{"id":159196,"date":"2026-06-27T13:01:46","date_gmt":"2026-06-27T06:01:46","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=159196"},"modified":"2026-06-27T13:08:19","modified_gmt":"2026-06-27T06:08:19","slug":"samtrum-40mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/samtrum-40mg\/","title":{"rendered":"Samtrum 40mg"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Samtrum 40mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m TW 25 c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-35520-21<\/b><\/p>\n

Samtrum 40mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Th\u00e0nh ph\u1ea7n<\/h3>\n
Trong m\u1ed7i vi\u00ean Samtrum 40mg<\/b> c\u00f3 ch\u1ee9a:<\/p>\n
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Esomeprazol: 40mg<\/li>\n
T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n
D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang c\u1ee9ng ch\u1ee9a pellet bao tan trong ru\u1ed9t<\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: VD-35520-21<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n
H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Samtrum 40mg<\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n
Esomeprazol l\u00e0 m\u1ed9t base y\u1ebfu, \u0111\u01b0\u1ee3c t\u00edch l\u0169y t\u1ea1i m\u00f4i tr\u01b0\u1eddng acid c\u1ee7a \u1ed1ng ti\u1ec3u qu\u1ea3n ti\u1ebft \u1edf t\u1ebf b\u00e0o th\u00e0nh d\u1ea1 d\u00e0y v\u00e0 chuy\u1ec3n th\u00e0nh d\u1ea1ng ho\u1ea1t t\u00ednh. T\u1ea1i \u0111\u00e2y, thu\u1ed1c \u1ee9c ch\u1ebf h\u1ec7 enzym H\u207a\/K\u207a-ATPase, t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m c\u1ea3 ti\u1ebft acid n\u1ec1n v\u00e0 ti\u1ebft acid khi c\u00f3 k\u00edch th\u00edch.<\/p>\n
\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n
H\u1ea5p thu: B\u00e0o ch\u1ebf d\u1ea1ng h\u1ea1t bao tan trong ru\u1ed9t \u0111\u1ec3 tr\u00e1nh b\u1ecb acid d\u1ea1 d\u00e0y ph\u00e2n h\u1ee7y. Thu\u1ed1c h\u1ea5p thu nhanh, sau 1 – 2 gi\u1edd l\u00e0 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh. Sinh kh\u1ea3 d\u1ee5ng t\u0103ng t\u1eeb 64% l\u00ean 89% (v\u1edbi li\u1ec1u 40 mg) v\u00e0 t\u1eeb 50% l\u00ean 68% (v\u1edbi li\u1ec1u 20 mg) khi chuy\u1ec3n t\u1eeb li\u1ec1u \u0111\u01a1n sang li\u1ec1u l\u1eb7p l\u1ea1i. Th\u1ee9c \u0103n c\u00f3 l\u00e0m gi\u1ea3m v\u00e0 ch\u1eadm h\u1ea5p thu ho\u1ea1t ch\u1ea5t trong Samtrum nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 \u1ee9c ch\u1ebf acid.<\/p>\n
Ph\u00e2n b\u1ed1: Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 esomeprazol trong Samtrum \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh \u0111\u1ea1t kho\u1ea3ng 0,22 L\/kg th\u1ec3 tr\u1ecdng \u1edf ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh. Thu\u1ed1c c\u00f3 t\u1ef7 l\u1ec7 li\u00ean k\u1ebft r\u1ea5t cao v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, l\u00ean \u0111\u1ebfn 97%.<\/p>\n
Chuy\u1ec3n ho\u00e1: Chuy\u1ec3n h\u00f3a Esomeprazol ho\u00e0n to\u00e0n t\u1ea1i gan nh\u1edd h\u1ec7 Cytochrome P450. Trong \u0111\u00f3, enzym CYP2C19 ch\u1ecbu tr\u00e1ch nhi\u1ec7m ch\u00ednh (t\u1ea1o c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a hydroxy- v\u00e0 desmethyl), ph\u1ea7n c\u00f2n l\u1ea1i qua CYP3A4 \u0111\u1ec3 t\u1ea1o th\u00e0nh esomeprazol sulfon (ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh trong huy\u1ebft t\u01b0\u01a1ng).<\/p>\n
Th\u1ea3i tr\u1eeb: Sau 1,3 gi\u1edd khi d\u00f9ng li\u1ec1u l\u1eb7p l\u1ea1i thu\u1ed1c th\u1ea3i tr\u1eeb 1 n\u1eeda v\u00e0 kh\u00f4ng c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng t\u00edch l\u0169y thu\u1ed1c khi u\u1ed1ng 1 l\u1ea7n\/ng\u00e0y. T\u1ed5ng \u0111\u1ed9 thanh th\u1ea3i \u0111\u1ea1t 17 L\/gi\u1edd (li\u1ec1u \u0111\u01a1n) v\u00e0 gi\u1ea3m c\u00f2n 9 L\/gi\u1edd (li\u1ec1u l\u1eb7p l\u1ea1i). Kho\u1ea3ng 80% l\u01b0\u1ee3ng thu\u1ed1c \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a b\u1ea5t ho\u1ea1t, ph\u1ea7n c\u00f2n l\u1ea1i th\u1ea3i qua ph\u00e2n. L\u01b0\u1ee3ng thu\u1ed1c d\u1ea1ng nguy\u00ean v\u1eb9n trong n\u01b0\u1edbc ti\u1ec3u chi\u1ebfm ch\u01b0a t\u1edbi 1%.<\/p>\n
Thu\u1ed1c Samtrum \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n
\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh<\/b><\/p>\n
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B\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y – th\u1ef1c qu\u1ea3n (GERD):<\/li>\n<\/ul>\n
Ch\u1ec9 \u0111\u1ecbnh cho tr\u01b0\u1eddng h\u1ee3p th\u1ef1c qu\u1ea3n b\u1ecb t\u1ed5n th\u01b0\u01a1ng, vi\u00eam tr\u1ee3t do d\u1ecbch v\u1ecb tr\u00e0o ng\u01b0\u1ee3c.<\/p>\n
Ph\u00f2ng ng\u1eeba t\u00e1i ph\u00e1t th\u00f4ng qua \u0111i\u1ec1u tr\u1ecb duy tr\u00ec cho b\u1ec7nh nh\u00e2n \u0111\u00e3 h\u1ed3i ph\u1ee5c ni\u00eam m\u1ea1c th\u1ef1c qu\u1ea3n.<\/p>\n
Gi\u1ea3m thi\u1ec3u c\u00e1c bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng c\u1ee7a GERD tr\u00ean \u0111\u1ed1i t\u01b0\u1ee3ng kh\u00f4ng xu\u1ea5t hi\u1ec7n tri\u1ec7u ch\u1ee9ng vi\u00eam.<\/p>\n
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Ph\u1ed1i h\u1ee3p di\u1ec7t tr\u1eeb Helicobacter pylori (H. pylori): \u0110\u1ed3ng tr\u1ecb li\u1ec7u c\u00f9ng kh\u00e1ng sinh \u0111\u1ec3 x\u1eed l\u00fd \u1ed5 lo\u00e9t t\u00e1 tr\u00e0ng v\u00e0 ng\u0103n ch\u1eb7n nguy c\u01a1 t\u00e1i ph\u00e1t lo\u00e9t d\u1ea1 d\u00e0y – t\u00e1 tr\u00e0ng do nhi\u1ec5m khu\u1ea9n.<\/li>\n
B\u1ec7nh l\u00fd do d\u00f9ng thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID):<\/li>\n<\/ul>\n
Ch\u1eefa tr\u1ecb c\u00e1c v\u1ebft lo\u00e9t \u1edf d\u1ea1 d\u00e0y xu\u1ea5t hi\u1ec7n trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng NSAID.<\/p>\n
D\u1ef1 ph\u00f2ng t\u1ed5n th\u01b0\u01a1ng lo\u00e9t \u0111\u01b0\u1eddng ti\u00eau h\u00f3a \u1edf b\u1ec7nh nh\u00e2n thu\u1ed9c nh\u00f3m nguy c\u01a1 cao c\u00f3 ch\u1ec9 \u0111\u1ecbnh d\u00f9ng NSAID d\u00e0i h\u1ea1n.<\/p>\n
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H\u1ed9i ch\u1ee9ng Zollinger – Ellison: Ki\u1ec3m so\u00e1t v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00e1c t\u00ecnh tr\u1ea1ng t\u0103ng ti\u1ebft acid d\u1ea1 d\u00e0y do c\u0103n nguy\u00ean b\u1ec7nh l\u00fd.<\/li>\n<\/ul>\n
\u0110\u1ed1i v\u1edbi tr\u1ebb v\u1ecb th\u00e0nh ni\u00ean (T\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean)<\/b><\/p>\n
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B\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y – th\u1ef1c qu\u1ea3n (GERD):<\/li>\n<\/ul>\n
X\u1eed l\u00fd c\u00e1c v\u1ebft vi\u00eam x\u01b0\u1edbc t\u1ea1i th\u1ef1c qu\u1ea3n do h\u1ec7 qu\u1ea3 c\u1ee7a tr\u00e0o ng\u01b0\u1ee3c d\u1ecbch v\u1ecb.<\/p>\n
D\u00f9ng duy tr\u00ec sau giai \u0111o\u1ea1n c\u1ea5p nh\u1eb1m h\u1ea1n ch\u1ebf t\u1ed1i \u0111a nguy c\u01a1 t\u00e1i ph\u00e1t t\u1ed5n th\u01b0\u01a1ng.<\/p>\n
X\u1eed l\u00fd tri\u1ec7u ch\u1ee9ng c\u01a1 n\u0103ng cho ng\u01b0\u1eddi b\u1ec7nh GERD.<\/p>\n
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Lo\u00e9t t\u00e1 tr\u00e0ng do nhi\u1ec5m H. pylori: \u00c1p d\u1ee5ng trong ph\u00e1c \u0111\u1ed3 ph\u1ed1i h\u1ee3p kh\u00e1ng sinh \u0111\u1ec3 lo\u1ea1i b\u1ecf t\u00e1c nh\u00e2n vi khu\u1ea9n v\u00e0 ph\u1ee5c h\u1ed3i \u1ed5 lo\u00e9t.<\/li>\n<\/ul>\n
$\"Samtrum$
Samtrum 40mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y – t\u00e1 tr\u00e0ng<\/figcaption><\/figure>\n
Samtrum 40mg Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n
Li\u1ec1u d\u00f9ng<\/h3>\n
Ng\u01b0\u1eddi l\u1edbn<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n
Ch\u1ec9 \u0111\u1ecbnh<\/th>\n Li\u1ec1u d\u00f9ng<\/th>\n<\/tr>\n
Vi\u00eam x\u01b0\u1edbc th\u1ef1c qu\u1ea3n do GERD<\/td>\n 1 vi\u00ean Samtrum u\u1ed1ng 1 l\u1ea7n\/ng\u00e0y trong 4 tu\u1ea7n. N\u1ebfu t\u1ed5n th\u01b0\u01a1ng ch\u01b0a l\u00e0nh ho\u1eb7c tri\u1ec7u ch\u1ee9ng c\u00f2n k\u00e9o d\u00e0i, c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c th\u00eam 4 tu\u1ea7n.<\/td>\n<\/tr>\n
Duy tr\u00ec sau khi vi\u00eam th\u1ef1c qu\u1ea3n \u0111\u00e3 l\u00e0nh<\/td>\n \u0110\u1ed5i ch\u1ebf ph\u1ea9m kh\u00e1c c\u00f3 h\u00e0m l\u01b0\u1ee3ng 20mg<\/td>\n<\/tr>\n
\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng GERD kh\u00f4ng c\u00f3 vi\u00eam th\u1ef1c qu\u1ea3n<\/td>\n<\/tr>\n
Di\u1ec7t Helicobacter pylori<\/em>, \u0111i\u1ec1u tr\u1ecb v\u00e0 ph\u00f2ng t\u00e1i ph\u00e1t lo\u00e9t t\u00e1 tr\u00e0ng<\/td>\n<\/tr>\n
\u0110i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y do NSAID<\/td>\n<\/tr>\n
D\u1ef1 ph\u00f2ng lo\u00e9t do NSAID<\/td>\n<\/tr>\n
H\u1ed9i ch\u1ee9ng Zollinger-Ellison<\/td>\n Kh\u1edfi \u0111\u1ea7u 1 vi\u00ean Samtrum 40 x 2 l\u1ea7n\/ng\u00e0y, sau \u0111\u00f3 \u0111i\u1ec1u ch\u1ec9nh theo \u0111\u00e1p \u1ee9ng. \u0110a s\u1ed1 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t v\u1edbi t\u1ed5ng li\u1ec1u 80\u2013160 mg\/ng\u00e0y. N\u1ebfu d\u00f9ng tr\u00ean 80 mg\/ng\u00e0y n\u00ean chia l\u00e0m 2 l\u1ea7n.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Tr\u1ebb t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean<\/strong><\/p>\n\n\n\n\n\n\n\n
Ch\u1ec9 \u0111\u1ecbnh<\/th>\n Li\u1ec1u d\u00f9ng<\/th>\n<\/tr>\n
Vi\u00eam x\u01b0\u1edbc th\u1ef1c qu\u1ea3n do GERD<\/td>\n 1 vi\u00ean Samtrum\/ng\u00e0y 1 l\u1ea7n trong 4 tu\u1ea7n; c\u00f3 th\u1ec3 k\u00e9o d\u00e0i th\u00eam 4 tu\u1ea7n n\u1ebfu c\u1ea7n.<\/td>\n<\/tr>\n
Duy tr\u00ec sau \u0111i\u1ec1u tr\u1ecb<\/td>\n \u0110\u1ed5i ch\u1ebf ph\u1ea9m kh\u00e1c c\u00f3 h\u00e0m l\u01b0\u1ee3ng 20mg<\/td>\n<\/tr>\n
\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng GERD<\/td>\n<\/tr>\n
Lo\u00e9t t\u00e1 tr\u00e0ng do Helicobacter pylori<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u0110\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t<\/strong><\/p>\n\n\n\n\n\n\n\n
\u0110\u1ed1i t\u01b0\u1ee3ng<\/th>\n Li\u1ec1u d\u00f9ng<\/strong><\/th>\n<\/tr>\n
Tr\u1ebb d\u01b0\u1edbi 12 tu\u1ed5i<\/td>\n D\u1ea1ng vi\u00ean nang Samtrum kh\u00f4ng ph\u00f9 h\u1ee3p \u0111\u1ec3 s\u1eed d\u1ee5ng.<\/td>\n<\/tr>\n
Suy th\u1eadn<\/td>\n Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u. V\u1edbi suy th\u1eadn n\u1eb7ng, c\u1ea7n th\u1eadn tr\u1ecdng do c\u00f2n \u00edt d\u1eef li\u1ec7u l\u00e2m s\u00e0ng.<\/td>\n<\/tr>\n
Suy gan<\/td>\n Suy gan nh\u1eb9 ho\u1eb7c trung b\u00ecnh kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u. Suy gan n\u1eb7ng kh\u00f4ng n\u00ean d\u00f9ng qu\u00e1 20 mg esomeprazol m\u1ed7i ng\u00e0y.<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi cao tu\u1ed5i<\/td>\n Kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Thu\u1ed1c Samtrum 40mg u\u1ed1ng tr\u01b0\u1edbc hay sau \u0103n? C\u00e1ch d\u00f9ng<\/h3>\n
Vi\u00ean nang Samtrum<\/strong>\u00a0\u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng tr\u01b0\u1edbc \u0103n<\/p>\n
N\u1ebfu ng\u01b0\u1eddi b\u1ec7nh nu\u1ed1t kh\u00f3, c\u00f3 th\u1ec3 t\u00e1ch v\u1ecf nang v\u00e0 cho c\u00e1c vi h\u1ea1t v\u00e0o kho\u1ea3ng n\u1eeda c\u1ed1c n\u01b0\u1edbc l\u1ecdc kh\u00f4ng c\u00f3 gas. Khu\u1ea5y nh\u1eb9 \u0111\u1ec3 c\u00e1c vi h\u1ea1t ph\u00e2n t\u00e1n \u0111\u1ec1u r\u1ed3i u\u1ed1ng ngay, kh\u00f4ng \u0111\u1ec3 qu\u00e1 30 ph\u00fat sau khi pha. Sau khi u\u1ed1ng, th\u00eam m\u1ed9t l\u01b0\u1ee3ng n\u01b0\u1edbc t\u01b0\u01a1ng t\u1ef1 v\u00e0o c\u1ed1c, l\u1eafc nh\u1eb9 v\u00e0 u\u1ed1ng h\u1ebft ph\u1ea7n c\u00f2n l\u1ea1i \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o \u0111\u1ee7 li\u1ec1u. Ch\u1ec9 s\u1eed d\u1ee5ng n\u01b0\u1edbc kh\u00f4ng c\u00f3 gas \u0111\u1ec3 pha thu\u1ed1c v\u00e0 tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng l\u00e0m v\u1ee1 ho\u1eb7c nhai c\u00e1c vi h\u1ea1t.<\/p>\n
\u1ede nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng th\u1ec3 nu\u1ed1t, c\u00e1c vi h\u1ea1t sau khi ph\u00e2n t\u00e1n trong n\u01b0\u1edbc kh\u00f4ng c\u00f3 gas c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o d\u1ea1 d\u00e0y th\u00f4ng qua \u1ed1ng th\u00f4ng theo h\u01b0\u1edbng d\u1eabn c\u1ee7a nh\u00e2n vi\u00ean y t\u1ebf.<\/p>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Samtrum 40mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n
B\u1ec7nh nh\u00e2n t\u1eebng xu\u1ea5t hi\u1ec7n ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn v\u1edbi ho\u1ea1t ch\u1ea5t esomeprazol, c\u00e1c d\u1eabn xu\u1ea5t benzimidazol ho\u1eb7c b\u1ea5t c\u1ee9 t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u00f3 trong thu\u1ed1c.<\/p>\n
Tr\u00e1nh ph\u1ed1i h\u1ee3p Samtrum 40mg v\u1edbi nelfinavir v\u00ec \u0111\u00e2y l\u00e0 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
C\u1ea7n lo\u1ea1i tr\u1eeb nguy c\u01a1 b\u1ec7nh \u00e1c t\u00ednh khi c\u00f3 c\u00e1c d\u1ea5u hi\u1ec7u nh\u01b0 s\u1ee5t c\u00e2n kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n, n\u00f4n k\u00e9o d\u00e0i, kh\u00f3 nu\u1ed1t, n\u00f4n ra m\u00e1u ho\u1eb7c ph\u00e2n \u0111en, v\u00ec esomeprazol c\u00f3 th\u1ec3 che l\u1ea5p tri\u1ec7u ch\u1ee9ng v\u00e0 l\u00e0m ch\u1eadm ch\u1ea9n \u0111o\u00e1n.<\/p>\n
B\u1ec7nh nh\u00e2n d\u00f9ng thu\u1ed1c d\u00e0i ng\u00e0y (tr\u00ean 1 n\u0103m) n\u00ean \u0111\u01b0\u1ee3c theo d\u00f5i \u0111\u1ecbnh k\u1ef3.<\/p>\n
Ng\u01b0\u1eddi d\u00f9ng theo nhu c\u1ea7u c\u1ea7n li\u00ean h\u1ec7 b\u00e1c s\u0129 n\u1ebfu tri\u1ec7u ch\u1ee9ng thay \u0111\u1ed5i.<\/p>\n
Khi \u0111i\u1ec1u tr\u1ecb di\u1ec7t H. pylori<\/i>, c\u1ea7n l\u01b0u \u00fd t\u01b0\u01a1ng t\u00e1c trong ph\u00e1c \u0111\u1ed3 3 thu\u1ed1c, \u0111\u1eb7c bi\u1ec7t v\u1edbi clarithromycin v\u00e0 c\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a qua CYP3A4.<\/p>\n
C\u00f3 th\u1ec3 t\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n (Salmonella<\/i> v\u00e0 Campylobacter<\/i>) \u0111\u01b0\u1eddng ti\u00eau h\u00f3a<\/p>\n
<\/i>D\u00f9ng k\u00e9o d\u00e0i c\u00f3 th\u1ec3 gi\u1ea3m h\u1ea5p thu vitamin B12, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 thi\u1ebfu h\u1ee5t.<\/p>\n
Nguy c\u01a1 h\u1ea1 magnesi m\u00e1u khi d\u00f9ng d\u00e0i ng\u00e0y, c\u1ea7n theo d\u00f5i \u1edf b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb k\u00e9o d\u00e0i ho\u1eb7c d\u00f9ng k\u00e8m thu\u1ed1c nh\u01b0 digoxin, l\u1ee3i ti\u1ec3u.<\/p>\n
C\u00f3 th\u1ec3 l\u00e0m t\u0103ng nh\u1eb9 nguy c\u01a1 g\u00e3y x\u01b0\u01a1ng khi d\u00f9ng li\u1ec1u cao, d\u00e0i h\u1ea1n; n\u00ean b\u1ed5 sung calci v\u00e0 vitamin D n\u1ebfu c\u1ea7n.<\/p>\n
Hi\u1ebfm g\u1eb7p lupus ban \u0111\u1ecf b\u00e1n c\u1ea5p da (SCLE), c\u1ea7n ng\u1eebng thu\u1ed1c n\u1ebfu xu\u1ea5t hi\u1ec7n t\u1ed5n th\u01b0\u01a1ng da k\u00e8m \u0111au kh\u1edbp.<\/p>\n
Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng c\u00f9ng atazanavir, v\u00e0 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh ph\u1ed1i h\u1ee3p v\u1edbi nelfinavir.<\/p>\n
Esomeprazol c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn m\u1ed9t s\u1ed1 x\u00e9t nghi\u1ec7m (CgA), c\u1ea7n ng\u01b0ng thu\u1ed1c \u00edt nh\u1ea5t 5 ng\u00e0y tr\u01b0\u1edbc khi ki\u1ec3m tra n\u1ebfu c\u1ea7n.<\/p>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n
R\u1ed1i lo\u1ea1n c\u01a1 x\u01b0\u01a1ng v\u00e0 m\u00f4 li\u00ean k\u1ebft: T\u00ecnh tr\u1ea1ng g\u00e3y x\u01b0\u01a1ng c\u1ed5 tay, c\u1ed9t s\u1ed1ng ho\u1eb7c x\u01b0\u01a1ng h\u00f4ng l\u00e0 ph\u1ea3n \u1ee9ng ph\u1ee5 \u00edt khi x\u1ea3y ra; c\u00e1c bi\u1ec3u hi\u1ec7n \u0111au nh\u1ee9c c\u01a1, \u0111au m\u1ecfi kh\u1edbp thu\u1ed9c nh\u00f3m hi\u1ebfm g\u1eb7p; t\u00ecnh tr\u1ea1ng nh\u01b0\u1ee3c c\u01a1, y\u1ebfu c\u01a1 ch\u1ec9 xu\u1ea5t hi\u1ec7n v\u1edbi t\u1ea7n su\u1ea5t r\u1ea5t hi\u1ebfm g\u1eb7p.<\/p>\n
R\u1ed1i lo\u1ea1n th\u1eadn v\u00e0 ti\u1ebft ni\u1ec7u: Ghi nh\u1eadn t\u1ea7n su\u1ea5t r\u1ea5t hi\u1ebfm g\u1eb7p \u0111\u1ed1i v\u1edbi ch\u1ee9ng vi\u00eam th\u1eadn m\u00f4 k\u1ebd, c\u00f3 th\u1ec3 ti\u1ebfn tri\u1ec3n \u0111i k\u00e8m t\u00ecnh tr\u1ea1ng suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn tr\u00ean m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n.<\/p>\n
R\u1ed1i lo\u1ea1n h\u1ec7 sinh d\u1ee5c v\u00e0 tuy\u1ebfn v\u00fa: Ch\u1ee9ng s\u01b0ng \u0111au, n\u1eef h\u00f3a tuy\u1ebfn v\u00fa \u1edf nam gi\u1edbi l\u00e0 ph\u1ea3n \u1ee9ng ph\u1ee5 r\u1ea5t hi\u1ebfm khi x\u1ea3y ra.<\/p>\n
R\u1ed1i lo\u1ea1n to\u00e0n th\u00e2n v\u00e0 t\u1ea1i v\u1ecb tr\u00ed d\u00f9ng thu\u1ed1c: C\u00e1c bi\u1ec3u hi\u1ec7n kh\u00f4 mi\u1ec7ng, t\u0103ng ti\u1ebft m\u1ed3 h\u00f4i ho\u1eb7c n\u00f3ng b\u1eebng c\u01a1 th\u1ec3 thu\u1ed9c nh\u00f3m t\u00e1c d\u1ee5ng ph\u1ee5 hi\u1ebfm g\u1eb7p.<\/p>\n
T\u01b0\u01a1ng t\u00e1c<\/h3>\n
Thu\u1ed1c \u1ee9c ch\u1ebf protease: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh ph\u1ed1i h\u1ee3p v\u1edbi nelfinavir v\u00e0 kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng chung v\u1edbi atazanavir v\u00ec esomeprazol l\u00e0m t\u0103ng pH d\u1ea1 d\u00e0y v\u00e0 \u1ee9c ch\u1ebf enzym chuy\u1ec3n h\u00f3a, khi\u1ebfn n\u1ed3ng \u0111\u1ed9 c\u00e1c thu\u1ed1c n\u00e0y s\u1ee5t gi\u1ea3m nghi\u00eam tr\u1ecdng trong m\u00e1u; ng\u01b0\u1ee3c l\u1ea1i, thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00edch l\u0169y saquinavir nh\u01b0ng kh\u00f4ng g\u00e2y t\u00e1c \u0111\u1ed9ng l\u00ean darunavir, amprenavir hay lopinavir.<\/p>\n
Methotrexat: Vi\u1ec7c d\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng ti\u1ebft acid nh\u00f3m PPI c\u00f3 nguy c\u01a1 l\u00e0m gia t\u0103ng n\u1ed3ng \u0111\u1ed9 methotrexat trong huy\u1ebft thanh, do \u0111\u00f3 c\u1ea7n c\u00e2n nh\u1eafc t\u1ea1m th\u1eddi ng\u1eebng s\u1eed d\u1ee5ng esomeprazol khi b\u1ec7nh nh\u00e2n ph\u1ea3i \u0111i\u1ec1u tr\u1ecb b\u1eb1ng methotrexat li\u1ec1u cao.<\/p>\n
Tacrolimus: Ph\u1ed1i h\u1ee3p thu\u1ed1c l\u00e0m gia t\u0103ng n\u1ed3ng \u0111\u1ed9 tacrolimus trong m\u00e1u, \u0111\u00f2i h\u1ecfi ph\u1ea3i theo d\u00f5i s\u00e1t sao ch\u1ee9c n\u0103ng b\u00e0i ti\u1ebft c\u1ee7a th\u1eadn, ki\u1ec3m tra \u0111\u1ed9 thanh th\u1ea3i creatinin v\u00e0 n\u1ed3ng \u0111\u1ed9 thu\u1ed1c \u0111\u1ec3 ti\u1ebfn h\u00e0nh hi\u1ec7u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng tacrolimus k\u1ecbp th\u1eddi n\u1ebfu c\u1ea7n.<\/p>\n
Thu\u1ed1c h\u1ea5p thu ph\u1ee5 thu\u1ed9c pH: Do l\u00e0m gi\u1ea3m \u0111\u1ed9 acid d\u1ecbch v\u1ecb, esomeprazol g\u00e2y c\u1ea3n tr\u1edf v\u00e0 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng h\u1ea5p thu c\u1ee7a ketoconazol, itraconazol, erlotinib, \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 l\u00e0m t\u0103ng sinh kh\u1ea3 d\u1ee5ng c\u1ee7a digoxin d\u1eabn \u0111\u1ebfn nguy c\u01a1 \u0111\u1ed9c t\u00ednh, c\u1ea7n \u0111\u1eb7c bi\u1ec7t t\u0103ng c\u01b0\u1eddng gi\u00e1m s\u00e1t khi k\u00ea \u0111\u01a1n cho ng\u01b0\u1eddi cao tu\u1ed5i.<\/p>\n
Thu\u1ed1c chuy\u1ec3n h\u00f3a qua CYP2C19: Ho\u1ea1t t\u00ednh \u1ee9c ch\u1ebf enzym CYP2C19 c\u1ee7a esomeprazol l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a c\u00e1c thu\u1ed1c diazepam, citalopram, imipramin, clomipramin, phenytoin, voriconazol, cilostazol v\u00e0 cisaprid, \u0111\u00f2i h\u1ecfi ph\u1ea3i gi\u1ea3m li\u1ec1u c\u00e1c thu\u1ed1c n\u00e0y ho\u1eb7c theo d\u00f5i ch\u1eb7t ch\u1ebd bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng khi b\u1eaft \u0111\u1ea7u hay ng\u1eebng tr\u1ecb li\u1ec7u.<\/p>\n
Warfarin: M\u1eb7c d\u00f9 th\u1eddi gian \u0111\u00f4ng m\u00e1u th\u01b0\u1eddng gi\u1eef \u1edf m\u1ee9c \u1ed5n \u0111\u1ecbnh, m\u1ed9t s\u1ed1 \u00edt tr\u01b0\u1eddng h\u1ee3p th\u1ef1c t\u1ebf \u0111\u00e3 ghi nh\u1eadn ch\u1ec9 s\u1ed1 INR t\u0103ng cao r\u00f5 r\u1ec7t g\u00e2y nguy c\u01a1 xu\u1ea5t huy\u1ebft, v\u00ec v\u1eady c\u1ea7n th\u1ef1c hi\u1ec7n theo d\u00f5i c\u00e1c ch\u1ec9 s\u1ed1 \u0111\u00f4ng m\u00e1u khi b\u1ec7nh nh\u00e2n b\u1eaft \u0111\u1ea7u ho\u1eb7c k\u1ebft th\u00fac ph\u1ed1i h\u1ee3p thu\u1ed1c.<\/p>\n
Clopidogrel: Kh\u00f4ng khuy\u1ebfn kh\u00edch s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi do esomeprazol l\u00e0m gi\u1ea3m h\u00e0m l\u01b0\u1ee3ng ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh c\u1ee7a clopidogrel trong huy\u1ebft thanh, d\u1eabn \u0111\u1ebfn suy gi\u1ea3m hi\u1ec7u qu\u1ea3 \u1ee9c ch\u1ebf k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u v\u00e0 \u1ea3nh h\u01b0\u1edfng t\u1edbi \u0111\u00edch \u0111i\u1ec1u tr\u1ecb tim m\u1ea1ch.<\/p>\n
Thu\u1ed1c \u1ee9c ch\u1ebf CYP2C19 v\u00e0\/ho\u1eb7c CYP3A4: C\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf m\u1ea1nh nh\u01b0 clarithromycin hay voriconazol l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a v\u00e0 t\u0103ng n\u1ed3ng \u0111\u1ed9 esomeprazol trong m\u00e1u l\u00ean nhi\u1ec1u l\u1ea7n, d\u00f9 th\u00f4ng th\u01b0\u1eddng kh\u00f4ng c\u1ea7n \u0111\u1ed5i li\u1ec1u nh\u01b0ng v\u1eabn ph\u1ea3i l\u01b0u \u00fd hi\u1ec7u ch\u1ec9nh \u1edf ng\u01b0\u1eddi suy gan n\u1eb7ng ho\u1eb7c ph\u1ea3i d\u00f9ng thu\u1ed1c d\u00e0i ng\u00e0y.<\/p>\n
Thu\u1ed1c c\u1ea3m \u1ee9ng CYP2C19 v\u00e0\/ho\u1eb7c CYP3A4: Vi\u1ec7c d\u00f9ng ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c t\u00e1c nh\u00e2n c\u1ea3m \u1ee9ng enzym nh\u01b0 rifampicin ho\u1eb7c c\u00e1c ch\u1ebf ph\u1ea9m ch\u1ee9a c\u1ecf St. John’s s\u1ebd \u0111\u1ea9y nhanh t\u1ed1c \u0111\u1ed9 chuy\u1ec3n h\u00f3a thu\u1ed1c t\u1ea1i gan, g\u00e2y s\u1ee5t gi\u1ea3m m\u1ea1nh n\u1ed3ng \u0111\u1ed9 esomeprazol trong huy\u1ebft thanh v\u00e0 l\u00e0m gi\u1ea3m hi\u1ec7u l\u1ef1c \u0111i\u1ec1u tr\u1ecb.<\/p>\n
T\u01b0\u01a1ng k\u1ef5 c\u1ee7a thu\u1ed1c: Do ch\u01b0a c\u00f3 c\u00e1c kh\u1ea3o s\u00e1t v\u00e0 nghi\u00ean c\u1ee9u ch\u00ednh th\u1ee9c v\u1ec1 \u0111\u1eb7c t\u00ednh t\u01b0\u01a1ng k\u1ef5 c\u1ee7a ch\u1ebf ph\u1ea9m n\u00e0y, tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng t\u1ef1 \u00fd pha tr\u1ed9n hay d\u00f9ng chung thu\u1ed1c v\u1edbi c\u00e1c lo\u1ea1i d\u01b0\u1ee3c ch\u1ea5t kh\u00e1c trong c\u00f9ng m\u1ed9t dung m\u00f4i.<\/p>\n
L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n
D\u1eef li\u1ec7u l\u00e2m s\u00e0ng v\u1ec1 vi\u1ec7c d\u00f9ng esomeprazol \u1edf ng\u01b0\u1eddi mang thai c\u00f2n h\u1ea1n ch\u1ebf. Tuy nhi\u00ean, c\u00e1c nghi\u00ean c\u1ee9u d\u1ecbch t\u1ec5 h\u1ecdc di\u1ec7n r\u1ed9ng tr\u00ean h\u1ed7n h\u1ee3p racemic (omeprazol) v\u00e0 nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt \u0111\u1ec1u cho th\u1ea5y thu\u1ed1c kh\u00f4ng g\u00e2y d\u1ecb t\u1eadt ho\u1eb7c \u0111\u1ed9c t\u00ednh \u0111\u1ed1i v\u1edbi thai nhi v\u00e0 s\u1ef1 ph\u00e1t tri\u1ec3n sau sinh. D\u00f9 v\u1eady, v\u1eabn c\u1ea7n th\u1eadn tr\u1ecdng khi ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef c\u00f3 thai.<\/p>\n
Hi\u1ec7n ch\u01b0a r\u00f5 esomeprazol qua s\u1eefa m\u1eb9 hay kh\u00f4ng do thi\u1ebfu c\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng tr\u00ean \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y. V\u00ec v\u1eady, n\u1ebfu \u0111ang cho con b\u00fa kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng<\/p>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n
M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n nh\u01b0 ch\u00f3ng m\u1eb7t (hi\u1ebfm g\u1eb7p) ho\u1eb7c r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf m\u1ed9t s\u1ed1 ng\u01b0\u1eddi d\u00f9ng Samtrum, n\u00ean th\u1eadn tr\u1ecdng<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
Kinh nghi\u1ec7m l\u00e2m s\u00e0ng v\u1ec1 qu\u00e1 li\u1ec1u esomeprazol c\u00f2n h\u1ea1n ch\u1ebf. M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p d\u00f9ng li\u1ec1u r\u1ea5t cao (kho\u1ea3ng 280 mg) ghi nh\u1eadn ch\u1ee7 y\u1ebfu r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a v\u00e0 c\u1ea3m gi\u00e1c m\u1ec7t. Li\u1ec1u 2 vi\u00ean Samtrum 40 trong 1 l\u1ea7n u\u1ed1ng th\u01b0\u1eddng v\u1eabn dung n\u1ea1p t\u1ed1t.<\/p>\n
Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c Samtrum \u0111\u1eb7c hi\u1ec7u. Thu\u1ed1c g\u1eafn protein huy\u1ebft t\u01b0\u01a1ng m\u1ea1nh n\u00ean th\u1ea9m t\u00e1ch \u00edt hi\u1ec7u qu\u1ea3. Khi qu\u00e1 li\u1ec1u, ch\u1ee7 y\u1ebfu \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3 theo t\u00ecnh tr\u1ea1ng ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n
B\u1ea3o qu\u1ea3n<\/h3>\n
Gi\u1eef Samtrum 40 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (<30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n
Kh\u00f4ng \u0111\u1ec3 Samtrum 40 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n
Kh\u00f4ng s\u1eed d\u1ee5ng Samtrum 40 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n
Thu\u1ed1c Samtrum 40 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n
Samtrum 40mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Samtrum 40 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n
Tr\u01b0\u1eddng h\u1ee3p Samtrum 40 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Samtrum 40mg nh\u01b0:<\/p>\n
Esomeprazole Stada 40mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Esomeprazol 40mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Nh\u00e0 m\u00e1y Stada Vi\u1ec7t Nam, \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y-t\u00e1 tr\u00e0ng<\/p>\n
Yesom-40<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Esomeprazol 40mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Nh\u00e0 m\u00e1y Stada Vi\u1ec7t Nam, \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y-t\u00e1 tr\u00e0ng<\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n
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T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Samtrum 40mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 27 th\u00e1ng 6 n\u0103m 2026<\/li>\n
Hou M, Hu H, Jin C, Yu X (2020). Efficacy and Safety of Esomeprazole for the Treatment of Reflux Symptoms in Patients with Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis. Iran J Public Health. Truy c\u1eadp ng\u00e0y 27 th\u00e1ng 6 n\u0103m 2026 t\u1eeb: https:\/\/pubmed.ncbi.nlm.nih.gov\/34178733\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
Samtrum 40mg l\u00e0 vi\u00ean nang bao tan trong ru\u1ed9t gi\u00fap gi\u1ea3m ti\u1ebft acid d\u1ea1 d\u00e0y, h\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n, lo\u00e9t d\u1ea1 d\u00e0y \u2013 t\u00e1 tr\u00e0ng v\u00e0 c\u00e1c b\u1ec7nh li\u00ean quan t\u0103ng ti\u1ebft acid.<\/p>\n","protected":false},"author":1,"featured_media":159206,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-159196","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/159196","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=159196"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/159206"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=159196"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=159196"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=159196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Tr\u00ecnh b\u00e0y<\/h3>\nS\u0110K: VD-35520-21<\/p>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\nXu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\nH\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Samtrum 40mg<\/h2>\n

Samtrum 40mg Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n

Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: VD-35520-21<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n
H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n