{"id":147186,"date":"2025-11-04T11:00:23","date_gmt":"2025-11-04T04:00:23","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=147186"},"modified":"2025-11-04T15:52:11","modified_gmt":"2025-11-04T08:52:11","slug":"thuoc-nho-mat-phile","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/thuoc-nho-mat-phile\/","title":{"rendered":"Thu\u1ed1c nh\u1ecf m\u1eaft Phile"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n Thu\u1ed1c nh\u1ecf m\u1eaft Phileo \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Samchundang Pharm Co., Ltd., c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18735-15 <\/strong><\/p>\n<h2>Thu\u1ed1c nh\u1ecf m\u1eaft Phileo l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i ml Thu\u1ed1c nh\u1ecf m\u1eaft <strong>Phileo <\/strong>c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Levofloxacin: 5mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Dung d\u1ecbch nh\u1ecf m\u1eaft<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-18735-15<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 5ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: H\u00e0n Qu\u1ed1c<\/p>\n<figure id=\"attachment_147187\" aria-describedby=\"caption-attachment-147187\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-147187\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Phileo-7.jpg\" alt=\"Thu\u1ed1c nh\u1ecf m\u1eaft Phileo \u0111i\u1ec1u tr\u1ecb vi\u00eam mi m\u1eaft, vi\u00eam b\u1edd mi, vi\u00eam tuy\u1ebfn l\u1ec7\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Phileo-7.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Phileo-7-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Phileo-7-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Phileo-7-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Phileo-7-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-147187\" class=\"wp-caption-text\">Thu\u1ed1c nh\u1ecf m\u1eaft Phileo \u0111i\u1ec1u tr\u1ecb vi\u00eam mi m\u1eaft, vi\u00eam b\u1edd mi, vi\u00eam tuy\u1ebfn l\u1ec7<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a Thu\u1ed1c nh\u1ecf m\u1eaft Phileo<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p><strong>Levofloxacin<\/strong> l\u00e0 \u0111\u1ed3ng ph\u00e2n L c\u1ee7a ofloxacin, thu\u1ed9c nh\u00f3m kh\u00e1ng sinh quinolon, c\u00f3 ho\u1ea1t t\u00ednh m\u1ea1nh g\u1ea5p \u0111\u00f4i ofloxacin. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c d\u1ef1a tr\u00ean \u1ee9c ch\u1ebf enzyme topoisomerase IV v\u00e0 DNA gyrase (\u0111\u1ec1u thu\u1ed9c nh\u00f3m topoisomerase II) \u2013 c\u00e1c enzyme c\u1ea7n thi\u1ebft cho qu\u00e1 tr\u00ecnh nh\u00e2n \u0111\u00f4i, s\u1eeda ch\u1eefa v\u00e0 t\u00e1i t\u1ed5 h\u1ee3p DNA c\u1ee7a vi khu\u1ea9n.<\/p>\n<p>Levofloxacin c\u00f3 ph\u1ed5 kh\u00e1ng khu\u1ea9n r\u1ed9ng, t\u00e1c \u0111\u1ed9ng tr\u00ean nhi\u1ec1u ch\u1ee7ng vi khu\u1ea9n Gram d\u01b0\u01a1ng v\u00e0 Gram \u00e2m. \u1ede n\u1ed3ng \u0111\u1ed9 di\u1ec7t khu\u1ea9n, thu\u1ed1c \u0111\u1ea1t hi\u1ec7u l\u1ef1c t\u01b0\u01a1ng \u0111\u01b0\u01a1ng ho\u1eb7c cao h\u01a1n n\u1ed3ng \u0111\u1ed9 \u1ee9c ch\u1ebf vi khu\u1ea9n, th\u1ec3 hi\u1ec7n hi\u1ec7u qu\u1ea3 t\u1ed1t trong nghi\u00ean c\u1ee9u in vitro v\u00e0 tr\u00ean l\u00e2m s\u00e0ng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Sau khi nh\u1ecf m\u1eaft, n\u1ed3ng \u0111\u1ed9 trung b\u00ecnh c\u1ee7a levofloxacin trong n\u01b0\u1edbc m\u1eaft dao \u0111\u1ed9ng t\u1eeb 34,9 \u0111\u1ebfn 221,2 \u00b5g\/ml trong v\u00f2ng 60 ph\u00fat. Sau 4 gi\u1edd, n\u1ed3ng \u0111\u1ed9 c\u00f2n kho\u1ea3ng 17,0 \u00b5g\/ml, v\u00e0 sau 6 gi\u1edd gi\u1ea3m c\u00f2n 6,6 \u00b5g\/ml.<\/p>\n<h2>Thu\u1ed1c nh\u1ecf m\u1eaft Phileo \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c nh\u1ecf m\u1eaft Phileo \u0111\u01b0\u1ee3c d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb vi\u00eam mi m\u1eaft, vi\u00eam b\u1edd mi, vi\u00eam tuy\u1ebfn l\u1ec7, vi\u00eam k\u1ebft m\u1ea1c, vi\u00eam gi\u00e1c m\u1ea1c, lo\u00e9t gi\u00e1c m\u1ea1c v\u00e0 s\u00e1t khu\u1ea9n trong qu\u00e1 tr\u00ecnh ph\u1eabu thu\u1eadt m\u1eaft.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Ng\u00e0y 1-2: nh\u1ecf 1-2 gi\u1ecdt Thu\u1ed1c nh\u1ecf m\u1eaft Phileo v\u00e0o m\u1eaft b\u1ecb nhi\u1ec5m, m\u1ed7i 2 gi\u1edd\/l\u1ea7n, 8 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Ng\u00e0y 3-7: nh\u1ecf 1-2 gi\u1ecdt Thu\u1ed1c nh\u1ecf m\u1eaft Phileo, m\u1ed7i 4 gi\u1edd\/l\u1ea7n, 4 l\u1ea7n\/ng\u00e0y.<\/p>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c nh\u1ecf m\u1eaft Phileo ch\u1ec9 d\u00f9ng t\u1ea1i ch\u1ed7.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng Thu\u1ed1c nh\u1ecf m\u1eaft Phileo trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng d\u00f9ng cho ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi levofloxacin, c\u00e1c kh\u00e1ng sinh nh\u00f3m quinolon ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>D\u00f9ng Thu\u1ed1c nh\u1ecf m\u1eaft Phileo k\u00e9o d\u00e0i c\u00f3 th\u1ec3 g\u00e2y ph\u00e1t tri\u1ec3n vi khu\u1ea9n kh\u00f4ng nh\u1ea1y c\u1ea3m, k\u1ec3 c\u1ea3 n\u1ea5m, n\u1ebfu x\u1ea3y ra b\u1ed9i nhi\u1ec5m, c\u1ea7n ng\u01b0ng thu\u1ed1c v\u00e0 \u0111\u1ed5i \u0111i\u1ec1u tr\u1ecb kh\u00e1c.<\/p>\n<p>Tr\u00e1nh \u0111\u1ec3 \u0111\u1ea7u l\u1ecd ti\u1ebfp x\u00fac v\u1edbi m\u1eaft ho\u1eb7c b\u1ec1 m\u1eb7t kh\u00e1c \u0111\u1ec3 kh\u00f4ng l\u00e0m nhi\u1ec5m b\u1ea9n dung d\u1ecbch.<\/p>\n<p>Ng\u01b0\u1eddi \u0111eo k\u00ednh \u00e1p tr\u00f2ng ph\u1ea3i th\u00e1o ra tr\u01b0\u1edbc khi nh\u1ecf Thu\u1ed1c nh\u1ecf m\u1eaft Phileo, ch\u1ec9 \u0111eo l\u1ea1i sau \u00edt nh\u1ea5t 30 ph\u00fat.<\/p>\n<p>Thu\u1ed1c nh\u1ecf m\u1eaft Phileo ch\u1ec9 d\u00f9ng nh\u1ecf t\u1ea1i m\u1eaft, kh\u00f4ng ti\u00eam.<\/p>\n<p>Kh\u00f4ng d\u00f9ng Thu\u1ed1c nh\u1ecf m\u1eaft Phileo qu\u00e1 h\u1ea1n v\u00e0 ch\u1ec9 n\u00ean s\u1eed d\u1ee5ng trong v\u00f2ng 1 th\u00e1ng sau khi m\u1edf n\u1eafp.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p (1-3%): gi\u1ea3m th\u1ecb l\u1ef1c, \u0111au ho\u1eb7c r\u00e1t m\u1eaft, c\u1ea3m gi\u00e1c c\u00f3 d\u1ecb v\u1eadt, s\u1ed1t nh\u1eb9, vi\u00eam h\u1ecdng, s\u1ee3 \u00e1nh s\u00e1ng.<\/p>\n<p>\u00cdt g\u1eb7p (&lt;1%): d\u1ecb \u1ee9ng, s\u01b0ng mi, kh\u00f4 ho\u1eb7c ng\u1ee9a m\u1eaft.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Ch\u01b0a c\u00f3 b\u00e1o c\u00e1o v\u1ec1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c khi d\u00f9ng t\u1ea1i ch\u1ed7 \u1edf m\u1eaft, tuy nhi\u00ean, v\u1edbi d\u1ea1ng u\u1ed1ng c\u1ee7a m\u1ed9t s\u1ed1 quinolon, c\u00f3 th\u1ec3 g\u1eb7p:<\/p>\n<ul>\n<li>T\u0103ng n\u1ed3ng \u0111\u1ed9 theophyllin trong huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<li>\u1ee8c ch\u1ebf chuy\u1ec3n h\u00f3a caffeine.<\/li>\n<li>T\u0103ng t\u00e1c d\u1ee5ng ch\u1ed1ng \u0111\u00f4ng c\u1ee7a warfarin v\u00e0 c\u00e1c d\u1eabn xu\u1ea5t.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Thai k\u1ef3: ch\u01b0a \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n; ch\u1ec9 d\u00f9ng Thu\u1ed1c nh\u1ecf m\u1eaft Phileo khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 cho thai.<\/p>\n<p>Cho con b\u00fa: levofloxacin c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9, n\u00ean c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Thu\u1ed1c nh\u1ecf m\u1eaft Phileo.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Kh\u00f4ng n\u00ean d\u00f9ng Thu\u1ed1c nh\u1ecf m\u1eaft Phileo khi \u0111ang l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, do c\u00f3 th\u1ec3 g\u00e2y m\u1edd m\u1eaft tho\u00e1ng qua sau khi nh\u1ecf.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u khi nh\u1ecf m\u1eaft hi\u1ebfm g\u1eb7p, tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng t\u01b0\u01a1ng t\u1ef1 t\u00e1c d\u1ee5ng ph\u1ee5 nh\u1eb9. Khi x\u1ea3y ra, c\u1ea7n r\u1eeda m\u1eaft b\u1eb1ng n\u01b0\u1edbc s\u1ea1ch v\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng n\u1ebfu c\u1ea7n.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Thu\u1ed1c nh\u1ecf m\u1eaft Phileo \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<br \/>\nKh\u00f4ng \u0111\u1ec3 Thu\u1ed1c nh\u1ecf m\u1eaft Phileo trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Thu\u1ed1c nh\u1ecf m\u1eaft Phileo khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Thu\u1ed1c nh\u1ecf m\u1eaft Phileo nh\u01b0:<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/cravit-1-5-santen\/\">Cravit 1.5% Santen<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Levofloxacin, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Santen Pharmaceutical Co., Ltd, ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam b\u1edd mi, vi\u00eam k\u1ebft m\u1ea1c, vi\u00eam gi\u00e1c m\u1ea1c<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/eyexacin-25mg-5ml\/\">Eyexacin 25mg\/5ml<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Levofloxacin, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c \u2013 Trang thi\u1ebft b\u1ecb y t\u1ebf B\u00ecnh \u0110\u1ecbnh (Bidiphar), ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam k\u1ebft m\u1ea1c do c\u00e1c vi khu\u1ea9n nh\u1ea1y c\u1ea3m v\u1edbi thu\u1ed1c<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>G Li, L Xu v\u00e0 c\u00e1c c\u1ed9ng s\u1ef1 (2020), Eye drops and eye gels of levofloxacin: Comparison of ocular absorption characterizations and therapeutic effects in the treatment of bacterial keratitis in rabbits. Taylor &amp; Francis. Truy c\u1eadp ng\u00e0y 4 th\u00e1ng 11 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/03639045.2020.1750626\" rel=\"noopener\">https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/03639045.2020.1750626<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c nh\u1ecf m\u1eaft Phileo \u0111\u01b0\u1ee3c d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb vi\u00eam mi m\u1eaft, vi\u00eam b\u1edd mi, vi\u00eam tuy\u1ebfn l\u1ec7, vi\u00eam k\u1ebft m\u1ea1c, vi\u00eam gi\u00e1c m\u1ea1c, lo\u00e9t gi\u00e1c m\u1ea1c v\u00e0 s\u00e1t khu\u1ea9n trong qu\u00e1 tr\u00ecnh ph\u1eabu thu\u1eadt m\u1eaft.<\/p>\n","protected":false},"author":1,"featured_media":147188,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-147186","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/147186","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=147186"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/147188"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=147186"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=147186"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=147186"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}