{"id":146417,"date":"2025-10-28T12:32:03","date_gmt":"2025-10-28T05:32:03","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=146417"},"modified":"2025-10-29T08:03:21","modified_gmt":"2025-10-29T01:03:21","slug":"gliritdhg-500mg-5mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/gliritdhg-500mg-5mg\/","title":{"rendered":"GliritDHG 500mg\/5mg"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/b><a href=\"https:\/\/vnras.com\/drug\/\"><b> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a><b> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c GliritDHG 500mg\/5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi <\/b><b>C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c H\u1eadu Giang <\/b><b>c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110040723 (S\u0110K c\u0169: VD-24599-16)<\/b><\/p>\n<h2>GliritDHG 500mg\/5mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng GliritDHG 500mg\/5mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Metformin hydroclorid:&#8230;&#8230;&#8230;&#8230;&#8230;.500mg<\/li>\n<li>Glibenclamid:&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;5mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Avicel, lactose, PVP K30, croscarmellose sodium, magnesi stearat, HPMC, PVA, PEG 6000, titan dioxyd, talc, oxyd s\u1eaft v\u00e0ng.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110040723 (S\u0110K c\u0169: VD-24599-16)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c GliritDHG 500mg\/5mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>GliritDHG k\u1ebft h\u1ee3p hai ho\u1ea1t ch\u1ea5t ch\u00ednh l\u00e0 metformin v\u00e0 glibenclamid, c\u1ea3 hai c\u00f9ng ph\u1ed1i h\u1ee3p ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2.<\/p>\n<p>Metformin l\u00e0 ho\u1ea1t ch\u1ea5t thu\u1ed9c nh\u00f3m biguanid, c\u00f3 c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng ch\u1ee7 y\u1ebfu \u1edf ngo\u1ea1i vi. Thu\u1ed1c gi\u00fap t\u0103ng c\u01b0\u1eddng ti\u00eau th\u1ee5 glucose t\u1ea1i c\u01a1 v\u00e2n, \u0111\u1ed3ng th\u1eddi n\u00e2ng cao \u0111\u1ed9 nh\u1ea1y c\u1ea3m c\u1ee7a m\u00f4 v\u1edbi insulin. Ngo\u00e0i ra, metformin c\u00f2n \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh t\u00e2n t\u1ea1o \u0111\u01b0\u1eddng t\u1ea1i gan v\u00e0 l\u00e0m gi\u1ea3m h\u1ea5p thu glucose \u1edf ru\u1ed9t non.<\/p>\n<p>Kh\u00e1c v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c, metformin kh\u00f4ng l\u00e0m gi\u1ea3m \u0111\u01b0\u1eddng huy\u1ebft \u1edf ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng, m\u00e0 ch\u1ec9 h\u1ed7 tr\u1ee3 \u1ed5n \u0111\u1ecbnh \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2, \u0111\u1eb7c bi\u1ec7t khi c\u00f3 t\u00ecnh tr\u1ea1ng t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft sau \u0103n. Thu\u1ed1c hi\u1ebfm khi g\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, tr\u1eeb tr\u01b0\u1eddng h\u1ee3p nh\u1ecbn \u0103n k\u00e9o d\u00e0i ho\u1eb7c ph\u1ed1i h\u1ee3p c\u00f9ng c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c.<\/p>\n<p>Glibenclamid l\u00e0 m\u1ed9t sulfonylurea, k\u00edch th\u00edch t\u1ebf b\u00e0o beta tuy\u1ebfn t\u1ee5y ti\u1ebft insulin n\u1ed9i sinh, \u0111\u1ed3ng th\u1eddi gi\u1ea3m gi\u1ea3i ph\u00f3ng glucose t\u1eeb gan v\u00e0 t\u0103ng \u0111\u1ed9 nh\u1ea1y insulin t\u1ea1i t\u1ebf b\u00e0o ngo\u1ea1i vi. Khi \u0111i\u1ec1u tr\u1ecb d\u00e0i h\u1ea1n, n\u1ed3ng \u0111\u1ed9 insulin huy\u1ebft t\u01b0\u01a1ng tr\u1edf v\u1ec1 g\u1ea7n m\u1ee9c b\u00ecnh th\u01b0\u1eddng, nh\u01b0ng kh\u1ea3 n\u0103ng dung n\u1ea1p glucose v\u1eabn \u0111\u01b0\u1ee3c duy tr\u00ec.<br \/>\nS\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a metformin v\u00e0 glibenclamid t\u1ea1o hi\u1ec7u qu\u1ea3 b\u1ed5 tr\u1ee3, gi\u00fap ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft t\u1ed1t h\u01a1n so v\u1edbi d\u00f9ng \u0111\u01a1n tr\u1ecb li\u1ec7u khi \u0111\u01b0\u1eddng huy\u1ebft ch\u01b0a \u0111\u1ea1t m\u1ee5c ti\u00eau.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Metformin \u0111\u01b0\u1ee3c h\u1ea5p thu ch\u1eadm v\u00e0 kh\u00f4ng ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Khi u\u1ed1ng l\u00fac \u0111\u00f3i, sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i \u0111\u1ea1t kho\u1ea3ng 50\u201360%, tuy nhi\u00ean s\u1ef1 h\u1ea5p thu kh\u00f4ng t\u0103ng t\u01b0\u01a1ng \u1ee9ng v\u1edbi li\u1ec1u d\u00f9ng. Th\u1ee9c \u0103n c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u1ed1c \u0111\u1ed9 v\u00e0 m\u1ee9c \u0111\u1ed9 h\u1ea5p thu c\u1ee7a thu\u1ed1c.<br \/>\nMetformin h\u1ea7u nh\u01b0 kh\u00f4ng b\u1ecb chuy\u1ec3n h\u00f3a t\u1ea1i gan, \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua th\u1eadn \u1edf d\u1ea1ng c\u00f2n nguy\u00ean, v\u1edbi th\u1eddi gian b\u00e1n th\u1ea3i trong huy\u1ebft t\u01b0\u01a1ng t\u1eeb 1,5 \u0111\u1ebfn 4,5 gi\u1edd.<\/p>\n<p>Glibenclamid h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, d\u00f9ng c\u00f9ng th\u1ee9c \u0103n hay kh\u00f4ng c\u00f9ng \u0111\u1ec1u kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u1ea5p thu ho\u1ea1t ch\u1ea5t n\u00e0y. T\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft th\u01b0\u1eddng kh\u1edfi ph\u00e1t sau 45\u201360 ph\u00fat, v\u00e0 n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c trong kho\u1ea3ng 1,5 \u0111\u1ebfn 3 gi\u1edd sau khi d\u00f9ng. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 0,125 L\/kg v\u00e0 n\u1eeda \u0111\u1eddi thanh th\u1ea3i c\u1ee7a Glibenclamid l\u00e0 1,4\u20131,8 gi\u1edd (c\u00f3 th\u1ec3 k\u00e9o d\u00e0i \u1edf b\u1ec7nh nh\u00e2n suy gan ho\u1eb7c suy th\u1eadn). Glibenclamid chuy\u1ec3n h\u00f3a t\u1ea1i gan v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ra ngo\u00e0i qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n.<\/p>\n<h2>Thu\u1ed1c GliritDHG 500mg\/5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2, k\u1ebft h\u1ee3p v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 luy\u1ec7n t\u1eadp, \u0111\u1eb7c bi\u1ec7t khi \u0111\u01a1n tr\u1ecb li\u1ec7u b\u1eb1ng metformin ho\u1eb7c glibenclamid kh\u00f4ng \u0111\u1ee7 hi\u1ec7u qu\u1ea3.<\/p>\n<figure id=\"attachment_146418\" aria-describedby=\"caption-attachment-146418\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-146418\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/GliritDHG-500mg5mg.jpg\" alt=\"GliritDHG 500mg\/5mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/GliritDHG-500mg5mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/GliritDHG-500mg5mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/GliritDHG-500mg5mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/GliritDHG-500mg5mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/GliritDHG-500mg5mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-146418\" class=\"wp-caption-text\">Thu\u1ed1c GliritDHG 500mg\/5mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng t\u00edp 2<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Kh\u1edfi \u0111\u1ea7u: B\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c b\u1eaft \u0111\u1ea7u v\u1edbi 1 vi\u00ean m\u1ed7i ng\u00e0y (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng 500 mg metformin v\u00e0 5 mg glibenclamid), u\u1ed1ng trong ho\u1eb7c ngay sau b\u1eefa s\u00e1ng \u0111\u1ec3 gi\u1ea3m t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n<p>T\u0103ng li\u1ec1u: Li\u1ec1u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c n\u00e2ng d\u1ea7n t\u00f9y \u0111\u00e1p \u1ee9ng \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 kh\u1ea3 n\u0103ng ch\u1ecbu thu\u1ed1c c\u1ee7a b\u1ec7nh nh\u00e2n, m\u1ed7i l\u1ea7n t\u0103ng c\u00e1ch nhau 1\u20132 tu\u1ea7n.<\/p>\n<p>Gi\u1edbi h\u1ea1n li\u1ec1u: Kh\u00f4ng n\u00ean v\u01b0\u1ee3t qu\u00e1 2000 mg metformin v\u00e0 20 mg glibenclamid m\u1ed7i ng\u00e0y.<\/p>\n<p>Chuy\u1ec3n \u0111\u1ed5i t\u1eeb \u0111\u01a1n tr\u1ecb li\u1ec7u: Khi b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng metformin ho\u1eb7c sulfonylurea ri\u00eang l\u1ebb, li\u1ec1u kh\u1edfi \u0111\u1ea7u GliritDHG ph\u1ea3i b\u1eb1ng ho\u1eb7c th\u1ea5p h\u01a1n t\u1ed5ng li\u1ec1u c\u00e1c thu\u1ed1c tr\u01b0\u1edbc \u0111\u00f3, nh\u1eb1m tr\u00e1nh h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft qu\u00e1 m\u1ee9c.<\/p>\n<p><i>L\u01b0u \u00fd v\u1edbi b\u1ec7nh nh\u00e2n suy th\u1eadn:<\/i><\/p>\n<ul>\n<li>Thu\u1ed1c kh\u00f4ng s\u1eed d\u1ee5ng n\u1ebfu eGFR &lt; 30 mL\/ph\u00fat\/1,73 m\u00b2.<\/li>\n<li>Kh\u00f4ng n\u00ean b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb n\u1ebfu eGFR t\u1eeb 30\u201345 mL\/ph\u00fat\/1,73 m\u00b2, tr\u1eeb khi c\u00f3 \u0111\u00e1nh gi\u00e1 \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 l\u1ee3i \u00edch \u2013 nguy c\u01a1.<\/li>\n<li>Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn \u0111\u1ecbnh k\u1ef3 v\u00e0 ng\u1eebng thu\u1ed1c n\u1ebfu eGFR gi\u1ea3m d\u01b0\u1edbi 30 mL\/ph\u00fat\/1,73 m\u00b2.<\/li>\n<\/ul>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng nguy\u00ean <strong>vi\u00ean n\u00e9n GliritDHG 500mg\/5mg<\/strong> trong b\u1eefa \u0103n ho\u1eb7c ngay sau khi \u0103n \u0111\u1ec3 h\u1ea1n ch\u1ebf k\u00edch \u1ee9ng d\u1ea1 d\u00e0y<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c GliritDHG 500mg\/5mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Suy th\u1eadn n\u1eb7ng (eGFR &lt; 30 mL\/ph\u00fat\/1,73 m\u00b2).<\/p>\n<p>Toan chuy\u1ec3n h\u00f3a c\u1ea5p ho\u1eb7c m\u1ea1n, bao g\u1ed3m nhi\u1ec5m toan ceton do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/p>\n<p>Qu\u00e1 m\u1eabn v\u1edbi metformin, glibenclamid, sulfonamid ho\u1eb7c c\u00e1c th\u00e0nh ph\u1ea7n t\u00e1 d\u01b0\u1ee3c.<\/p>\n<p>Ng\u01b0\u1eddi \u0111ang nu\u00f4i con b\u1eb1ng s\u1eefa m\u1eb9<\/p>\n<p>Tr\u1ebb em<\/p>\n<p>Ph\u1ee5 n\u1eef mang thai<\/p>\n<p>T\u00ecnh tr\u1ea1ng d\u1ecb h\u00f3a c\u1ea5p, nhi\u1ec5m tr\u00f9ng n\u1eb7ng, b\u1ec7nh gan n\u1eb7ng, suy tim sung huy\u1ebft ho\u1eb7c b\u1ec7nh l\u00fd h\u00f4 h\u1ea5p g\u00e2y gi\u1ea3m oxy m\u00e1u.<\/p>\n<p>\u0110\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 1 ho\u1eb7c kh\u00f4ng \u1ed5n \u0111\u1ecbnh.<\/p>\n<p>Ti\u1ec1n s\u1eed h\u00f4n m\u00ea do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng ho\u1eb7c t\u1ed5n th\u01b0\u01a1ng gan\/th\u1eadn n\u1eb7ng.<\/p>\n<p>Nguy c\u01a1 nhi\u1ec5m acid lactic: nghi\u1ec7n r\u01b0\u1ee3u, thi\u1ebfu dinh d\u01b0\u1ee1ng, ch\u1ee5p X-quang c\u00f3 thu\u1ed1c c\u1ea3n quang iod (c\u1ea7n t\u1ea1m ng\u1eebng metformin).<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Duy tr\u00ec ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng h\u1ee3p l\u00fd v\u00e0 tu\u00e2n th\u1ee7 \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 tr\u00e1nh dao \u0111\u1ed9ng \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<p>C\u1ea7n theo d\u00f5i glucose huy\u1ebft, ch\u1ee9c n\u0103ng gan, th\u1eadn \u0111\u1ecbnh k\u1ef3 trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng.<\/p>\n<p>C\u1ea3nh gi\u00e1c v\u1edbi t\u00ecnh tr\u1ea1ng nhi\u1ec5m toan lactic \u2013 m\u1ed9t bi\u1ebfn ch\u1ee9ng hi\u1ebfm nh\u01b0ng nghi\u00eam tr\u1ecdng li\u00ean quan \u0111\u1ebfn metformin. D\u1eebng thu\u1ed1c v\u00e0 \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf ngay khi c\u00f3 tri\u1ec7u ch\u1ee9ng: m\u1ec7t m\u1ecfi, \u0111au c\u01a1, kh\u00f3 th\u1edf, l\u01a1 m\u01a1, \u0111au b\u1ee5ng.<\/p>\n<p>C\u1ea7n t\u1ea1m ng\u01b0ng s\u1eed d\u1ee5ng thu\u1ed1c tr\u01b0\u1edbc khi ti\u1ebfn h\u00e0nh c\u00e1c th\u1ee7 thu\u1eadt c\u00f3 d\u00f9ng thu\u1ed1c c\u1ea3n quang ch\u1ee9a iod ho\u1eb7c tr\u01b0\u1edbc khi ph\u1eabu thu\u1eadt l\u1edbn<\/p>\n<p>Tr\u00e1nh d\u00f9ng r\u01b0\u1ee3u trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb v\u00ec l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: Bu\u1ed3n n\u00f4n, n\u00f4n, \u0111\u1ea7y h\u01a1i, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, t\u00e1o b\u00f3n, ch\u00e1n \u0103n.<\/p>\n<p>\u00cdt g\u1eb7p: Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng da (m\u00e0y \u0111ay, ph\u00e1t ban), nh\u1ea1y c\u1ea3m \u00e1nh s\u00e1ng, gi\u1ea3m vitamin B12.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: H\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, vi\u00eam gan, v\u00e0ng da, thi\u1ebfu m\u00e1u, nhi\u1ec5m toan lactic, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c t\u1ea1m th\u1eddi.<\/p>\n<p><em><strong>X\u1eed tr\u00ed<\/strong><\/em><\/p>\n<p>U\u1ed1ng thu\u1ed1c trong b\u1eefa \u0103n \u0111\u1ec3 gi\u1ea3m k\u00edch \u1ee9ng ti\u00eau h\u00f3a.<\/p>\n<p>N\u1ebfu xu\u1ea5t hi\u1ec7n d\u1ea5u hi\u1ec7u h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, c\u1ea7n b\u1ed5 sung \u0111\u01b0\u1eddng (20\u201330 g) ho\u1eb7c th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129.<\/p>\n<p>Trong tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng ho\u1eb7c h\u00f4n m\u00ea, c\u1ea7n truy\u1ec1n glucose t\u0129nh m\u1ea1ch.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>T\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft: sulfonamid kh\u00e1c, salicylat, NSAID, fluoroquinolon, thu\u1ed1c ch\u1eb9n beta, c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf MAO, cloramphenicol, fenofibrat, probenecid\u2026<\/p>\n<p>Gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft: thu\u1ed1c l\u1ee3i ti\u1ec3u thiazid, corticosteroid, estrogen, thu\u1ed1c tr\u00e1nh thai c\u00f3 ph\u1ed1i h\u1ee3p estrogen\/gestagen, phenytoin, acid nicotinic, thu\u1ed1c ch\u1eb9n k\u00eanh calci, salbutamol\u2026<\/p>\n<p>M\u1ed9t s\u1ed1 thu\u1ed1c c\u00f3 th\u1ec3 t\u0103ng \u0111\u1ed9c t\u00ednh metformin ho\u1eb7c glibenclamid, c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng thu\u1ed1c \u1edf ph\u1ee5 n\u1eef c\u00f3 thai ho\u1eb7c \u0111ang cho con b\u00fa do nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 t\u00e1c \u0111\u1ed9ng kh\u00f4ng mong mu\u1ed1n tr\u00ean thai nhi.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Th\u1eadn tr\u1ecdng do nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi ho\u1eb7c gi\u1ea3m kh\u1ea3 n\u0103ng t\u1eadp trung.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u glibenclamid c\u00f3 th\u1ec3 g\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft nghi\u00eam tr\u1ecdng v\u1edbi c\u00e1c tri\u1ec7u ch\u1ee9ng: run r\u1ea9y, \u0111\u1ed5 m\u1ed3 h\u00f4i, k\u00edch th\u00edch, l\u00fa l\u1eabn, m\u1ea5t t\u1ec9nh t\u00e1o.<\/p>\n<p>X\u1eed tr\u00ed: U\u1ed1ng ngay dung d\u1ecbch \u0111\u01b0\u1eddng ho\u1eb7c \u0103n th\u1ee9c \u0103n ch\u1ee9a \u0111\u01b0\u1eddng; trong tr\u01b0\u1eddng h\u1ee3p h\u00f4n m\u00ea c\u1ea7n truy\u1ec1n t\u0129nh m\u1ea1ch dung d\u1ecbch glucose 20\u201330%.<\/p>\n<p>Qu\u00e1 li\u1ec1u metformin c\u00f3 th\u1ec3 g\u00e2y nhi\u1ec5m toan lactic, c\u1ea7n ng\u1eebng thu\u1ed1c ngay v\u00e0 ti\u1ebfn h\u00e0nh l\u1ecdc m\u00e1u \u0111\u1ec3 lo\u1ea1i b\u1ecf thu\u1ed1c kh\u1ecfi c\u01a1 th\u1ec3.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef GliritDHG 500mg\/5mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 GliritDHG 500mg\/5mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng GliritDHG 500mg\/5mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi GliritDHG 500mg\/5mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/hasanbest-500-5\/\">Hasanbest 500\/5<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Glibenclamid 5mg v\u00e0 Metformin hydroclorid 500mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Hasan &#8211; Dermapharm, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng t\u00edp 2<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/metovance\/\">Metovance<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Glibenclamid 5mg v\u00e0 Metformin hydroclorid 500mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00d4NG TY c\u1ed5 PH\u1ea8N D\u01af\u1ee2C PH\u1ea8M TR\u01af\u1edcNG TH\u1ecc, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng t\u00edp 2<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c GliritDHG 500mg\/5mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/To-huong-dan-su-dung-GliritDHG-500mg5mg-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 28 th\u00e1ng 10 n\u0103m 2025<\/li>\n<li>Gonzalez-Lopez C, Wojeck BS (2023). Role of metformin in the management of type 2 diabetes: recent advances. Pol Arch Intern Med. Truy c\u1eadp ng\u00e0y 28 th\u00e1ng 10 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37317976\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37317976\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c GliritDHG 500mg\/5mg ph\u1ed1i h\u1ee3p t\u1eeb hai ho\u1ea1t ch\u1ea5t h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft l\u00e0 Metformin v\u00e0 Glibenclamid, gi\u00fap ki\u1ec3m so\u00e1t n\u1ed3ng \u0111\u1ed9 glucose trong m\u00e1u th\u00f4ng qua hai c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng b\u1ed5 tr\u1ee3 nhau.<\/p>\n","protected":false},"author":1,"featured_media":146422,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-146417","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/146417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=146417"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/146422"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=146417"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=146417"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=146417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}