{"id":149177,"date":"2025-11-25T13:35:25","date_gmt":"2025-11-25T06:35:25","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=149177"},"modified":"2025-11-25T13:36:47","modified_gmt":"2025-11-25T06:36:47","slug":"amlessa-4mg-5mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/amlessa-4mg-5mg\/","title":{"rendered":"Amlessa 4mg\/5mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Amlessa 4mg\/5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi KRKA, d. d., Novo mesto, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 383110520324.<\/strong><\/p>\n<h2>Amlessa 4mg\/5mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Amlessa 4mg\/5mg<\/strong> l\u00e0 thu\u1ed1c tim m\u1ea1ch c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<p>Perindopril tert-butylamine: 4mg (T\u01b0\u01a1ng \u0111\u01b0\u01a1ng 3,34mg Perindopril).<\/p>\n<p><strong>Amlodipin<\/strong>: 5mg (D\u01b0\u1edbi d\u1ea1ng Amlodipine besilate).<\/p>\n<p>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 383110520324<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Slovenia<\/p>\n<figure id=\"attachment_149181\" aria-describedby=\"caption-attachment-149181\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-149181\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Amlessa-4mg5mg.jpg\" alt=\"Amlessa 4mg\/5mg \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Amlessa-4mg5mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Amlessa-4mg5mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Amlessa-4mg5mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Amlessa-4mg5mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Amlessa-4mg5mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-149181\" class=\"wp-caption-text\">Amlessa 4mg\/5mg \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Amlessa 4mg\/5mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Perindopril (Nh\u00f3m ACEI): Ho\u1ea1t ch\u1ea5t n\u00e0y ng\u0103n ch\u1eb7n qu\u00e1 tr\u00ecnh chuy\u1ec3n \u0111\u1ed5i Angiotensin I th\u00e0nh Angiotensin II (m\u1ed9t ch\u1ea5t g\u00e2y co m\u1ea1ch m\u1ea1nh). Nh\u1edd \u0111\u00f3, m\u1ea1ch m\u00e1u \u0111\u01b0\u1ee3c gi\u00e3n ra, s\u1ee9c c\u1ea3n ngo\u1ea1i vi gi\u1ea3m xu\u1ed1ng, gi\u00fap tim b\u01a1m m\u00e1u nh\u1eb9 nh\u00e0ng h\u01a1n.<\/p>\n<p>Amlodipin (Nh\u00f3m CCB): T\u00e1c \u0111\u1ed9ng tr\u1ef1c ti\u1ebfp b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf d\u00f2ng ion calci \u0111i v\u00e0o t\u1ebf b\u00e0o c\u01a1 tr\u01a1n m\u1ea1ch m\u00e1u v\u00e0 c\u01a1 tim, g\u00e2y gi\u00e3n c\u00e1c ti\u1ec3u \u0111\u1ed9ng m\u1ea1ch ngo\u1ea1i bi\u00ean, t\u1eeb \u0111\u00f3 h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<p>S\u1ef1 k\u1ebft h\u1ee3p gi\u1eefa Perindopril v\u00e0 Amlodipin mang l\u1ea1i hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p m\u1ea1nh m\u1ebd h\u01a1n so v\u1edbi d\u00f9ng \u0111\u01a1n l\u1ebb.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Perindopril h\u1ea5p thu nhanh nh\u01b0ng c\u1ea7n l\u01b0u \u00fd l\u00e0 th\u1ee9c \u0103n l\u00e0m gi\u1ea3m s\u1ef1 chuy\u1ec3n h\u00f3a th\u00e0nh ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh (Perindoprilat). Trong khi \u0111\u00f3, Amlodipin h\u1ea5p thu ch\u1eadm h\u01a1n v\u00e0 kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n.<\/p>\n<p>Chuy\u1ec3n h\u00f3a &amp; Th\u1ea3i tr\u1eeb: C\u1ea3 hai \u0111\u1ec1u chuy\u1ec3n h\u00f3a qua gan v\u00e0 th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u. Th\u1eddi gian b\u00e1n th\u1ea3i d\u00e0i cho ph\u00e9p b\u1ec7nh nh\u00e2n ch\u1ec9 c\u1ea7n d\u00f9ng thu\u1ed1c 1 l\u1ea7n duy nh\u1ea5t trong ng\u00e0y.<\/p>\n<h2>Thu\u1ed1c Amlessa 4mg\/5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c Amlessa 4mg\/5mg kh\u00f4ng ph\u1ea3i l\u00e0 thu\u1ed1c d\u00f9ng \u0111\u1ec3 kh\u1edfi \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb (d\u00f2 li\u1ec1u). Thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p thay th\u1ebf trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p:<\/p>\n<p>T\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n.<\/p>\n<p>B\u1ec7nh m\u1ea1ch v\u00e0nh \u1ed5n \u0111\u1ecbnh.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c<\/h2>\n<h3>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c<\/h3>\n<p>Li\u1ec1u th\u00f4ng th\u01b0\u1eddng l\u00e0 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y.<\/p>\n<h3>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c<\/h3>\n<p>U\u1ed1ng nguy\u00ean vi\u00ean thu\u1ed1c v\u1edbi m\u1ed9t c\u1ed1c n\u01b0\u1edbc l\u1ecdc. Tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng nhai ho\u1eb7c b\u1ebb vi\u00ean thu\u1ed1c tr\u1eeb khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh \u0111\u1eb7c bi\u1ec7t.<\/p>\n<p>Th\u1eddi \u0111i\u1ec3m v\u00e0ng: N\u00ean u\u1ed1ng v\u00e0o bu\u1ed5i s\u00e1ng, tr\u01b0\u1edbc b\u1eefa \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Amlessa 4mg\/5mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng ho\u1eb7c qu\u00e1 m\u1eabn v\u1edbi Perindopril (ho\u1eb7c c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n kh\u00e1c), Amlodipin (ho\u1eb7c c\u00e1c thu\u1ed1c nh\u00f3m dihydropyridin).<\/p>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed ph\u00f9 m\u1ea1ch (ph\u00f9 Quincke) do di truy\u1ec1n, t\u1ef1 ph\u00e1t ho\u1eb7c do d\u00f9ng thu\u1ed1c ACEI tr\u01b0\u1edbc \u0111\u00e2y.<\/p>\n<p>Ph\u1ee5 n\u1eef mang thai (\u0110\u1eb7c bi\u1ec7t l\u00e0 qu\u00fd 2 v\u00e0 qu\u00fd 3 thai k\u1ef3).<\/p>\n<p>Ng\u01b0\u1eddi b\u1ecb suy tim sung huy\u1ebft kh\u00f4ng \u1ed5n \u0111\u1ecbnh sau nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p.<\/p>\n<p>B\u1ec7nh nh\u00e2n b\u1ecb h\u1eb9p \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 n\u1eb7ng, s\u1ed1c tim ho\u1eb7c h\u1ea1 huy\u1ebft \u00e1p qu\u00e1 m\u1ee9c.<\/p>\n<p>H\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn hai b\u00ean ho\u1eb7c h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn \u1edf ng\u01b0\u1eddi ch\u1ec9 c\u00f2n m\u1ed9t qu\u1ea3 th\u1eadn.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p: C\u00f3 th\u1ec3 x\u1ea3y ra \u1edf li\u1ec1u \u0111\u1ea7u ti\u00ean, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi \u0103n nh\u1ea1t, \u0111ang d\u00f9ng thu\u1ed1c l\u1ee3i ti\u1ec3u ho\u1eb7c ng\u01b0\u1eddi gi\u00e0. N\u00ean n\u1eb1m ngh\u1ec9 n\u1ebfu th\u1ea5y ch\u00f3ng m\u1eb7t.<\/p>\n<p>Ch\u1ee9c n\u0103ng gan\/th\u1eadn: C\u1ea7n theo d\u00f5i \u0111\u1ecbnh k\u1ef3 creatinin v\u00e0 kali m\u00e1u, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn ho\u1eb7c ng\u01b0\u1eddi cao tu\u1ed5i. V\u1edbi b\u1ec7nh nh\u00e2n suy gan, th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a Amlodipin k\u00e9o d\u00e0i n\u00ean c\u1ea7n th\u1eadn tr\u1ecdng.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Ho khan: \u0110\u00e2y l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 \u0111i\u1ec3n h\u00ecnh c\u1ee7a nh\u00f3m \u1ee9c ch\u1ebf men chuy\u1ec3n (do Perindopril). Ho th\u01b0\u1eddng dai d\u1eb3ng v\u00e0 ch\u1ec9 h\u1ebft khi ng\u01b0ng thu\u1ed1c.<\/p>\n<p>Ph\u00f9 ch\u00e2n: M\u1eb7c d\u00f9 Perindopril gi\u00fap gi\u1ea3m nguy c\u01a1 n\u00e0y, nh\u01b0ng m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n v\u1eabn c\u00f3 th\u1ec3 b\u1ecb s\u01b0ng m\u1eaft c\u00e1 ch\u00e2n do Amlodipin.<\/p>\n<p>Ngo\u00e0i ra c\u00f3 th\u1ec3 g\u1eb7p: Nh\u1ee9c \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, \u0111\u1ecf b\u1eebng m\u1eb7t, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Lithium: T\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a Lithium.<\/p>\n<p>Thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef Kali (Spironolacton), mu\u1ed1i Kali: Nguy c\u01a1 t\u0103ng Kali m\u00e1u qu\u00e1 m\u1ee9c g\u00e2y r\u1ed1i lo\u1ea1n nh\u1ecbp tim.<\/p>\n<p>Thu\u1ed1c kh\u00e1ng vi\u00eam NSAIDs (Ibuprofen, Aspirin li\u1ec1u cao): L\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a Amlessa v\u00e0 h\u1ea1i th\u1eadn.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef mang thai: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh. Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y \u00edt n\u01b0\u1edbc \u1ed1i, suy th\u1eadn v\u00e0 bi\u1ebfn d\u1ea1ng s\u1ecd m\u1eb7t \u1edf thai nhi (\u0111\u1eb7c bi\u1ec7t trong 6 th\u00e1ng cu\u1ed1i thai k\u1ef3).<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: Kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7 (do h\u1ea1 huy\u1ebft \u00e1p), do \u0111\u00f3 c\u1ea7n c\u1ea9n tr\u1ecdng khi th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c \u0111\u00f2i h\u1ecfi s\u1ef1 t\u1eadp trung cao \u0111\u1ed9.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng: H\u1ea1 huy\u1ebft \u00e1p nghi\u00eam tr\u1ecdng (cho\u00e1ng v\u00e1ng, ng\u1ea5t x\u1ec9u), nh\u1ecbp tim nhanh, r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i.<\/p>\n<p>X\u1eed tr\u00ed: \u0110\u1eb7t b\u1ec7nh nh\u00e2n n\u1eb1m ng\u1eeda, k\u00ea cao ch\u00e2n \u0111\u1ec3 m\u00e1u v\u1ec1 n\u00e3o. G\u1ecdi ngay c\u1ea5p c\u1ee9u 115 ho\u1eb7c \u0111\u01b0a \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 \u0111\u01b0\u1ee3c r\u1eeda d\u1ea1 d\u00e0y v\u00e0 b\u00f9 d\u1ecbch t\u0129nh m\u1ea1ch.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef thu\u1ed1c Amlessa 4mg\/5mg trong bao b\u00ec k\u00edn, tr\u00e1nh \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp.<\/p>\n<h2>S\u1ea3n ph\u1ea9m thay th\u1ebf thu\u1ed1c Amlessa 4mg\/5mg<\/h2>\n<p>Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Amlessa 4mg\/5mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o thu\u1ed1c <a href=\"https:\/\/trungtamthuoc.com\/beatil-4mg5mg-cong-dung-cach-dung-chong-chi-dinh\" rel=\"noopener\">Beatil 4mg\/5mg<\/a>. \u0110\u00e2y l\u00e0 s\u1ea3n ph\u1ea9m c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t (Perindopril 4mg, Amlodipin 5mg) v\u00e0 ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>William J Elliott, Evgeny A Bistrika. Perindopril arginine and amlodipine besylate for hypertension: a safety evaluation, truy c\u1eadp ng\u00e0y 25 th\u00e1ng 11 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29065722\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29065722\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Amlessa 4mg\/5mg l\u00e0 thu\u1ed1c tim m\u1ea1ch ph\u1ed1i h\u1ee3p, gi\u00fap ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p hi\u1ec7u qu\u1ea3 b\u1eb1ng c\u00e1ch k\u1ebft h\u1ee3p hai c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng kh\u00e1c nhau trong m\u1ed9t vi\u00ean thu\u1ed1c duy nh\u1ea5t.<\/p>\n","protected":false},"author":1,"featured_media":149180,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-149177","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/149177","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=149177"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/149180"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=149177"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=149177"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=149177"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}