{"id":146793,"date":"2025-10-31T14:31:14","date_gmt":"2025-10-31T07:31:14","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=146793"},"modified":"2025-10-31T14:33:04","modified_gmt":"2025-10-31T07:33:04","slug":"givet-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/givet-5\/","title":{"rendered":"Givet-5"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Givet-5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi <\/b><b>C\u00f4ng ty C\u1ed5 Ph\u1ea7n D\u01b0\u1ee3c Ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa <\/b><b>c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-14582-11<\/b><\/p>\n<h2>Givet-5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Givet-5<\/strong> c\u00f3 ch\u1ee9a Montelukast h\u00e0m l\u01b0\u1ee3ng 5mg v\u00e0 t\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-14582-11<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 4 v\u1ec9 x 7 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Givet-5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Montelukast l\u00e0 m\u1ed9t ch\u1ea5t \u0111\u1ed1i kh\u00e1ng \u0111\u1eb7c hi\u1ec7u v\u00e0 c\u00f3 \u00e1i l\u1ef1c cao v\u1edbi th\u1ee5 th\u1ec3 Cysteinyl Leukotrien lo\u1ea1i 1 (CysLT\u2081) \u2013 nh\u1eefng th\u1ee5 th\u1ec3 n\u00e0y c\u00f3 m\u1eb7t \u1edf c\u01a1 tr\u01a1n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, t\u1ebf b\u00e0o vi\u00eam v\u00e0 c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch nh\u01b0 b\u1ea1ch c\u1ea7u \u00e1i toan. Khi \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t b\u1edfi c\u00e1c leukotrien (LTC\u2084, LTD\u2084, LTE\u2084), c\u00e1c th\u1ee5 th\u1ec3 n\u00e0y g\u00e2y ra hi\u1ec7n t\u01b0\u1ee3ng co th\u1eaft ph\u1ebf qu\u1ea3n, t\u0103ng ti\u1ebft nh\u1ea7y, ph\u00f9 n\u1ec1 ni\u00eam m\u1ea1c v\u00e0 thu h\u00fat t\u1ebf b\u00e0o vi\u00eam.<\/p>\n<p>Montelukast ng\u0103n c\u1ea3n c\u00e1c leukotrien g\u1eafn v\u00e0o th\u1ee5 th\u1ec3 CysLT\u2081, nh\u1edd \u0111\u00f3 gi\u1ea3m t\u00ecnh tr\u1ea1ng vi\u00eam, ng\u0103n co th\u1eaft ph\u1ebf qu\u1ea3n v\u00e0 gi\u1ea3m t\u1eafc ngh\u1ebdn \u0111\u01b0\u1eddng th\u1edf. Thu\u1ed1c kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng ch\u1ee7 v\u1eadn, kh\u00f4ng t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn c\u00e1c th\u1ee5 th\u1ec3 kh\u00e1c nh\u01b0 adrenergic, cholinergic hay prostanoid.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Montelukast \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a ngay sau khi u\u1ed1ng. V\u1edbi d\u1ea1ng vi\u00ean nhai 5 mg, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 2 gi\u1edd. T\u1ef7 l\u1ec7 h\u1ea5p thu c\u1ee7a thu\u1ed1c \u0111\u1ea1t x\u1ea5p x\u1ec9 37%, kh\u00f4ng ch\u1ecbu \u1ea3nh h\u01b0\u1edfng r\u00f5 r\u1ec7t b\u1edfi th\u1ee9c \u0103n.<\/p>\n<p>Ph\u00e2n b\u1ed1: Montelukast li\u00ean k\u1ebft g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, v\u1edbi t\u1ef7 l\u1ec7 g\u1eafn k\u1ebft v\u01b0\u1ee3t qu\u00e1 99% v\u00e0 c\u00f3 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 trong kho\u1ea3ng 8\u201311 l\u00edt. Ho\u1ea1t ch\u1ea5t n\u00e0y ch\u1ec9 \u0111i qua h\u00e0ng r\u00e0o m\u00e1u n\u00e3o v\u1edbi l\u01b0\u1ee3ng r\u1ea5t nh\u1ecf.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Montelukast \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a m\u1ea1nh \u1edf gan th\u00f4ng qua h\u1ec7 enzyme cytochrome P450 (ch\u1ee7 y\u1ebfu l\u00e0 CYP3A4, CYP2C8, CYP2C9). \u1ede li\u1ec1u \u0111i\u1ec1u tr\u1ecb, ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a Montelukast c\u00f3 l\u01b0\u1ee3ng t\u00edch l\u0169y trong c\u01a1 th\u1ec3 kh\u00f4ng \u0111\u00e1ng k\u1ec3.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Kho\u1ea3ng 86% l\u01b0\u1ee3ng thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i qua ph\u00e2n trong v\u00f2ng 5 ng\u00e0y, ph\u1ea7n c\u00f2n l\u1ea1i r\u1ea5t \u00edt qua n\u01b0\u1edbc ti\u1ec3u. Thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb kh\u1ecfi c\u01a1 th\u1ec3 v\u1edbi th\u1eddi gian b\u00e1n h\u1ee7y trung b\u00ecnh kho\u1ea3ng 2,7 \u0111\u1ebfn 5,5 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Givet-5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>D\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 6 tu\u1ed5i tr\u1edf l\u00ean.<\/p>\n<p>Ph\u00f2ng ng\u1eeba co th\u1eaft ph\u1ebf qu\u1ea3n do g\u1eafng s\u1ee9c.<\/p>\n<p>Gi\u1ea3m tri\u1ec7u ch\u1ee9ng c\u1ee7a vi\u00eam m\u0169i d\u1ecb \u1ee9ng theo m\u00f9a ho\u1eb7c quanh n\u0103m.<\/p>\n<p>H\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n nh\u1ea1y c\u1ea3m v\u1edbi aspirin.<\/p>\n<figure id=\"attachment_146815\" aria-describedby=\"caption-attachment-146815\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-146815\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Givet-5-1.jpg\" alt=\"Givet-5\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Givet-5-1.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Givet-5-1-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Givet-5-1-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Givet-5-1-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Givet-5-1-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-146815\" class=\"wp-caption-text\">Thu\u1ed1c Givet-5 c\u00f3 t\u00e1c d\u1ee5ng ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Ng\u01b0\u1eddi l\u1edbn v\u00e0 thanh thi\u1ebfu ni\u00ean t\u1eeb 15 tu\u1ed5i tr\u1edf l\u00ean: U\u1ed1ng 2 vi\u00ean Givet lo\u1ea1i 5mg m\u1ed7i ng\u00e0y<\/p>\n<p>Tr\u1ebb em 6\u201314 tu\u1ed5i: ng\u00e0y d\u00f9ng 1 vi\u00ean<\/p>\n<p>Tr\u1ebb em 6 th\u00e1ng \u2013 5 tu\u1ed5i: d\u00f9ng d\u1ea1ng c\u1ed1m u\u1ed1ng 4 mg\/ng\u00e0y.<\/p>\n<p>U\u1ed1ng m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y, th\u01b0\u1eddng v\u00e0o bu\u1ed5i t\u1ed1i n\u1ebfu \u0111i\u1ec1u tr\u1ecb hen, ho\u1eb7c t\u00f9y th\u1eddi \u0111i\u1ec3m khi \u0111i\u1ec1u tr\u1ecb vi\u00eam m\u0169i d\u1ecb \u1ee9ng.<\/p>\n<p>Duy tr\u00ec thu\u1ed1c ngay c\u1ea3 khi tri\u1ec7u ch\u1ee9ng \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>D\u00f9ng qua \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 nhai ho\u1eb7c nu\u1ed1t nguy\u00ean vi\u00ean Givet k\u00e8m n\u01b0\u1edbc; d\u00f9ng c\u00f9ng hay kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n \u0111\u1ec1u kh\u00f4ng l\u00e0m thay \u0111\u1ed5i h\u1ea5p thu thu\u1ed1c.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Givet-5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi Montelukast hay t\u00e1 d\u01b0\u1ee3c c\u00f3 trong <strong>vi\u00ean n\u00e9n Givet-5<\/strong><\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng \u1edf b\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n di truy\u1ec1n hi\u1ebfm g\u1eb7p nh\u01b0 kh\u00f4ng dung n\u1ea1p galactose, thi\u1ebfu men Lapp lactase ho\u1eb7c r\u1ed1i lo\u1ea1n h\u1ea5p thu glucose-galactose.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Givet-5 kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 x\u1eed tr\u00ed c\u01a1n hen c\u1ea5p. Trong t\u00ecnh hu\u1ed1ng n\u00e0y, ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n s\u1eed d\u1ee5ng thu\u1ed1c gi\u00e3n ph\u1ebf qu\u1ea3n c\u00f3 t\u00e1c d\u1ee5ng nhanh \u0111\u1ec3 c\u1eaft c\u01a1n k\u1ecbp th\u1eddi.<\/p>\n<p>KKh\u00f4ng n\u00ean d\u1eebng ho\u1eb7c thay \u0111\u1ed5i li\u1ec1u thu\u1ed1c corticosteroid \u0111\u1ed9t ng\u1ed9t m\u00e0 kh\u00f4ng c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129. Vi\u1ec7c gi\u1ea3m li\u1ec1u steroid c\u1ea7n ti\u1ebfn h\u00e0nh t\u1eeb t\u1eeb v\u00e0 c\u00f3 gi\u00e1m s\u00e1t y khoa.<\/p>\n<p>M\u1ed9t s\u1ed1 ng\u01b0\u1eddi c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n t\u0103ng b\u1ea1ch c\u1ea7u \u00e1i toan, ph\u00e1t ban, kh\u00f3 th\u1edf ho\u1eb7c bi\u1ebfn ch\u1ee9ng th\u1ea7n kinh \u2013 tim m\u1ea1ch, \u0111\u00f4i khi bi\u1ec3u hi\u1ec7n h\u1ed9i ch\u1ee9ng Churg\u2013Strauss khi gi\u1ea3m steroid, n\u00ean c\u1ea7n theo d\u00f5i k\u1ef9.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ecb hen do aspirin v\u1eabn c\u1ea7n tr\u00e1nh ho\u00e0n to\u00e0n aspirin v\u00e0 thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID).<\/p>\n<p>Thu\u1ed1c c\u00f3 ch\u1ee9a polysorbat 80, m\u00e0u t\u1ed5ng h\u1ee3p (quinolin yellow, sunset yellow) v\u00e0 d\u1ea7u th\u1ea7u d\u1ea7u, c\u00f3 th\u1ec3 g\u00e2y ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng ho\u1eb7c kh\u00f3 ch\u1ecbu \u0111\u01b0\u1eddng ti\u00eau h\u00f3a \u1edf m\u1ed9t s\u1ed1 ng\u01b0\u1eddi.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>C\u00e1c ph\u1ea3n \u1ee9ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a Givet-5 nh\u00ecn chung nh\u1eb9 v\u00e0 tho\u00e1ng qua, \u0111\u01b0\u1ee3c ghi nh\u1eadn \u1edf t\u1ea7n su\u1ea5t kh\u00e1c nhau:<\/p>\n<p>R\u1ea5t th\u01b0\u1eddng g\u1eb7p: Nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean.<\/p>\n<p>Th\u01b0\u1eddng g\u1eb7p: \u0110au b\u1ee5ng, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, ph\u00e1t ban, s\u1ed1t, t\u0103ng nh\u1eb9 men gan.<\/p>\n<p>\u00cdt g\u1eb7p: Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn, r\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7 (\u00e1c m\u1ed9ng, m\u1ed9ng du), lo l\u1eafng, d\u1ec5 k\u00edch \u0111\u1ed9ng, tr\u1ea7m c\u1ea3m, run, ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7, ch\u1ea3y m\u00e1u cam, ng\u1ee9a, n\u1ed5i m\u1ec1 \u0111ay, \u0111au c\u01a1 ho\u1eb7c kh\u1edbp, m\u1ec7t m\u1ecfi, ph\u00f9.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: R\u1ed1i lo\u1ea1n ch\u00fa \u00fd, gi\u1ea3m tr\u00ed nh\u1edb, \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, ph\u00f9 m\u1ea1ch, khuynh h\u01b0\u1edbng ch\u1ea3y m\u00e1u t\u0103ng.<\/p>\n<p>R\u1ea5t hi\u1ebfm: \u1ea2o gi\u00e1c, m\u1ea5t \u0111\u1ecbnh h\u01b0\u1edbng, \u00fd ngh\u0129 t\u1ef1 s\u00e1t, vi\u00eam gan, h\u1ed3ng ban \u0111a d\u1ea1ng, h\u1ed3ng ban n\u00fat, th\u00e2m nhi\u1ec5m b\u1ea1ch c\u1ea7u \u00e1i toan t\u1ea1i gan, ho\u1eb7c h\u1ed9i ch\u1ee9ng Churg\u2013Strauss \u1edf ph\u1ed5i.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Givet-5 c\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb hen kh\u00e1c nh\u01b0 theophylin, prednison, prednisolon, digoxin, warfarin ho\u1eb7c thu\u1ed1c tr\u00e1nh thai m\u00e0 kh\u00f4ng g\u00e2y thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 v\u1ec1 d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc.<\/p>\n<p>Phenobarbital, phenytoin, rifampicin c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 montelukast trong huy\u1ebft t\u01b0\u01a1ng do c\u1ea3m \u1ee9ng enzym gan (CYP3A4, CYP2C8, CYP2C9).<\/p>\n<p>Gemfibrozil, thu\u1ed1c \u1ee9c ch\u1ebf CYP2C8 v\u00e0 CYP2C9, c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 montelukast trong m\u00e1u l\u00ean kho\u1ea3ng 4 l\u1ea7n \u2014 n\u00ean theo d\u00f5i t\u00e1c d\u1ee5ng ph\u1ee5 khi d\u00f9ng chung.<\/p>\n<p>Itraconazol v\u00e0 trimethoprim h\u1ea7u nh\u01b0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn chuy\u1ec3n h\u00f3a c\u1ee7a montelukast.<\/p>\n<p>Khi ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng vi\u00eam corticosteroid d\u1ea1ng h\u00edt, kh\u00f4ng \u0111\u01b0\u1ee3c ng\u1eebng corticosteroid \u0111\u1ed9t ng\u1ed9t<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef mang thai: Nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt ch\u01b0a ghi nh\u1eadn t\u00e1c d\u1ee5ng g\u00e2y h\u1ea1i c\u1ee7a montelukast \u0111\u1ebfn thai ho\u1eb7c s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a b\u00e0o thai, tuy nhi\u00ean d\u1eef li\u1ec7u tr\u00ean ng\u01b0\u1eddi c\u00f2n h\u1ea1n ch\u1ebf. V\u00ec v\u1eady, ch\u1ec9 n\u00ean d\u00f9ng Givet-5 cho ph\u1ee5 n\u1eef mang thai khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 ti\u1ec1m t\u00e0ng cho thai nhi.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa:<br \/>\nTheo nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt, montelukast c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9. Ch\u01b0a r\u00f5 \u1edf ng\u01b0\u1eddi c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng n\u00e0y hay kh\u00f4ng, do \u0111\u00f3 ch\u1ec9 n\u00ean s\u1eed d\u1ee5ng khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 \u0111\u01b0\u1ee3c b\u00e1c s\u0129 ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Givet-5 h\u1ea7u nh\u01b0 kh\u00f4ng t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn s\u1ef1 t\u1ec9nh t\u00e1o, nh\u01b0ng \u0111\u00f4i khi c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7 ho\u1eb7c ch\u00f3ng m\u1eb7t nh\u1eb9. Ng\u01b0\u1eddi d\u00f9ng n\u00ean c\u1ea9n tr\u1ecdng khi l\u00e1i xe ho\u1eb7c \u0111i\u1ec1u khi\u1ec3n m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>D\u00f9ng li\u1ec1u cao t\u1edbi 200\u2013900 mg\/ng\u00e0y trong th\u1eddi gian ng\u1eafn ch\u01b0a ghi nh\u1eadn ph\u1ea3n \u1ee9ng nghi\u00eam tr\u1ecdng.<\/p>\n<p>Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 bao g\u1ed3m \u0111au b\u1ee5ng, n\u00f4n, bu\u1ed3n ng\u1ee7, kh\u00e1t n\u01b0\u1edbc ho\u1eb7c t\u0103ng \u0111\u1ed9ng nh\u1eb9.<\/p>\n<p>Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho montelukast; vi\u1ec7c \u0111i\u1ec1u tr\u1ecb ch\u1ee7 y\u1ebfu l\u00e0 theo d\u00f5i v\u00e0 x\u1eed tr\u00ed tri\u1ec7u ch\u1ee9ng.<\/p>\n<p>Qu\u00e1 tr\u00ecnh l\u1ecdc m\u00e1u hay th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3 trong vi\u1ec7c lo\u1ea1i tr\u1eeb montelukast kh\u1ecfi c\u01a1 th\u1ec3.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Givet-5 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Givet-5 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Givet-5 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Givet-5 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/opesinkast-5\/\">Opesinkast 5<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Montelukast (d\u01b0\u1edbi d\u1ea1ng montelukast sodium) 5mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m OPV, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/usalukast-5\/\">Usalukast 5<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Montelukast (d\u01b0\u1edbi d\u1ea1ng montelukast sodium) 5mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Ampharco U.S.A, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Mayoral K, Lizano-Barrantes C, Zamora V, Pont A, Miret C, Barrufet C, Caballero-Rabasco MA, Praena-Crespo M, Bercedo A, Valdesoiro-Navarrete L, Guerra MT, Pardo Y, Mart\u00ednez Zapata MJ, Garin O, Ferrer M; ARCA Group (2023). Montelukast in paediatric asthma and allergic rhinitis: a systematic review and meta-analysis. Eur Respir Rev. Truy c\u1eadp ng\u00e0y 31 th\u00e1ng 10 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37852659\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37852659\/<br \/>\n<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Givet-5 ch\u1ee9a Montelukast, gi\u00fap ng\u0103n ch\u1eb7n t\u00e1c \u0111\u1ed9ng c\u1ee7a leukotrien g\u00e2y co th\u1eaft v\u00e0 vi\u00eam \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, t\u1eeb \u0111\u00f3 ki\u1ec3m so\u00e1t hen ph\u1ebf qu\u1ea3n v\u00e0 gi\u1ea3m tri\u1ec7u ch\u1ee9ng vi\u00eam m\u0169i d\u1ecb \u1ee9ng<\/p>\n","protected":false},"author":1,"featured_media":146807,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-146793","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/146793","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=146793"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/146807"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=146793"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=146793"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=146793"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}