{"id":162566,"date":"2026-09-11T10:11:35","date_gmt":"2026-09-11T03:11:35","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=162566"},"modified":"2026-09-11T10:13:11","modified_gmt":"2026-09-11T03:13:11","slug":"bosfuxim-500","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/bosfuxim-500\/","title":{"rendered":"Bosfuxim 500"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Bosfuxim 500 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Boston Vi\u1ec7t Nam c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110198523<\/b><\/p>\n<h2>Bosfuxim 500 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i vi\u00ean <b>Bosfuxim 500<\/b> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Cefuroxim (d\u01b0\u1edbi d\u1ea1ng cefuroxim axetil): 500mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110198523<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Bosfuxim 500<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Ho\u1ea1t ch\u1ea5t cefuroxime c\u00f3 t\u00e1c d\u1ee5ng ti\u00eau di\u1ec7t vi khu\u1ea9n \u0111\u01b0\u1ee3c t\u1ea1o ra nh\u1edd qu\u00e1 tr\u00ecnh enzym esterase th\u1ee7y ph\u00e2n cefuroxime axetil. Thu\u1ed1c can thi\u1ec7p v\u00e0o giai \u0111o\u1ea1n t\u1ed5ng h\u1ee3p peptidoglycan &#8211; th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ea5u t\u1ea1o n\u00ean v\u00e1ch t\u1ebf b\u00e0o vi khu\u1ea9n &#8211; th\u00f4ng qua li\u00ean k\u1ebft v\u1edbi c\u00e1c PBP (protein g\u1eafn penicillin), t\u1eeb \u0111\u00f3 l\u00e0m v\u1ee1 c\u1ea5u tr\u00fac th\u00e0nh t\u1ebf b\u00e0o.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Ho\u1ea1t ch\u1ea5t cefuroxime \u0111i v\u00e0o h\u1ec7 tu\u1ea7n ho\u00e0n nh\u1edd qu\u00e1 tr\u00ecnh th\u1ee7y ph\u00e2n nhanh cefuroxime axetil t\u1ea1i m\u00e1u v\u00e0 ni\u00eam m\u1ea1c ru\u1ed9t sau khi h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Vi\u1ec7c d\u00f9ng thu\u1ed1c li\u1ec1n sau b\u1eefa \u0103n gi\u00fap t\u1ed1i \u0111a h\u00f3a kh\u1ea3 n\u0103ng h\u1ea5p thu. N\u1ebfu u\u1ed1ng c\u00f9ng th\u1ef1c ph\u1ea9m, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft thanh s\u1ebd xu\u1ea5t hi\u1ec7n sau 2 \u0111\u1ebfn 3 gi\u1edd, \u0111\u1ea1t m\u1ee9c 2,1mg\/l; 4,1mg\/1; 7,0mg\/1 v\u00e0 13,6mg\/1 t\u01b0\u01a1ng \u1ee9ng v\u1edbi c\u00e1c m\u1ee9c li\u1ec1u 125mg, 250mg, 500mg v\u00e0 1 g.<\/p>\n<p>So v\u1edbi vi\u00ean n\u00e9n, d\u1ea1ng h\u1ed7n d\u1ecbch u\u1ed1ng l\u00e0m gi\u1ea3m sinh kh\u1ea3 d\u1ee5ng to\u00e0n th\u00e2n (th\u1ea5p h\u01a1n t\u1eeb 4-17%), d\u1eabn t\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t m\u1ee9c th\u1ea5p h\u01a1n v\u00e0 ch\u1eadm h\u01a1n. V\u00ec thi\u1ebfu t\u00ednh t\u01b0\u01a1ng \u0111\u01b0\u01a1ng sinh h\u1ecdc tr\u00ean ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh kh\u1ecfe m\u1ea1nh, kh\u00f4ng th\u1ec3 t\u1ef1 \u00fd thay th\u1ebf hai d\u1ea1ng b\u00e0o ch\u1ebf n\u00e0y d\u1ef1a tr\u00ean s\u1ed1mg t\u01b0\u01a1ng \u0111\u01b0\u01a1ng. Cefuroxime \u0111\u1ea1t \u0111\u1eb7c t\u00ednh d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc tuy\u1ebfn t\u00ednh trong kho\u1ea3ng li\u1ec1u 125-1000mg v\u00e0 kh\u00f4ng g\u00e2y t\u00edch l\u0169y khi s\u1eed d\u1ee5ng l\u1eb7p l\u1ea1i c\u00e1c li\u1ec1u 250-500mg.<\/p>\n<p>T\u00f9y v\u00e0o k\u1ef9 thu\u1eadt th\u1eed nghi\u1ec7m, m\u1ee9c \u0111\u1ed9 li\u00ean k\u1ebft protein c\u1ee7a cefuroxime \u0111\u01b0\u1ee3c ghi nh\u1eadn dao \u0111\u1ed9ng t\u1eeb 33% \u0111\u1ebfn 50%.<\/p>\n<p>Khi cho 12 t\u00ecnh nguy\u1ec7n vi\u00ean kh\u1ecfe m\u1ea1nh u\u1ed1ng m\u1ed9t vi\u00ean n\u00e9n cefuroxime axetil 500 mg (li\u1ec1u \u0111\u01a1n), th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 tuy\u1ec7t \u0111\u1ed1i \u0111o \u0111\u01b0\u1ee3c l\u00e0 50L (\u0111\u1ed9 bi\u1ebfn thi\u00ean CV% = 28%). Thu\u1ed1c th\u00e2m nh\u1eadp t\u1ed1t v\u00e0 duy tr\u00ec n\u1ed3ng \u0111\u1ed9 v\u01b0\u1ee3t ng\u01b0\u1ee1ng MIC (n\u1ed3ng \u0111\u1ed9 \u1ee9c ch\u1ebf t\u1ed1i thi\u1ec3u) c\u1ee7a c\u00e1c ch\u1ee7ng vi khu\u1ea9n th\u01b0\u1eddng g\u1eb7p t\u1ea1i: ni\u00eam m\u1ea1c ph\u1ebf qu\u1ea3n, amidan, m\u00f4 xoang, \u0111\u1eddm, x\u01b0\u01a1ng, m\u1eadt, th\u1ee7y d\u1ecbch, d\u1ecbch m\u00e0ng ph\u1ed5i, d\u1ecbch k\u1ebd c\u00f9ng c\u00e1c d\u1ecbch ho\u1ea1t kh\u1edbp. \u0110\u1eb7c bi\u1ec7t, khi x\u1ea3y ra t\u00ecnh tr\u1ea1ng vi\u00eam m\u00e0ng n\u00e3o, thu\u1ed1c c\u00f3 th\u1ec3 xuy\u00ean qua h\u00e0ng r\u00e0o m\u00e1u &#8211; n\u00e3o.<\/p>\n<p>Ho\u1ea1t ch\u1ea5t kh\u00f4ng tr\u1ea3i qua qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a trong c\u01a1 th\u1ec3. Th\u1eddi gian b\u00e1n th\u1ea3i (t1\/2) c\u1ee7a thu\u1ed1c trong huy\u1ebft thanh duy tr\u00ec t\u1eeb 1 \u0111\u1ebfn 1,5 gi\u1edd.<\/p>\n<p>Cefuroxime \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf kh\u1ecfi c\u01a1 th\u1ec3 th\u00f4ng qua c\u1ea3 c\u01a1 ch\u1ebf b\u00e0i ti\u1ebft \u1edf \u1ed1ng th\u1eadn l\u1eabn l\u1ecdc t\u1ea1i c\u1ea7u th\u1eadn, v\u1edbi ch\u1ec9 s\u1ed1 \u0111\u1ed9 thanh th\u1ea3i qua th\u1eadn dao \u0111\u1ed9ng kho\u1ea3ng 125-148 mL\/ph\u00fat\/1,73 m\u00b2.<\/p>\n<h2>Thu\u1ed1c Bosfuxim 500 tr\u1ecb b\u1ec7nh g\u00ec?<\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb \u0111\u01b0\u1eddng u\u1ed1ng khi:<\/p>\n<ul>\n<li>Nhi\u1ec5m khu\u1ea9n tai &#8211; m\u0169i &#8211; h\u1ecdng: vi\u00eam h\u1ecdng, vi\u00eam amidan, vi\u00eam xoang, vi\u00eam tai gi\u1eefa.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p d\u01b0\u1edbi: \u0111\u1ee3t c\u1ea5p c\u1ee7a vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n, vi\u00eam ph\u1ebf qu\u1ea3n c\u1ea5p v\u00e0 vi\u00eam ph\u1ed5i.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u: vi\u00eam th\u1eadn &#8211; b\u1ec3 th\u1eadn, vi\u00eam ni\u1ec7u \u0111\u1ea1o, vi\u00eam b\u00e0ng quang.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m: ch\u1ed1c l\u1edf, nh\u1ecdt.<\/li>\n<li>B\u1ec7nh l\u1eadu, vi\u00eam c\u1ed5 t\u1eed cung do l\u1eadu c\u1ea7u v\u00e0 vi\u00eam ni\u1ec7u \u0111\u1ea1o c\u1ea5p kh\u00f4ng bi\u1ebfn ch\u1ee9ng.<\/li>\n<\/ul>\n<p>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh Lyme \u1edf th\u1eddi k\u1ef3 \u0111\u1ea7u \u0111\u1ec3 ng\u0103n ch\u1eb7n nguy c\u01a1 chuy\u1ec3n sang giai \u0111o\u1ea1n mu\u1ed9n. Ngo\u00e0i ra, Bosfuxim c\u00f2n c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng l\u00e0m li\u1ec7u ph\u00e1p ti\u1ebfp n\u1ed1i sau khi d\u00f9ng cefuroxime ti\u00eam ban \u0111\u1ea7u, nh\u1ea5t l\u00e0 \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi b\u1ec7nh vi\u00eam ph\u1ed5i hay \u0111\u1ee3t c\u1ea5p vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n c\u00f3 ch\u1ec9 \u0111\u1ecbnh \u0111\u1ed5i sang d\u1ea1ng u\u1ed1ng.<\/p>\n<figure id=\"attachment_162574\" aria-describedby=\"caption-attachment-162574\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-162574\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/09\/Bosfuxim-500.jpg\" alt=\"Bosfuxim 500\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/09\/Bosfuxim-500.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/09\/Bosfuxim-500-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/09\/Bosfuxim-500-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/09\/Bosfuxim-500-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/09\/Bosfuxim-500-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-162574\" class=\"wp-caption-text\">Bosfuxim 500 \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u lo\u1ea1i nhi\u1ec5m khu\u1ea9n do vi khu\u1ea9n nh\u1ea1y c\u1ea3m<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec7u tr\u00ecnh \u0111i\u1ec1u tr\u1ecb th\u00f4ng th\u01b0\u1eddng k\u00e9o d\u00e0i kho\u1ea3ng 7 ng\u00e0y (c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh trong kho\u1ea3ng 5-10 ng\u00e0y t\u00f9y m\u1ee9c \u0111\u1ed9 nhi\u1ec5m tr\u00f9ng).<\/p>\n<p>\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 40 kg tr\u1edf l\u00ean:<\/p>\n<ul>\n<li>Nhi\u1ec5m tr\u00f9ng th\u00f4ng th\u01b0\u1eddng, nhi\u1ec5m tr\u00f9ng ti\u1ebft ni\u1ec7u, vi\u00eam th\u1eadn &#8211; b\u1ec3 th\u1eadn, vi\u00eam ph\u1ebf qu\u1ea3n nh\u1eb9 \u0111\u1ebfn v\u1eeba: D\u00f9ng 250mg\/l\u1ea7n, u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y.<\/li>\n<li>Nhi\u1ec5m tr\u00f9ng h\u00f4 h\u1ea5p d\u01b0\u1edbi m\u1ee9c \u0111\u1ed9 n\u1eb7ng ho\u1eb7c nghi ng\u1edd vi\u00eam ph\u1ed5i: D\u00f9ng 1 vi\u00ean lo\u1ea1i 500 m\u1ed7i l\u1ea7n, u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y.<\/li>\n<li>B\u1ec7nh l\u1eadu ch\u01b0a bi\u1ebfn ch\u1ee9ng: U\u1ed1ng li\u1ec1u duy nh\u1ea5t 2 vi\u00ean lo\u1ea1i 500.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh Lyme (ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb tr\u00ean 12 tu\u1ed5i): D\u00f9ng 1 vi\u00ean lo\u1ea1i 500 m\u1ed7i l\u1ea7n, u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y trong 14 ng\u00e0y (th\u1eddi gian \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 dao \u0111\u1ed9ng t\u1eeb 10-21 ng\u00e0y).<\/li>\n<\/ul>\n<p>\u0110\u1ed1i v\u1edbi tr\u1ebb em t\u1eeb 3 th\u00e1ng \u0111\u1ebfn 12 tu\u1ed5i (d\u01b0\u1edbi 40 kg):<\/p>\n<ul>\n<li>Nhi\u1ec5m tr\u00f9ng m\u1ee9c \u0111\u1ed9 nh\u1eb9\/th\u00f4ng th\u01b0\u1eddng: D\u00f9ng 10mg\/kg\/l\u1ea7n, u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y (m\u1ee9c t\u1ed1i \u0111a 125mg\/l\u1ea7n).<\/li>\n<li>Vi\u00eam tai gi\u1eefa ho\u1eb7c nhi\u1ec5m tr\u00f9ng n\u1eb7ng: D\u00f9ng 15mg\/kg\/l\u1ea7n, u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y (m\u1ee9c t\u1ed1i \u0111a 250mg\/l\u1ea7n).<\/li>\n<li>Nhi\u1ec5m b\u1ec7nh Lyme: D\u00f9ng 15mg\/kg\/l\u1ea7n, u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y li\u00ean t\u1ee5c trong 14 ng\u00e0y (m\u1ee9c t\u1ed1i \u0111a 250mg\/l\u1ea7n).<\/li>\n<li>Vi\u00eam th\u1eadn &#8211; b\u1ec3 th\u1eadn: D\u00f9ng 15mg\/kg\/l\u1ea7n, u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y trong 10-14 ng\u00e0y (m\u1ee9c t\u1ed1i \u0111a 250mg\/l\u1ea7n).<\/li>\n<\/ul>\n<p><i>L\u01b0u \u00fd:<\/i> Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u \u0111\u1ed9 an to\u00e0n cho tr\u1ebb d\u01b0\u1edbi 3 th\u00e1ng tu\u1ed5i. Tr\u00e1nh b\u1ebb ho\u1eb7c nghi\u1ec1n nh\u1ecf vi\u00ean thu\u1ed1c v\u00ec d\u1ea1ng b\u00e0o ch\u1ebf n\u00e0y kh\u00f4ng th\u00edch h\u1ee3p cho tr\u1ebb nh\u1ecf hay b\u1ec7nh nh\u00e2n kh\u00f3 nu\u1ed1t.<\/p>\n<p>Li\u1ec7u ph\u00e1p n\u1ed1i ti\u1ebfp sau khi ti\u00eam cefuroxime:<\/p>\n<ul>\n<li>B\u1ec7nh vi\u00eam ph\u1ed5i: Sau 48-72 gi\u1edd d\u00f9ng cefuroxime natri \u0111\u01b0\u1eddng ti\u00eam, khi l\u00e2m s\u00e0ng \u1ed5n \u0111\u1ecbnh c\u00f3 th\u1ec3 chuy\u1ec3n sang u\u1ed1ng 1 vi\u00ean lo\u1ea1i 500 x 2 l\u1ea7n\/ng\u00e0y trong 7-10 ng\u00e0y.<\/li>\n<li>\u0110\u1ee3t b\u00f9ng ph\u00e1t c\u1ea5p c\u1ee7a vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n: Sau 48-72 gi\u1edd ti\u00eam truy\u1ec1n, chuy\u1ec3n sang u\u1ed1ng 500mg x 2 l\u1ea7n\/ng\u00e0y trong 5-10 ng\u00e0y.<\/li>\n<li>Th\u1eddi gian d\u00f9ng thu\u1ed1c c\u1ee5 th\u1ec3 s\u1ebd c\u0103n c\u1ee9 v\u00e0o ti\u1ebfn tri\u1ec3n l\u00e2m s\u00e0ng v\u00e0 m\u1ee9c \u0111\u1ed9 nhi\u1ec5m tr\u00f9ng.<\/li>\n<\/ul>\n<p>B\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn: C\u1ea7n gi\u00e3n kho\u1ea3ng c\u00e1ch gi\u1eefa c\u00e1c l\u1ea7n u\u1ed1ng thu\u1ed1c d\u1ef1a theo ch\u1ec9 s\u1ed1 \u0111\u1ed9 thanh th\u1ea3i creatinin (CrCl):<\/p>\n<ul>\n<li>CrCl \u2265 30 mL\/ph\u00fat: D\u00f9ng li\u1ec1u Bosfuxim chu\u1ea9n, kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh.<\/li>\n<li>CrCl t\u1eeb 10-29 mL\/ph\u00fat: D\u00f9ng 1 li\u1ec1u Bosfuxim chu\u1ea9n m\u1ed7i 24 gi\u1edd.<\/li>\n<li>CrCl &lt; 10 mL\/ph\u00fat: D\u00f9ng 1 li\u1ec1u chu\u1ea9n Bosfuxim m\u1ed7i 48 gi\u1edd.<\/li>\n<li>B\u1ec7nh nh\u00e2n ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o: U\u1ed1ng th\u00eam 1 li\u1ec1u b\u1ed5 sung sau m\u1ed7i \u0111\u1ee3t l\u1ecdc m\u00e1u.<\/li>\n<\/ul>\n<p>B\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng gan: D\u1eef li\u1ec7u tr\u00ean nh\u00f3m \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y c\u00f2n h\u1ea1n ch\u1ebf. Tuy nhi\u00ean, v\u00ec cefuroxime \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft ch\u1ee7 y\u1ebfu qua \u0111\u01b0\u1eddng th\u1eadn, vi\u1ec7c suy gi\u1ea3m ch\u1ee9c n\u0103ng gan d\u1ef1 ki\u1ebfn kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng l\u1edbn \u0111\u1ebfn qu\u00e1 tr\u00ecnh th\u1ea3i tr\u1eeb thu\u1ed1c.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p><b>Vi\u00ean n\u00e9n Bosfuxim 500 <\/b>\u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng sau \u0103n<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Bosfuxim 500 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi cefuroxime hay t\u00e1 d\u01b0\u1ee3c c\u00f3 trong Bosfuxim 500 ho\u1eb7c kh\u00e1ng sinh nh\u00f3m cephalosporin<\/p>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n t\u1eebng g\u1eb7p ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn n\u1eb7ng (v\u00ed d\u1ee5: s\u1ed1c ph\u1ea3n v\u1ec7) v\u1edbi c\u00e1c kh\u00e1ng sinh h\u1ecd beta-lactam (c\u00e1c d\u1eabn xu\u1ea5t carbapenem, penicillin, \u2026).<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Tr\u01b0\u1edbc khi k\u00ea Cefuroxime, c\u1ea7n khai th\u00e1c ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi Penicillin, Cephalosporin v\u00e0 c\u00e1c kh\u00e1ng sinh beta-lactam kh\u00e1c. Nh\u1eefng tr\u01b0\u1eddng h\u1ee3p t\u1eebng c\u00f3 ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn nghi\u00eam tr\u1ecdng v\u1edbi c\u00e1c thu\u1ed1c n\u00e0y kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng Cefuroxime. N\u1ebfu x\u1ea3y ra ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng n\u1eb7ng trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, ph\u1ea3i ng\u1eebng thu\u1ed1c ngay v\u00e0 \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p c\u1ea5p c\u1ee9u c\u1ea7n thi\u1ebft.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ec7nh \u0111i\u1ec1u tr\u1ecb Lyme b\u1eb1ng Cefuroxime c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3n \u1ee9ng Jarisch-Herxheimer. \u0110\u00e2y l\u00e0 hi\u1ec7n t\u01b0\u1ee3ng x\u1ea3y ra do vi khu\u1ea9n Borrelia burgdorferi b\u1ecb ti\u00eau di\u1ec7t d\u01b0\u1edbi t\u00e1c \u0111\u1ed9ng c\u1ee7a kh\u00e1ng sinh v\u00e0 ph\u1ea3n \u1ee9ng th\u01b0\u1eddng c\u00f3 t\u00ednh ch\u1ea5t t\u1ea1m th\u1eddi, t\u1ef1 thuy\u00ean gi\u1ea3m.<\/p>\n<p>Vi\u1ec7c d\u00f9ng Cefuroxime trong th\u1eddi gian d\u00e0i c\u00f3 th\u1ec3 l\u00e0m thay \u0111\u1ed5i h\u1ec7 vi sinh, t\u1ea1o \u0111i\u1ec1u ki\u1ec7n cho Candida ho\u1eb7c c\u00e1c vi khu\u1ea9n kh\u00e1ng thu\u1ed1c nh\u01b0 Enterococci v\u00e0 Clostridium difficile ph\u00e1t tri\u1ec3n. Ti\u00eau ch\u1ea3y xu\u1ea5t hi\u1ec7n trong ho\u1eb7c sau khi \u0111i\u1ec1u tr\u1ecb c\u1ea7n \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 \u0111\u1ec3 lo\u1ea1i tr\u1eeb vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c. Khi nghi ng\u1edd t\u00ecnh tr\u1ea1ng n\u00e0y, n\u00ean ng\u1eebng Cefuroxime, c\u00e2n nh\u1eafc \u0111i\u1ec1u tr\u1ecb \u0111\u1eb7c hi\u1ec7u v\u00e0 tr\u00e1nh d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf nhu \u0111\u1ed9ng ru\u1ed9t.<\/p>\n<p>M\u1ed9t s\u1ed1 x\u00e9t nghi\u1ec7m c\u00f3 th\u1ec3 b\u1ecb \u1ea3nh h\u01b0\u1edfng trong th\u1eddi gian s\u1eed d\u1ee5ng Cefuroxime. Thu\u1ed1c c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m ph\u1ea3n \u1ee9ng Coombs tr\u1edf n\u00ean d\u01b0\u01a1ng t\u00ednh, t\u1eeb \u0111\u00f3 g\u00e2y kh\u00f3 kh\u0103n cho vi\u1ec7c x\u00e1c \u0111\u1ecbnh t\u01b0\u01a1ng h\u1ee3p khi truy\u1ec1n m\u00e1u. Khi \u0111\u1ecbnh l\u01b0\u1ee3ng glucose m\u00e1u ho\u1eb7c huy\u1ebft t\u01b0\u01a1ng, n\u00ean l\u1ef1a ch\u1ecdn ph\u01b0\u01a1ng ph\u00e1p glucose oxidase ho\u1eb7c hexokinase thay cho ferricyanide \u0111\u1ec3 tr\u00e1nh nguy c\u01a1 k\u1ebft qu\u1ea3 \u00e2m t\u00ednh gi\u1ea3.<\/p>\n<p>M\u1ed7i vi\u00ean thu\u1ed1c cung c\u1ea5p l\u01b0\u1ee3ng natri d\u01b0\u1edbi 23 mg, do \u0111\u00f3 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c xem l\u00e0 Bosfuxim c\u00f3 h\u00e0m l\u01b0\u1ee3ng natri kh\u00f4ng \u0111\u00e1ng k\u1ec3.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Ph\u1ed5 bi\u1ebfn: Men gan t\u0103ng t\u1ea1m th\u1eddi, \u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n, ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u, ti\u00eau ch\u1ea3y, gia t\u0103ng b\u1ea1ch c\u1ea7u \u00e1i toan, b\u00f9ng ph\u00e1t n\u1ea5m Candida.<\/p>\n<p>Kh\u00f4ng ph\u1ed5 bi\u1ebfn: N\u00f4n m\u1eeda, xu\u1ea5t hi\u1ec7n ban da, s\u1ee5t gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u, suy gi\u1ea3m ti\u1ec3u c\u1ea7u, k\u1ebft qu\u1ea3 ph\u1ea3n \u1ee9ng Coombs d\u01b0\u01a1ng t\u00ednh.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: Vi\u00eam \u0111\u1ea1i tr\u00e0ng m\u00e0ng gi\u1ea3, ng\u1ee9a ng\u00e1y, n\u1ed5i m\u1ec1 \u0111ai.<\/p>\n<p>R\u1ea5t hi\u1ebfm: Ho\u1ea1i t\u1eed th\u01b0\u1ee3ng b\u00ec nhi\u1ec5m \u0111\u1ed9c, h\u1ed3ng ban \u0111a d\u1ea1ng, vi\u00eam gan, v\u00e0ng da (ch\u1ee7 y\u1ebfu do t\u1eafc m\u1eadt), h\u1ed9i ch\u1ee9ng SJS, s\u1ed1c ph\u1ea3n v\u1ec7, b\u1ec7nh huy\u1ebft thanh, s\u1ed1t do ph\u1ea3n \u1ee9ng v\u1edbi thu\u1ed1c, thi\u1ebfu m\u00e1u tan m\u00e1u.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Khi ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c l\u00e0m gi\u1ea3m acid d\u1ecbch v\u1ecb, kh\u1ea3 n\u0103ng h\u1ea5p thu cefuroxime axetil c\u00f3 th\u1ec3 gi\u1ea3m, \u0111\u1ed3ng th\u1eddi l\u00e0m m\u1ea5t l\u1ee3i th\u1ebf v\u1ec1 sinh kh\u1ea3 d\u1ee5ng \u0111\u1ea1t \u0111\u01b0\u1ee3c khi d\u00f9ng thu\u1ed1c sau b\u1eefa \u0103n.<\/p>\n<p>Do l\u00e0m thay \u0111\u1ed5i h\u1ec7 vi khu\u1ea9n \u0111\u01b0\u1eddng ru\u1ed9t, cefuroxime axetil c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m qu\u00e1 tr\u00ecnh t\u00e1i h\u1ea5p thu oestrogen, t\u1eeb \u0111\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 tr\u00e1nh thai c\u1ee7a thu\u1ed1c u\u1ed1ng tr\u00e1nh thai k\u1ebft h\u1ee3p.<\/p>\n<p>N\u00ean x\u00e1c \u0111\u1ecbnh glucose m\u00e1u\/huy\u1ebft t\u01b0\u01a1ng b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p hexokinase ho\u1eb7c glucose oxidase, v\u00ec ph\u01b0\u01a1ng ph\u00e1p ferricyanide c\u00f3 th\u1ec3 cho k\u1ebft qu\u1ea3 \u00e2m t\u00ednh gi\u1ea3 trong th\u1eddi gian s\u1eed d\u1ee5ng Luman Cefuroxime 500.<\/p>\n<p>Ph\u01b0\u01a1ng ph\u00e1p alkaline picrate d\u00f9ng \u0111\u1ec3 \u0111\u1ecbnh l\u01b0\u1ee3ng creatinin kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi thu\u1ed1c n\u00e0y.<\/p>\n<p>Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi Probenecid. S\u1ef1 ph\u1ed1i h\u1ee3p n\u00e0y l\u00e0m gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i cefuroxime qua th\u1eadn, d\u1eabn \u0111\u1ebfn k\u00e9o d\u00e0i \u0111\u00e1ng k\u1ec3 th\u1eddi gian b\u00e1n<\/p>\n<p>Ch\u1ec9 s\u1ed1 INR c\u00f3 nguy c\u01a1 b\u1ecb t\u0103ng cao n\u1ebfu b\u1ec7nh nh\u00e2n k\u1ebft h\u1ee3p thu\u1ed1c v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p ch\u1ed1ng \u0111\u00f4ng d\u1ea1ng u\u1ed1ng.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Nh\u01b0 m\u1ecdi lo\u1ea1i thu\u1ed1c kh\u00e1c, Bosfuxim c\u1ea7n \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng th\u1eadn tr\u1ecdng trong giai \u0111o\u1ea1n \u0111\u1ea7u c\u1ee7a thai k\u1ef3, m\u1eb7c d\u00f9 ch\u01b0a c\u00f3 b\u1eb1ng ch\u1ee9ng th\u1ef1c nghi\u1ec7m n\u00e0o cho th\u1ea5y thu\u1ed1c g\u00e2y d\u1ecb d\u1ea1ng thai nhi hay t\u00e1c \u0111\u1ed9ng ti\u00eau c\u1ef1c \u0111\u1ebfn ph\u00f4i.<\/p>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Bosfuxim \u1edf b\u00e0 m\u1eb9 \u0111ang cho con b\u00fa, b\u1edfi ho\u1ea1t ch\u1ea5t cefuroxime c\u00f3 th\u1ec3 \u0111i v\u00e0o s\u1eefa m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>C\u1ea7n c\u1ea3nh b\u00e1o ng\u01b0\u1eddi b\u1ec7nh th\u1eadn tr\u1ecdng khi v\u1eadn h\u00e0nh m\u00e1y m\u00f3c hay l\u00e1i xe, b\u1edfi ho\u1ea1t ch\u1ea5t c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u00e1c d\u1ee5ng ph\u1ee5 g\u00e2y ch\u00f3ng m\u1eb7t.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>S\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u kh\u00e1ng sinh nh\u00f3m cephalosporin c\u00f3 th\u1ec3 k\u00edch th\u00edch h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng, g\u00e2y ra c\u00e1c c\u01a1n co gi\u1eadt.<\/p>\n<p>C\u00f3 th\u1ec3 h\u1ea1 n\u1ed3ng \u0111\u1ed9 cefuroxime trong m\u00e1u th\u00f4ng qua ph\u01b0\u01a1ng ph\u00e1p l\u1ecdc m\u00e1u (th\u1ea9m ph\u00e2n m\u00e1u) ho\u1eb7c l\u1ecdc m\u00e0ng b\u1ee5ng (th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c).<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Bosfuxim 500 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Bosfuxim 500 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Bosfuxim 500 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>Thu\u1ed1c Bosfuxim 500 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Bosfuxim 500 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Bosfuxim 500 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Bosfuxim 500 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Bosfuxim 500 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/fetnal-500\/\">Fetnal 500 <\/a>c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Cefuroxim 500mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Brawn Laboratories Limited, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/zanimex-500mg\/\">Zanimex 500mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Cefuroxim 500mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Imexpharm t\u1ea1i B\u00ecnh D\u01b0\u01a1ng, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>O&#8217;Callaghan CH, Sykes RB, Griffiths A, Thornton JE (1976). Cefuroxime, a new cephalosporin antibiotic: activity in vitro. Antimicrob Agents Chemother. Truy c\u1eadp ng\u00e0y 11 th\u00e1ng 6 n\u0103m 2026 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1259407\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/1259407\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bosfuxim 500 c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Cefuroxime 500mg, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb c\u00e1c t\u00ecnh tr\u1ea1ng nhi\u1ec5m tr\u00f9ng g\u00e2y ra b\u1edfi nh\u1eefng ch\u1ee7ng vi khu\u1ea9n c\u00f2n nh\u1ea1y c\u1ea3m v\u1edbi thu\u1ed1c.<\/p>\n","protected":false},"author":1,"featured_media":162571,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-162566","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/162566","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=162566"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/162571"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=162566"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=162566"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=162566"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}