{"id":163621,"date":"2026-10-08T15:40:35","date_gmt":"2026-10-08T08:40:35","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=163621"},"modified":"2026-10-08T15:44:04","modified_gmt":"2026-10-08T08:44:04","slug":"thuoc-cozaar-xq-5-50mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-cozaar-xq-5-50mg\/","title":{"rendered":"Cozaar XQ 5\/50mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Cozaar XQ 5\/50mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Hanmi Pharm.Co., Ltd,(Paltan site) c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-17524-13<\/b><\/p>\n<h2>Cozaar XQ 5\/50mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i vi\u00ean\u00a0<b>Cozaar XQ 5\/50mg<\/b> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Amlodipine (d\u01b0\u1edbi d\u1ea1ng Amlodipine camsylate): 5mg<\/li>\n<li>Losartan kali: 50mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-17524-13<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: H\u00e0n Qu\u1ed1c<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Cozaar XQ 5\/50mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Cozaar XQ ch\u1ee9a hai ho\u1ea1t ch\u1ea5t c\u00f3 c\u01a1 ch\u1ebf h\u1ea1 huy\u1ebft \u00e1p kh\u00e1c nhau l\u00e0 losartan v\u00e0 amlodipine. T\u00e1c d\u1ee5ng chung c\u1ee7a thu\u1ed1c l\u00e0 l\u00e0m gi\u00e3n m\u1ea1ch, qua \u0111\u00f3 gi\u1ea3m s\u1ee9c c\u1ea3n m\u1ea1ch ngo\u1ea1i vi v\u00e0 \u0111\u01b0a huy\u1ebft \u00e1p xu\u1ed1ng.<\/p>\n<p>Losartan t\u00e1c \u0111\u1ed9ng l\u00ean h\u1ec7 renin-angiotensin b\u1eb1ng c\u00e1ch ng\u0103n angiotensin II ho\u1ea1t h\u00f3a th\u1ee5 th\u1ec3 AT1. Nh\u1edd s\u1ef1 \u1ee9c ch\u1ebf n\u00e0y, c\u00e1c t\u00e1c \u0111\u1ed9ng g\u00e2y co m\u1ea1ch c\u1ee7a angiotensin II b\u1ecb h\u1ea1n ch\u1ebf, \u0111\u1ed3ng th\u1eddi gi\u1ea3m nh\u1eefng \u1ea3nh h\u01b0\u1edfng c\u1ee7a h\u1ec7 n\u00e0y l\u00ean huy\u1ebft \u00e1p. Losartan kh\u00f4ng \u1ee9c ch\u1ebf enzym chuy\u1ec3n angiotensin (ACE), do \u0111\u00f3 kh\u00f4ng c\u1ea3n tr\u1edf qu\u00e1 tr\u00ecnh ph\u00e2n h\u1ee7y bradykinin. C\u1ea3 losartan v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f2n ho\u1ea1t t\u00ednh c\u1ee7a thu\u1ed1c \u0111\u1ec1u c\u00f3 kh\u1ea3 n\u0103ng \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 AT1 v\u00e0 c\u00f9ng tham gia v\u00e0o t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<p>Amlodipine thu\u1ed9c nh\u00f3m ch\u1eb9n k\u00eanh calci. Thu\u1ed1c l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng calci \u0111i v\u00e0o t\u1ebf b\u00e0o c\u01a1 tr\u01a1n c\u1ee7a th\u00e0nh m\u1ea1ch, khi\u1ebfn c\u00e1c m\u1ea1ch m\u00e1u gi\u00e3n ra v\u00e0 s\u1ee9c c\u1ea3n ngo\u1ea1i vi gi\u1ea3m. S\u1ef1 ph\u1ed1i h\u1ee3p gi\u1eefa t\u00e1c \u0111\u1ed9ng \u0111\u1ed1i kh\u00e1ng angiotensin II c\u1ee7a losartan v\u00e0 t\u00e1c d\u1ee5ng gi\u00e3n m\u1ea1ch c\u1ee7a amlodipine gi\u00fap t\u0103ng c\u01b0\u1eddng hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<h4>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a losartan<\/h4>\n<p>H\u1ea5p thu: Sau khi d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, losartan \u0111\u01b0\u1ee3c h\u1ea5p thu v\u00e0 nhanh ch\u00f3ng tr\u1ea3i qua qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a l\u1ea7n \u0111\u1ea7u \u1edf gan, v\u1edbi sinh kh\u1ea3 d\u1ee5ng to\u00e0n th\u00e2n kho\u1ea3ng 33%. Th\u1eddi \u0111i\u1ec3m \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 cao nh\u1ea5t trong huy\u1ebft t\u01b0\u01a1ng v\u00e0o kho\u1ea3ng 1 gi\u1edd \u0111\u1ed1i v\u1edbi losartan v\u00e0 3-4 gi\u1edd \u0111\u1ed1i v\u1edbi ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh EXP3174. Vi\u1ec7c d\u00f9ng thu\u1ed1c c\u00f9ng th\u1ee9c \u0103n kh\u00f4ng l\u00e0m thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 losartan trong huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<p>Ph\u00e2n b\u1ed1: Losartan v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a EXP3174 c\u00f3 m\u1ee9c \u0111\u1ed9 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng r\u1ea5t cao, tr\u00ean 99%, ch\u1ee7 y\u1ebfu l\u00e0 albumin. Thu\u1ed1c c\u00f3 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 34 L v\u00e0 ch\u1ec9 \u0111i qua h\u00e0ng r\u00e0o m\u00e1u-n\u00e3o v\u1edbi m\u1ee9c \u0111\u1ed9 r\u1ea5t h\u1ea1n ch\u1ebf..<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Kho\u1ea3ng 14% l\u01b0\u1ee3ng losartan \u0111\u01b0a v\u00e0o c\u01a1 th\u1ec3 \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh EXP3174, l\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a v\u1eabn c\u00f2n ho\u1ea1t t\u00ednh. B\u00ean c\u1ea1nh \u0111\u00f3, losartan c\u00f2n tr\u1ea3i qua c\u00e1c qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a kh\u00e1c \u0111\u1ec3 t\u1ea1o th\u00e0nh nh\u1eefng ch\u1ea5t kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh, ch\u1ee7 y\u1ebfu li\u00ean quan \u0111\u1ebfn hydroxyl h\u00f3a m\u1ea1ch b\u00ean butyl v\u00e0 t\u1ea1o glucuronid. Ch\u1ec9 kho\u1ea3ng 1% ng\u01b0\u1eddi d\u00f9ng c\u00f3 kh\u1ea3 n\u0103ng chuy\u1ec3n losartan th\u00e0nh EXP3174 \u1edf m\u1ee9c th\u1ea5p.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Losartan c\u00f9ng ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c lo\u1ea1i kh\u1ecfi c\u01a1 th\u1ec3 b\u1eb1ng c\u1ea3 n\u01b0\u1edbc ti\u1ec3u v\u00e0 \u0111\u01b0\u1eddng m\u1eadt. V\u1edbi \u0111\u01b0\u1eddng u\u1ed1ng, kho\u1ea3ng 4% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong n\u01b0\u1edbc ti\u1ec3u \u1edf d\u1ea1ng losartan nguy\u00ean v\u1eb9n, trong khi kho\u1ea3ng 6% \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i d\u01b0\u1edbi d\u1ea1ng EXP3174. Th\u1eddi gian b\u00e1n th\u1ea3i cu\u1ed1i l\u1ea7n l\u01b0\u1ee3t kho\u1ea3ng 2 gi\u1edd \u0111\u1ed1i v\u1edbi losartan v\u00e0 6-9 gi\u1edd \u0111\u1ed1i v\u1edbi EXP3174. Khi s\u1eed d\u1ee5ng li\u1ec1u 100 mg m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y, l\u01b0\u1ee3ng thu\u1ed1c v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a trong huy\u1ebft t\u01b0\u01a1ng kh\u00f4ng t\u00edch l\u0169y \u0111\u00e1ng k\u1ec3. Trong ph\u1ea1m vi li\u1ec1u u\u1ed1ng \u0111\u1ebfn 200 mg, m\u1ee9c ph\u01a1i nhi\u1ec5m c\u1ee7a losartan v\u00e0 EXP3174 t\u0103ng t\u01b0\u01a1ng \u1ee9ng v\u1edbi li\u1ec1u d\u00f9ng.<\/p>\n<h4>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a amlodipine<\/h4>\n<p>H\u1ea5p thu: Sau khi u\u1ed1ng, amlodipine \u0111\u01b0\u1ee3c h\u1ea5p thu v\u1edbi sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 64-90%. N\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong huy\u1ebft t\u01b0\u01a1ng th\u01b0\u1eddng \u0111\u1ea1t m\u1ee9c cao nh\u1ea5t sau kho\u1ea3ng 6-12 gi\u1edd. Th\u1ee9c \u0103n kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn m\u1ee9c \u0111\u1ed9 h\u1ea5p thu c\u1ee7a amlodipine.<\/p>\n<p>Ph\u00e2n b\u1ed1: \u1ede ng\u01b0\u1eddi b\u1ec7nh t\u0103ng huy\u1ebft \u00e1p, kho\u1ea3ng 93% amlodipine trong tu\u1ea7n ho\u00e0n li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, cho th\u1ea5y thu\u1ed1c c\u00f3 m\u1ee9c \u0111\u1ed9 g\u1eafn protein t\u01b0\u01a1ng \u0111\u1ed1i cao.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Amlodipine chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan, t\u1ea1o ra c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng c\u00f2n ho\u1ea1t t\u00ednh v\u1edbi t\u1ef7 l\u1ec7 kho\u1ea3ng 90%. Qua \u0111\u01b0\u1eddng n\u01b0\u1edbc ti\u1ec3u, kho\u1ea3ng 10% thu\u1ed1c \u1edf d\u1ea1ng ch\u01b0a chuy\u1ec3n h\u00f3a v\u00e0 60% c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ra ngo\u00e0i.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Amlodipine gi\u1ea3m n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft thanh theo m\u00f4 h\u00ecnh hai pha, v\u1edbi th\u1eddi gian b\u00e1n th\u1ea3i \u1edf pha cu\u1ed1i kho\u1ea3ng 30-50 gi\u1edd. \u0110\u1eb7c t\u00ednh n\u00e0y gi\u00fap thu\u1ed1c duy tr\u00ec n\u1ed3ng \u0111\u1ed9 t\u01b0\u01a1ng \u0111\u1ed1i \u1ed5n \u0111\u1ecbnh khi s\u1eed d\u1ee5ng m\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n. N\u1ed3ng \u0111\u1ed9 \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh th\u01b0\u1eddng \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp sau kho\u1ea3ng 7-8 ng\u00e0y \u0111i\u1ec1u tr\u1ecb li\u00ean t\u1ee5c.<\/p>\n<h2>Thu\u1ed1c Cozaar XQ 5\/50mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>D\u00f9ng cho ng\u01b0\u1eddi l\u1edbn t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n trong tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng \u0111\u00e1p \u1ee9ng t\u1ed1t v\u1edbi li\u1ec7u ph\u00e1p \u0111\u01a1n tr\u1ecb b\u1eb1ng m\u1ed9t trong hai th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c l\u00e0 losartan kali v\u00e0 amlodipine camsylate.<\/p>\n<figure id=\"attachment_163631\" aria-describedby=\"caption-attachment-163631\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-163631\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/cozaar-xq-5-50mg-2.jpg\" alt=\"Cozaar XQ 5\/50mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/cozaar-xq-5-50mg-2.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/cozaar-xq-5-50mg-2-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/cozaar-xq-5-50mg-2-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/cozaar-xq-5-50mg-2-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/10\/cozaar-xq-5-50mg-2-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-163631\" class=\"wp-caption-text\">Thu\u1ed1c Cozaar XQ 5\/50mg \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p \u1edf ng\u01b0\u1eddi l\u1edbn<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>1 vi\u00ean\/ng\u00e0y<\/p>\n<p>Tr\u1ebb em do kh\u00f4ng \u0111\u1ee7 d\u1eef li\u1ec7u v\u1ec1 t\u0129nh an to\u00e0n khi d\u00f9ng \u0111\u1ed3ng th\u1eddi 2 ho\u1ea1t ch\u1ea5t n\u00e0y n\u00ean kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng, nh\u1eefng tr\u01b0\u1eddng h\u1ee3p \u0111\u1eb7c bi\u1ec7t \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh theo b\u00e1c s\u0129<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p><strong>Vi\u00ean n\u00e9n Cozaar XQ 5\/50mg<\/strong> \u0111\u01b0\u1ee3c d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng b\u1eefa \u0103n b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Cozaar XQ 5\/50mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi amlodipine camsylate v\u00e0 losartan kali, t\u00e1 d\u01b0\u1ee3c c\u00f3 trong Cozaar XQ c\u00e1c h\u1ee3p ch\u1ea5t thu\u1ed9c nh\u00f3m dihydropyridine.<\/p>\n<p>Thai ph\u1ee5 ho\u1eb7c \u0111ang nghi c\u00f3 thai<\/p>\n<p>Ng\u01b0\u1eddi \u0111ang r\u01a1i v\u00e0o t\u00ecnh tr\u1ea1ng s\u1ed1c<\/p>\n<p>Ng\u01b0\u1eddi b\u1ec7nh g\u1eb7p t\u00ecnh tr\u1ea1ng h\u1eb9p van \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 nghi\u00eam tr\u1ecdng.<\/p>\n<p>Suy gan n\u1eb7ng<\/p>\n<p>\u0110ang cho con b\u00fa<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb, c\u1ea7n l\u01b0u \u00fd t\u00ecnh tr\u1ea1ng gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n, th\u01b0\u1eddng g\u1eb7p \u1edf ng\u01b0\u1eddi \u0111ang s\u1eed d\u1ee5ng thu\u1ed1c l\u1ee3i ti\u1ec3u ho\u1eb7c \u0103n r\u1ea5t \u00edt mu\u1ed1i. C\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh t\u00ecnh tr\u1ea1ng n\u00e0y ho\u1eb7c l\u1ef1a ch\u1ecdn li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u1ea5p h\u01a1n.<\/p>\n<p>Ng\u01b0\u1eddi c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin d\u01b0\u1edbi 20 mL\/ph\u00fat ho\u1eb7c \u0111ang ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i c\u1ea9n th\u1eadn trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng Cozaar XQ.<\/p>\n<p>T\u0103ng kali huy\u1ebft c\u00f3 th\u1ec3 x\u1ea3y ra, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn ho\u1eb7c c\u00f3 c\u00e1c r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a \u0111i k\u00e8m. N\u00ean ki\u1ec3m tra kali m\u00e1u \u0111\u1ecbnh k\u1ef3 \u1edf nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng c\u00f3 nguy c\u01a1.<\/p>\n<p>T\u00ecnh tr\u1ea1ng h\u1ea1 huy\u1ebft \u00e1p bi\u1ec3u hi\u1ec7n b\u1eb1ng tri\u1ec7u ch\u1ee9ng c\u00f3 th\u1ec3 g\u1eb7p \u1edf ng\u01b0\u1eddi gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n ho\u1eb7c h\u1eb9p van \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 n\u1eb7ng. T\u00e1c d\u1ee5ng h\u1ea1 \u00e1p c\u1ee7a thu\u1ed1c xu\u1ea5t hi\u1ec7n t\u01b0\u01a1ng \u0111\u1ed1i t\u1eeb t\u1eeb n\u00ean nguy c\u01a1 n\u00e0y th\u01b0\u1eddng kh\u00f4ng cao.<\/p>\n<p>Ch\u1ee9c n\u0103ng gan c\u1ea7n \u0111\u01b0\u1ee3c l\u01b0u \u00fd khi l\u1ef1a ch\u1ecdn li\u1ec1u. Losartan c\u00f3 th\u1ec3 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 cao h\u01a1n \u1edf ng\u01b0\u1eddi b\u1ecb x\u01a1 gan, trong khi amlodipine c\u00f3 th\u1eddi gian th\u1ea3i tr\u1eeb k\u00e9o d\u00e0i \u0111\u00e1ng k\u1ec3 \u1edf b\u1ec7nh nh\u00e2n suy gan n\u1eb7ng. Vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u amlodipine \u1edf nh\u00f3m n\u00e0y n\u00ean ti\u1ebfn h\u00e0nh t\u1eebng b\u01b0\u1edbc.<\/p>\n<p>Ph\u1ea3n \u1ee9ng ph\u00f9 m\u1ea1ch \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn v\u1edbi losartan. Khi xu\u1ea5t hi\u1ec7n d\u1ea5u hi\u1ec7u ph\u00f9 m\u1ea1ch ho\u1eb7c ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn nghi\u00eam tr\u1ecdng, c\u1ea7n ng\u1eebng thu\u1ed1c v\u00e0 x\u1eed tr\u00ed th\u00edch h\u1ee3p.<\/p>\n<p>R\u1ed1i lo\u1ea1n n\u01b0\u1edbc v\u00e0 \u0111i\u1ec7n gi\u1ea3i c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n \u1edf ng\u01b0\u1eddi suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn, k\u1ec3 c\u1ea3 tr\u01b0\u1eddng h\u1ee3p c\u00f3 ho\u1eb7c kh\u00f4ng k\u00e8m \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng. T\u0103ng kali m\u00e1u c\u1ea7n \u0111\u01b0\u1ee3c \u0111\u1eb7c bi\u1ec7t ch\u00fa \u00fd trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Losartan c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ee9c n\u0103ng th\u1eadn \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n nh\u1ea1y c\u1ea3m do t\u00e1c \u0111\u1ed9ng l\u00ean h\u1ec7 renin-angiotensin. Nguy c\u01a1 n\u00e0y \u0111\u00e1ng l\u01b0u \u00fd \u1edf ng\u01b0\u1eddi h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn hai b\u00ean ho\u1eb7c h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn c\u1ee7a th\u1eadn duy nh\u1ea5t; ch\u1ee9c n\u0103ng th\u1eadn th\u01b0\u1eddng c\u1ea3i thi\u1ec7n sau khi ng\u1eebng thu\u1ed1c.<\/p>\n<p>Ng\u01b0\u1eddi m\u1eafc b\u1ec7nh \u0111\u1ed9ng m\u1ea1ch v\u00e0nh t\u1eafc ngh\u1ebdn n\u1eb7ng c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i khi b\u1eaft \u0111\u1ea7u ho\u1eb7c t\u0103ng li\u1ec1u amlodipine, v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m xu\u1ea5t hi\u1ec7n ho\u1eb7c l\u00e0m n\u1eb7ng th\u00eam c\u01a1n \u0111au th\u1eaft ng\u1ef1c v\u00e0 trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p c\u00f3 th\u1ec3 x\u1ea3y ra nh\u1ed3i m\u00e1u c\u01a1 tim.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p (\u22651\/100, &lt;1\/10): Cho\u00e1ng v\u00e1ng, nh\u1ee9c \u0111\u1ea7u.<\/p>\n<p>\u00cdt g\u1eb7p (\u22651\/1.000, &lt;1\/100): Bu\u1ed3n n\u00f4n, kh\u00f3 ti\u00eau, b\u1ee5ng kh\u00f3 ch\u1ecbu, vi\u00eam th\u1ef1c qu\u1ea3n tr\u00e0o ng\u01b0\u1ee3c, ph\u00f9 \u1ea5n l\u00f5m, ph\u00f9 ngo\u1ea1i bi\u00ean, suy nh\u01b0\u1ee3c, \u0111au ng\u1ef1c, kh\u00f3 ch\u1ecbu \u1edf ng\u1ef1c, bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, kh\u00f3 th\u1edf, \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, \u0111\u1ecf b\u1eebng, h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf \u0111\u1ee9ng, ng\u1ee9a to\u00e0n th\u00e2n, m\u00e0y \u0111ay to\u00e0n th\u00e2n, \u0111\u00e1i r\u1eaft.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Ph\u1ed1i h\u1ee3p losartan v\u1edbi c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali nh\u01b0 spironolacton, triamteren, amilorid, c\u00f9ng ch\u1ebf ph\u1ea9m b\u1ed5 sung kali ho\u1eb7c mu\u1ed1i thay th\u1ebf c\u00f3 ch\u1ee9a kali c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 kali trong m\u00e1u.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 lithium huy\u1ebft thanh c\u00f3 th\u1ec3 t\u0103ng do losartan l\u00e0m gi\u1ea3m th\u1ea3i tr\u1eeb lithium. V\u00ec v\u1eady, c\u1ea7n theo d\u00f5i n\u1ed3ng \u0111\u1ed9 lithium khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi.<\/p>\n<p>C\u00e1c NSAID, bao g\u1ed3m c\u1ea3 thu\u1ed1c \u1ee9c ch\u1ebf COX-2 ch\u1ecdn l\u1ecdc, c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a losartan. S\u1ef1 ph\u1ed1i h\u1ee3p n\u00e0y c\u0169ng c\u00f3 nguy c\u01a1 l\u00e0m suy gi\u1ea3m th\u00eam ch\u1ee9c n\u0103ng th\u1eadn, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi cao tu\u1ed5i, gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n ho\u1eb7c \u0111\u00e3 c\u00f3 suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn.<\/p>\n<p>Rifampicin l\u00e0m thay \u0111\u1ed5i chuy\u1ec3n h\u00f3a losartan, t\u1eeb \u0111\u00f3 khi\u1ebfn l\u01b0\u1ee3ng ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh trong c\u01a1 th\u1ec3 gi\u1ea3m xu\u1ed1ng. Fluconazole c\u0169ng c\u00f3 th\u1ec3 g\u00e2y gi\u1ea3m n\u1ed3ng \u0111\u1ed9 ch\u1ea5t chuy\u1ec3n h\u00f3a n\u00e0y do \u1ee9c ch\u1ebf CYP2C9.<\/p>\n<p>Ch\u01b0a ghi nh\u1eadn t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng gi\u1eefa losartan v\u1edbi hydrochlorothiazide, digoxin, warfarin, cimetidin, phenobarbital, ketoconazole ho\u1eb7c erythromycin.<\/p>\n<p>Khi s\u1eed d\u1ee5ng amlodipine c\u00f9ng simvastatin, m\u1ee9c ph\u01a1i nhi\u1ec5m simvastatin c\u00f3 th\u1ec3 t\u0103ng kho\u1ea3ng 77%. Do \u0111\u00f3, li\u1ec1u simvastatin \u1edf b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng amlodipine kh\u00f4ng n\u00ean v\u01b0\u1ee3t qu\u00e1 20 mg\/ng\u00e0y.<\/p>\n<p>Sildenafil c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi amlodipine nh\u01b0ng t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a hai thu\u1ed1c c\u00f3 th\u1ec3 c\u1ed9ng h\u1ee3p.<\/p>\n<p>Cimetidin, n\u01b0\u1edbc b\u01b0\u1edfi v\u00e0 thu\u1ed1c kh\u00e1ng acid ch\u1ee9a magnesi ho\u1eb7c nh\u00f4m kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a amlodipine.<\/p>\n<p>Amlodipine kh\u00f4ng l\u00e0m thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 ho\u1eb7c \u0111\u1ed9 thanh th\u1ea3i th\u1eadn c\u1ee7a digoxin v\u00e0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn \u0111\u00e1p \u1ee9ng prothrombin c\u1ee7a warfarin.<\/p>\n<p>Vi\u1ec7c d\u00f9ng \u0111\u1ed3ng th\u1eddi amlodipine v\u1edbi atorvastatin kh\u00f4ng l\u00e0m thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 c\u00e1c th\u00f4ng s\u1ed1 d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a atorvastatin.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Cozaar XQ kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng trong thai k\u1ef3. C\u00e1c thu\u1ed1c t\u00e1c \u0111\u1ed9ng l\u00ean h\u1ec7 renin-angiotensin, \u0111\u1eb7c bi\u1ec7t khi d\u00f9ng t\u1eeb tam c\u00e1 nguy\u1ec7t th\u1ee9 hai, c\u00f3 th\u1ec3 g\u00e2y t\u1ed5n th\u01b0\u01a1ng nghi\u00eam tr\u1ecdng ho\u1eb7c t\u1eed vong cho thai nhi. Khi ph\u00e1t hi\u1ec7n c\u00f3 thai, c\u1ea7n ng\u1eebng thu\u1ed1c c\u00e0ng s\u1edbm c\u00e0ng t\u1ed1t.<\/p>\n<p>Nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt ghi nh\u1eadn losartan c\u00f3 th\u1ec3 g\u00e2y t\u1ed5n th\u01b0\u01a1ng ho\u1eb7c t\u1eed vong \u1edf thai v\u00e0 con non, \u0111\u01b0\u1ee3c cho l\u00e0 li\u00ean quan \u0111\u1ebfn t\u00e1c \u0111\u1ed9ng tr\u00ean h\u1ec7 renin-angiotensin. Hi\u1ec7n ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u v\u1ec1 \u0111\u1ed9 an to\u00e0n c\u1ee7a amlodipine \u1edf ph\u1ee5 n\u1eef mang thai.<\/p>\n<p>Kh\u1ea3 n\u0103ng ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 c\u1ee7a amlodipine v\u00e0 losartan ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh. V\u00ec r\u1ee7i ro g\u00e2y h\u1ea1i cho tr\u1ebb nh\u1ecf do nhi\u1ec1u lo\u1ea1i thu\u1ed1c c\u00f3 th\u1ec3 \u0111i qua \u0111\u01b0\u1eddng s\u1eefa, vi\u1ec7c ng\u01b0ng cho con b\u00fa ho\u1eb7c ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c c\u1ea7n \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc c\u1ea9n th\u1eadn d\u1ef1a tr\u00ean t\u1ea7m quan tr\u1ecdng c\u1ee7a li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u nghi\u00ean c\u1ee9u ch\u00ednh th\u1ee9c v\u1ec1 t\u00e1c \u0111\u1ed9ng c\u1ee7a Cozaar XQ \u0111\u1ed1i v\u1edbi kh\u1ea3 n\u0103ng l\u00e1i xe c\u0169ng nh\u01b0 \u0111i\u1ec1u khi\u1ec3n m\u00e1y m\u00f3c. M\u1eb7c d\u00f9 v\u1eady, m\u1ed9t s\u1ed1 ph\u1ea3n \u1ee9ng kh\u00f4ng mong mu\u1ed1n \u0111\u00e3 ghi nh\u1eadn t\u1eeb thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng t\u1eadp trung ho\u1eb7c \u0111i\u1ec1u khi\u1ec3n c\u1ee7a b\u1ec7nh nh\u00e2n. C\u1ea7n l\u01b0u \u00fd r\u1eb1ng m\u1ee9c \u0111\u1ed9 \u1ea3nh h\u01b0\u1edfng n\u00e0y ph\u1ee5 thu\u1ed9c v\u00e0o c\u01a1 \u0111\u1ecba v\u00e0 m\u1ee9c \u0111\u1ed9 \u0111\u00e1p \u1ee9ng ri\u00eang c\u1ee7a t\u1eebng ng\u01b0\u1eddi.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Hi\u1ec7n ch\u01b0a c\u00f3 d\u1eef li\u1ec7u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 t\u00ecnh tr\u1ea1ng qu\u00e1 li\u1ec1u Cozaar XQ \u1edf ng\u01b0\u1eddi. C\u00e1ch x\u1eed tr\u00ed ch\u1ee7 y\u1ebfu d\u1ef1a tr\u00ean bi\u1ec3u hi\u1ec7n qu\u00e1 li\u1ec1u c\u1ee7a t\u1eebng ho\u1ea1t ch\u1ea5t.<\/p>\n<p>Losartan c\u00f3 th\u1ec3 g\u00e2y t\u1ee5t huy\u1ebft \u00e1p, th\u01b0\u1eddng k\u00e8m nh\u1ecbp tim nhanh; trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n nh\u1ecbp tim ch\u1eadm do t\u0103ng ho\u1ea1t \u0111\u1ed9ng ph\u00f3 giao c\u1ea3m. Khi x\u1ea3y ra t\u1ee5t huy\u1ebft \u00e1p, c\u1ea7n \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 v\u00e0 theo d\u00f5i ph\u00f9 h\u1ee3p. Losartan v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh kh\u00f4ng \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf b\u1eb1ng th\u1ea9m t\u00e1ch m\u00e1u.<\/p>\n<p>Amlodipine khi d\u00f9ng qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 g\u00e2y gi\u00e3n m\u1ea1ch ngo\u1ea1i bi\u00ean qu\u00e1 m\u1ee9c, d\u1eabn \u0111\u1ebfn t\u1ee5t huy\u1ebft \u00e1p nghi\u00eam tr\u1ecdng v\u00e0 nh\u1ecbp tim nhanh ph\u1ea3n x\u1ea1.<\/p>\n<p>Khi nghi ng\u1edd qu\u00e1 li\u1ec1u amlodipine, c\u1ea7n theo d\u00f5i s\u00e1t ch\u1ee9c n\u0103ng tim m\u1ea1ch v\u00e0 h\u00f4 h\u1ea5p, \u0111\u1ed3ng th\u1eddi ki\u1ec3m tra huy\u1ebft \u00e1p th\u01b0\u1eddng xuy\u00ean. N\u1ebfu t\u1ee5t huy\u1ebft \u00e1p, c\u1ea7n \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 tu\u1ea7n ho\u00e0n nh\u01b0 n\u00e2ng cao chi v\u00e0 truy\u1ec1n d\u1ecbch ph\u00f9 h\u1ee3p.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p t\u1ee5t huy\u1ebft \u00e1p kh\u00f4ng c\u1ea3i thi\u1ec7n v\u1edbi c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 th\u00f4ng th\u01b0\u1eddng, c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc s\u1eed d\u1ee5ng thu\u1ed1c co m\u1ea1ch nh\u01b0 phenylephrin, \u0111\u1ed3ng th\u1eddi l\u01b0u \u00fd t\u00ecnh tr\u1ea1ng th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n v\u00e0 l\u01b0\u1ee3ng n\u01b0\u1edbc ti\u1ec3u.<\/p>\n<p>Do amlodipine c\u00f3 t\u1ef7 l\u1ec7 li\u00ean k\u1ebft protein cao, th\u1ea9m t\u00e1ch m\u00e1u \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3 \u0111\u00e1ng k\u1ec3 trong x\u1eed tr\u00ed qu\u00e1 li\u1ec1u.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Cozaar XQ 5\/50mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Cozaar XQ 5\/50mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Cozaar XQ 5\/50mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>Thu\u1ed1c Cozaar XQ 5\/50mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Cozaar XQ 5\/50mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Cozaar XQ 5\/50mg c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Cozaar XQ 5\/50mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Cozaar XQ 5\/50mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/troysar-am\/\">Troysar AM<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Amlodipine 5mg v\u00e0 Losartan kali 50mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Troikaa Pharmaceuticals Ltd, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/telorssa-100mg-5mg\/\">Telorssa 100mg\/5mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Amlodipine 5mg v\u00e0 Losartan kali 100mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi KRKA, d. d., Novo mesto, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Zhang S, Li Y, Xu X, Xu R, Zhang L, Wan X, Yao Z, Sun Y, Liu Y, Bin J, Wang Z, Li S, Yang P, Xu X, Liang W, Gao X, Li X, Jia M, Ma G, Gu X, Hong C (2023). Efficacy and safety of single-pill amlodipine\/losartan versus losartan in patients with inadequately controlled hypertension after losartan treatment: a multicenter, double-blind, randomized phase III clinical trial. Front Cardiovasc Med. Truy c\u1eadp ng\u00e0y 8 th\u00e1ng 10 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37404731\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37404731\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Cozaar XQ 5\/50mg ch\u1ee9a losartan v\u00e0 amlodipine, \u0111\u01b0\u1ee3c d\u00f9ng \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n \u1edf ng\u01b0\u1eddi l\u1edbn khi ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p ch\u01b0a \u0111\u1ea1t y\u00eau c\u1ea7u v\u1edbi \u0111\u01a1n tr\u1ecb li\u1ec7u<\/p>\n","protected":false},"author":1,"featured_media":163622,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-163621","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/163621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=163621"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/163622"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=163621"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=163621"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=163621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}