{"id":41926,"date":"2023-09-13T11:54:54","date_gmt":"2023-09-13T04:54:54","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=41926"},"modified":"2025-07-24T14:03:49","modified_gmt":"2025-07-24T07:03:49","slug":"demoferidon-500-mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/demoferidon-500-mg\/","title":{"rendered":"Demoferidon 500mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/demoferidon-500-mg\/\">Demoferidon 500mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi DEMO S.A. PHARMACEUTICAL INDUSTRY- Hy L\u1ea1p, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-21008-18<\/strong><\/p>\n<h2>Demoferidon 500mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i l\u1ecd <strong>Demoferidon<\/strong> 500mg\u00a0 ch\u1ee9a:<br \/>\nHo\u1ea1t ch\u1ea5t: Deferoxamine mesilate\u2026500 mg.<br \/>\nT\u00e1 d\u01b0\u1ee3c: Kh\u00f4ng c\u00f3.<br \/>\nD\u1ea1ng b\u00e0o ch\u1ebf: Thu\u1ed1c b\u1ed9t pha dung d\u1ecbch ti\u00eam ho\u1eb7c ti\u00eam truy\u1ec1n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-21008-18.<br \/>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 l\u1ecd.<br \/>\nXu\u1ea5t x\u1ee9: Hy L\u1ea1p.<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Demoferidon 500mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Deferoxamine thu\u1ed9c nh\u00f3m chelat h\u00f3a. Deferoxamine c\u00f3 kh\u1ea3 n\u0103ng t\u1ea1o th\u00e0nh c\u00e1c ph\u1ee9c h\u1ee3p v\u1edbi c\u00e1c ion s\u1eaft h\u00f3a tr\u1ecb ba (ferrioxamin), nh\u00f4m h\u00f3a tr\u1ecb ba (aluminoxamin) b\u1ec1n v\u1eefng v\u00e0 kh\u00f4ng \u0111\u1ed9c. C\u00e1c ph\u1ee9c h\u1ee3p n\u00e0y kh\u00f4ng h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 t\u1ea5t c\u1ea3 c\u00e1c ph\u1ee9c h\u1ee3p \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh to\u00e0n th\u00e2n do s\u1eed d\u1ee5ng ngo\u00e0i \u0111\u01b0\u1eddng ti\u00eau h\u00f3a s\u1ebd nhanh ch\u00f3ng th\u1ea3i tr\u1eeb qua th\u1eadn m\u00e0 kh\u00f4ng g\u00e2y n\u00ean t\u00e1c h\u1ea1i n\u00e0o.<\/p>\n<p>Deferoxamine thu nh\u1eadn s\u1eaft t\u1ef1 do ho\u1eb7c k\u1ebft h\u1ee3p v\u1edbi ferritin v\u00e0 haemosiderin. T\u01b0\u01a1ng t\u1ef1, Deferoxamine t\u1ea1o ph\u1ee9c h\u1ee3p v\u1edbi nh\u00f4m li\u00ean k\u1ebft \u1edf m\u00f4. Deferoxamine l\u00e0m gi\u1ea3m \u1ee9 \u0111\u1ecdng s\u1eaft v\u00e0 nh\u00f4m \u1edf m\u00f4 v\u00e0 c\u00e1c c\u01a1 quan do th\u00fac \u0111\u1ea9y b\u00e0i ti\u1ebft hai ch\u1ea5t n\u00e0y qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 qua ph\u00e2n.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu<br \/>\nSau khi ti\u00eam b\u1eafp c\u1ea3 li\u1ec1u ho\u1eb7c truy\u1ec1n d\u01b0\u1edbi da ch\u1eadm, Deferoxamine \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh ch\u00f3ng. Khi ni\u00eam m\u1ea1c c\u00f2n nguy\u00ean v\u1eb9n th\u00ec l\u1ea1i k\u00e9m h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Trong th\u1ea9m ph\u00e2n m\u00e0ng b\u1ee5ng, Deferoxamine d\u00f9ng trong dung d\u1ecbch th\u1ea9m ph\u00e2n s\u1ebd \u0111\u01b0\u1ee3c h\u1ea5p thu.<\/p>\n<p>Ph\u00e2n b\u1ed1<br \/>\n\u1ede ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh, sau 30 ph\u00fat ti\u00eam b\u1eafp li\u1ec1u 10 mg\/kg n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a Deferoxamine \u0111\u1ea1t 15,5 pmol\/L (87 pg\/mL).<br \/>\nSau ti\u00eam 1 gi\u1edd, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t \u0111\u01b0\u1ee3c l\u00e0 3,7 micromol\/L , (2,3 pg\/mL).<br \/>\nCh\u1ec9 kho\u1ea3ng 10% Deferoxamine li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft thanh.<\/p>\n<p>Chuy\u1ec3n h\u00f3a<br \/>\n\u0110\u00e3 ph\u00e2n l\u1eadp \u0111\u01b0\u1ee3c 4 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a Deferoxamine t\u1eeb n\u01b0\u1edbc ti\u1ec3u.<\/p>\n<p>Th\u1ea3i tr\u1eeb<br \/>\nDeferoxamine v\u00e0 ferrioxamin c\u00f3 th\u1eddi gian b\u00e1n th\u1ea3i ph\u00e2n b\u1ed1 bi\u1ec3u ki\u1ebfn l\u1ea7n l\u01b0\u1ee3t l\u00e0 1 gi\u1edd; 2,4 gi\u1edd v\u00e0 th\u1eddi gian b\u00e1n th\u1ea3i cu\u1ed1i bi\u1ec3u ki\u1ebfn l\u00e0 6 gi\u1edd.<br \/>\nC\u00f3 22% li\u1ec1u d\u00f9ng xu\u1ea5t hi\u1ec7n trong n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng deferoxamine v\u00e0 1% d\u01b0\u1edbi d\u1ea1ng ferrioxamin trong v\u00f2ng 6 gi\u1edd sau khi ti\u00eam.<\/p>\n<h2>Thu\u1ed1c Demoferidon 500mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 31.2669%;\">Ch\u1ec9 \u0111\u1ecbnh<\/td>\n<td style=\"width: 68.7331%;\">Tr\u01b0\u1eddng h\u1ee3p c\u1ee5 th\u1ec3<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 31.2669%;\">\u0110i\u1ec1u tr\u1ecb th\u1eeba s\u1eaft m\u1ea1n t\u00ednh<\/td>\n<td style=\"width: 68.7331%;\">Nhi\u1ec5m haemosiderin do truy\u1ec1n m\u00e1u \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n th\u01b0\u1eddng xuy\u00ean nh\u1eadn truy\u1ec1n m\u00e1u (ch\u1ee7 y\u1ebfu \u1edf b\u1ec7nh nh\u00e2n thalassaemia).<br \/>\nNhi\u1ec5m s\u1eafc t\u1ed1 s\u1eaft nguy\u00ean ph\u00e1t v\u00e0 th\u1ee9 ph\u00e1t \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 c\u00e1c r\u1ed1i lo\u1ea1n \u0111\u1ed3ng th\u1eddi (nh\u01b0 thi\u1ebfu m\u00e1u n\u1eb7ng, gi\u1ea3m protein m\u00e1u, suy tim ho\u1eb7c suy th\u1eadn) ng\u0103n ng\u1eeba tr\u00edch m\u00e1u, t\u0129nh m\u1ea1ch.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 100%;\" colspan=\"2\">\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m \u0111\u1ed9c s\u1eaft c\u1ea5p t\u00ednh<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 31.2669%;\">\u0110i\u1ec1u tr\u1ecb th\u1eeba nh\u00f4m<\/td>\n<td style=\"width: 68.7331%;\">Th\u1ea9m ph\u00e2n duy tr\u00ec trong suy th\u1eadn giai \u0111o\u1ea1n cu\u1ed1i khi c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba (nh\u01b0 th\u1ea9m th\u1ea5u ng\u01b0\u1ee3c) th\u1ea5t b\u1ea1i.<br \/>\nB\u1ec7nh x\u01b0\u01a1ng li\u00ean quan \u0111\u1ebfn nh\u00f4m.<br \/>\nB\u1ec7nh n\u00e3o do th\u1ea9m ph\u00e2n.<br \/>\nThi\u1ebfu m\u00e1u li\u00ean quan \u0111\u1ebfn nh\u00f4m.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 100%;\" colspan=\"2\">Ch\u1ea9n \u0111o\u00e1n c\u00e1c b\u1ec7nh d\u1ef1 tr\u1eef s\u1eaft, th\u1eeba nh\u00f4m v\u00e0 c\u00e1c tr\u01b0\u1eddng h\u1ee3p thi\u1ebfu m\u00e1u.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Demoferidon 500mg<\/h2>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c d\u00f9ng qua \u0111\u01b0\u1eddng ti\u00eam b\u1eafp, t\u0129nh m\u1ea1ch ho\u1eb7c d\u01b0\u1edbi da. Kh\u00f4ng n\u00ean ti\u00eam v\u00e0o g\u1ea7n s\u00e1t ch\u00e2n bi khi d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam d\u01b0\u1edbi da.<\/p>\n<p>Th\u01b0\u1eddng d\u00f9ng d\u1ea1ng dung d\u1ecbch 10% b\u1eb1ng c\u00e1ch l\u1ea5y 500 mg b\u1ed9t thu\u1ed1c pha trong 5 ml n\u01b0\u1edbc pha ti\u00eam ( Natri clorid 0,9%, dung d\u1ecbch h\u1ed7n h\u1ee3p Natri clorid 0,9%, Dextrose 5% v\u00e0 Dextrose 5%, Ringer Lactat).<\/p>\n<p>\u1ede nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c li\u00ean t\u1ee5c ngo\u1ea1i tr\u00fa ho\u1eb7c th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c li\u00ean t\u1ee5c \u0111\u1ecbnh k\u1ef3 c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng Deferoxamine d\u1ea1ng h\u00f2a tan c\u00f3 th\u1ec3 th\u00eam v\u00e0o dung d\u1ecbch th\u1ea9m ph\u00e2n.<\/p>\n<h3>\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m \u0111\u1ed9c s\u1eaft c\u1ea5p t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em<\/h3>\n<p>C\u00e2n nh\u1eafc d\u00f9ng Deferoxamine ngo\u00e0i \u0111\u01b0\u1eddng ti\u00eau h\u00f3a trong nh\u1eefng t\u00ecnh hu\u1ed1ng sau:<br \/>\nB\u1ec7nh nh\u00e2n c\u00f3 nhi\u1ec1u h\u01a1n c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u1eb9 tho\u00e1ng qua (v\u00ed d\u1ee5 nhi\u1ec1u h\u01a1n m\u1ed9t giai \u0111o\u1ea1n n\u00f4n ho\u1eb7c \u0111i ngo\u00e0i ph\u00e2n m\u1ec1m).<br \/>\nB\u1ec7nh nh\u00e2n c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng ng\u1ee7 l\u1ecbm, \u0111au b\u1ee5ng nhi\u1ec1u, th\u1ec3 t\u00edch m\u00e1u gi\u1ea3m, ho\u1eb7c nhi\u1ec5m acid.<br \/>\nB\u1ec7nh nh\u00e2n khi ch\u1ee5p X-quang b\u1ee5ng d\u01b0\u01a1ng t\u00ednh c\u00f3 nhi\u1ec1u s\u1ef1 c\u1ea3n tia X.<br \/>\nB\u1ec7nh nh\u00e2n c\u00f3 tri\u1ec7u ch\u1ee9ng v\u1edbi n\u1ed3ng \u0111\u1ed9 s\u1eaft huy\u1ebft thanh cao h\u01a1n 300 \u2013 350 pg\/dL.<\/p>\n<p>Li\u1ec1u d\u00f9ng:<br \/>\nTruy\u1ec1n t\u0129nh m\u1ea1ch li\u00ean t\u1ee5c v\u1edbi t\u1ed1c \u0111\u1ed9 truy\u1ec1n khuy\u1ebfn c\u00e1o l\u00e0 15 mg\/kg\/gi\u1edd. Gi\u1ea3m t\u1ed1c \u0111\u1ed9 khi c\u00f3 th\u1ec3, sao cho t\u1ed5ng li\u1ec1u truy\u1ec1n kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 80mg\/kg.<\/p>\n<p>C\u00e1ch d\u00f9ng:<br \/>\nD\u00f9ng b\u01a1m truy\u1ec1n d\u1ec5 mang, truy\u1ec1n d\u01b0\u1edbi da ch\u1eadm trong th\u1eddi gian 8-12 gi\u1edd \u0111\u01b0\u1ee3c xem l\u00e0 hi\u1ec7u qu\u1ea3 v\u00e0 thu\u1eadn ti\u1ec7n cho nh\u1eefng b\u1ec7nh nh\u00e2n \u0111i l\u1ea1i \u0111\u01b0\u1ee3c, nh\u01b0ng c\u0169ng c\u00f3 th\u1ec3 truy\u1ec1n trong 24 gi\u1edd \u0111\u1ec3 t\u0103ng l\u01b0\u1ee3ng s\u1eaft b\u00e0i ti\u1ebft. T\u00f9y thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 th\u1eeba s\u1eaft b\u1ec7nh nh\u00e2n n\u00ean \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb 5-7 l\u1ea7n\/tu\u1ea7n.<br \/>\nTruy\u1ec1n d\u01b0\u1edbi da c\u00f3 hi\u1ec7u qu\u1ea3 h\u01a1n \u0111\u01b0\u1eddng ti\u00eam b\u1eafp. Ngo\u00e0i ra, c\u00f3 th\u1ec3 truy\u1ec1n t\u0129nh m\u1ea1ch trong khi truy\u1ec1n m\u00e1u, tuy nhi\u00ean l\u1ee3i \u00edch l\u00e2m s\u00e0ng c\u1ee7a \u0111\u01b0\u1eddng d\u00f9ng n\u00e0y v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1. Kh\u00f4ng n\u00ean cho dung d\u1ecbch Deferoxamine v\u00e0o t\u00fai \u0111\u1ef1ng m\u00e1u m\u00e0 c\u00f3 th\u1ec3 cho v\u00e0o d\u00e2y truy\u1ec1n m\u00e1u. C\u1ea7n nh\u1eafc nh\u1edf b\u1ec7nh nh\u00e2n v\u00e0 y t\u00e1 \u0111\u1ec3 tr\u00e1nh truy\u1ec1n nhanh.<br \/>\nTruy\u1ec1n t\u0129nh m\u1ea1ch li\u00ean t\u1ee5c \u0111\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng th\u1ec3 ti\u1ebfp t\u1ee5c truy\u1ec1n d\u01b0\u1edbi da v\u00e0 cho nh\u1eefng ng\u01b0\u1eddi c\u00f3 c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim ,th\u1ee9 ph\u00e1t do th\u1eeba s\u1eaft. Khi c\u1ea7n chel\u1ea1t h\u00f3a m\u1ea1nh n\u00ean \u0111o th\u01b0\u1eddng xuy\u00ean l\u01b0\u1ee3ng s\u1eaft b\u00e0i ti\u1ebft trong n\u01b0\u1edbc ti\u1ec3u trong 24 gi\u1edd (\u0111\u1ef1\u1eddng t\u0129nh m\u1ea1ch) v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u t\u01b0\u01a1ng \u1ee9ng.<br \/>\nR\u1eeda s\u1ea1ch d\u00e2y truy\u1ec1n, tr\u00e1nh truy\u1ec1n \u0111\u1ed9t ng\u1ed9t l\u01b0\u1ee3ng Deferoxamine c\u00f2n s\u00f3t l\u1ea1i trong kho\u1ea3ng kh\u00f4ng d\u00f9ng c\u1ee7a d\u00e2y truy\u1ec1n.<\/p>\n<h3>Ch\u1ea9n \u0111o\u00e1n b\u1ec7nh d\u1ef1 tr\u1eef s\u1eaft v\u00e0 c\u00e1c tr\u01b0\u1eddng h\u1ee3p thi\u1ebfu m\u00e1u<\/h3>\n<p>Ti\u00eam b\u1eafp Deferoxamine 500 mg. Trong 6 gi\u1edd sau, l\u1ea5y n\u01b0\u1edbc ti\u1ec3u v\u00e0 x\u00e1c \u0111\u1ecbnh h\u00e0m l\u01b0\u1ee3ng s\u1eaft. X\u00e1c \u0111\u1ecbnh th\u1eeba s\u1eaft khi l\u01b0\u1ee3ng s\u1eaft b\u00e0i ti\u1ebft t\u1eeb 1 -1,5 mg (18-27 micromol) trong th\u1eddi gian 6 gi\u1edd. N\u1ebfu gi\u00e1 tr\u1ecb n\u00e0y l\u1edbn h\u01a1n 1,5 mg (27 pmol) c\u00f3 th\u1ec3 xem nh\u01b0 b\u1ec7nh l\u00fd.<\/p>\n<h3>\u0110i\u1ec1u tr\u1ecb th\u1eeba nh\u00f4m \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn giai \u0111o\u1ea1n cu\u1ed1i<\/h3>\n<p>N\u00ean \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Deferoxamine 500 mg khi:<\/p>\n<ul>\n<li>C\u00f3 tri\u1ec7u ch\u1ee9ng suy c\u01a1 quan do th\u1eeba nh\u00f4m.<\/li>\n<li>N\u1ed3ng \u0111\u1ed9 nh\u00f4m trong huy\u1ebft thanh cao h\u01a1n 60 ng\/mL v\u00e0 th\u1eed nghi\u1ec7m deferoxamine d\u01b0\u01a1ng t\u00ednh.<\/li>\n<\/ul>\n<p>B\u1ec7nh nh\u00e2n \u0111ang th\u1ea9m ph\u00e2n duy tr\u00ec ho\u1eb7c l\u1ecdc m\u00e1u: 5 mg\/kg, d\u00f9ng m\u1ed9t l\u1ea7n\/ tu\u1ea7n.<br \/>\nB\u1ec7nh khi th\u1eed nghi\u1ec7m h\u1eadu deferoxamine n\u1ed3ng \u0111\u1ed9 nh\u00f4m huy\u1ebft thanh l\u00ean \u0111\u1ebfn 300 mcg\/mL: Truy\u1ec1n t\u0129nh m\u1ea1ch ch\u1eadm Deferoxamine trong 60 ph\u00fat cu\u1ed1i \u0111\u1ee3t th\u1ea9m ph\u00e2n.<br \/>\nB\u1ec7nh khi th\u1eed nghi\u1ec7m h\u1eadu Deferoxamine n\u1ed3ng \u0111\u1ed9 nh\u00f4m huy\u1ebft thanh cao h\u01a1n 300 mcg\/mL: Truy\u1ec1n t\u0129nh m\u1ea1ch ch\u1eadm Deferoxamine 5 gi\u1edd tr\u01b0\u1edbc \u0111\u1ee3t th\u1ea9m ph\u00e2n.<br \/>\nN\u00ean th\u1ef1c hi\u1ec7n th\u1eed nghi\u1ec7m truy\u1ec1n Deferoxamine 1 th\u00e1ng sau \u0111\u00f3 th\u1ef1c hi\u1ec7n th\u1eed nghi\u1ec7m th\u1ee9 hai sau b\u1ed1n tu\u1ea7n ho\u00e0n th\u00e0nh \u0111\u1ee3t \u0111i\u1ec1u tr\u1ecb Deferoxamine 3 th\u00e1ng. Kh\u00f4ng c\u1ea7n ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb Deferoxamine khi m\u00e0 n\u1ed3ng \u0111\u1ed9 nh\u00f4m huy\u1ebft thanh \u00edt h\u01a1n 50 ng\/mL so v\u1edbi gi\u00e1 tr\u1ecb c\u01a1 b\u1ea3n \u0111o \u0111\u01b0\u1ee3c trong hai l\u1ea7n th\u1eed nghi\u1ec7m truy\u1ec1n li\u00ean t\u1ee5c.<br \/>\nB\u1ec7nh nh\u00e2n \u0111ang th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c li\u00ean t\u1ee5c ngo\u1ea1i tr\u00fa ho\u1eb7c th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c li\u00ean t\u1ee5c \u0111\u1ecbnh k\u1ef3: D\u00f9ng Deferoxamine \u0111\u01b0\u1eddng trong m\u00e0ng b\u1ee5ng li\u1ec1u 5 mg\/kg, 1 l\u1ea7n\/ tu\u1ea7n tr\u01b0\u1edbc l\u1ea7n th\u1ea9m ph\u00e2n cu\u1ed1i c\u00f9ng c\u1ee7a ng\u00e0y \u0111\u00f3.<\/p>\n<p>C\u00f3 th\u1ec3 ng\u01b0ng s\u1eed d\u1ee5ng Deferoxamine khi t\u1ea5t c\u1ea3 nh\u1eefng ti\u00eau chu\u1ea9n sau \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 tri\u1ec7u ch\u1ee9ng c\u1ee7a nhi\u1ec5m \u0111\u1ed9c s\u1eaft to\u00e0n th\u00e2n.<\/li>\n<li>N\u1ed3ng \u0111\u1ed9 s\u1eaft huy\u1ebft thanh \u1edf m\u1ee9c b\u00ecnh th\u01b0\u1eddng ho\u1eb7c th\u1ea5p.<\/li>\n<li>Ch\u1ee5p X-quang b\u1ee5ng l\u1eb7p l\u1ea1i kh\u00f4ng c\u00f3 nhi\u1ec1u s\u1ef1 c\u1ea3n tia X.<\/li>\n<li>M\u00e0u n\u01b0\u1edbc ti\u1ec3u tr\u1edf v\u1ec1 b\u00ecnh th\u01b0\u1eddng n\u1ebfu b\u1ec7nh nh\u00e2n c\u00f3 n\u01b0\u1edbc ti\u1ec3u m\u00e0u h\u1ed3ng nh\u1ea1t khi kh\u1edfi \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi Deferoxamine.<\/li>\n<\/ul>\n<p>C\u00f3 th\u1ec3 c\u1ea7n ph\u1ea3i th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c ho\u1eb7c th\u1ea9m ph\u00e2n m\u00e1u \u0111\u1ec3 lo\u1ea1i b\u1ecf ferrioxamin n\u1ebfu xu\u1ea5t hi\u1ec7n thi\u1ec3u ni\u1ec7u ho\u1eb7c v\u00f4 ni\u1ec7u.<\/p>\n<h3>Th\u1eeba s\u1eaft m\u1ea1n t\u00ednh<\/h3>\n<p>Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em sau 10 \u2013 20 l\u1ea7n truy\u1ec1n m\u00e1u n\u00ean b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi Deferoxamine ho\u1eb7c khi n\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh \u0111\u1ea1t m\u1ee9c 1000 ng\/mL. T\u00f9y v\u00e0o t\u1eebng b\u1ec7nh nh\u00e2n v\u00e0 m\u1ee9c \u0111\u1ed9 th\u1eeba s\u1eaft m\u00e0 d\u00f9ng li\u1ec1u th\u00edch h\u1ee3p.<\/p>\n<p>Li\u1ec1u d\u00f9ng:<br \/>\nD\u00f9ng li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 hi\u1ec7u qu\u1ea3. Li\u1ec1u trung b\u00ecnh c\u00f3 th\u1ec3 t\u1eeb 20 \u2013 60 mg\/kg\/ng\u00e0y. N\u00ean d\u00f9ng li\u1ec1u kho\u1ea3ng 25 mg\/kg\/ng\u00e0y \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh &lt; 2000 ng\/mL, v\u00e0 d\u00f9ng li\u1ec1u 35 mg\/kg\/ng\u00e0y \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 ferritin t\u1eeb 2000 \u2013 3000 ng\/mL. Ch\u1ec9 s\u1eed d\u1ee5ng li\u1ec1u cao h\u01a1n khi l\u1ee3i \u00edch mang l\u1ea1i v\u01b0\u1ee3t tr\u1ed9i h\u01a1n so v\u1edbi nguy c\u01a1 b\u1ecb c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n.<br \/>\nC\u00f3 th\u1ec3 c\u1ea7n d\u00f9ng li\u1ec1u 55 mg\/kg\/ng\u00e0y \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh cao h\u01a1n. Ngo\u1ea1i tr\u1eeb khi c\u1ea7n chelat h\u00f3a r\u1ea5t m\u1ea1nh \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e3 t\u0103ng tr\u01b0\u1edfng ho\u00e0n to\u00e0n th\u00ec kh\u00f4ng n\u00ean th\u01b0\u1eddng xuy\u00ean d\u00f9ng li\u1ec1u v\u01b0\u1ee3t qu\u00e1 li\u1ec1u trung b\u00ecnh h\u00e0ng ng\u00e0y 50 mg\/kg\/ng\u00e0y. Nguy c\u01a1 nhi\u1ec5m \u0111\u1ed9c Deferoxamine t\u0103ng l\u00ean n\u1ebfu n\u1ed3ng \u0111\u1ed9 ferritin xu\u1ed1ng d\u01b0\u1edbi 1000 ng\/mL.<br \/>\n\u0110\u1ec3 \u0111\u00e1nh gi\u00e1 tr\u1ecb li\u1ec7u chelat ho\u00e1: \u0110\u1ea7u ti\u00ean n\u00ean theo d\u00f5i m\u1ed7i ng\u00e0y b\u00e0i ti\u1ebft s\u1eaft trong n\u01b0\u1edbc ti\u1ec3u 24 gi\u1edd. Kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u 500 mg\/ng\u00e0y, sau \u0111\u00f3 t\u0103ng li\u1ec1u cho \u0111\u1ebfn kh\u1ecb b\u00e0i ti\u1ebft s\u1eaft \u1ed5n \u0111\u1ecbnh. N\u00ean \u0111\u00e1nh gi\u00e1 t\u1ef7 l\u1ec7 b\u00e0i ti\u1ebft s\u1eaft trong n\u01b0\u1edbc ti\u1ec3u c\u00e1ch v\u00e0i tu\u1ea7n m\u1ed9t l\u1ea7n khi \u0111\u00e3 thi\u1ebft l\u1eadp \u0111\u01b0\u1ee3c li\u1ec1u th\u00edch h\u1ee3p.<\/p>\n<h3>Ch\u1ea9n \u0111o\u00e1n th\u1eeba nh\u00f4m \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n suy th\u1eadn giai \u0111o\u1ea1n cu\u1ed1i<\/h3>\n<p>\u1ede nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 nh\u00f4m huy\u1ebft thanh &gt; 60 ng\/mL c\u00f9ng v\u1edbi n\u1ed3ng \u0111\u1ed9 ferritin huy\u1ebft thanh &gt;100ng\/mL khuy\u1ebfn c\u00e1o truy\u1ec1n Deferoxamine.<br \/>\nL\u1ea5y m\u1eabu m\u00e1u \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh n\u1ed3ng \u0111\u1ed9 nh\u00f4m c\u01a1 b\u1ea3n trong huy\u1ebft thanh ngay tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111\u1ee3t th\u1ea9m ph\u00e2n m\u00e1u,.<br \/>\nD\u00f9ng li\u1ec1u 5 mg\/kg truy\u1ec1n t\u0129nh m\u1ea1ch ch\u1eadm trong th\u1eddi gian 60 ph\u00fat cu\u1ed1i c\u1ee7a \u0111\u1ee3t th\u1ea5m ph\u00e2n m\u00e1u.<\/p>\n<h3>S\u1eed d\u1ee5ng \u1edf ng\u01b0\u1eddi gi\u00e0<\/h3>\n<p>C\u1ea9n th\u1eadn khi ch\u1ecdn li\u1ec1u cho ng\u01b0\u1eddi gi\u00e0. Th\u00f4ng th\u01b0\u1eddng kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u th\u1ea5p trong kho\u1ea3ng li\u1ec1u. Xem x\u00e9t suy gi\u1ea3m ch\u1ee9c n\u0103ng gan, th\u1eadn ho\u1eb7c tim, v\u00e0 c\u1ee7a c\u00e1c b\u1ec7nh khi k\u00e8m ho\u1eb7c \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Demoferidon 500mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c \u1edf b\u1ec7nh nh\u00e2n qu\u00e1 m\u1eabn v\u1edbi Deferoxamine mesilate.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Demoferidon 500mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>\u1ede b\u1ec7nh nh\u00e2n suy th\u1eadn do ph\u1ee9c h\u1ee3p kim lo\u1ea1i \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua th\u1eadn th\u1ea9m ph\u00e2n m\u00e1u s\u1ebd l\u00e0m t\u0103ng th\u1ea3i tr\u1eeb nh\u00f4m ho\u1eb7c s\u1eaft \u0111\u01b0\u1ee3c chelat h\u00f3a v\u00ec v\u1eady c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng thu\u1ed1c \u1edf b\u1ec7nh nh\u00e2n n\u00e0y.<\/p>\n<p>\u1ede nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh n\u00e3o li\u00ean quan \u0111\u1ebfn nh\u00f4m d\u00f9ng Deferoxamine \u0111\u01a1n \u0111\u1ed9c c\u00f3 th\u1ec3 l\u00e0m n\u1eb7ng th\u00eam t\u00ecnh tr\u1ea1ng suy ch\u1ee9c n\u0103ng th\u1ea7n kinh.<\/p>\n<p>Ch\u1ec9 n\u00ean d\u00f9ng Deferoxamine d\u1ea1ng truy\u1ec1n t\u0129nh m\u1ea1ch ch\u1eadm \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 tr\u00e1nh g\u00e2y h\u1ea1 huy\u1ebft \u00e1p v\u00e0 s\u1ed1c.<\/p>\n<p>Kh\u00f4ng n\u00ean d\u00f9ng \u0111\u01b0\u1eddng d\u01b0\u1edbi da khi n\u1ed3ng \u0111\u1ed9 v\u00e0 (ho\u1eb7c) li\u1ec1u cao h\u01a1n khuy\u1ebfn c\u00e1o. Nh\u1eefng b\u1ec7nh nh\u00e2n th\u1eeba s\u1eaft s\u1ebd r\u1ea5t nh\u1ea1y c\u1ea3m v\u1edbi ti\u00eam. N\u00eau b\u1ec7nh nh\u00e2n c\u00f3 nh\u1eefng d\u1ea5u hi\u1ec7u nhi\u1ec5m khu\u1ea9n th\u00ec n\u00ean ng\u01b0ng d\u00f9ng Deferoxamine v\u00e0 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng kh\u00e1ng sinh th\u00edch h\u1ee3p. C\u00f3 th\u1ec3 b\u1eaft \u0111\u1ea7u l\u1ea1i khi \u0111\u00e3 h\u1ebft nhi\u1ec5m khu\u1ea9n.<\/p>\n<p>R\u1ea5t hi\u1ebfm tr\u01b0\u1eddng h\u1ee3p b\u00e1o c\u00e1o b\u1ecb nhi\u1ec5m n\u1ea5m mucor (nhi\u1ec5m n\u1ea5m n\u1eb7ng) \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng Deferoxamine \u0111i\u1ec1u tr\u1ecb th\u1eeba s\u1eaft ho\u1eb7c th\u1eeba nh\u00f4m, m\u1ed9t v\u00e0i tr\u01b0\u1eddng h\u1ee3p t\u1eed vong. Ng\u01b0ng d\u00f9ng Deferoxamine n\u1ebfu c\u00f3 b\u1ea5t k\u1ef3 tri\u1ec7u ch\u1ee9ng ho\u1eb7c d\u1ea5u hi\u1ec7u \u0111\u1eb7c tr\u01b0ng n\u00e0o x\u1ea3y ra,\u00a0 x\u00e9t nghi\u1ec7m v\u1ec1 n\u1ea5m v\u00e0 ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb th\u00edch h\u1ee3p ngay.<\/p>\n<p>Trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb Deferoxamine l\u00e2u d\u00e0i \u0111\u00e3 x\u1ea3y ra r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c v\u00e0 th\u00ednh gi\u00e1c. Do \u0111\u00f3,\u00a0 tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb Deferoxamine d\u00e0i h\u1ea1n ho\u1eb7c m\u1ed7i 3 th\u00e1ng trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb n\u00ean th\u1ef1c hi\u1ec7n c\u00e1c th\u1eed nghi\u1ec7m v\u1ec1 th\u1ecb gi\u00e1c v\u00e0 th\u00ednh gi\u00e1c. Ng\u1eebng \u0111i\u1ec1u tr\u1ecb n\u1ebfu r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c ho\u1eb7c th\u00ednh gi\u00e1c x\u1ea3y ra. C\u00e1c r\u1ed1i lo\u1ea1n n\u00e0y th\u01b0\u1eddng c\u00f3 th\u1ec3 h\u1ed3i ph\u1ee5c \u0111\u01b0\u1ee3c. N\u1ebfu \u0111i\u1ec1u tr\u1ecb l\u1ea1i th\u00ec d\u00f9ng Deferoxamine \u1edf li\u1ec1u th\u1ea5p h\u01a1n, n\u00ean theo d\u00f5i k\u1ef9 ch\u1ee9c n\u0103ng th\u1ecb gi\u00e1c\/ th\u00ednh gi\u00e1c x\u00e9t gi\u1eefa l\u1ee3i \u00edch v\u00e0 nguy c\u01a1.<\/p>\n<p>C\u00f3 li\u00ean quan \u0111\u1ebfn ch\u1eadm t\u0103ng tr\u01b0\u1edfng khi s\u1eed d\u1ee5ng li\u1ec1u cao Deferoxamine kh\u00f4ng h\u1ee3p l\u00fd \u1edf nh\u1eefng b\u1ec7nh nh\u1eadn c\u00f3 n\u1ed3ng \u0111\u1ed9 ferritin th\u1ea5p ho\u1eb7c \u1edf tr\u1ebb em (nh\u1ecf h\u01a1n 3 tu\u1ed5i). \u1ede m\u1ed9t v\u00e0i tr\u01b0\u1eddng h\u1ee3p gi\u1ea3m li\u1ec1u d\u00f9ng c\u00f3 th\u1ec3 ph\u1ee5c h\u1ed3i t\u1ef7 l\u1ec7 t\u0103ng tr\u01b0\u1edfng \u0111\u1ebfn m\u1ee9c tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb. N\u00ean ki\u1ec3m tra c\u00e2n n\u1eb7ng v\u00e0 chi\u1ec1u cao m\u1ed7i 3 th\u00e1ng \u1edf tr\u1ebb em.<br \/>\nN\u1ebfu li\u1ec1u d\u00f9ng th\u1ea5p h\u01a1n 40 mg\/kg th\u00ec ch\u1eadm t\u1eb7ng tr\u01b0\u1eddng do Deferoxamine hi\u1ebfm khi x\u1ea3y ra. N\u1ebfu ch\u1eadm t\u0103ng tr\u01b0\u1edfng x\u1ea3y ra do d\u00f9ng cao h\u01a1n li\u1ec1u tr\u00ean th\u00ec sau \u0111\u00f3 gi\u1ea3m li\u1ec1u c\u00f3 th\u1ec3 \u0111\u1ec3 tr\u1edf v\u1ec1 t\u1ed1c \u0111\u1ed9 t\u0103ng tr\u01b0\u1edfng b\u00ecnh th\u01b0\u1eddng, tuy nhi\u00ean s\u1ebd kh\u00f4ng \u0111\u1ea1t \u0111\u01b0\u1ee3c chi\u1ec1u cao mong mu\u1ed1n.<\/p>\n<p>Sau khi \u0111i\u1ec1u tr\u1ecb li\u1ec1u cao Deferoxamine truy\u1ec1n t\u0129nh m\u1ea1ch \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m \u0111\u1ed9c s\u1eaft c\u1ea5p c\u00f3 th\u1ec3 x\u1ea3y ra h\u1ed9i ch\u1ee9ng suy h\u00f4 h\u1ea5p c\u1ea5p v\u00e0 hi\u1ec7n t\u01b0\u1ee3ng n\u00e0y c\u0169ng x\u1ea3y ra \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb Th\u1ea1lassaemia. Do \u0111\u00f3 kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng li\u1ec1u cao h\u01a1n li\u1ec1u khuy\u1ebfn c\u00e1o h\u00e0ng ng\u00e0y.<\/p>\n<p>C\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u erythropoietin n\u1ebfu d\u00f9ng chung v\u1edbi Deferoxamine v\u00ec s\u1ebd \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 nh\u00f4m.<br \/>\nKhi \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi Deferoxamine v\u00e0 li\u1ec1u cao vitamin C (nhi\u1ec1u h\u01a1n 500 mg\/ng\u00e0y \u1edf ng\u01b0\u1eddi l\u1edbn th\u1eeba s\u1eaft m\u1ea1n t\u00ednh n\u1eb7ng) c\u00f3 th\u1ec3 x\u1ea3y ra suy ch\u1ee9c n\u0103ng tim. Ng\u1eebng d\u00f9ng vitamin C th\u00ec r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng tim \u0111\u01b0\u1ee3c ph\u1ee5c h\u1ed3i. Khi d\u00f9ng \u0111\u1ed3ng th\u1eddi vitamin C v\u00e0 Deferoxamine n\u00ean ch\u00fa \u00fd:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n b\u1ecb suy tim kh\u00f4ng n\u00ean b\u1ed5 sung vitamin C.<\/li>\n<li>Sau khi kh\u1edfi \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb \u0111\u1ec1u \u0111\u1eb7n v\u1edbi Deferoxamine 1 th\u00e1ng th\u00ec m\u1edbi b\u1eaft \u0111\u1ea7u b\u1ed5 sung vitamin C.<\/li>\n<li>B\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng \u0111\u1ec1u \u0111\u1eb7n Deferoxamine c\u00f3 th\u1ec3 d\u00f9ng vitamin C, t\u1ed1t nh\u1ea5t l\u00e0 d\u00f9ng ngay sau khi c\u1ed1 \u0111\u1ecbnh xong b\u01a1m truy\u1ec1n.<\/li>\n<li>Ng\u01b0\u1eddi l\u1edbn kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng v\u01b0\u1ee3t qu\u00e1 li\u1ec1u h\u1eb1ng ng\u00e0y 200mg vitamin C v\u00e0 chia l\u00e0m nhi\u1ec1u l\u1ea7n.<\/li>\n<\/ul>\n<p>Theo d\u00f5i ch\u1ee9c n\u0103ng tim trong su\u1ed1t th\u1eddi gian \u0111i\u1ec1u tr\u1ecb ph\u1ed1i h\u1ee3p tr\u00ean.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<table style=\"border-collapse: collapse; width: 100%; height: 210px;\">\n<tbody>\n<tr style=\"height: 21px;\">\n<td style=\"width: 13.6119%; height: 21px; text-align: center;\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/td>\n<td style=\"width: 86.3881%; height: 21px; text-align: center;\">Bi\u1ec3u hi\u1ec7n<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 13.6119%; height: 21px;\" rowspan=\"2\">Th\u01b0\u1eddng g\u1eb7p<\/td>\n<td style=\"width: 86.3881%; height: 21px;\">\u0110au kh\u1edbp\/ \u0111au c\u01a1, nh\u1ee9c \u0111\u1ea7u, m\u1ec1 \u0111ay, bu\u1ed3n n\u00f4n, s\u1ed1t.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 86.3881%; height: 21px;\">R\u1ed1i lo\u1ea1n c\u01a1 x\u01b0\u01a1ng v\u00e0 m\u00f4 li\u00ean k\u1ebft: ch\u1eadm t\u0103ng tr\u01b0\u1edfng v\u00e0 r\u1ed1i lo\u1ea1n x\u01b0\u01a1ng. N\u1ebfu d\u00f9ng li\u1ec1u 40mg\/kg tr\u1edf xu\u1ed1ng th\u00ec s\u1ebd gi\u1ea3m thi\u1ec3u nguy c\u01a1 n\u00e0y.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 13.6119%; height: 21px;\">\u00cdt g\u1eb7p<\/td>\n<td style=\"width: 86.3881%; height: 21px;\">N\u00f4n, \u0111au b\u1ee5ng, suy\u1ec5n.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 13.6119%; height: 21px;\" rowspan=\"4\">Hi\u1ebfm g\u1eb7p<\/td>\n<td style=\"width: 86.3881%; height: 21px;\">R\u1ed1i lo\u1ea1n tai v\u00e0 m\u00ea \u0111\u1ea1o: \u00f9 tai, \u0111i\u1ebfc th\u1ea7n kinh c\u1ea3m gi\u00e1c.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 86.3881%; height: 21px;\">R\u1ed1i lo\u1ea1n m\u1eaft: m\u1ea5t th\u1ecb gi\u00e1c, \u00e1m \u0111i\u1ec3m, nh\u00ecn m\u1edd, tho\u00e1i h\u00f3a v\u00f5ng m\u1ea1c, vi\u00eam th\u1ea7n kinh th\u1ecb gi\u00e1c, t\u1ed5n h\u1ea1i th\u1ecb tr\u01b0\u1eddng, \u0111\u1ee5c th\u1ee7y tinh th\u1ec3, qu\u00e1ng g\u00e0, lo\u1ea1n s\u1eafc th\u1ecb, \u0111\u1ee5c gi\u00e1c m\u1ea1c.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 86.3881%; height: 21px;\">R\u1ed1i lo\u1ea1n th\u1eadn v\u00e0 h\u1ec7 ti\u1ebft ni\u1ec7u: suy th\u1eadn.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 86.3881%; height: 21px;\">R\u1ed1i lo\u1ea1n m\u1ea1ch: n\u1ebfu kh\u00f4ng tu\u00e2n th\u1ee7 th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f3 th\u1ec3 h\u1ea1 huy\u1ebft \u00e1p, s\u1ed1c, nh\u1ecbp tim nhanh.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 13.6119%; height: 21px;\" rowspan=\"7\">R\u1ea5t hi\u1ebfm g\u1eb7p<\/td>\n<td style=\"width: 86.3881%; height: 21px;\">R\u1ed1i lo\u1ea1n h\u1ec7 mi\u1ec5n d\u1ecbch: ph\u00f9 m\u1ea1ch th\u1ea7n kinh, ph\u1ea3n v\u1ec7.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 86.3881%; height: 21px;\">R\u1ed1i lo\u1ea1n da v\u00e0 m\u00f4 d\u01b0\u1edbi da: ph\u00e1t ban to\u00e0n th\u00e2n.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 86.3881%;\">R\u1ed1i lo\u1ea1n h\u00f4 h\u1ea5p, ng\u1ef1c v\u00e0 trung th\u1ea5t: th\u00e2m nhi\u1ec5m ph\u1ed5i suy h\u00f4 h\u1ea5p c\u1ea5p.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 86.3881%;\">R\u1ed1i lo\u1ea1n h\u1ec7 th\u1ea7n kinh: ch\u00f3ng m\u1eb7t, th\u00fac \u0111\u1ea9y ho\u1eb7c l\u00e0m n\u1eb7ng th\u00eam b\u1ec7nh n\u00e3o do th\u1ea9m ph\u00e2n li\u00ean quan \u0111\u1ebfn nh\u00f4m, d\u1ecb c\u1ea3m, b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 86.3881%;\">R\u1ed1i lo\u1ea1n h\u1ec7 ti\u00eau h\u00f3a: ti\u00eau ch\u1ea3y.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 86.3881%;\">R\u1ed1i lo\u1ea1n h\u1ec7 b\u1ea1ch huy\u1ebft v\u00e0 m\u00e1u: r\u1ed1i lo\u1ea1n m\u00e1u.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 86.3881%;\">Nhi\u1ec5m khu\u1ea9n v\u00e0 nhi\u1ec5m k\u00fd sinh tr\u00f9ng: vi\u00eam d\u1ea1 d\u00e0y ru\u1ed9t yersinia.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u1ede nh\u1eefng b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb th\u1eeba nh\u00f4m d\u00f9ng Deferoxamine c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m canxi huy\u1ebft thanh v\u00e0 l\u00e0m n\u1eb7ng th\u00eam t\u0103ng n\u0103ng tuy\u1ebfn c\u1eadn gi\u00e1p.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>D\u00f9ng Deferoxamine m\u00e0 u\u1ed1ng nhi\u1ec1u l\u1ea7n li\u1ec1u cao vitamin C ( t\u1ed1i \u0111a 200 mg\/ng\u00e0y) c\u00f3 th\u1ec3 l\u00e0m t\u0103ng b\u00e0i ti\u1ebft ph\u1ee9c h\u1ee3p s\u1eaft. V\u00ec v\u1eady c\u1ea7n ch\u00fa \u00fd:<\/p>\n<ul>\n<li>Theo d\u00f5i ch\u1ee9c n\u0103ng tim trong su\u1ed1t th\u1eddi gian \u0111i\u1ec1u tr\u1ecb k\u1ebft h\u1ee3p.<\/li>\n<li>Kh\u00f4ng n\u00ean d\u00f9ng vitamin C trong th\u00e1ng \u0111\u1ea7u ti\u00ean \u0111i\u1ec1u tr\u1ecb v\u1edbi Deferoxamine v\u00e0 chi \u0111\u01b0\u1ee3c d\u00f9ng n\u1ebfu b\u1ec7nh nh\u00e2n \u0111ang \u0111i\u1ec1u tr\u1ecb v\u1edbi Deferoxamine \u0111\u1ec1u \u0111\u1eb7n.<\/li>\n<\/ul>\n<p>\u0110i\u1ec1u tr\u1ecb ph\u1ed1i h\u1ee3p Deferoxamine v\u00e0 vitamin C li\u1ec1u cao ( h\u01a1n 500 mg\/ ng\u00e0y) \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ec7nh d\u1ef1 tr\u1eef s\u1eaft m\u1ea1n t\u00ednh n\u1eb7ng c\u00f3 th\u1ec3 l\u00e0m suy gi\u1ea3m ch\u1ee9c n\u0103ng tim. Do \u0111\u00f3, kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng vitamin C cho b\u1ec7nh nh\u00e2n suy tim.<br \/>\n\u0110\u1ec3 tr\u00e1nh t\u00ecnh tr\u1ea1ng h\u00f4n m\u00ea k\u00e9o d\u00e0i, kh\u00f4ng ph\u1ed1i h\u1ee3p Deferoxamine v\u1edbi proclorperazin.<br \/>\nDo s\u1ef1 \u0111\u00e0o th\u1ea3i nhanh ph\u1ee9c h\u1ee3p Deferoxamine g\u1eafn v\u1edbi Galli ra n\u01b0\u1edbc ti\u1ec3u n\u00ean k\u1ebft qu\u1ea3 h\u00ecnh \u1ea3nh Galli c\u00f3 th\u1ec3 b\u1ecb sai l\u1ec7ch. V\u00ec v\u1eady, kh\u00f4ng n\u00ean d\u00f9ng Deferoxamine 48 gi\u1edd tr\u01b0\u1edbc khi ch\u1ee5p nh\u1ea5p nh\u00e1y.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai<br \/>\n\u1ede \u0111\u1ed9ng v\u1eadt d\u00f9ng Deferoxamine \u0111\u00e3 c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng g\u00e2y qu\u00e1i thai.<br \/>\nPh\u1ee5 n\u1eef cho con b\u00fa<br \/>\nCh\u01b0a x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c Deferoxamine mesilate c\u00f3 \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng.<br \/>\nV\u00ec v\u1eady kh\u00f4ng n\u00ean d\u00f9ng deferoxamine mesilate cho hai \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y \u0111\u1eb7c bi\u1ec7t trong 3 th\u00e1ng \u0111\u1ea7u thai k\u00ec, tr\u1eeb tr\u01b0\u1eddng h\u1ee3p c\u00e2n nh\u1eafc l\u1ee3i \u00edch cao h\u01a1n nguy c\u01a1.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Nhi\u1ec5m \u0111\u1ed9c c\u1ea5p r\u1ea5t kh\u00f3 x\u1ea3y ra v\u00ec Deferoxamine th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u00f9ng ngo\u00e0i \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Sau khi \u0111i\u1ec1u tr\u1ecb li\u1ec1u cao Deferoxamine \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch \u1edf b\u1ec7nh nh\u00e2n nhi\u1ec5m \u0111\u1ed9c s\u1eaft c\u1ea5p v\u00e0 b\u1ec7nh nh\u00e2n thalassemia \u0111\u00e3 x\u1ea3y ra h\u1ed9i ch\u1ee9ng suy h\u00f4 h\u1ea5p c\u1ea5p.<\/p>\n<p>C\u00e1c bi\u1ec3u hi\u1ec7n c\u1ee7a qu\u00e1 li\u1ec1u bao g\u1ed3m:<br \/>\nH\u1ea1 huy\u1ebft \u00e1p, nh\u1ecbp tim nhanh. \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n d\u00f9ng qu\u00e1 li\u1ec1u Deferoxamine tri\u1ec7u ch\u1ee9ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a th\u01b0\u1eddng x\u1ea3y ra. D\u00f9ng qu\u00e1 li\u1ec1u Deferoxamine \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch c\u00f3 th\u1ec3 t\u1ea1m th\u1eddi g\u00e2y ra m\u1ea5t th\u1ecb gi\u00e1c c\u1ea5p t\u00ednh, nh\u1ee9c \u0111\u1ea7u, bu\u1ed3n n\u00f4n, m\u1ea5t ng\u00f4n ng\u1eef, k\u00edch \u0111\u1ed9ng, nh\u1ecbp tim ch\u1eadm, h\u1ea1 huy\u1ebft \u00e1p v\u00e0 suy th\u1eadn c\u1ea5p.<\/p>\n<p>C\u00e1ch \u0111i\u1ec1u tr\u1ecb<br \/>\nKh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho Deferoxamine nh\u01b0ng khi gi\u1ea3m li\u1ec1u Deferoxamine c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng c\u00f3 th\u1ec3 gi\u1ea3m b\u1edbt. \u00c1p d\u1ee5ng th\u00eam c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 th\u00edch h\u1ee3p.<\/p>\n<h2>Thu\u1ed1c Demoferidon 500mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c Demoferidon 500mg<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<br \/>\nThu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/paolucci-500mg\/\">Paolucci 500mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa ch\u1ee9a Deferiprone 500mg c\u00f3 d\u1ea1ng b\u00e0o ch\u1ebf l\u00e0 vi\u00ean nang c\u1ee9ng. Thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb th\u1eeba s\u1eaft, ch\u1ee7 y\u1ebfu \u1edf ng\u01b0\u1eddi b\u1ec7nh b\u1ecb Thalassemia m\u00e0 li\u1ec7u ph\u00e1p deferoxamin kh\u00f4ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ho\u1eb7c kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u1ee7. Thu\u1ed1c c\u00f3 gi\u00e1 kho\u1ea3ng 240.000 \u0111\u1ed3ng\/ 1 h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean nang.<\/p>\n<h2>T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c?<\/h2>\n<table style=\"border-collapse: collapse; width: 100%; height: 149px;\">\n<tbody>\n<tr style=\"height: 21px;\">\n<td style=\"width: 50%; height: 21px; text-align: center;\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 50%; height: 21px; text-align: center;\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr style=\"height: 86px;\">\n<td style=\"width: 50%; height: 86px;\">Deferoxamine \u0111\u00e3 \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng qu\u00e1 t\u1ea3i s\u1eaft, c\u1ea5p t\u00ednh ho\u1eb7c m\u00e3n t\u00ednh.<\/td>\n<td style=\"width: 50%; height: 86px;\">Deferoxamine ph\u1ea3i \u0111i\u1ec1u tr\u1ecb d\u00e0i h\u1ea1n v\u00e0 li\u1ec1u cao v\u00ec v\u1eady nguy c\u01a1 x\u1ea3y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 l\u00e0 r\u1ea5t cao: h\u1ea1 huy\u1ebft \u00e1p, suy th\u1eadn, nhi\u1ec5m \u0111\u1ed9c th\u1ea7n kinh, ch\u1eadm ph\u00e1t tri\u1ec3n v\u00e0 nhi\u1ec5m tr\u00f9ng c\u01a1 h\u1ed9i.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 50%; height: 21px;\">Deferoxamine t\u1ea1o ph\u1ee9c h\u1ee3p v\u1edbi s\u1eaft v\u00e0 nh\u00f4m. Ph\u1ee9c h\u1ee3p n\u00e0y kh\u00f4ng h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 s\u1ebd nhanh ch\u00f3ng th\u1ea3i tr\u1eeb qua th\u1eadn m\u00e0 kh\u00f4ng g\u00e2y n\u00ean t\u00e1c h\u1ea1i n\u00e0o.<\/td>\n<td style=\"width: 50%; height: 21px;\">Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng ti\u00eam v\u00e0 li\u1ec1u d\u00f9ng kh\u00e1 ph\u1ee9c t\u1ea1p. V\u00ec v\u1eady, c\u1ea7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n v\u00e0 gi\u00e1m s\u00e1t b\u1edfi nh\u00e2n vi\u00ean y t\u1ebf.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 50%; height: 21px;\">Nghi\u00ean c\u1ee9u m\u1edbi g\u1ea7n \u0111\u00e2y tr\u00ean chu\u1ed9t \u0111\u00e3 ch\u1ee9ng minh m\u1ed9t t\u00e1c d\u1ee5ng m\u1edbi c\u1ee7a Deferoxamine l\u00e0 c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m t\u00ecnh tr\u1ea1ng vi\u00eam v\u00e0 t\u1ea1o x\u01b0\u01a1ng trong m\u00f4 h\u00ecnh tr\u1ed3ng l\u1ea1i r\u0103ng. T\u1ea1o ti\u1ec1n \u0111\u1ec1 \u0111\u1ec3 nghi\u00ean c\u1ee9u s\u00e2u h\u01a1n v\u1ec1 c\u00e1c t\u00e1c d\u1ee5ng kh\u00e1c c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y.<\/td>\n<td style=\"width: 50%; height: 21px;\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u00e1c gi\u1ea3 James Velasquez; Anton A. Wray. (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 22 th\u00e1ng 05 n\u0103m 2023). <em>Deferoxamine &#8211; StatPearls<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 13 th\u00e1ng 09 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557654\/\" rel=\"noopener\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557654\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3\u00a0 Y Bentur , M McGuigan , G Koren (Th\u1eddi gian ph\u00e1t h\u00e0nh n\u0103m 1991). <em>Deferoxamine (desferrioxamine)<\/em>. <em>New toxicities for an old drug<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 13 th\u00e1ng 09 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2029352\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/2029352\/<\/a><\/li>\n<li>T\u00e1c gi\u1ea3\u00a0 Ko Eun Lee (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 30 th\u00e1ng 7 n\u0103m 2021). <em>Deferoxamine Reduces Inflammation and Osteoclastogenesis in Avulsed Teeth<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 13 th\u00e1ng 09 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34360988\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34360988\/<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Demoferidon 500mg d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb th\u1eeba s\u1eaft m\u1ea1n t\u00ednh, nhi\u1ec5m \u0111\u1ed9c s\u1eaft c\u1ea5p t\u00ednh, th\u1eeba nh\u00f4m<\/p>\n","protected":false},"author":1,"featured_media":41927,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-41926","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/41926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=41926"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/41927"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=41926"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=41926"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=41926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}