{"id":146558,"date":"2025-11-01T10:42:26","date_gmt":"2025-11-01T03:42:26","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=146558"},"modified":"2025-11-01T10:44:01","modified_gmt":"2025-11-01T03:44:01","slug":"komboglyze-xr-5mg-500mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/komboglyze-xr-5mg-500mg\/","title":{"rendered":"Komboglyze XR 5mg\/500mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/komboglyze-xr-5mg-500mg\/\">Komboglyze XR 5mg\/500mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi AstraZeneca Pharmaceuticals LP, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18679-15<\/strong><\/p>\n<h2>Komboglyze XR 5mg\/500mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Komboglyze XR 5mg\/500mg<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Saxagliptin 5 mg, Metformin hydroclorid 500 mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-18679-15<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 4 v\u1ec9 x 7 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: USA<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Komboglyze XR 5mg\/500mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Saxagliptin \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng h\u1ed7 tr\u1ee3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng tuyp 2, ho\u1ea1t \u0111\u1ed9ng d\u1ef1a tr\u00ean c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf dipeptidyl peptidase-4 (DPP-4) nh\u1edd t\u00e1c \u0111\u1ed9ng l\u00ean ho\u1ea1t \u0111\u1ed9ng c\u1ee7a incretin. Incretin c\u00f3 kh\u1ea3 n\u0103ng t\u0103ng c\u01b0\u1eddng l\u01b0\u1ee3ng \u0111\u01b0\u1eddng s\u1eed d\u1ee5ng trong c\u01a1 th\u1ec3, t\u1eeb \u0111\u00f3 gi\u1ea3m n\u1ed3ng \u0111\u1ed9 \u0111\u01b0\u1eddng huy\u1ebft, t\u0103ng c\u01b0\u1eddng qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t insulin \u1edf tuy\u1ebfn t\u1ee5y v\u00e0 h\u1ea1n ch\u1ebf qu\u00e1 tr\u00ecnh t\u00e2n t\u1ea1o \u0111\u01b0\u1eddng \u1edf gan.<\/p>\n<p>Metformin gi\u00fap gi\u1ea3m qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p glucose \u1edf gan, h\u1ea1n ch\u1ebf s\u1ef1 h\u1ea5p thu glucose \u1edf ru\u1ed9t v\u00e0 c\u1ea3i thi\u1ec7n t\u00ednh n\u1ea1y c\u1ea3m insulin, t\u0103ng c\u01b0\u1eddng s\u1eed d\u1ee5ng glucose ngo\u1ea1i v\u1ecb. Metformin h\u1ed7 tr\u1ee3 c\u1ea3i thi\u1ec7n s\u1ef1 dung n\u1ea1p \u0111\u01b0\u1eddng \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2 \u1edf c\u1ea3 \u0111i\u1ec1u ki\u1ec7n c\u01a1 b\u1ea3n v\u00e0 ngay sau b\u1eefa \u0103n.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Saxagliptin s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng c\u00f3 sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 67%, n\u1ed3ng \u0111\u1ed9 thu\u1ed1c \u0111\u1ea1t \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau kho\u1ea3ng 2 gi\u1edd (Saxagliptin) v\u00e0 4 gi\u1edd (ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh c\u1ee7a Saxagliptin- 5-hydroxy saxagliptin) sau khi d\u00f9ng li\u1ec1u 5mg. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a thu\u1ed1c kho\u1ea3ng 151L, t\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kh\u00f4ng \u0111\u00e1ng k\u1ec3, d\u01b0\u1edbi 10%. Saxagliptin chuy\u1ec3n h\u00f3a ch\u00ednh t\u1ea1i gan, t\u1ea1o th\u00e0nh 5-hydroxy saxagliptin c\u00f3 ho\u1ea1t t\u00ednh b\u1eb1ng \u00bd v\u1edbi thu\u1ed1c g\u1ed1c. Thu\u1ed1c \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua \u0111\u01b0\u1eddng th\u1eadn v\u00e0 \u0111\u01b0\u1eddng gan.<\/p>\n<p>Metformin sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 50-60%. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 bi\u1ec3u ki\u1ebfn kho\u1ea3ng 654 \u00b1 358L, t\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kh\u00f4ng \u0111\u00e1ng k\u1ec3. Metformin kh\u00f4ng chuy\u1ec3n h\u00f3a t\u1ea1i gan v\u00e0 \u0111\u00e0o th\u1ea3o d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i qua n\u01b0\u1edbc ti\u1ec3u. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a thu\u1ed1c trong huy\u1ebft t\u01b0\u01a1ng sau kho\u1ea3ng 6,2 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Komboglyze XR 5mg\/500mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c <strong>Komboglyze XR 5mg\/500mg<\/strong> \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng typ 2 \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 thanh thi\u1ebfu ni\u00ean tr\u00ean 18 tu\u1ed5i.<\/p>\n<figure id=\"attachment_146930\" aria-describedby=\"caption-attachment-146930\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-146930\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Komboglyze-XR-5mg500mg.jpg\" alt=\"Thu\u1ed1c Komboglyze XR 5mg\/500mg \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Komboglyze-XR-5mg500mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Komboglyze-XR-5mg500mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Komboglyze-XR-5mg500mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Komboglyze-XR-5mg500mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/Komboglyze-XR-5mg500mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-146930\" class=\"wp-caption-text\">Thu\u1ed1c Komboglyze XR 5mg\/500mg \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Komboglyze XR 5mg\/500mg<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<ul>\n<li>Li\u1ec1u khuy\u1ebfn c\u00e1o: s\u1eed d\u1ee5ng 1 vi\u00ean Komboglyze XR 5mg\/500mg \/l\u1ea7n\/ng\u00e0y<\/li>\n<li>T\u00f9y thu\u1ed9c v\u00e0o kh\u1ea3 n\u0103ng \u0111\u00e1p \u1ee9ng c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean d\u1ea1 d\u00e0y, ru\u1ed9t, \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u ph\u00f9 h\u1ee3p<\/li>\n<\/ul>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c Komboglyze XR 5mg\/500mg d\u1ea1ng vi\u00ean n\u00e9n bao phim, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Komboglyze XR 5mg\/500mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Komboglyze XR 5mg\/500mg trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinine d\u01b0\u1edbi 30 ml\/ph\u00fat<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi metformin<\/li>\n<li>\u0110\u1ed1i t\u01b0\u1ee3ng nhi\u1ec5m toan chuy\u1ec3n h\u00f3a c\u1ea5p t\u00ednh v\u00e0 m\u1ea1n t\u00ednh<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn nghi\u00eam tr\u1ecdng khi s\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb Komboglyze XR h\u00e0m l\u01b0\u1ee3ng kh\u00e1c<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Komboglyze XR 5mg\/500mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>T\u00ecnh tr\u1ea1ng nhi\u1ec5m acid lactic \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng thu\u1ed1c, xu\u1ea5t hi\u1ec7n tri\u1ec7u ch\u1ee9ng gi\u1ea3m th\u00e2n nhi\u1ec7t, lo\u1ea1n nh\u1ecbp tim, t\u1ee5t huy\u1ebft \u00e1p, c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong. Nguy c\u01a1 t\u0103ng cao \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn, ng\u01b0\u1eddi cao tu\u1ed5i, b\u1ec7nh nh\u00e2n suy tim sung huy\u1ebft c\u1ea5p t\u00ednh, nghi\u1ec7n r\u01b0\u1ee3u, suy gan. B\u1ec7nh nh\u00e2n nghi ng\u1edd nhi\u1ec5m acid lactic c\u1ea7n ng\u01b0ng s\u1eed d\u1ee5ng thu\u1ed1c ngay v\u00e0 b\u00e1o c\u00e1o v\u1edbi b\u00e1c s\u0129.<\/li>\n<li>Theo d\u00f5i \u0111\u1ecbnh k\u1ef3 ch\u1ee9c n\u0103ng th\u1eadn trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n c\u00f3 eGFR 30-45 ml\/ph\u00fat\/1,73m2; ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 eGFR &lt; 30 ml\/ph\u00fat\/1,73m2. \u0110\u00e1nh gi\u00e1 l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 khi eGFR &lt; 45 ml\/ph\u00fat\/1,73m2<\/li>\n<li>\u0110\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng th\u1eadn th\u01b0\u1eddng xuy\u00ean khi d\u00f9ng Komboglyze XR 5mg\/500mg cho ng\u01b0\u1eddi cao tu\u1ed5i tr\u00ean 65 tu\u1ed5i<\/li>\n<li>Tr\u00e1nh s\u1eed d\u1ee5ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n suy gan ti\u1ebfn tri\u1ec3n<\/li>\n<li>Vi\u00eam t\u1ee5y c\u1ea5p \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng thu\u1ed1c, c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd tri\u1ec7u ch\u1ee9ng vi\u00eam t\u1ee5y<\/li>\n<li>Ng\u01b0ng s\u1eed d\u1ee5ng thu\u1ed1c n\u1ebfu b\u1ec7nh nh\u00e2n chu\u1ea9n b\u1ecb ph\u1eabu thu\u1eadt<\/li>\n<li>Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn nghi\u00eam tr\u1ecdng \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng thu\u1ed1c, th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng<\/li>\n<li>Tri\u1ec7u ch\u1ee9ng \u0111au kh\u1edbp \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng thu\u1ed1c<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o <strong>thu\u1ed1c ti\u1ec3u \u0111\u01b0\u1eddng <\/strong><strong>Komboglyze XR 5mg\/500mg<\/strong>: nh\u1ed3i m\u00e1u c\u01a1 tim, t\u0103ng nguy c\u01a1 tim m\u1ea1ch, t\u1ee5t \u0111\u01b0\u1eddng huy\u1ebft, bu\u1ed3n n\u00f4n, n\u00f4n, nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, nh\u1ee9c \u0111\u1ea7u, nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ec3u, qu\u00e1 m\u1eabn, gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u lympho to\u00e0n ph\u00e2n, h\u1ea1n ch\u1ebf s\u1ef1 h\u1ea5p thu vitamin B12.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<table>\n<tbody>\n<tr>\n<td width=\"312\">Thu\u1ed1c<\/td>\n<td width=\"312\">T\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Thu\u1ed1c \u1ee9c ch\u1ebf m\u1ea1nh CYP3A4\/5 (nefazodone, nelfinavir, ritonavir, saquinavir telithromycin, atazanavir, clarithromycin, indinavir, itraconazole,)<\/td>\n<td width=\"312\">L\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 saxagliptin trong c\u01a1 th\u1ec3<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Thu\u1ed1c ion d\u01b0\u01a1ng h\u00f3a (procainamide, quinine, ranitidine, triamterene, trimethoprim, amiloride, digoxin, morphine, quinidine, vancomycin)<\/td>\n<td width=\"312\">Theo d\u00f5i ch\u1eb7t ch\u1ebd v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi do c\u1ea1nh tranh qu\u00e1 tr\u00ecnh b\u00e0i ti\u1ebft tr\u00ean th\u1eadn<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">R\u01b0\u1ee3u<\/td>\n<td width=\"312\">Tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi, t\u0103ng nguy c\u01a1 nhi\u1ec5m acid lactic<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Ch\u1ea5t c\u1ea3n quang ch\u1ee9a iod<\/td>\n<td width=\"312\">T\u0103ng nguy c\u01a1 nhi\u1ec5m acid lactic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng Komboglyze XR 5mg\/500mg cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 s\u1ef1 \u1ea3nh h\u01b0\u1edfng c\u1ee7a Komboglyze XR 5mg\/500mg \u0111\u1ebfn ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>B\u1ec7nh nh\u00e2n g\u1eb7p t\u00ecnh tr\u1ea1ng qu\u00e1 li\u1ec1u Komboglyze XR 5mg\/500mg c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p l\u1ecdc m\u00e1u \u0111\u1ec3 lo\u1ea1i b\u1ecf l\u01b0\u1ee3ng thu\u1ed1c t\u00edch t\u1ee5 ra kh\u1ecfi c\u01a1 th\u1ec3.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Komboglyze XR 5mg\/500mg kh\u00f4ng n\u00ean \u0111\u1eb7t t\u1ea1i n\u01a1i g\u1ea7n khu vui ch\u01a1i c\u1ee7a tr\u1ebb nh\u1ecf. T\u1ed1t nh\u1ea5t, Komboglyze XR 5mg\/500mg n\u00ean \u0111\u01b0\u1ee3c \u0111\u1eb7t t\u1ea1i n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30 \u0111\u1ed9 C.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Komboglyze XR 5mg\/500mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/komboglyze-xr\/\">Komboglyze XR 5mg\/1000mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Saxagliptin 5 mg, Metformin hydroclorid 1000 mg, s\u1ea3n xu\u1ea5t b\u1edfi Bristol Myers Squibb, \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Komboglyze XR 5mg\/500mg do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/11\/HDSD-Komboglyze-XR-5mg500mg-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Komboglyze XR 5mg\/500mg \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tuyp 2, s\u1ea3n xu\u1ea5t b\u1edfi AstraZeneca Pharmaceuticals LP, USA, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18679-15<\/p>\n","protected":false},"author":1,"featured_media":146932,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-146558","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/146558","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=146558"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/146932"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=146558"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=146558"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=146558"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}