{"id":158931,"date":"2026-06-19T11:43:08","date_gmt":"2026-06-19T04:43:08","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=158931"},"modified":"2026-06-19T11:44:57","modified_gmt":"2026-06-19T04:44:57","slug":"galfend-200mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/galfend-200mg\/","title":{"rendered":"Galfend 200mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Galfend 200mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n h\u00f3a-d\u01b0\u1ee3c ph\u1ea9m Mekophar c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110948224<\/b><\/p>\n<h2>Galfend 200mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i vi\u00ean <b>Galfend 200mg <\/b>c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Voriconazole: 200mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Tinh b\u1ed9t ng\u00f4, lactose monohydrate, croscarmellose sodium, colloidal silicon dioxide, magnesium stearate, hydroxypropyl methylcellulose 606, titanium dioxide v\u00e0 macrogol 6000.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110948224<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Galfend 200mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Voriconazole l\u00e0 thu\u1ed1c kh\u00e1ng n\u1ea5m nh\u00f3m triazole c\u00f3 c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf enzym 14-alpha-lanosterol demethylase c\u1ee7a h\u1ec7 cytochrome P450 \u1edf n\u1ea5m. Vi\u1ec7c phong b\u1ebf enzym n\u00e0y khi\u1ebfn qu\u00e1 tr\u00ecnh sinh t\u1ed5ng h\u1ee3p ergosterol b\u1ecb gi\u00e1n \u0111o\u1ea1n, \u0111\u1ed3ng th\u1eddi l\u00e0m c\u00e1c ti\u1ec1n ch\u1ea5t sterol methyl h\u00f3a t\u00edch t\u1ee5 trong t\u1ebf b\u00e0o. Nh\u1eefng thay \u0111\u1ed5i n\u00e0y l\u00e0m r\u1ed1i lo\u1ea1n c\u1ea5u tr\u00fac c\u0169ng nh\u01b0 ch\u1ee9c n\u0103ng c\u1ee7a m\u00e0ng t\u1ebf b\u00e0o n\u1ea5m, g\u00f3p ph\u1ea7n \u1ee9c ch\u1ebf s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh. Ho\u1ea1t ch\u1ea5t cho th\u1ea5y t\u00ednh ch\u1ecdn l\u1ecdc cao \u0111\u1ed1i v\u1edbi enzym c\u1ee7a n\u1ea5m h\u01a1n so v\u1edbi enzym cytochrome P450 \u1edf \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Thu\u1ed1c \u0111\u01b0\u1ee3c dung n\u1ea1p r\u1ea5t nhanh qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 \u0111\u1ea1t Cmax (n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a) trong m\u00e1u sau kho\u1ea3ng 1h \u0111\u1ebfn 2h v\u1edbi sinh kh\u1ea3 d\u1ee5ng ~ 96%. N\u1ebfu u\u1ed1ng thu\u1ed1c c\u00f9ng c\u00e1c m\u00f3n \u0103n ch\u1ee9a h\u00e0m l\u01b0\u1ee3ng ch\u1ea5t b\u00e9o cao, ch\u1ec9 s\u1ed1 Cmax v\u00e0 di\u1ec7n t\u00edch d\u01b0\u1edbi \u0111\u01b0\u1eddng cong (AUC) gi\u1ea3m l\u1ea7n l\u01b0\u1ee3t l\u00e0 34% v\u00e0 24%. S\u1ef1 thay \u0111\u1ed5i \u0111\u1ed9 pH trong d\u1ea1 d\u00e0y kh\u00f4ng l\u00e0m \u1ea3nh h\u01b0\u1edfng t\u1edbi m\u1ee9c \u0111\u1ed9 h\u1ea5p thu.<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c th\u00e2m nh\u1eadp t\u1ed1t v\u00e0o c\u00e1c m\u00f4 v\u1edbi th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 \u1edf tr\u1ea1ng th\u00e1i c\u00e2n b\u1eb1ng duy tr\u00ec kho\u1ea3ng 4,6 l\u00edt\/kg v\u00e0 t\u1ef7 l\u1ec7 g\u1eafn k\u1ebft v\u1edbi protein trong huy\u1ebft t\u01b0\u01a1ng l\u00e0 58%. Ngo\u00e0i ra, s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a ho\u1ea1t ch\u1ea5t c\u00f2n \u0111\u01b0\u1ee3c ghi nh\u1eadn trong d\u1ecbch n\u00e3o t\u1ee7y \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n tham gia ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u m\u1edf r\u1ed9ng.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a di\u1ec5n ra t\u1ea1i gan th\u00f4ng qua c\u00e1c isoenzyme c\u1ee7a cytochrome P450 bao g\u1ed3m CYP2C19, CYP2C9 v\u00e0 CYP3A4. T\u1ed1c \u0111\u1ed9 chuy\u1ec3n h\u00f3a c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t r\u1ea5t l\u1edbn t\u00f9y thu\u1ed9c v\u00e0o c\u01a1 \u0111\u1ecba t\u1eebng c\u00e1 th\u1ec3.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Con \u0111\u01b0\u1eddng \u0111\u00e0o th\u1ea3i ch\u00ednh l\u00e0 qua gan, l\u01b0\u1ee3ng thu\u1ed1c gi\u1eef nguy\u00ean v\u1eb9n xu\u1ea5t hi\u1ec7n trong n\u01b0\u1edbc ti\u1ec3u chi\u1ebfm ch\u01b0a \u0111\u1ea7y 2%. T\u1ed5ng l\u01b0\u1ee3ng ch\u1ea5t c\u00f3 \u0111\u00e1nh d\u1ea5u ph\u00f3ng x\u1ea1 \u0111\u01b0\u1ee3c b\u00e0i xu\u1ea5t qua n\u01b0\u1edbc ti\u1ec3u \u0111\u1ea1t kho\u1ea3ng 80% (v\u1edbi d\u1ea1ng truy\u1ec1n) v\u00e0 83% (v\u1edbi d\u1ea1ng u\u1ed1ng), ph\u1ea7n l\u1edbn (&gt; 94%) \u0111\u01b0\u1ee3c th\u1ea3i s\u1ea1ch trong v\u00f2ng 96 gi\u1edd \u0111\u1ea7u. Th\u1eddi gian b\u00e1n th\u1ea3i (t1\/2) c\u1ee7a li\u1ec1u u\u1ed1ng 200mg kho\u1ea3ng 6 ti\u1ebfng. Do c\u00f3 \u0111\u1eb7c t\u00ednh d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc kh\u00f4ng tuy\u1ebfn t\u00ednh n\u00ean th\u1eddi gian b\u00e1n th\u1ea3i kh\u00f4ng d\u00f9ng \u0111\u1ec3 d\u1ef1 \u0111o\u00e1n ch\u00ednh x\u00e1c l\u01b0\u1ee3ng t\u00edch t\u1ee5 hay t\u1ed1c \u0111\u1ed9 lo\u1ea1i th\u1ea3i c\u1ee7a thu\u1ed1c.<\/p>\n<h2>Thu\u1ed1c Galfend 200mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb nh\u1ecf t\u1eeb 2 tu\u1ed5i tr\u1edf l\u00ean \u0111\u1ed1i v\u1edbi c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m n\u1ea5m ti\u1ebfn tri\u1ec3n:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m Aspergillus th\u1ec3 x\u00e2m l\u1ea5n.<\/li>\n<li>Ng\u01b0\u1eddi b\u1ecb nhi\u1ec5m Candida huy\u1ebft (\u00e1p d\u1ee5ng cho \u0111\u1ed1i t\u01b0\u1ee3ng kh\u00f4ng b\u1ecb s\u1ee5t gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh).<\/li>\n<li>C\u00e1c ca nhi\u1ec5m Candida x\u00e2m l\u1ea5n th\u1ec3 n\u1eb7ng \u0111\u00e3 xu\u1ea5t hi\u1ec7n t\u00ecnh tr\u1ea1ng kh\u00e1ng thu\u1ed1c fluconazole (bao g\u1ed3m c\u1ea3 ch\u1ee7ng C.krusei).<\/li>\n<li>Tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m c\u00e1c ch\u1ee7ng n\u1ea5m Fusarium spp. v\u00e0 Scedosporium spp. m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng.<\/li>\n<li>S\u1eed d\u1ee5ng \u0111\u1ec3 ph\u00f2ng ng\u1eeba c\u00e1c \u0111\u1ee3t nhi\u1ec5m n\u1ea5m x\u00e2m l\u1ea5n cho nh\u1eefng ng\u01b0\u1eddi th\u1ef1c hi\u1ec7n c\u1ea5y gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c t\u1ea1o m\u00e1u thu\u1ed9c nh\u00f3m c\u00f3 nguy c\u01a1 cao.<\/li>\n<\/ul>\n<figure id=\"attachment_158932\" aria-describedby=\"caption-attachment-158932\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-158932\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/06\/Galfend-200mg.jpg\" alt=\"Galfend 200mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/06\/Galfend-200mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/06\/Galfend-200mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/06\/Galfend-200mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/06\/Galfend-200mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/06\/Galfend-200mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-158932\" class=\"wp-caption-text\">Thu\u1ed1c Galfend 200mg \u0111i\u1ec1u tr\u1ecb c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m n\u1ea5m x\u00e2m l\u1ea5n<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p><b>Ng\u01b0\u1eddi l\u1edbn <\/b>(\u00e1p d\u1ee5ng cho b\u1ec7nh nh\u00e2n t\u1eeb 15 tu\u1ed5i) <b>:<\/b> \u0110i\u1ec1u tr\u1ecb th\u01b0\u1eddng \u0111\u01b0\u1ee3c b\u1eaft \u0111\u1ea7u b\u1eb1ng voriconazole \u0111\u01b0\u1eddng u\u1ed1ng ho\u1eb7c truy\u1ec1n t\u0129nh m\u1ea1ch v\u1edbi li\u1ec1u kh\u1edfi \u0111\u1ea7u nh\u1eb1m nhanh ch\u00f3ng \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 thu\u1ed1c mong mu\u1ed1n. Khi t\u00ecnh tr\u1ea1ng l\u00e2m s\u00e0ng cho ph\u00e9p, c\u00f3 th\u1ec3 chuy\u1ec3n \u0111\u1ed5i gi\u1eefa hai \u0111\u01b0\u1eddng d\u00f9ng.<\/p>\n<ul>\n<li><b>Li\u1ec1u t\u1ea5n c\u00f4ng (24 gi\u1edd \u0111\u1ea7u):<\/b> Ng\u01b0\u1eddi b\u1ec7nh t\u1eeb 40kg tr\u1edf l\u00ean c\u1ee9 12 gi\u1edd d\u00f9ng 400mg, ng\u01b0\u1eddi d\u01b0\u1edbi 40kg c\u1ee9 12 gi\u1edd d\u00f9ng 200mg<\/li>\n<li><b>Li\u1ec1u duy tr\u00ec:<\/b> Ng\u01b0\u1eddi t\u1eeb 40kg tr\u1edf l\u00ean d\u00f9ng 200mg\/l\u1ea7n, ng\u00e0y 2 l\u1ea7n; ng\u01b0\u1eddi d\u01b0\u1edbi 40kg d\u00f9ng 100mg\/l\u1ea7n, ng\u00e0y 2 l\u1ea7n.<\/li>\n<li><b>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u:<\/b> N\u1ebfu hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb ch\u01b0a \u0111\u00e1p \u1ee9ng, c\u00f3 th\u1ec3 t\u0103ng l\u00ean 300mg x 2 l\u1ea7n\/ng\u00e0y \u1edf ng\u01b0\u1eddi t\u1eeb 40kg tr\u1edf l\u00ean ho\u1eb7c 150mg x 2 l\u1ea7n\/ng\u00e0y \u1edf ng\u01b0\u1eddi d\u01b0\u1edbi 40kg. N\u1ebfu ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng dung n\u1ea1p thu\u1ed1c, gi\u1ea3m t\u1eebng b\u1eadc 50mg cho \u0111\u1ebfn khi \u0111\u1ea1t li\u1ec1u 200mg x 2 l\u1ea7n\/ng\u00e0y ho\u1eb7c 100mg x 2 l\u1ea7n\/ng\u00e0y \u1edf b\u1ec7nh nh\u00e2n d\u01b0\u1edbi 40kg.<\/li>\n<li><b>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb:<\/b> N\u00ean duy tr\u00ec trong kho\u1ea3ng th\u1eddi gian ng\u1eafn nh\u1ea5t v\u1eabn b\u1ea3o \u0111\u1ea3m hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb. Khi c\u1ea7n s\u1eed d\u1ee5ng tr\u00ean 180 ng\u00e0y (6 th\u00e1ng), b\u00e1c s\u0129 s\u1ebd c\u00e2n nh\u1eafc k\u1ef9 gi\u1eefa l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 tr\u01b0\u1edbc khi ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb.<\/li>\n<\/ul>\n<p><b>Tr\u1ebb t\u1eeb 2 \u0111\u1ebfn d\u01b0\u1edbi 12 tu\u1ed5i v\u00e0 thanh thi\u1ebfu ni\u00ean t\u1eeb 12\u201314 tu\u1ed5i c\u00f3 c\u00e2n n\u1eb7ng d\u01b0\u1edbi 50kg:<\/b> Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng li\u1ec1u t\u1ea5n c\u00f4ng.<\/p>\n<ul>\n<li><b>Li\u1ec1u duy tr\u00ec:<\/b> 9mg\/kg\/l\u1ea7n, ng\u00e0y 2 l\u1ea7n, t\u1ed1i \u0111a 350mg m\u1ed7i l\u1ea7n.<\/li>\n<li><b>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u:<\/b> N\u1ebfu \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb ch\u01b0a \u0111\u1ea1t, c\u00f3 th\u1ec3 t\u0103ng t\u1eebng 1mg\/kg m\u1ed7i l\u1ea7n ho\u1eb7c t\u0103ng t\u1eebng 50mg khi \u0111\u00e3 s\u1eed d\u1ee5ng m\u1ee9c t\u1ed1i \u0111a. Tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng dung n\u1ea1p, gi\u1ea3m t\u1eebng 1mg\/kg ho\u1eb7c gi\u1ea3m t\u1eebng 50mg n\u1ebfu \u0111ang d\u00f9ng li\u1ec1u t\u1ed1i \u0111a. Hi\u1ec7n ch\u01b0a c\u00f3 d\u1eef li\u1ec7u v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng voriconazole \u1edf tr\u1ebb trong nh\u00f3m tu\u1ed5i n\u00e0y b\u1ecb suy gan ho\u1eb7c suy th\u1eadn.<\/li>\n<li><b>Thanh thi\u1ebfu ni\u00ean:<\/b> Ng\u01b0\u1eddi t\u1eeb 12\u201314 tu\u1ed5i c\u00f3 c\u00e2n n\u1eb7ng t\u1eeb 50kg tr\u1edf l\u00ean ho\u1eb7c t\u1eeb 15\u201317 tu\u1ed5i \u00e1p d\u1ee5ng ph\u00e1c \u0111\u1ed3 li\u1ec1u gi\u1ed1ng ng\u01b0\u1eddi l\u1edbn.<\/li>\n<\/ul>\n<p><b>D\u1ef1 ph\u00f2ng nhi\u1ec5m n\u1ea5m:<\/b> N\u00ean b\u1eaft \u0111\u1ea7u t\u1eeb ng\u00e0y ti\u1ebfn h\u00e0nh gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c t\u1ea1o m\u00e1u. Th\u1eddi gian d\u1ef1 ph\u00f2ng th\u00f4ng th\u01b0\u1eddng kh\u00f4ng qu\u00e1 100 ng\u00e0y. Ch\u1ec9 xem x\u00e9t k\u00e9o d\u00e0i \u0111\u1ebfn t\u1ed1i \u0111a 180 ng\u00e0y sau gh\u00e9p n\u1ebfu ng\u01b0\u1eddi b\u1ec7nh v\u1eabn c\u00f2n t\u00ecnh tr\u1ea1ng \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch ho\u1eb7c m\u1eafc b\u1ec7nh m\u1ea3nh gh\u00e9p ch\u1ed1ng ch\u1ee7 (GVHD). Li\u1ec1u d\u1ef1 ph\u00f2ng \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 li\u1ec1u \u0111i\u1ec1u tr\u1ecb c\u1ee7a t\u1eebng nh\u00f3m tu\u1ed5i.<\/p>\n<p><b>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u khi ph\u1ed1i h\u1ee3p thu\u1ed1c:<\/b> Ph\u1ed1i h\u1ee3p v\u1edbi phenytoin c\u1ea7n t\u0103ng li\u1ec1u voriconazole \u0111\u01b0\u1eddng u\u1ed1ng l\u00ean 400mg x 2 l\u1ea7n\/ng\u00e0y (200mg x 2 l\u1ea7n\/ng\u00e0y \u1edf b\u1ec7nh nh\u00e2n d\u01b0\u1edbi 40kg). N\u1ebfu b\u1eaft bu\u1ed9c d\u00f9ng c\u00f9ng rifabutin, t\u0103ng li\u1ec1u voriconazole l\u00ean 350mg x 2 l\u1ea7n\/ng\u00e0y (200mg x 2 l\u1ea7n\/ng\u00e0y \u1edf b\u1ec7nh nh\u00e2n d\u01b0\u1edbi 40kg). Khi ph\u1ed1i h\u1ee3p v\u1edbi efavirenz, t\u0103ng voriconazole l\u00ean 400mg m\u1ed7i 12 gi\u1edd v\u00e0 gi\u1ea3m efavirenz xu\u1ed1ng 300mg\/ng\u00e0y; sau khi ng\u1eebng voriconazole c\u1ea7n d\u00f9ng l\u1ea1i li\u1ec1u efavirenz ban \u0111\u1ea7u.<\/p>\n<p><b>Ng\u01b0\u1eddi cao tu\u1ed5i:<\/b> d\u00f9ng Galfend t\u01b0\u01a1ng t\u1ef1 ng\u01b0\u1eddi l\u1edbn m\u00e0 kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u<\/p>\n<p><b>B\u1ec7nh nh\u00e2n suy th\u1eadn:<\/b> Voriconazole d\u1ea1ng u\u1ed1ng kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn t\u1eeb nh\u1eb9 \u0111\u1ebfn n\u1eb7ng. Th\u1ea9m t\u00e1ch m\u00e1u kh\u00f4ng lo\u1ea1i b\u1ecf l\u01b0\u1ee3ng thu\u1ed1c \u0111\u1ee7 l\u1edbn \u0111\u1ec3 ph\u1ea3i thay \u0111\u1ed5i ch\u1ebf \u0111\u1ed9 li\u1ec1u.<\/p>\n<p><b>B\u1ec7nh nh\u00e2n suy gan:<\/b> Ng\u01b0\u1eddi m\u1eafc x\u01a1 gan Child-Pugh A ho\u1eb7c B s\u1eed d\u1ee5ng li\u1ec1u t\u1ea5n c\u00f4ng nh\u01b0 th\u00f4ng th\u01b0\u1eddng, sau \u0111\u00f3 gi\u1ea3m c\u00f2n m\u1ed9t n\u1eeda li\u1ec1u duy tr\u00ec. Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng \u1edf b\u1ec7nh nh\u00e2n Child-Pugh C. \u0110\u1ed1i v\u1edbi tr\u01b0\u1eddng h\u1ee3p suy gan n\u1eb7ng ho\u1eb7c c\u00f3 c\u00e1c ch\u1ec9 s\u1ed1 ch\u1ee9c n\u0103ng gan t\u0103ng cao, ch\u1ec9 n\u00ean \u0111i\u1ec1u tr\u1ecb khi l\u1ee3i \u00edch d\u1ef1 ki\u1ebfn v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd trong su\u1ed1t qu\u00e1 tr\u00ecnh d\u00f9ng thu\u1ed1c.<\/p>\n<p><b>Tr\u1ebb d\u01b0\u1edbi 2 tu\u1ed5i:<\/b> \u0110\u1ebfn nay v\u1eabn ch\u01b0a x\u00e1c l\u1eadp \u0111\u01b0\u1ee3c t\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a Galfend 200mg \u1edf nh\u00f3m tu\u1ed5i n\u00e0y<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb v\u1ecb th\u00e0nh ni\u00ean t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean: Nu\u1ed1t <strong>vi\u00ean n\u00e9n Galfend 200mg<\/strong> c\u00f9ng v\u1edbi n\u01b0\u1edbc, th\u1eddi \u0111i\u1ec3m d\u00f9ng l\u00e0 \u00edt nh\u1ea5t 1 ti\u1ebfng tr\u01b0\u1edbc khi \u0103n ho\u1eb7c ph\u1ea3i \u0111\u1ee3i 1 ti\u1ebfng sau khi \u0103n xong.<\/p>\n<p>Tr\u1ebb em c\u00f3 \u0111\u1ed9 tu\u1ed5i t\u1eeb 2 \u0111\u1ebfn d\u01b0\u1edbi 12 tu\u1ed5i: \u0110\u1ed1i v\u1edbi nh\u00f3m tu\u1ed5i n\u00e0y, khuy\u1ebfn ngh\u1ecb n\u00ean \u01b0u ti\u00ean s\u1eed d\u1ee5ng c\u00e1c d\u1ea1ng ch\u1ebf ph\u1ea9m b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng h\u1ed7n d\u1ecbch d\u1ecbch u\u1ed1ng (thay v\u00ec vi\u00ean n\u00e9n bao phim).<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Galfend 200mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi Voriconazole ho\u1eb7c b\u1ea5t c\u1ee9 t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u00f3 trong Galfend 200mg<\/p>\n<p>D\u00f9ng chung v\u1edbi terfenadine, astemizole, cisapride, pimozide, quinidine (nguy c\u01a1 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u00e1c thu\u1ed1c n\u00e0y trong m\u00e1u d\u1eabn \u0111\u1ebfn k\u00e9o d\u00e0i kho\u1ea3ng QT v\u00e0 g\u00e2y xo\u1eafn \u0111\u1ec9nh).<\/p>\n<p>Kh\u00f4ng ph\u1ed1i h\u1ee3p c\u00f9ng c\u00e1c thu\u1ed1c: rifampicin, carbamazepine, phenobarbital do ch\u00fang l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Voriconazole trong huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<p>D\u00f9ng c\u00f9ng efavirenz v\u1edbi li\u1ec1u t\u1eeb 400mg\/ng\u00e0y tr\u1edf l\u00ean (efavirenz l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng Voriconazole, ng\u01b0\u1ee3c l\u1ea1i Voriconazole l\u1ea1i l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 efavirenz trong m\u00e1u).<\/p>\n<p>Kh\u00f4ng k\u1ebft h\u1ee3p v\u1edbi ritonavir li\u1ec1u cao (\u2265 400mg, ng\u00e0y 2 l\u1ea7n) do ritonavir l\u00e0m n\u1ed3ng \u0111\u1ed9 Voriconazole gi\u1ea3m<\/p>\n<p>D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c alkaloid c\u1ee7a n\u1ea5m c\u1ef1a g\u00e0 (nh\u01b0 ergotamine, dihydroergotamine) v\u00ec d\u1ec5 g\u00e2y \u0111\u1ed9c t\u00ednh ergotin<\/p>\n<p>S\u1eed d\u1ee5ng chung v\u1edbi sirolimus (Voriconazole l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 sirolimus t\u0103ng trong m\u00e1u).<\/p>\n<p>D\u00f9ng chung v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n t\u1eeb c\u00e2y c\u1ecf Th\u00e1nh John (St. John&#8217;s Wort).<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Tr\u01b0\u1edbc v\u00e0 trong giai \u0111o\u1ea1n \u0111i\u1ec1u tr\u1ecb, c\u1ea7n ti\u1ebfn h\u00e0nh ki\u1ec3m tra v\u00e0 kh\u1eafc ph\u1ee5c k\u1ecbp th\u1eddi c\u00e1c t\u00ecnh tr\u1ea1ng r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i n\u1ebfu c\u00f3 (nh\u01b0 thi\u1ebfu h\u1ee5t kali, magnesi hay calci trong m\u00e1u).<\/p>\n<p>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Galfend cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng n\u1ea5m nh\u00f3m azole.<\/p>\n<p>\u0110\u00e1nh gi\u00e1 nguy c\u01a1 r\u1ed1i lo\u1ea1n nh\u1ecbp tim tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb \u1edf b\u1ec7nh nh\u00e2n c\u00f3 h\u1ed9i ch\u1ee9ng QT k\u00e9o d\u00e0i, suy tim, b\u1ec7nh c\u01a1 tim, nh\u1ecbp tim ch\u1eadm ho\u1eb7c ti\u1ec1n s\u1eed lo\u1ea1n nh\u1ecbp.<\/p>\n<p>Ki\u1ec3m tra v\u00e0 \u0111i\u1ec1u ch\u1ec9nh c\u00e1c r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i (kali, magnesi, calci) tr\u01b0\u1edbc v\u00e0 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb n\u1ebfu c\u1ea7n.<\/p>\n<p>Theo d\u00f5i ch\u1ee9c n\u0103ng gan tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb, h\u00e0ng tu\u1ea7n trong th\u00e1ng \u0111\u1ea7u v\u00e0 \u0111\u1ecbnh k\u1ef3 trong th\u1eddi gian d\u00f9ng thu\u1ed1c; ng\u1eebng thu\u1ed1c n\u1ebfu men gan t\u0103ng \u0111\u00e1ng k\u1ec3 khi l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb kh\u00f4ng c\u00f2n v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1.<\/p>\n<p>H\u1ea1n ch\u1ebf ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp v\u1edbi \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi, m\u1eb7c qu\u1ea7n \u00e1o b\u1ea3o h\u1ed9 v\u00e0 s\u1eed d\u1ee5ng kem ch\u1ed1ng n\u1eafng c\u00f3 ch\u1ec9 s\u1ed1 SPF cao trong su\u1ed1t th\u1eddi gian \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>N\u1ebfu xu\u1ea5t hi\u1ec7n ph\u00e1t ban ho\u1eb7c t\u1ed5n th\u01b0\u01a1ng da ti\u1ebfn tri\u1ec3n, ng\u1eebng thu\u1ed1c v\u00e0 th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129.<\/p>\n<p>Khi \u0111i\u1ec1u tr\u1ecb k\u00e9o d\u00e0i tr\u00ean 180 ng\u00e0y, c\u1ea7n \u0111\u00e1nh gi\u00e1 \u0111\u1ecbnh k\u1ef3 gi\u1eefa l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 tr\u01b0\u1edbc khi ti\u1ebfp t\u1ee5c s\u1eed d\u1ee5ng.<\/p>\n<p>Theo d\u00f5i da \u0111\u1ecbnh k\u1ef3 n\u1ebfu ph\u1ea3i \u0111i\u1ec1u tr\u1ecb k\u00e9o d\u00e0i ho\u1eb7c c\u00f3 bi\u1ec3u hi\u1ec7n t\u1ed5n th\u01b0\u01a1ng da do \u00e1nh s\u00e1ng; ng\u1eebng thu\u1ed1c khi ph\u00e1t hi\u1ec7n t\u1ed5n th\u01b0\u01a1ng ti\u1ec1n ung th\u01b0 ho\u1eb7c ung th\u01b0 da.<\/p>\n<p>N\u1ebfu xu\u1ea5t hi\u1ec7n \u0111au x\u01b0\u01a1ng k\u00e9o d\u00e0i ho\u1eb7c nghi ng\u1edd vi\u00eam m\u00e0ng x\u01b0\u01a1ng, c\u1ea7n \u0111\u00e1nh gi\u00e1 l\u1ea1i v\u00e0 c\u00e2n nh\u1eafc ng\u1eebng thu\u1ed1c.<\/p>\n<p>Theo d\u00f5i c\u00e1c tri\u1ec7u ch\u1ee9ng b\u1ea5t th\u01b0\u1eddng v\u1ec1 th\u1ecb gi\u00e1c; ng\u1eebng thu\u1ed1c v\u00e0 kh\u00e1m chuy\u00ean khoa n\u1ebfu r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c k\u00e9o d\u00e0i.<\/p>\n<p>Theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn, bao g\u1ed3m creatinin huy\u1ebft thanh, trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Theo d\u00f5i amylase ho\u1eb7c lipase \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 vi\u00eam t\u1ee5y, \u0111\u1eb7c bi\u1ec7t l\u00e0 tr\u1ebb em sau h\u00f3a tr\u1ecb ho\u1eb7c gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c.<\/p>\n<p>\u1ede tr\u1ebb em, c\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng gan v\u00e0 b\u1ea3o v\u1ec7 da kh\u1ecfi \u00e1nh n\u1eafng nghi\u00eam ng\u1eb7t; \u01b0u ti\u00ean d\u1ea1ng ti\u00eam n\u1ebfu tr\u1ebb t\u1eeb 2 \u0111\u1ebfn d\u01b0\u1edbi 12 tu\u1ed5i b\u1ecb k\u00e9m h\u1ea5p thu ho\u1eb7c c\u00f3 c\u00e2n n\u1eb7ng r\u1ea5t th\u1ea5p.<\/p>\n<p>C\u1ea7n l\u01b0u \u00fd th\u00e0nh ph\u1ea7n lactose monohydrat trong thu\u1ed1c. Nh\u1eefng ng\u01b0\u1eddi m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n di truy\u1ec1n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn chuy\u1ec3n h\u00f3a galactose ho\u1eb7c h\u1ea5p thu glucose &#8211; galactose n\u00ean tr\u00e1nh s\u1eed d\u1ee5ng.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>R\u1ea5t th\u01b0\u1eddng g\u1eb7p (\u2265 1\/10): S\u1ed1t r\u00e9t, ph\u00f9 ngo\u1ea1i bi\u00ean, \u0111au \u0111\u1ea7u, suy gi\u1ea3m th\u1ecb l\u1ef1c, suy h\u00f4 h\u1ea5p, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, b\u1ea5t th\u01b0\u1eddng ch\u1ee9c n\u0103ng gan, ph\u00e1t ban\u2026.<\/p>\n<p>Th\u01b0\u1eddng g\u1eb7p (1\/100 \u2264 ADR &lt; 1\/10) Vi\u00eam xoang, thi\u1ebfu m\u00e1u, gi\u1ea3m b\u1ea1ch c\u1ea7u\/ti\u1ec3u c\u1ea7u, h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, tr\u1ea7m c\u1ea3m, lo \u00e2u, m\u1ea5t ng\u1ee7, \u1ea3o gi\u00e1c, co gi\u1eadt, run, ch\u00f3ng m\u1eb7t, nh\u1ecbp tim nhanh\/ch\u1eadm, h\u1ea1 huy\u1ebft \u00e1p, vi\u00eam gan, v\u00e0ng da, ng\u1ee9a, r\u1ee5ng t\u00f3c, suy th\u1eadn c\u1ea5p, \u0111au ng\u1ef1c&#8230;<\/p>\n<p>\u00cdt g\u1eb7p (1\/1000 \u2264 ADR &lt; 1\/100) : Vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn, suy t\u1ee7y x\u01b0\u01a1ng, suy gi\u00e1p, ph\u00f9 n\u00e3o, gi\u1ea3m th\u00ednh l\u1ef1c, \u00f9 tai, nh\u00ecn \u0111\u00f4i, rung th\u1ea5t, nh\u1ecbp nhanh th\u1ea5t, kho\u1ea3ng QT k\u00e9o d\u00e0i, vi\u00eam t\u1ee5y, suy gan, gan to, h\u1ed9i ch\u1ee9ng Stevens-Johnson, \u0111\u1ed9c t\u00ednh quang h\u1ecdc, vi\u00eam th\u1eadn&#8230;<\/p>\n<p>Hi\u1ebfm g\u1eb7p (1\/10000 \u2264 ADR &lt; 1\/1000) \u0110\u00f4ng m\u00e1u n\u1ed9i m\u1ea1ch r\u1ea3i r\u00e1c, ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, b\u1ec7nh n\u00e3o gan, h\u1ed9i ch\u1ee9ng Guillain-Barre, xo\u1eafn \u0111\u1ec9nh, block nh\u0129 th\u1ea5t ho\u00e0n to\u00e0n, ho\u1ea1i t\u1eed th\u01b0\u1ee3ng b\u00ec nhi\u1ec5m \u0111\u1ed9c, ph\u00f9 m\u1ea1ch, h\u1ed9i ch\u1ee9ng DRESS&#8230;<\/p>\n<p>T\u1ea7n su\u1ea5t kh\u00f4ng x\u00e1c \u0111\u1ecbnh: Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o v\u1ea3y, lupus ban \u0111\u1ecf, t\u00e0n nhang, \u0111\u1ed3i m\u1ed3i, vi\u00eam m\u00e0ng x\u01b0\u01a1ng.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng \u0111\u1ed3ng th\u1eddi: Astemizole, cisapride, pimozide, quinidine, terfenadine, carbamazepine, phenobarbital, mephobarbital, rifampicin, ritonavir (li\u1ec1u cao \u2265 400mg x 2 l\u1ea7n\/ng\u00e0y), ergotamine, dihydroergotamine, sirolimus, c\u1ecf Th\u00e1nh John (St. John&#8217;s Wort), efavirenz (li\u1ec1u \u2265 400mg x 1 l\u1ea7n\/ng\u00e0y).<\/p>\n<p>Tr\u00e1nh s\u1eed d\u1ee5ng (tr\u1eeb khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i ho\u1eb7c c\u1ea7n ch\u1ec9nh li\u1ec1u): Rifabutin, phenytoin, ritonavir (li\u1ec1u th\u1ea5p 100mg x 2 l\u1ea7n\/ng\u00e0y), everolimus.<\/p>\n<p>C\u1ea7n theo d\u00f5i s\u00e1t, th\u1eadn tr\u1ecdng ho\u1eb7c hi\u1ec7u ch\u1ec9nh li\u1ec1u: Efavirenz (li\u1ec1u th\u1ea5p), fluconazole, thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1eddng u\u1ed1ng, midazolam, triazolam, alprazolam, tacrolimus, ciclosporin, oxycodone, hydrocodone, alfentanil, fentanyl, sufentanil, methadone, c\u00e1c thu\u1ed1c NSAID, thu\u1ed1 tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng, c\u00e1c thu\u1ed1c nh\u00f3m statin, sulfonylurea, vincristine, vinblastine, saquinav amprenavir, nelfinavir, delavirdine, nevirapine v\u00e0 c\u00e1c thu\u1ed1c g\u00e2y k\u00e9o d\u00e0i kho\u1ea3ng QT.<\/p>\n<p>Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u khi ph\u1ed1i h\u1ee3p: Cimetidine, digoxin, indinavir, kh\u00e1ng sinh nh\u00f3m macrolide, mycophenolic acid, prednisolone, ranitidine.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef \u0111ang mang thai: D\u1eef li\u1ec7u l\u00e2m s\u00e0ng v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng Voriconazole cho thai ph\u1ee5 v\u1eabn ch\u01b0a \u0111\u1ea7y \u0111\u1ee7. Tuy nhi\u00ean, c\u00e1c nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt th\u1ef1c nghi\u1ec7m \u0111\u00e3 ghi nh\u1eadn \u0111\u1ed9c t\u00ednh c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u1ed1i v\u1edbi qu\u00e1 tr\u00ecnh sinh s\u1ea3n. M\u1eb7c d\u00f9 nguy c\u01a1 tr\u1ef1c ti\u1ebfp tr\u00ean c\u01a1 th\u1ec3 ng\u01b0\u1eddi ch\u01b0a \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp c\u1ee5 th\u1ec3, nh\u01b0ng tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng d\u00f9ng thu\u1ed1c cho \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y, tr\u1eeb khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh b\u1eaft bu\u1ed9c t\u1eeb b\u00e1c s\u0129<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 kh\u1ea3 n\u0103ng th\u1ee5 thai: B\u1eaft bu\u1ed9c ph\u1ea3i \u00e1p d\u1ee5ng li\u00ean t\u1ee5c c\u00e1c bi\u1ec7n ph\u00e1p tr\u00e1nh thai mang trong su\u1ed1t th\u1eddi gian \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Voriconazole.<\/p>\n<p>Kh\u1ea3 n\u0103ng sinh s\u1ea3n: Th\u1eed nghi\u1ec7m tr\u00ean \u0111\u1ed9ng v\u1eadt (chu\u1ed9t \u0111\u1ef1c v\u00e0 chu\u1ed9t c\u00e1i) cho th\u1ea5y thu\u1ed1c kh\u00f4ng g\u00e2y suy gi\u1ea3m kh\u1ea3 n\u0103ng sinh s\u1ea3n.<\/p>\n<p>Ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa: Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u x\u00e1c \u0111\u1ecbnh li\u1ec7u ho\u1ea1t ch\u1ea5t c\u1ee7a Galfend c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng. V\u00ec v\u1eady, ng\u01b0\u1eddi m\u1eb9 ph\u1ea3i ng\u1eebng cho con b\u00fa ngay khi b\u1eaft \u0111\u1ea7u b\u01b0\u1edbc v\u00e0o li\u1ec7u tr\u00ecnh \u0111i\u1ec1u tr\u1ecb v\u1edbi Voriconazole.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 m\u1ee9c \u0111\u1ed9 \u1ea3nh h\u01b0\u1edfng trung b\u00ecnh \u0111\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi c\u1ea7n v\u1eadn h\u00e0nh m\u00e1y m\u00f3c hay \u0111i\u1ec1u khi\u1ec3n ph\u01b0\u01a1ng ti\u1ec7n giao th\u00f4ng. Ho\u1ea1t ch\u1ea5t n\u00e0y c\u00f3 th\u1ec3 g\u00e2y ra nh\u1eefng r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c mang t\u00ednh ch\u1ea5t t\u1ea1m th\u1eddi v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng t\u1ef1 ph\u1ee5c h\u1ed3i (nh\u01b0 nh\u00ecn m\u1edd, ch\u1ee9ng s\u1ee3 \u00e1nh s\u00e1ng, ho\u1eb7c l\u00e0m t\u0103ng\/gi\u1ea3m th\u1ecb l\u1ef1c). Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n \u0111\u1eb7c bi\u1ec7t l\u01b0u \u00fd kh\u00f4ng th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c c\u00f3 \u0111\u1ed9 nguy hi\u1ec3m cao nh\u01b0 l\u00e1i xe hay \u0111i\u1ec1u khi\u1ec3n m\u00e1y m\u00f3c khi c\u01a1 th\u1ec3 \u0111ang xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng v\u1ec1 th\u1ecb gi\u00e1c k\u1ec3 tr\u00ean.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u: Ghi nh\u1eadn th\u1ef1c t\u1ebf l\u00e2m s\u00e0ng c\u00f3 3 tr\u01b0\u1eddng h\u1ee3p d\u00f9ng qu\u00e1 li\u1ec1u do v\u00f4 \u00fd, t\u1ea5t c\u1ea3 \u0111\u1ec1u x\u1ea3y ra \u1edf \u0111\u1ed1i t\u01b0\u1ee3ng tr\u1ebb em v\u1edbi li\u1ec1u d\u00f9ng g\u1ea5p 5 l\u1ea7n m\u1ee9c khuy\u1ebfn c\u00e1o c\u1ee7a d\u1ea1ng truy\u1ec1n t\u0129nh m\u1ea1ch. Bi\u1ec3u hi\u1ec7n ghi nh\u1eadn \u0111\u01b0\u1ee3c l\u00e0 ch\u1ee9ng s\u1ee3 \u00e1nh s\u00e1ng k\u00e9o d\u00e0i trong kho\u1ea3ng th\u1eddi gian 10 ph\u00fat.<\/p>\n<p>X\u1eed tr\u00ed: Hi\u1ec7n t\u1ea1i, ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho Voriconazole. Trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p x\u1ea3y ra qu\u00e1 li\u1ec1u, ph\u01b0\u01a1ng ph\u00e1p th\u1ea9m t\u00e1ch m\u00e1u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng \u0111\u1ec3 h\u1ed7 tr\u1ee3 \u0111\u00e0o th\u1ea3i ho\u1ea1t ch\u1ea5t n\u00e0y ra kh\u1ecfi c\u01a1 th\u1ec3 v\u1edbi ch\u1ec9 s\u1ed1 \u0111\u1ed9 thanh l\u1ecdc \u0111\u1ea1t m\u1ee9c 121 ml\/ph\u00fat.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Galfend 200mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Galfend 200mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Galfend 200mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>Thu\u1ed1c Galfend 200mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Galfend 200mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Galfend 200mg c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Galfend 200mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Galfend 200mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/voriole-200mg\/\">Voriole 200mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Voriconazole 200mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi MSN Laborratories Private Limited, \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m Aspergillus spp. v\u00e0 Candida spp,&#8230;<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/myvorcon-200mg\/\">MyVorcon 200mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Voriconazole 200mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Mylan Laboratories Limited, \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m n\u1ea5m Aspergillus spp. v\u00e0 Candida spp,&#8230;<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Galfend 200mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2026\/06\/to-huong-dan-su-dung-Galfend-200mg-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 19 th\u00e1ng 6 n\u0103m 2026<\/li>\n<li>Greer ND (2003). Voriconazole: the newest triazole antifungal agent. Proc (Bayl Univ Med Cent). Truy c\u1eadp ng\u00e0y 19 th\u00e1ng 6 n\u0103m 2026 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1201014\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1201014\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Galfend 200mg ch\u1ee9a ho\u1ea1t ch\u1ea5t Voriconazole, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m n\u1ea5m x\u00e2m l\u1ea5n nghi\u00eam tr\u1ecdng v\u00e0 d\u1ef1 ph\u00f2ng nhi\u1ec5m n\u1ea5m \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao<\/p>\n","protected":false},"author":1,"featured_media":158933,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-158931","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/158931","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=158931"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/158933"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=158931"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=158931"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=158931"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}