{"id":147878,"date":"2025-11-11T23:06:29","date_gmt":"2025-11-11T16:06:29","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=147878"},"modified":"2025-11-11T23:08:28","modified_gmt":"2025-11-11T16:08:28","slug":"aslem-0-3mg-ml","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/aslem-0-3mg-ml\/","title":{"rendered":"Aslem 0.3mg\/ml"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Aslem 0.3mg\/ml \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi <\/b><b>C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m V\u0129nh Ph\u00fac <\/b><b>c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110272000 (S\u0110K c\u0169: VD-32032-19)<\/b><\/p>\n<h2>Aslem 0.3mg\/ml l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i<strong> \u1ed1ng ti\u00eam Aslem 0.3mg\/ml<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Glycyl funtumin hydroclorid &#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 0,3 mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Natri clorid, n\u01b0\u1edbc c\u1ea5t pha ti\u00eam v\u1eeba \u0111\u1ee7 1 ml.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Dung d\u1ecbch ti\u00eam<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110272000 (S\u0110K c\u0169: VD-32032-19)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 v\u1ec9 x 10 \u1ed1ng x 1ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Aslem 0.3mg\/ml<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Glycyl funtumin hydroclorid k\u00edch th\u00edch c\u1ea3 hai nh\u00e1nh c\u1ee7a h\u1ec7 mi\u1ec5n d\u1ecbch:<\/p>\n<ul>\n<li>Mi\u1ec5n d\u1ecbch d\u1ecbch th\u1ec3: Thu\u1ed1c l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng t\u1ea1o qu\u1ea7ng dung huy\u1ebft theo ph\u1ea3n \u1ee9ng Jerne Cunningham.<\/li>\n<li>Mi\u1ec5n d\u1ecbch t\u1ebf b\u00e0o: K\u00edch ho\u1ea1t ch\u1ee9c n\u0103ng th\u1ef1c b\u00e0o c\u1ee7a \u0111\u1ea1i th\u1ef1c b\u00e0o, th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh chuy\u1ec3n d\u1ea1ng lympho b\u00e0o v\u00e0 ph\u1ee5c h\u1ed3i kh\u1ea3 n\u0103ng t\u1ea1o Rosette E b\u1ecb \u1ee9c ch\u1ebf b\u1edfi theophylin.<br \/>\nNgo\u00e0i ra, thu\u1ed1c c\u00f2n gi\u00fap \u1ed5n \u0111\u1ecbnh m\u00e0ng h\u1ed3ng c\u1ea7u, lysosome v\u00e0 t\u0103ng s\u1ee9c \u0111\u1ec1 kh\u00e1ng v\u1edbi nhi\u1ec5m khu\u1ea9n in vivo, \u0111\u1eb7c bi\u1ec7t trong c\u00e1c m\u00f4 h\u00ecnh vi\u00eam ph\u00fac m\u1ea1c do tr\u1ef1c khu\u1ea9n m\u1ee7 xanh kh\u00e1ng thu\u1ed1c.<\/li>\n<\/ul>\n<p>\u1ede b\u1ec7nh nh\u00e2n ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng, ho\u1ea1t ch\u1ea5t l\u00e0m t\u0103ng ti\u1ebft cytokine type 1 (IL-2, IFN-\u03b3), \u0111\u1ed3ng th\u1eddi \u1ee9c ch\u1ebf cytokine type 2 (IL-4, IL-10), gi\u00fap c\u1ea3i thi\u1ec7n \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch ch\u1ed1ng kh\u1ed1i u.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>C\u00e1c nghi\u00ean c\u1ee9u tr\u00ean ng\u01b0\u1eddi t\u00ecnh nguy\u1ec7n kh\u1ecfe m\u1ea1nh \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n v\u1edbi li\u1ec1u \u0111\u01a1n 0,6 mg cho th\u1ea5y:<\/p>\n<ul>\n<li>Sau khi ti\u00eam b\u1eafp: N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng (Cmax) \u0111\u1ea1t kho\u1ea3ng 9,14 ng\/mL, xu\u1ea5t hi\u1ec7n sau 6,83 ph\u00fat (Tmax). Di\u1ec7n t\u00edch d\u01b0\u1edbi \u0111\u01b0\u1eddng cong (AUC) ghi nh\u1eadn kho\u1ea3ng 289,59 ng\u00b7ph\u00fat\/mL.<\/li>\n<li>Khi ti\u00eam t\u0129nh m\u1ea1ch: N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng t\u0103ng l\u00ean \u0111\u1ebfn 40,68 ng\/mL, \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 2 ph\u00fat, v\u1edbi AUC v\u00e0o kho\u1ea3ng 320,45 ng\u00b7ph\u00fat\/mL.<\/li>\n<\/ul>\n<p>T\u1eeb c\u00e1c d\u1eef li\u1ec7u n\u00e0y, sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i c\u1ee7a \u0111\u01b0\u1eddng ti\u00eam b\u1eafp \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh x\u1ea5p x\u1ec9 91,7%, cho th\u1ea5y thu\u1ed1c \u0111\u01b0\u1ee3c h\u1ea5p thu g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n khi ti\u00eam theo \u0111\u01b0\u1eddng n\u00e0y.<\/p>\n<h2>Thu\u1ed1c Aslem 0.3mg\/ml \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>H\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 sau ph\u1eabu thu\u1eadt, h\u00f3a tr\u1ecb ho\u1eb7c x\u1ea1 tr\u1ecb (ung th\u01b0 gan, d\u1ea1 d\u00e0y, \u0111\u1ea1i tr\u1ef1c tr\u00e0ng, ph\u1ed5i, v\u00fa).<\/p>\n<p>D\u00f9ng cho b\u1ec7nh nh\u00e2n ung th\u01b0 gan kh\u00f4ng c\u00f3 ch\u1ec9 \u0111\u1ecbnh ph\u1eabu thu\u1eadt nh\u1eb1m k\u00e9o d\u00e0i th\u1eddi gian s\u1ed1ng.<\/p>\n<p>Ph\u1ed1i h\u1ee3p v\u1edbi kh\u00e1ng sinh trong \u0111i\u1ec1u tr\u1ecb c\u00e1c nhi\u1ec5m tr\u00f9ng ngo\u1ea1i khoa nh\u01b0 vi\u00eam da nhi\u1ec5m khu\u1ea9n, nh\u1ecdt \u0111\u1ea7u \u0111inh.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Trong ung th\u01b0: 0,3 mg\/l\u1ea7n, ti\u00eam 3 l\u1ea7n\/tu\u1ea7n, d\u00f9ng ngay sau ph\u1eabu thu\u1eadt v\u00e0 trong c\u00e1c \u0111\u1ee3t h\u00f3a tr\u1ecb ho\u1eb7c x\u1ea1 tr\u1ecb. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb n\u00ean k\u00e9o d\u00e0i \u00edt nh\u1ea5t 2 n\u0103m \u0111\u1ec3 \u0111\u1ea1t hi\u1ec7u qu\u1ea3 t\u1ed1i \u01b0u.<\/p>\n<p>Trong nhi\u1ec5m tr\u00f9ng ngo\u1ea1i khoa: 1 \u2013 3 \u1ed1ng\/ng\u00e0y, d\u00f9ng c\u00f9ng kh\u00e1ng sinh v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1eb7c hi\u1ec7u. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb 2 \u2013 10 ng\u00e0y t\u00f9y m\u1ee9c \u0111\u1ed9 \u0111\u00e1p \u1ee9ng.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>Ti\u00eam b\u1eafp, ti\u00eam d\u01b0\u1edbi da ho\u1eb7c ti\u00eam t\u0129nh m\u1ea1ch theo ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129. Kh\u00f4ng \u0111\u01b0\u1ee3c t\u1ef1 \u00fd tr\u1ed9n thu\u1ed1c v\u1edbi c\u00e1c dung d\u1ecbch kh\u00e1c.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Aslem 0.3mg\/ml trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi Glycyl funtumin ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c c\u00f3 trong Aslem 0.3mg\/ml<\/p>\n<p>Ph\u1ee5 n\u1eef \u0111ang mang thai<\/p>\n<p>M\u1eb9 \u0111ang trong th\u1eddi gian cho con b\u00fa.<\/p>\n<figure id=\"attachment_147879\" aria-describedby=\"caption-attachment-147879\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-147879\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Aslem-0.3mgml.jpg\" alt=\"Aslem 0.3mg\/ml\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Aslem-0.3mgml.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Aslem-0.3mgml-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Aslem-0.3mgml-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Aslem-0.3mgml-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Aslem-0.3mgml-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-147879\" class=\"wp-caption-text\">Thu\u1ed1c Aslem 0.3mg\/ml c\u00f3 t\u00e1c d\u1ee5ng t\u0103ng c\u01b0\u1eddng mi\u1ec5n d\u1ecbch cho c\u01a1 th\u1ec3<\/figcaption><\/figure>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea9n tr\u1ecdng khi d\u00f9ng Aslem 0.3mg\/ml cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng<\/p>\n<p>V\u1edbi b\u1ec7nh nh\u00e2n d\u01b0\u1edbi 18 tu\u1ed5i, ng\u01b0\u1eddi suy gan ho\u1eb7c suy th\u1eadn, c\u1ea7n \u0111\u00e1nh gi\u00e1 k\u1ef9 l\u1ee3i \u00edch \u2013 nguy c\u01a1 tr\u01b0\u1edbc khi d\u00f9ng.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>M\u1ed9t s\u1ed1 ph\u1ea3n \u1ee9ng c\u00f3 th\u1ec3 g\u1eb7p: m\u1ea9n ng\u1ee9a, n\u1ed5i m\u1ec1 \u0111ay, bu\u1ed3n n\u00f4n, n\u00f4n ho\u1eb7c t\u00e1o b\u00f3n.<\/p>\n<p>Hi\u1ec7n ch\u01b0a ghi nh\u1eadn t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng n\u00e0o trong qu\u00e1 tr\u00ecnh l\u01b0u h\u00e0nh thu\u1ed1c.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Ch\u01b0a c\u00f3 b\u00e1o c\u00e1o v\u1ec1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c \u0111\u00e1ng k\u1ec3. Tuy nhi\u00ean, kh\u00f4ng n\u00ean pha tr\u1ed9n Aslem v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c do ch\u01b0a c\u00f3 d\u1eef li\u1ec7u v\u1ec1 t\u00ednh t\u01b0\u01a1ng k\u1ef5.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u an to\u00e0n khi d\u00f9ng<strong> thu\u1ed1c ti\u00eam Aslem 0.3mg\/ml<\/strong> \u1edf ph\u1ee5 n\u1eef mang thai ho\u1eb7c cho con b\u00fa. N\u00ean tr\u00e1nh s\u1eed d\u1ee5ng Aslem cho c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Ch\u01b0a c\u00f3 b\u1eb1ng ch\u1ee9ng cho th\u1ea5y thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh thi\u1ebft b\u1ecb c\u01a1 gi\u1edbi.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Th\u1eed nghi\u1ec7m \u0111\u1ed9c t\u00ednh c\u1ea5p cho th\u1ea5y thu\u1ed1c c\u00f3 \u0111\u1ed9 an to\u00e0n cao, li\u1ec1u LD\u2085\u2080 c\u1ee7a Glycyl funtumin l\u1edbn h\u01a1n 12.000 l\u1ea7n li\u1ec1u \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Ch\u01b0a ghi nh\u1eadn tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u trong th\u1ef1c t\u1ebf. N\u1ebfu x\u1ea3y ra, \u0111i\u1ec1u tr\u1ecb ch\u1ee7 y\u1ebfu l\u00e0 theo d\u00f5i, h\u1ed7 tr\u1ee3 v\u00e0 x\u1eed tr\u00ed tri\u1ec7u ch\u1ee9ng th\u00edch h\u1ee3p.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Aslem 0.3mg\/ml \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Aslem 0.3mg\/ml trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Aslem 0.3mg\/ml khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Coimbra JRM, Moreira PI, Santos AE, Salvador JAR (2023). Therapeutic potential of glutaminyl cyclases: Current status and emerging trends. Drug Discov Today. Truy c\u1eadp ng\u00e0y 11 th\u00e1ng 11 n\u0103m 2025 t\u1eeb:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37244566\/\" rel=\"noopener\"> https:\/\/pubmed.ncbi.nlm.nih.gov\/37244566\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Aslem 0.3mg\/ml l\u00e0 thu\u1ed1c ti\u00eam c\u00f3 t\u00e1c d\u1ee5ng t\u0103ng c\u01b0\u1eddng mi\u1ec5n d\u1ecbch kh\u00f4ng \u0111\u1eb7c hi\u1ec7u, gi\u00fap c\u1ea3i thi\u1ec7n s\u1ee9c \u0111\u1ec1 kh\u00e1ng c\u1ee7a c\u01a1 th\u1ec3 trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p ung th\u01b0 ho\u1eb7c nhi\u1ec5m khu\u1ea9n n\u1eb7ng<\/p>\n","protected":false},"author":1,"featured_media":147888,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-147878","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/147878","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=147878"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/147888"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=147878"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=147878"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=147878"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}