{"id":45745,"date":"2023-09-29T16:26:16","date_gmt":"2023-09-29T09:26:16","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=45745"},"modified":"2025-07-24T14:02:16","modified_gmt":"2025-07-24T07:02:16","slug":"ravenell-625","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/ravenell-625\/","title":{"rendered":"Ravenell-62,5"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/ravenell-625\/\">Ravenell-62,5<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-31092-18.<\/strong><\/p>\n<h2>Ravenell-62,5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Thu\u1ed1c <strong>Ravenell-62,5<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Bosentan (d\u01b0\u1edbi d\u1ea1ng Bosentan monohydrat): 62,5 mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: H\u1ed9p 4 v\u1ec9 x 14 vi\u00ean\/v\u1ec9<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-31092-18<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 4 v\u1ec9 x 14 vi\u00ean\/v\u1ec9<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Ravenell-62,5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng ch\u00ednh c\u1ee7a <strong>Bosentan<\/strong> l\u00e0 \u1ee9c ch\u1ebf c\u00e1c th\u1ee5 th\u1ec3 endothelin (ET) A v\u00e0 B.<\/p>\n<p>Endothelin l\u00e0 m\u1ed9t ch\u1ea5t g\u1ed1c peptide \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00e1c t\u1ebf b\u00e0o m\u00f4 m\u1ea1ch m\u00e1u v\u00e0 c\u00f3 vai tr\u00f2 quan tr\u1ecdng trong \u0111i\u1ec1u ch\u1ec9nh s\u1ef1 co b\u00f3p v\u00e0 gi\u00e3n n\u1edf c\u1ee7a m\u1ea1ch m\u00e1u.<\/p>\n<p>Vi\u1ec7c \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 ETA gi\u00fap gi\u1ea3m s\u1ef1 co b\u00f3p m\u1ea1ch m\u00e1u, gi\u1ea3m c\u0103ng th\u1eb3ng tr\u00ean th\u00e0nh m\u1ea1ch v\u00e0 gi\u1ea3m kh\u00e1ng c\u1ef1 m\u1ea1ch m\u00e1u. \u0110i\u1ec1u n\u00e0y l\u00e0m gi\u1ea3m \u00e1p l\u1ef1c trong m\u1ea1ch m\u00e1u v\u00e0 gi\u1ea3m kh\u1ea3 n\u0103ng t\u0103ng \u00e1p ph\u1ed5i.<\/p>\n<p>Ngo\u00e0i ra, Bosentan c\u0169ng \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 ETB, d\u1eabn \u0111\u1ebfn gi\u1ea3m s\u1ea3n xu\u1ea5t Endothelin v\u00e0 ng\u0103n ch\u1eb7n c\u00e1c t\u00e1c \u0111\u1ed9ng c\u1ee7a n\u00f3 l\u00ean m\u1ea1ch m\u00e1u.<\/p>\n<p>T\u00f3m l\u1ea1i, Bosentan gi\u00fap c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh t\u0103ng \u00e1p ph\u1ed5i v\u00e0 c\u00e1c b\u1ec7nh tim m\u1ea1ch c\u00f3 li\u00ean quan.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a Bosentan kho\u1ea3ng 50%. Kh\u1ea3 n\u0103ng h\u1ea5p thu Bosentan kh\u00f4ng ph\u1ee5 thu\u1ed9c b\u1edfi th\u1ee9c \u0103n.<\/p>\n<p>Ph\u00e2n b\u1ed1: Bosentan c\u00f3 kh\u1ea3 n\u0103ng li\u00ean k\u1ebft cao v\u1edbi Albumin trong protein huy\u1ebft t\u01b0\u01a1ng. Ch\u1ec9 kho\u1ea3ng 2% Bosentan kh\u00f4ng li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Bosentan ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1edfi h\u1ec7 enzym gan, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c enzym CYP450, CYP2C9, v\u00e0 CYP3A4.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Bosentan v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a n\u00f3 \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua m\u1eadt, v\u00e0 n\u01b0\u1edbc ti\u1ec3u (3%).<\/p>\n<h2>Thu\u1ed1c Ravenell-62,5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Thu\u1ed1c Ravenell-62,5mg<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<p>Ng\u01b0\u1eddi b\u1ec7nh t\u0103ng \u00e1p l\u1ef1c ph\u1ed5i \u0111\u1ed9 III c\u1ea7n c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng g\u1eafng s\u1ee9c.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ec7nh t\u0103ng \u00e1p l\u1ef1c \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i ti\u00ean ph\u00e1t, g\u00e2y ra b\u1edfi x\u01a1 c\u1ee9ng b\u00ec ho\u1eb7c g\u00e2y ra b\u1edfi khuy\u1ebft t\u1eadt tim b\u1ea9m sinh.<\/p>\n<p>B\u1ec7nh nh\u00e2n x\u01a1 c\u1ee9ng b\u00ec b\u1ecb lo\u00e9t ng\u00f3n tay, ng\u00f3n ch\u00e2n.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Ravenell-62,5<\/h2>\n<p>Ng\u01b0\u1eddi l\u1edbn: Trong 4 tu\u1ea7n \u0111\u1ea7u, u\u1ed1ng s\u00e1ng 1 vi\u00ean v\u00e0 t\u1ed1i 1 vi\u00ean Ravenell-62,5. T\u1eeb tu\u1ea7n th\u1ee9 5 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ng\u00e0y 2 l\u1ea7n, m\u1ed7i l\u1ea7n 1 vi\u00ean <strong>Ravenell-125.\u00a0<\/strong>T\u00f9y v\u00e0o kh\u1ea3 n\u0103ng \u0111\u00e1p \u1ee9ng c\u1ee7a c\u01a1 th\u1ec3 m\u00e0 s\u1ebd c\u00f3 ch\u1ec9 \u0111\u1ecbnh ph\u00f9 h\u1ee3p c\u1ee7a b\u00e1c s\u0129.<\/p>\n<p>Tr\u1ebb em tr\u00ean 1 tu\u1ed5i: Li\u1ec1u d\u00f9ng t\u00ednh theo c\u00e2n n\u1eb7ng 2mg\/kg x 2 l\u1ea7n\/24 gi\u1edd.<\/p>\n<p>C\u00e1ch d\u00f9ng: U\u1ed1ng nguy\u00ean vi\u00ean thu\u1ed1c v\u1edbi n\u01b0\u1edbc, kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o b\u1eefa \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Ravenell-62,5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>M\u1eabn c\u1ea3m v\u1edbi Bosentan hay b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng gan suy gi\u1ea3m.<\/p>\n<p>N\u1eef gi\u1edbi \u0111ang mang thai v\u00e0 d\u1ef1 \u0111\u1ecbnh c\u00f3 thai.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ec7nh \u0111ang d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch cyclosporin A.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Ravenell-62,5<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c Ravenell-62,5, ng\u01b0\u1eddi b\u1ec7nh \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh l\u00e0m c\u00e1c x\u00e9t nghi\u1ec7m sau:<\/p>\n<ul>\n<li>X\u00e9t nghi\u1ec7m ch\u1ee9c n\u0103ng gan.<\/li>\n<li>X\u00e9t nghi\u1ec7m ki\u1ec3m tra xem c\u00f3 nguy c\u01a1 thi\u1ebfu m\u00e1u kh\u00f4ng.<\/li>\n<li>Th\u1eed thai \u0111\u1ed1i v\u1edbi n\u1eef gi\u1edbi.<\/li>\n<\/ul>\n<p>Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n l\u00e0m c\u00e1c x\u00e9t nghi\u1ec7m sau:<\/p>\n<ul>\n<li>X\u00e9t nghi\u1ec7m ch\u1ee9c n\u0103ng gan \u0111\u1ecbnh k\u1ef3 m\u1ed7i th\u00e1ng trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, n\u1ebfu t\u0103ng li\u1ec1u s\u1ebd x\u00e9t nghi\u1ec7m m\u00e1u sau 2 tu\u1ea7n.<\/li>\n<li>X\u00e9t nghi\u1ec7m n\u1ed3ng \u0111\u1ed9 hemoglobin \u0111\u1ecbnh k\u1ef3 m\u1ed7i th\u00e1ng trong 4 th\u00e1ng \u0111\u1ea7u, sau \u0111\u00f3 c\u1ee9 c\u00e1ch 3 th\u00e1ng t\u00e1i x\u00e9t nghi\u1ec7m l\u1ea1i.<\/li>\n<\/ul>\n<p>Tr\u01b0\u1eddng h\u1ee3p c\u00e1c x\u00e9t nghi\u1ec7m c\u00f3 b\u1ea5t th\u01b0\u1eddng, c\u00f3 th\u1ec3 l\u00e0m th\u00eam c\u00e1c x\u00e9t nghi\u1ec7m kh\u00e1c \u0111\u1ec3 t\u00ecm nguy\u00ean nh\u00e2n. Sau \u0111\u00f3 c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh ho\u1eb7c ng\u01b0ng d\u00f9ng thu\u1ed1c cho ph\u00f9 h\u1ee3p.<\/p>\n<p>Do th\u00e0nh ph\u1ea7n t\u00e1 d\u01b0\u1ee3c c\u00f3 th\u1ea7u d\u1ea7u n\u00ean Ravenell c\u00f3 th\u1ec3 g\u00e2y c\u00e1c r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Nghi\u00eam tr\u1ecdng nh\u1ea5t: g\u00e2y b\u1ea5t th\u01b0\u1eddng ch\u1ee9c n\u0103ng gan, thi\u1ebfu m\u00e1u.<\/p>\n<p>R\u1ea5t th\u01b0\u1eddng g\u1eb7p: \u0111au \u0111\u1ea7u, ph\u00f9.<\/p>\n<p>Th\u01b0\u1eddng g\u1eb7p: h\u1ed3i h\u1ed9p, \u0111\u1ecf b\u1eebng m\u1eb7t, qu\u00e1 m\u1eabn, tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n,&#8230;<\/p>\n<p>\u00cdt g\u1eb7p: gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u, v\u00e0ng da, v\u00e0ng m\u1eaft,..<\/p>\n<p>Hi\u1ebfm g\u1eb7p: ho\u1ea1i t\u1eed gan, suy gan, s\u1ed1c ph\u1ea3n v\u1ec7.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<table style=\"border-collapse: collapse; width: 100%; height: 211px;\">\n<tbody>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px; text-align: center;\">Thu\u1ed1c<\/td>\n<td style=\"width: 47.4394%; height: 21px; text-align: center;\">T\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px;\">Cyclosporin A<\/td>\n<td style=\"width: 47.4394%; height: 21px;\">T\u0103ng n\u1ed3ng \u0111\u1ed9 c\u1ee7a Bosentan<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px;\">C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf CYP2C9 v\u00e0 CYP3A4<\/td>\n<td style=\"width: 47.4394%; height: 21px;\">T\u0103ng n\u1ed3ng \u0111\u1ed9 c\u1ee7a Bosentan trong m\u00e1u<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px;\">Fluconazol, Ketoconazol, Itraconazol, Ritonavir, Voriconazol<\/td>\n<td style=\"width: 47.4394%; height: 21px;\">T\u0103ng n\u1ed3ng \u0111\u1ed9 c\u1ee7a Bosentan trong m\u00e1u<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px;\">Tacrolimus, Sirolimus<\/td>\n<td style=\"width: 47.4394%; height: 21px;\">T\u0103ng n\u1ed3ng \u0111\u1ed9 c\u1ee7a Ravenell-62,5 trong huy\u1ebft t\u01b0\u01a1ng<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px;\">Gibeclamid<\/td>\n<td style=\"width: 47.4394%; height: 21px;\">Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Gibeclamid<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"width: 52.5606%; height: 22px;\">Rifampicin<\/td>\n<td style=\"width: 47.4394%; height: 22px;\">Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Rifampicin<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px;\">Lopinavir + Ritonavir<\/td>\n<td style=\"width: 47.4394%; height: 21px;\">T\u0103ng \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 Bosentan trong m\u00e1u<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px;\">Thu\u1ed1c ch\u1ed1ng retrovirus<\/td>\n<td style=\"width: 47.4394%; height: 21px;\">Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 trong m\u00e1u v\u00e0 t\u00e1c d\u1ee5ng c\u1ee7a Nevirapine<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 52.5606%; height: 21px;\">Thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng<\/td>\n<td style=\"width: 47.4394%; height: 21px;\">L\u00e0m m\u1ea5t t\u00e1c d\u1ee5ng tr\u00e1nh thai<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 cho con b\u00fa v\u00ec c\u00f3 th\u1ec3 g\u00e2y nguy hi\u1ec3m cho thai nhi.<\/p>\n<h3>\u1ea2nh h\u01b0\u1edfng l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 kh\u1ea3 n\u0103ng \u1ea3nh h\u01b0\u1edfng c\u1ee7a thu\u1ed1c l\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, tuy nhi\u00ean Ravenell-62,5 c\u00f3 th\u1ec3 g\u00e2y h\u1ea1 huy\u1ebft \u00e1p n\u00ean c\u1ea7n th\u00f4ng b\u00e1o tr\u01b0\u1edbc v\u1edbi ng\u01b0\u1eddi b\u1ec7nh v\u1ec1 nguy c\u01a1 n\u00e0y.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>C\u00e1c bi\u1ec3u hi\u1ec7n qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 x\u1ea3y ra nh\u01b0 c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n: ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, n\u00f4n, bu\u1ed3n n\u00f4n,&#8230;<\/p>\n<p>C\u1ea7n th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u00e0 \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 x\u1eed tr\u00ed k\u1ecbp th\u1eddi.<\/p>\n<h3>Qu\u00ean li\u1ec1u<\/h3>\n<p>N\u1ebfu qu\u00ean 1 li\u1ec1u, h\u00e3y d\u00f9ng ngay khi nh\u1edb ra. N\u1ebfu g\u1ea7n v\u1edbi li\u1ec1u ti\u1ebfp theo c\u1ea7n b\u1ecf qua li\u1ec1u \u0111\u00f3, kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng li\u1ec1u g\u1ea5p \u0111\u00f4i.<\/p>\n<h3 id=\"bao-quan\" class=\"ftwp-heading\">B\u1ea3o qu\u1ea3n<\/h3>\n<p>\u0110\u1ec3 thu\u1ed1c tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em, \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp t\u1eeb m\u1eb7t tr\u1eddi.<\/p>\n<p>B\u1ea3o qu\u1ea3n Ravenell-62,5 \u1edf n\u01a1i c\u00f3 nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30 \u0111\u1ed9 v\u00e0 n\u01a1i tho\u00e1ng m\u00e1t.<\/p>\n<h2>Thu\u1ed1c Ravenell-62,5 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c Ravenell-62,5mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Ravenell-62,5 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng nh\u01b0:<\/p>\n<h2>T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Ravenell-62,5?<\/h2>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 60.6469%;\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 39.3531%;\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 60.6469%;\">D\u1ea1ng b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean n\u00e9n thu\u1eadn ti\u1ec7n cho vi\u1ec7c s\u1eed d\u1ee5ng v\u00e0 b\u1ea3o qu\u1ea3n.<\/p>\n<p>Thu\u1ed1c kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n n\u00ean c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng tr\u01b0\u1edbc ho\u1eb7c sau khi \u0103n.<\/p>\n<p>Ravenell-62,5 l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 trong t\u0103ng \u00e1p l\u1ef1c \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i, \u0111i\u1ec1u tr\u1ecb t\u0103ng \u00e1p l\u1ef1c ph\u1ed5i \u0111\u1ed9 III.<\/td>\n<td style=\"width: 39.3531%;\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf ngay li\u1ec1u \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Gi\u00e1 th\u00e0nh kh\u00e1 \u0111\u1eaft<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>Judy W M Cheng. (Th\u00e1ng 3-4 n\u0103m 2003).<em> Bosentan.<\/em> Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 9 n\u0103m 2023 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12713683\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/12713683\/<\/a>.<\/li>\n<li>C Weber, R Schmitt, H Birnboeck, G Hopfgartner, S P van Marle, P A Peeters, J H Jonkman, C R Jones. (Th\u00e1ng 8 n\u0103m 1996). <em>Pharmacokinetics and pharmacodynamics of the endothelin-receptor antagonist bosentan in healthy human subjects<\/em>. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 9 n\u0103m 2023 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8823230\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/8823230\/<\/a><\/li>\n<li>T\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Ravenell-62,5mg, xem th\u00eam <a href=\"https:\/\/vnras.com\/drug\/?attachment_id=45798\" rel=\"attachment wp-att-45798\">t\u1ea1i \u0111\u00e2y.<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Ravenell-62,5mg c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Bosentan gi\u00fap c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh t\u0103ng \u00e1p ph\u1ed5i v\u00e0 c\u00e1c b\u1ec7nh tim m\u1ea1ch c\u00f3 li\u00ean quan.<\/p>\n<p>C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng ch\u00ednh c\u1ee7a Bosentan l\u00e0 \u1ee9c ch\u1ebf c\u00e1c th\u1ee5 th\u1ec3 endothelin (ET) A v\u00e0 B.<\/p>\n<p>Vi\u1ec7c \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 ETA gi\u00fap gi\u1ea3m s\u1ef1 co b\u00f3p m\u1ea1ch m\u00e1u, gi\u1ea3m c\u0103ng th\u1eb3ng tr\u00ean th\u00e0nh m\u1ea1ch v\u00e0 gi\u1ea3m kh\u00e1ng c\u1ef1 m\u1ea1ch m\u00e1u. \u0110i\u1ec1u n\u00e0y l\u00e0m gi\u1ea3m \u00e1p l\u1ef1c trong m\u1ea1ch m\u00e1u v\u00e0 gi\u1ea3m kh\u1ea3 n\u0103ng t\u0103ng \u00e1p ph\u1ed5i.<\/p>\n<p>Ngo\u00e0i ra, Bosentan c\u0169ng \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 ETB, d\u1eabn \u0111\u1ebfn gi\u1ea3m s\u1ea3n xu\u1ea5t Endothelin v\u00e0 ng\u0103n ch\u1eb7n c\u00e1c t\u00e1c \u0111\u1ed9ng c\u1ee7a n\u00f3 l\u00ean m\u1ea1ch m\u00e1u.<\/p>\n","protected":false},"author":490,"featured_media":45807,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-45745","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/45745","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=45745"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/45807"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=45745"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=45745"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=45745"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}