{"id":15549,"date":"2019-07-19T16:15:53","date_gmt":"2019-07-19T09:15:53","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?post_type=product&#038;p=15549"},"modified":"2025-07-24T14:37:02","modified_gmt":"2025-07-24T07:37:02","slug":"plendil-plus","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/plendil-plus\/","title":{"rendered":"Plendil Plus"},"content":{"rendered":"<p>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"http:\/\/vnras.com\/drug\/\">nh\u00e0 thu\u1ed1c L\u01b0u V\u0103n Ho\u00e0ng<\/a> xin gi\u1edbi thi\u1ec7u t\u1edbi b\u1ea1n \u0111\u1ecdc <a href=\"https:\/\/www.vnras.com\/drug\/plendil-plus\"><strong>thu\u1ed1c Plendil Plus<\/strong><\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00f4ng ty AstraZeneca A.B &#8211; TH\u1ee4Y \u0110I\u1ec2N, \u0111\u01b0\u1ee3c \u0111\u0103ng k\u00fd b\u1edfi c\u00f4ng ty AstraZeneca Singapore Pte., Ltd v\u1edbi s\u1ed1 \u0111\u0103ng k\u00ed VN-9414-05.<\/p>\n<h2>Thu\u1ed1c Plendil Plus l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<p><strong>Thu\u1ed1c Plendil Plus<\/strong> l\u00e0 thu\u1ed1c d\u00f9ng \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p d\u1ef1a v\u00e0o vi\u1ec7c \u1ee9c ch\u1ebf k\u00eanh Calci\u00a0 tr\u00ean th\u00e0nh m\u1ea1ch m\u00e1u. Thu\u1ed1c c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng \u0111\u01a1n \u0111\u1ed9c ho\u1eb7c k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p kh\u00e1c.<\/p>\n<p>Th\u00e0nh ph\u1ea7n: th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ee7a thu\u1ed1c l\u00e0 Felodipine k\u1ebft h\u1ee3p Metoprolol v\u1edbi h\u00e0m l\u01b0\u1ee3ng 5mg v\u00e0 t\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean ph\u00f3ng th\u00edch ch\u1eadm.<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: m\u1ed9t h\u1ed9p 1 l\u1ecd 30 vi\u00ean.<\/p>\n<p>C\u00e1ch b\u1ea3o qu\u1ea3n: b\u1ea3o qu\u1ea3n n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t. Kh\u00f4ng \u0111\u1ec3 thu\u1ed1c trong t\u1ea7m v\u1edbi c\u1ee7a tr\u1ebb.<\/p>\n<p>Ng\u00e0y s\u1ea3n xu\u1ea5t v\u00e0 h\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng k\u1ec3 t\u1eeb ng\u00e0y s\u1ea3n xu\u1ea5t.<\/p>\n<h2>Thu\u1ed1c Plendil Plus b\u00e1n \u1edf \u0111\u00e2u? Gi\u00e1 bao nhi\u00eau?<\/h2>\n<p><strong>Thu\u1ed1c Plendil Plus<\/strong> hi\u1ec7n \u0111\u01b0\u1ee3c b\u00e1n tr\u00ean th\u1ecb tr\u01b0\u1eddng v\u1edbi gi\u00e1 430.000 \u0111\u1ed3ng m\u1ed9t h\u1ed9p. Nh\u00e0 thu\u1ed1c L\u01b0u V\u0103n Ho\u00e0ng ch\u00fang t\u00f4i hi\u1ec7n c\u00f3 b\u00e1n s\u1ea3n ph\u1ea9m n\u00e0y. Vui l\u00f2ng li\u00ean h\u1ec7 v\u1edbi ch\u00fang t\u00f4i \u0111\u1ec3 \u0111\u1eb7t mua s\u1ea3n ph\u1ea9m v\u00e0 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n mi\u1ec5n ph\u00ed.<\/p>\n<p>M\u1eddi b\u1ea1n \u0111\u1ecdc tham kh\u1ea3o m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i:<\/p>\n<ul>\n<li>Thu\u1ed1c\u00a0<a href=\"https:\/\/www.vnras.com\/drug\/mezathion\">Mezathion<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c Ph\u1ea9m H\u00e0 T\u00e2y \u2013 Vi\u1ec7t Nam.<\/li>\n<li>Thu\u1ed1c\u00a0<a href=\"https:\/\/www.vnras.com\/drug\/apitim-5mg\">Apitim 5mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1ea1i\u00a0C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c H\u1eadu Giang \u2013 VI\u1ec6T NAM.<\/li>\n<li><a href=\"https:\/\/www.vnras.com\/drug\/cordaflex\">Thu\u1ed1c\u00a0Cordaflex<\/a>\u00a0\u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Egis Pharma Public, Ltd., Co \u2013 Hungary.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Plendil Plus c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n<p><strong>Thu\u1ed1c Plendil Plus<\/strong> l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p d\u1ef1a v\u00e0o s\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a hai ho\u1ea1t ch\u1ea5t th\u00e0nh ph\u1ea7n. Trong \u0111\u00f3, Felodipin l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc k\u00eanh Calci, g\u00e2y gi\u00e3n m\u1ea1ch, gi\u1ea3m s\u1ee9c c\u1ea3n ngo\u1ea1i vi, h\u1ea1 huy\u1ebft \u00e1p. Metroprolon l\u00e0 ch\u1ea5t \u1ee9c ch\u00ea ch\u1ecdn l\u1ecdc th\u1ee5 th\u1ec3 Beta-1, n\u1eb1m ch\u1ee7 y\u1ebfu \u1edf c\u01a1 tim. Thu\u1ed1c l\u00e0m gi\u1ea3m t\u00e1c \u0111\u1ed9ng c\u01b0\u1eddng giao c\u1ea3m tr\u00ean tim do c\u00e1c catecholamine g\u00e2y ra. V\u00ec v\u1eady, thu\u1ed1c l\u00e0m ch\u1eadm nh\u1ecbp tim, h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng thu\u1ed1c<\/h2>\n<p>V\u1ec1 c\u00e1ch d\u00f9ng: thu\u1ed1c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng. Thu\u1ed1c l\u00e0 vi\u00ean gi\u1ea3i ph\u00f3ng ch\u1eadm n\u00ean kh\u00f4ng \u0111\u01b0\u1ee3c b\u1ebb thu\u1ed1c khi u\u1ed1ng. Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c u\u1ed1ng khi \u0111\u00f3i hay khi \u0103n nh\u1eb9.<\/p>\n<p>V\u1ec1 li\u1ec1u d\u00f9ng: \u0111\u00e2y l\u00e0 thu\u1ed1c k\u00ea \u0111\u01a1n n\u00ean kh\u00f4ng \u0111\u01b0\u1ee3c ph\u00e9p t\u1ef1 \u00fd s\u1eed d\u1ee5ng thu\u1ed1c.<\/p>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u01b0\u1eddng d\u1ef1a v\u00e0o li\u1ec1u c\u1ee7a c\u00e1c thu\u1ed1c ch\u1eb9n k\u00eanh Calci v\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf Beta adrenergic tr\u01b0\u1edbc \u0111\u00e2y. Li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c nh\u00e0 s\u1ea3n xu\u1ea5t khuy\u1ebfn c\u00e1o l\u00e0 1 vi\u00ean\/ ng\u00e0y, u\u1ed1ng v\u00e0o bu\u1ed5i s\u00e1ng. N\u00ean u\u1ed1ng c\u00f9ng th\u1eddi \u0111i\u1ec3m \u0111\u1ec3 tr\u00e1nh qu\u00ean thu\u1ed1c.<\/p>\n<p>Trong m\u1ed9t v\u00e0i tr\u01b0\u1eddng h\u1ee3p, c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u l\u00ean 2 vi\u00ean\/ ng\u00e0y.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Plendil Plus khi n\u00e0o?<\/h2>\n<ul>\n<li>Kh\u00f4ng d\u00f9ng cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi b\u1ea5t k\u00ec th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai.<\/li>\n<li>Kh\u00f4ng d\u00f9ng cho ng\u01b0\u1eddi m\u1eafc m\u1ed9t s\u1ed1 b\u1ec7nh tim m\u1ea1ch nh\u01b0: c\u01a1n \u0111au thatw ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh, suy tim m\u1ea5t b\u00f9 kh\u00f4ng \u1ed5n \u0111\u1ecbnh, ng\u01b0\u1eddi \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c ch\u1ee7 v\u1eadn Beta.<\/li>\n<li>Kh\u00f4ng d\u00f9ng cho ng\u01b0\u1eddi ch\u1eadm nh\u1ecbp tim c\u00f3 nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p, suy n\u00fat xoang.<\/li>\n<li>Kh\u00f4ng d\u00f9ng cho ng\u01b0\u1eddi nghi ng\u1edd nh\u1ed3i m\u00e1u c\u01a1 tim.<\/li>\n<\/ul>\n<h2>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng thu\u1ed1c Plendil Plus<\/h2>\n<p>Th\u00e2n tr\u1ecdng khi s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi digitalis do c\u00f3 th\u1ec3 g\u00e2y suy th\u1eadn, l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam c\u00e1c tri\u1ec7u ch\u1ee9ng ngo\u1ea1i bi\u00ean, nh\u1ed3i m\u00e1u c\u01a1 tim, h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<p>Vi\u1ec7c d\u00f9ng thu\u1ed1c \u1ea3nh h\u01b0\u1edfng t\u1edbi qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a carbohydrat c\u1ee7a c\u01a1 th\u1ec3, che l\u1ea5p c\u00e1c bi\u1ec3u hi\u1ec7n h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft \u1edf ng\u01b0\u1eddi d\u00f9ng. V\u00ec v\u1eady, c\u1ea7n th\u1eadn trong khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi m\u1eafc c\u00e1c b\u1ec7nh \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p nh\u01b0 hen ph\u1ebf qu\u1ea3n, b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh do thu\u1ed1c \u1ee9c ch\u1ebf c\u1ea3 th\u1ee5 th\u00ea beta2- adrenergic. N\u00ean s\u1eed d\u1ee5ng th\u00eam c\u00e1c thu\u1ed1c gi\u00e3n ph\u1ebf qu\u1ea3n \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y.<\/p>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y \u1ea3nh h\u01b0\u1edfng trong \u0111i\u1ec1u tr\u1ecb c\u00e1c ph\u1ea3n \u1ee9ng s\u1ed1c ph\u1ea3n v\u1ec7 c\u1ee7a c\u01a1 th\u1ec3 khi s\u1eed d\u1ee5ng adrenalin.<\/p>\n<p>Kh\u00f4ng ng\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t m\u00e0 c\u1ea7n gi\u1ea3m li\u1ec1u t\u1eeb t\u1eeb \u0111\u1ec3 tr\u00e1nh tr\u01b0\u1eddng h\u1ee3p ph\u1ea3n \u1ee9ng b\u1eadt l\u1ea1i, t\u0103ng nguy c\u01a1 x\u1ea3y ra nh\u1ed3i m\u00e1u c\u01a1 tim.<\/p>\n<h2>T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a Plendil Plus<\/h2>\n<p>Khi s\u1eed d\u1ee5ng thu\u1ed1c, c\u00e1c ph\u1ea3n \u1ee9ng ch\u1ee7 y\u1ebfu g\u1eb7p ph\u1ea3i l\u00e0 t\u00ecnh tr\u1ea1ng nh\u1ee9c \u0111\u1ea7u, \u0111\u1ecf m\u1eb7t v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00f9 m\u1eaft c\u00e1 ch\u00e2n. \u0110\u00e2y l\u00e0 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a Felodipin do t\u00e1c d\u1ee5ng gi\u00e3n m\u1ea1ch ngo\u1ea1i vi. C\u00e1c tri\u1ec7u ch\u1ee9ng ng\u00e0y th\u01b0\u1eddng xu\u1ea5t hi\u1ec7n khi b\u1eaft \u0111\u1ea7u s\u1eed d\u1ee5ng thu\u1ed1c ho\u1eb7c khi t\u0103ng li\u1ec1u.<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng thu\u1ed1c Plendil Plus \u0111\u01b0\u1ee3c kh\u00f4ng?<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai: ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: n\u00ean th\u1eadn tr\u1ecdng khi d\u00f9ng, ch\u1ec9 d\u00f9ng thu\u1ed1c khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129.<\/p>\n<h2>Ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c c\u00f3 s\u1eed d\u1ee5ng thu\u1ed1c Plendil Plus \u0111\u01b0\u1ee3c kh\u00f4ng?<\/h2>\n<p>C\u00f3 th\u1ec3 s\u1eed d\u1ee5ng thu\u1ed1c cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h2>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h2>\n<p>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng c\u00f9ng c\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng ho\u1eb7c \u1ee9c ch\u1ebf enzyme chuy\u1ec3n h\u00f3a CYP3A4 c\u1ee7a gan do \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 Plendil Plus trong c\u01a1 th\u1ec3.<\/p>\n<p>M\u1ed9t s\u1ed1 thu\u1ed1c c\u1ea3m \u1ee9ng enzyme nh\u01b0: carbamazepine, phenytoin, rifampicin. C\u00e1c thu\u1ed1c n\u00e0y l\u00e0m t\u0103ng chuy\u1ec3n h\u00f3a thu\u1ed1c, t\u0103ng \u0111\u00e0o th\u1ea3i Plendil Plus ra kh\u1ecfi c\u01a1 th\u1ec3, gi\u1ea3m n\u1ed3ng \u0111\u1ed9 c\u00f3 th\u1ec3 d\u1eabn t\u1edbi m\u1ea5t t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c.<\/p>\n<p>M\u1ed9t s\u1ed1 thu\u1ed1c \u1ee9c ch\u1ebf enzyme nh\u01b0: thu\u1ed1c kh\u00e1ng n\u1ea5m c\u00f3 c\u1ea5u tr\u00fac azol, kh\u00e1ng sinh macrolid,\u2026 Qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a thu\u1ed1c.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng c\u00f9ng m\u1ed9t s\u1ed1 thu\u1ed1c nh\u01b0: cietidin, SSRI, acid barbituric.<\/p>\n<p>Ch\u00fa \u00fd ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, kh\u00f4ng n\u00ean u\u1ed1ng n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi c\u00f9ng v\u1edbi thu\u1ed1c do l\u00e0m t\u0103ng h\u1ea5p thu thu\u1ed1c.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Trong b\u00e0i vi\u1ebft n\u00e0y, nh\u00e0 thu\u1ed1c L\u01b0u V\u0103n Ho\u00e0ng xin gi\u1edbi thi\u1ec7u t\u1edbi b\u1ea1n \u0111\u1ecdc thu\u1ed1c Plendil Plus \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00f4ng ty AstraZeneca A.B &#8211; TH\u1ee4Y \u0110I\u1ec2N, \u0111\u01b0\u1ee3c \u0111\u0103ng k\u00fd b\u1edfi c\u00f4ng ty AstraZeneca Singapore Pte., Ltd v\u1edbi s\u1ed1 \u0111\u0103ng k\u00ed VN-9414-05. Thu\u1ed1c Plendil Plus l\u00e0 thu\u1ed1c g\u00ec? Thu\u1ed1c Plendil Plus l\u00e0 thu\u1ed1c [&#8230;]\n","protected":false},"author":1,"featured_media":89326,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-15549","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/15549","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=15549"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/89326"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=15549"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=15549"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=15549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}