{"id":148426,"date":"2025-11-19T11:50:11","date_gmt":"2025-11-19T04:50:11","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=148426"},"modified":"2025-11-19T11:51:23","modified_gmt":"2025-11-19T04:51:23","slug":"plendil-5mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/plendil-5mg\/","title":{"rendered":"Plendil 5mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/plendil-5mg\/\">Plendil 5mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi<\/strong> <strong>AstraZeneca AB, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-17835-14.<\/strong><\/p>\n<figure id=\"attachment_148612\" aria-describedby=\"caption-attachment-148612\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-148612\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Plendil-5mg.jpg\" alt=\"Thu\u1ed1c Plendil 5mg \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00e0 \u0111au th\u1eaft ng\u1ef1c\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Plendil-5mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Plendil-5mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Plendil-5mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Plendil-5mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Plendil-5mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-148612\" class=\"wp-caption-text\">Thu\u1ed1c Plendil 5mg \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00e0 \u0111au th\u1eaft ng\u1ef1c<\/figcaption><\/figure>\n<h2>Plendil 5mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Plendil 5mg<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Felodipine 5mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n ph\u00f3ng th\u00edch k\u00e9o d\u00e0i<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-17835-14<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Th\u1ee5y \u0110i\u1ec3n<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Plendil 5mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Felodipine thu\u1ed9c nh\u00f3m ch\u1ea5t ch\u1eb9n k\u00eanh calci, c\u00f3 t\u00ednh ch\u1ecdn l\u1ecdc cao, gi\u00fap l\u00e0m gi\u1ea3m huy\u1ebft \u00e1p \u0111\u1ed9ng m\u1ea1ch, gi\u1ea3m s\u1ee9c c\u1ea3n m\u1ea1ch m\u00e1u to\u00e0n th\u00e2n. Ho\u1ea1t ch\u1ea5t n\u00e0y c\u00f3 t\u00ednh ch\u1ecdn l\u1ecdc tr\u00ean c\u01a1 tr\u01a1n ti\u1ec3u \u0111\u1ed9ng m\u1ea1ch. S\u1eed d\u1ee5ng Felodipine \u1edf li\u1ec1u ddiefu tr\u1ecb kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn t\u00ednh co b\u00f3p v\u00e0 s\u1ef1 d\u1eabn truy\u1ec1n c\u01a1 tim. C\u00e1c nghi\u00ean c\u1ee9u cho th\u1ea5y Felodipine kh\u00f4ng g\u00e2y h\u1ea1 huy\u1ebft \u00e1p th\u1ebf \u0111\u1ee9ng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Felodipine s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng h\u1ea5p thu ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, sinh kh\u1ea3 d\u1ee5ng to\u00e0n th\u00e2n kho\u1ea3ng 15% v\u00e0 kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u l\u01b0\u1ee3ng s\u1eed d\u1ee5ng.<\/p>\n<p>Ph\u00e2n b\u1ed1: T\u1ef7 l\u1ec7 Felodipine li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 99%, ch\u1ee7 y\u1ebfu albumin<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Felodipine chuy\u1ec3n h\u00f3a ph\u1ea7n l\u1edbn \u1edf gan, c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a h\u1ea7u nh\u01b0 kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Thu\u1ed1c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u, ph\u1ea7n c\u00f2n l\u1ea1i b\u00e0i ti\u1ebft qua ph\u00e2n.<\/p>\n<h2>Thu\u1ed1c Plendil 5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c <strong>Plendil 5mg<\/strong> \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p v\u00e0 \u0111au th\u1eaft ng\u1ef1c<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Plendil 5mg<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<ul>\n<li>Li\u1ec1u \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p: li\u1ec1u kh\u1edfi \u0111\u1ea7u 5 mg\/l\u1ea7n\/ng\u00e0y; li\u1ec1u duy tr\u00ec 5-10 mg\/l\u1ea7n\/ng\u00e0y. V\u1edbi b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi cao tu\u1ed5i khuy\u1ebfn c\u00e1o d\u00f9ng li\u1ec1u 2,5 ng\/ng\u00e0y<\/li>\n<li>Li\u1ec1u \u0111i\u1ec1u tr\u1ecb \u0111au th\u1eaft ng\u1ef1c: li\u1ec1u kh\u1edfi \u0111\u1ea7u 5 mg\/l\u1ea7n\/ng\u00e0y; v\u00e0 c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u \u0111\u1ebfn 10 mg\/l\u1ea7n\/ng\u00e0y<\/li>\n<\/ul>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c Plendil 5mg d\u1ea1ng vi\u00ean n\u00e9n, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Plendil 5mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Plendil 5mg cho ng\u01b0\u1eddi qu\u00e1 m\u1eabn v\u1edbi Felodipine ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o trong thu\u1ed1c, ph\u1ee5 n\u1eef \u0111ang mang thai, b\u1ec7nh nh\u00e2n suy tim m\u1ea5t b\u00f9, nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p t\u00ednh v\u00e0 m\u1eafc ch\u1ee9ng \u0111au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Plendil 5mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c Plendil 5mg cho b\u1ec7nh nh\u00e2n thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 c\u01a1 tim do t\u0103ng nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p<\/li>\n<li>Kh\u00f4ng t\u1ef1 \u00fd thay \u0111\u1ed5i li\u1ec1u l\u01b0\u1ee3ng d\u00f9ng thu\u1ed1c tr\u1eeb khi c\u00f3 h\u01b0\u1edbng d\u1eabn c\u1ee7a b\u00e1c s\u0129<\/li>\n<li>Kh\u00f4ng d\u00f9ng thu\u1ed1c Plendil 5mg khi h\u1ebft h\u1ea1n s\u1eed d\u1ee5ng<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng Plendil 5mg: nh\u1ee9c \u0111\u1ea7u, ph\u00f9 ngo\u1ea1i bi\u00ean, cho\u00e1ng v\u00e1ng, d\u1ecb c\u1ea3m, bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng, ng\u1ee9a, m\u1ec7t m\u1ecfi, n\u00f4n m\u1eeda, \u0111au c\u01a1, \u0111au kh\u1edbp, vi\u00eam l\u1ee3i, t\u0103ng men gan, qu\u00e1 m\u1eabn, vi\u00eam m\u1ea1ch m\u00e1u do qu\u00e1 m\u1eabn.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<table>\n<tbody>\n<tr>\n<td width=\"312\">Thu\u1ed1c<\/td>\n<td width=\"312\">T\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Cimetidine, erythromycin, ketoconazole, itraconazole, flavonoid<\/td>\n<td width=\"312\">T\u0103ng n\u1ed3ng \u0111\u1ed9 Felodipine trong huy\u1ebft t\u01b0\u01a1ng<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Carbamazepine, phenytoin, barbiturate, rifampicin<\/td>\n<td width=\"312\">Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Felodipine trong huy\u1ebft t\u01b0\u01a1ng<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Tacrolimus<\/td>\n<td width=\"312\">T\u0103ng n\u1ed3ng \u0111\u1ed9 tacrolimus trong huy\u1ebft t\u01b0\u01a1ng, c\u1ea7n theo d\u00f5i n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong huy\u1ebft thanh<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Cyclosporin<\/td>\n<td width=\"312\">Kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn thu\u1ed1c khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng khuy\u00ean d\u00f9ng Plendil 5mg cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c Plendil 5mg kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u Plendil 5mg g\u00e2y t\u1ee5t huy\u1ebft \u00e1p, ch\u1eadm nh\u1ecbp tim. B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, d\u00f9ng atropine ti\u00eam t\u0129nh m\u1ea1ch.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n Plendil 5mg \u1edf n\u01a1i c\u00f3 \u0111\u1ed9 \u1ea9m kh\u00f4ng qu\u00e1 70%, nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, n\u01a1i kh\u00f4 r\u00e1o, s\u1ea1ch s\u1ebd. \u0110\u1ec3 tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Plendil 5mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/mibeplen-5mg\/\">Mibeplen 5mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Felodipin 5mg, s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Hasan \u2013 Dermapharm, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00e0 d\u1ef1 ph\u00f2ng c\u00e1c c\u01a1n \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/felodipine-stella-5mg-retard\/\">Felodipine Stella 5mg Retard<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Felodipin 5mg, s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Stellapharm, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00e0 \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/plendil-plus\/\">Plendil Plus<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Felodipin v\u00e0 Metoprolol, s\u1ea3n xu\u1ea5t b\u1edfi ASTRAZENECA AB, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Plendil 5mg do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/HDSD-Plendil-5mg-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a><\/li>\n<li>Saltiel E, Ellrodt AG, Monk JP, Langley MS. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3069435\/\" rel=\"noopener\"> A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension<\/a>, truy c\u1eadp ng\u00e0y 17 th\u00e1ng 11 n\u0103m 2025<\/li>\n<li>Fuhr LM, Ma rok FZ, Mees M, Mahfoud F, Selzer D, Lehr T. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35890369\/\" rel=\"noopener\">A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug-Drug Interaction Modeling<\/a>, truy c\u1eadp ng\u00e0y 17 th\u00e1ng 11 n\u0103m 2025<\/li>\n<li>Edgar B, Reg\u00e5rdh CG, Lundborg P, Romare S, Nyberg G, R\u00f6nn O. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3593901\/\" rel=\"noopener\">Pharmacokinetic and pharmacodynamic studies of felodipine in healthy subjects after various single, oral and intravenous doses<\/a>, truy c\u1eadp ng\u00e0y 17 th\u00e1ng 11 n\u0103m 2025<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Plendil 5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi AstraZeneca AB, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-17835-14, \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p v\u00e0 \u0111au th\u1eaft ng\u1ef1c<\/p>\n","protected":false},"author":1,"featured_media":148614,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-148426","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/148426","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=148426"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/148614"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=148426"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=148426"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=148426"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}