{"id":46787,"date":"2023-10-03T16:43:58","date_gmt":"2023-10-03T09:43:58","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=46787"},"modified":"2025-07-24T14:02:06","modified_gmt":"2025-07-24T07:02:06","slug":"mycazole","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/mycazole\/","title":{"rendered":"Mycazole"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Mycazole<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi RAFARM S.A., \u0111\u0103ng k\u00fd b\u1edfi C\u00f4ng ty TNHH D\u01b0\u1ee3c ph\u1ea9m Lamda c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-22092-19.<\/b><\/p>\n

Mycazole l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n
Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n
Thu\u1ed1c Mycazole<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n
\n
Fluconazol h\u00e0m l\u01b0\u1ee3ng 200mg<\/span><\/li>\n
C\u00e1c t\u00e1 d\u01b0\u1ee3c kh\u00e1c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/span><\/li>\n<\/ul>\n
D\u1ea1ng b\u00e0o ch\u1ebf: vi\u00ean nang c\u1ee9ng<\/span><\/p>\n
Tr\u00ecnh b\u00e0y<\/span><\/h3>\n
S\u0110K: VN-22092-19<\/span><\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: h\u1ed9p c\u00f3 1 v\u1ec9 x 7 vi\u00ean nang<\/span><\/p>\n
Xu\u1ea5t x\u1ee9: Hy L\u1ea1p<\/span><\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Mycazole<\/span><\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng\u00a0<\/span><\/h3>\n
Fluconazol<\/strong> l\u00e0 thu\u1ed1c ch\u1ed1ng n\u1ea5m thu\u1ed9c nh\u00f3m thu\u1ed1c t\u1ed5ng h\u1ee3p triazol v\u00e0 ho\u1ea1t \u0111\u1ed9ng ch\u1ee7 y\u1ebfu nh\u1edd s\u1ef1 \u1ee9c ch\u1ebf dimethyl h\u00f3a 14 alphanosterol qua trung gian cytochrom P450.. S\u1ef1 t\u00edch l\u0169y c\u00e1c 14 alpha-methyl sterol c\u00f3 li\u00ean quan v\u1edbi s\u1ef1 m\u1ea5t ergosterol \u1edf m\u00e0ng t\u1ebf b\u00e0o n\u1ea5m c\u00f3 th\u1ec3 l\u00e0 nguy\u00ean nh\u00e2n c\u1ee7a t\u00e1c d\u1ee5ng ch\u1ed1ng n\u1ea5m c\u1ee7a fluconazol. Fluconazol ch\u1ecdn l\u1ecdc h\u01a1n \u0111\u1ed1i v\u1edbi enzym cytochrom P450 \u1edf n\u1ea5m h\u01a1n h\u1ec7 enzym cytochrome P450 \u1edf c\u00e1c \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa.<\/span><\/p>\n
\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n\n\n\n\n\n\n
H\u1ea5p thu<\/span><\/td>\n Fluconazol h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 sinh kh\u1ea3 d\u1ee5ng to\u00e0n th\u00e2n tr\u00ean 90% n\u1ed3ng \u0111\u1ed9 \u0111\u1ea1t \u0111\u01b0\u1ee3c sau khi d\u00f9ng \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch. H\u1ea5p thu \u0111\u01b0\u1eddng u\u1ed1ng kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n.<\/span><\/td>\n<\/tr>\n
Ph\u00e2n b\u1ed1<\/span><\/td>\n Fluconazol x\u00e2m nh\u1eadp t\u1ed1t v\u00e0o t\u1ea5t c\u1ea3 c\u00e1c d\u1ecbch c\u01a1 th\u1ec3. N\u1ed3ng \u0111\u1ed9 fluconazol trong n\u01b0\u1edbc b\u1ecdt v\u00e0 \u0111\u1eddm t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft thanh. \u1ede c\u00e1c b\u1ec7nh nh\u00e2n vi\u00eam m\u00e0ng n\u00e3o do n\u1ea5m n\u1ed3ng \u0111\u1ed9 fluconazol trong d\u1ecbch n\u00e3o t\u1ee7y kho\u1ea3ng 80% so v\u1edbi n\u1ed3ng \u0111\u1ed9 trong m\u00e1u<\/span><\/td>\n<\/tr>\n
Chuy\u1ec3n h\u00f3a<\/span><\/td>\n Fluconazol b\u1ecb chuy\u1ec3n h\u00f3a \u1edf m\u1ee9c \u0111\u1ed9 nh\u1eb9<\/span><\/td>\n<\/tr>\n
Th\u1ea3i tr\u1eeb<\/span><\/td>\n Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn, kho\u1ea3ng 80% li\u1ec1u d\u00f9ng xu\u1ea5t hi\u1ec7n trong n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Thu\u1ed1c Mycazole \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n
Fluconazol \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m \u1edf ng\u01b0\u1eddi l\u1edbn trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/span><\/p>\n
\n
Vi\u00eam m\u00e0ng n\u00e3o do Cryptococcus.<\/span><\/li>\n
Nhi\u1ec5m n\u1ea5m s\u00e2u Coccidioidomycosis.\u00a0<\/span><\/li>\n
Nhi\u1ec5m Candida x\u00e2m l\u1ea5n.<\/span><\/li>\n
Nhi\u1ec5m Candida ni\u00eam m\u1ea1c bao g\u1ed3m: Candida mi\u1ec7ng-th\u1ef1c qu\u1ea3n, th\u1ef1c qu\u1ea3n, Candida ni\u1ec7u v\u00e0 Candida ni\u00eam m\u1ea1c da m\u1ea1n t\u00ednh.<\/span><\/li>\n
Nhi\u1ec5m n\u1ea5m Candida mi\u1ec7ng m\u00e3n t\u00ednh (vi\u00eam mi\u1ec7ng do r\u0103ng gi\u1ea3) n\u1ebfu v\u1ec7 sinh r\u0103ng mi\u1ec7ng ho\u1eb7c \u0111i\u1ec1u tr\u1ecb t\u1ea1i ch\u1ed7 kh\u00f4ng s\u1ea1ch.<\/span><\/li>\n
Nhi\u1ec5m Candida \u00e2m \u0111\u1ea1o, c\u1ea5p t\u00ednh ho\u1eb7c t\u00e1i ph\u00e1t khi c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb t\u1ea1i ch\u1ed7 kh\u00f4ng ph\u00f9 h\u1ee3p.<\/span><\/li>\n
Vi\u00eam quy \u0111\u1ea7u do Candida khi bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb t\u1ea1i ch\u1ed7 kh\u00f4ng ph\u00f9 h\u1ee3p.<\/span><\/li>\n
C\u00e1c b\u1ec7nh n\u1ea5m da bao g\u1ed3m n\u1ea5m b\u00e0n ch\u00e2n, n\u1ea5m da to\u00e0n th\u00e2n, n\u1ea5m da \u0111\u00f9i, nhi\u1ec5m n\u1ea5m da \u0111a s\u1eafc v\u00e0 n\u1ea5m da Candida khi \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb to\u00e0n th\u00e2n.<\/span><\/li>\n
N\u1ea5m da unguinium (n\u1ea5m m\u00f3ng) khi c\u00e1c t\u00e1c nh\u00e2n kh\u00e1c kh\u00f4ng ph\u00f9 h\u1ee3p<\/span><\/li>\n<\/ul>\n
Fluconazol c\u00f2n \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u1edf ng\u01b0\u1eddi l\u1edbn \u0111\u1ec3 d\u1ef1 ph\u00f2ng:<\/span><\/p>\n
\n
T\u00e1i ph\u00e1t vi\u00eam n\u00e3o do Cryptococcus \u0111\u1ed1i v\u1edbi c\u00e1c b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 t\u00e1i ph\u00e1t cao.<\/span><\/li>\n
T\u00e1i ph\u00e1t nhi\u1ec5m Candida th\u1ef1c qu\u1ea3n – mi\u1ec7ng v\u00e0 th\u1ef1c qu\u1ea3n \u1edf c\u00e1c b\u1ec7nh nh\u00e2n nhi\u1ec5m HIV, nh\u1eefng ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 t\u00e1i ph\u00e1t.<\/span><\/li>\n
Gi\u1ea3m t\u00e1i ph\u00e1t nhi\u1ec5m Candida \u00e2m \u0111\u1ea1o (4 \u0111\u1ee3t tr\u1edf l\u00ean\/ n\u0103m).<\/span><\/li>\n
D\u1ef1 ph\u00f2ng nhi\u1ec5m Candida \u1edf b\u1ec7nh nh\u00e2n gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh k\u00e9o d\u00e0i ( b\u1ec7nh nh\u00e2n ung th\u01b0 m\u00e1u \u0111ang h\u00f3a tr\u1ecb li\u1ec7u, b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c).<\/span><\/li>\n<\/ul>\n
C\u00f3 th\u1ec3 ch\u1ec9 \u0111\u1ecbnh fluconazol tr\u01b0\u1edbc khi c\u00f3 k\u1ebft qu\u1ea3 v\u1ec1 nu\u00f4i c\u1ea5y vi tr\u00f9ng ho\u1eb7c c\u00e1c x\u00e9t nghi\u1ec7m kh\u00e1c, khi c\u00f3 k\u1ebft qu\u1ea3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh s\u1eed d\u1ee5ng \u0111\u00fang thu\u1ed1c.<\/span><\/p>\n
Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Mycazole<\/span><\/h2>\n
\n
\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m Cryptococcoccus:\u00a0<\/span><\/li>\n<\/ul>\n
Vi\u00eam m\u00e0ng n\u00e3o do Cryptococcoccus: Ng\u00e0y \u0111\u1ea7u 400mg\/ ng\u00e0y, sau \u0111\u00f3 200 – 400mg\/ ng\u00e0y. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb \u00edt nh\u1ea5t 6 – 8 tu\u1ea7n. Trong tr\u01b0\u1eddng h\u1ee3p \u0111e d\u1ecda t\u00ednh m\u1ea1ng c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u \u0111\u1ebfn 800 mg\/ng\u00e0y<\/span><\/p>\n
\u0110i\u1ec1u tr\u1ecb duy tr\u00ec \u0111\u1ec3 ng\u0103n t\u00e1i ph\u00e1t vi\u00eam m\u00e0ng n\u00e3o do Cryptococcus \u1edf c\u00e1c b\u1ec7nh nh\u00e2n nguy c\u01a1 t\u00e1i ph\u00e1t cao: li\u1ec1u 200mg\/ ng\u00e0y. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb: kh\u00f4ng th\u1eddi h\u1ea1n<\/span><\/p>\n
\n
\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m s\u00e2u Coccidioidomycosis: 200- 400mg\/ ng\u00e0y. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb t\u1eeb 11 – 24 th\u00e1ng ho\u1eb7c l\u00e2u h\u01a1n t\u00f9y t\u00ecnh tr\u1ea1ng b\u1ec7nh nh\u00e2n. C\u00f3 th\u1ec3 t\u0103ng li\u1ec1u t\u1edbi 800mg\/ ng\u00e0y \u1edf m\u1ed9t s\u1ed1 nhi\u1ec5m khu\u1ea9n nh\u01b0 b\u1ec7nh m\u00e0ng n\u00e3o<\/span><\/li>\n
\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m Candida x\u00e2m l\u1ea5n: Ng\u00e0y \u0111\u1ea7u 800mg\/ ng\u00e0y, sau \u0111\u00f3 d\u00f9ng li\u1ec1u 400mg\/ ng\u00e0y. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb\u00a0 2 tu\u1ea7n sau khi c\u00f3 k\u1ebft qu\u1ea3 nu\u00f4i c\u1ea5y \u00e2m t\u00ednh v\u00e0 gi\u1ea3i quy\u1ebft c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng candida huy\u1ebft.<\/span><\/li>\n
\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m Candida ni\u00eam m\u1ea1c:<\/span><\/li>\n<\/ul>\n
Nhi\u1ec5m Candida mi\u1ec7ng – th\u1ef1c qu\u1ea3n\/ th\u1ef1c qu\u1ea3n: Ng\u00e0y \u0111\u1ea7u 200 – 400mg\/ ng\u00e0y, sau \u0111\u00f3 100 – 200mg\/ ng\u00e0y. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb Candida mi\u1ec7ng – th\u1ef1c qu\u1ea3n 7 – 21 ng\u00e0y cho t\u1edbi khi thuy\u00ean gi\u1ea3m, c\u00f3 th\u1ec3 d\u00e0i h\u01a1n \u1edf c\u00e1c b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch n\u1eb7ng. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb Candida th\u1ef1c qu\u1ea3n 14 – 30 ng\u00e0y cho t\u1edbi khi thuy\u00ean gi\u1ea3m, c\u00f3 th\u1ec3 d\u00e0i h\u01a1n \u1edf c\u00e1c b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch n\u1eb7ng.<\/span><\/p>\n
Nhi\u1ec5m Candida ni\u1ec7u: 200- 400mg\/ ng\u00e0y. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb t\u1eeb 7 – 21 ng\u00e0y cho t\u1edbi khi thuy\u00ean gi\u1ea3m, c\u00f3 th\u1ec3 d\u00e0i h\u01a1n \u1edf c\u00e1c b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch n\u1eb7ng.\u00a0<\/span><\/p>\n
Nhi\u1ec5m Candida mi\u1ec7ng m\u1ea1n t\u00ednh: li\u1ec1u 50mg\/ ng\u00e0y trong 14 ng\u00e0y<\/span><\/p>\n
Nhi\u1ec5m Candida da m\u1ea1n t\u00ednh: 50 – 100mg\/ ng\u00e0y.\u00a0 Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb 28 ng\u00e0y cho t\u1edbi khi thuy\u00ean gi\u1ea3m, c\u00f3 th\u1ec3 d\u00e0i h\u01a1n \u1edf c\u00e1c b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch n\u1eb7ng.<\/span><\/p>\n
\n
T\u00e1i ph\u00e1t nhi\u1ec5m Candida ni\u00eam m\u1ea1c \u1edf c\u00e1c b\u1ec7nh nh\u00e2n nhi\u1ec5m HIV, nh\u1eefng ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 t\u00e1i ph\u00e1t cao: Nhi\u1ec5m Candida mi\u1ec7ng – th\u1ef1c qu\u1ea3n d\u00f9ng li\u1ec1u 100 – 200mg\/ ng\u00e0y ho\u1eb7c 200mg x 3 l\u1ea7n\/ tu\u1ea7n, Candida th\u1ef1c qu\u1ea3n d\u00f9ng li\u1ec1u 100 – 200mg\/ ng\u00e0y ho\u1eb7c 200mg 3 l\u1ea7n\/ tu\u1ea7n. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb v\u00f4 h\u1ea1n \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch m\u1ea1n t\u00ednh.<\/span><\/li>\n
\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m Candida ni\u1ec7u \u0111\u1ea1o:\u00a0<\/span><\/li>\n<\/ul>\n
Nhi\u1ec5m Candida \u00e2m \u0111\u1ea1o c\u1ea5p v\u00e0 vi\u00eam quy \u0111\u1ea7u do Candida: \u0111\u01a1n li\u1ec1u 150mg<\/span><\/p>\n
\u0110i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng t\u00e1i ph\u00e1t Candida \u00e2m \u0111\u1ea1o (4 \u0111\u1ee3t ho\u1eb7c nhi\u1ec1u h\u01a1n 1 n\u0103m): 150mg c\u00e1ch nhau 3 ng\u00e0y, t\u1ed5ng 3 li\u1ec1u (ng\u00e0y 1, 4, v\u00e0 7) sau \u0111\u00f3 duy tr\u00ec 150mg\/ l\u1ea7n\/ tu\u1ea7n trong v\u00f2ng 6 th\u00e1ng<\/span><\/p>\n
\n
\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m da:\u00a0<\/span><\/li>\n<\/ul>\n
N\u1ea5m b\u00e0n ch\u00e2n (tinea pedis), n\u1ea5m da to\u00e0n th\u00e2n (tinea corporis), n\u1ea5m da \u0111\u00f9i (tinea cruris) v\u00e0 nhi\u1ec5m candida da: 150mg\/ l\u1ea7n\/ tu\u1ea7n ho\u1eb7c 50mg\/ l\u1ea7n\/ ng\u00e0y , \u0111i\u1ec1u tr\u1ecb trong 2 \u0111\u1ebfn 4 tu\u1ea7n, n\u1ea5m b\u00e0n ch\u00e2n c\u00f3 th\u1ec3 \u0111i\u1ec1u tr\u1ecb trong 6 tu\u1ea7n<\/span><\/p>\n
N\u1ea5m da \u0111a s\u1eafc: 300 – 400mg\/ l\u1ea7n\/ tu\u1ea7n trong 1 – 3 tu\u1ea7n ho\u1eb7c 50mg\/ l\u1ea7n\/ ng\u00e0y trong 2 – 4 tu\u1ea7n<\/span><\/p>\n
N\u1ea5m da unguinium (n\u1ea5m m\u00f3ng): 150mg\/ l\u1ea7n\/ tu\u1ea7n cho t\u1edbi khi thay m\u00f3ng m\u1edbi kh\u00f4ng b\u1ecb nhi\u1ec5m n\u1ea5m.<\/span><\/p>\n
\n
D\u1ef1 ph\u00f2ng nhi\u1ec5m Candida \u1edf b\u1ec7nh nh\u00e2n gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh k\u00e9o d\u00e0i: 200 – 400mg\/ ng\u00e0y, b\u1eaft \u0111\u1ea7u t\u1eeb v\u00e0i ng\u00e0y tr\u01b0\u1edbc \u0111\u1ee3t kh\u1edfi ph\u00e1t gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh v\u00e0 ti\u1ebfp t\u1ee5c 7 ng\u00e0y sau khi ph\u1ee5c h\u1ed3i, sau khi s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u trung t\u00ednh t\u0103ng l\u00ean tr\u00ean 1000\/mm3<\/span><\/li>\n<\/ul>\n
C\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t:\u00a0<\/span><\/p>\n\n\n\n\n\n\n
Ng\u01b0\u1eddi cao tu\u1ed5i<\/span><\/td>\n \u0110i\u1ec1u ch\u1ec9nh li\u1ec1u d\u1ef1a tr\u00ean ch\u1ee9c n\u0103ng th\u1eadn.<\/span><\/td>\n<\/tr>\n
Suy th\u1eadn<\/span><\/td>\n Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u khi d\u00f9ng \u0111\u01a1n li\u1ec1u. \u1ede c\u00e1c b\u1ec7nh nh\u00e2n (bao g\u1ed3m c\u1ea3 tr\u1ebb em) suy th\u1eadn, d\u00f9ng fluconazol \u0111a li\u1ec1u, li\u1ec1u kh\u1edfi \u0111\u1ea7u l\u00e0 50 \u2013 400 mg d\u1ef1a tr\u00ean li\u1ec1u khuy\u1ebfn c\u00e1o h\u00e0ng ng\u00e0y cho t\u1eebng ch\u1ec9 \u0111\u1ecbnh. Sau li\u1ec1u kh\u1edfi \u0111\u1ea7u d\u00f9ng li\u1ec1u h\u00e0ng ng\u00e0y theo b\u00e1c s\u0129 ch\u1ec9 \u0111\u1ecbnh, b\u1ec7nh nh\u00e2n th\u1ea9m ph\u00e2n th\u01b0\u1eddng xuy\u00ean d\u00f9ng li\u1ec1u 100% so v\u1edbi li\u1ec1u khuy\u1ebfn c\u00e1o sau m\u1ed7i l\u1ea7n th\u1ea9m ph\u00e2n, b\u1ec7nh nh\u00e2n kh\u00f4ng th\u1ea9m ph\u00e2n gi\u1ea3m li\u1ec1u theo \u0111\u1ed9 thanh th\u1ea3i creaninin.<\/span><\/td>\n<\/tr>\n
Suy gan<\/span><\/td>\n Th\u1eadn tr\u1ecdng khi d\u00f9ng fluconazol \u1edf b\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng gan<\/span><\/td>\n<\/tr>\n
Tr\u1ebb em<\/span><\/td>\n Kh\u00f4ng \u0111\u01b0\u1ee3c v\u01b0\u1ee3t qu\u00e1 li\u1ec1u t\u1ed1i \u0111a 400 mg\/ng\u00e0y. V\u1edbi nhi\u1ec5m khu\u1ea9n t\u01b0\u01a1ng \u0111\u01b0\u01a1ng \u1edf ng\u01b0\u1eddi l\u1edbn, th\u1eddi gian \u0111i\u1ec1u tr\u1ecb \u0111\u01b0\u1ee3c d\u1ef1a tr\u00ean \u0111\u00e1p \u1ee9ng l\u00e2m s\u00e0ng v\u00e0 n\u1ea5m h\u1ecdc. Fluconazol \u0111\u01b0\u1ee3c d\u00f9ng d\u1ea1ng \u0111\u01a1n li\u1ec1u h\u00e0ng ng\u00e0y theo ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129 t\u00f9y t\u1eebng tr\u01b0\u1eddng h\u1ee3p tr\u1ebb s\u01a1 sinh \u0111\u1ee7 th\u00e1ng, tr\u1ebb s\u01a1 sinh, tr\u1ebb m\u1edbi bi\u1ebft \u0111i, tr\u1ebb em v\u00e0 tr\u1ebb v\u1ecb th\u00e0nh ni\u00ean t\u1eeb 0 \u0111\u1ebfn 17 tu\u1ed5i<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Mycazole trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n
Kh\u00f4ng d\u00f9ng Mycazole 200mg<\/strong> trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p:<\/p>\n
\n
Qu\u00e1 m\u1eabn v\u1edbi fluconazol, nh\u00f3m azol, ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/span><\/li>\n
D\u00f9ng terfenadin \u1edf b\u1ec7nh nh\u00e2n d\u00f9ng fluconazol \u0111a li\u1ec1u 400 mg\/ng\u00e0y ho\u1eb7c cao h\u01a1n d\u1ef1a tr\u00ean k\u1ebft qu\u1ea3 c\u1ee7a m\u1ed9t nghi\u00ean c\u1ee9u t\u01b0\u01a1ng t\u00e1c thu\u1ed1c khi d\u00f9ng \u0111a li\u1ec1u.\u00a0<\/span><\/li>\n
D\u00f9ng c\u00e1c thu\u1ed1c g\u00e2y k\u00e9o d\u00e0i kho\u1ea3ng QT, b\u1ecb chuy\u1ec3n h\u00f3a qua cytochrom P450 (CYP) 3A4 ( cisaprid, astemizol, pimozid, quinidin, amiodaron v\u00e0 erythromycin )\u00a0<\/span><\/li>\n<\/ul>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Mycazole<\/span><\/h2>\n
Th\u1eadn tr\u1ecdng<\/span><\/h3>\n
\n
Fluconazol \u0111i\u1ec1u tr\u1ecb n\u1ea5m da \u0111\u1ea7u \u1edf tr\u1ebb em kh\u00f4ng t\u1ed1t h\u01a1n so v\u1edbi griseofulvin v\u00e0 t\u1ec9 l\u1ec7 th\u00e0nh c\u00f4ng l\u00e0 d\u01b0\u1edbi 20%. Do \u0111\u00f3, kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng cho n\u1ea5m da \u0111\u1ea7u (tinea captitis).<\/span><\/li>\n
Hi\u1ec7u qu\u1ea3 c\u1ee7a fluconazol trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m Cryptococcus \u1edf nh\u1eefng v\u1ecb tr\u00ed kh\u00e1c ( ph\u1ed5i, da) r\u1ea5t \u00edt, h\u1ea1n ch\u1ebf khuy\u1ebfn c\u00e1o k\u00ea \u0111\u01a1n.<\/span><\/li>\n
Hi\u1ec7u c\u1ee7a c\u1ee7a fluconazol trong \u0111i\u1ec1u tr\u1ecb c\u00e1c d\u1ea1ng n\u1ea5m s\u00e2u nh\u01b0 Paracoccidioidomycosis, lymphocutaneous sporotrichosis, histoplasmosis r\u1ea5t \u00edt, h\u1ea1n ch\u1ebf khuy\u1ebfn c\u00e1o k\u00ea \u0111\u01a1n.<\/span><\/li>\n
Th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 xu\u1ea5t huy\u1ebft, r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan, th\u1eadn.<\/span><\/li>\n
Ketoconazol g\u00e2y suy th\u01b0\u1ee3ng th\u1eadn, m\u1eb7c d\u00f9 hi\u1ebfm nh\u01b0ng c\u00f3 th\u1ec3 g\u1eb7p \u1edf fluconazol. Suy th\u01b0\u1ee3ng th\u1eadn c\u0169ng li\u00ean quan \u0111\u1ebfn vi\u1ec7c d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi prednisone\u00a0<\/span><\/li>\n
Fluconazol c\u00f3 th\u1ec3 li\u00ean quan \u0111\u1ebfn c\u00e1c tr\u01b0\u1eddng h\u1ee3p \u0111\u1ed9c t\u00ednh tr\u00ean gan hi\u1ebfm g\u1eb7p (t\u1eed vong) ch\u1ee7 y\u1ebfu \u1edf b\u1ec7nh nh\u00e2n c\u00f3 t\u00ecnh tr\u1ea1ng b\u1ec7nh nghi\u00eam tr\u1ecdng, c\u00e1c b\u1ec7nh nh\u00e2n ph\u00e1t hi\u1ec7n b\u1ea5t th\u01b0\u1eddng trong c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ee9c n\u0103ng gan ph\u1ea3i \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd v\u1ec1 s\u1ef1 t\u1ed5n th\u01b0\u01a1ng gan.<\/span><\/li>\n
B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c th\u00f4ng b\u00e1o v\u1ec1 c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a t\u00e1c \u0111\u1ed9ng tr\u00ean gan nghi\u00eam tr\u1ecdng (suy nh\u01b0\u1ee3c c\u01a1 th\u1ec3, ch\u00e1n \u0103n, bu\u1ed3n n\u00f4n, n\u00f4n, v\u00e0ng da). Khi g\u1eb7p tri\u1ec7u ch\u1ee9ng ph\u1ea3i d\u1eebng fluconazol v\u00e0 b\u00e1o ngay cho b\u00e1c s\u0129 \u0111\u1ec3 d\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb k\u1ecbp th\u1eddi<\/span><\/li>\n
Fluconazol k\u00e9o d\u00e0i kho\u1ea3ng QT tr\u00ean \u0111i\u1ec7n t\u00e2m \u0111\u1ed3 \u1edf b\u1ec7nh nh\u00e2n \u1ed1m n\u1eb7ng v\u00e0 c\u00f3 nhi\u1ec1u y\u1ebfu t\u1ed1 nguy c\u01a1 nh\u01b0 b\u1ec7nh tim c\u1ea5u tr\u00fac, r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi.<\/span><\/li>\n
Kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c g\u00e2y k\u00e9o d\u00e0i kho\u1ea3ng QT v\u00e0 chuy\u1ec3n h\u00f3a qua h\u1ec7 cytochrom P450 (CYP) 3A4.<\/span><\/li>\n
Halofantrin g\u00e2y k\u00e9o d\u00e0i kho\u1ea3ng QT \u1edf li\u1ec1u \u0111i\u1ec1u tr\u1ecb khuy\u1ebfn c\u00e1o v\u00e0 l\u00e0 c\u01a1 ch\u1ea5t c\u1ee7a CYP3A4. Kh\u00f4ng d\u00f9ng \u0111\u1ed3ng th\u1eddi fluconazol v\u00e0 halofantrin.<\/span><\/li>\n
C\u00e1c b\u1ec7nh nh\u00e2n AIDS c\u00f3 xu h\u01b0\u1edbng g\u1eb7p ph\u1ea3i c\u00e1c ph\u1ea3n \u1ee9ng tr\u00ean da n\u1eb7ng. N\u1ebfu c\u00f3 ph\u00e1t ban xu\u1ea5t hi\u1ec7n \u1edf c\u00e1c b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb n\u1ea5m b\u1ec1 m\u1eb7t nghi do fluconazol, c\u1ea7n ng\u1eebng thu\u1ed1c. B\u1ec7nh nh\u00e2n nhi\u1ec5m n\u1ea5m x\u00e2m l\u1ea5n\/ to\u00e0n th\u00e2n xu\u1ea5t hi\u1ec7n ph\u00e1t ban c\u1ea7n theo d\u00f5i ch\u1eb7t v\u00e0 ng\u1eebng fluconazol khi xu\u1ea5t hi\u1ec7n b\u1ecdng n\u01b0\u1edbc ho\u1eb7c h\u1ed3ng ban \u0111a d\u1ea1ng.<\/span><\/li>\n
C\u00e1c b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb b\u1eb1ng fluconazol \u0111ang \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c c\u00f3 kho\u1ea3ng \u0111i\u1ec1u tr\u1ecb nh\u1ecf b\u1ecb chuy\u1ec3n h\u00f3a b\u1edfi CYP2C9, CYP2C19 v\u00e0 CYP3A4 c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i th\u1eadn tr\u1ecdng.<\/span><\/li>\n
C\u1ea7n theo d\u00f5i th\u1eadn tr\u1ecdng khi d\u00f9ng \u0111\u1ed3ng th\u1eddi fluconazol li\u1ec1u 400 mg\/ng\u00e0y v\u1edbi terfenadin.<\/span><\/li>\n
Mycazole c\u00f3 ch\u1ee9a lactose n\u00ean kh\u00f4ng d\u00f9ng \u1edf b\u1ec7nh nh\u00e2n c\u00f3 v\u1ea5n \u0111\u1ec1 di truy\u1ec1n hi\u1ebfm g\u1eb7p v\u1ec1 kh\u00f4ng dung n\u1ea1p galactose, thi\u1ebfu Lapp lactase ho\u1eb7c k\u00e9m h\u1ea5p thu glucose-galactose<\/span><\/li>\n<\/ul>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/h3>\n\n\n\n\n\n
Hay g\u1eb7p<\/span><\/td>\n \u0111au \u0111\u1ea7u, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, n\u00f4n, t\u0103ng alanine aminotransferase, t\u0103ng aspartate aminotransferase, phosphatase ki\u1ec1m trong m\u00e1u v\u00e0 ban \u0111\u1ecf.<\/span><\/td>\n<\/tr>\n
\u00cdt g\u1eb7p\u00a0<\/span><\/td>\n Thi\u1ebfu m\u00e1u, gi\u1ea3m th\u00e8m \u0103n, bu\u1ed3n ng\u1ee7, m\u1ea5t ng\u1ee7, \u0111\u1ed9ng kinh, m\u1ea5t c\u1ea3m gi\u00e1c, ch\u00f3ng m\u1eb7t, r\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c, t\u00e1o b\u00f3n, kh\u00f3 ti\u00eau, \u0111\u1ea7y h\u01a1i, kh\u00f4 mi\u1ec7ng, \u1ee9 m\u1eadt, v\u00e0ng da, t\u0103ng bilirubin, h\u1ed3ng ban nhi\u1ec5m s\u1eafc, m\u00e0y \u0111ay, ng\u1ee9a, t\u0103ng m\u1ed3 h\u00f4i, b\u1ec7nh c\u01a1, m\u1ec7t m\u1ecfi, kh\u00f3 ch\u1ecbu, suy nh\u01b0\u1ee3c, s\u1ed1t<\/span><\/td>\n<\/tr>\n
Hi\u1ebfm g\u1eb7p<\/span><\/td>\n Gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t, b\u1ea1ch c\u1ea7u, ti\u1ec3u c\u1ea7u, b\u1ea1ch c\u1ea7u trung t\u00ednh, ph\u1ea3n v\u1ec7, run, t\u0103ng cholesterol m\u00e1u, t\u0103ng triglyceride m\u00e1u, gi\u1ea3m kali, xo\u1eafn \u0111\u1ec9nh, k\u00e9o d\u00e0i kho\u1ea3ng QT, suy gan, ho\u1ea1i t\u1eed t\u1ebf b\u00e0o gan, vi\u00eam gan, t\u1ed5n th\u01b0\u01a1ng t\u1ebf b\u00e0o gan, ho\u1ea1i t\u1eed th\u01b0\u1ee3ng b\u00ec nhi\u1ec5m \u0111\u1ed9c, h\u1ed9i ch\u1ee9ng Stevens- Johnson, h\u1ed9i ch\u1ee9ng ngo\u1ea1i ban m\u1ee5n m\u1ee7 to\u00e0n th\u00e2n c\u1ea5p t\u00ednh (AGEP), vi\u00eam da tr\u00f3c v\u1ea3y, ph\u00f9 m\u1ea1ch, ph\u00f9 m\u1eb7t, r\u1ee5ng t\u00f3c<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Cisaprid<\/span><\/td>\n x\u1ea3y ra bi\u1ebfn c\u1ed1 v\u1ec1 tim m\u1ea1ch (xo\u1eafn \u0111\u1ec9nh), g\u00e2y t\u0103ng \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 cisaprid trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 k\u00e9o d\u00e0i kho\u1ea3ng QTc<\/span><\/td>\n<\/tr>\n
Terfenadin<\/span><\/td>\n k\u00e9o d\u00e0i kho\u1ea3ng QTc, l\u00e0m xu\u1ea5t hi\u1ec7n c\u00e1c r\u1ed1i lo\u1ea1n nh\u1ecbp tim nghi\u00eam tr\u1ecdng v\u00e0 t\u0103ng n\u1ed3ng \u0111\u1ed9 terfenadin trong huy\u1ebft t\u01b0\u01a1ng<\/span><\/td>\n<\/tr>\n
Astemizol<\/span><\/td>\n gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i Astemizol l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 astemizol trong huy\u1ebft t\u01b0\u01a1ng, c\u00f3 th\u1ec3 g\u00e2y k\u00e9o d\u00e0i kho\u1ea3ng QT<\/span><\/td>\n<\/tr>\n
Pimozid, Quinidin, Amiodaron<\/span><\/td>\n c\u00f3 th\u1ec3 d\u1eabn t\u1edbi \u1ee9c ch\u1ebf chuy\u1ec3n h\u00f3a pimozid, quinidin, Amiodaron l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 pimozid, quinidin, Amiodaron trong huy\u1ebft thanh d\u1eabn t\u1edbi k\u00e9o d\u00e0i kho\u1ea3ng QT<\/span><\/td>\n<\/tr>\n
Erythromycin, Halofantrin<\/span><\/td>\n c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh tr\u00ean tim (k\u00e9o d\u00e0i kho\u1ea3ng QT, xo\u1eafn \u0111\u1ec9nh) v\u00e0 \u0111\u1ed9t t\u1eed.<\/span><\/td>\n<\/tr>\n
Ivacaftor<\/span><\/td>\n d\u00f9ng \u0111\u1ed3ng th\u1eddi g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9 ivacaftor l\u00ean 3 l\u1ea7n, c\u1ea7n gi\u1ea3m li\u1ec1u Ivacaftor 150 mg x 1 l\u1ea7n\/ng\u00e0y\u00a0<\/span><\/td>\n<\/tr>\n
Rifampicin<\/span><\/td>\n gi\u1ea3m 25% AUC, th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a fluconazol ng\u1eafn h\u01a1n 20%, n\u00ean xem x\u00e9t t\u0103ng li\u1ec1u fluconazol.<\/span><\/td>\n<\/tr>\n
Hydrochlorothiazid<\/span><\/td>\n g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9 fluconazol trong huy\u1ebft t\u01b0\u01a1ng 40%<\/span><\/td>\n<\/tr>\n
C\u00e1c ch\u1ea5t b\u1ecb chuy\u1ec3n h\u00f3a b\u1edfi CYP2C9, CYP3A4 v\u00e0 CYP2C19<\/span><\/td>\n c\u00f3 th\u1ec3 t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft thanh c\u1ee7a c\u00e1c ch\u1ea5t b\u1ecb chuy\u1ec3n h\u00f3a b\u1edfi CYP2C9, CYP3A4 v\u00e0 CYP2C19<\/span><\/td>\n<\/tr>\n
C\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch\u00a0<\/span><\/td>\n c\u00f3 th\u1ec3 t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft thanh c\u1ee7a c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch (cyclosporin, everolimus, sirolimus v\u00e0 tacrolimus)<\/span><\/td>\n<\/tr>\n
Losartan<\/span><\/td>\n Fluconazol \u1ee9c ch\u1ebf s\u1ef1 chuy\u1ec3n h\u00f3a losartan th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh, b\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c ki\u1ec3m tra huy\u1ebft \u00e1p li\u00ean t\u1ee5c.<\/span><\/td>\n<\/tr>\n
Methadone, Rifabutin<\/span><\/td>\n c\u00f3 th\u1ec3 g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9 methadone, Rifabutin<\/span><\/td>\n<\/tr>\n
C\u00e1c thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid<\/span><\/td>\n Fluconazol l\u00e0m t\u0103ng Cmax v\u00e0 AUC c\u1ee7a flurbiprofen v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9 to\u00e0n th\u00e2n c\u1ee7a c\u00e1c NSAID b\u1ecb chuy\u1ec3n h\u00f3a b\u1edfi CYP2C9 (naproxen, lornoxicam, meloxicam, diclofenac)<\/span><\/td>\n<\/tr>\n
Phenytoin<\/span><\/td>\n Fluconazol \u1ee9c ch\u1ebf s\u1ef1 chuy\u1ec3n h\u00f3a qua gan c\u1ee7a phenytoin<\/span><\/td>\n<\/tr>\n
Prednisone<\/span><\/td>\n c\u00f3 th\u1ec3 g\u00e2y t\u0103ng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a CYP3A4 d\u1eabn t\u1edbi t\u0103ng chuy\u1ec3n h\u00f3a prednisone.<\/span><\/td>\n<\/tr>\n
Saquinavir, Voriconazol, Zidovudin<\/span><\/td>\n Fluconazol g\u00e2y t\u0103ng AUC v\u00e0 Cmax c\u1ee7a saquinavir, Voriconazol, Zidovudin<\/span><\/td>\n<\/tr>\n
C\u00e1c sulfonylurea<\/span><\/td>\n Fluconazol k\u00e9o d\u00e0i th\u1eddi gian b\u00e1n th\u1ea3i trong huy\u1ebft thanh c\u1ee7a c\u00e1c sulfonylurea d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng<\/span><\/td>\n<\/tr>\n
Theophylin<\/span><\/td>\n d\u1ec5 g\u00e2y ra ng\u1ed9 \u0111\u1ed9c Theophyllin<\/span><\/td>\n<\/tr>\n
Vinca alkaloid<\/span><\/td>\n c\u00f3 th\u1ec3 g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a c\u00e1c vinca alkaloid (vincristin, vinblastin) d\u1eabn t\u1edbi \u0111\u1ed9c t\u00ednh v\u1edbi c\u1ea7u th\u1eadn<\/span><\/td>\n<\/tr>\n
Vitamin A<\/span><\/td>\n c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n li\u00ean quan \u0111\u1ebfn h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng d\u01b0\u1edbi d\u1ea1ng gi\u1ea3 u n\u00e3o v\u00e0 bi\u1ebfn m\u1ea5t sau khi ng\u1eebng fluconazol. C\u00f3 th\u1ec3 d\u00f9ng \u0111\u1ed3ng th\u1eddi nh\u01b0ng l\u01b0u \u00fd \u0111\u1ebfn t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n li\u00ean quan \u0111\u1ebfn th\u1ea7n kinh trung \u01b0\u01a1ng.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/span><\/h3>\n
\n
Ph\u1ee5 n\u1eef c\u00f3 thai:<\/span><\/li>\n<\/ul>\n
\u0110\u00e3 c\u00f3 nhi\u1ec1u b\u00e1o c\u00e1o v\u1ec1 b\u1ea5t th\u01b0\u1eddng b\u1ea9m sinh \u1edf tr\u1ebb c\u00f3 m\u1eb9 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb trong \u00edt nh\u1ea5t 3 th\u00e1ng v\u1edbi li\u1ec1u cao (400 \u2013 800 mg\/ng\u00e0y) trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m Coccidioidomycosis. C\u00e1c nghi\u00ean c\u1ee9u \u1edf \u0111\u1ed9ng v\u1eadt cho th\u1ea5y fluconazol g\u00e2y \u0111\u1ed9c t\u00ednh tr\u00ean sinh s\u1ea3n. D\u1eef li\u1ec7u t\u1eeb v\u00e0i tr\u0103m ph\u1ee5 n\u1eef mang thai \u0111i\u1ec1u tr\u1ecb b\u1eb1ng li\u1ec1u chu\u1ea9n (< 200 mg\/ng\u00e0y), d\u00f9ng \u0111\u01a1n li\u1ec1u ho\u1eb7c li\u1ec1u l\u1eb7p l\u1ea1i trong ba th\u00e1ng \u0111\u1ea7u kh\u00f4ng th\u1ea5y t\u0103ng nguy c\u01a1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n tr\u00ean tr\u1ebb.\u00a0<\/span><\/p>\n
V\u00ec v\u1eady Fluconazol \u1edf li\u1ec1u chu\u1ea9n v\u00e0 th\u1eddi gian \u0111i\u1ec1u tr\u1ecb ng\u1eafn kh\u00f4ng n\u00ean d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai tr\u1eeb khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft, Fluconazol li\u1ec1u cao v\u00e0\/ho\u1eb7c th\u1eddi gian \u0111i\u1ec1u tr\u1ecb d\u00e0i ng\u00e0y kh\u00f4ng d\u00f9ng \u1edf ph\u1ee5 n\u1eef c\u00f3 thai tr\u1eeb khi nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1ee3c coi l\u00e0 \u0111e d\u1ecda t\u00ednh m\u1ea1ng.<\/span><\/p>\n
\n
B\u00e0 m\u1eb9 cho con b\u00fa:<\/span><\/li>\n<\/ul>\n
Fluconazol qua \u0111\u01b0\u1ee3c h\u00e0ng r\u00e0o s\u1eefa m\u1eb9 v\u00e0 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 th\u1ea5p h\u01a1n trong huy\u1ebft t\u01b0\u01a1ng. M\u1eb9 c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c cho con b\u00fa sau khi d\u00f9ng li\u1ec1u \u0111\u01a1n fluconazol d\u01b0\u1edbi 200 mg, kh\u00f4ng khuy\u1ebfn c\u00e1o cho con b\u00fa sau khi d\u00f9ng li\u1ec1u l\u1eb7p l\u1ea1i ho\u1eb7c li\u1ec1u cao fluconazol.<\/span><\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n\n\n\n\n
Tri\u1ec7u ch\u1ee9ng<\/span><\/td>\n Qu\u00e1 li\u1ec1u fluconazol g\u00e2y \u1ea3o gi\u00e1c v\u00e0 hoang t\u01b0\u1edfng\u00a0<\/span><\/td>\n<\/tr>\n
X\u1eed tr\u00ed<\/span><\/td>\n \u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u1edbi c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 v\u00e0 r\u1eeda d\u1ea1 d\u00e0y n\u1ebfu c\u1ea7n thi\u1ebft.<\/span><\/p>\n
Fluconazol \u0111\u01b0\u1ee3c th\u1ea3i ph\u1ea7n l\u1edbn v\u00e0o n\u01b0\u1edbc ti\u1ec3u, do \u0111\u00f3 t\u0103ng b\u00e0i ni\u1ec7u c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u1ed1c \u0111\u1ed9 th\u1ea3i tr\u1eeb<\/span><\/p>\n
3 ti\u1ebfng th\u1ea9m ph\u00e2n m\u00e1u gi\u00fap l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng 50%.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Thu\u1ed1c Mycazole gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n
Thu\u1ed1c Mycazole hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n
Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Mycazole t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Mycazole nh\u01b0:\u00a0\u00a0<\/span><\/p>\n
\n
Fluconazol Stada 150mg<\/a> c\u00f3 ch\u1ee9a Fluconazole \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m Candida ngo\u00e0i da ho\u1eb7c ni\u00eam m\u1ea1c, nhi\u1ec5m n\u1ea5m to\u00e0n th\u00e2n g\u00e2y ra do 1 s\u1ed1 lo\u00e0i n\u1ea5m. Fluconazol Stada 150 mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty li\u00ean doanh TNHH Stada, 1 h\u1ed9p c\u00f3 1 vi\u00ean nang v\u00e0 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng v\u1edbi gi\u00e1 12,000\u0111.<\/span><\/li>\n
Flucomedil<\/a> c\u00f3 ch\u1ee9a Fluconazole \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m \u1edf mi\u1ec7ng, th\u1ef1c qu\u1ea3n, ti\u1ebft ni\u1ec7u,.. \u0111\u1eb7c bi\u1ec7t l\u00e0 nhi\u1ec5m n\u1ea5m \u1edf m\u00e0ng n\u00e3o do Cryptococcus neoformans. Flucomedil \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Medochemie., Ltd, 1 h\u1ed9p c\u00f3 1 vi\u00ean v\u00e0 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng v\u1edbi gi\u00e1 38,955\u0111.<\/span><\/li>\n<\/ul>\n
T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Mycazole?<\/span><\/h2>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/span><\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n
\n
\n
Thu\u1ed1c Mycazole b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean n\u00ean ti\u1ec7n l\u1ee3i, d\u1ec5 s\u1eed d\u1ee5ng, b\u1ea3o qu\u1ea3n, l\u01b0u tr\u1eef, v\u1eadn chuy\u1ec3n v\u00e0 mang theo<\/span><\/li>\n
Fluconazol c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng cho tr\u1ebb s\u01a1 sinh, tr\u1ebb s\u01a1 sinh thi\u1ebfu th\u00e1ng, tr\u1ebb t\u1eadp \u0111i, tr\u1ebb v\u1ecb th\u00e0nh ni\u00ean<\/span><\/li>\n
Fluconazol l\u00e0 m\u1ed9t ch\u1ea5t ch\u1ed1ng n\u1ea5m h\u1eefu \u00edch do h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng u\u1ed1ng, d\u1ec5 s\u1eed d\u1ee5ng, ph\u1ed5 t\u00e1c d\u1ee5ng kh\u00e1ng n\u1ea5m r\u1ed9ng.<\/span><\/li>\n
Fluconazole l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn thay th\u1ebf c\u00f3 gi\u00e1 tr\u1ecb cho c\u00e1c thu\u1ed1c kh\u00e1ng n\u1ea5m azole to\u00e0n th\u00e2n v\u00e0 trong \u00e2m \u0111\u1ea1o \u0111\u00e3 \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh n\u1ea5m candida \u00e2m \u0111\u1ea1o.<\/li>\n
Mycazole \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi RAFARM S.A., \u0111\u00e2y l\u00e0 c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m c\u00f3 uy t\u00edn \u1edf Hy L\u1ea1p, \u0111\u1ea3m b\u1ea3o ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m<\/li>\n<\/ul>\n<\/td>\n
\n
\n
Mycazole l\u00e0 thu\u1ed1c k\u00ea \u0111\u01a1n, c\u1ea7n c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129\u00a0<\/span><\/li>\n
Fluconazol c\u00f3 th\u1eddi gian \u0111i\u1ec1u tr\u1ecb d\u00e0i, ph\u1ea3i tu\u00e2n th\u1ee7 ch\u1ec9 \u0111\u1ecbnh, th\u1eddi gian \u0111i\u1ec1u tr\u1ecb c\u1ee7a b\u00e1c s\u0129, kh\u00f4ng \u0111\u01b0\u1ee3c t\u1ef1 \u00fd d\u1eebng thu\u1ed1c<\/span><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n
\n
H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c do B\u1ed9 y t\u1ebf, C\u1ee5c qu\u1ea3n l\u00fd D\u01b0\u1ee3c ph\u00ea duy\u1ec7t, t\u1ea3i b\u1ea3n PDF t\u1ea1i \u0111\u00e2y<\/a>\u00a0<\/span><\/li>\n
T\u00e1c gi\u1ea3 PB Agrawal v\u00e0 c\u1ed9ng s\u1ef1 (\u0110\u0103ng th\u00e1ng 11- 12 n\u0103m 1996), Fluconazole<\/em>. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 9 n\u0103m 2023 t\u1eeb <\/span>https:\/\/pubmed.ncbi.nlm.nih.gov\/10830059\/<\/span><\/a>\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
Mycazole l\u00e0 thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng \u0111i\u1ec1u tr\u1ecb n\u1ea5m h\u1ed3ng \u1edf ng\u01b0\u1eddi nhi\u1ec1u nh\u01b0 nhi\u1ec5m n\u1ea5m h\u1ed3ng canida mi\u1ec7ng, nhi\u1ec5m n\u1ea5m h\u1ed3ng canida \u00e2m \u0111\u1ea1o, nhi\u1ec5m n\u1ea5m h\u1ed3ng canida ni\u00eam m\u1ea1c.<\/p>\n","protected":false},"author":490,"featured_media":46793,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-46787","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/46787","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=46787"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/46793"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=46787"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=46787"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=46787"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}