﻿{"id":47246,"date":"2023-10-06T02:26:20","date_gmt":"2023-10-05T19:26:20","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=47246"},"modified":"2025-07-24T14:02:01","modified_gmt":"2025-07-24T07:02:01","slug":"agifovir-f","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/agifovir-f\/","title":{"rendered":"AgiFovir- F"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c AgiFovir- F \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Agimexpharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 QL\u0110B-744-19.<\/b><\/p>\n<h2>AgiFovir<span style=\"font-weight: 400\">&#8211; F<\/span> l\u00e0 thu\u1ed1c g\u00ec<span style=\"font-weight: 400\">?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\"><strong>Thu\u1ed1c AgiFovir- F<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Efavirenz: 600mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Lamivudine: 300mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tenofovir disoproxil fumarat: 300mg t\u01b0\u01a1ng \u0111\u01b0\u01a1ng Tenofovir disoproxil 245mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u00e1c t\u00e1 d\u01b0\u1ee3c kh\u00e1c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: vi\u00ean n\u00e9n bao phim<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: QL\u0110B-744-19<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c AgiFovir- F<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng\u00a0<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tenofovir: l\u00e0 thu\u1ed1c kh\u00e1ng retrovirus (ARV), \u1ee9c ch\u1ebf s\u1ef1 phi\u00ean m\u00e3 ng\u01b0\u1ee3c l\u00e0m cho DNA c\u1ee7a virus kh\u00f4ng \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh \u0111\u1ec3 t\u1ea5n c\u00f4ng v\u00e0o nh\u00e2n t\u1ebf b\u00e0o v\u1eadt ch\u1ee7. Tenofovir disoproxil fumarat th\u1ee7y ph\u00e2n diester chuy\u1ec3n th\u00e0nh tenofovir sau \u0111\u00f3 phosphoryl h\u00f3a th\u00e0nh tenofovir diphosphat. Tenofovir diphosphat \u1ee9c ch\u1ebf ho\u1ea1t t\u00ednh c\u1ee7a men sao ch\u00e9p ng\u01b0\u1ee3c HIV-1 b\u1eb1ng c\u00e1ch c\u1ea1nh tranh v\u1edbi ch\u1ea5t n\u1ec1n t\u1ef1 nhi\u00ean deoxyadenosin-5\u2032 triphosphat v\u00e0 sau khi g\u1eafn k\u1ebft v\u00e0o DNA, k\u1ebft th\u00fac chu\u1ed7i DNA. Tenofovir diphosphat l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf y\u1ebfu men \u03b1 v\u00e0 \u03b2-DNA polymerase c\u1ee7a \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa v\u00e0 men \u03b3 -DNA polymerase \u1edf \u0111\u1ed9ng v\u1eadt c\u00f3 x\u01b0\u01a1ng s\u1ed1ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Lamivudine: Lamivudin thu\u1ed9c nh\u00f3m nucleotid \u01b0\u0301c ch\u00ea\u0301 enzym phi\u00ean m\u00e3 ng\u01b0\u01a1\u0323c. N\u00f3 \u0111\u01b0\u1ee3c c\u00e1c enzym trong t\u1ebf b\u00e0o chuy\u1ec3n th\u00e0nh d\u1eabn xu\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh l\u00e0 lamivudin 5\u2019-triphosphat (3TC-TP). 3TC-TP c\u1ea1nh tranh v\u1edbi deoxycytidin triphosphat t\u1ef1 nhi\u00ean v\u00e0 l\u00e0m s\u1ef1 t\u1ed5ng h\u1ee3p DNA c\u1ee7a virus b\u1ecb k\u1ebft th\u00fac s\u1edbm. Lamivudin c\u00f3 ho\u1ea1t t\u00ednh l\u00ean virus HIV typ1, 2 v\u00e0 \u1ee9c ch\u1ebf virus vi\u00eam gan B \u1edf ng\u01b0\u1eddi b\u1ec7nh m\u1ea1n t\u00ednh.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Efavirenz: Efavirenz thu\u1ed9c nh\u00f3m kh\u00f4ng nucleosid, c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf kh\u00f4ng c\u1ea1nh tranh nh\u01b0ng \u0111\u1eb7c hi\u1ec7u l\u00ean enzym phi\u00ean m\u00e3 ng\u01b0\u01a1\u0323c c\u1ee7a HIV-1, do \u0111\u00f3 \u1ee9c ch\u1ebf s\u1ef1 nh\u00e2n l\u00ean c\u1ee7a HIV-1. Thu\u1ed1c kh\u00f4ng g\u1eafn \u0111\u01b0\u1ee3c v\u00e0o enzym phi\u00ean m\u00e3 ng\u01b0\u01a1\u0323c c\u1ee7a HIV- 2, n\u00ean kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng l\u00ean HIV- 2. Tr\u00ean HIV-1, efavirenz c\u00f3 t\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng v\u1edbi c\u00e1c nucleosid \u01b0\u0301c ch\u00ea\u0301 enzym phi\u00ean m\u00e3 ng\u01b0\u01a1\u0323c v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf protease c\u1ee7a HIV.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<table style=\"width: 100%;height: 443px\">\n<thead>\n<tr style=\"height: 71px\">\n<th style=\"height: 71px\"><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m<\/span><\/th>\n<th style=\"height: 71px\"><span style=\"font-weight: 400\">Tenofovir<\/span><\/th>\n<th style=\"height: 71px\"><span style=\"font-weight: 400\">Lamivudine<\/span><\/th>\n<th style=\"height: 71px\"><span style=\"font-weight: 400\">Efavirenz<\/span><\/th>\n<\/tr>\n<tr style=\"height: 115px\">\n<th style=\"height: 115px\"><span style=\"font-weight: 400\">H\u1ea5p thu<\/span><\/th>\n<th style=\"text-align: left;height: 115px\"><span style=\"font-weight: 400\">H\u1ea5p thu nhanh, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t sau 1- 2 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng thu\u1ed1c \u01a1\u0309 ng\u01b0\u01a1\u0300i \u0111o\u0301i kho\u1ea3ng 25% v\u00e0 t\u0103ng cao khi u\u1ed1ng v\u1edbi b\u1eefa \u0103n gi\u00e0u ch\u1ea5t b\u00e9o.<\/span><\/th>\n<th style=\"text-align: left;height: 115px\"><span style=\"font-weight: 400\">H\u1ea5p thu nhanh, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nhtrong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t sau kho\u1ea3ng 1 gi\u1edd l\u00fac \u0111\u00f3i v\u00e0 3,2 gi\u1edd l\u00fac no. Th\u1ee9c \u0103n l\u00e0m ch\u1eadm nh\u01b0ng kh\u00f4ng l\u00e0m gi\u1ea3m h\u1ea5p thu thu\u1ed1c. Sinh kh\u1ea3 d\u1ee5ng \u1edf ng\u01b0\u1eddi l\u1edbn nhi\u1ec5m HIV kho\u1ea3ng 80-87%<\/span><\/th>\n<th style=\"text-align: left;height: 115px\"><span style=\"font-weight: 400\">N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u1ee7a efavirenz trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c 3-5 gi\u1edd sau m\u1ed7i l\u1ea7n u\u1ed1ng v\u00e0 n\u1ed3ng \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 6-7 ng\u00e0y u\u1ed1ng thu\u1ed1c li\u00ean t\u1ee5c. Sinh kh\u1ea3 d\u1ee5ng t\u0103ng khi u\u1ed1ng thu\u1ed1c sau b\u1eefa \u0103n gi\u00e0u ch\u1ea5t b\u00e9o.\u00a0<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"height: 71px\">\n<td style=\"height: 71px\"><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1<\/span><\/td>\n<td style=\"text-align: left;height: 71px\"><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i trong c\u00e1c m\u00f4, \u0111\u1eb7c bi\u1ec7t \u1edf th\u1eadn v\u00e0 gan<\/span><\/td>\n<td style=\"text-align: left;height: 71px\"><span style=\"font-weight: 400\">Kho\u1ea3ng 10% lamivudin qua h\u00e0ng r\u00e0o m\u00e1u n\u00e3o. T\u1ef7 l\u1ec7 n\u1ed3ng \u0111\u1ed9 trong d\u1ecbch n\u00e3o t\u1ee7y\/n\u1ed3ng \u0111\u1ed9 huy\u1ebft thanh l\u00e0 0,12.<\/span><\/td>\n<td style=\"text-align: left;height: 71px\"><span style=\"font-weight: 400\"> Thu\u1ed1c \u0111i qua h\u00e0ng r\u00e0o m\u00e1u-n\u00e3o v\u00e0 c\u00f3 trong d\u1ecbch n\u00e3o t\u1ee7y.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 71px\">\n<td style=\"height: 71px\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a<\/span><\/td>\n<td style=\"text-align: left;height: 71px\"><span style=\"font-weight: 400\">N\u01b0\u0309a \u0111\u01a1\u0300i th\u1ea3i tr\u1eeb c\u1ee7a tenofovir l\u00e0 12- 18 gi\u1edd.<\/span><\/td>\n<td style=\"text-align: left;height: 71px\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a trong t\u1ebf b\u00e0o th\u00e0nh d\u1ea1ng triphosphat c\u00f3 ho\u1ea1t t\u00ednh, Lamivudine b\u1ecb chuy\u1ec3n h\u00f3a \u00edt \u1edf gan.<\/span><\/td>\n<td style=\"text-align: left;height: 71px\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu qua h\u1ec7 th\u1ed1ng cytochrom P450 th\u00e0nh d\u1ea1ng kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng.<\/span><\/td>\n<\/tr>\n<tr style=\"height: 115px\">\n<td style=\"height: 115px\"><span style=\"font-weight: 400\">Th\u1ea3i tr\u1eeb<\/span><\/td>\n<td style=\"text-align: left;height: 115px\"><span style=\"font-weight: 400\">\u0110a\u0300o tha\u0309i chu\u0309 y\u00ea\u0301u qua n\u01b0\u01a1\u0301c ti\u00ea\u0309u\u00a0<\/span><\/td>\n<td style=\"text-align: left;height: 115px\"><span style=\"font-weight: 400\">\u0110\u00e0o th\u1ea3i ph\u1ea7n l\u1edbn qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/span><\/td>\n<td style=\"text-align: left;height: 115px\"><span style=\"font-weight: 400\">14-34% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i theo n\u01b0\u1edbc ti\u1ec3u ch\u1ee7 y\u1ebfu d\u01b0\u1edbi d\u1ea1ng chuy\u1ec3n ho\u00e1, &lt; 1% \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i. 16-61% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i theo ph\u00e2n ch\u1ee7 y\u1ebfu d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c AgiFovir- F \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c AgiFovir- F k\u1ebft h\u1ee3p li\u1ec1u c\u1ed1 \u0111\u1ecbnh tenofovir disoproxil fumarat, lamivudin v\u00e0 efavirenz \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p thu\u1ed1c kh\u00e1ng retrovirus cho ng\u01b0\u1eddi l\u1edbn tr\u00ean 18 tu\u1ed5i b\u1ecb nhi\u1ec5m HIV-1.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c AgiFovir- F<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Li\u1ec1u khuy\u1ebfn c\u00e1o c\u1ee7a AgiFovir- F l\u00e0 u\u1ed1ng 1 vi\u00ean\/ l\u1ea7n\/ ng\u00e0y.<\/span><\/p>\n<p><span style=\"font-weight: 400\">AgiFovir- F d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u00ean u\u1ed1ng thu\u1ed1c xa b\u1eefa \u0103n, t\u1ed1t nh\u1ea5t v\u00e0o bu\u1ed5i t\u1ed1i tr\u01b0\u1edbc khi \u0111i ng\u1ee7 \u0111\u1ec3 gi\u1ea3m c\u00e1c ph\u1ea3n \u1ee9ng ph\u1ee5 c\u1ee7a efavirenz tr\u00ean h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c AgiFovir- F trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">M\u1eabn c\u1ea3m v\u1edbi tenofovir, lamivudin, efavirenz ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a AgiFovir- F.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">B\u1ec7nh th\u1eadn n\u1eb7ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Suy gan n\u1eb7ng.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c AgiFovir- F<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4ng d\u00f9ng AgiFovir- F c\u00f9ng v\u1edbi b\u1ea5t k\u1ef3 thu\u1ed1c n\u00e0o kh\u00e1c c\u00f3 ch\u1ee9a tenofovir disoproxil fumarat ho\u1eb7c lamivudin ho\u1eb7c efavirenz.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4ng d\u00f9ng \u0111\u1ed3ng th\u1eddi AgiFovir- F v\u1edbi didanosin, thu\u1ed1c ch\u1ee9a cytidin (emtricitabin), thu\u1ed1c ch\u1ee9a adefovir dipivoxil.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn th\u01b0\u1eddng xuy\u00ean h\u01a1n \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1, ti\u1ec1n s\u1eed suy th\u1eadn v\u00e0 nh\u1eefng b\u1ec7nh nh\u00e2n suy th\u1eadn.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tr\u00e1nh s\u1eed d\u1ee5ng AgiFovir- F \u0111\u1ed3ng th\u1eddi ho\u1eb7c n\u1ebfu g\u1ea7n \u0111\u00e2y b\u1ec7nh nh\u00e2n v\u1eeba s\u1eed d\u1ee5ng m\u1ed9t s\u1ea3n ph\u1ea9m thu\u1ed1c g\u00e2y \u0111\u1ed9c cho th\u1eadn. N\u1ebfu b\u1eaft bu\u1ed9c ph\u1ea3i d\u00f9ng chung c\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn h\u00e0ng tu\u1ea7n<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tr\u00e1nh d\u00f9ng \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e3 t\u1eebng \u0111i\u1ec1u tr\u1ecb v\u1edbi thu\u1ed1c kh\u00e1ng retrovirus c\u00f3 ch\u1ee7ng \u0111\u1ed9t bi\u1ebfn K65R.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng khi d\u00f9ng AgiFovir- F \u0111i\u1ec1u tr\u1ecb cho nh\u1eefng b\u1ec7nh nh\u00e2n l\u1edbn tu\u1ed5i\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb vi\u00eam gan B, C m\u00e3n t\u00ednh v\u00e0 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb v\u1edbi tr\u1ecb li\u1ec7u kh\u00e1ng retrovirus k\u1ebft h\u1ee3p c\u00f3 nguy c\u01a1 t\u0103ng c\u00e1c ph\u1ea3n \u1ee9ng kh\u00f4ng mong mu\u1ed1n \u1edf gan n\u1eb7ng v\u00e0 c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan tr\u01b0\u1edbc \u0111\u00f3 k\u1ec3 c\u1ea3 vi\u00eam gan m\u00e3n t\u00ednh th\u1ec3 ho\u1ea1t \u0111\u1ed9ng c\u00f3 s\u1ef1 t\u0103ng t\u1ea7n s\u1ed1 xu\u1ea5t hi\u1ec7n c\u00e1c b\u1ea5t th\u01b0\u1eddng v\u1ec1 ch\u1ee9c n\u0103ng trong su\u1ed1t th\u1eddi gian tr\u1ecb li\u1ec7u kh\u00e1ng retrovirus k\u1ebft h\u1ee3p c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i. N\u1ebfu b\u1ec7nh gan tr\u1edf n\u00ean x\u1ea5u h\u01a1n ph\u1ea3i c\u00e2n nh\u1eafc \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb gi\u00e1n \u0111o\u1ea1n ho\u1eb7c ng\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u1ede nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c g\u00e2y \u0111\u1ed9c gan c\u1ea7n gi\u00e1m s\u00e1t c\u00e1c enzym gan.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u00ean ng\u01b0ng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng AgiFovir- F (do tenofovir c\u00f3 c\u1ea5u tr\u00fac li\u00ean quan \u0111\u1ebfn c\u00e1c \u0111\u1ed3ng \u0111\u1eb3ng nucleosid) n\u1ebfu c\u00f3 s\u1ef1 t\u0103ng lactat huy\u1ebft c\u00f3 tri\u1ec7u ch\u1ee9ng v\u00e0 nhi\u1ec5m acid lactic\/ nhi\u1ec5m acid chuy\u1ec3n h\u00f3a, ch\u1ee9ng gan to ti\u1ebfn tri\u1ec3n, ho\u1eb7c s\u1ef1 t\u0103ng nhanh n\u1ed3ng \u0111\u1ed9 aminotransferase.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u00ean th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00e1c \u0111\u1ed3ng \u0111\u1eb3ng nucleosid cho b\u1ea5t k\u1ef3 b\u1ec7nh nh\u00e2n n\u00e0o c\u00f3 ch\u1ee9ng gan to, vi\u00eam gan ho\u1eb7c c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 kh\u00e1c \u0111\u01b0\u1ee3c bi\u1ebft cho b\u1ec7nh gan v\u00e0 ch\u1ee9ng nhi\u1ec5m m\u1ee1 \u1edf gan.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea7n duy tr\u00ec vi\u1ec7c theo d\u00f5i l\u00e2m s\u00e0ng ch\u1eb7t ch\u1ebd b\u1edfi nh\u1eefng th\u1ea7y thu\u1ed1c c\u00f3 kinh nghi\u1ec7m trong \u0111i\u1ec1u tr\u1ecb nh\u1eefng b\u1ec7nh li\u00ean quan \u0111\u1ebfn HIV \u0111\u1ec3 tr\u00e1nh x\u1ea3y ra nhi\u1ec5m tr\u00f9ng c\u01a1 h\u1ed9i\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tr\u1ecb li\u1ec7u kh\u00e1ng retrovirus, k\u1ec3 c\u1ea3 thu\u1ed1c k\u1ebft h\u1ee3p li\u1ec1u c\u1ed1 \u0111\u1ecbnh nh\u01b0 AgiFovir- F kh\u00f4ng ng\u0103n ng\u1eeba \u0111\u01b0\u1ee3c nguy c\u01a1 l\u00e2y truy\u1ec1n HIV cho nh\u1eefng ng\u01b0\u1eddi kh\u00e1c th\u00f4ng qua quan h\u1ec7 t\u00ecnh d\u1ee5c hay s\u1ef1 l\u00e2y nhi\u1ec5m qua m\u00e1u. C\u1ea7n s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba th\u00edch h\u1ee3p \u0111\u1ec3 ng\u0103n ng\u1eeba l\u00e2y truy\u1ec1n HIV.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u00ean ki\u1ec3m tra l\u00e2m s\u00e0ng k\u1ec3 c\u1ea3 \u0111\u00e1nh gi\u00e1 c\u00e1c d\u1ea5u hi\u1ec7u th\u1ec3 ch\u1ea5t c\u1ee7a s\u1ef1 ph\u00e2n b\u1ed1 l\u1ea1i m\u1ee1, \u0111o lipid huy\u1ebft thanh v\u00e0 glucose huy\u1ebft l\u00fac nh\u1ecbn \u0103n, ki\u1ec3m so\u00e1t s\u1ef1 r\u1ed1i lo\u1ea1n lipid \u0111\u1ec3 tr\u00e1nh lo\u1ea1n d\u01b0\u1ee1ng m\u1ee1 v\u00e0 nh\u1eefng b\u1ea5t th\u01b0\u1eddng v\u1ec1 chuy\u1ec3n h\u00f3a<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Theo d\u00f5i c\u00e1c b\u1ea5t th\u01b0\u1eddng v\u1ec1 x\u01b0\u01a1ng, v\u00ec tenofovir c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m m\u1eadt \u0111\u1ed9 x\u01b0\u01a1ng, ph\u1ea3i theo d\u00f5i x\u01b0\u01a1ng \u1edf ng\u01b0\u1eddi c\u00f3 b\u1ec7nh s\u1ecfi b\u1ecb g\u00e3y x\u01b0\u01a1ng, ho\u1eb7c c\u00f3 nguy c\u01a1 lo\u00e3ng x\u01b0\u01a1ng. C\u1ea7n g\u1eb7p b\u00e1c s\u0129 n\u1ebfu b\u1ecb \u0111au v\u00e0 nh\u1ee9c kh\u1edbp, c\u1ee9ng kh\u1edbp ho\u1eb7c kh\u00f3 kh\u0103n trong vi\u1ec7c di chuy\u1ec3n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng AgiFovir- F cho nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e3 c\u00f3 ph\u1ea3n \u1ee9ng da \u0111e d\u1ecda t\u00ednh m\u1ea1ng (v\u00ed d\u1ee5 h\u1ed9i ch\u1ee9ng Stevens-Johnson) khi d\u00f9ng m\u1ed9t NNRTI.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n n\u00ean g\u1eb7p b\u00e1c s\u0129 n\u1ebfu c\u00f3 c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 tr\u1ea7m c\u1ea3m n\u1eb7ng, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n, c\u00f3 \u00fd ngh\u0129 t\u1ef1 s\u00e1t \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 kh\u1ea3 n\u0103ng nh\u1eefng tri\u1ec7u ch\u1ee9ng n\u00e0y c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c d\u00f9ng thu\u1ed1c ch\u1ee9a efavirenz hay kh\u00f4ng. N\u1ebfu c\u00f3, b\u00e1c s\u0129 c\u1ea7n x\u00e1c \u0111\u1ecbnh xem nh\u1eefng nguy c\u01a1 c\u1ee7a vi\u1ec7c ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb c\u00f3 h\u01a1n h\u1eb3n nh\u1eefng l\u1ee3i \u00edch mang l\u1ea1i hay kh\u00f4ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e3 c\u00f3 ti\u1ec1n s\u1eed \u0111\u1ed9ng kinh.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n cao tu\u1ed5i c\u00f3 kh\u1ea3 n\u0103ng ch\u1ee9c n\u0103ng gan ho\u1eb7c th\u1eadn gi\u1ea3m n\u00ean c\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng AgiFovir- F\u00a0<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/h3>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400\">Hay g\u1eb7p<\/span><\/td>\n<td><span style=\"font-weight: 400\">T\u0103ng triglycerid l\u00fac \u0111\u00f3i, cholesterol to\u00e0n ph\u1ea7n, lipoprotein cholesterol t\u1ec9 tr\u1ecdng cao v\u00e0 cholesterol t\u1ec9 tr\u1ecdng th\u1ea5p, gi\u1ea3m phosphat m\u00e1u, ho, tri\u1ec7u ch\u1ee9ng \u1edf m\u0169i, ch\u00f3ng m\u1eb7t, r\u1ed1i lo\u1ea1n ch\u00fa \u00fd, nh\u1ee9c \u0111\u1ea7u, m\u1ea5t ng\u1ee7, bu\u1ed3n ng\u1ee7, lo \u00e2u, tr\u1ea7m c\u1ea3m\u2026<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">\u00cdt g\u1eb7p<\/span><\/td>\n<td><span style=\"font-weight: 400\">Gi\u1ea3m b\u1ea1ch c\u1ea7u, thi\u1ebfu m\u00e1u, gi\u1ea3m ti\u1ec3u c\u1ea7u, k\u00edch \u0111\u1ed9ng, m\u1ea5t tr\u00ed nh\u1edb, m\u1ea5t \u0111i\u1ec1u h\u00f2a, l\u00fa l\u1eabn, co gi\u1eadt, hung h\u0103ng, h\u01b0ng ph\u1ea5n, \u1ea3o gi\u00e1c, h\u01b0ng c\u1ea3m, hoang t\u01b0\u1edfng, c\u00f3 \u00fd t\u01b0\u1edfng ho\u1eb7c mu\u1ed1n t\u1ef1 t\u1eed, vi\u00eam gan c\u1ea5p, h\u1ed9i ch\u1ee9ng Stevens-Johnson\u2026<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Hi\u1ebfm g\u1eb7p<\/span><\/td>\n<td><span style=\"font-weight: 400\">Nhi\u1ec5m acid lactic, suy th\u1eadn, b\u1ec7nh l\u00fd \u1ed1ng th\u1eadn, t\u0103ng creatinin huy\u1ebft<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">R\u1ea5t hi\u1ebfm g\u1eb7p<\/span><\/td>\n<td><span style=\"font-weight: 400\">B\u1ea5t s\u1ea3n h\u1ed3ng c\u1ea7u, kh\u00f3 th\u1edf, b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean, ho\u1ea1i t\u1eed \u1ed1ng th\u1eadn c\u1ea5p<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Ch\u01b0a r\u00f5 t\u1ea7n su\u1ea5t<\/span><\/td>\n<td><span style=\"font-weight: 400\">Lo\u1ea1n d\u01b0\u1ee1ng m\u1ee1, h\u1ea1 kali m\u00e1u, run, lo\u1ea1n th\u1ea7n, suy gan, gan nhi\u1ec5m m\u1ee1, vi\u00eam th\u1eadn, ti\u00eau c\u01a1 v\u00e2n, nhuy\u1ec5n x\u01b0\u01a1ng, y\u1ebfu c\u01a1, b\u1ec7nh c\u01a1, ho\u1ea1i t\u1eed x\u01b0\u01a1ng, \u00f9 tai, h\u1ed9i ch\u1ee9ng ph\u1ee5c h\u1ed3i mi\u1ec5n d\u1ecbch, \u0111\u1ecf b\u1eebng m\u1eb7t<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400\">C\u00e1c thu\u1ed1c ch\u1ecbu \u1ea3nh h\u01b0\u1edfng ho\u1eb7c th\u1ea3i tr\u1eeb qua th\u1eadn<\/span><\/td>\n<td><span style=\"font-weight: 400\">L\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 tenofovir ho\u1eb7c c\u00e1c thu\u1ed1c d\u00f9ng chung.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Thu\u1ed1c \u1ee9c ch\u1ebf protease HIV, thu\u1ed1c \u1ee9c ch\u1ebf men sao ch\u00e9p ng\u01b0\u1ee3c nucleosid\/ kh\u00f4ng nucleosid<\/span><\/td>\n<td><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c c\u1ed9ng h\u1ee3p hay \u0111\u1ed3ng v\u1eadn gi\u1eefa tenofovir v\u00e0 c\u00e1c thu\u1ed1c n\u00e0y<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Aminoglycosid, polypeptid, glucopeptid, polymyxin, amphotericin B.<\/span><\/td>\n<td><span style=\"font-weight: 400\">C\u00f3 th\u1ec3 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng g\u00e2y \u0111\u1ed9c cho th\u1eadn<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Zalcitabin<\/span><\/td>\n<td><span style=\"font-weight: 400\">Lamivudin c\u00f3 th\u1ec3 \u1ee9c ch\u1ebf s\u1ef1 phosphoryl h\u00f3a n\u1ed9i b\u00e0o c\u1ee7a zalcitabin<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Terfenadin, astemizol, cisaprid, midazolam, triazolam, pimozid, bepridil ho\u1eb7c c\u00e1c alkaloid n\u1ea5m c\u1ef1a g\u00e0<\/span><\/td>\n<td><span style=\"font-weight: 400\">\u1ee8c ch\u1ebf s\u1ef1 chuy\u1ec3n h\u00f3a c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c tr\u01b0\u1eddng h\u1ee3p nghi\u00eam tr\u1ecdng, \u0111e d\u1ecda t\u00ednh m\u1ea1ng.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Voriconazol<\/span><\/td>\n<td><span style=\"font-weight: 400\">Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng \u0111\u1ed3ng th\u1eddi AgiFovir- F v\u00e0 voriconazol.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">atorvastatin, pravastatin, simvastatin<\/span><\/td>\n<td><span style=\"font-weight: 400\">L\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a statin. N\u00ean theo d\u00f5i \u0111\u1ecbnh k\u1ef3 n\u1ed3ng \u0111\u1ed9 cholesterol v\u00e0 c\u00f3 th\u1ec3 c\u1ea7n ph\u1ea3i \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u c\u1ee7a statin.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Methadon<\/span><\/td>\n<td><span style=\"font-weight: 400\">L\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a methadon d\u1eabn \u0111\u1ebfn c\u00e1c d\u1ea5u hi\u1ec7u cai nghi\u1ec7n thu\u1ed1c phi\u1ec7n. C\u1ea7n theo d\u00f5i c\u00e1c d\u1ea5u hi\u1ec7u cai nghi\u1ec7n v\u00e0 t\u0103ng li\u1ec1u methadon \u0111\u1ec3 l\u00e0m gi\u1ea3m h\u1ed9i ch\u1ee9ng cai thu\u1ed1c.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">Th\u1ea3o d\u01b0\u1ee3c St.John\u00a0 hay c\u00e2y n\u1ecdc s\u1edfi\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400\">N\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a efavirenz c\u00f3 th\u1ec3 b\u1ecb gi\u1ea3m d\u1eabn \u0111\u1ebfn gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a efavirenz.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef c\u00f3 thai: Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng AgiFovir- F trong th\u1eddi k\u1ef3 mang thai tr\u1eeb khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ee5 n\u1eef cho con b\u00fa: Lamivudin \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft va\u0300o s\u01b0\u0303a m\u1eb9, ch\u01b0a ro\u0303 tenofovir v\u00e0 efavirenz co\u0301 \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft va\u0300o s\u01b0\u0303a m\u1eb9 hay kh\u00f4ng. Hi\u1ec7n ch\u01b0a c\u00f3 \u0111\u1ee7 th\u00f4ng tin v\u1ec1 nh\u1eefng t\u00e1c \u0111\u1ed9ng c\u1ee7a tenofovir, lamivudin, efavirenz \u1edf tr\u1ebb s\u01a1 sinh, v\u00ec v\u1eady kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c n\u00e0y cho ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa. Ngo\u00e0i ra, nh\u1eefng ph\u1ee5 n\u1eef b\u1ecb nhi\u1ec5m HIV \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o kh\u00f4ng cho con b\u00fa trong b\u1ea5t k\u1ef3 ho\u00e0n c\u1ea3nh n\u00e0o \u0111\u1ec3 tr\u00e1nh l\u00e2y truy\u1ec1n HIV cho con.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<table>\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400\">Tri\u1ec7u ch\u1ee9ng<\/span><\/td>\n<td><span style=\"font-weight: 400\">C\u00f3 r\u1ea5t \u00edt th\u00f4ng tin v\u1ec1 qu\u00e1 li\u1ec1u AgiFovir- F.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u do efavirenz ch\u1ee7 y\u1ebfu l\u00e0 bi\u1ec3u hi\u1ec7n r\u1ed1i lo\u1ea1n th\u1ea7n kinh: Kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c v\u1eadn \u0111\u1ed9ng, ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u, kh\u00f3 t\u1eadp trung, b\u1ed3n ch\u1ed3n, l\u00fa l\u1eabn, qu\u00ean, kh\u00f3 ng\u1ee7, co gi\u1eadt c\u00e1c c\u01a1<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400\">X\u1eed tr\u00ed<\/span><\/td>\n<td><span style=\"font-weight: 400\">B\u1ec7nh nh\u00e2n ph\u1ea3i \u0111\u01b0\u1ee3c theo d\u00f5i c\u00e1c d\u1ea5u hi\u1ec7u ng\u1ed9 \u0111\u1ed9c v\u00e0 d\u00f9ng c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb tri\u00ea\u0323u ch\u01b0\u0301ng va\u0300 \u0111i\u00ea\u0300u tri\u0323 h\u1ed7 tr\u1ee3 khi c\u1ea7n thi\u1ebft. Tr\u01a1\u0323 giu\u0301p v\u00ea\u0300 t\u00e2m ly\u0301 cho b\u00ea\u0323nh nh\u00e2n t\u01b0\u0323 sa\u0301t b\u0103\u0300ng thu\u00f4\u0301c.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tenofovir: C\u00f3 th\u1ec3 lo\u1ea1i b\u1ecf b\u1eb1ng th\u1ea9m ph\u00e2n m\u00e1u<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Lamivudin: Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u lamivudin. Th\u1ea9m t\u00e1ch m\u00e1u ho\u1eb7c th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c sau 4 gi\u1edd ch\u1ec9 l\u1ea5y \u0111i \u0111\u01b0\u1ee3c m\u1ed9t l\u01b0\u1ee3ng kh\u00f4ng \u0111\u00e1ng k\u1ec3.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Efavirenz: Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u efavirenz. N\u1ebfu v\u1eeba u\u1ed1ng xong c\u1ea7n g\u00e2y n\u00f4n, r\u1eeda d\u1ea1 d\u00e0y, c\u00f3 th\u1ec3 cho b\u1ec7nh nh\u00e2n u\u1ed1ng than ho\u1ea1t t\u00ednh \u0111\u1ec3 h\u1ed7 tr\u1ee3 lo\u1ea1i b\u1ecf efavirenz ch\u01b0a \u0111\u01b0\u1ee3c h\u1ea5p thu. \u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, theo d\u00f5i ch\u1eb7t ch\u1ebd c\u00e1c tri\u1ec7u ch\u1ee9ng tim m\u1ea1ch, h\u00f4 h\u1ea5p.<\/span><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Thu\u1ed1c AgiFovir<span style=\"font-weight: 400\">&#8211; F<\/span> gi\u00e1<span style=\"font-weight: 400\"> bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c AgiFovir- F hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c AgiFovir- F t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c AgiFovir- F nh\u01b0:\u00a0\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400\"><a href=\"https:\/\/vnras.com\/drug\/36863\/\">Acriptega<\/a> c\u00f3 ch\u1ee9a <\/span><span style=\"font-weight: 400\">Dolutegravir, Lamivudin, Tenofovir disoproxil c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m HIV 1,2 v\u00e0 vi\u00eam gan B<\/span><span style=\"font-weight: 400\">. Acriptega \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi\u00a0 C\u00f4ng Ty D\u01b0\u1ee3c Ph\u1ea9m Mylan Laboratories Limited, h\u1ed9p c\u00f3 1 l\u1ecd 30 vi\u00ean v\u00e0 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng v\u1edbi gi\u00e1 1,250,000\u0111.<\/span><\/li>\n<li><span style=\"font-weight: 400\"><a href=\"https:\/\/vnras.com\/drug\/efavirenz-stada-600-mg\/\">Efavirenz stada 600 mg<\/a> ch\u1ee9a Efavirenz<\/span><span style=\"font-weight: 400\"> c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m HIV<\/span><span style=\"font-weight: 400\">. Efavirenz stada 600 mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng Ty Tr\u00e1ch nhi\u1ec7m h\u1eefu h\u1ea1n LD Stada, h\u1ed9p c\u00f3 3 v\u1ec9 x 10 vi\u00ean v\u00e0 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng v\u1edbi gi\u00e1 545,000\u0111.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c AgiFovir- F?<\/span><\/h2>\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 73.175%\"><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 26.2093%\"><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 73.175%\">\n<ul>\n<li><span style=\"font-weight: 400\">AgiFovir- F \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean n\u00e9n n\u00ean ti\u1ec7n l\u1ee3i, d\u1ec5 s\u1eed d\u1ee5ng, b\u1ea3o qu\u1ea3n v\u00e0 mang theo.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">K\u1ebft h\u1ee3p li\u1ec1u c\u1ed1 \u0111\u1ecbnh Tenofovir Disoproxil Fumarate, Lamivudine v\u00e0 Efavirenz c\u00f3 hi\u1ec7u qu\u1ea3 v\u00e0 dung n\u1ea1p t\u1ed1t trong \u0111i\u1ec1u tr\u1ecb HIV-1<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Efavirenz l\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf men sao ch\u00e9p ng\u01b0\u1ee3c kh\u00f4ng nucleoside th\u1ebf h\u1ec7 \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m vi r\u00fat g\u00e2y suy gi\u1ea3m mi\u1ec5n d\u1ecbch \u1edf ng\u01b0\u1eddi (HIV) lo\u1ea1i 1 ho\u1eb7c \u0111\u1ec3 ng\u0103n ng\u1eeba s\u1ef1 l\u00e2y lan c\u1ee7a HIV.<\/span><\/li>\n<li><span style=\"font-weight: 400\">C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m SaVi (Savipharm) l\u00e0 th\u01b0\u01a1ng hi\u1ec7u h\u00e0ng \u0111\u1ea7u trong l\u0129nh v\u1ef1c s\u1ea3n xu\u1ea5t, ph\u00e2n ph\u1ed1i D\u01b0\u1ee3c ph\u1ea9m t\u1ea1i Vi\u1ec7t Nam th\u00e0nh l\u1eadp t\u1eeb n\u0103m 2005, \u0111\u1ea1t ti\u00eau chu\u1ea9n GMP Ch\u00e2u\u00a0 u, Nh\u1eadt B\u1ea3n, \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m<\/span><\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 26.2093%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">L\u00e0 thu\u1ed1c k\u00ea \u0111\u01a1n, c\u1ea7n c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129, kh\u00f4ng \u0111\u01b0\u1ee3c t\u1ef1 \u00fd mua v\u00e0 s\u1eed d\u1ee5ng<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Thu\u1ed1c c\u00f3 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5, t\u01b0\u01a1ng t\u00e1c thu\u1ed1c c\u1ea7n tr\u00e1nh, n\u00ean \u0111\u1ecdc k\u1ef9 h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng tr\u01b0\u1edbc khi d\u00f9ng AgiFovir- F<\/span><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3 Anchalee Avihingsanon v\u00e0 c\u1ed9ng s\u1ef1 (\u0110\u0103ng ng\u00e0y 13 th\u00e1ng 6 n\u0103m 2017), <em>Efficacy and safety of a once-daily single-tablet regimen of tenofovir, lamivudine, and efavirenz assessed at 144 weeks among antiretroviral-na\u00efve and experienced HIV-1-infected Thai adults. <\/em>Truy c\u1eadp ng\u00e0y 3 th\u00e1ng 10 n\u0103m 2023 t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28627427\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28627427\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1c gi\u1ea3 B\u00e1rbara Costa, Nuno Vale (\u0110\u0103ng ng\u00e0y 31 th\u00e1ng 12 n\u0103m 2022), <em>Efavirenz: History, Development and Future.<\/em>Truy c\u1eadp ng\u00e0y 3 th\u00e1ng 10 n\u0103m 2023 t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36671473\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36671473\/<\/span><\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c AgiFovir- F thu\u1ed9c nh\u00f3m thu\u1ed1c kh\u00e1ng retrovirus ch\u1ee9a tenofovir disoproxil fumarat, lamivudin v\u00e0 efavirenz ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb cho ng\u01b0\u1eddi l\u1edbn b\u1ecb nhi\u1ec5m HIV-1<\/p>\n","protected":false},"author":490,"featured_media":47250,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-47246","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/47246","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=47246"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/47250"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=47246"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=47246"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=47246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}