{"id":161979,"date":"2026-08-21T09:09:55","date_gmt":"2026-08-21T02:09:55","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=161979"},"modified":"2026-08-21T09:11:19","modified_gmt":"2026-08-21T02:11:19","slug":"amphot-50mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/amphot-50mg\/","title":{"rendered":"Amphot 50mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Amphot 50mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Lyka Labs Limited c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-19777-16<\/b><\/p>\n<h2>Amphot 50mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i l\u1ecd\u00a0<b>Amphot 50mg<\/b> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Amphotericin B: 50mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: B\u1ed9t \u0111\u00f4ng kh\u00f4 pha ti\u00eam<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-19777-16<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd<\/p>\n<p>Xu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Amphot 50mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Amphotericin B d\u1ef1a tr\u00ean kh\u1ea3 n\u0103ng li\u00ean k\u1ebft v\u1edbi ergosterol &#8211; th\u00e0nh ph\u1ea7n sterol ch\u00ednh tr\u00ean m\u00e0ng t\u1ebf b\u00e0o n\u1ea5m, t\u1eeb \u0111\u00f3 l\u00e0m suy gi\u1ea3m v\u00e0 thay \u0111\u1ed5i t\u00ednh th\u1ea5m m\u00e0ng. B\u00ean c\u1ea1nh \u0111\u00f3, vi\u1ec7c t\u01b0\u01a1ng t\u00e1c v\u1edbi cholesterol \u1edf b\u00e0o ch\u1ea5t t\u1ebf b\u00e0o ng\u01b0\u1eddi c\u0169ng l\u00e0 m\u1ed9t nguy\u00ean nh\u00e2n g\u00e2y ra c\u00e1c ph\u1ea3n \u1ee9ng \u0111\u1ed9c t\u00ednh c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y. Nh\u1eb1m h\u1ea1n ch\u1ebf t\u00e1c d\u1ee5ng ph\u1ee5 k\u1ec3 tr\u00ean, c\u00e1c d\u1ea1ng b\u00e0o ch\u1ebf hi\u1ec7n \u0111\u1ea1i nh\u01b0 liposome hay ph\u1ee9c h\u1ee3p lipid \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u v\u00e0 \u1ee9ng d\u1ee5ng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Do kh\u1ea3 n\u0103ng h\u1ea5p thu qua \u0111\u01b0\u1eddng ru\u1ed9t r\u1ea5t th\u1ea5p, Amphotericin B h\u1ea7u nh\u01b0 ch\u1ec9 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh qua \u0111\u01b0\u1eddng ti\u00eam truy\u1ec1n t\u0129nh m\u1ea1ch trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m h\u1ec7 th\u1ed1ng nghi\u00eam tr\u1ecdng; \u0111\u01b0\u1eddng u\u1ed1ng ch\u1ee7 y\u1ebfu \u00e1p d\u1ee5ng cho t\u00e1c d\u1ee5ng t\u1ea1i ch\u1ed7 (nh\u01b0 n\u1ea5m \u1ed1ng ti\u00eau h\u00f3a v\u00e0 ni\u00eam m\u1ea1c mi\u1ec7ng). Khi truy\u1ec1n t\u0129nh m\u1ea1ch, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t kho\u1ea3ng 0,5-4 microgam\/ml; v\u1edbi li\u1ec1u duy tr\u00ec 400-600 microgam\/kg\/ng\u00e0y, n\u1ed3ng \u0111\u1ed9 huy\u1ebft t\u01b0\u01a1ng trung b\u00ecnh kho\u1ea3ng 0,5 microgam\/ml.<\/p>\n<p>Thu\u1ed1c c\u00f3 t\u1ec9 l\u1ec7 g\u1eafn k\u1ebft protein huy\u1ebft t\u01b0\u01a1ng cao v\u00e0 ph\u00e2n b\u1ed1 r\u1ed9ng v\u00e0o c\u00e1c t\u1ed5 ch\u1ee9c c\u01a1 th\u1ec3, d\u00f9 l\u01b0\u1ee3ng x\u00e2m nh\u1eadp v\u00e0o d\u1ecbch n\u00e3o t\u1ee7y kh\u00e1 h\u1ea1n ch\u1ebf.<\/p>\n<p>Th\u1eddi gian b\u00e1n th\u1ea3i (T1\/2) ban \u0111\u1ea7u kho\u1ea3ng 24 gi\u1edd, nh\u01b0ng c\u00f3 th\u1ec3 k\u00e9o d\u00e0i l\u00ean \u0111\u1ebfn 15 ng\u00e0y khi s\u1eed d\u1ee5ng d\u00e0i ng\u00e0y. Qu\u00e1 tr\u00ecnh th\u1ea3i tr\u1eeb qua th\u1eadn di\u1ec5n ra ch\u1eadm (ch\u1ec9 2 &#8211; 5% li\u1ec1u d\u00f9ng xu\u1ea5t hi\u1ec7n trong n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng c\u00f2n ho\u1ea1t t\u00ednh). Thu\u1ed1c v\u1eabn t\u00edch l\u0169y v\u00e0 t\u1ed3n t\u1ea1i trong n\u01b0\u1edbc ti\u1ec3u \u00edt nh\u1ea5t 7 tu\u1ea7n sau khi ng\u01b0ng \u0111i\u1ec1u tr\u1ecb, v\u1edbi t\u1ed5ng l\u01b0\u1ee3ng \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u trong 7 ng\u00e0y \u0111\u1ea7u \u0111\u1ea1t kho\u1ea3ng 40% li\u1ec1u truy\u1ec1n; \u0111\u00e2y \u0111\u01b0\u1ee3c xem l\u00e0 y\u1ebfu t\u1ed1 li\u00ean quan \u0111\u1ebfn \u0111\u1ed9c t\u00ednh tr\u00ean th\u1eadn. Ph\u01b0\u01a1ng ph\u00e1p l\u1ecdc m\u00e1u kh\u00f4ng lo\u1ea1i b\u1ecf \u0111\u01b0\u1ee3c Amphotericin B.<\/p>\n<h2>Thu\u1ed1c Amphot 50mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m n\u1ed9i t\u1ea1ng\/h\u1ec7 th\u1ed1ng: D\u00f9ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m n\u1ea5m to\u00e0n th\u00e2n, nhi\u1ec5m tr\u00f9ng huy\u1ebft do n\u1ea5m ho\u1eb7c vi\u00eam n\u1ed9i t\u00e2m m\u1ea1c do c\u00e1c ch\u1ee7ng nh\u1ea1y c\u1ea3m (nh\u01b0 <em>Candida spp., Blastomyces spp., Aspergillus spp., Cryptococcus spp., Coccidioides spp., Sporothrix spp<\/em>.).<\/p>\n<p>D\u1ef1 ph\u00f2ng nhi\u1ec5m n\u1ea5m: \u00c1p d\u1ee5ng cho b\u1ec7nh nh\u00e2n nhi\u1ec5m HIV, ng\u01b0\u1eddi ph\u1eabu thu\u1eadt gh\u00e9p t\u1ea1ng, b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb ung th\u01b0, ho\u1eb7c ng\u01b0\u1eddi b\u1ecb gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh k\u00e8m s\u1ed1t k\u00e9o d\u00e0i \u0111\u00e3 d\u00f9ng kh\u00e1ng sinh ph\u1ed5 r\u1ed9ng d\u00e0i ng\u00e0y.<\/p>\n<p>Thu\u1ed1c ch\u1ec9 \u0111\u01b0\u1ee3c ph\u00e9p s\u1eed d\u1ee5ng v\u00e0 theo d\u00f5i t\u1ea1i c\u00e1c c\u01a1 s\u1edf y t\u1ebf\/b\u1ec7nh vi\u1ec7n.<\/p>\n<figure id=\"attachment_161980\" aria-describedby=\"caption-attachment-161980\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-161980\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/08\/Amphot-50mg.jpg\" alt=\"Amphot 50mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/08\/Amphot-50mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/08\/Amphot-50mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/08\/Amphot-50mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/08\/Amphot-50mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/08\/Amphot-50mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-161980\" class=\"wp-caption-text\">Thu\u1ed1c Amphot 50mg ch\u1ee9a Amphotericin B, \u0111\u01b0\u1ee3c d\u00f9ng \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m n\u1eb7ng<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u th\u1eed: Tr\u01b0\u1edbc li\u1ec1u \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7u ti\u00ean, d\u00f9ng 1 mg Amphotericin B pha v\u1edbi 20 ml glucose 5%, truy\u1ec1n trong kho\u1ea3ng 20-30 ph\u00fat. Trong 2 gi\u1edd ti\u1ebfp theo, c\u1ea7n ki\u1ec3m tra m\u1ea1ch, huy\u1ebft \u00e1p, nhi\u1ec7t \u0111\u1ed9 v\u00e0 h\u00f4 h\u1ea5p c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh sau m\u1ed7i 30 ph\u00fat.<\/p>\n<p>Li\u1ec1u \u0111i\u1ec1u tr\u1ecb: C\u00f3 th\u1ec3 b\u1eaft \u0111\u1ea7u t\u1eeb m\u1ee9c 0,25 mg\/kg\/ng\u00e0y, sau \u0111\u00f3 \u0111i\u1ec1u ch\u1ec9nh t\u0103ng t\u1eebng b\u01b0\u1edbc n\u1ebfu thu\u1ed1c \u0111\u01b0\u1ee3c dung n\u1ea1p t\u1ed1t, t\u1ed1i \u0111a th\u00f4ng th\u01b0\u1eddng 1 mg\/kg\/ng\u00e0y. V\u1edbi tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m n\u1ea5m n\u1eb7ng, li\u1ec1u c\u00f3 th\u1ec3 l\u00ean \u0111\u1ebfn 1,5 mg\/kg\/ng\u00e0y ho\u1eb7c \u00e1p d\u1ee5ng l\u1ecbch d\u00f9ng thu\u1ed1c c\u00e1ch ng\u00e0y.<\/p>\n<p>Khi ng\u1eebng thu\u1ed1c tr\u00ean 7 ng\u00e0y: Kh\u00f4ng n\u00ean ti\u1ebfp t\u1ee5c ngay li\u1ec1u \u0111ang s\u1eed d\u1ee5ng tr\u01b0\u1edbc \u0111\u00f3 m\u00e0 c\u1ea7n kh\u1edfi \u0111\u1ea7u l\u1ea1i \u1edf m\u1ee9c 0,25 mg\/kg\/ng\u00e0y, r\u1ed3i t\u0103ng li\u1ec1u t\u1eeb t\u1eeb theo \u0111\u00e1p \u1ee9ng v\u00e0 kh\u1ea3 n\u0103ng dung n\u1ea1p.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>Pha Amphotericin B trong glucose 5% \u0111\u1ec3 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 kho\u1ea3ng 0,1 mg\/ml v\u00e0 truy\u1ec1n qua \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch. Th\u1eddi gian truy\u1ec1n th\u01b0\u1eddng k\u00e9o d\u00e0i 2-4 gi\u1edd, c\u00f3 th\u1ec3 k\u00e9o d\u00e0i \u0111\u1ebfn 6 gi\u1edd nh\u1eb1m h\u1ea1n ch\u1ebf nguy c\u01a1 \u0111\u1ed9c t\u00ednh.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Amphot 50mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi Amphotericin B ho\u1eb7c t\u00e1 d\u01b0\u1ee3c c\u00f3 trong<strong> b\u1ed9t pha ti\u00eam Amphot 50mg<\/strong><\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Do th\u1eddi gian \u0111i\u1ec1u tr\u1ecb k\u00e9o d\u00e0i v\u00e0 c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n ph\u1ea3n \u1ee9ng nghi\u00eam tr\u1ecdng, ng\u01b0\u1eddi b\u1ec7nh n\u00ean \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb n\u1ed9i tr\u00fa ho\u1eb7c theo d\u00f5i y t\u1ebf th\u01b0\u1eddng xuy\u00ean.<\/p>\n<p>N\u1ebfu ure ho\u1eb7c creatinin m\u00e1u t\u0103ng g\u1ea5p 2 l\u1ea7n m\u1ee9c b\u00ecnh th\u01b0\u1eddng, c\u1ea7n t\u1ea1m ng\u01b0ng Amphotericin B ho\u1eb7c \u0111i\u1ec1u ch\u1ec9nh gi\u1ea3m li\u1ec1u cho \u0111\u1ebfn khi ch\u1ee9c n\u0103ng th\u1eadn c\u1ea3i thi\u1ec7n.<\/p>\n<p>N\u00ean ki\u1ec3m tra c\u00f4ng th\u1ee9c m\u00e1u, kali v\u00e0 magnesi huy\u1ebft \u0111\u1ecbnh k\u1ef3 m\u1ed7i tu\u1ea7n trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Khi xu\u1ea5t hi\u1ec7n b\u1ea5t th\u01b0\u1eddng v\u1ec1 ch\u1ee9c n\u0103ng gan, \u0111\u1eb7c bi\u1ec7t t\u0103ng phosphatase ki\u1ec1m, bilirubin ho\u1eb7c enzym gan, c\u1ea7n ng\u1eebng thu\u1ed1c v\u00e0 \u0111\u00e1nh gi\u00e1 l\u1ea1i.<\/p>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi t\u1eebng \u0111\u01b0\u1ee3c chi\u1ebfu x\u1ea1 to\u00e0n th\u00e2n do nguy c\u01a1 xu\u1ea5t hi\u1ec7n b\u1ec7nh n\u00e3o tr\u1eafng.<\/p>\n<p>Kh\u00f4ng n\u00ean truy\u1ec1n Amphotericin B trong th\u1eddi gian d\u01b0\u1edbi 1 gi\u1edd, nh\u1ea5t l\u00e0 \u1edf ng\u01b0\u1eddi suy th\u1eadn, v\u00ec c\u00f3 th\u1ec3 l\u00e0m t\u0103ng kali m\u00e1u v\u00e0 g\u00e2y r\u1ed1i lo\u1ea1n nh\u1ecbp tim.<\/p>\n<p>H\u1ea1n ch\u1ebf ph\u1ed1i h\u1ee3p v\u1edbi corticosteroid n\u1ebfu kh\u00f4ng th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft, thu\u1ed1c ch\u1ed1ng ung th\u01b0 ho\u1eb7c c\u00e1c kh\u00e1ng sinh c\u00f3 \u0111\u1ed9c t\u00ednh tr\u00ean th\u1eadn \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 t\u1ed5n th\u01b0\u01a1ng th\u1eadn.<\/p>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng Amphotericin B \u1edf tr\u1ebb em c\u1ea7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n th\u1eadn tr\u1ecdng v\u00e0 theo d\u00f5i ph\u00f9 h\u1ee3p.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p, ADR &gt; 1\/100: S\u1ed1t k\u00e8m r\u00e9t run, \u0111au nh\u1ee9c \u0111\u1ea7u, \u0111au c\u01a1 ho\u1eb7c kh\u1edbp, thi\u1ebfu m\u00e1u \u0111\u1eb3ng s\u1eafc c\u00f3 kh\u1ea3 n\u0103ng h\u1ed3i ph\u1ee5c, bu\u1ed3n n\u00f4n, n\u00f4n \u00f3i, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, ch\u00e1n \u0103n, r\u1ed1i lo\u1ea1n c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i, h\u1ea1 kali m\u00e1u, gi\u1ea3m magnesi m\u00e1u, suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn, t\u0103ng n\u1ed3ng \u0111\u1ed9 creatinin v\u00e0 ur\u00ea trong m\u00e1u, \u0111au t\u1ea1i v\u1ecb tr\u00ed ti\u00eam, vi\u00eam t\u1eafc t\u0129nh m\u1ea1ch, k\u00edch \u1ee9ng da, ng\u1ee9a v\u00e0 n\u1ed5i ban.<\/p>\n<p>\u00cdt g\u1eb7p, 1\/1000 &lt; ADR &lt; 1\/100: V\u00f4 ni\u1ec7u, t\u1ed5n th\u01b0\u01a1ng th\u1eadn k\u00e9o d\u00e0i ho\u1eb7c kh\u00f4ng h\u1ed3i ph\u1ee5c, \u0111\u1eb7c bi\u1ec7t khi t\u1ed5ng l\u01b0\u1ee3ng Amphotericin B \u0111\u01b0\u1ee3c truy\u1ec1n v\u01b0\u1ee3t qu\u00e1 5 g.<\/p>\n<p>Hi\u1ebfm g\u1eb7p, ADR &lt; 1\/1000: Ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u, t\u0103ng b\u1ea1ch c\u1ea7u \u00e1i toan, t\u0103ng b\u1ea1ch c\u1ea7u, b\u1ea5t th\u01b0\u1eddng \u0111\u00f4ng m\u00e1u, t\u1ee5t huy\u1ebft \u00e1p, r\u1ed1i lo\u1ea1n nh\u1ecbp tim, rung th\u1ea5t, ng\u1eebng tim, ban d\u00e1t s\u1ea7n, t\u0103ng enzym transaminase, vi\u00eam d\u1ea1 d\u00e0y, vi\u00eam ru\u1ed9t, xu\u1ea5t huy\u1ebft \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, ch\u00f3ng m\u1eb7t, \u00f9 tai, gi\u1ea3m th\u00ednh l\u1ef1c, nh\u00ecn kh\u00f4ng r\u00f5, song th\u1ecb, b\u1ec7nh n\u00e3o tr\u1eafng, co gi\u1eadt, vi\u00eam d\u00e2y th\u1ea7n kinh ngo\u1ea1i bi\u00ean, b\u00ed ti\u1ec3u khi thu\u1ed1c \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o khoang t\u1ee7y s\u1ed1ng.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Ph\u1ed1i h\u1ee3p Amphotericin B v\u1edbi aminoglycosid, cyclosporin ho\u1eb7c c\u00e1c thu\u1ed1c c\u00f3 \u0111\u1ed9c t\u00ednh tr\u00ean th\u1eadn kh\u00e1c c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 t\u1ed5n th\u01b0\u01a1ng th\u1eadn.<\/p>\n<p>Corticosteroid c\u00f3 th\u1ec3 l\u00e0m t\u00ecnh tr\u1ea1ng h\u1ea1 kali m\u00e1u do Amphotericin B tr\u1edf n\u00ean nghi\u00eam tr\u1ecdng h\u01a1n.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 kali gi\u1ea3m do Amphotericin B c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh c\u1ee7a digitalis.<\/p>\n<p>Amphotericin B c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a flucytosin do th\u00fac \u0111\u1ea9y thu\u1ed1c \u0111i v\u00e0o t\u1ebf b\u00e0o v\u00e0 gi\u1ea3m qu\u00e1 tr\u00ecnh \u0111\u00e0o th\u1ea3i qua th\u1eadn.<\/p>\n<p>Khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi tubocurarin ho\u1eb7c suxamethonium, t\u00e1c d\u1ee5ng gi\u00e3n c\u01a1 c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 b\u1ecb k\u00e9o d\u00e0i ho\u1eb7c t\u0103ng l\u00ean.<\/p>\n<p>Kh\u00f4ng n\u00ean truy\u1ec1n Amphotericin B ngay sau truy\u1ec1n b\u1ea1ch c\u1ea7u v\u00ec c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n ph\u1ea3n \u1ee9ng c\u1ea5p t\u00ednh t\u1ea1i ph\u1ed5i.<\/p>\n<p>Kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng dung d\u1ecbch glucose hay NaCl \u0111\u1ec3 ho\u00e0n nguy\u00ean thu\u1ed1c d\u1ea1ng b\u1ed9t \u0111\u00f4ng kh\u00f4. \u0110\u1ed3ng th\u1eddi, kh\u00f4ng b\u1ed5 sung NaCl ho\u1eb7c c\u00e1c ch\u1ea5t \u0111i\u1ec7n gi\u1ea3i kh\u00e1c v\u00e0o dung d\u1ecbch Amphotericin B v\u00e0 tuy\u1ec7t \u0111\u1ed1i tr\u00e1nh pha chung v\u1edbi thu\u1ed1c kh\u00e1c.<\/p>\n<p>Ch\u1ec9 s\u1eed d\u1ee5ng dung m\u00f4i \u0111\u00e3 \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o \u0111\u1ec3 pha thu\u1ed1c. C\u00e1c lo\u1ea1i dung d\u1ecbch kh\u00f4ng ph\u00f9 h\u1ee3p ho\u1eb7c c\u00f3 ch\u1ee9a ch\u1ea5t b\u1ea3o qu\u1ea3n nh\u01b0 alcohol benzylic c\u00f3 th\u1ec3 l\u00e0m Amphotericin B k\u1ebft t\u1ee7a.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>M\u1ee9c \u0111\u1ed9 an to\u00e0n trong thai k\u1ef3 hi\u1ec7n ch\u01b0a c\u00f3 k\u1ebft lu\u1eadn \u0111\u1ea7y \u0111\u1ee7. Vi\u1ec7c can thi\u1ec7p \u0111i\u1ec1u tr\u1ecb ch\u1ec9 di\u1ec5n ra khi \u0111\u00e1nh gi\u00e1 th\u1ea5y hi\u1ec7u qu\u1ea3 mang l\u1ea1i l\u1edbn h\u01a1n nguy c\u01a1 c\u00f3 th\u1ec3 x\u1ea3y ra v\u1edbi thai nhi.<\/p>\n<p>Do hi\u1ec7n thi\u1ebfu d\u1eef li\u1ec7u v\u1ec1 kh\u1ea3 n\u0103ng \u0111\u00e0o th\u1ea3i c\u1ee7a ho\u1ea1t ch\u1ea5t v\u00e0o s\u1eefa m\u1eb9, vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c trong giai \u0111o\u1ea1n n\u00e0y \u0111\u00f2i h\u1ecfi s\u1ef1 c\u00e2n nh\u1eafc c\u1ea9n tr\u1ecdng gi\u1eefa l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb cho ng\u01b0\u1eddi m\u1eb9 v\u00e0 r\u1ee7i ro \u0111\u1ed1i v\u1edbi tr\u1ebb nh\u1ecf.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>S\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u Amphotericin B c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ebfn c\u1ed1 nguy hi\u1ec3m t\u00ednh m\u1ea1ng nh\u01b0 ng\u01b0ng tim ho\u1eb7c suy h\u00f4 h\u1ea5p.<\/p>\n<p>Khi c\u00f3 nghi ng\u1edd qu\u00e1 li\u1ec1u, c\u1ea7n ng\u01b0ng tr\u1ecb li\u1ec7u ngay l\u1eadp t\u1ee9c v\u00e0 ti\u1ebfn h\u00e0nh theo d\u00f5i ch\u1eb7t ch\u1ebd c\u00e1c ch\u1ec9 s\u1ed1 sinh t\u1ed3n c\u00f9ng ch\u1ee9c n\u0103ng c\u01a1 quan (bao g\u1ed3m h\u00f4 h\u1ea5p, tu\u1ea7n ho\u00e0n, gan, th\u1eadn, c\u00f4ng th\u1ee9c m\u00e1u v\u00e0 \u0111i\u1ec7n gi\u1ea3i \u0111\u1ed3) \u0111\u1ec3 tri\u1ec3n khai c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 ph\u00f9 h\u1ee3p<\/p>\n<p>Do ph\u01b0\u01a1ng ph\u00e1p l\u1ecdc m\u00e1u kh\u00f4ng gi\u00fap lo\u1ea1i b\u1ecf Amphotericin B kh\u1ecfi c\u01a1 th\u1ec3, ch\u1ec9 c\u00e2n nh\u1eafc t\u00e1i \u0111i\u1ec1u tr\u1ecb khi c\u00e1c ch\u1ec9 s\u1ed1 sinh l\u00fd c\u1ee7a b\u1ec7nh nh\u00e2n \u0111\u00e3 tr\u1edf l\u1ea1i m\u1ee9c \u1ed5n \u0111\u1ecbnh.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Amphot 50mg \u1edf t\u1ee7 l\u1ea1nh (2-8\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Dung d\u1ecbch g\u1ed1c (5mg\/ml) \u0111\u01b0\u1ee3c ph\u00e9p l\u01b0u gi\u1eef t\u1ed1i \u0111a 24 gi\u1edd trong t\u1ee7 l\u1ea1nh v\u00e0 tr\u00e1nh \u00e1nh s\u00e1ng, v\u1edbi \u0111i\u1ec1u ki\u1ec7n qu\u00e1 tr\u00ecnh pha ch\u1ebf ho\u00e0n to\u00e0n v\u00f4 tr\u00f9ng.<\/p>\n<p>C\u1ea7n s\u1eed d\u1ee5ng h\u1ebft trong v\u00f2ng 8 gi\u1edd k\u1ec3 t\u1eeb khi pha b\u1ed9t Amphot v\u1edbi dung m\u00f4i. Tr\u01b0\u1edbc khi th\u1ef1c hi\u1ec7n truy\u1ec1n, b\u1eaft bu\u1ed9c ki\u1ec3m tra c\u1ea3m quan: d\u1ecbch truy\u1ec1n ph\u1ea3i trong su\u1ed1t, ho\u00e0n to\u00e0n kh\u00f4ng xu\u1ea5t hi\u1ec7n v\u00f3n t\u1ee7a hay h\u1ea1t ti\u1ec3u ph\u00e2n l\u1ea1.<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Amphot 50mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Amphot 50mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>Thu\u1ed1c Amphot 50mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Amphot 50mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Amphot 50mg c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Akinosoglou K, Rigopoulos EA, Papageorgiou D, Schinas G, Polyzou E, Dimopoulou E, Gogos C, Dimopoulos G (2024). Amphotericin B in the Era of New Antifungals: Where Will It Stand? J Fungi (Basel). Truy c\u1eadp ng\u00e0y 21 th\u00e1ng 8 n\u0103m 2026 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38667949\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/38667949\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Amphot 50mg ch\u1ee9a ho\u1ea1t ch\u1ea5t Amphotericin B h\u00e0m l\u01b0\u1ee3ng 50mg, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m to\u00e0n th\u00e2n m\u1ee9c \u0111\u1ed9 n\u1eb7ng b\u1eb1ng con \u0111\u01b0\u1eddng ti\u00eam truy\u1ec1n t\u0129nh m\u1ea1ch.<\/p>\n","protected":false},"author":1,"featured_media":161981,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-161979","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/161979","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=161979"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/161981"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=161979"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=161979"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=161979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}