{"id":164296,"date":"2026-10-27T13:30:02","date_gmt":"2026-10-27T06:30:02","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=164296"},"modified":"2026-10-27T13:31:46","modified_gmt":"2026-10-27T06:31:46","slug":"thuoc-tphplus-6mg-ml","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-tphplus-6mg-ml\/","title":{"rendered":"Tphplus 6mg\/ml"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Tphplus 6mg\/ml \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m c\u00f4ng ngh\u1ec7 cao Abipha c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893100763824<\/b><\/p>\n<h2>Tphplus 6mg\/ml l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i ml <b>Tphplus 6mg\/ml<\/b> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Fexofenadin hydroclorid: 6mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: H\u1ed7n d\u1ecbch u\u1ed1ng<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893100763824<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd x 50ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>Tphplus c\u00f3 ph\u1ea3i kh\u00e1ng sinh kh\u00f4ng?<\/h2>\n<p>Kh\u00f4ng, \u0111\u00e2y l\u00e0 thu\u1ed1c thu\u1ed9c nh\u00f3m kh\u00e1ng histamin<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Tphplus 6mg\/ml<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Fexofenadin gi\u00fap ki\u1ec3m so\u00e1t c\u00e1c bi\u1ec3u hi\u1ec7n d\u1ecb \u1ee9ng b\u1eb1ng c\u00e1ch h\u1ea1n ch\u1ebf t\u00e1c \u0111\u1ed9ng c\u1ee7a histamin l\u00ean th\u1ee5 th\u1ec3 H\u2081 n\u1eb1m ngo\u00e0i h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng, qua \u0111\u00f3 l\u00e0m gi\u1ea3m \u0111\u00e1p \u1ee9ng d\u1ecb \u1ee9ng t\u1ea1i \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, m\u1ea1ch m\u00e1u v\u00e0 h\u1ec7 ti\u00eau h\u00f3a. Ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c h\u00ecnh th\u00e0nh t\u1eeb qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a terfenadin v\u00e0 v\u1eabn gi\u1eef kh\u1ea3 n\u0103ng kh\u00e1ng histamin, nh\u01b0ng kh\u00f4ng g\u00e2y \u0111\u1ed9c t\u00ednh tr\u00ean tim theo c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf k\u00eanh kali tham gia \u0111i\u1ec1u h\u00f2a \u0111i\u1ec7n th\u1ebf m\u00e0ng trong giai \u0111o\u1ea1n t\u00e1i c\u1ef1c c\u1ee7a t\u1ebf b\u00e0o c\u01a1 tim. B\u00ean c\u1ea1nh \u0111\u00f3, thu\u1ed1c \u00edt \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c th\u1ee5 th\u1ec3 dopamin, acetylcholin v\u00e0 th\u1ee5 th\u1ec3 adrenergic alpha, beta. \u1ede li\u1ec1u \u0111i\u1ec1u tr\u1ecb, fexofenadin \u00edt \u0111i qua h\u00e0ng r\u00e0o m\u00e1u n\u00e3o n\u00ean th\u01b0\u1eddng kh\u00f4ng g\u00e2y an th\u1ea7n \u0111\u00e1ng k\u1ec3; hi\u1ec7u qu\u1ea3 kh\u00e1ng d\u1ecb \u1ee9ng c\u00f3 th\u1ec3 k\u00e9o d\u00e0i nh\u1edd s\u1ef1 g\u1eafn k\u1ebft v\u1edbi th\u1ee5 th\u1ec3 H\u2081 t\u01b0\u01a1ng \u0111\u1ed1i b\u1ec1n v\u00e0 qu\u00e1 tr\u00ecnh t\u00e1ch kh\u1ecfi th\u1ee5 th\u1ec3 di\u1ec5n ra ch\u1eadm.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Hi\u1ec7u qu\u1ea3 kh\u00e1ng histamin c\u1ee7a fexofenadin c\u00f3 th\u1ec3 duy tr\u00ec h\u01a1n n\u1eeda ng\u00e0y sau m\u1ed9t l\u1ea7n u\u1ed1ng. Trong c\u01a1 th\u1ec3, thu\u1ed1c \u0111\u1ea1t m\u1ee9c n\u1ed3ng \u0111\u1ed9 cao nh\u1ea5t trong huy\u1ebft t\u01b0\u01a1ng v\u00e0o kho\u1ea3ng gi\u1edd th\u1ee9 2-3, c\u00f2n t\u00e1c d\u1ee5ng gi\u1ea3m tri\u1ec7u ch\u1ee9ng d\u1ecb \u1ee9ng th\u01b0\u1eddng b\u1eaft \u0111\u1ea7u nh\u1eadn th\u1ea5y sau kho\u1ea3ng 60 ph\u00fat. N\u1ebfu d\u00f9ng c\u00f9ng b\u1eefa \u0103n nhi\u1ec1u ch\u1ea5t b\u00e9o, l\u01b0\u1ee3ng thu\u1ed1c \u0111\u1ea1t \u0111\u01b0\u1ee3c trong huy\u1ebft t\u01b0\u01a1ng t\u1ea1i \u0111\u1ec9nh c\u00f3 th\u1ec3 th\u1ea5p h\u01a1n kho\u1ea3ng 17%, \u0111\u1ed3ng th\u1eddi th\u1eddi \u0111i\u1ec3m \u0111\u1ea1t m\u1ee9c n\u00e0y c\u00f3 th\u1ec3 ch\u1eadm l\u1ea1i \u0111\u1ebfn kho\u1ea3ng 4 gi\u1edd.<\/p>\n<p>Fexofenadin ph\u00e2n b\u1ed1 ch\u1ee7 y\u1ebfu trong h\u1ec7 tu\u1ea7n ho\u00e0n v\u00e0 c\u00f3 kho\u1ea3ng 60-70% l\u01b0\u1ee3ng thu\u1ed1c li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, \u0111\u1eb7c bi\u1ec7t l\u00e0 albumin c\u00f9ng alpha-1 acid glycoprotein. Thu\u1ed1c kh\u00f3 \u0111i v\u00e0o m\u00f4 n\u00e3o do kh\u00f4ng v\u01b0\u1ee3t qua h\u00e0ng r\u00e0o m\u00e1u-n\u00e3o. Hi\u1ec7n v\u1eabn ch\u01b0a x\u00e1c \u0111\u1ecbnh ch\u1eafc ch\u1eafn fexofenadin c\u00f3 truy\u1ec1n qua nhau thai ho\u1eb7c \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft tr\u1ef1c ti\u1ebfp v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng; d\u00f9 v\u1eady, ho\u1ea1t ch\u1ea5t n\u00e0y t\u1eebng \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong s\u1eefa m\u1eb9 \u1edf ng\u01b0\u1eddi s\u1eed d\u1ee5ng terfenadin, v\u1ed1n \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh fexofenadin trong c\u01a1 th\u1ec3.<\/p>\n<p>Fexofenadin \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf kh\u1ecfi c\u01a1 th\u1ec3 ch\u1ee7 y\u1ebfu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, v\u1edbi kho\u1ea3ng 80% li\u1ec1u d\u00f9ng t\u00ecm th\u1ea5y trong ph\u00e2n v\u00e0 11-12% \u0111\u01b0\u1ee3c th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u \u1edf d\u1ea1ng nguy\u00ean v\u1eb9n. Thu\u1ed1c \u00edt tr\u1ea3i qua bi\u1ebfn \u0111\u1ed5i sinh h\u1ecdc: ph\u1ea7n chuy\u1ec3n h\u00f3a t\u1ea1i gan ch\u1ec9 chi\u1ebfm kho\u1ea3ng 0,5-1,5% li\u1ec1u d\u00f9ng nh\u1edd enzym cytochrom P450, t\u1ea1o ra c\u00e1c ch\u1ea5t kh\u00f4ng c\u00f2n ho\u1ea1t t\u00ednh; n\u1ebfu t\u00ednh c\u1ea3 qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a, t\u1ef7 l\u1ec7 t\u1ed5ng th\u1ec3 v\u00e0o kho\u1ea3ng 5%, ph\u1ea7n l\u1edbn di\u1ec5n ra \u1edf ni\u00eam m\u1ea1c ru\u1ed9t. B\u00ean c\u1ea1nh \u0111\u00f3, kho\u1ea3ng 3,5% li\u1ec1u thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a theo con \u0111\u01b0\u1eddng pha II \u0111\u1ed9c l\u1eadp v\u1edbi h\u1ec7 enzym cytochrom P450, t\u1ea1o th\u00e0nh d\u1eabn ch\u1ea5t methyl este ch\u1ec9 ph\u00e1t hi\u1ec7n trong ph\u00e2n, cho th\u1ea5y vi khu\u1ea9n \u0111\u01b0\u1eddng ru\u1ed9t c\u00f3 th\u1ec3 g\u00f3p ph\u1ea7n v\u00e0o qu\u00e1 tr\u00ecnh n\u00e0y. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a thu\u1ed1c th\u01b0\u1eddng kho\u1ea3ng 14,4 gi\u1edd, nh\u01b0ng \u1edf ng\u01b0\u1eddi suy th\u1eadn c\u00f3 th\u1ec3 k\u00e9o d\u00e0i th\u00eam kho\u1ea3ng 31-72%.<\/p>\n<h2>Thu\u1ed1c Tphplus 6mg\/ml \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Ch\u1ec9 \u0111\u1ecbnh nh\u1eb1m gi\u1ea3m kh\u00f3 ch\u1ecbu do d\u1ecb \u1ee9ng th\u1eddi ti\u1ebft, d\u1ecb \u1ee9ng h\u00f4 h\u1ea5p hay n\u1ed5i m\u1ec1 \u0111ay dai d\u1eb3ng kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n. Thu\u1ed1c Tphplus h\u1ed7 tr\u1ee3 c\u1ea3i thi\u1ec7n c\u00e1c t\u00ecnh tr\u1ea1ng sau:<\/p>\n<ul>\n<li>Ng\u1ee9a h\u1ecdng, ng\u1ee9a m\u0169i<\/li>\n<li>N\u1ed5i m\u1ea9n \u0111\u1ecf, ng\u1ee9a ng\u00e1y, m\u1ec1 \u0111ay<\/li>\n<li>Ch\u1ea3y n\u01b0\u1edbc m\u1eaft, ng\u1ee9a m\u1eaft<\/li>\n<li>Ch\u1ea3y d\u1ecbch m\u0169i, h\u1eaft h\u01a1i li\u00ean t\u1ee5c<\/li>\n<\/ul>\n<figure id=\"attachment_164305\" aria-describedby=\"caption-attachment-164305\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-164305\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/tphplus-6mg-ml.jpg\" alt=\"Tphplus 6mg\/ml\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/tphplus-6mg-ml.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/tphplus-6mg-ml-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/tphplus-6mg-ml-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/tphplus-6mg-ml-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/tphplus-6mg-ml-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-164305\" class=\"wp-caption-text\">Thu\u1ed1c Tphplus 6mg\/ml c\u00f3 t\u00e1c d\u1ee5ng tr\u1ecb vi\u00eam m\u0169i d\u1ecb \u1ee9ng v\u00e0 m\u1ec1 \u0111ay m\u1ea1n t\u00ednh<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Vi\u00eam m\u0169i d\u1ecb \u1ee9ng: D\u00f9ng thu\u1ed1c 2 l\u1ea7n m\u1ed7i ng\u00e0y, v\u1edbi li\u1ec1u 5 ml\/l\u1ea7n \u1edf tr\u1ebb t\u1eeb 2-11 tu\u1ed5i v\u00e0 10 ml\/l\u1ea7n \u1edf ng\u01b0\u1eddi t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean.<\/p>\n<p>M\u00e0y \u0111ay m\u1ea1n t\u00ednh v\u00f4 c\u0103n: Li\u1ec1u d\u00f9ng t\u01b0\u01a1ng t\u1ef1 vi\u00eam m\u0169i d\u1ecb \u1ee9ng \u1edf ng\u01b0\u1eddi t\u1eeb 2 tu\u1ed5i tr\u1edf l\u00ean. Ri\u00eang tr\u1ebb t\u1eeb 6 th\u00e1ng \u0111\u1ebfn d\u01b0\u1edbi 2 tu\u1ed5i s\u1eed d\u1ee5ng 2,5 ml\/l\u1ea7n, ng\u00e0y 2 l\u1ea7n.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i v\u00e0 ng\u01b0\u1eddi suy th\u1eadn: Li\u1ec1u d\u00f9ng Fexofenadin hydroclorid c\u1ea7n \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc theo ch\u1ee9c n\u0103ng th\u1eadn. Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb t\u1eeb 12 tu\u1ed5i b\u1ecb suy th\u1eadn b\u1eaft \u0111\u1ea7u v\u1edbi 10ml\/ng\u00e0y; tr\u1ebb 2-11 tu\u1ed5i d\u00f9ng 5 ml\/ng\u00e0y, c\u00f2n tr\u1ebb t\u1eeb 6 th\u00e1ng \u0111\u1ebfn d\u01b0\u1edbi 2 tu\u1ed5i d\u00f9ng 2,5 ml\/ng\u00e0y.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p><strong>H\u1ed7n d\u1ecbch Tphplus 6mg\/ml<\/strong> \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, tr\u01b0\u1edbc ho\u1eb7c sau b\u1eefa \u0103n nh\u01b0ng kh\u00f4ng \u0111\u01b0\u1ee3c c\u00f9ng n\u01b0\u1edbc \u00e9p tr\u00e1i c\u00e2y v\u00e0 c\u1ea7n c\u00e1ch th\u1eddi \u0111i\u1ec3m d\u00f9ng thu\u1ed1c kh\u00e1ng acid ch\u1ee9a nh\u00f4m ho\u1eb7c magnesi \u00edt nh\u1ea5t 15 ph\u00fat<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Tphplus 6mg\/ml trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng hay k\u00edch \u1ee9ng v\u1edbi c\u00e1c ho\u1ea1t ch\u1ea5t nh\u01b0 terfenadin, fexofenadin ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c\/th\u00e0nh ph\u1ea7n n\u00e0o c\u00f3 trong thu\u1ed1c Tphplus<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>S\u1ef1 c\u00f3 m\u1eb7t c\u1ee7a sorbitol d\u1ec5 d\u1eabn \u0111\u1ebfn m\u1ed9t s\u1ed1 v\u1ea5n \u0111\u1ec1 \u1edf \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng h\u1ed7 tr\u1ee3 nhu\u1eadn tr\u00e0ng nh\u1eb9<\/p>\n<p>Vi\u1ec7c d\u00f9ng thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m cho t\u00ecnh tr\u1ea1ng b\u1ec7nh v\u1ea9y n\u1ebfn ti\u1ebfn tri\u1ec3n x\u1ea5u h\u01a1n.<\/p>\n<p>S\u1ea3n ph\u1ea9m n\u00e0y c\u00f3 ch\u1ee9a sorbitol n\u00ean nh\u1eefng ai b\u1ecb ch\u1ee9ng kh\u00f4ng h\u1ea5p thu fructose do di truy\u1ec1n tuy\u1ec7t \u0111\u1ed1i tr\u00e1nh d\u00f9ng.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p c\u1ea7n l\u00e0m c\u00e1c ki\u1ec3m tra d\u1ecb \u1ee9ng qua da th\u00ec b\u1eaft bu\u1ed9c ph\u1ea3i d\u1eebng u\u1ed1ng thu\u1ed1c tr\u01b0\u1edbc \u0111\u00f3 \u00edt nh\u1ea5t 24 \u0111\u1ebfn 48 ti\u1ebfng.<\/p>\n<p>T\u00e1c d\u1ee5ng c\u0169ng nh\u01b0 \u0111\u1ed9 an to\u00e0n c\u1ee7a thu\u1ed1c Tphplus ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c nh\u1eadn tr\u00ean \u0111\u1ed1i t\u01b0\u1ee3ng tr\u1ebb nh\u1ecf d\u01b0\u1edbi 6 th\u00e1ng tu\u1ed5i.<\/p>\n<p>Do kh\u1ea3 n\u0103ng l\u1ecdc b\u1ecb gi\u1ea3m l\u00e0m thu\u1ed1c t\u1ed3n \u0111\u1ecdng l\u00e2u h\u01a1n trong m\u00e1u, ng\u01b0\u1eddi b\u1ecb suy th\u1eadn c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh l\u1ea1i li\u1ec1u l\u01b0\u1ee3ng cho th\u00edch h\u1ee3p.<\/p>\n<p>Ng\u01b0\u1eddi gi\u00e0 tr\u00ean 65 tu\u1ed5i c\u0169ng ph\u1ea3i c\u1ea9n tr\u1ecdng v\u1ec1 li\u1ec1u d\u00f9ng v\u00ec ho\u1ea1t \u0111\u1ed9ng c\u1ee7a th\u1eadn th\u01b0\u1eddng \u0111\u00e3 suy gi\u1ea3m t\u1ef1 nhi\u00ean theo th\u1eddi gian.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: Bu\u1ed3n ng\u1ee7, kh\u00f3 ti\u00eau, bu\u1ed3n n\u00f4n, ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, hoa m\u1eaft, nh\u1ee9c \u0111\u1ea7u.<\/p>\n<p>\u00cdt g\u1eb7p: R\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7, c\u1ea3m gi\u00e1c bu\u1ed3n ng\u1ee7 s\u00e2u, \u0111au b\u1ee5ng, g\u1eb7p \u00e1c m\u1ed9ng, kh\u00f4 mi\u1ec7ng, s\u1ee3 h\u00e3i.<\/p>\n<p>Hi\u1ebfm g\u1eb7p ho\u1eb7c ch\u01b0a r\u00f5 t\u1ea7n su\u1ea5t: Kh\u00f3 th\u1edf, ng\u1ee9a ng\u00e1y, \u0111\u1ecf b\u1eebng m\u1eb7t, t\u1ee9c ng\u1ef1c, b\u1ecb n\u1ed5i m\u1ea9n, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng n\u1eb7ng g\u00e2y s\u01b0ng m\u1eb7t\/m\u00f4i\/l\u01b0\u1ee1i\/h\u1ecdng, n\u1ed5i m\u1ec1 \u0111ay.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Verapamil v\u00e0 c\u00e1c thu\u1ed1c t\u00e1c \u0111\u1ed9ng l\u00ean P-glycoprotein, b\u00ean c\u1ea1nh m\u1ed9t s\u1ed1 kh\u00e1ng sinh ho\u1eb7c thu\u1ed1c kh\u00e1ng n\u1ea5m, c\u00f3 th\u1ec3 khi\u1ebfn n\u1ed3ng \u0111\u1ed9 fexofenadin trong huy\u1ebft t\u01b0\u01a1ng t\u0103ng. D\u00f9 v\u1eady, erythromycin v\u00e0 ketoconazol kh\u00f4ng l\u00e0m k\u00e9o d\u00e0i kho\u1ea3ng QT theo th\u00f4ng tin t\u01b0\u01a1ng t\u00e1c \u0111\u01b0\u1ee3c n\u00eau.<\/p>\n<p>\u0110\u1ec3 tr\u00e1nh \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng h\u1ea5p thu thu\u1ed1c, kh\u00f4ng n\u00ean d\u00f9ng fexofenadin c\u00f9ng th\u1eddi \u0111i\u1ec3m v\u1edbi ch\u1ebf ph\u1ea9m kh\u00e1ng acid c\u00f3 ch\u1ee9a magnesi, nh\u00f4m; n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi c\u0169ng c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng thu\u1ed1c trong m\u00e1u.<\/p>\n<p>Fexofenadin c\u00f3 th\u1ec3 l\u00e0m thay \u0111\u1ed5i n\u1ed3ng \u0111\u1ed9 c\u1ee7a m\u1ed9t s\u1ed1 thu\u1ed1c d\u00f9ng k\u00e8m, bao g\u1ed3m thu\u1ed1c kh\u00e1ng cholinergic, thu\u1ed1c an th\u1ea7n t\u00e1c \u0111\u1ed9ng l\u00ean h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng v\u00e0 r\u01b0\u1ee3u.<\/p>\n<p>Rifampin, amphetamin, n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi v\u00e0 thu\u1ed1c kh\u00e1ng acid c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 fexofenadin. Ngo\u00e0i ra, c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf acetylcholinesterase t\u00e1c \u0111\u1ed9ng l\u00ean h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng fexofenadin trong m\u00e1u; \u1edf chi\u1ec1u ng\u01b0\u1ee3c l\u1ea1i, fexofenadin c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 nh\u00f3m thu\u1ed1c n\u00e0y c\u0169ng nh\u01b0 betahistin.<\/p>\n<p>Trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb b\u1eb1ng fexofenadin, n\u00ean l\u1ef1a ch\u1ecdn n\u01b0\u1edbc l\u1ecdc thay cho c\u00e1c lo\u1ea1i n\u01b0\u1edbc \u00e9p tr\u00e1i c\u00e2y nh\u01b0 t\u00e1o, cam hay b\u01b0\u1edfi, b\u1edfi nh\u1eefng th\u1ee9c u\u1ed1ng n\u00e0y c\u00f3 th\u1ec3 khi\u1ebfn kh\u1ea3 n\u0103ng h\u1ea5p thu thu\u1ed1c gi\u1ea3m \u0111\u1ebfn 36%; ngo\u00e0i ra, vi\u1ec7c u\u1ed1ng r\u01b0\u1ee3u c\u00f9ng thu\u1ed1c c\u0169ng c\u1ea7n tr\u00e1nh do c\u00f3 th\u1ec3 l\u00e0m t\u0103ng bi\u1ec3u hi\u1ec7n an th\u1ea7n, ch\u1eb3ng h\u1ea1n nh\u01b0 bu\u1ed3n ng\u1ee7.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>\u0110\u1ec3 \u0111\u1ea3m b\u1ea3o \u0111\u1ed9 an to\u00e0n, ph\u1ee5 n\u1eef \u0111ang trong thai k\u1ef3 ch\u1ec9 n\u00ean u\u1ed1ng fexofenadin khi t\u00e1c d\u1ee5ng ch\u1eefa tr\u1ecb d\u00e0nh cho m\u1eb9 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u00e0 v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi r\u1ee7i ro c\u00f3 th\u1ec3 x\u1ea3y ra cho b\u00e9, do d\u1eef li\u1ec7u l\u00e2m s\u00e0ng tr\u00ean ng\u01b0\u1eddi mang thai hi\u1ec7n v\u1eabn ch\u01b0a th\u1ef1c s\u1ef1 \u0111\u1ea7y \u0111\u1ee7.<\/p>\n<p>M\u1eb7c d\u00f9 ch\u01b0a ghi nh\u1eadn \u1ea3nh h\u01b0\u1edfng x\u1ea5u n\u00e0o \u1edf tr\u1ebb nh\u1ecf khi m\u1eb9 d\u00f9ng fexofenadin trong th\u1eddi gian nu\u00f4i con b\u1eb1ng s\u1eefa m\u1eb9, kh\u1ea3 n\u0103ng thu\u1ed1c \u0111i v\u00e0o s\u1eefa m\u1eb9 v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c l\u00e0m r\u00f5 ho\u00e0n to\u00e0n, do \u0111\u00f3 c\u00e1c b\u00e0 m\u1eb9 \u0111ang cho con b\u00fa n\u00ean h\u1ebft s\u1ee9c c\u00e2n nh\u1eafc v\u00e0 c\u1ea9n tr\u1ecdng n\u1ebfu c\u1ea7n s\u1eed d\u1ee5ng<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>D\u00f9 nguy c\u01a1 bu\u1ed3n ng\u1ee7 do fexofenadin g\u00e2y ra l\u00e0 t\u01b0\u01a1ng \u0111\u1ed1i th\u1ea5p, ng\u01b0\u1eddi d\u00f9ng v\u1eabn ph\u1ea3i t\u1eadp trung ch\u00fa \u00fd n\u1ebfu tham gia giao th\u00f4ng ho\u1eb7c th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c c\u1ea7n s\u1ef1 t\u1ec9nh t\u00e1o cao \u0111\u1ed9.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Hi\u1ec7n ch\u01b0a c\u00f3 nhi\u1ec1u d\u1eef li\u1ec7u x\u00e1c \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 \u0111\u1ed9c t\u00ednh c\u1ea5p c\u1ee7a fexofenadin; m\u1ed9t s\u1ed1 d\u1ea5u hi\u1ec7u c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n khi qu\u00e1 li\u1ec1u l\u00e0 kh\u00f4 mi\u1ec7ng, ch\u00f3ng m\u1eb7t ho\u1eb7c bu\u1ed3n ng\u1ee7.<\/p>\n<p>Vi\u1ec7c x\u1eed tr\u00ed ch\u1ee7 y\u1ebfu t\u1eadp trung v\u00e0o h\u1ed7 tr\u1ee3 ng\u01b0\u1eddi b\u1ec7nh v\u00e0 ki\u1ec3m so\u00e1t c\u00e1c tri\u1ec7u ch\u1ee9ng, \u0111\u1ed3ng th\u1eddi c\u00e2n nh\u1eafc lo\u1ea1i b\u1ecf l\u01b0\u1ee3ng thu\u1ed1c c\u00f2n t\u1ed3n t\u1ea1i trong \u0111\u01b0\u1eddng ti\u00eau h\u00f3a nh\u01b0ng ch\u01b0a \u0111\u01b0\u1ee3c h\u1ea5p thu b\u1eb1ng nh\u1eefng bi\u1ec7n ph\u00e1p th\u00edch h\u1ee3p.<\/p>\n<p>Do th\u1ea9m ph\u00e2n m\u00e1u ch\u1ec9 \u0111\u00e0o th\u1ea3i \u0111\u01b0\u1ee3c kho\u1ea3ng 1,7% l\u01b0\u1ee3ng thu\u1ed1c trong m\u00e1u n\u00ean ph\u01b0\u01a1ng ph\u00e1p n\u00e0y \u00edt c\u00f3 gi\u00e1 tr\u1ecb trong vi\u1ec7c lo\u1ea1i b\u1ecf fexofenadin v\u00e0 hi\u1ec7n c\u0169ng ch\u01b0a c\u00f3 ch\u1ea5t gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho thu\u1ed1c n\u00e0y<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Tphplus 6mg\/ml \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Tphplus 6mg\/ml trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Tphplus 6mg\/ml khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>Thu\u1ed1c Tphplus gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Tphplus 6mg\/ml hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Tphplus 6mg\/ml c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Tphplus 6mg\/ml t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Tphplus 6mg\/ml nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/axofen-50ml\/\">Axofen 50ml<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Fexofenadin Hydroclorid 6mg\/ml, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Aristopharma Ltd, \u0111i\u1ec1u tr\u1ecb vi\u00eam m\u0169i d\u1ecb \u1ee9ng<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/a-t-fexofenadin\/\">A.T Fexofenadin<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Fexofenadin Hydroclorid 30mg\/5ml, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Aristopharma Ltd, \u0111i\u1ec1u tr\u1ecb vi\u00eam m\u0169i d\u1ecb \u1ee9ng<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Tphplus 6mg\/ml \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/To-huong-dan-su-dung-tphplus-6mg-ml-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 27 th\u00e1ng 10 n\u0103m 2026<\/li>\n<li>Bernstein DI, Schoenwetter WF, Nathan RA, Storms W, Ahlbrandt R, Mason J (1997). Efficacy and safety of fexofenadine hydrochloride for treatment of seasonal allergic rhinitis. Ann Allergy Asthma Immunol. Truy c\u1eadp ng\u00e0y 27 th\u00e1ng 10 n\u0103m 2026 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9396979\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/9396979\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Tphplus 6mg\/ml h\u1ed7 tr\u1ee3 c\u1ea3i thi\u1ec7n nhanh c\u00e1c tri\u1ec7u ch\u1ee9ng vi\u00eam m\u0169i d\u1ecb \u1ee9ng theo m\u00f9a v\u00e0 d\u1ecb \u1ee9ng h\u00f4 h\u1ea5p nh\u01b0 h\u1eaft h\u01a1i, s\u1ed5 m\u0169i, ng\u1ee9a m\u1eaft, gi\u00fap gi\u1ea3m m\u1ea9n \u0111\u1ecf, ng\u1ee9a ng\u00e1y do n\u1ed5i m\u1ec1 \u0111ay m\u1ea1n t\u00ednh<\/p>\n","protected":false},"author":1,"featured_media":164302,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-164296","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/164296","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=164296"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/164302"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=164296"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=164296"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=164296"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}