{"id":164157,"date":"2026-10-26T11:01:57","date_gmt":"2026-10-26T04:01:57","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=164157"},"modified":"2026-10-26T11:03:59","modified_gmt":"2026-10-26T04:03:59","slug":"thuoc-febuliv-80mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-febuliv-80mg\/","title":{"rendered":"Febuliv 80mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Febuliv 80mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi RV Lifesciences Limited c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 890110776724<\/b><\/p>\n<h2>Febuliv 80mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i vi\u00ean <b>Febuliv 80mg<\/b> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Febuxostat: 80mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 890110776724<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Febuliv 80mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Trong c\u01a1 th\u1ec3 ng\u01b0\u1eddi, qu\u00e1 tr\u00ecnh ph\u00e2n h\u1ee7y purin t\u1ea1o ra acid uric qua chu\u1ed7i chuy\u1ec3n h\u00f3a g\u1ed3m hypoxanthin v\u00e0 xanthin, v\u1edbi s\u1ef1 tham gia x\u00fac t\u00e1c c\u1ee7a enzym xanthin oxidase (XO) \u1edf c\u1ea3 hai giai \u0111o\u1ea1n. Febuxostat c\u00f3 c\u1ea5u tr\u00fac d\u1eabn xu\u1ea5t 2-arylthiazol, l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng acid uric trong m\u00e1u nh\u1edd ng\u0103n ch\u1eb7n ho\u1ea1t \u0111\u1ed9ng c\u1ee7a enzym n\u00e0y. Ho\u1ea1t ch\u1ea5t thu\u1ed9c nh\u00f3m \u1ee9c ch\u1ebf XO kh\u00f4ng mang c\u1ea5u tr\u00fac purin (NP-SIXO), c\u00f3 \u00e1i l\u1ef1c \u1ee9c ch\u1ebf r\u1ea5t cao v\u1edbi gi\u00e1 tr\u1ecb Ki in vitro d\u01b0\u1edbi 1 nanomol, \u0111\u1ed3ng th\u1eddi t\u00e1c \u0111\u1ed9ng l\u00ean c\u1ea3 hai d\u1ea1ng oxy h\u00f3a v\u00e0 d\u1ea1ng kh\u1eed c\u1ee7a enzym. \u1ede m\u1ee9c n\u1ed3ng \u0111\u1ed9 \u0111\u1ea1t \u0111\u01b0\u1ee3c trong \u0111i\u1ec1u tr\u1ecb, febuxostat kh\u00f4ng \u1ee9c ch\u1ebf c\u00e1c enzym kh\u00e1c li\u00ean quan \u0111\u1ebfn chuy\u1ec3n h\u00f3a purin ho\u1eb7c pyrimidin, bao g\u1ed3m guanin deaminase, hypoxanthin-guanine phosphoribosyltransferase, orotate phosphoribosyltransferase, orotidine monophosphate decarboxylase v\u00e0 purin nucleoside phosphorylase.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>N\u1ed3ng \u0111\u1ed9 febuxostat trong huy\u1ebft t\u01b0\u01a1ng th\u01b0\u1eddng \u0111\u1ea1t \u0111\u1ec9nh trong v\u00f2ng 60-90 ph\u00fat sau khi u\u1ed1ng; l\u01b0\u1ee3ng ho\u1ea1t ch\u1ea5t \u0111\u01b0\u1ee3c h\u1ea5p thu \u01b0\u1edbc t\u00ednh kh\u00f4ng th\u1ea5p h\u01a1n 84%. V\u1edbi ph\u00e1c \u0111\u1ed3 d\u00f9ng m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh (Cmax) n\u1eb1m trong kho\u1ea3ng 2,8-3,2 \u00b5g\/mL \u1edf m\u1ee9c li\u1ec1u 80 mg v\u00e0 5,0-5,3 \u00b5g\/mL \u1edf m\u1ee9c li\u1ec1u 120 mg, theo d\u1eef li\u1ec7u t\u1eeb c\u1ea3 nghi\u00ean c\u1ee9u d\u00f9ng m\u1ed9t li\u1ec1u v\u00e0 d\u00f9ng nhi\u1ec1u li\u1ec1u. T\u1ef7 l\u1ec7 sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i c\u1ee7a vi\u00ean u\u1ed1ng ch\u01b0a c\u00f3 s\u1ed1 li\u1ec7u x\u00e1c \u0111\u1ecbnh.<\/p>\n<p>Th\u1ee9c \u0103n ch\u1ee9a nhi\u1ec1u ch\u1ea5t b\u00e9o c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u0169ng nh\u01b0 t\u1ed5ng l\u01b0\u1ee3ng thu\u1ed1c h\u1ea5p thu v\u00e0o m\u00e1u. M\u1eb7c d\u00f9 c\u00e1c th\u00f4ng s\u1ed1 h\u1ea5p thu thay \u0111\u1ed5i, t\u00e1c d\u1ee5ng gi\u1ea3m acid uric m\u00e1u khi s\u1eed d\u1ee5ng l\u1eb7p l\u1ea1i li\u1ec1u 80mg kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng. Do \u0111\u00f3, ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng c\u1ea7n quan t\u00e2m \u0111\u1ebfn th\u1eddi \u0111i\u1ec3m b\u1eefa \u0103n v\u00e0 c\u00f3 th\u1ec3 u\u1ed1ng thu\u1ed1c l\u00fac no hay \u0111\u00f3i \u0111\u1ec1u \u0111\u01b0\u1ee3c.<\/p>\n<p>D\u1eef li\u1ec7u d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc cho th\u1ea5y febuxostat c\u00f3 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 bi\u1ec3u ki\u1ebfn \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh kho\u1ea3ng 29-75 l\u00edt khi d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng v\u1edbi li\u1ec1u t\u1eeb 10 \u0111\u1ebfn 300 mg. Trong tu\u1ea7n ho\u00e0n, ch\u1ec9 kho\u1ea3ng 0,8% ho\u1ea1t ch\u1ea5t \u1edf d\u1ea1ng kh\u00f4ng li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng; ph\u1ea7n c\u00f2n l\u1ea1i ch\u1ee7 y\u1ebfu g\u1eafn v\u1edbi albumin. T\u1ef7 l\u1ec7 li\u00ean k\u1ebft n\u00e0y kh\u00f4ng bi\u1ebfn \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 khi n\u1ed3ng \u0111\u1ed9 thu\u1ed1c t\u01b0\u01a1ng \u1ee9ng v\u1edbi li\u1ec1u 80 mg ho\u1eb7c 120 mg. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh c\u0169ng li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng \u1edf m\u1ee9c cao, v\u1edbi t\u1ef7 l\u1ec7 ghi nh\u1eadn t\u1eeb 82% \u0111\u1ebfn 91%.<\/p>\n<p>Febuxostat \u0111\u01b0\u1ee3c x\u1eed l\u00fd t\u1ea1i gan th\u00f4ng qua ph\u1ea3n \u1ee9ng oxy h\u00f3a v\u00e0 li\u00ean h\u1ee3p glucuronid. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a hydroxyl c\u1ee7a febuxostat g\u1ed3m b\u1ed1n d\u1ea1ng c\u00f3 kh\u1ea3 n\u0103ng ph\u00e1t huy t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd, nh\u01b0ng ch\u1ec9 ba d\u1ea1ng \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n trong huy\u1ebft t\u01b0\u01a1ng \u1edf ng\u01b0\u1eddi. Qu\u00e1 tr\u00ecnh oxy h\u00f3a ch\u1ee7 y\u1ebfu li\u00ean quan \u0111\u1ebfn CYP1A1, CYP1A2, CYP2C8, CYP2C9; ph\u1ea3n \u1ee9ng glucuronid h\u00f3a ch\u1ee7 y\u1ebfu do UGT1A1, UGT1A8 v\u00e0 UGT1A9 x\u00fac t\u00e1c.<\/p>\n<p>Febuxostat \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua c\u1ea3 th\u1eadn v\u00e0 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Sau khi u\u1ed1ng 80 mg ho\u1ea1t ch\u1ea5t c\u00f3 \u0111\u00e1nh d\u1ea5u ph\u00f3ng x\u1ea1, kho\u1ea3ng 49% l\u01b0\u1ee3ng d\u00f9ng \u0111\u01b0\u1ee3c thu h\u1ed3i trong n\u01b0\u1edbc ti\u1ec3u v\u00e0 45% trong ph\u00e2n. Trong n\u01b0\u1edbc ti\u1ec3u, thu\u1ed1c nguy\u00ean v\u1eb9n chi\u1ebfm 3%, acyl glucuronid chi\u1ebfm 30%, c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a oxy h\u00f3a c\u00f9ng d\u1ea1ng li\u00ean h\u1ee3p chi\u1ebfm 13% v\u00e0 nh\u1eefng ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u01b0a x\u00e1c \u0111\u1ecbnh chi\u1ebfm 3%. T\u1ea1i ph\u00e2n, c\u00e1c t\u1ef7 l\u1ec7 t\u01b0\u01a1ng \u1ee9ng l\u1ea7n l\u01b0\u1ee3t l\u00e0 12%, 1%, 25% v\u00e0 7%.<\/p>\n<h2>Thu\u1ed1c Febuliv 80mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Febuxostat \u0111\u01b0\u1ee3c d\u00f9ng cho ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh m\u1eafc t\u0103ng acid uric m\u00e1u m\u1ea1n t\u00ednh c\u00f3 l\u1eafng \u0111\u1ecdng urat, bi\u1ec3u hi\u1ec7n qua s\u1ea1n urat ho\u1eb7c vi\u00eam kh\u1edbp g\u00fat \u0111ang m\u1eafc hay \u0111\u00e3 t\u1eebng x\u1ea3y ra.<\/p>\n<figure id=\"attachment_164264\" aria-describedby=\"caption-attachment-164264\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-164264\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/febuliv-80mg.jpg\" alt=\"Febuliv 80mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/febuliv-80mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/febuliv-80mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/febuliv-80mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/febuliv-80mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/febuliv-80mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-164264\" class=\"wp-caption-text\">Febuliv 80mg t\u0103ng acid uric m\u00e1u m\u1ea1n t\u00ednh c\u00f3 l\u1eafng \u0111\u1ecdng urat<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o: Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u01b0\u1eddng d\u00f9ng l\u00e0 1 vi\u00ean Febuliv lo\u1ea1i 80mg. Sau 2-4 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb, n\u1ebfu acid uric m\u00e1u ch\u01b0a gi\u1ea3m xu\u1ed1ng m\u1ee9c 6 mg\/dL (357 \u00b5mol\/L) ho\u1eb7c th\u1ea5p h\u01a1n, b\u00e1c s\u0129 c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc n\u00e2ng li\u1ec1u l\u00ean 120 mg\/ng\u00e0y.<\/p>\n<p>Theo d\u00f5i \u0111i\u1ec1u tr\u1ecb: N\u1ed3ng \u0111\u1ed9 acid uric m\u00e1u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u1ea1i sau 2 tu\u1ea7n k\u1ec3 t\u1eeb khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, c\u1ea7n ki\u1ec3m so\u00e1t ch\u1ec9 s\u1ed1 n\u00e0y \u1edf m\u1ee9c th\u1ea5p h\u01a1n 6 mg\/dL (357 \u00b5mol\/L) v\u00e0 duy tr\u00ec \u1ed5n \u0111\u1ecbnh trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>D\u1ef1 ph\u00f2ng c\u01a1n g\u00fat: Gi\u1eef acid uric huy\u1ebft thanh \u1ed5n \u0111\u1ecbnh \u1edf m\u1ee9c &lt; 6 mg\/dL ( 357 \u00b5mol\/L) v\u00e0 c\u1ea7n duy tr\u00ec c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba c\u01a1n g\u00fat c\u1ea5p trong th\u1eddi gian t\u1ed1i thi\u1ec3u 6 th\u00e1ng.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i, suy th\u1eadn nh\u1eb9-v\u1eeba: Ch\u1ec9 c\u1ea7n duy tr\u00ec li\u1ec1u nh\u01b0 ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng, kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh g\u00ec<\/p>\n<p>V\u1edbi tr\u01b0\u1eddng h\u1ee3p suy th\u1eadn n\u1eb7ng (\u0111\u1ed9 thanh th\u1ea3i creatinin d\u01b0\u1edbi 30 mL\/ph\u00fat), suy gan trung b\u00ecnh-n\u1eb7ng, ng\u01b0\u1eddi d\u01b0\u1edbi 18 tu\u1ed5i v\u00ec d\u1eef li\u1ec7u v\u1ec1 hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 an to\u00e0n c\u00f2n h\u1ea1n ch\u1ebf, c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng.<\/p>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o \u1edf ng\u01b0\u1eddi suy gan nh\u1eb9 l\u00e0 1 vi\u00ean Febuliv lo\u1ea1i h\u00e0m l\u01b0\u1ee3ng 80mg ng\u00e0y.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p><b>Vi\u00ean n\u00e9n Febuliv 80mg <\/b>\u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Febuliv 80mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi Febuxostat hay b\u1ea5t c\u1ee9 t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u00f3 trong Febuliv 80mg<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>\u1ede ng\u01b0\u1eddi m\u1eafc b\u1ec7nh tim thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 ho\u1eb7c suy tim sung huy\u1ebft, kh\u00f4ng khuy\u1ebfn c\u00e1o \u0111i\u1ec1u tr\u1ecb b\u1eb1ng febuxostat. M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u ghi nh\u1eadn s\u1ed1 bi\u1ebfn c\u1ed1 tim m\u1ea1ch cao h\u01a1n so v\u1edbi alopurinol, tuy nhi\u00ean ch\u01b0a x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c m\u1ed1i li\u00ean h\u1ec7 nh\u00e2n qu\u1ea3. C\u1ea7n c\u00e2n nh\u1eafc k\u1ef9 khi b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch ho\u1eb7c nh\u1ed3i m\u00e1u c\u01a1 tim.<\/p>\n<p>Vi\u1ec7c \u0111i\u1ec1u tr\u1ecb n\u00ean \u0111\u01b0\u1ee3c b\u1eaft \u0111\u1ea7u sau khi c\u01a1n g\u00fat c\u1ea5p \u0111\u00e3 h\u1ebft ho\u00e0n to\u00e0n. Trong \u00edt nh\u1ea5t 6 th\u00e1ng \u0111\u1ea7u, c\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p NSAID ho\u1eb7c colchicin \u0111\u1ec3 h\u1ea1n ch\u1ebf nguy c\u01a1 t\u00e1i ph\u00e1t. N\u1ebfu c\u01a1n g\u00fat xu\u1ea5t hi\u1ec7n khi \u0111ang d\u00f9ng febuxostat, c\u1ea7n x\u1eed tr\u00ed \u0111\u1ee3t c\u1ea5p th\u00edch h\u1ee3p v\u00e0 kh\u00f4ng t\u1ef1 \u00fd ng\u1eebng thu\u1ed1c.<\/p>\n<p>Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u \u0111\u1ec3 kh\u1eb3ng \u0111\u1ecbnh t\u00ednh an to\u00e0n c\u1ee7a febuxostat \u1edf ng\u01b0\u1eddi t\u0103ng s\u1ea3n xu\u1ea5t urat do b\u1ec7nh \u00e1c t\u00ednh, \u0111i\u1ec1u tr\u1ecb ung th\u01b0 ho\u1eb7c m\u1eafc h\u1ed9i ch\u1ee9ng Lesch-Nyhan n\u00ean kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p n\u00e0y.<\/p>\n<p>Do thi\u1ebfu kinh nghi\u1ec7m l\u00e2m s\u00e0ng tr\u00ean b\u1ec7nh nh\u00e2n gh\u00e9p t\u1ea1ng, vi\u1ec7c s\u1eed d\u1ee5ng febuxostat \u1edf nh\u00f3m \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o.<\/p>\n<p>Tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, n\u00ean \u0111\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng gan v\u00e0 ti\u1ebfp t\u1ee5c ki\u1ec3m tra \u0111\u1ecbnh k\u1ef3 t\u00f9y theo t\u00ecnh tr\u1ea1ng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng febuxostat cho ng\u01b0\u1eddi c\u00f3 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng tuy\u1ebfn gi\u00e1p, nh\u1ea5t l\u00e0 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb d\u00e0i h\u1ea1n.<\/p>\n<p>Ng\u01b0\u1eddi m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n di truy\u1ec1n hi\u1ebfm g\u1eb7p nh\u01b0 thi\u1ebfu men Lapp lactase, kh\u00f4ng dung n\u1ea1p galactose ho\u1eb7c k\u00e9m h\u1ea5p thu glucose-galactose kh\u00f4ng n\u00ean d\u00f9ng vi\u00ean thu\u1ed1c c\u00f3 ch\u1ee9a lactose.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ec7nh n\u00ean x\u00e1c \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 \u1ea3nh h\u01b0\u1edfng c\u1ee7a thu\u1ed1c \u0111\u1ebfn s\u1ef1 t\u1ec9nh t\u00e1o tr\u01b0\u1edbc khi l\u00e1i xe, v\u1eadn h\u00e0nh m\u00e1y m\u00f3c ho\u1eb7c th\u1ef1c hi\u1ec7n c\u00f4ng vi\u1ec7c c\u00f3 nguy c\u01a1 cao.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: \u0110au \u0111\u1ea7u, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a v\u1edbi bi\u1ec3u hi\u1ec7n ti\u00eau ch\u1ea3y ho\u1eb7c bu\u1ed3n n\u00f4n, t\u0103ng men gan ho\u1eb7c b\u1ea5t th\u01b0\u1eddng x\u00e9t nghi\u1ec7m ch\u1ee9c n\u0103ng gan, c\u01a1n g\u00fat c\u1ea5p xu\u1ea5t hi\u1ec7n ho\u1eb7c t\u00e1i ph\u00e1t, n\u1ed5i ban da.<\/p>\n<p>\u00cdt g\u1eb7p: Thay \u0111\u1ed5i hormon k\u00edch th\u00edch tuy\u1ebfn gi\u00e1p, vi\u00eam bao ho\u1ea1t d\u1ecbch, ti\u1ec3u m\u00e1u, t\u0103ng c\u00e2n, rung nh\u0129, thay \u0111\u1ed5i v\u1ecb gi\u00e1c, kh\u00f3 ti\u00eau, nhi\u1ec5m khu\u1ea9n h\u00f4 h\u1ea5p, gi\u1ea3m ham mu\u1ed1n t\u00ecnh d\u1ee5c, \u0111au kh\u1edbp, protein ni\u1ec7u, m\u1ec1 \u0111ay, ch\u00f3ng m\u1eb7t, tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n, t\u0103ng lipid m\u00e1u, kh\u00f3 th\u1edf, m\u1ea5t ng\u1ee7, y\u1ebfu c\u01a1, s\u1ecfi m\u1eadt, t\u00e1o b\u00f3n, ho, gi\u1ea3m kh\u1ee9u gi\u00e1c, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, \u0111au b\u1ee5ng, bu\u1ed3n ng\u1ee7, vi\u00eam ph\u1ebf qu\u1ea3n, co th\u1eaft c\u01a1, \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, gi\u1ea3m c\u1ea3m gi\u00e1c ngon mi\u1ec7ng, li\u1ec7t n\u1eeda ng\u01b0\u1eddi, kh\u00f4 mi\u1ec7ng, suy th\u1eadn, ph\u00e1t ban d\u00e1t s\u1ea7n, c\u0103ng c\u01a1, r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng, ti\u1ec3u d\u1eaft, thay \u0111\u1ed5i m\u00e0u da, gi\u1ea3m t\u1ec9nh t\u00e1o, vi\u00eam kh\u1edbp, \u0111\u1ea7y h\u01a1i, \u0111\u1ea1i ti\u1ec7n nhi\u1ec1u l\u1ea7n, kh\u00f3 ch\u1ecbu \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111au c\u01a1, xu\u1ea5t huy\u1ebft d\u01b0\u1edbi da, t\u1ed5n th\u01b0\u01a1ng da, \u1ee3 h\u01a1i, d\u1ecb c\u1ea3m.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: H\u1ed9i ch\u1ee9ng Stevens-Johnson, vi\u00eam t\u1ee5y, r\u1ee5ng t\u00f3c, vi\u00eam th\u1eadn m\u00f4 k\u1ebd, nh\u00ecn m\u1edd, t\u0103ng ti\u1ebft m\u1ed3 h\u00f4i, v\u00e0ng da, c\u1ee9ng kh\u1edbp, ch\u00e1n \u0103n, \u00f9 tai, ph\u00f9 m\u1ea1ch, ti\u00eau c\u01a1 v\u00e2n, gi\u1ea3m c\u00e2n, lo\u00e9t mi\u1ec7ng, vi\u00eam gan, ph\u00e1t ban tr\u00f3c v\u1ea3y, c\u1ee9ng c\u01a1, t\u0103ng c\u1ea3m gi\u00e1c ngon mi\u1ec7ng, t\u1ed5n th\u01b0\u01a1ng gan, ban \u0111\u1ecf, ti\u1ec3u d\u1eaft.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Mercaptopurin v\u00e0 azathioprin kh\u00f4ng n\u00ean d\u00f9ng chung v\u1edbi febuxostat v\u00ec s\u1ef1 \u1ee9c ch\u1ebf xanthin oxidase c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m chuy\u1ec3n h\u00f3a hai thu\u1ed1c, khi\u1ebfn n\u1ed3ng \u0111\u1ed9 trong m\u00e1u t\u0103ng v\u00e0 d\u1eabn \u0111\u1ebfn \u0111\u1ed9c t\u00ednh. T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a qua enzym n\u00e0y c\u0169ng nh\u01b0 thu\u1ed1c h\u00f3a tr\u1ecb g\u00e2y \u0111\u1ed9c t\u1ebf b\u00e0o hi\u1ec7n ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u \u0111\u00e1nh gi\u00e1.<\/p>\n<p>Rosiglitazon v\u00e0 c\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a qua CYP2C8 th\u01b0\u1eddng kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u khi d\u00f9ng c\u00f9ng febuxostat, do nghi\u00ean c\u1ee9u ch\u01b0a ph\u00e1t hi\u1ec7n thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 v\u1ec1 d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a rosiglitazon.<\/p>\n<p>Theophyllin c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u1ed1i h\u1ee3p v\u1edbi febuxostat 80 mg\/ng\u00e0y m\u00e0 kh\u00f4ng c\u1ea7n bi\u1ec7n ph\u00e1p \u0111i\u1ec1u ch\u1ec9nh \u0111\u1eb7c bi\u1ec7t, b\u1edfi ch\u01b0a ghi nh\u1eadn \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc ho\u1eb7c \u0111\u1ed9 an to\u00e0n c\u1ee7a theophyllin. D\u1eef li\u1ec7u ph\u1ed1i h\u1ee3p v\u1edbi febuxostat 120 mg\/ng\u00e0y hi\u1ec7n c\u00f2n thi\u1ebfu.<\/p>\n<p>Naproxen v\u00e0 c\u00e1c thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh glucuronid h\u00f3a c\u00f3 th\u1ec3 l\u00e0m thay \u0111\u1ed5i m\u1ee9c ph\u01a1i nhi\u1ec5m febuxostat. Khi d\u00f9ng naproxen, Cmax t\u0103ng 28%, AUC t\u0103ng 41% v\u00e0 th\u1eddi gian b\u00e1n th\u1ea3i k\u00e9o d\u00e0i 26%. D\u00f9 v\u1eady, ch\u01b0a ghi nh\u1eadn s\u1ef1 gia t\u0103ng ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng, n\u00ean th\u00f4ng th\u01b0\u1eddng kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u hai thu\u1ed1c.<\/p>\n<p>C\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng m\u1ea1nh UGT c\u00f3 th\u1ec3 th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a febuxostat v\u00e0 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t acid uric. N\u00ean x\u00e9t nghi\u1ec7m l\u1ea1i acid uric sau 1-2 tu\u1ea7n k\u1ec3 t\u1eeb khi b\u1eaft \u0111\u1ea7u ph\u1ed1i h\u1ee3p; khi ng\u1eebng thu\u1ed1c c\u1ea3m \u1ee9ng, n\u1ed3ng \u0111\u1ed9 febuxostat c\u00f3 th\u1ec3 t\u0103ng tr\u1edf l\u1ea1i.<\/p>\n<p>Colchicin, indomethacin, hydrochlorothiazid v\u00e0 warfarin c\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng febuxostat m\u00e0 kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u theo d\u1eef li\u1ec7u hi\u1ec7n c\u00f3. \u0110\u1ed1i v\u1edbi warfarin, vi\u1ec7c ph\u1ed1i h\u1ee3p kh\u00f4ng g\u00e2y thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 v\u1ec1 d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc, INR ho\u1eb7c ho\u1ea1t t\u00ednh y\u1ebfu t\u1ed1 VII.<\/p>\n<p>Desipramin v\u00e0 c\u00e1c c\u01a1 ch\u1ea5t CYP2D6 c\u00f3 th\u1ec3 ch\u1ecbu \u1ea3nh h\u01b0\u1edfng do febuxostat \u1ee9c ch\u1ebf nh\u1eb9 enzym CYP2D6. Khi d\u00f9ng febuxostat 120 mg\/ng\u00e0y, AUC c\u1ee7a desipramin t\u0103ng trung b\u00ecnh 22%; th\u00f4ng th\u01b0\u1eddng kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u c\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a qua enzym n\u00e0y.<\/p>\n<p>Thu\u1ed1c kh\u00e1ng acid ch\u1ee9a magnesi hydroxid ho\u1eb7c nh\u00f4m hydroxid l\u00e0m ch\u1eadm h\u1ea5p thu febuxostat kho\u1ea3ng 1 gi\u1edd v\u00e0 gi\u1ea3m Cmax kho\u1ea3ng 32%, nh\u01b0ng kh\u00f4ng l\u00e0m thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 AUC. V\u00ec v\u1eady, kh\u00f4ng nh\u1ea5t thi\u1ebft ph\u1ea3i b\u1ed1 tr\u00ed th\u1eddi \u0111i\u1ec3m u\u1ed1ng hai thu\u1ed1c c\u00e1ch xa nhau.<\/p>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u x\u00e1c \u0111\u1ecbnh kh\u1ea3 n\u0103ng t\u01b0\u01a1ng th\u00edch khi ph\u1ed1i h\u1ee3p febuxostat v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c, do \u0111\u00f3 kh\u00f4ng n\u00ean tr\u1ed9n chung c\u00e1c thu\u1ed1c.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ch\u01b0a c\u00f3 \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng l\u00e2m s\u00e0ng \u0111\u1ec3 k\u1ebft lu\u1eadn febuxostat an to\u00e0n cho thai ph\u1ee5. Do nh\u1eefng r\u1ee7i ro ti\u1ec1m \u1ea9n \u0111\u1ed1i v\u1edbi thai nhi ch\u01b0a \u0111\u01b0\u1ee3c l\u00e0m r\u00f5, thu\u1ed1c kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o d\u00f9ng trong giai \u0111o\u1ea1n n\u00e0y, m\u1eb7c d\u00f9 c\u00e1c th\u1eed nghi\u1ec7m tr\u00ean \u0111\u1ed9ng v\u1eadt ch\u01b0a ph\u00e1t hi\u1ec7n d\u1ea5u hi\u1ec7u g\u00e2y h\u1ea1i \u0111\u1ebfn kh\u1ea3 n\u0103ng sinh s\u1ea3n v\u00e0 s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a thai.<\/p>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng febuxostat trong giai \u0111o\u1ea1n n\u00e0y kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb do ch\u01b0a x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c l\u01b0\u1ee3ng thu\u1ed1c c\u00f3 th\u1ec3 truy\u1ec1n v\u00e0o s\u1eefa m\u1eb9 \u1edf ng\u01b0\u1eddi. D\u1eef li\u1ec7u th\u1ef1c nghi\u1ec7m tr\u00ean \u0111\u1ed9ng v\u1eadt cho th\u1ea5y thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua s\u1eefa v\u00e0 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u1ee7a con non.<\/p>\n<p>C\u00e1c th\u1eed nghi\u1ec7m ti\u1ec1n l\u00e2m s\u00e0ng kh\u00f4ng ghi nh\u1eadn thay \u0111\u1ed5i b\u1ea5t l\u1ee3i v\u1ec1 ch\u1ee9c n\u0103ng sinh s\u1ea3n \u1edf \u0111\u1ed9ng v\u1eadt khi d\u00f9ng febuxostat v\u1edbi li\u1ec1u l\u00ean t\u1edbi 48 mg\/kg\/ng\u00e0y. \u0110\u1ed1i v\u1edbi con ng\u01b0\u1eddi, t\u00e1c \u0111\u1ed9ng c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y l\u00ean kh\u1ea3 n\u0103ng th\u1ee5 thai hi\u1ec7n v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Khi s\u1eed d\u1ee5ng febuxostat, ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, t\u00ea ng\u1ee9a tay ch\u00e2n (d\u1ecb c\u1ea3m) ho\u1eb7c nh\u00ecn m\u1edd. \u0110\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n, n\u00ean t\u1ea1m d\u1eebng vi\u1ec7c l\u00e1i xe, \u0111\u1ee9ng m\u00e1y ho\u1eb7c l\u00e0m c\u00e1c c\u00f4ng vi\u1ec7c nguy hi\u1ec3m cho t\u1edbi khi bi\u1ebft ch\u1eafc thu\u1ed1c kh\u00f4ng g\u00e2y ra c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i n\u00eau tr\u00ean \u0111\u1ed1i v\u1edbi c\u01a1 th\u1ec3 m\u00ecnh.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Ch\u1ee7 y\u1ebfu x\u1eed l\u00fd tri\u1ec7u ch\u1ee9ng<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Febuliv 80mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Febuliv 80mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Febuliv 80mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>Thu\u1ed1c Febuliv 80mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Febuliv 80mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Febuliv 80mg c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Febuliv 80mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Febuliv 80mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/febustad-80\/\">Febustad 80 <\/a>c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Febuxostat 80mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm, \u0111i\u1ec1u tr\u1ecb t\u0103ng acid uric m\u00e1u m\u1ea1n t\u00ednh<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/febuxostat-5a-farma-80mg\/\">Febuxostat-5a Farma 80mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Febuxostat 80mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n li\u00ean doanh d\u01b0\u1ee3c ph\u1ea9m \u00c9loge France Vi\u1ec7t Nam, \u0111i\u1ec1u tr\u1ecb t\u0103ng acid uric m\u00e1u m\u1ea1n t\u00ednh<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Febuliv 80mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7<a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/To-huong-dan-su-dung-Febuliv-80mg-vnras.pdf\"> t\u1ea1i \u0111\u00e2y.<\/a> Truy c\u1eadp ng\u00e0y 26 th\u00e1ng 10 n\u0103m 2026<\/li>\n<li>Arrigo FG Cicero, Federica Fogacci, Raffaele Ivan Cincione, Giuliano Tocci, Claudio Borghi (2020), Clinical Effects of Xanthine Oxidase Inhibitors in Hyperuricemic Patients. Truy c\u1eadp ng\u00e0y 26 th\u00e1ng 10 n\u0103m 2026 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8114083\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8114083\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Febuliv 80mg ch\u1ee9a febuxostat, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ki\u1ec3m so\u00e1t t\u00ecnh tr\u1ea1ng t\u0103ng acid uric m\u00e1u k\u00e9o d\u00e0i \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh m\u1eafc b\u1ec7nh g\u00fat, gi\u00fap h\u1ea1n ch\u1ebf s\u1ef1 t\u00edch t\u1ee5 urat trong c\u01a1 th\u1ec3<\/p>\n","protected":false},"author":1,"featured_media":164265,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-164157","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/164157","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=164157"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/164265"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=164157"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=164157"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=164157"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}