{"id":144867,"date":"2025-10-15T15:55:26","date_gmt":"2025-10-15T08:55:26","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=144867"},"modified":"2025-10-15T15:56:43","modified_gmt":"2025-10-15T08:56:43","slug":"tafsafe-25mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/tafsafe-25mg\/","title":{"rendered":"Tafsafe 25mg"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Tafsafe 25mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi RV Lifesciences Limited c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 <\/strong>890110415023 (S\u0110K c\u0169: VN3-250-19)<\/strong><\/p>\n

Tafsafe 25mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n

Th\u00e0nh ph\u1ea7n<\/h3>\n

Trong m\u1ed7i vi\u00ean u\u1ed1ng Tafsafe 25mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n

    \n
  • Tenofovir alafenamide (d\u01b0\u1edbi d\u1ea1ng Tenofovir alafenamide fumarate) ………………..25mg.<\/li>\n
  • T\u00e1 d\u01b0\u1ee3c: Lactose monohydrat, cellulose vi tinh th\u1ec3, croscarmellose natri, magnesi stearat, v\u00e0 opadry-II 85F120028 m\u00e0u v\u00e0ng.<\/li>\n<\/ul>\n

    D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n

    Tr\u00ecnh b\u00e0y<\/h3>\n

    S\u0110K: 890110415023 (S\u0110K c\u0169: VN3-250-19)<\/p>\n

    Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 Chai x 30 vi\u00ean<\/p>\n

    Xu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9<\/p>\n

    H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n

    T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Tafsafe 25mg<\/h2>\n

    C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n

    Tenofovir alafenamide (TAF) l\u00e0 m\u1ed9t ti\u1ec1n ch\u1ea5t phosphonamidate c\u1ee7a tenofovir, thu\u1ed9c nh\u00f3m t\u01b0\u01a1ng t\u1ef1 nucleotide. Sau khi \u0111\u01b0\u1ee3c h\u1ea5p thu, TAF \u0111\u01b0\u1ee3c th\u1ee7y ph\u00e2n n\u1ed9i b\u00e0o \u0111\u1ec3 gi\u1ea3i ph\u00f3ng tenofovir, m\u1ed9t d\u1eabn xu\u1ea5t c\u1ee7a 2′-deoxyadenosine monophosphate. Sau khi v\u00e0o c\u01a1 th\u1ec3, ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c h\u1ea5p thu ch\u1ee7 y\u1ebfu v\u00e0o t\u1ebf b\u00e0o gan nh\u1edd khu\u1ebfch t\u00e1n th\u1ee5 \u0111\u1ed9ng v\u00e0 qua c\u00e1c k\u00eanh v\u1eadn chuy\u1ec3n OATP1B1, OATP1B3.<\/p>\n

    T\u1ea1i gan, n\u00f3 \u0111\u01b0\u1ee3c enzyme carboxylesterase-1 th\u1ee7y ph\u00e2n t\u1ea1o th\u00e0nh Tenofovir, sau \u0111\u00f3 \u0111\u01b0\u1ee3c phosphoryl h\u00f3a th\u00e0nh Tenofovir diphosphate \u2013 d\u1ea1ng ho\u1ea1t t\u00ednh c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf s\u1ef1 sao ch\u00e9p ng\u01b0\u1ee3c c\u1ee7a HBV b\u1eb1ng c\u00e1ch g\u1eafn v\u00e0o DNA virus, g\u00e2y ng\u1eaft chu\u1ed7i t\u1ed5ng h\u1ee3p DNA.<\/p>\n

    Nh\u1edd \u0111\u00f3, Tenofovir alafenamide l\u00e0m gi\u1ea3m s\u1ef1 nh\u00e2n l\u00ean c\u1ee7a virus vi\u00eam gan B v\u00e0 c\u1ea3i thi\u1ec7n c\u00e1c ch\u1ec9 s\u1ed1 men gan. Tenofovir c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng ch\u1ecdn l\u1ecdc tr\u00ean HBV v\u00e0 HIV-1\/HIV-2, h\u1ea7u nh\u01b0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn DNA polymerase c\u1ee7a t\u1ebf b\u00e0o ng\u01b0\u1eddi, h\u1ea1n ch\u1ebf \u0111\u1ed9c t\u00ednh tr\u00ean ty th\u1ec3.<\/p>\n

    \u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n

    H\u1ea5p thu: Sau khi u\u1ed1ng, Tenofovir alafenamide \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng n\u1eeda gi\u1edd. Khi d\u00f9ng c\u00f9ng b\u1eefa \u0103n nhi\u1ec1u ch\u1ea5t b\u00e9o, kh\u1ea3 n\u0103ng h\u1ea5p thu t\u0103ng kho\u1ea3ng 65% so v\u1edbi l\u00fac \u0111\u00f3i.<\/p>\n

    Ph\u00e2n b\u1ed1: Kho\u1ea3ng 80% Tenofovir alafenamide g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng; trong khi Tenofovir ch\u1ec9 g\u1eafn k\u1ebft d\u01b0\u1edbi 1%.<\/p>\n

    Chuy\u1ec3n h\u00f3a: Thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu t\u1ea1i gan b\u1edfi carboxylesterase-1 v\u00e0 trong t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch b\u1edfi cathepsin A \u0111\u1ec3 t\u1ea1o th\u00e0nh Tenofovir, sau \u0111\u00f3 \u0111\u01b0\u1ee3c phosphoryl h\u00f3a th\u00e0nh Tenofovir diphosphate \u2013 d\u1ea1ng c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng virus.<\/p>\n

    Th\u1ea3i tr\u1eeb: L\u01b0\u1ee3ng tenofovir alafenamide ch\u01b0a chuy\u1ec3n h\u00f3a b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u chi\u1ebfm d\u01b0\u1edbi 1%. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh c\u1ee7a tenofovir alafenamide kho\u1ea3ng 0,5 gi\u1edd, trong khi tenofovir c\u00f3 th\u1eddi gian b\u00e1n th\u1ea3i k\u00e9o d\u00e0i h\u01a1n 32 gi\u1edd, gi\u00fap duy tr\u00ec hi\u1ec7u qu\u1ea3 kh\u00e1ng virus l\u00e2u d\u00e0i. Qu\u00e1 tr\u00ecnh th\u1ea3i tr\u1eeb di\u1ec5n ra qua l\u1ecdc c\u1ea7u th\u1eadn v\u00e0 b\u00e0i ti\u1ebft \u1edf \u1ed1ng th\u1eadn<\/p>\n

    Thu\u1ed1c Tafsafe 25mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n

    Ng\u01b0\u1eddi l\u1edbn v\u00e0 thanh thi\u1ebfu ni\u00ean (\u226512 tu\u1ed5i, \u226535 kg) m\u1eafc vi\u00eam gan B m\u1ea1n t\u00ednh.<\/p>\n

    \"Tafsafe
    Thu\u1ed1c Tafsafe 25mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B m\u1ea1n t\u00ednh<\/figcaption><\/figure>\n

    Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n

    Li\u1ec1u d\u00f9ng<\/h3>\n\n\n\n\n\n\n\n\n\n
    \u0110\u1ed1i t\u01b0\u1ee3ng<\/strong><\/td>\nLi\u1ec1u khuy\u1ebfn c\u00e1o<\/strong><\/td>\n<\/tr>\n
    Ng\u01b0\u1eddi l\u1edbn v\u00e0 thanh thi\u1ebfu ni\u00ean \u226512 tu\u1ed5i, \u226535 kg<\/td>\n1 vi\u00ean\/ng\u00e0y<\/td>\n<\/tr>\n
    Ng\u01b0\u1eddi cao tu\u1ed5i<\/td>\nKh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u<\/td>\n<\/tr>\n
    Suy th\u1eadn (CrCl \u226515 mL\/ph\u00fat ho\u1eb7c b\u1ec7nh nh\u00e2n ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o<\/td>\nKh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u, n\u00ean u\u1ed1ng sau bu\u1ed5i ch\u1ea1y th\u1eadn<\/td>\n<\/tr>\n
    Suy th\u1eadn n\u1eb7ng (CrCl <15 mL\/ph\u00fat, kh\u00f4ng ch\u1ea1y th\u1eadn)<\/td>\nKh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng<\/td>\n<\/tr>\n
    Suy gan<\/td>\nD\u00f9ng li\u1ec1u th\u00f4ng th\u01b0\u1eddng<\/td>\n<\/tr>\n
    Tr\u1ebb <12 tu\u1ed5i ho\u1eb7c <35 kg<\/td>\nCh\u01b0a c\u00f3 d\u1eef li\u1ec7u an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Ng\u1eebng \u0111i\u1ec1u tr\u1ecb<\/strong><\/em><\/p>\n

    B\u1ec7nh nh\u00e2n HBeAg d\u01b0\u01a1ng t\u00ednh kh\u00f4ng x\u01a1 gan: n\u00ean ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb \u00edt nh\u1ea5t 6\u201312 th\u00e1ng sau khi chuy\u1ec3n \u0111\u1ed5i huy\u1ebft thanh HBe, ho\u1eb7c cho \u0111\u1ebfn khi chuy\u1ec3n \u0111\u1ed5i HBs.<\/p>\n

    B\u1ec7nh nh\u00e2n HBeAg \u00e2m t\u00ednh kh\u00f4ng x\u01a1 gan: n\u00ean duy tr\u00ec cho \u0111\u1ebfn khi \u0111\u1ea1t chuy\u1ec3n \u0111\u1ed5i HBs ho\u1eb7c c\u00f3 d\u1ea5u hi\u1ec7u m\u1ea5t \u0111\u00e1p \u1ee9ng. N\u1ebfu \u0111i\u1ec1u tr\u1ecb tr\u00ean 2 n\u0103m, c\u1ea7n \u0111\u00e1nh gi\u00e1 l\u1ea1i \u0111\u1ecbnh k\u1ef3 \u0111\u1ec3 xem x\u00e9t t\u00ednh ph\u00f9 h\u1ee3p.<\/p>\n

    Qu\u00ean li\u1ec1u<\/strong><\/em><\/p>\n

    N\u1ebfu qu\u00ean u\u1ed1ng thu\u1ed1c v\u00e0 th\u1eddi gian tr\u00f4i qua d\u01b0\u1edbi 18 gi\u1edd so v\u1edbi li\u1ec1u th\u00f4ng th\u01b0\u1eddng, ng\u01b0\u1eddi b\u1ec7nh n\u00ean d\u00f9ng Tenofovir alafenamide ngay khi nh\u1edb ra, r\u1ed3i ti\u1ebfp t\u1ee5c c\u00e1c li\u1ec1u k\u1ebf ti\u1ebfp theo \u0111\u00fang l\u1ecbch.<\/p>\n

    Tr\u01b0\u1eddng h\u1ee3p \u0111\u00e3 qu\u00e1 18 gi\u1edd, b\u1ecf qua li\u1ec1u \u0111\u00e3 qu\u00ean v\u00e0 d\u00f9ng li\u1ec1u ti\u1ebfp theo nh\u01b0 b\u00ecnh th\u01b0\u1eddng.<\/p>\n

    N\u1ebfu trong v\u00f2ng\u00a0 60 ph\u00fat sau khi d\u00f9ng Tenofovir alafenamide, c\u1ea7n u\u1ed1ng th\u00eam m\u1ed9t vi\u00ean kh\u00e1c<\/p>\n

    C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n

    \u0110\u1ec3 t\u0103ng h\u1ea5p thu, n\u00ean u\u1ed1ng vi\u00ean n\u00e9n Tafsafe 25mg<\/strong> v\u1edbi b\u1eefa \u0103n<\/p>\n

    Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Tafsafe 25mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n

    Kh\u00f4ng d\u00f9ng Tafsafe 25mg cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi Tenofovir alafenamide ho\u1eb7c v\u1edbi b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o trong thu\u1ed1c.
    \nB\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n di truy\u1ec1n hi\u1ebfm g\u1eb7p nh\u01b0 kh\u00f4ng dung n\u1ea1p galactose, thi\u1ebfu h\u1ee5t Lapp lactase ho\u1eb7c k\u00e9m h\u1ea5p thu glucose-galactose kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng do thu\u1ed1c c\u00f3 ch\u1ee9a lactose.<\/p>\n

    L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n

    Th\u1eadn tr\u1ecdng<\/h3>\n

    Nguy c\u01a1 l\u00e2y truy\u1ec1n: Thu\u1ed1c kh\u00f4ng ph\u00f2ng ng\u1eeba l\u00e2y truy\u1ec1n HBV qua \u0111\u01b0\u1eddng m\u00e1u ho\u1eb7c t\u00ecnh d\u1ee5c; ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p b\u1ea3o v\u1ec7 th\u00edch h\u1ee3p.<\/p>\n

    B\u1ec7nh nh\u00e2n gan m\u1ea5t b\u00f9: Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 tr\u00ean b\u1ec7nh nh\u00e2n c\u00f3 \u0111i\u1ec3m Child-Pugh > 9. C\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ee9c n\u0103ng gan v\u00e0 th\u1eadn.<\/p>\n

    B\u00f9ng ph\u00e1t vi\u00eam gan: C\u00f3 th\u1ec3 x\u1ea3y ra trong ho\u1eb7c sau khi ng\u1eebng thu\u1ed1c; c\u1ea7n theo d\u00f5i men gan \u0111\u1ecbnh k\u1ef3 \u00edt nh\u1ea5t 6 th\u00e1ng sau khi d\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/p>\n

    \u0110\u1ed9c t\u00ednh th\u1eadn: M\u1eb7c d\u00f9 nguy c\u01a1 th\u1ea5p h\u01a1n so v\u1edbi Tenofovir disoproxil fumarate, v\u1eabn c\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn.<\/p>\n

    Tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Tafsafe, c\u1ea7n ki\u1ec3m tra t\u00ecnh tr\u1ea1ng nhi\u1ec5m HIV \u1edf m\u1ecdi b\u1ec7nh nh\u00e2n nhi\u1ec5m HBV m\u00e0 ch\u01b0a bi\u1ebft t\u00ecnh tr\u1ea1ng n\u00e0y. N\u1ebfu x\u00e9t nghi\u1ec7m cho th\u1ea5y nhi\u1ec5m \u0111\u1ed3ng th\u1eddi HBV v\u00e0 HIV, Tafsafe ph\u1ea3i \u0111\u01b0\u1ee3c d\u00f9ng k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng retrovirus kh\u00e1c theo ph\u00e1c \u0111\u1ed3 th\u00edch h\u1ee3p nh\u1eb1m \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb HIV v\u00e0 tr\u00e1nh t\u00ecnh tr\u1ea1ng kh\u00e1ng thu\u1ed1c<\/p>\n

    T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n

    Trong hai nghi\u00ean c\u1ee9u giai \u0111o\u1ea1n 3 tr\u00ean 866 b\u1ec7nh nh\u00e2n HBV, Tenofovir alafenamide 25 mg d\u00f9ng m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y cho th\u1ea5y c\u00e1c ph\u1ea3n \u1ee9ng th\u01b0\u1eddng g\u1eb7p l\u00e0 12% b\u1ec7nh nh\u00e2n g\u1eb7p nh\u1ee9c \u0111\u1ea7u, 6% b\u1ecb bu\u1ed3n n\u00f4n v\u00e0 6% m\u1ec7t m\u1ecfi. Sau Tu\u1ea7n 96, kh\u00f4ng ghi nh\u1eadn th\u00eam ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i n\u00e0o m\u1edbi trong th\u1eddi gian theo d\u00f5i ti\u1ebfp theo \u0111\u1ebfn Tu\u1ea7n 120. Kh\u00f4ng n\u00ean d\u00f9ng Tafsafe chung v\u1edbi c\u00e1c thu\u1ed1c ch\u1ee9a Tenofovir ho\u1eb7c Adefovir.<\/p>\n

    T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n

    Tafsafe kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng c\u00f9ng c\u00e1c s\u1ea3n ph\u1ea9m ch\u1ee9a Tenofovir alafenamide, Tenofovir disoproxil fumarate ho\u1eb7c Adefovir dipivoxil \u0111\u1ec3 tr\u00e1nh tr\u00f9ng ho\u1ea1t ch\u1ea5t.<\/p>\n

    M\u1ed9t s\u1ed1 thu\u1ed1c nh\u01b0 carbamazepine, oxcarbazepine, phenobarbital, phenytoin, rifampicin, rifabutin, rifapentine v\u00e0 St. John\u2019s wort c\u00f3 th\u1ec3 l\u00e0m thu\u1ed1c gi\u1ea3m t\u00e1c d\u1ee5ng, n\u00ean tr\u00e1nh ph\u1ed1i h\u1ee3p.<\/p>\n

    Ng\u01b0\u1ee3c l\u1ea1i, c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf P-gp m\u1ea1nh nh\u01b0 itraconazole ho\u1eb7c ketoconazole c\u00f3 th\u1ec3 l\u00e0m thu\u1ed1c t\u0103ng n\u1ed3ng \u0111\u1ed9 trong c\u01a1 th\u1ec3, do \u0111\u00f3 c\u0169ng kh\u00f4ng n\u00ean d\u00f9ng c\u00f9ng.<\/p>\n

    L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n

    Ph\u1ee5 n\u1eef c\u00f3 thai<\/strong><\/em><\/p>\n

    Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u v\u1ec1 \u0111\u1ed9 an to\u00e0n \u1edf ph\u1ee5 n\u1eef mang thai. Tuy nhi\u00ean, kinh nghi\u1ec7m t\u1eeb thu\u1ed1c t\u01b0\u01a1ng t\u1ef1 (tenofovir disoproxil fumarate) cho th\u1ea5y kh\u00f4ng l\u00e0m t\u0103ng nguy c\u01a1 d\u1ecb t\u1eadt b\u1ea9m sinh. C\u00f3 th\u1ec3 xem x\u00e9t s\u1eed d\u1ee5ng n\u1ebfu l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1.<\/p>\n

    Ph\u1ee5 n\u1eef cho con b\u00fa<\/strong><\/em><\/p>\n

    Ch\u01b0a r\u00f5 tenofovir alafenamide c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng, nh\u01b0ng tenofovir c\u00f3 th\u1ec3 \u0111i qua s\u1eefa \u0111\u1ed9ng v\u1eadt. Do \u0111\u00f3, kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c khi \u0111ang cho con b\u00fa \u0111\u1ec3 tr\u00e1nh r\u1ee7i ro cho tr\u1ebb.<\/p>\n

    Kh\u1ea3 n\u0103ng sinh s\u1ea3n<\/strong><\/em><\/p>\n

    Kh\u00f4ng c\u00f3 d\u1eef li\u1ec7u tr\u00ean ng\u01b0\u1eddi cho th\u1ea5y thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng sinh s\u1ea3n; nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt kh\u00f4ng ph\u00e1t hi\u1ec7n t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i.<\/p>\n

    L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n

    H\u1ea7u nh\u01b0 kh\u00f4ng c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 n\u00e0o \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe ho\u1eb7c c\u00f4ng vi\u1ec7c c\u1ea7n d\u00f9ng m\u00e1y m\u00f3c khi u\u1ed1ng Tafsafe 25mg. Tuy nhi\u00ean, n\u1ebfu c\u1ea3m th\u1ea5y ch\u00f3ng m\u1eb7t ho\u1eb7c m\u1ec7t m\u1ecfi, ng\u01b0\u1eddi d\u00f9ng n\u00ean th\u1eadn tr\u1ecdng khi th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c \u0111\u00f2i h\u1ecfi s\u1ef1 t\u1ec9nh t\u00e1o.<\/p>\n

    Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n

    Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c Tafsafe 25mg \u0111\u1eb7c hi\u1ec7u. N\u1ebfu u\u1ed1ng qu\u00e1 li\u1ec1u, c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd c\u00e1c d\u1ea5u hi\u1ec7u sinh t\u1ed3n v\u00e0 tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng, \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 to\u00e0n th\u00e2n.<\/p>\n

    Tenofovir c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1ea3i b\u1edbt qua ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o v\u1edbi hi\u1ec7u su\u1ea5t kho\u1ea3ng 54%. Hi\u1ec7n ch\u01b0a c\u00f3 th\u00f4ng tin v\u1ec1 vi\u1ec7c lo\u1ea1i b\u1ecf thu\u1ed1c b\u1eb1ng th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c<\/p>\n

    B\u1ea3o qu\u1ea3n<\/h3>\n

    Gi\u1eef Tafsafe 25mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (<30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n

    Kh\u00f4ng \u0111\u1ec3 Tafsafe 25mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n

    Kh\u00f4ng s\u1eed d\u1ee5ng Tafsafe 25mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n

    S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n

    Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Tafsafe 25mg nh\u01b0:<\/p>\n

    Hepa-Taf 25mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Tenofovir alafenamide 25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH BRV Healthcare, \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B<\/p>\n

    Tenofovir Alafenamide 25mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Tenofovir alafenamide 25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m qu\u1ed1c t\u1ebf CT Pharma, \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B<\/p>\n

    T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n
      \n
    1. T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Tafsafe 25mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 t\u1ea1i \u0111\u00e2y.<\/a> Truy c\u1eadp ng\u00e0y 15 th\u00e1ng 10 n\u0103m 2025<\/li>\n
    2. Wassner C, Bradley N, Lee Y (2020). A Review and Clinical Understanding of Tenofovir: Tenofovir Disoproxil Fumarate versus Tenofovir Alafenamide. J Int Assoc Provid AIDS Care. Truy c\u1eadp ng\u00e0y 15 th\u00e1ng 10 n\u0103m 2025 t\u1eeb: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7163232\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

      Thu\u1ed1c Tafsafe 25mg l\u00e0 thu\u1ed1c kh\u00e1ng virus thu\u1ed9c nh\u00f3m nucleotid, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb vi\u00eam gan si\u00eau vi B m\u1ea1n t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 thanh thi\u1ebfu ni\u00ean t\u1eeb 12 tu\u1ed5i t\u1eeb 35kg<\/p>\n","protected":false},"author":1,"featured_media":144871,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-144867","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/144867","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=144867"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/144871"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=144867"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=144867"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=144867"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}