{"id":148997,"date":"2025-11-24T09:27:18","date_gmt":"2025-11-24T02:27:18","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=148997"},"modified":"2025-11-24T09:29:11","modified_gmt":"2025-11-24T02:29:11","slug":"apeglin-400mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/apeglin-400mg\/","title":{"rendered":"Apeglin 400mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Apeglin 400mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi <\/b><b>Laboratorios Cinfa, S.A <\/b><b>c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 <\/b>840110970824<\/p>\n<h2>Apeglin 400mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <b>vi\u00ean u\u1ed1ng Apeglin 400mg<\/b> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Gabapentin\u2026\u2026400mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 g\u1ed3m: lactose khan, tinh b\u1ed9t ng\u00f4, talc v\u00e0 v\u1ecf nang c\u1ee9ng (g\u1ed3m titan dioxid, s\u1eaft oxyd v\u00e0 gelatin).<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang c\u1ee9ng<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 840110970824<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 v\u1ec9 x 15 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: T\u00e2y Ban Nha<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Apeglin 400mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Gabapentin th\u1ea5m v\u00e0o h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng v\u00e0 g\u1eafn ch\u1ecdn l\u1ecdc v\u00e0o ti\u1ec3u \u0111\u01a1n v\u1ecb \u03b12\u03b4 c\u1ee7a k\u00eanh canxi ph\u1ee5 thu\u1ed9c \u0111i\u1ec7n th\u1ebf. S\u1ef1 g\u1eafn k\u1ebft n\u00e0y l\u00e0m gi\u1ea3m gi\u1ea3i ph\u00f3ng c\u00e1c ch\u1ea5t d\u1eabn truy\u1ec1n k\u00edch th\u00edch trong n\u00e3o v\u00e0 t\u1ee7y s\u1ed1ng, t\u1eeb \u0111\u00f3 gi\u00fap \u1ed5n \u0111\u1ecbnh ho\u1ea1t \u0111\u1ed9ng \u0111i\u1ec7n b\u1ea5t th\u01b0\u1eddng g\u00e2y co gi\u1eadt v\u00e0 gi\u1ea3m m\u1ee9c \u0111\u1ed9 d\u1eabn truy\u1ec1n t\u00edn hi\u1ec7u \u0111au. Thu\u1ed1c kh\u00f4ng t\u00e1c \u0111\u1ed9ng l\u00ean th\u1ee5 th\u1ec3 GABA, kh\u00f4ng \u1ea3nh h\u01b0\u1edfng<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Sau u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh xu\u1ea5t hi\u1ec7n sau kho\u1ea3ng 2\u20133 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng gi\u1ea3m khi t\u0103ng li\u1ec1u v\u00e0 trung b\u00ecnh kho\u1ea3ng 60% v\u00e0 kh\u00f4ng b\u1ecb t\u00e1c \u0111\u1ed9ng b\u1edfi th\u1ee9c \u0103n.<\/p>\n<p>Ph\u00e2n b\u1ed1: Kh\u00f4ng g\u1eafn protein huy\u1ebft t\u01b0\u01a1ng, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a Apeglin kho\u1ea3ng 57,7 L, v\u00e0o \u0111\u01b0\u1ee3c d\u1ecbch n\u00e3o t\u1ee7y v\u00e0 qua \u0111\u01b0\u1ee3c s\u1eefa m\u1eb9.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: \u01a0 gan Apeglin h\u1ea7u nh\u01b0 kh\u00f4ng b\u1ecb chuy\u1ec3n ho\u00e1<\/p>\n<p>Th\u1ea3i tr\u1eeb: Nguy\u00ean d\u1ea1ng qua th\u1eadn v\u1edbi chu tr\u00ecnh b\u00e1n hu\u1ef7 l\u00e0 5\u20137 gi\u1edd. Ng\u01b0\u1eddi cao tu\u1ed5i v\u00e0 ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn gi\u1ea3m c\u00f3 gi\u1ea3m thanh th\u1ea3i. Thu\u1ed1c \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf b\u1eb1ng th\u1ea9m ph\u00e2n m\u00e1u.<\/p>\n<h2>Thu\u1ed1c Apeglin 400mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>1. \u0110\u1ed9ng kinh<\/p>\n<p>D\u00f9ng b\u1ed5 tr\u1ee3 \u0111\u1ec3 ki\u1ec3m so\u00e1t c\u01a1n co gi\u1eadt c\u1ee5c b\u1ed9 c\u00f3 ho\u1eb7c kh\u00f4ng k\u00e8m lan t\u1ecfa th\u1ee9 ph\u00e1t \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb t\u1eeb 6 tu\u1ed5i tr\u1edf l\u00ean.<\/p>\n<p>D\u00f9ng \u0111\u01a1n tr\u1ecb \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 thanh thi\u1ebfu ni\u00ean t\u1eeb 12 tu\u1ed5i b\u1ecb co gi\u1eadt c\u1ee5c b\u1ed9 c\u00f3 ho\u1eb7c kh\u00f4ng k\u00e8m lan t\u1ecfa th\u1ee9 ph\u00e1t.<\/p>\n<p>2. \u0110au th\u1ea7n kinh ngo\u1ea1i bi\u00ean<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb \u0111au th\u1ea7n kinh do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb \u0111au d\u00e2y th\u1ea7n kinh sau zona \u1edf ng\u01b0\u1eddi l\u1edbn.<\/p>\n<figure id=\"attachment_149017\" aria-describedby=\"caption-attachment-149017\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-149017\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Apeglin-400mg.jpg\" alt=\"Apeglin 400mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Apeglin-400mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Apeglin-400mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Apeglin-400mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Apeglin-400mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Apeglin-400mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-149017\" class=\"wp-caption-text\">Thu\u1ed1c Apeglin 400mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb co gi\u1eadt c\u1ee5c b\u1ed9<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u d\u00f9ng chu\u1ea9n cho ng\u01b0\u1eddi t\u1eeb 12 tu\u1ed5i \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o nh\u01b0 sau<\/p>\n<p>Ng\u00e0y 1: 300mg Gabapentin\/l\u1ea7n<\/p>\n<p>Ng\u00e0y 2: 300mg Gabapentin d\u00f9ng 2 l\u1ea7n<\/p>\n<p>Ng\u00e0y 3: 300mg Gabapentin d\u00f9ng 3 l\u1ea7n<\/p>\n<p>Khi ng\u1eebng thu\u1ed1c: gi\u1ea3m li\u1ec1u d\u1ea7n trong \u2265 1 tu\u1ea7n, tr\u00e1nh ng\u1eebng \u0111\u1ed9t ng\u1ed9t<\/p>\n<p><b>\u0110i\u1ec1u tr\u1ecb \u0111\u1ed9ng kinh<\/b><\/p>\n<p><em><strong>Ng\u01b0\u1eddi l\u1edbn &amp; tr\u1ebb \u2265 12 tu\u1ed5i:<\/strong><\/em> Li\u1ec1u d\u00f9ng t\u1ed5ng trong 1 ng\u00e0y l\u00e0 900mg &#8211; 9 vi\u00ean, chia 3 l\u1ea7n.<\/p>\n<p>C\u00f3 th\u1ec3:<\/p>\n<ul>\n<li>Chu\u1ea9n \u0111\u1ed9 theo l\u1ecbch: 300 mg ng\u00e0y 1 \u2192 2 l\u1ea7n ng\u00e0y 2 \u2192 3 l\u1ea7n ng\u00e0y 3, ho\u1eb7c Kh\u1edfi \u0111\u1ea7u tr\u1ef1c ti\u1ebfp v\u1edbi 300 mg \u00d7 3 l\u1ea7n\/ng\u00e0y.<\/li>\n<li>N\u1ebfu \u0111\u00e1p \u1ee9ng ch\u01b0a \u0111\u1ea1t, t\u0103ng th\u00eam 300mg\/ng\u00e0y m\u1ed7i 2\u20133 ng\u00e0y cho \u0111\u1ebfn t\u1ed1i \u0111a 3600mg\/ng\u00e0y (12 vi\u00ean\/ng\u00e0y).<\/li>\n<\/ul>\n<p>Th\u1eddi gian th\u01b0\u1eddng c\u1ea7n \u0111\u1ec3 \u0111\u1ea1t c\u00e1c m\u1ee9c li\u1ec1u:<\/p>\n<ul>\n<li>1800mg\/ng\u00e0y (6 vi\u00ean\/ng\u00e0y): ~1 tu\u1ea7n<\/li>\n<li>2400mg\/ng\u00e0y (8 vi\u00ean\/ng\u00e0y): ~2 tu\u1ea7n<\/li>\n<li>3600mg\/ng\u00e0y (12 vi\u00ean\/ng\u00e0y): ~3 tu\u1ea7n<\/li>\n<\/ul>\n<p>M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p c\u00f3 th\u1ec3 dung n\u1ea1p t\u1edbi 4800mg\/ng\u00e0y (16 vi\u00ean 300mg).<\/p>\n<p>Kho\u1ea3ng c\u00e1ch c\u00e1c li\u1ec1u kh\u00f4ng qu\u00e1 12 gi\u1edd \u0111\u1ec3 gi\u1eef n\u1ed3ng \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh.<\/p>\n<p><em><strong>Tr\u1ebb 6\u2013&lt;12 tu\u1ed5i:<\/strong><\/em><\/p>\n<p>Kh\u1edfi \u0111\u1ea7u: 10\u201315mg\/kg\/ng\u00e0y.<\/p>\n<p>T\u0103ng d\u1ea7n trong 3 ng\u00e0y \u0111\u1ea1t li\u1ec1u \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Li\u1ec1u duy tr\u00ec: 25\u201335mg\/kg\/ng\u00e0y (t\u1ed1i \u0111a 50mg\/kg\/ng\u00e0y), chia 3 l\u1ea7n.<\/p>\n<p>Kh\u00f4ng c\u1ea7n \u0111o n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u \u0111\u1ec3 ch\u1ec9nh li\u1ec1u<\/p>\n<p><strong>\u0110i\u1ec1u tr\u1ecb \u0111au th\u1ea7n kinh ngo\u1ea1i bi\u00ean (ng\u01b0\u1eddi l\u1edbn)<\/strong><\/p>\n<p>C\u00f3 th\u1ec3 chu\u1ea9n nh\u01b0 tr\u00ean ho\u1eb7c b\u1eaft \u0111\u1ea7u tr\u1ef1c ti\u1ebfp v\u1edbi 900mg\/ng\u00e0y = 300mg \u00d7 3 l\u1ea7n.<\/p>\n<p>T\u0103ng th\u00eam 300mg\/ng\u00e0y (1 vi\u00ean) m\u1ed7i 2\u20133 ng\u00e0y t\u00f9y \u0111\u00e1p \u1ee9ng, t\u1ed1i \u0111a 3600mg\/ng\u00e0y (12 vi\u00ean\/ng\u00e0y).<\/p>\n<p>Th\u1eddi gian \u0111\u1ea1t c\u00e1c m\u1ee9c li\u1ec1u th\u01b0\u1eddng:<\/p>\n<ul>\n<li>1800mg\/ng\u00e0y (6 vi\u00ean): 1 tu\u1ea7n<\/li>\n<li>2400mg\/ng\u00e0y (8 vi\u00ean): 2 tu\u1ea7n<\/li>\n<li>3600mg\/ng\u00e0y (12 vi\u00ean): 3 tu\u1ea7n<\/li>\n<\/ul>\n<p>D\u1eef li\u1ec7u hi\u1ec7u qu\u1ea3 \u2013 an to\u00e0n ch\u1ee7 y\u1ebfu \u0111\u1ebfn 5 th\u00e1ng \u0111i\u1ec1u tr\u1ecb; d\u00f9ng d\u00e0i h\u01a1n c\u1ea7n \u0111\u00e1nh gi\u00e1 l\u1ea1i.<\/p>\n<p><strong>Nh\u00f3m \u0111\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t<\/strong><\/p>\n<p>Th\u1ec3 tr\u1ea1ng y\u1ebfu, s\u1ee9c kh\u1ecfe k\u00e9m: T\u0103ng li\u1ec1u ch\u1eadm h\u01a1n, gi\u1ea3m m\u1ee9c t\u0103ng m\u1ed7i l\u1ea7n.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i: Th\u01b0\u1eddng ph\u1ea3i gi\u1ea3m li\u1ec1u do gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn; d\u1ec5 g\u1eb7p bu\u1ed3n ng\u1ee7, m\u1ec7t, ph\u00f9.<\/p>\n<p>Suy th\u1eadn: C\u1ea7n ch\u1ec9nh li\u1ec1u theo \u0111\u1ed9 l\u1ecdc c\u1ea7u th\u1eadn; d\u00f9ng theo ch\u1ec9 \u0111\u1ecbnh b\u00e1c s\u0129.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p><strong>Vi\u00ean nang Apeglin 400mg<\/strong> \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, trong ho\u1eb7c sau \u0103n nh\u01b0ng l\u01b0u \u00fd c\u1ea7n d\u00f9ng nguy\u00ean c\u1ea3 vi\u00ean, tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng t\u00e1ch vi\u00ean tr\u1eeb khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Apeglin 400mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi gabapentin v\u00e0 t\u00e1 d\u01b0\u1ee3c c\u00f3 trong Apeglin 400mg<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>H\u1ed9i ch\u1ee9ng Stevens\u2013Johnson (SJS), DRESS hay ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c (TEN), n\u1ebfu xu\u1ea5t hi\u1ec7n ph\u00e1t ban k\u00e8m s\u1ed1t, s\u01b0ng h\u1ea1ch hay d\u1ea5u hi\u1ec7u to\u00e0n th\u00e2n \u2192 ng\u01b0ng thu\u1ed1c ngay.<\/p>\n<p>Kh\u00f4ng t\u00e1i s\u1eed d\u1ee5ng thu\u1ed1c \u1edf nh\u1eefng ng\u01b0\u1eddi t\u1eebng g\u1eb7p ph\u1ea3n \u1ee9ng da nghi\u00eam tr\u1ecdng.<\/p>\n<p>Thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh, bao g\u1ed3m gabapentin, c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 \u00fd ngh\u0129 ho\u1eb7c h\u00e0nh vi t\u1ef1 s\u00e1t \u2192 c\u1ea7n theo d\u00f5i k\u1ef9.<\/p>\n<p>Hi\u1ebfm g\u1eb7p ph\u1ea3n v\u1ec7: kh\u00f3 th\u1edf, ph\u00f9 m\u1eb7t, t\u1ee5t huy\u1ebft \u00e1p.<\/p>\n<p>\u0110au b\u1ee5ng d\u1eef d\u1ed9i ho\u1eb7c n\u00f4n \u00f3i \u2192 \u0111\u00e1nh gi\u00e1 l\u1ea1i vi\u1ec7c d\u00f9ng thu\u1ed1c.<\/p>\n<p>Ng\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t c\u00f3 th\u1ec3 g\u00e2y co gi\u1eadt b\u00f9ng ph\u00e1t \u2192 gi\u1ea3m li\u1ec1u t\u1eeb t\u1eeb \u00edt nh\u1ea5t 1 tu\u1ea7n.<\/p>\n<p>C\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7, an th\u1ea7n; nguy c\u01a1 cao h\u01a1n khi ph\u1ed1i h\u1ee3p thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng (v\u00ed d\u1ee5 morphin).<\/p>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 \u1ea3nh h\u01b0\u1edfng l\u00e2u d\u00e0i c\u1ee7a gabapentin l\u00ean ph\u00e1t tri\u1ec3n tr\u00ed tu\u1ec7 v\u00e0 kh\u1ea3 n\u0103ng h\u1ecdc t\u1eadp \u1edf tr\u1ebb nh\u1ecf<\/p>\n<p>C\u00f3 kh\u1ea3 n\u0103ng g\u00e2y l\u1ec7 thu\u1ed9c \u1edf ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed l\u1ea1m d\u1ee5ng ch\u1ea5t.<\/p>\n<p>C\u00f3 th\u1ec3 g\u00e2y run, m\u1ea5t ng\u1ee7, \u0111au \u0111\u1ea7u, lo \u00e2u n\u1ebfu ng\u1eebng d\u00f9ng vi\u00ean nang Apeglin 400mg m\u1ed9t c\u00e1ch \u0111\u1ed9t ng\u1ed9t<\/p>\n<p>C\u00f3 th\u1ec3 g\u00e2y d\u01b0\u01a1ng t\u00ednh gi\u1ea3 khi th\u1eed protein ni\u1ec7u b\u1eb1ng que nh\u00fang.<\/p>\n<p>Kh\u00f4ng d\u00f9ng Apeglin 400mg cho ng\u01b0\u1eddi kh\u00f4ng dung n\u1ea1p lactose<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, gi\u1ea3m ph\u1ed1i h\u1ee3p v\u1eadn \u0111\u1ed9ng; k\u00e8m m\u1ec7t m\u1ecfi, s\u1ed1t.<\/p>\n<p>Nhi\u1ec5m tr\u00f9ng c\u00f3 th\u1ec3 x\u1ea3y ra: vi\u00eam h\u00f4 h\u1ea5p, vi\u00eam tai gi\u1eefa, nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u; \u0111\u00f4i khi gi\u1ea3m b\u1ea1ch c\u1ea7u, t\u0103ng c\u00e2n.<\/p>\n<p>R\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n \u2013 th\u1ea7n kinh: tr\u1ea7m c\u1ea3m, lo \u00e2u, b\u1ed1i r\u1ed1i; thay \u0111\u1ed5i c\u1ea3m gi\u00e1c th\u00e8m \u0103n; t\u0103ng huy\u1ebft \u00e1p, kh\u00f3 th\u1edf, vi\u00eam h\u1ecdng.<\/p>\n<p>R\u1ed1i lo\u1ea1n ti\u00eau ho\u00e1: \u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n, t\u00e1o b\u00f3n ho\u1eb7c ti\u00eau ch\u1ea3y.<\/p>\n<p>D\u1ecb \u1ee9ng da: ph\u00e1t ban, ng\u1ee9a, ph\u00f9 m\u1eb7t; r\u1ea5t hi\u1ebfm nh\u01b0ng c\u00f3 th\u1ec3 g\u1eb7p SJS, TEN, ph\u00f9 m\u1ea1ch.<\/p>\n<p>\u00cdt g\u1eb7p nh\u01b0ng n\u1eb7ng: vi\u00eam gan, suy th\u1eadn c\u1ea5p, ti\u00eau c\u01a1 v\u00e2n, \u1ee9c ch\u1ebf h\u00f4 h\u1ea5p, m\u00faa gi\u1eadt\u2013lo\u1ea1n tr\u01b0\u01a1ng l\u1ef1c, \u1ea3o gi\u00e1c, r\u1ed1i lo\u1ea1n t\u00ecnh d\u1ee5c.<\/p>\n<p>Sau l\u01b0u h\u00e0nh: ghi nh\u1eadn h\u1ed9i ch\u1ee9ng cai thu\u1ed1c v\u00e0 m\u1ed9t s\u1ed1 ca t\u1eed vong \u0111\u1ed9t ng\u1ed9t.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>T\u0103ng nguy c\u01a1 \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng khi d\u00f9ng c\u00f9ng thu\u1ed1c an th\u1ea7n, \u0111\u1eb7c bi\u1ec7t opioid \u2192 c\u00f3 th\u1ec3 g\u00e2y ng\u1ee7 s\u00e2u, gi\u1ea3m th\u00f4ng kh\u00ed, th\u1eadm ch\u00ed t\u1eed vong.<\/p>\n<p>Morphin d\u00f9ng tr\u01b0\u1edbc gabapentin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng AUC gabapentin ~44% \u2192 c\u1ea7n theo d\u00f5i v\u00e0 c\u00e2n nh\u1eafc gi\u1ea3m li\u1ec1u.<\/p>\n<p>Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn phenytoin, carbamazepin, valproat, phenobarbital ho\u1eb7c thu\u1ed1c tr\u00e1nh thai (ethinyl estradiol, norethindron).<\/p>\n<p>Thu\u1ed1c kh\u00e1ng acid ch\u1ee9a nh\u00f4m\/magnesi gi\u1ea3m sinh kh\u1ea3 d\u1ee5ng ~25% \u2192 u\u1ed1ng c\u00e1ch nhau t\u1ed1i thi\u1ec3u 2 gi\u1edd.<\/p>\n<p>Probenecid kh\u00f4ng \u1ea3nh h\u01b0\u1edfng th\u1ea3i tr\u1eeb; cimetidin ch\u1ec9 gi\u1ea3m nh\u1eb9 b\u00e0i ti\u1ebft qua th\u1eadn, kh\u00f4ng quan tr\u1ecdng v\u1ec1 l\u00e2m s\u00e0ng.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh n\u00f3i chung t\u0103ng nguy c\u01a1 d\u1ecb t\u1eadt (s\u1ee9t m\u00f4i, b\u1ea5t th\u01b0\u1eddng tim, d\u1ecb t\u1eadt \u1ed1ng th\u1ea7n kinh), \u0111\u1eb7c bi\u1ec7t khi ph\u1ed1i h\u1ee3p nhi\u1ec1u thu\u1ed1c \u2192 \u01b0u ti\u00ean \u0111\u01a1n tr\u1ecb li\u1ec7u.<\/p>\n<p>Ng\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t c\u00f3 th\u1ec3 g\u00e2y c\u01a1n co gi\u1eadt nguy hi\u1ec3m cho m\u1eb9 v\u00e0 thai.<\/p>\n<p>Gabapentin qua \u0111\u01b0\u1ee3c nhau thai; d\u1eef li\u1ec7u tr\u00ean thai k\u1ef3 c\u00f2n h\u1ea1n ch\u1ebf \u2192 ch\u1ec9 d\u00f9ng khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1.<\/p>\n<p>C\u00f3 b\u00e1o c\u00e1o h\u1ed9i ch\u1ee9ng cai \u1edf tr\u1ebb s\u01a1 sinh (nguy c\u01a1 cao h\u01a1n khi ph\u1ed1i h\u1ee3p opioid) \u2192 c\u1ea7n theo d\u00f5i sau sinh.<\/p>\n<p>Thu\u1ed1c b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9; ch\u1ec9 d\u00f9ng khi c\u1ea7n thi\u1ebft v\u00e0 theo d\u00f5i tr\u1ebb. Kh\u00f4ng ghi nh\u1eadn \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng sinh s\u1ea3n trong nghi\u00ean c\u1ee9u \u0111\u1ed9ng v\u1eadt.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, gi\u1ea3m t\u1eadp trung v\u00e0 ph\u1ed1i h\u1ee3p \u0111\u1ed9ng t\u00e1c l\u00e0m t\u0103ng nguy c\u01a1 tai n\u1ea1n. \u0110\u1eb7c bi\u1ec7t cao nh\u1ea5t khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb ho\u1eb7c t\u0103ng li\u1ec1u. Ch\u1ec9 l\u00e1i xe\/m\u00e1y m\u00f3c khi ch\u1eafc ch\u1eafn thu\u1ed1c kh\u00f4ng c\u00f2n g\u00e2y \u1ea3nh h\u01b0\u1edfng.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u l\u1edbn (t\u1edbi 49 g) th\u01b0\u1eddng kh\u00f4ng g\u00e2y \u0111\u1ed9c t\u00ednh \u0111e d\u1ecda t\u00ednh m\u1ea1ng; c\u00f3 th\u1ec3 ch\u00f3ng m\u1eb7t, nh\u00ecn \u0111\u00f4i, ng\u1ee7 g\u00e0, n\u00f3i kh\u00f3, th\u1edd \u01a1 ho\u1eb7c r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a nh\u1eb9 \u2192 h\u1ed3i ph\u1ee5c v\u1edbi \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3.<\/p>\n<p>D\u00f9ng k\u00e8m thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng c\u00f3 th\u1ec3 g\u00e2y h\u00f4n m\u00ea.<\/p>\n<p>Ch\u1ea1y th\u1eadn gi\u00fap lo\u1ea1i b\u1ecf thu\u1ed1c, h\u1eefu \u00edch \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng; ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng th\u01b0\u1eddng kh\u00f4ng c\u1ea7n.<\/p>\n<p>D\u1eef li\u1ec7u \u0111\u1ed9ng v\u1eadt cho th\u1ea5y li\u1ec1u g\u00e2y ch\u1ebft r\u1ea5t cao, v\u1edbi bi\u1ec3u hi\u1ec7n gi\u1ea3m v\u1eadn \u0111\u1ed9ng, kh\u00f3 th\u1edf, m\u1ea5t ph\u1ed1i h\u1ee3p.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Apeglin 400mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Apeglin 400mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Apeglin 400mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Apeglin 400mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/galamento-400\/\">Galamento 400<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Gabapentin 400mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH BRV Healthcare, \u0111i\u1ec1u tr\u1ecb \u0111\u1ed9ng kinh c\u1ee5c b\u1ed9<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/thuoc-savi-gabapentin-300\/\">Savi Gabapentin 300<\/a> l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb c\u00e1c c\u01a1n \u0111\u1ed9ng kinh c\u1ee5c b\u1ed9, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m SaVi \u2013 Savipharm.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Taylor CP (1997). Mechanisms of action of gabapentin. Rev Neurol (Paris). Truy c\u1eadp ng\u00e0y 24 th\u00e1ng 11 n\u0103m 2025 t\u1eeb: <a style=\"font-size: 14.4px;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9686247\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/9686247\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Apeglin 400mg l\u00e0 thu\u1ed1c thu\u1ed9c nh\u00f3m ch\u1ed1ng \u0111\u1ed9ng kinh ch\u1ee9a ho\u1ea1t ch\u1ea5t gabapentin, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong ki\u1ec3m so\u00e1t c\u01a1n co gi\u1eadt c\u1ee5c b\u1ed9 v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111au th\u1ea7n kinh ngo\u1ea1i bi\u00ean.<\/p>\n","protected":false},"author":1,"featured_media":149018,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-148997","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/148997","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=148997"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/149018"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=148997"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=148997"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=148997"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}