{"id":148705,"date":"2025-11-25T11:12:14","date_gmt":"2025-11-25T04:12:14","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=148705"},"modified":"2025-11-25T11:26:57","modified_gmt":"2025-11-25T04:26:57","slug":"glumerif-4","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/glumerif-4\/","title":{"rendered":"Glumerif 4"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<a href=\"https:\/\/vnras.com\/drug\/glumerif-4\/\"> Glumerif 4<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 Ph\u1ea7n D\u01b0\u1ee3c H\u1eadu Giang &#8211; Chi nh\u00e1nh nh\u00e0 m\u00e1y d\u01b0\u1ee3c ph\u1ea9m DHG t\u1ea1i H\u1eadu Giang, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-22032-14.<\/strong><\/p>\n<h2>Glumerif 4 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Glumerif 4<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Glimepirid 4mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-22032-14<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Glumerif 4<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Glimepirid k\u00edch th\u00edch qu\u00e1 tr\u00ecnh ti\u1ebft insulin t\u1eeb t\u1ebf b\u00e0o beta tuy\u1ebfn t\u1ee5y, c\u1ea3i thi\u1ec7n m\u1ee9c \u0111\u1ed9 nh\u1ea1y c\u1ea3m \u1edf m\u00f4 ngo\u1ea1i vi v\u1edbi insulin, t\u0103ng c\u01b0\u1eddng h\u1ea5p thu glucose \u1edf ngo\u1ea1i vi, l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<p>Ngo\u00e0i ra, c\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Glimepirid c\u00f2n li\u00ean quan \u0111\u1ebfn vi\u1ec7c gi\u1ea3m s\u1ef1 thu n\u1ea1p insulin \u1edf gan, t\u0103ng s\u1ed1 l\u01b0\u1ee3ng ch\u1ea5t v\u1eadn chuy\u1ec3n glucose ch\u1ee7 \u0111\u1ed9ng qua m\u00e0ng t\u1ebf b\u00e0o c\u01a1 v\u00e0 t\u1ebf b\u00e0o m\u1ee1, t\u0103ng thu n\u1ea1p glucose v\u00e0o m\u00f4 c\u01a1 \u2013 m\u00f4 m\u1ee1; t\u0103ng c\u01b0\u1eddng chuy\u1ec3n h\u00f3a glucose.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Glimepirid h\u1ea5p thu ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng u\u1ed1ng sau 1 gi\u1edd s\u1eed d\u1ee5ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh t\u0103ng 12% v\u00e0 AUC gi\u1ea3m 8-9% khi d\u00f9ng thu\u1ed1c c\u00f9ng b\u1eef \u0103m.<\/p>\n<p>Ph\u00e2n b\u1ed1: Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a Glimepirid khaorng 8,8L khi d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam t\u0129nh m\u1ea1ch, t\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 99,5%.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Glimepirid chuy\u1ec3n h\u00f3a t\u1ea1i gan t\u1ea1o th\u00e0nh d\u1eabn xu\u1ea5t cyclohexyl hydroxymethyl (M1), d\u1eabn xu\u1ea5t carboxyl (M2), kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh<\/p>\n<p>Th\u1ea3i tr\u1eeb: Thu\u1ed1c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n, th\u1eddi gian T \u00bd kho\u1ea3ng 5-8 gi\u1edd v\u00e0 c\u00f3 xu h\u01b0\u1edbng t\u0103ng l\u00ean 9 gi\u1edd khi d\u00f9ng nhi\u1ec1u li\u1ec1u li\u00ean t\u1ee5c.<\/p>\n<h2>Thu\u1ed1c Glumerif 4 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c <strong>Glumerif 4<\/strong> \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2 kh\u00f4ng ph\u1ee5 thu\u1ed9c insulin<\/p>\n<figure id=\"attachment_149117\" aria-describedby=\"caption-attachment-149117\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-149117\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Glumerif-4.jpg\" alt=\"Thu\u1ed1c Glumerif 4 \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2 \u1edf ng\u01b0\u1eddi l\u1edbn\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Glumerif-4.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Glumerif-4-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Glumerif-4-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Glumerif-4-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Glumerif-4-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-149117\" class=\"wp-caption-text\">Thu\u1ed1c Glumerif 4 \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2 \u1edf ng\u01b0\u1eddi l\u1edbn<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Glumerif 4<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u: 1 mg\/ng\u00e0y. T\u00f9y theo \u0111\u00e1p \u1ee9ng v\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng b\u1ec7nh c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh, c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u sau m\u1ed7i 1-2 tu\u1ea7n theo l\u1ed9 tr\u00ecnh 1mg, 2mg, 3mg, 4mg, 6mg, 8mg<\/p>\n<p>Li\u1ec1u duy tr\u00ec khuy\u1ebfn c\u00e1o t\u1eeb 1 \u0111\u1ebfn 4 mg m\u1ed7i ng\u00e0y<\/p>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c Glumerif 4 d\u1ea1ng vi\u00ean n\u00e9n, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng. Khuy\u1ebfn c\u00e1o d\u00f9ng thu\u1ed1c tr\u01b0\u1edbc b\u1eefa \u0103n s\u00e1ng ho\u1eb7c tr\u01b0\u1edbc b\u1eefa ch\u00ednh \u0111\u1ea7u ti\u00ean trong ng\u00e0y.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Glumerif 4 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Glumerif 4 cho b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 1, nhi\u1ec5m acid ceton; h\u00f4n m\u00ea, ti\u1ec1n h\u00f4n m\u00ea do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng; nhi\u1ec5m tr\u00f9ng nghi\u00eam tr\u1ecdng; m\u1eabn c\u1ea3m v\u1edbi ho\u1ea1t ch\u1ea5t + t\u00e1 d\u01b0\u1ee3c thu\u1ed1c; m\u1eabn c\u1ea3m v\u1edbi thu\u1ed1c nh\u00f3m sulfonamide kh\u00e1c; b\u1ec7nh nh\u00e2n suy gan th\u1eadn nghi\u00eam tr\u1ecdng.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Glumerif 4<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng Glumerif 4 cho ng\u01b0\u1eddi cao tu\u1ed5i, suy dinh d\u01b0\u1ee1ng, suy th\u01b0\u1ee3ng th\u1eadn, suy gan, suy th\u1eadn, suy tuy\u1ebfn y\u00ean, do t\u0103ng nguy c\u01a1 t\u1ee5t \u0111\u01b0\u1eddng huy\u1ebft<\/li>\n<li>C\u00e2n nh\u1eafc khi d\u00f9ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n m\u1edbi ph\u1eabu thu\u1eadt, nhi\u1ec5m khu\u1ea9n, s\u1ed1t cao k\u00e9o d\u00e0i, ch\u1ea5n th\u01b0\u01a1ng, stress, do m\u1ea5t ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft<\/li>\n<li>Kh\u00f4ng d\u00f9ng Glumerif 4 khi h\u1ebft h\u1ea1n s\u1eed d\u1ee5ng v\u00e0 vi\u00ean c\u00f3 d\u1ea5u hi\u1ec7u h\u01b0 h\u1ecfng<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>C\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng Glumerif 4: nh\u1ee9c \u0111\u1ea7u, hoa m\u1eaft, ch\u00f3ng m\u1eb7t, bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y, \u0111au b\u1ee5ng, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, t\u0103ng men gan, vi\u00eam gan, v\u00e0ng da, m\u1ec1 \u0111ay, ng\u1ee9a, d\u1ecb \u1ee9ng, m\u1eabn c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng,\u2026<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi Glumerif 4 v\u1edbi insulin, thu\u1ed1c ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng kh\u00e1c, coumarin, chloramphenicol, thu\u1ed1c \u1ee9c ch\u1ebf MAO, NSAID, thu\u1ed1c kh\u00e1ng n\u1ea5m, probenecid, thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n, kh\u00e1ng sinh tetracyclin,.. l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft<\/li>\n<li>S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi Glumerif 4 v\u1edbi thu\u1ed1c l\u1ee3i ti\u1ec3u thiazid, corticoid, glucagon, estrogen, phenothiazine, phenytoin,\u2026 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Glumerif 4 cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c Glumerif 4 c\u00f3 th\u1ec3 g\u00e2y t\u1ee5t \u0111\u01b0\u1eddng huy\u1ebft, th\u1eadn tr\u1ecdng khi d\u00f9ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>S\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u Glumerif 4 g\u00e2y t\u1ee5t \u0111\u01b0\u1eddng huy\u1ebft (tri\u1ec7u ch\u1ee9ng cao huy\u1ebft \u00e1p, ni\u00eam m\u1ea1c xanh xao, m\u1ec7t m\u1ecfi, v\u00e3 m\u1ed3 h\u00f4i, l\u00fa l\u1eabn, h\u00f4n m\u00ea,\u2026)<\/p>\n<p>X\u1eed tr\u00ed: b\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c cho u\u1ed1ng glucose v\u00e0 theo d\u00f5i n\u1ed3ng \u0111\u1ed9 glucose huy\u1ebft. Trong tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng c\u00f3 th\u1ec3 c\u1ea7n d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam t\u0129nh m\u1ea1ch.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Khuy\u1ebfn kh\u00edch b\u1ea3o qu\u1ea3n Glumerif 4 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30 \u0111\u1ed9 C, kh\u00f4ng ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp v\u1edbi \u00e1nh s\u00e1ng c\u01b0\u1eddng \u0111\u1ed9 cao. N\u00ean \u0111\u1ec3 s\u1ea3n ph\u1ea9m c\u00e1ch xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Glumerif 4 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/diaprid-4\/\">Diaprid 4<\/a> s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng Ty C\u1ed5 Ph\u1ea7n Pymepharco, c\u00f3 th\u00e0nh ph\u1ea7n Glimepirid 4mg, \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng typ 2<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/glimepiride-stella-4mg\/\">Glimepiride Stella 4mg<\/a> s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm \u2013 Chi nh\u00e1nh 1, c\u00f3 th\u00e0nh ph\u1ea7n Glimepirid 4mg, \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng typ 2<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Glumerif 4 do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file t<a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/HDSD-Glumerif-4-vnras.pdf\">\u1ea1i \u0111\u00e2y<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Glumerif 4 s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 Ph\u1ea7n D\u01b0\u1ee3c H\u1eadu Giang &#8211; Chi nh\u00e1nh nh\u00e0 m\u00e1y d\u01b0\u1ee3c ph\u1ea9m DHG t\u1ea1i H\u1eadu Giang, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2 kh\u00f4ng ph\u1ee5 thu\u1ed9c insulin<\/p>\n","protected":false},"author":1,"featured_media":149119,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-148705","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/148705","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=148705"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/149119"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=148705"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=148705"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=148705"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}