{"id":144697,"date":"2025-10-17T14:03:27","date_gmt":"2025-10-17T07:03:27","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=144697"},"modified":"2025-10-17T14:08:31","modified_gmt":"2025-10-17T07:08:31","slug":"natidof-8","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/natidof-8\/","title":{"rendered":"Natidof 8"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/natidof-8\/\">Natidof 8<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n S.P.M, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110046000 (S\u0110K c\u0169: VD-23868-15).<\/strong><\/p>\n<h2>Natidof 8 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Natidof 8<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Thiocolchicosid 8mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110046000 (S\u0110K c\u0169: VD-23868-15)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Natidof 8<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Thiocolchicosid l\u00e0 ch\u1ea5t t\u1ed5ng h\u1ee3p t\u1eeb glucoside thi\u00ean nhi\u00ean c\u00f3 ch\u1ee9a l\u01b0u hu\u1ef3nh.<\/p>\n<p>Thiocolchicosid li\u00ean k\u1ebft v\u1edbi GABA-A l\u00e0m gi\u00e3n c\u01a1 b\u1eafp tr\u00ean v\u1ecb tr\u00ed x\u01b0\u01a1ng s\u1ed1ng nh\u1edd ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh (ch\u1ea5t glucuronid h\u00f3a). Ngo\u00e0i ra thu\u1ed1c c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng kh\u00e1ng vi\u00eam, gi\u1ea3m \u0111au \u1edf v\u00f9ng x\u01b0\u01a1ng s\u1ed1ng c\u00f3 t\u1ed5n th\u01b0\u01a1ng. Tuy nhi\u00ean, ho\u1ea1t ch\u1ea5t n\u00e0y kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng an th\u1ea7n.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng c\u1ee7a Thiocolchicosid kho\u1ea3ng 25%, th\u1ec3 hi\u1ec7n t\u00e1c d\u1ee5ng sau 1-2 gi\u1edd s\u1eed d\u1ee5ng, n\u1ed3ng \u0111\u1ed9 thu\u1ed1c \u0111\u1ea1t \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 4,5 gi\u1edd.<\/p>\n<p>Ph\u00e2n b\u1ed1: Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 bi\u1ec3u ki\u1ebfn kho\u1ea3ng 42,7L<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Thiocolchicosid chuy\u1ec3n h\u00f3a th\u00e0nh 3 ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh<\/p>\n<p>Th\u1ea3i tr\u1eeb: Thu\u1ed1c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua ph\u00e2n (79%) v\u00e0 n\u01b0\u1edbc ti\u1ec3u (20%), th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 7,7 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Natidof 8 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c <strong>Natidof 8<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh d\u00f9ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n g\u1eb7p t\u00ecnh tr\u1ea1ng tho\u00e1i h\u00f3a \u0111\u1ed1t s\u1ed1ng, r\u1ed1i lo\u1ea1n t\u01b0 th\u1ebf c\u1ed9t s\u1ed1ng (\u0111au th\u1eaft l\u01b0ng, \u0111au l\u01b0ng, v\u1eb9o c\u1ed5)<\/li>\n<li>B\u1ec7nh nh\u00e2n g\u1eb7p ch\u1ea5n th\u01b0\u01a1ng v\u00e0 th\u1ea7n kinh (xu\u1ea5t hi\u1ec7n c\u01a1n co c\u1ee9ng)<\/li>\n<li>B\u1ec7nh nh\u00e2n trong giai \u0111o\u1ea1n ph\u1ee5c h\u1ed3i ch\u1ee9c n\u0103ng<\/li>\n<\/ul>\n<figure id=\"attachment_145222\" aria-describedby=\"caption-attachment-145222\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-145222\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Natidof-8.jpg\" alt=\"Natidof 8 \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng tho\u00e1i h\u00f3a \u0111\u1ed1t s\u1ed1ng, r\u1ed1i lo\u1ea1n t\u01b0 th\u1ebf c\u1ed9t s\u1ed1ng (\u0111au th\u1eaft l\u01b0ng, \u0111au l\u01b0ng, v\u1eb9o c\u1ed5)\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Natidof-8.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Natidof-8-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Natidof-8-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Natidof-8-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Natidof-8-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-145222\" class=\"wp-caption-text\">Natidof 8 \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng tho\u00e1i h\u00f3a \u0111\u1ed1t s\u1ed1ng, r\u1ed1i lo\u1ea1n t\u01b0 th\u1ebf c\u1ed9t s\u1ed1ng (\u0111au th\u1eaft l\u01b0ng, \u0111au l\u01b0ng, v\u1eb9o c\u1ed5)<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Natidof 8<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn: 16 mg\/ng\u00e0y<\/li>\n<li>\u0110\u1ee3t c\u1ea5p t\u00ednh: 32-48 mg\/ng\u00e0y<\/li>\n<\/ul>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c Natidof 8 d\u1ea1ng vi\u00ean n\u00e9n, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Natidof 8 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Natidof 8 cho b\u1ec7nh nh\u00e2n m\u1eabn c\u1ea3m v\u1edbi Thiocolchicosid ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o trong thu\u1ed1c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Natidof 8<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng Natidof 8 n\u1ebfu xu\u1ea5t hi\u1ec7n ti\u00eau ch\u1ea3y c\u1ea7n gi\u1ea3m li\u1ec1u n\u1ebfu c\u1ea7n<\/li>\n<li>Kh\u00f4ng d\u00f9ng thu\u1ed1c qu\u00e1 li\u1ec1u l\u01b0\u1ee3ng khuy\u1ebfn c\u00e1o c\u1ee7a chuy\u00ean gia y t\u1ebf<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng Natidof 8 khi h\u1ebft h\u1ea1n d\u00f9ng<\/li>\n<li>B\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u01b0\u1ee3c t\u1ef1 \u00fd \u0111i\u1ec1u ch\u1ec9nh gi\u1ea3m ho\u1eb7c t\u0103ng li\u1ec1u d\u00f9ng, c\u00f3 th\u1ec3 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c v\u00e0 t\u0103ng \u0111\u1ed9c t\u00ednh.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>M\u1ed9t s\u1ed1 ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng Natidof 8: n\u1ed5i m\u1ea9n ngo\u00e0i da, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, \u0111au d\u1ea1 d\u00e0y, ti\u00eau ch\u1ea3y<\/p>\n<p>B\u1ec7nh nh\u00e2n c\u1ea7n th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u1ec1 t\u1ea5t c\u1ea3 c\u00e1c tri\u1ec7u ch\u1ee9ng b\u1ea5t l\u1ee3i g\u1eb7p ph\u1ea3i trong giai \u0111o\u1ea1n \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Hi\u1ec7n nay ch\u01b0a c\u00f3 b\u00e1o c\u00e1o v\u1ec1 t\u01b0\u01a1ng t\u00e1c b\u1ea5t l\u1ee3i khi d\u00f9ng \u0111\u1ed3ng th\u1eddi Natidof 8 v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c.<\/p>\n<p>Vi\u1ec7c th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u1ec1 c\u00e1c thu\u1ed1c \u0111ang d\u00f9ng l\u00e0 c\u1ea7n thi\u1ebft \u0111\u1ec3 tr\u00e1nh t\u01b0\u01a1ng t\u00e1c b\u1ea5t l\u1ee3i v\u1edbi Natidof 8<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng d\u00f9ng Natidof 8 cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c Natidof 8 c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7, th\u1eadn tr\u1ecdng khi d\u00f9ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Hi\u1ec7n nay ch\u01b0a c\u00f3 b\u00e1o c\u00e1o v\u1ec1 t\u00ecnh tr\u1ea1ng qu\u00e1 li\u1ec1u Natidof 8. B\u1ec7nh nh\u00e2n d\u00f9ng qu\u00e1 li\u1ec1u h\u01b0\u1edbng d\u1eabn c\u1ee7a b\u00e1c s\u0129 c\u00f3 th\u1ec3 g\u00e2y nguy hi\u1ec3m \u0111\u1ebfn s\u1ee9c kh\u1ecfe, c\u1ea7n \u0111\u01b0\u1ee3c \u0111\u01b0a t\u1edbi c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 x\u1eed tr\u00ed k\u1ecbp th\u1eddi.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n Natidof 8 \u1edf n\u01a1i c\u00f3 \u0111\u1ed9 \u1ea9m kh\u00f4ng qu\u00e1 70%, nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, n\u01a1i kh\u00f4 r\u00e1o, s\u1ea1ch s\u1ebd. \u0110\u1ec3 tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Natidof 8 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/coltramyl-4mg\/\">Coltramyl 4mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh Thiocolchicosid 4mg, s\u1ea3n xu\u1ea5t b\u1edfi Chi nh\u00e1nh Resantis Vi\u1ec7t Nam \u2013 C\u00f4ng ty TNHH m\u1ed9t th\u00e0nh vi\u00ean D\u01b0\u1ee3c S\u00e0i G\u00f2n, \u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110918424 (S\u0110K c\u0169: VD-22638-15), h\u1ed7 tr\u1ee3 l\u00e0m gi\u1ea3m co th\u1eaft c\u01a1 g\u00e2y \u0111au trong b\u1ec7nh c\u01a1 x\u01b0\u01a1ng kh\u1edbp<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/mezacosid-4mg\/\">Mezacosid<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh Thiocolchicosid 4mg, s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m D\u01b0\u1ee3c H\u00e0 T\u00e2y \u2013 Vi\u1ec7t Nam, gi\u1ea3m \u0111\u00e1ng k\u1ec3 s\u1ef1 co th\u1eaft c\u00f3 ngu\u1ed3n g\u1ed1c trung \u01b0\u01a1ng.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Natidof 8 do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/HDSD-Natidof-8-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a><\/li>\n<li>Karmakar A, Jaiswal A, Mandal S, Khan AA, Mitra M. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40838227\/\" rel=\"noopener\">Therapeutic efficacy of thiocolchicoside-nonsteroidal anti-inflammatory drug combination in pain management: A systematic review and cross-sectional real-world study<\/a>, truy c\u1eadp ng\u00e0y 17 th\u00e1ng 10 n\u0103m 2025<\/li>\n<li>Reuter S, Prasad S, Phromnoi K, Ravindran J, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20978115\/\" rel=\"noopener\">Thiocolchicoside exhibits anticancer effects through downregulation of NF-\u03baB pathway and its regulated gene products linked to inflammation and cancer<\/a>, truy c\u1eadp ng\u00e0y 17 th\u00e1ng 10 n\u0103m 2025<\/li>\n<li>Artusi M, Santi P, Colombo P, Junginger HE. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12480286\/\" rel=\"noopener\">Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies<\/a>, truy c\u1eadp ng\u00e0y 17 th\u00e1ng 10 n\u0103m 2025<\/li>\n<li>PLOTKA C, JEQUIER R. Le thiocolchicoside, \u00e9tude pharmacologique <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13425730\/\" rel=\"noopener\">[Thiocolchicoside, pharmacological study],<\/a> truy c\u1eadp ng\u00e0y 17 th\u00e1ng 10 n\u0103m 2025<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Natidof 8 \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng tho\u00e1i h\u00f3a \u0111\u1ed1t s\u1ed1ng, r\u1ed1i lo\u1ea1n t\u01b0 th\u1ebf c\u1ed9t s\u1ed1ng (\u0111au th\u1eaft l\u01b0ng, \u0111au l\u01b0ng, v\u1eb9o c\u1ed5), s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n S.P.M, s\u1ed1 \u0111\u0103ng k\u00fd 893110046000<\/p>\n","protected":false},"author":1,"featured_media":145224,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-144697","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/144697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=144697"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/145224"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=144697"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=144697"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=144697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}