{"id":146549,"date":"2025-10-29T16:08:59","date_gmt":"2025-10-29T09:08:59","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=146549"},"modified":"2025-10-29T16:10:53","modified_gmt":"2025-10-29T09:10:53","slug":"glockner-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/glockner-5\/","title":{"rendered":"Glockner-5"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Glockner-5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi <\/b><b>C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa (Davipharm) <\/b><b>c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110020800 (S\u0110K c\u0169: VD-23921-15)<\/b><\/p>\n<h2>Glockner-5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Glockner-5<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Methimazol \u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026 5 mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Cellulose vi tinh th\u1ec3, natri starch glycolat, silicon dioxyd \u2026 v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110020800 (S\u0110K c\u0169: VD-23921-15)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Glockner-5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Methimazol (Thiamazol) \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p hormon tuy\u1ebfn gi\u00e1p b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf enzym peroxidase, ng\u0103n iod g\u1eafn v\u00e0o tyrosin c\u1ee7a thyroglobulin v\u00e0 c\u1eb7p iodotyrosin h\u00ecnh th\u00e0nh T3, T4. Nh\u1edd \u0111\u00f3, qu\u00e1 tr\u00ecnh t\u1ea1o hormon gi\u00e1p m\u1edbi b\u1ecb ch\u1eb7n.<\/p>\n<p>Thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hormon gi\u00e1p \u0111\u00e3 c\u00f3 trong m\u00e1u ho\u1eb7c hormon ngo\u1ea1i sinh, n\u00ean kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng v\u1edbi nhi\u1ec5m \u0111\u1ed9c gi\u00e1p do qu\u00e1 li\u1ec1u hormon. \u1ede b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 iod cao, t\u00e1c d\u1ee5ng c\u00f3 th\u1ec3 ch\u1eadm h\u01a1n.<\/p>\n<p>S\u1eed d\u1ee5ng Methimazol li\u1ec1u cao ho\u1eb7c k\u00e9o d\u00e0i c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hormon qu\u00e1 m\u1ee9c, k\u00edch th\u00edch tuy\u1ebfn y\u00ean t\u0103ng ti\u1ebft TSH v\u00e0 g\u00e2y ph\u00ec \u0111\u1ea1i tuy\u1ebfn gi\u00e1p. Khi ch\u1ee9c n\u0103ng gi\u00e1p \u1ed5n \u0111\u1ecbnh, c\u1ea7n gi\u1ea3m li\u1ec1u duy tr\u00ec ho\u1eb7c ph\u1ed1i h\u1ee3p hormon t\u1ed5ng h\u1ee3p \u0111\u1ec3 duy tr\u00ec c\u00e2n b\u1eb1ng.<\/p>\n<p>Methimazol m\u1ea1nh h\u01a1n nhi\u1ec1u so v\u1edbi c\u00e1c thu\u1ed1c nh\u00f3m thiouracil nh\u01b0ng kh\u00f4ng \u1ee9c ch\u1ebf chuy\u1ec3n T4 \u2192 T3 t\u1ea1i ngo\u1ea1i vi, do \u0111\u00f3 trong c\u01a1n nhi\u1ec5m \u0111\u1ed9c gi\u00e1p c\u1ea5p, propylthiouracil v\u1eabn th\u01b0\u1eddng \u0111\u01b0\u1ee3c \u01b0u ti\u00ean<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Sau khi u\u1ed1ng, Methimazol \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh v\u00e0 g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng ch\u1ec9 sau kho\u1ea3ng 1 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng \u01b0\u1edbc t\u00ednh x\u1ea5p x\u1ec9 93%.<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c t\u1eadp trung v\u1edbi n\u1ed3ng \u0111\u1ed9 cao t\u1ea1i tuy\u1ebfn gi\u00e1p \u2013 n\u01a1i ph\u00e1t huy t\u00e1c d\u1ee5ng ch\u00ednh. Kh\u1ea3 n\u0103ng g\u1eafn protein huy\u1ebft t\u01b0\u01a1ng th\u1ea5p. Methimazol c\u00f3 th\u1ec3 qua nhau thai v\u00e0 b\u00e0i ti\u1ebft m\u1ed9t ph\u1ea7n v\u00e0o s\u1eefa m\u1eb9.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu di\u1ec5n ra t\u1ea1i gan, t\u1ea1o th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh l\u00e0 3-methyl-2-thiohydantoin. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh t\u1eeb 5 \u0111\u1ebfn 6 gi\u1edd, nh\u01b0ng c\u00f3 th\u1ec3 k\u00e9o d\u00e0i \u1edf b\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng gan ho\u1eb7c th\u1eadn.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a, ch\u1ec9 m\u1ed9t ph\u1ea7n nh\u1ecf (&lt;10%) \u0111\u01b0\u1ee3c th\u1ea3i \u1edf d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/p>\n<h2>Thu\u1ed1c Glockner-5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng c\u01b0\u1eddng gi\u00e1p, bao g\u1ed3m c\u1ea3 b\u1ec7nh Graves\u2013Basedow.<\/p>\n<p>Chu\u1ea9n b\u1ecb tr\u01b0\u1edbc ph\u1eabu thu\u1eadt tuy\u1ebfn gi\u00e1p nh\u1eb1m \u0111\u01b0a b\u1ec7nh nh\u00e2n v\u1ec1 tr\u1ea1ng th\u00e1i b\u00ecnh gi\u00e1p, gi\u00fap h\u1ea1n ch\u1ebf nguy c\u01a1 c\u01a1n nhi\u1ec5m \u0111\u1ed9c gi\u00e1p trong v\u00e0 sau m\u1ed5.<\/p>\n<p>K\u1ebft h\u1ee3p trong \u0111i\u1ec1u tr\u1ecb iod ph\u00f3ng x\u1ea1, gi\u00fap ki\u1ec3m so\u00e1t hormon gi\u00e1p cho \u0111\u1ebfn khi iod ph\u00f3ng x\u1ea1 ph\u00e1t huy hi\u1ec7u qu\u1ea3 lo\u1ea1i b\u1ecf m\u00f4 tuy\u1ebfn gi\u00e1p.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb c\u01a1n nhi\u1ec5m \u0111\u1ed9c gi\u00e1p c\u1ea5p t\u00ednh, th\u01b0\u1eddng ph\u1ed1i h\u1ee3p c\u00f9ng thu\u1ed1c ch\u1eb9n beta v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 kh\u00e1c; tuy nhi\u00ean, propylthiouracil v\u1eabn \u0111\u01b0\u1ee3c \u01b0u ti\u00ean trong t\u00ecnh hu\u1ed1ng n\u00e0y.<\/p>\n<figure id=\"attachment_146550\" aria-describedby=\"caption-attachment-146550\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-146550\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Glockner-5.jpg\" alt=\"Glockner-5\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Glockner-5.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Glockner-5-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Glockner-5-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Glockner-5-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Glockner-5-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-146550\" class=\"wp-caption-text\">Thu\u1ed1c Glockner-5 c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng c\u01b0\u1eddng gi\u00e1p<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p><b><i>Ng\u01b0\u1eddi l\u1edbn v\u00e0 thanh thi\u1ebfu ni\u00ean<\/i><\/b><\/p>\n<p>C\u01b0\u1eddng gi\u00e1p nh\u1eb9: 15 mg\/ng\u00e0y \u2192 3 vi\u00ean, chia 3 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>C\u01b0\u1eddng gi\u00e1p v\u1eeba: 30\u201340 mg\/ng\u00e0y \u2192 6\u20138 vi\u00ean, chia 3 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>C\u01b0\u1eddng gi\u00e1p n\u1eb7ng: 60 mg\/ng\u00e0y \u2192 12 vi\u00ean, chia 3 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Li\u1ec1u duy tr\u00ec: 5\u201315 mg\/ng\u00e0y \u2192 1\u20133 vi\u00ean, chia 3 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng c\u1ea3i thi\u1ec7n sau 1\u20133 tu\u1ea7n v\u00e0 \u1ed5n \u0111\u1ecbnh sau 1\u20132 th\u00e1ng. Khi \u0111\u1ea1t b\u00ecnh gi\u00e1p, gi\u1ea3m li\u1ec1u d\u1ea7n \u0111\u1ec3 duy tr\u00ec. H\u1ea1n ch\u1ebf d\u00f9ng &gt;40 mg\/ng\u00e0y \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t.<\/p>\n<p><b><i>Tr\u1ebb em<\/i><\/b><\/p>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u: 0,4 mg\/kg\/ng\u00e0y \u2192 chia 3 l\u1ea7n, c\u00e1ch 8 gi\u1edd.<\/p>\n<p>Li\u1ec1u duy tr\u00ec: 0,2 mg\/kg\/ng\u00e0y \u2192 chia 3 l\u1ea7n, c\u00e1ch 8 gi\u1edd.<\/p>\n<p><b><i>C\u01a1n nhi\u1ec5m \u0111\u1ed9c gi\u00e1p<\/i><\/b><\/p>\n<p>Ng\u00e0y \u0111\u1ea7u: 15\u201320 mg m\u1ed7i 4 gi\u1edd \u2192 chia nhi\u1ec1u l\u1ea7n k\u1ebft h\u1ee3p \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 kh\u00e1c. Li\u1ec1u \u0111i\u1ec1u ch\u1ec9nh theo \u0111\u00e1p \u1ee9ng l\u00e2m s\u00e0ng.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng <strong>vi\u00ean n\u00e9n Glockner-5<\/strong> b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, chia \u0111\u1ec1u c\u00e1c li\u1ec1u trong ng\u00e0y (c\u00e1ch nhau ~8 gi\u1edd). C\u00f3 th\u1ec3 u\u1ed1ng 1\u20132 l\u1ea7n\/ng\u00e0y \u0111\u1ec3 t\u0103ng kh\u1ea3 n\u0103ng dung n\u1ea1p, hi\u1ec7u qu\u1ea3 c\u00f3 th\u1ec3 th\u1ea5p h\u01a1n.<\/p>\n<p>Ng\u01b0ng thu\u1ed1c 2\u20134 ng\u00e0y tr\u01b0\u1edbc khi d\u00f9ng iod ph\u00f3ng x\u1ea1, c\u00f3 th\u1ec3 d\u00f9ng l\u1ea1i 3\u20137 ng\u00e0y sau khi iod \u0111\u00e3 ph\u00e1t huy t\u00e1c d\u1ee5ng.<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb th\u01b0\u1eddng k\u00e9o d\u00e0i 6 th\u00e1ng \u2013 1\u20132 n\u0103m, t\u00f9y m\u1ee9c \u0111\u1ed9 b\u1ec7nh v\u00e0 \u0111\u00e1p \u1ee9ng.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Glockner-5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi Methimazol ho\u1eb7c t\u00e1 d\u01b0\u1ee3c c\u00f3 trong Glockner-5<\/p>\n<p>Ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa<\/p>\n<p>Suy gan n\u1eb7ng<\/p>\n<p>B\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n huy\u1ebft h\u1ecdc nghi\u00eam tr\u1ecdng nh\u01b0 suy t\u1ee7y ho\u1eb7c m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Vi\u1ec7c d\u00f9ng Methimazol ph\u1ea3i \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh v\u00e0 gi\u00e1m s\u00e1t b\u1edfi b\u00e1c s\u0129 chuy\u00ean khoa n\u1ed9i ti\u1ebft, nh\u1eb1m \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u ph\u00f9 h\u1ee3p theo \u0111\u00e1p \u1ee9ng c\u1ee7a t\u1eebng ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n<p>C\u1ea7n ki\u1ec3m tra s\u1ed1 l\u01b0\u1ee3ng v\u00e0 c\u00f4ng th\u1ee9c b\u1ea1ch c\u1ea7u tr\u01b0\u1edbc khi kh\u1edfi tr\u1ecb v\u00e0 theo d\u00f5i \u0111\u1ecbnh k\u1ef3 h\u00e0ng tu\u1ea7n trong 6 th\u00e1ng \u0111\u1ea7u, v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y gi\u1ea3m b\u1ea1ch c\u1ea7u ho\u1eb7c suy t\u1ee7y, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi l\u1edbn tu\u1ed5i ho\u1eb7c s\u1eed d\u1ee5ng li\u1ec1u cao.<\/p>\n<p>Theo d\u00f5i th\u1eddi gian prothrombin trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, nh\u1ea5t l\u00e0 khi xu\u1ea5t hi\u1ec7n d\u1ea5u hi\u1ec7u ch\u1ea3y m\u00e1u ho\u1eb7c chu\u1ea9n b\u1ecb ph\u1eabu thu\u1eadt.<\/p>\n<p>Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb d\u00e0i h\u1ea1n, c\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi c\u00e1c bi\u1ec3u hi\u1ec7n b\u1ea5t th\u01b0\u1eddng nh\u01b0 s\u1ed1t, \u0111au h\u1ecdng, v\u1ebft b\u1ea7m kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n \u2013 \u0111\u00e2y c\u00f3 th\u1ec3 l\u00e0 d\u1ea5u hi\u1ec7u c\u1ea3nh b\u00e1o gi\u1ea3m b\u1ea1ch c\u1ea7u n\u1eb7ng.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a Thiamazol th\u01b0\u1eddng li\u00ean quan \u0111\u1ebfn li\u1ec1u d\u00f9ng v\u00e0 ch\u1ee7 y\u1ebfu xu\u1ea5t hi\u1ec7n trong v\u00e0i tu\u1ea7n \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb. C\u00e1c ph\u1ea3n \u1ee9ng th\u01b0\u1eddng g\u1eb7p g\u1ed3m: ph\u00e1t ban, ng\u1ee9a, r\u1ee5ng t\u00f3c nh\u1eb9, nh\u1ee9c \u0111\u1ea7u, s\u1ed1t nh\u1eb9 ho\u1eb7c r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a.<\/p>\n<p>M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm c\u00f3 th\u1ec3 g\u1eb7p gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t, suy t\u1ee7y, gi\u1ea3m ti\u1ec3u c\u1ea7u, v\u00e0ng da \u1ee9 m\u1eadt, vi\u00eam gan, vi\u00eam kh\u1edbp, vi\u00eam m\u1ea1ch ho\u1eb7c vi\u00eam ph\u1ed5i k\u1ebd. N\u1ebfu xu\u1ea5t hi\u1ec7n s\u1ed1t, \u0111au h\u1ecdng, m\u1ec7t m\u1ecfi b\u1ea5t th\u01b0\u1eddng ho\u1eb7c d\u1ea5u hi\u1ec7u nhi\u1ec5m khu\u1ea9n, c\u1ea7n ng\u01b0ng thu\u1ed1c v\u00e0 b\u00e1o ngay cho b\u00e1c s\u0129 \u0111\u1ec3 ki\u1ec3m tra huy\u1ebft h\u1ecdc.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, h\u1ed7 tr\u1ee3 v\u00e0 thay th\u1ebf thu\u1ed1c kh\u00e1c khi c\u1ea7n thi\u1ebft.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Thu\u1ed1c ch\u1ee9a iod (amiodaron, KI&#8230;): l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a Thiamazol, c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/p>\n<p>Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u (nh\u01b0 warfarin): t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u do Thiamazol c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m prothrombin huy\u1ebft.<\/p>\n<p>Thu\u1ed1c ch\u1eb9n beta v\u00e0 glycosid tim: khi ch\u1ee9c n\u0103ng gi\u00e1p b\u00ecnh th\u01b0\u1eddng tr\u1edf l\u1ea1i, c\u1ea7n gi\u1ea3m li\u1ec1u c\u00e1c thu\u1ed1c n\u00e0y.<\/p>\n<p>Aminophyllin, theophyllin: c\u01b0\u1eddng gi\u00e1p l\u00e0m t\u0103ng th\u1ea3i tr\u1eeb; khi \u0111i\u1ec1u tr\u1ecb \u1ed5n \u0111\u1ecbnh v\u1edbi Thiamazol, c\u1ea7n gi\u1ea3m li\u1ec1u.<\/p>\n<p>Iod ph\u00f3ng x\u1ea1: n\u00ean ng\u1eebng Thiamazol \u00edt nh\u1ea5t 3\u20135 ng\u00e0y tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 tr\u00e1nh gi\u1ea3m h\u1ea5p thu iod v\u00e0o tuy\u1ebfn gi\u00e1p.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Thiamazol c\u00f3 th\u1ec3 qua nhau thai v\u00e0 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9, ti\u1ec1m \u1ea9n nguy c\u01a1 g\u00e2y b\u01b0\u1edbu c\u1ed5 ho\u1eb7c gi\u1ea3m n\u0103ng gi\u00e1p cho thai nhi, nh\u1ea5t l\u00e0 khi d\u00f9ng li\u1ec1u cao.<\/p>\n<p>Trong thai k\u1ef3, ch\u1ec9 s\u1eed d\u1ee5ng khi th\u1eadt c\u1ea7n thi\u1ebft v\u00e0 n\u00ean ch\u1ecdn li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 hi\u1ec7u qu\u1ea3. \u1ede giai \u0111o\u1ea1n \u0111\u1ea7u thai k\u1ef3, propylthiouracil \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o thay th\u1ebf v\u00ec \u00edt qua nhau thai h\u01a1n.<\/p>\n<p>N\u1ebfu \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Thiamazol, c\u1ea7n theo d\u00f5i s\u00e1t ch\u1ee9c n\u0103ng gi\u00e1p c\u1ee7a m\u1eb9 v\u00e0 thai. Khi cho con b\u00fa, ch\u1ec9 d\u00f9ng li\u1ec1u th\u1ea5p v\u00e0 theo d\u00f5i tr\u1ebb \u0111\u1ec3 ph\u00e1t hi\u1ec7n s\u1edbm d\u1ea5u hi\u1ec7u suy gi\u00e1p.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>M\u1ed9t s\u1ed1 ng\u01b0\u1eddi d\u00f9ng Thiamazol c\u00f3 th\u1ec3 g\u1eb7p ch\u00f3ng m\u1eb7t ho\u1eb7c bu\u1ed3n ng\u1ee7 nh\u1eb9, do \u0111\u00f3 n\u00ean th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c \u0111i\u1ec1u khi\u1ec3n m\u00e1y m\u00f3c cho \u0111\u1ebfn khi bi\u1ebft r\u00f5 ph\u1ea3n \u1ee9ng c\u1ee7a c\u01a1 th\u1ec3 v\u1edbi thu\u1ed1c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>D\u00f9ng qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au th\u01b0\u1ee3ng v\u1ecb, s\u1ed1t, ph\u00e1t ban, \u0111au kh\u1edbp, gi\u1ea3m b\u1ea1ch c\u1ea7u ho\u1eb7c suy t\u1ee7y.<\/p>\n<p>X\u1eed tr\u00ed g\u1ed3m: r\u1eeda d\u1ea1 d\u00e0y n\u1ebfu m\u1edbi u\u1ed1ng, \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 v\u00e0 theo d\u00f5i huy\u1ebft h\u1ecdc. Trong tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng, c\u00f3 th\u1ec3 c\u1ea7n truy\u1ec1n m\u00e1u, d\u00f9ng kh\u00e1ng sinh ho\u1eb7c corticoid t\u00f9y m\u1ee9c \u0111\u1ed9 t\u1ed5n th\u01b0\u01a1ng t\u1ee7y.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Glockner-5 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Glockner-5 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Glockner-5 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ee5<\/h2>\n<p><span style=\"font-size: 14.4px;\">Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Glockner-5 nh\u01b0:<\/span><\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/thyrozol-10mg\/\">Thyrozol 10m<\/a>g c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Thiamazole 10mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Merck Healthcare KGaA, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh c\u01b0\u1eddng gi\u00e1p<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Lertwattanarak R, Kunavisarut T, Sriussadaporn S (2022). Benefits of Long-Term Continuation of Low-Dose Methimazole Therapy in the Prevention of Recurrent Hyperthyroidism in Graves&#8217; Hyperthyroid Patients: A Randomized Prospective Controlled Study. Int J Endocrinol. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 10 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36267362\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36267362\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Glockner-5 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u1eb1m \u1ee9c ch\u1ebf s\u1ef1 h\u00ecnh th\u00e0nh hormon tuy\u1ebfn gi\u00e1p, trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh c\u01b0\u1eddng gi\u00e1p v\u00e0 c\u00e1c t\u00ecnh tr\u1ea1ng li\u00ean quan \u0111\u1ebfn t\u0103ng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a tuy\u1ebfn gi\u00e1p.<\/p>\n","protected":false},"author":1,"featured_media":146552,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-146549","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/146549","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=146549"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/146552"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=146549"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=146549"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=146549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}