Thu\u1ed1c Cotrimoxazole 800\/160 ch\u1ee9a h\u1ed7n h\u1ee3p Sulfamethoxazole 800mg v\u00e0 Trimethoprim 160mg d\u00f9ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m khu\u1ea9n: vi\u00eam tai gi\u1eefa c\u1ea5p, nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u m\u1ea1n t\u00ednh ho\u1eb7c t\u00e1i ph\u00e1t ho\u1eb7c vi\u00eam ti\u1ec1n li\u1ec7t tuy\u1ebfn, nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p,<\/span> b\u1ec7nh t\u1ea3, b\u1ec7nh d\u1ecbch h\u1ea1ch…<\/p>\n","protected":false},"author":490,"featured_media":49527,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-49526","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/49526","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=49526"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/49527"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=49526"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=49526"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=49526"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Tr\u00ecnh b\u00e0y<\/h3>\nS\u0110K: VD-23966-15.\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.\nXu\u1ea5t x\u1ee9:Vi\u1ec7t Nam.<\/p>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Cotrimoxazole 800\/160<\/h2>\n

Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Cotrimoxazole 800\/160<\/h2>\n

C\u00e1ch d\u00f9ng<\/h3>\nN\u00ean u\u1ed1ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n ho\u1eb7c \u0111\u1ed3 u\u1ed1ng \u0111\u1ec3 l\u00e0m gi\u1ea3m r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a.<\/p>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Cotrimoxazole 800\/160<\/h2>\n

Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: VD-23966-15.
\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.
\nXu\u1ea5t x\u1ee9:Vi\u1ec7t Nam.<\/p>\n

C\u00e1ch d\u00f9ng<\/h3>\n
N\u00ean u\u1ed1ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n ho\u1eb7c \u0111\u1ed3 u\u1ed1ng \u0111\u1ec3 l\u00e0m gi\u1ea3m r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a.<\/p>\n