{"id":35621,"date":"2023-07-07T12:08:57","date_gmt":"2023-07-07T05:08:57","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=35621"},"modified":"2026-01-31T09:39:31","modified_gmt":"2026-01-31T02:39:31","slug":"garnotal-100mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/garnotal-100mg\/","title":{"rendered":"Garnotal 100mg"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Garnotal 100mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c Danapha, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-24084-16.<\/strong><\/p>\n

Thu\u1ed1c Garnotal 100mg l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n
Th\u00e0nh ph\u1ea7n<\/h3>\n
Thu\u1ed1c Garnotal 100mg<\/strong> l\u00e0 thu\u1ed1c ch\u1ed1ng co gi\u1eadt v\u1edbi th\u00e0nh ph\u1ea7n ch\u1ee9a:<\/span><\/p>\n
Phenobarbital 100mg \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n.<\/span><\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: VD-24084-16.<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.<\/span><\/p>\n
Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam.<\/p>\n
B\u1ea3o qu\u1ea3n<\/h3>\n
B\u1ea3o qu\u1ea3n thu\u1ed1c Garnotal 100mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, tr\u00e1nh \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp, nhi\u1ec7t \u0111\u1ed9 b\u1ea3o qu\u1ea3n d\u01b0\u1edbi 30 \u0111\u1ed9 C. \u0110\u1ec3 xa t\u1ea7m v\u1edbi v\u00e0 t\u1ea7m nh\u00ecn c\u1ee7a tr\u1ebb nh\u1ecf.<\/span><\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Garnotal 100mg<\/span><\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n
Thu\u1ed1c Garnotal 100mg t\u00e1c d\u1ee5ng<\/strong> ch\u00ednh l\u00e0 t\u0103ng c\u01b0\u1eddng t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf synap c\u1ee7a GABA \u1edf n\u00e3o. Phenobarbital c\u0169ng \u0111\u01b0\u1ee3c ch\u1ee9ng minh c\u00f3 kh\u1ea3 n\u0103ng b\u1eaft ch\u01b0\u1edbc GABA.<\/span><\/p>\n
Phenobarbital c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 bilirubin huy\u1ebft \u1edf tr\u1ebb s\u01a1 sinh ho\u1eb7c b\u1ec7nh nh\u00e2n t\u0103ng bilirubin kh\u00f4ng li\u00ean h\u1ee3p.<\/span><\/p>\n
\u0110\u1eb7c t\u00ednh d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/span><\/h3>\n
Thu\u1ed1c \u0111\u01b0\u1ee3c h\u1ea5p thu ch\u1eadm \u1edf \u1ed1ng ti\u00eau h\u00f3a.<\/span><\/p>\n
Kh\u1ea3 n\u0103ng li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 50% \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 cao h\u01a1n \u1edf tr\u1ebb nh\u1ecf.<\/span><\/p>\n
Phenobarbital c\u00f3 kh\u1ea3 n\u0103ng ph\u00e2n b\u1ed1 r\u1ed9ng trong c\u00e1c m\u00f4 v\u00e0 n\u00e3o v\u00ec \u0111\u1eb7c t\u00ednh d\u1ec5 tan trong n\u01b0\u1edbc.<\/span><\/p>\n
Thu\u1ed1c \u0111\u01b0\u1ee3c hydroxyl h\u00f3a v\u00e0 li\u00ean h\u1ee3p t\u1ea1i gan.<\/span><\/p>\n
Phenobarbital \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u.<\/span><\/p>\n
Thu\u1ed1c Garnotal 100mg tr\u1ecb b\u1ec7nh g\u00ec?<\/span><\/h2>\n
\u0110\u1ed9ng kinh (kh\u00f4ng bao g\u1ed3m c\u01a1n \u0111\u1ed9ng kinh nh\u1ecf):<\/span><\/p>\n
\n
\u0110\u1ed9ng kinh c\u01a1n l\u1edbn.<\/span><\/li>\n
\u0110\u1ed9ng kinh gi\u1eadt c\u01a1.<\/span><\/li>\n
\u0110\u1ed9ng kinh c\u1ee5c b\u1ed9.<\/span><\/li>\n<\/ul>\n
D\u1ef1 ph\u00f2ng co gi\u1eadt do s\u1ed1t cao \u1edf tr\u1ebb nh\u1ecf.<\/span><\/p>\n
V\u00e0ng da s\u01a1 sinh.<\/span><\/p>\n
B\u1ec7nh nh\u00e2n t\u0103ng bilirubin huy\u1ebft kh\u00f4ng li\u00ean h\u1ee3p b\u1ea9m sinh, kh\u00f4ng tan huy\u1ebft b\u1ea9m sinh, b\u1ec7nh nh\u00e2n \u1ee9 m\u1eadt m\u1ea1n t\u00ednh trong gan.<\/span><\/p>\n
Li\u1ec1u d\u00f9ng thu\u1ed1c Garnotal 100mg<\/span><\/h2>\n
Ng\u01b0\u1eddi l\u1edbn<\/span><\/h3>\n\n\n\n\n\n\n\n\n
Ch\u1ec9 \u0111\u1ecbnh<\/span><\/td>\n Li\u1ec1u l\u01b0\u1ee3ng<\/span><\/td>\n<\/tr>\n
Ch\u1ed1ng co gi\u1eadt<\/span><\/td>\n 1-6 mg\/kg\/ng\u00e0y, u\u1ed1ng l\u00e0m 1 ho\u1eb7c nhi\u1ec1u l\u1ea7n<\/span><\/td>\n<\/tr>\n
An th\u1ea7n<\/span><\/td>\n 2mg\/kg, chia l\u00e0m 3 l\u1ea7n<\/span><\/td>\n<\/tr>\n
Tr\u01b0\u1edbc khi ph\u1eabu thu\u1eadt<\/span><\/td>\n 1-3mg\/kg<\/span><\/td>\n<\/tr>\n
Ch\u1ed1ng t\u0103ng bilirubin huy\u1ebft\u00a0<\/span><\/td>\n 5-10mg\/kg\/ng\u00e0y<\/span><\/td>\n<\/tr>\n
Tr\u1ebb em t\u1edbi 12 tu\u1ed5i<\/span><\/td>\n 1-4mg\/kg, chia l\u00e0m 3 l\u1ea7n m\u1ed7i ng\u00e0y<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Tr\u1ebb em<\/span><\/h3>\n\n\n\n\n\n\n\n
Ch\u1ec9 \u0111\u1ecbnh<\/span><\/td>\n Li\u1ec1u l\u01b0\u1ee3ng<\/span><\/td>\n<\/tr>\n
Ch\u1ed1ng co gi\u1eadt<\/span><\/td>\n 60-250mg\/ng\u00e0y, c\u00f3 th\u1ec3 u\u1ed1ng 1 l\u1ea7n ho\u1eb7c chia l\u00e0m nhi\u1ec1u l\u1ea7n trong ng\u00e0y<\/span><\/td>\n<\/tr>\n
An th\u1ea7n<\/span><\/td>\n 30-120mg\/ng\u00e0y, chia l\u00e0m 2-3 l\u1ea7n<\/span><\/td>\n<\/tr>\n
G\u00e2y ng\u1ee7<\/span><\/td>\n 100-320 mg, u\u1ed1ng tr\u01b0\u1edbc khi \u0111i ng\u1ee7. Kh\u00f4ng s\u1eed d\u1ee5ng qu\u00e1 2 tu\u1ea7n<\/span><\/td>\n<\/tr>\n
Ch\u1ed1ng t\u0103ng bilirubin huy\u1ebft<\/span><\/td>\n 30-60mg, chia l\u00e0m 3 l\u1ea7n<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Garnotal 100mg kh\u00f4ng d\u00f9ng trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n
Qu\u00e1 m\u1eabn v\u1edbi phenobarbital.<\/span><\/p>\n
Suy h\u00f4 h\u1ea5p n\u1eb7ng.<\/span><\/p>\n
Kh\u00f3 th\u1edf.<\/span><\/p>\n
T\u1eafc ngh\u1ebdn \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p.<\/span><\/p>\n
R\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a porphyrin.<\/span><\/p>\n
Suy gan n\u1eb7ng.<\/span><\/p>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng Garnotal 100mg<\/span><\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
Kh\u00f4ng d\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t.<\/span><\/p>\n
U\u1ed1ng thu\u1ed1c \u0111\u1ec1u \u0111\u1eb7n h\u00e0ng ng\u00e0y:<\/span><\/p>\n
\u1ede ng\u01b0\u1eddi l\u1edbn: H\u1ea1 li\u1ec1u sau 6 th\u00e1ng n\u1ebfu kh\u00f4ng c\u00f2n \u0111\u1ed9ng kinh, ng\u1eebng thu\u1ed1c sau 2 n\u0103m n\u1ebfu kh\u00f4ng c\u00f2n \u0111\u1ed9ng kinh.<\/span><\/p>\n
Tr\u1ebb em: H\u1ea1 li\u1ec1u v\u00e0 ng\u1eebng thu\u1ed1c sau 3 th\u00e1ng kh\u00f4ng c\u00f2n c\u01a1n.<\/span><\/p>\n
Hi\u1ec7u ch\u1ec9nh li\u1ec1u \u1edf nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t: Ng\u01b0\u1eddi suy gan, suy th\u1eadn, ng\u01b0\u1eddi gi\u00e0, ng\u01b0\u1eddi nghi\u1ec7n r\u01b0\u1ee3u.<\/span><\/p>\n
Kh\u00f4ng u\u1ed1ng thu\u1ed1c c\u00f9ng v\u1edbi r\u01b0\u1ee3u v\u00e0 n\u01b0\u1edbc gi\u1ea3i kh\u00e1t.<\/span><\/p>\n
Ng\u01b0\u1eddi m\u1eb9 c\u1ea7n d\u1ef1 ph\u00f2ng vitamin K trong v\u00f2ng 1 th\u00e1ng tr\u01b0\u1edbc sinh v\u00e0 cho tr\u1ebb d\u00f9ng \u0111\u1ed3ng th\u1eddi khi m\u1edbi sinh v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m cho tr\u1ebb b\u1ecb h\u1ed9i ch\u1ee9ng ch\u1ea3y m\u00e1u trong v\u00f2ng 24 gi\u1edd sau khi sinh n\u1ebfu ng\u01b0\u1eddi m\u1eb9 \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1eb1ng phenobarbital.<\/span><\/p>\n
T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/span><\/h3>\n
Th\u01b0\u1eddng g\u1eb7p: Bu\u1ed3n ng\u1ee7, m\u00e1u h\u1ed3ng c\u1ea7u kh\u1ed5ng l\u1ed3, gi\u1eadt rung nh\u00e3n c\u1ea7u, k\u00edch th\u00edch, lo l\u1eafng, l\u00fa l\u1eabn \u1edf ng\u01b0\u1eddi l\u1edbn tu\u1ed5i, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng.<\/span><\/p>\n
\u00cdt g\u1eb7p: C\u00f2i x\u01b0\u01a1ng, lo\u1ea1n d\u01b0\u1ee1ng \u0111au c\u01a1, r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a porphyrin, h\u1ed9i ch\u1ee9ng Lyell.<\/span><\/p>\n
Hi\u1ebfm g\u1eb7p: Thi\u1ebfu m\u00e1u h\u1ed3ng c\u1ea7u kh\u1ed5ng l\u1ed3 do thi\u1ebfu h\u1ee5t acid folic.<\/span><\/p>\n
T\u01b0\u01a1ng t\u00e1c<\/span><\/h3>\n
Kh\u00f4ng n\u00ean ph\u1ed1i h\u1ee3p v\u1edbi r\u01b0\u1ee3u, methotrexat, phenytoin v\u00ec c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n \u0111\u1ed9c t\u00ednh.<\/span><\/p>\n
Th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a b\u1edfi enzym gan.<\/span><\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n
Tri\u1ec7u ch\u1ee9ng: Th\u1edf ch\u1eadm, ng\u1eebng h\u00f4 h\u1ea5p, tr\u1ee5y m\u1ea1ch v\u00e0 t\u1eed vong.<\/span><\/p>\n
X\u1eed tr\u00ed: \u0110i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 cho ng\u01b0\u1eddi b\u1ec7nh.<\/span><\/p>\n
Thu\u1ed1c Garnotal 100mg mua \u1edf \u0111\u00e2u? gi\u00e1 bao nhi\u00eau?<\/span><\/h2>\n
Gi\u00e1 thu\u1ed1c Garnotal 100mg l\u00e0 800.000 \u0111\u1ed3ng\/ 1 h\u1ed9p v\u00e0 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, ch\u00fang t\u00f4i giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/span><\/p>\n
T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Garnotal 100mg?<\/span><\/h2>\n\n\n\n\n
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\u01afu \u0111i\u1ec3m<\/p>\n<\/td>\n
Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
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Thu\u1ed1c Garnotal 100mg l\u00e0 s\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t tr\u00ean d\u00e2y chuy\u1ec1n hi\u1ec7n \u0111\u1ea1i, quy tr\u00ecnh ki\u1ec3m nghi\u1ec7m kh\u1eaft khe, \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng.<\/li>\n
Thu\u1ed1c do \u0111\u01a1n v\u1ecb d\u01b0\u1ee3c ph\u1ea9m trong n\u01b0\u1edbc s\u1ea3n xu\u1ea5t n\u00ean gi\u00e1 th\u00e0nh \u1ed5n \u0111\u1ecbnh, d\u1ec5 d\u00e0ng t\u00ecm mau tr\u00ean th\u1ecb tr\u01b0\u1eddng.<\/li>\n
C\u00e1c nh\u00e0 kh\u1ecfa h\u1ecdc \u0111\u00e3 k\u1ebft lu\u1eadn r\u1eb1ng phenobarbital ti\u00eam t\u0129nh m\u1ea1ch tu\u1ea7n t\u1ef1 ki\u1ec3m so\u00e1t c\u00e1c c\u01a1n co gi\u1eadt \u1edf c\u1ea3 tr\u1ebb s\u01a1 sinh \u0111\u1ee7 th\u00e1ng v\u00e0 non th\u00e1ng (77%). Hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb n\u00e0y ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u l\u01b0\u1ee3ng nh\u01b0ng \u1ed5n \u0111\u1ecbnh \u1edf n\u1ed3ng \u0111\u1ed9 huy\u1ebft thanh l\u00e0 40 microgam\/mL.<\/li>\n<\/ul>\n<\/td>\n
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Bu\u1ed3n ng\u1ee7 c\u00f3 th\u1ec3 x\u1ea3y ra trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n
\n
T\u00e1c gi\u1ea3 J T Gilman v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng n\u0103m 1989). <\/span>Rapid sequential phenobarbital treatment of neonatal seizures<\/span><\/em>. Truy c\u1eadp ng\u00e0y 7 th\u00e1ng 7 n\u0103m 2023 t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/2717283\/<\/a><\/span><\/li>\n
T\u00e1c gi\u1ea3 M P De Carolis v\u00e0 c\u1ed9ng s\u1ef1 (Ng\u00e0y \u0111\u0103ng n\u0103m 1989). <\/span>Phenobarbital for treatment of seizures in preterm infant: a new administration scheme<\/span><\/em>. Truy c\u1eadp ng\u00e0y 7 th\u00e1ng 7 n\u0103m 2023 t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/2630236\/<\/a><\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
Thu\u1ed1c Garnotal 100mg v\u1edbi th\u00e0nh ph\u1ea7n ch\u1ee9a phenobarbital h\u00e0m l\u01b0\u1ee3ng 100mg, th\u01b0\u1eddng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr b\u1ec7nh \u0111\u1ed9ng kinh, v\u00e0ng da, d\u1ef1 ph\u00f2ng s\u1ed1t \u1edf tr\u1ebb s\u01a1 sinh<\/p>\n","protected":false},"author":1,"featured_media":35622,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-35621","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/35621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=35621"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/35622"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=35621"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=35621"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=35621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Th\u00e0nh ph\u1ea7n<\/h3>\nThu\u1ed1c Garnotal 100mg<\/strong> l\u00e0 thu\u1ed1c ch\u1ed1ng co gi\u1eadt v\u1edbi th\u00e0nh ph\u1ea7n ch\u1ee9a:<\/span><\/p>\nPhenobarbital 100mg \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n.<\/span><\/p>\n

Th\u00e0nh ph\u1ea7n<\/h3>\n
Thu\u1ed1c Garnotal 100mg<\/strong> l\u00e0 thu\u1ed1c ch\u1ed1ng co gi\u1eadt v\u1edbi th\u00e0nh ph\u1ea7n ch\u1ee9a:<\/span><\/p>\n
Phenobarbital 100mg \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n.<\/span><\/p>\n