{"id":164010,"date":"2026-10-19T15:55:31","date_gmt":"2026-10-19T08:55:31","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=164010"},"modified":"2026-10-19T15:56:48","modified_gmt":"2026-10-19T08:56:48","slug":"solamup-60","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/solamup-60\/","title":{"rendered":"Solamup 60"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Solamup 60 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Wealphar c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110375924<\/b><\/p>\n<h2>Thu\u1ed1c Solamup 60 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <b>Solamup 60<\/b> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Dexlansoprazol (d\u01b0\u1edbi d\u1ea1ng pellet dexlansoprazol 20%): 60mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang c\u1ee9ng ch\u1ee9a pellet bao tan trong ru\u1ed9t<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110375924<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Solamup 60<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Qu\u00e1 tr\u00ecnh ti\u1ebft acid t\u1ea1i d\u1ea1 d\u00e0y \u0111\u01b0\u1ee3c dexlansoprazol ki\u1ec3m so\u00e1t th\u00f4ng qua s\u1ef1 \u1ee9c ch\u1ebf enzym H\u207a\/K\u207a-ATPase n\u1eb1m tr\u00ean t\u1ebf b\u00e0o th\u00e0nh. \u0110\u00e2y l\u00e0 enzym \u0111\u1ea3m nhi\u1ec7m kh\u00e2u cu\u1ed1i trong c\u01a1 ch\u1ebf b\u00e0i ti\u1ebft acid d\u1ecbch v\u1ecb. Thu\u1ed9c nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton (PPI), dexlansoprazol l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng acid \u0111\u01b0\u1ee3c gi\u1ea3i ph\u00f3ng v\u00e0o l\u00f2ng d\u1ea1 d\u00e0y b\u1eb1ng c\u00e1ch t\u00e1c \u0111\u1ed9ng l\u00ean h\u1ec7 th\u1ed1ng enzym n\u00e0y.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>\u1ede ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh, khi s\u1eed d\u1ee5ng dexlansoprazol v\u1edbi li\u1ec1u 30 mg ho\u1eb7c 60 mg, c\u1ea3 n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng (Cmax) v\u00e0 t\u1ed5ng m\u1ee9c \u0111\u1ed9 ph\u01a1i nhi\u1ec5m thu\u1ed1c (AUC) \u0111\u1ec1u ghi nh\u1eadn xu h\u01b0\u1edbng t\u0103ng theo li\u1ec1u d\u00f9ng.<\/p>\n<p>\u1ede ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh, t\u1ef7 l\u1ec7 dexlansoprazol li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng n\u1eb1m trong kho\u1ea3ng 96,1-98,8% v\u00e0 kh\u00f4ng thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 khi n\u1ed3ng \u0111\u1ed9 thu\u1ed1c dao \u0111\u1ed9ng t\u1eeb 0,01 \u0111\u1ebfn 20 mcg\/mL. \u1ede b\u1ec7nh nh\u00e2n tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y th\u1ef1c qu\u1ea3n c\u00f3 tri\u1ec7u ch\u1ee9ng, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 bi\u1ec3u ki\u1ebfn (Vz\/F) sau khi d\u00f9ng thu\u1ed1c l\u1eb7p l\u1ea1i \u0111\u01b0\u1ee3c ghi nh\u1eadn \u1edf m\u1ee9c 40,3 l\u00edt.<\/p>\n<p>Dexlansoprazol \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu t\u1ea1i gan qua c\u00e1c ph\u1ea3n \u1ee9ng oxy h\u00f3a, kh\u1eed v\u00e0 li\u00ean h\u1ee3p, t\u1ea1o th\u00e0nh nh\u1eefng ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng c\u00f2n ho\u1ea1t t\u00ednh. Qu\u00e1 tr\u00ecnh n\u00e0y c\u00f3 s\u1ef1 tham gia c\u1ee7a CYP2C19 (ch\u1ee7 y\u1ebfu hydroxyl h\u00f3a) v\u00e0 CYP3A4 (t\u1ea1o dexlansoprazol sulfon). Ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a CYP2C19 trung gian ho\u1eb7c k\u00e9m th\u01b0\u1eddng c\u00f3 m\u1ee9c ph\u01a1i nhi\u1ec5m thu\u1ed1c cao h\u01a1n. \u1ede nh\u00f3m chuy\u1ec3n h\u00f3a m\u1ea1nh v\u00e0 trung gian, 5-hydroxy dexlansoprazol c\u00f9ng d\u1ea1ng li\u00ean h\u1ee3p glucuronid l\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh trong huy\u1ebft t\u01b0\u01a1ng; c\u00f2n \u1edf nh\u00f3m chuy\u1ec3n h\u00f3a k\u00e9m, ch\u1ea5t chuy\u1ec3n h\u00f3a sulfon chi\u1ebfm \u01b0u th\u1ebf.<\/p>\n<p>Dexlansoprazol \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu d\u01b0\u1edbi d\u1ea1ng c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a, kh\u00f4ng t\u00ecm th\u1ea5y thu\u1ed1c nguy\u00ean v\u1eb9n trong n\u01b0\u1edbc ti\u1ec3u. Khi theo d\u00f5i 6 nam t\u00ecnh nguy\u1ec7n vi\u00ean kh\u1ecfe m\u1ea1nh sau khi d\u00f9ng dexlansoprazol g\u1eafn \u0111\u1ed3ng v\u1ecb ph\u00f3ng x\u1ea1 14C, t\u1ef7 l\u1ec7 ho\u1ea1t \u0111\u1ed9 ph\u00f3ng x\u1ea1 \u0111\u01b0\u1ee3c thu h\u1ed3i qua hai \u0111\u01b0\u1eddng th\u1ea3i tr\u1eeb l\u1ea7n l\u01b0\u1ee3t l\u00e0 50,7% qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 47,6% qua ph\u00e2n. Sau 5 ng\u00e0y s\u1eed d\u1ee5ng li\u1ec1u 30 mg ho\u1eb7c 60 mg m\u1ed7i ng\u00e0y, \u0111\u1ed9 thanh th\u1ea3i bi\u1ec3u ki\u1ebfn ghi nh\u1eadn \u1edf m\u1ee9c 11,4-11,6 L\/gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Solamup 60 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb t\u1ed5n th\u01b0\u01a1ng v\u00e0 duy tr\u00ec tr\u1ea1ng th\u00e1i l\u00e0nh ni\u00eam m\u1ea1c \u1edf b\u1ec7nh nh\u00e2n vi\u00eam th\u1ef1c qu\u1ea3n b\u00e0o m\u00f2n<\/p>\n<p>Gi\u1ea3m c\u1ea3m gi\u00e1c \u1ee3 n\u00f3ng \u1edf ng\u01b0\u1eddi b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y &#8211; th\u1ef1c qu\u1ea3n ch\u01b0a xu\u1ea5t hi\u1ec7n t\u1ed5n th\u01b0\u01a1ng th\u1ef1c th\u1ec3<\/p>\n<figure id=\"attachment_164014\" aria-describedby=\"caption-attachment-164014\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-164014\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/Solamup-60.jpg\" alt=\"Thu\u1ed1c Solamup 60\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/Solamup-60.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/Solamup-60-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/Solamup-60-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/Solamup-60-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/Solamup-60-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-164014\" class=\"wp-caption-text\">Thu\u1ed1c Solamup 60 \u0111i\u1ec1u tr\u1ecb vi\u00eam th\u1ef1c qu\u1ea3n do tr\u00e0o ng\u01b0\u1ee3c<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>N\u00ean \u01b0u ti\u00ean s\u1eed d\u1ee5ng PPI \u1edf m\u1ee9c li\u1ec1u th\u1ea5p nh\u1ea5t mang l\u1ea1i hi\u1ec7u qu\u1ea3 v\u00e0 trong th\u1eddi gian ng\u1eafn nh\u1ea5t c\u00f3 th\u1ec3, t\u00f9y thu\u1ed9c v\u00e0o m\u1ee5c \u0111\u00edch \u0111i\u1ec1u tr\u1ecb<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb vi\u00eam th\u1ef1c qu\u1ea3n \u0103n m\u00f2n (cho ngu\u1ecfi t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean): Li\u1ec1u dexlansoprazol \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o l\u00e0 60 mg m\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n, \u00e1p d\u1ee5ng trong th\u1eddi gian kh\u00f4ng qu\u00e1 8 tu\u1ea7n.<\/p>\n<p>Ph\u00f2ng ng\u1eeba t\u00e1i ph\u00e1t sau khi vi\u00eam th\u1ef1c qu\u1ea3n \u0103n m\u00f2n h\u1ed3i ph\u1ee5c (cho ngu\u1ecfi t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean): S\u1eed d\u1ee5ng li\u1ec1u 1 vi\u00ean Solamup 30mg m\u1ed7i ng\u00e0y. V\u1edbi ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed vi\u00eam th\u1ef1c qu\u1ea3n \u0103n m\u00f2n m\u1ee9c \u0111\u1ed9 v\u1eeba ho\u1eb7c n\u1eb7ng, c\u00f3 th\u1ec3 xem x\u00e9t t\u0103ng li\u1ec1u l\u00ean 60 mg\/ng\u00e0y. Th\u1eddi gian duy tr\u00ec kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 6 th\u00e1ng \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh v\u00e0 4 th\u00e1ng \u1edf tr\u1ebb v\u1ecb th\u00e0nh ni\u00ean t\u1eeb 12 \u0111\u1ebfn 17 tu\u1ed5i.<\/p>\n<p>Ki\u1ec3m so\u00e1t tri\u1ec7u ch\u1ee9ng GERD kh\u00f4ng k\u00e8m vi\u00eam th\u1ef1c qu\u1ea3n \u0103n m\u00f2n (cho ngu\u1ecfi t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean): 1 vi\u00ean Solamup 30mg m\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n, li\u1ec7u tr\u00ecnh k\u00e9o d\u00e0i 4 tu\u1ea7n.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i, b\u1ec7nh nh\u00e2n suy th\u1eadn v\u00e0 ng\u01b0\u1eddi suy gan nh\u1eb9 (Child-Pugh A): Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u dexlansoprazol.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan trung b\u00ecnh (Child-Pugh B): C\u00e2n nh\u1eafc s\u1eed d\u1ee5ng vi\u00ean Solamup 30mg.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan n\u1eb7ng (Child-Pugh C) v\u00e0 tr\u1ebb d\u01b0\u1edbi 12 tu\u1ed5i: Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u \u0111\u1ec3 \u0111\u01b0a ra khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng ph\u00f9 h\u1ee3p.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p><b>Vi\u00ean nang Solamup 60<\/b> \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, kh\u00f4ng ph\u1ee5 thu\u1ed9c b\u1eefa \u0103n<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Solamup 60 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi dexlansoprazol ho\u1eb7c t\u00e1 d\u01b0\u1ee3c c\u00f3 trong Solamup 60<\/p>\n<p>D\u00f9ng c\u00f9ng l\u00fac v\u1edbi rilpivirin<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>\u0110\u00e1p \u1ee9ng t\u1ed1t v\u1edbi dexlansoprazol kh\u00f4ng lo\u1ea1i tr\u1eeb kh\u1ea3 n\u0103ng m\u1eafc b\u1ec7nh \u00e1c t\u00ednh. N\u1ebfu ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i ho\u1eb7c xu\u1ea5t hi\u1ec7n sau khi d\u00f9ng kh\u00e1ng sinh, c\u1ea7n l\u01b0u \u00fd nguy c\u01a1 nhi\u1ec5m Clostridioides difficile.<\/p>\n<p>N\u00ean s\u1eed d\u1ee5ng thu\u1ed1c \u1edf li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 hi\u1ec7u qu\u1ea3 trong th\u1eddi gian c\u1ea7n thi\u1ebft. \u0110i\u1ec1u tr\u1ecb k\u00e9o d\u00e0i c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 g\u00e3y x\u01b0\u01a1ng, polyp tuy\u1ebfn \u0111\u00e1y v\u1ecb, h\u1ea1 magnesi m\u00e1u v\u00e0 gi\u1ea3m h\u1ea5p thu vitamin B12. C\u00e2n nh\u1eafc theo d\u00f5i magnesi \u1edf ng\u01b0\u1eddi \u0111i\u1ec1u tr\u1ecb l\u00e2u d\u00e0i ho\u1eb7c d\u00f9ng k\u00e8m digoxin, thu\u1ed1c l\u1ee3i ti\u1ec3u.<\/p>\n<p>Ph\u1ed1i h\u1ee3p v\u1edbi methotrexat li\u1ec1u cao c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 thu\u1ed1c v\u00e0 nguy c\u01a1 \u0111\u1ed9c t\u00ednh; c\u00e2n nh\u1eafc t\u1ea1m ng\u1eebng dexlansoprazol theo ch\u1ec9 \u0111\u1ecbnh chuy\u00ean m\u00f4n.<\/p>\n<p>Kh\u00f4ng d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi rilpivirin; tr\u00e1nh ph\u1ed1i h\u1ee3p v\u1edbi atazanavir ho\u1eb7c nelfinavir do nguy c\u01a1 gi\u1ea3m hi\u1ec7u qu\u1ea3 kh\u00e1ng virus. N\u1ebfu d\u00f9ng c\u00f9ng saquinavir, c\u1ea7n theo d\u00f5i \u0111\u1ed9c t\u00ednh v\u00e0 c\u00e2n nh\u1eafc \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/p>\n<p>Dexlansoprazol c\u00f3 th\u1ec3 l\u00e0m t\u0103ng Chromogranin A, g\u00e2y sai l\u1ec7ch k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m. C\u1ea7n ng\u1eebng thu\u1ed1c 14 ng\u00e0y tr\u01b0\u1edbc khi x\u00e9t nghi\u1ec7m theo h\u01b0\u1edbng d\u1eabn c\u1ee7a nh\u00e2n vi\u00ean y t\u1ebf.<\/p>\n<p>N\u1ebfu xu\u1ea5t hi\u1ec7n t\u1ed5n th\u01b0\u01a1ng da nghi ng\u1edd lupus ban \u0111\u1ecf b\u00e1n c\u1ea5p, \u0111\u1eb7c bi\u1ec7t khi k\u00e8m \u0111au kh\u1edbp ho\u1eb7c xu\u1ea5t hi\u1ec7n \u1edf v\u00f9ng da ti\u1ebfp x\u00fac \u00e1nh n\u1eafng, c\u1ea7n \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 v\u00e0 c\u00e2n nh\u1eafc ng\u1eebng thu\u1ed1c.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>C\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o sau khi l\u01b0u h\u00e0nh dexlansoprazol bao g\u1ed3m h\u1ea1 natri m\u00e1u, vi\u00eam t\u1ee5y, h\u1ed9i ch\u1ee9ng DRESS, \u0111i\u1ebfc, lo\u00e3ng x\u01b0\u01a1ng v\u00e0 g\u00e3y x\u01b0\u01a1ng li\u00ean quan, s\u1ed1c ph\u1ea3n v\u1ec7, polyp tuy\u1ebfn \u0111\u00e1y v\u1ecb, thi\u1ebfu m\u00e1u tan m\u00e1u t\u1ef1 mi\u1ec5n, ph\u00e1t ban to\u00e0n th\u00e2n, h\u1ea1 magnesi m\u00e1u, vi\u00eam gan do thu\u1ed1c, tai bi\u1ebfn m\u1ea1ch m\u00e1u n\u00e3o, ph\u00f9 m\u1eb7t, h\u1ed9i ch\u1ee9ng Stevens-Johnson, h\u1ea1 kali m\u00e1u, vi\u00eam m\u1ea1ch b\u1ea1ch c\u1ea7u, ban xu\u1ea5t huy\u1ebft gi\u1ea3m ti\u1ec3u c\u1ea7u v\u00f4 c\u0103n, suy th\u1eadn c\u1ea5p, lupus ban \u0111\u1ecf b\u00e1n c\u1ea5p \u1edf da, h\u1ea1 calci huy\u1ebft, ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c, c\u01a1n thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 tho\u00e1ng qua, vi\u00eam da tr\u00f3c v\u1ea3y, ph\u1ee7 mi\u1ec7ng, m\u1edf m\u1eaft, ph\u00f9 h\u1ea7u h\u1ecdng v\u00e0 th\u1eaft c\u1ed5 h\u1ecdng.<\/p>\n<p>Ng\u1eebng thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton sau th\u1eddi gian \u0111i\u1ec1u tr\u1ecb k\u00e9o d\u00e0i c\u00f3 th\u1ec3 l\u00e0m tri\u1ec7u ch\u1ee9ng li\u00ean quan \u0111\u1ebfn acid n\u1eb7ng h\u01a1n do t\u0103ng ti\u1ebft acid h\u1ed3i \u1ee9ng.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Dexlansoprazol c\u00f3 th\u1ec3 l\u00e0m thay \u0111\u1ed5i qu\u00e1 tr\u00ecnh h\u1ea5p thu c\u1ee7a m\u1ed9t s\u1ed1 thu\u1ed1c nh\u01b0 ampicillin este, digoxin, mu\u1ed1i s\u1eaft v\u00e0 ketoconazol do kh\u1ea3 n\u0103ng h\u1ea5p thu c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y ch\u1ecbu \u1ea3nh h\u01b0\u1edfng b\u1edfi \u0111\u1ed9 pH trong d\u1ea1 d\u00e0y.<\/p>\n<p>Dexlansoprazol \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a nh\u1edd c\u00e1c enzym CYP2C19 v\u00e0 CYP3A4. D\u1eef li\u1ec7u nghi\u00ean c\u1ee9u hi\u1ec7n c\u00f3 ch\u01b0a cho th\u1ea5y t\u01b0\u01a1ng t\u00e1c \u0111\u00e1ng k\u1ec3 v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng gi\u1eefa thu\u1ed1c v\u1edbi phenytoin, theophyllin ho\u1eb7c diazepam.<\/p>\n<p>Khi s\u1eed d\u1ee5ng c\u00f9ng warfarin, ch\u01b0a ghi nh\u1eadn bi\u1ebfn \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 v\u1ec1 d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a warfarin hay ch\u1ec9 s\u1ed1 INR trong nghi\u00ean c\u1ee9u ph\u1ed1i h\u1ee3p. Tuy nhi\u00ean, v\u1eabn c\u1ea7n ki\u1ec3m tra INR v\u00e0 th\u1eddi gian prothrombin \u0111\u1ecbnh k\u1ef3 \u0111\u1ec3 ph\u00e1t hi\u1ec7n nguy c\u01a1 r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u.<\/p>\n<p>C\u00e1c thu\u1ed1c kh\u00e1ng acid c\u00f3 ch\u1ee9a nh\u00f4m ho\u1eb7c magnesi \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u1ee7a lansoprazol trong huy\u1ebft t\u01b0\u01a1ng nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn sinh kh\u1ea3 d\u1ee5ng. C\u00f3 th\u1ec3 d\u00f9ng thu\u1ed1c kh\u00e1ng acid c\u00f9ng dexlansoprazol khi c\u1ea7n thi\u1ebft.<\/p>\n<p>Sucralfat c\u00f3 th\u1ec3 khi\u1ebfn qu\u00e1 tr\u00ecnh h\u1ea5p thu thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton di\u1ec5n ra ch\u1eadm h\u01a1n, \u0111\u1ed3ng th\u1eddi l\u00e0m gi\u1ea3m m\u1ee9c \u0111\u1ed9 ph\u01a1i nhi\u1ec5m thu\u1ed1c. D\u1ef1a tr\u00ean d\u1eef li\u1ec7u c\u1ee7a lansoprazol, n\u00ean u\u1ed1ng dexlansoprazol tr\u01b0\u1edbc sucralfat \u00edt nh\u1ea5t 30 ph\u00fat.<\/p>\n<p>M\u1eb7c d\u00f9 ch\u01b0a ph\u00e1t hi\u1ec7n \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 c\u1ee7a dexlansoprazol \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc v\u00e0 d\u01b0\u1ee3c l\u1ef1c h\u1ecdc c\u1ee7a theophyllin, vi\u1ec7c theo d\u00f5i n\u1ed3ng \u0111\u1ed9 theophyllin v\u1eabn c\u1ea7n \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc khi hai thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi.<\/p>\n<p>\u1ede ng\u01b0\u1eddi d\u00f9ng tacrolimus, ph\u1ed1i h\u1ee3p v\u1edbi dexlansoprazol c\u00f3 th\u1ec3 khi\u1ebfn n\u1ed3ng \u0111\u1ed9 tacrolimus trong m\u00e1u t\u0103ng l\u00ean. Nguy c\u01a1 n\u00e0y c\u1ea7n \u0111\u01b0\u1ee3c l\u01b0u \u00fd nhi\u1ec1u h\u01a1n \u1edf b\u1ec7nh nh\u00e2n gh\u00e9p t\u1ea1ng v\u00e0 nh\u1eefng ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a thu\u1ed1c qua CYP2C19 \u1edf m\u1ee9c trung gian ho\u1eb7c k\u00e9m.<\/p>\n<p>C\u00e1c nghi\u00ean c\u1ee9u tr\u00ean ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh cho th\u1ea5y dexlansoprazol kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh c\u1ee7a clopidogrel ho\u1eb7c kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u c\u1ee7a thu\u1ed1c. V\u00ec v\u1eady, kh\u00f4ng c\u1ea7n thay \u0111\u1ed5i li\u1ec1u clopidogrel khi s\u1eed d\u1ee5ng c\u00f9ng dexlansoprazol \u1edf li\u1ec1u khuy\u1ebfn c\u00e1o.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 methotrexat trong huy\u1ebft thanh v\u00e0 th\u1eddi gian thu\u1ed1c t\u1ed3n t\u1ea1i trong c\u01a1 th\u1ec3 c\u00f3 th\u1ec3 t\u0103ng khi d\u00f9ng chung v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton, \u0111\u1eb7c bi\u1ec7t trong tr\u01b0\u1eddng h\u1ee3p \u0111i\u1ec1u tr\u1ecb b\u1eb1ng methotrexat li\u1ec1u cao.<\/p>\n<p>Dexlansoprazol kh\u00f4ng n\u00ean d\u00f9ng c\u00f9ng rilpivirin v\u00ec c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 m\u1ee9c ph\u01a1i nhi\u1ec5m rilpivirin, t\u1eeb \u0111\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>S\u1ef1 h\u1ea5p thu atazanavir c\u00f3 th\u1ec3 suy gi\u1ea3m \u0111\u00e1ng k\u1ec3 khi ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c l\u00e0m gi\u1ea3m ti\u1ebft acid d\u1ea1 d\u00e0y. Do \u0111\u00f3, c\u1ea7n tr\u00e1nh s\u1eed d\u1ee5ng atazanavir \u0111\u1ed3ng th\u1eddi v\u1edbi dexlansoprazol.<\/p>\n<p>Ph\u1ed1i h\u1ee3p dexlansoprazol v\u1edbi nelfinavir kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o v\u00ec c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 nelfinavir v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh, g\u00e2y nguy c\u01a1 gi\u1ea3m hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Khi d\u00f9ng c\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf ti\u1ebft acid, saquinavir c\u00f3 th\u1ec3 t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng xu\u1ea5t hi\u1ec7n \u0111\u1ed9c t\u00ednh. Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i c\u1ea9n th\u1eadn, \u0111\u1ed3ng th\u1eddi c\u00e2n nh\u1eafc \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u saquinavir theo ch\u1ec9 \u0111\u1ecbnh chuy\u00ean m\u00f4n.<\/p>\n<p>Trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb b\u1eb1ng dexlansoprazol, n\u1ed3ng \u0111\u1ed9 Chromogranin A (CgA) c\u00f3 th\u1ec3 t\u0103ng do s\u1ef1 \u1ee9c ch\u1ebf b\u00e0i ti\u1ebft acid d\u1ea1 d\u00e0y. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 g\u00e2y sai l\u1ec7ch k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m ph\u1ee5c v\u1ee5 ch\u1ea9n \u0111o\u00e1n kh\u1ed1i u th\u1ea7n kinh n\u1ed9i ti\u1ebft. Theo t\u00e0i li\u1ec7u ngu\u1ed3n, c\u1ea7n ng\u1eebng thu\u1ed1c 14 ng\u00e0y tr\u01b0\u1edbc khi x\u00e9t nghi\u1ec7m, d\u01b0\u1edbi s\u1ef1 h\u01b0\u1edbng d\u1eabn c\u1ee7a nh\u00e2n vi\u00ean y t\u1ebf.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Hi\u1ec7n ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u l\u00e2m s\u00e0ng \u0111\u00e1ng tin c\u1eady \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 m\u1ee9c \u0111\u1ed9 an to\u00e0n c\u1ee7a dexlansoprazol trong thai k\u1ef3. Do kinh nghi\u1ec7m s\u1eed d\u1ee5ng thu\u1ed1c tr\u00ean \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y c\u00f2n h\u1ea1n ch\u1ebf, ch\u1ec9 n\u00ean d\u00f9ng khi c\u00e2n nh\u1eafc l\u1ee3i \u00edch nguy c\u01a1 c\u1ea9n th\u1eadn<\/p>\n<p>Kh\u1ea3 n\u0103ng ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 c\u1ee7a Dexlansoprazole ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh r\u00f5 r\u00e0ng tr\u00ean l\u00e2m s\u00e0ng. D\u00f9 v\u1eady, Lansoprazole c\u00f9ng c\u00e1c d\u1eabn ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn xu\u1ea5t hi\u1ec7n trong s\u1eefa \u1edf \u0111\u1ed9ng v\u1eadt th\u00ed nghi\u1ec7m (chu\u1ed9t). Do ph\u1ea7n l\u1edbn d\u01b0\u1ee3c ch\u1ea5t \u0111\u1ec1u c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9, n\u00ean h\u1ea1n ch\u1ebf ch\u1ec9 \u0111\u1ecbnh Dexlansoprazole trong th\u1eddi k\u1ef3 nu\u00f4i con b\u1eb1ng s\u1eefa m\u1eb9, ngo\u1ea1i tr\u1eeb tr\u01b0\u1eddng h\u1ee3p th\u1eadt s\u1ef1 c\u1ea5p thi\u1ebft, ho\u1eb7c n\u1ebfu c\u1ea7n c\u00f3 th\u1ec3 ng\u1eebng cho con b\u00fa<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>V\u00ec ch\u01b0a c\u00f3 th\u00f4ng tin v\u00e0 c\u00e1ch x\u1eed tr\u00ed c\u1ee5 th\u1ec3 n\u00e0o n\u00ean ch\u1ee7 y\u1ebfu x\u1eed l\u00fd b\u1eb1ng c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 v\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng t\u00f9y theo t\u00ecnh tr\u1ea1ng b\u1ec7nh nh\u00e2n<\/p>\n<p>L\u1ecdc m\u00e1u nh\u00e2n t\u1ea1o (th\u1ea9m t\u00e1ch m\u00e1u) d\u1ef1 ki\u1ebfn kh\u00f4ng mang l\u1ea1i hi\u1ec7u qu\u1ea3 trong vi\u1ec7c \u0111\u00e0o th\u1ea3i Dexlansoprazole kh\u1ecfi tu\u1ea7n ho\u00e0n c\u01a1 th\u1ec3.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Solamup 60 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Solamup 60 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Solamup 60 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>Solamup 60 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Solamup 60 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Solamup 60 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Solamup 60 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Solamup 60 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/dexilant\/\">Dexilant 60mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Dexlansoprazole 60mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Takeda Pharmaceuticals, \u0111i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/miklanso-30mg\/\">Miklanso 30mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Dexlansoprazole 30mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c v\u1eadt t\u01b0 y t\u1ebf H\u1ea3i D\u01b0\u01a1ng, \u0111i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Solamup 60 \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/To-huong-dan-su-dung-Solamup-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 19 th\u00e1ng 10 n\u0103m 2026<\/li>\n<li>Skrzyd\u0142o-Radoma\u0144ska B, Radwan P (2015). Dexlansoprazole &#8211; a new-generation proton pump inhibitor. Prz Gastroenterol. Truy c\u1eadp ng\u00e0y 19 th\u00e1ng 10 n\u0103m 2026 t\u1eeb:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26759624\/\" rel=\"noopener\"> https:\/\/pubmed.ncbi.nlm.nih.gov\/26759624\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Solamup 60 ch\u1ee9a ho\u1ea1t ch\u1ea5t dexlansoprazol h\u00e0m l\u01b0\u1ee3ng 60mg, gi\u00fap \u0111i\u1ec1u tr\u1ecb vi\u00eam th\u1ef1c qu\u1ea3n \u0103n m\u00f2n v\u00e0 gi\u1ea3m tri\u1ec7u ch\u1ee9ng \u1ee3 n\u00f3ng do tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n.<\/p>\n","protected":false},"author":1,"featured_media":164016,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-164010","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/164010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=164010"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/164016"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=164010"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=164010"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=164010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}