{"id":148703,"date":"2025-11-25T11:12:29","date_gmt":"2025-11-25T04:12:29","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=148703"},"modified":"2025-11-25T11:27:32","modified_gmt":"2025-11-25T04:27:32","slug":"givet-10","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/givet-10\/","title":{"rendered":"Givet-10"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/givet-10\/\">Givet-10<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi<\/strong> <strong>C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa (Davipharm), c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110021000 (S\u0110K c\u0169: VD-28459-17)<\/strong><\/p>\n<h2>Givet-10 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Givet-10<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Montelukast natri t\u01b0\u01a1ng \u0111\u01b0\u01a1ng montelukast 10mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110021000 (S\u0110K c\u0169: VD-28459-17)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 4 v\u1ec9 x 7 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Givet-10<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Montelukast thu\u1ed9c nh\u00f3m ch\u1ea5t \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 leukotriene. Trong c\u01a1 th\u1ec3, c\u00e1c cysteinyl leukotriene bao g\u1ed3m LTC4, LTD4, LTE4 \u0111\u01b0\u1ee3c ti\u1ebft ra t\u1eeb nhi\u1ec1u lo\u1ea1i t\u1ebf b\u00e0o, c\u00f3 hi\u1ec7u l\u1ef1c d\u01b0\u1ee1ng b\u00e0o v\u00e0 b\u1ea1ch c\u1ea7u \u01b0a eosin- l\u00e0 c\u00e1c ch\u1ea5t trung gian ti\u1ec1n hen. Ch\u00fang g\u0103n v\u00e0o c\u00e1c th\u1ee5 th\u1ec3 CysLT1 \u1edf \u0111\u01b0\u1eddng th\u1edf, g\u00e2y ra hen v\u00e0 vi\u00eam m\u0169i d\u1ecb \u1ee9ng.<\/p>\n<p>Montelukast \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng c\u00f3 ho\u1ea1t t\u00ednh ch\u1ed1ng vi\u00eam, c\u1ea3i thi\u1ec7n tri\u1ec7u ch\u1ee9ng hen, c\u00f3 \u00e1i l\u1ef1c cao v\u00e0 ch\u1ecdn l\u1ecdc v\u1edbi th\u1ee5 th\u1ec3 CysLT, \u1ee9c ch\u1ebf m\u1ea1nh t\u00e1c d\u1ee5ng c\u1ee7a LTC4, LTD4, LTE4.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Montelukast h\u1ea5p thu nhanh ch\u00f3ng v\u00e0 ho\u00e0n to\u00e0n khi d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh ghi nh\u1eadn sau 3 gi\u1edd khi d\u00f9ng li\u1ec1u 10mg, l\u00fac \u0111\u00f3i. Sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng kho\u1ea3ng 64% v\u00e0 kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi s\u1ef1 c\u00f3 m\u1eb7t c\u1ee7a th\u1ee9c \u0103n. C\u00e1c nghi\u00ean c\u1ee9u tr\u00ean chu\u1ed9t cho th\u1ea5y Montelukast c\u00f3 th\u1ec3 qua h\u00e0ng r\u00e0o m\u00e1u n\u00e3o, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 t\u1eeb 8 \u0111\u1ebfn 11L, t\u1ef7 l\u1ec7 li\u00ean k\u1ebft protein huy\u1ebft t\u01b0\u01a1ng cao, &gt; 99%. Montelukast chuy\u1ec3n h\u00f3a m\u1ea1nh m\u1ebd trong c\u01a1 th\u1ec3, sau \u0111\u00f3 th\u1ea3i tr\u1eeb qua ph\u00e2n v\u00e0 n\u01b0\u1edbc ti\u1ec3u. \u1ede t\u00ecnh nguy\u1ec7n vi\u00ean tr\u1ebb tu\u1ed5i, T \u00bd c\u1ee7a Montelukast kho\u1ea3ng 2,7-5,5 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Givet-10 tr\u1ecb b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c <strong>Givet-10<\/strong> \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n d\u00f9ng trong tr\u01b0\u1eddng h\u1ee3p:<\/p>\n<ul>\n<li>Ph\u00f2ng ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em &gt; 6 tu\u1ed5i<\/li>\n<li>Ph\u00f2ng ng\u1eeba tri\u1ec7u ch\u1ee9ng hen ban ng\u00e0y, ban \u0111\u00eam<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb hen do nh\u1ea1y c\u1ea3m v\u1edbi aspirin<\/li>\n<li>Ph\u00f2ng ng\u1eeba c\u01a1n co th\u1eaft ph\u1ebf qu\u1ea3n trong \u0111i\u1ec1u ki\u1ec7n g\u1eafng s\u1ee9c<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng vi\u00eam m\u0169i d\u1ecb \u1ee9ng theo m\u00f9a, vi\u00eam m\u0169i d\u1ecb \u1ee9ng quanh n\u0103m cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em &gt; 6 tu\u1ed5i<\/li>\n<\/ul>\n<figure id=\"attachment_149098\" aria-describedby=\"caption-attachment-149098\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-149098\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Givet-10.jpg\" alt=\"Thu\u1ed1c Givet-10 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng hen ban ng\u00e0y v\u00e0 ban \u0111\u00eam\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Givet-10.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Givet-10-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Givet-10-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Givet-10-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Givet-10-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-149098\" class=\"wp-caption-text\">Thu\u1ed1c Givet-10 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng hen ban ng\u00e0y v\u00e0 ban \u0111\u00eam<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Givet-10<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<table>\n<tbody>\n<tr>\n<td width=\"312\">\u0110\u1ed1i t\u01b0\u1ee3ng<\/td>\n<td width=\"312\">Li\u1ec1u d\u00f9ng<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Ng\u01b0\u1eddi l\u1edbn, tr\u1ebb em &gt; 15 tu\u1ed5i<\/td>\n<td width=\"312\">1 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Tr\u1ebb em 6-14 tu\u1ed5i<\/td>\n<td width=\"312\">1 vi\u00ean 5 mg\/ng\u00e0y<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Tr\u1ebb em 6 th\u00e1ng \u2013 5 tuoori:<\/td>\n<td width=\"312\">Chuy\u1ec3n d\u1ea1ng g\u00f3i c\u1ed1m 4 mg\/ng\u00e0y<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c Givet-10 d\u1ea1ng vi\u00ean n\u00e9n bao phim, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng, khuy\u1ebfn c\u00e1o d\u00f9ng v\u00e0o bu\u1ed5i t\u1ed1i (trong \u0111i\u1ec1u tr\u1ecb hen).<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Givet-10 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng d\u00f9ng thu\u1ed1c Givet-10 cho b\u1ec7nh nh\u1eadn m\u1eabn c\u1ea3m v\u1edbi montelukast v\u00e0 b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c kh\u00e1c trong ch\u1ebf ph\u1ea9m.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Givet-10<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>D\u1eef li\u1ec7u v\u1ec1 hi\u1ec7u qu\u1ea3 khi d\u00f9ng Givet-10 trong \u0111i\u1ec1u tr\u1ecb c\u01a1n hen c\u1ea5p t\u00ednh ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh, do \u0111\u00f3 kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng<\/li>\n<li>B\u1ec7nh nh\u00e2n \u0111ang \u0111i\u1ec1u tr\u1ecb hen v\u1edbi corticoid d\u1ea1ng h\u00edt c\u1ea7n gi\u1ea3m li\u1ec1u d\u1ea7n d\u1ea7n theo h\u01b0\u1edbng d\u1eabn c\u1ee7a b\u00e1c s\u0129<\/li>\n<li>Th\u1eadn tr\u1ecdng v\u00e0 theo d\u00f5i ch\u1eb7t ch\u1ebd khi gi\u1ea3m li\u1ec1u corticoid \u0111\u01b0\u1eddng u\u1ed1ng v\u1edbi b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb v\u1edbi montelukast<\/li>\n<li>Trong qu\u00e1 tr\u00ecnh d\u00f9ng Givet-10, b\u1ec7nh nh\u00e2n hen m\u1eabn c\u1ea3m v\u1edbi aspirin v\u1eabn tr\u00e1nh d\u00f9ng aspirin v\u00e0 NSAID kh\u00e1c.<\/li>\n<li>Thu\u1ed1c c\u00f3 ch\u1ee9a t\u00e1 d\u01b0\u1ee3c m\u00e0u, d\u1ea7u th\u1ea7u d\u1ea7u c\u00f3 th\u1ec3 g\u00e2y d\u1ecb \u1ee9ng, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c thu\u1ed1c c\u00f3 ch\u1ee9a lactose, kh\u00f4ng d\u00f9ng Givet-10 cho b\u1ec7nh nh\u00e2n m\u1eabn c\u1ea3m ho\u1eb7c k\u00e9m h\u1ea5p thu \u0111\u01b0\u1eddng<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>M\u1ed9t s\u1ed1 ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng Givet-10 bao g\u1ed3m nh\u1ee9c \u0111\u1ea7u, \u0111au b\u1ee5ng, qu\u00e1 m\u1eabn, m\u1ea5t ng\u1ee7, m\u1ed9ng du, co gi\u1eadt, ch\u1ea3y m\u00e1u cam, m\u1ec1 \u0111ay, ng\u1ee9a, t\u0103ng ch\u1ea3y m\u00e1u, gi\u1ea3m tr\u00ed nh\u1edb, \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, \u1ea3o gi\u00e1c, h\u1ed9i ch\u1ee9ng Churg-Strauss, vi\u00eam gan, h\u1ed3ng ban \u0111a d\u1ea1ng,\u2026<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Givet-10 kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a c\u00e1c thu\u1ed1c sau khi d\u00f9ng \u0111\u1ed3ng th\u1eddi: Theophylin, prednison, terfenadin, digoxin, warfarin, prednisolon, thu\u1ed1c tr\u00e1nh thai d\u1ea1ng u\u1ed1ng<\/li>\n<li>Phenobarbital l\u00e0m gi\u1ea3m AUC c\u1ee7a montelukast kho\u1ea3ng 40%, th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng<\/li>\n<li>Montelukast kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn chuy\u1ec3n h\u00f3a c\u1ee7a paclitaxel, rosiglitazon, repaglinide<\/li>\n<li>Gemfibrozil d\u00f9ng c\u00f9ng Givet-10 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u1ec9 d\u00f9ng Givet-10 cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa khi th\u1ef1c s\u1ef1 c\u1ea7n thi\u1ebft.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c Givet-10 c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, c\u00e2n nh\u1eafc d\u00f9ng trong tr\u01b0\u1eddng h\u1ee3p \u0111ang l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin c\u1ee5 th\u1ec3 v\u1ec1 qu\u00e1 li\u1ec1u Givet-10<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n Givet-10 \u1edf n\u01a1i c\u00f3 \u0111\u1ed9 \u1ea9m kh\u00f4ng qu\u00e1 70%, nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, n\u01a1i kh\u00f4 r\u00e1o, s\u1ea1ch s\u1ebd. \u0110\u1ec3 tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Givet-10 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/sandoz-montelukast-fct-10mg\/\">Sandoz Montelukast FCT 10mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Montelukast (d\u01b0\u1edbi d\u1ea1ng Montelukast natri) 10mg, s\u1ea3n xu\u1ea5t b\u1edfi Sandoz Ilac Sanayi ve Ticaret, A.S., \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/singulair-10mg-msd\/\">Singulair 10mg MSD<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Montelukast 10mg, s\u1ea3n xu\u1ea5t b\u1edfi \u00a0C\u00f4ng ty D\u01b0\u1ee3c ph\u1ea9m MSD, d\u1ef1 ph\u00f2ng c\u01a1n co th\u1eaft ph\u1ebf qu\u1ea3n do g\u1eafng s\u1ee9c.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Givet-10 do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file t<a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/HDSD-Givet-10-vnras.pdf\">\u1ea1i \u0111\u00e2y<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Givet-10 ph\u00f2ng ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em &gt; 6 tu\u1ed5i, ph\u00f2ng ng\u1eeba tri\u1ec7u ch\u1ee9ng hen ban ng\u00e0y, ban \u0111\u00eam, s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa (Davipharm)<\/p>\n","protected":false},"author":1,"featured_media":149100,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-148703","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/148703","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=148703"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/149100"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=148703"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=148703"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=148703"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}