{"id":144340,"date":"2025-10-11T12:53:07","date_gmt":"2025-10-11T05:53:07","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=144340"},"modified":"2025-10-11T12:55:29","modified_gmt":"2025-10-11T05:55:29","slug":"fientalf-60mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/fientalf-60mg\/","title":{"rendered":"Fientalf 60mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Fientalf 60mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH DRP Inter c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110226723<\/strong><\/p>\n<h2>Fientalf 60mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i<strong> vi\u00ean u\u1ed1ng Fientalf 60mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Edoxaban \u2026&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.60mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110226723<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Fientalf 60mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Edoxaban l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc, tr\u1ef1c ti\u1ebfp v\u00e0 c\u00f3 h\u1ed3i ph\u1ee5c \u0111\u1ed1i v\u1edbi y\u1ebfu t\u1ed1 Xa, m\u1ed9t enzyme then ch\u1ed1t trong qu\u00e1 tr\u00ecnh \u0111\u00f4ng m\u00e1u. Vi\u1ec7c \u1ee9c ch\u1ebf y\u1ebfu t\u1ed1 Xa gi\u00fap l\u00e0m gi\u1ea3m s\u1ea3n xu\u1ea5t thrombin, k\u00e9o d\u00e0i th\u1eddi gian t\u1ea1o c\u1ee5c m\u00e1u \u0111\u00f4ng v\u00e0 ng\u0103n h\u00ecnh th\u00e0nh huy\u1ebft kh\u1ed1i m\u1edbi. Nh\u1edd \u0111\u00f3, Fientalf 60mg gi\u00fap gi\u1ea3m nguy c\u01a1 \u0111\u1ed9t qu\u1ef5 v\u00e0 bi\u1ebfn ch\u1ee9ng do t\u1eafc m\u1ea1ch.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Sau khi u\u1ed1ng, Edoxaban \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 1\u20132 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 62%, c\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n.<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c c\u00f3 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 trung b\u00ecnh kho\u1ea3ng 107L, g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 55%. N\u1ed3ng \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 3 ng\u00e0y d\u00f9ng li\u00ean ti\u1ebfp.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Edoxaban ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c th\u1ee7y ph\u00e2n b\u1edfi enzyme carboxylesterase 1 v\u00e0 m\u1ed9t ph\u1ea7n nh\u1ecf chuy\u1ec3n h\u00f3a qua CYP3A4\/5 (&lt;10%). C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh chi\u1ebfm t\u1ef7 l\u1ec7 th\u1ea5p, trong \u0111\u00f3 M-4 l\u00e0 ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh \u0111\u00e1ng k\u1ec3 nh\u1ea5t.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Kho\u1ea3ng 35% thu\u1ed1c \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua th\u1eadn, ph\u1ea7n c\u00f2n l\u1ea1i qua m\u1eadt v\u00e0 ph\u00e2n. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh 10\u201314 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Fientalf 60mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Ph\u00f2ng ng\u1eeba \u0111\u1ed9t qu\u1ef5 v\u00e0 thuy\u00ean t\u1eafc m\u1ea1ch h\u1ec7 th\u1ed1ng \u1edf ng\u01b0\u1eddi l\u1edbn b\u1ecb rung nh\u0129 kh\u00f4ng do van tim (NVAF) c\u00f3 \u00edt nh\u1ea5t m\u1ed9t y\u1ebfu t\u1ed1 nguy c\u01a1 nh\u01b0: suy tim sung huy\u1ebft, t\u0103ng huy\u1ebft \u00e1p, tu\u1ed5i \u2265 75, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, ti\u1ec1n s\u1eed \u0111\u1ed9t qu\u1ef5 ho\u1eb7c c\u01a1n thi\u1ebfu m\u00e1u n\u00e3o tho\u00e1ng qua (TIA).<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng t\u00e1i ph\u00e1t huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT) v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i (PE) sau khi \u0111\u00e3 d\u00f9ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1eddng ti\u00eam t\u1ed1i thi\u1ec3u 5 ng\u00e0y.<\/p>\n<figure id=\"attachment_144341\" aria-describedby=\"caption-attachment-144341\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-144341 size-full\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Fientalf-60mg.jpg\" alt=\"Fientalf 60mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Fientalf-60mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Fientalf-60mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Fientalf-60mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Fientalf-60mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Fientalf-60mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-144341\" class=\"wp-caption-text\">Thu\u1ed1c Fientalf 60mg c\u00f3 t\u00e1c d\u1ee5ng ng\u0103n ng\u1eeba h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Ph\u00f2ng ng\u1eeba \u0111\u1ed9t qu\u1ef5 v\u00e0 thuy\u00ean t\u1eafc m\u1ea1ch h\u1ec7 th\u1ed1ng: U\u1ed1ng ng\u00e0y d\u00f9ng 60mg Edoxaban ~ 1 vi\u00ean <span style=\"font-size: 14.4px;\">Fientalf 60mg<\/span><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i: ng\u00e0y d\u00f9ng 60mg Edoxaban ~ 1 vi\u00ean <span style=\"font-size: 14.4px;\">Fientalf 60mg,<\/span> sau khi \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u \u0111\u01b0\u1eddng ti\u00eam \u00edt nh\u1ea5t 5 ng\u00e0y.<\/p>\n<p>Gi\u1ea3m li\u1ec1u c\u00f2n ng\u00e0y d\u00f9ng 30mg Edoxaban ~ 1 n\u1eeda vi\u00ean <span style=\"font-size: 14.4px;\">Fientalf 60mg<\/span> trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn trung b\u00ecnh \u0111\u1ebfn n\u1eb7ng (CrCL 15\u201350 mL\/ph\u00fat).<\/li>\n<li>C\u00e2n n\u1eb7ng \u2264 60 kg.<\/li>\n<li>D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf P-glycoprotein nh\u01b0 ciclosporin, dronedaron, erythromycin ho\u1eb7c ketoconazol.<\/li>\n<\/ul>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb: T\u1ed1i thi\u1ec3u 3 th\u00e1ng, \u0111i\u1ec1u ch\u1ec9nh t\u00f9y v\u00e0o nguy c\u01a1 huy\u1ebft kh\u1ed1i ho\u1eb7c ch\u1ea3y m\u00e1u c\u1ee7a t\u1eebng b\u1ec7nh nh\u00e2n.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng nguy\u00ean <strong>vi\u00ean n\u00e9n Fientalf 60mg<\/strong> v\u1edbi n\u01b0\u1edbc, c\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Fientalf 60mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Qu\u00e1 m\u1eabn v\u1edbi Edoxaban ho\u1eb7c t\u00e1 d\u01b0\u1ee3c c\u00f3 trong Fientalf 60mg<\/p>\n<p>\u0110ang b\u1ecb ch\u1ea3y m\u00e1u nghi\u00eam tr\u1ecdng tr\u00ean l\u00e2m s\u00e0ng.<\/p>\n<p>B\u1ec7nh gan c\u00f3 r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u v\u00e0 t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/p>\n<p>C\u00f3 t\u1ed5n th\u01b0\u01a1ng ho\u1eb7c nguy c\u01a1 xu\u1ea5t huy\u1ebft l\u1edbn (nh\u01b0 lo\u00e9t ti\u00eau h\u00f3a, kh\u1ed1i u \u00e1c t\u00ednh c\u00f3 ch\u1ea3y m\u00e1u, ph\u1eabu thu\u1eadt ho\u1eb7c ch\u1ea5n th\u01b0\u01a1ng g\u1ea7n \u0111\u00e2y, xu\u1ea5t huy\u1ebft n\u1ed9i s\u1ecd, gi\u00e3n t\u0129nh m\u1ea1ch th\u1ef1c qu\u1ea3n, ph\u00ecnh m\u1ea1ch, d\u1ecb d\u1ea1ng m\u1ea1ch m\u00e1u n\u00e3o).<\/p>\n<p>T\u0103ng huy\u1ebft \u00e1p n\u1eb7ng kh\u00f4ng ki\u1ec3m so\u00e1t.<\/p>\n<p>\u0110ang d\u00f9ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng kh\u00e1c (heparin, warfarin, dabigatran, rivaroxaban, apixaban&#8230;) tr\u1eeb khi \u0111ang chuy\u1ec3n \u0111\u1ed5i \u0111i\u1ec1u tr\u1ecb theo h\u01b0\u1edbng d\u1eabn b\u00e1c s\u0129.<\/p>\n<p>Ph\u1ee5 n\u1eef mang thai<\/p>\n<p>M\u1eb9 cho con b\u00fa.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Nguy c\u01a1 ch\u1ea3y m\u00e1u: Edoxaban c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n cao tu\u1ed5i, suy th\u1eadn, r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u ho\u1eb7c \u0111ang d\u00f9ng thu\u1ed1c kh\u00e1c c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean ti\u1ec3u c\u1ea7u ho\u1eb7c \u0111\u00f4ng m\u00e1u.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy th\u1eadn: C\u1ea7n gi\u1ea3m li\u1ec1u theo m\u1ee9c thanh th\u1ea3i creatinin. Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng cho b\u1ec7nh nh\u00e2n suy th\u1eadn giai \u0111o\u1ea1n cu\u1ed1i ho\u1eb7c \u0111ang l\u1ecdc m\u00e1u.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan: Kh\u00f4ng d\u00f9ng \u1edf ng\u01b0\u1eddi b\u1ecb suy gan n\u1eb7ng. N\u00ean ki\u1ec3m tra men gan tr\u01b0\u1edbc v\u00e0 trong khi \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Ng\u1eebng thu\u1ed1c tr\u01b0\u1edbc ph\u1eabu thu\u1eadt: D\u1eebng thu\u1ed1c \u00edt nh\u1ea5t 24 gi\u1edd tr\u01b0\u1edbc khi ph\u1eabu thu\u1eadt ho\u1eb7c th\u1ee7 thu\u1eadt c\u00f3 nguy c\u01a1 ch\u1ea3y m\u00e1u. D\u00f9ng l\u1ea1i sau khi \u0111\u00e3 c\u1ea7m m\u00e1u ho\u00e0n to\u00e0n.<\/p>\n<p>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c: Th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p v\u1edbi aspirin, NSAID, thu\u1ed1c \u1ee9c ch\u1ebf ti\u1ec3u c\u1ea7u P2Y12, SSRI, SNRI ho\u1eb7c c\u00e1c thu\u1ed1c ti\u00eau s\u1ee3i huy\u1ebft.<\/p>\n<p>B\u1ec7nh nh\u00e2n ung th\u01b0 ho\u1eb7c h\u1ed9i ch\u1ee9ng kh\u00e1ng phospholipid: Hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 an to\u00e0n ch\u01b0a \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp r\u00f5, kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng.<\/p>\n<p>Theo d\u00f5i x\u00e9t nghi\u1ec7m: M\u1eb7c d\u00f9 kh\u00f4ng c\u1ea7n theo d\u00f5i \u0111\u1ecbnh k\u1ef3, nh\u01b0ng trong tr\u01b0\u1eddng h\u1ee3p \u0111\u1eb7c bi\u1ec7t (ph\u1eabu thu\u1eadt c\u1ea5p c\u1ee9u, nghi qu\u00e1 li\u1ec1u), c\u00f3 th\u1ec3 \u0111\u1ecbnh l\u01b0\u1ee3ng ho\u1ea1t t\u00ednh y\u1ebfu t\u1ed1 Xa \u0111\u1ec3 h\u1ed7 tr\u1ee3 x\u1eed tr\u00ed.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Trong qu\u00e1 tr\u00ecnh nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng v\u00e0 s\u1eed d\u1ee5ng sau khi l\u01b0u h\u00e0nh, Fientalf c\u00f3 th\u1ec3 g\u00e2y ra nhi\u1ec1u ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i li\u00ean quan \u0111\u1ebfn t\u00e1c d\u1ee5ng ch\u1ed1ng \u0111\u00f4ng m\u00e1u. T\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p nh\u1ea5t l\u00e0 ch\u1ea3y m\u00e1u (chi\u1ebfm kho\u1ea3ng 7\u20138%), c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n \u1edf b\u1ea5t k\u1ef3 v\u1ecb tr\u00ed n\u00e0o tr\u00ean c\u01a1 th\u1ec3 v\u00e0 trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p nghi\u00eam tr\u1ecdng c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u1eed vong.<\/p>\n<p>C\u00e1c bi\u1ec3u hi\u1ec7n th\u01b0\u1eddng \u0111\u01b0\u1ee3c ghi nh\u1eadn g\u1ed3m: ti\u1ec3u ra m\u00e1u, xu\u1ea5t huy\u1ebft \u00e2m \u0111\u1ea1o, xu\u1ea5t huy\u1ebft da ho\u1eb7c m\u00f4 m\u1ec1m, ch\u1ea3y m\u00e1u t\u1ea1i v\u1ecb tr\u00ed ti\u00eam ho\u1eb7c ph\u1eabu thu\u1eadt, ph\u00e1t ban, n\u1ed5i m\u1ec1 \u0111ay, \u0111au c\u01a1 do xu\u1ea5t huy\u1ebft trong c\u01a1, thi\u1ebfu m\u00e1u sau xu\u1ea5t huy\u1ebft v\u00e0 c\u00e1c r\u1ed1i lo\u1ea1n v\u1ec1 ch\u1ee9c n\u0103ng gan. M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm g\u1eb7p c\u00f3 th\u1ec3 b\u1ecb xu\u1ea5t huy\u1ebft trong kh\u1edbp, d\u01b0\u1edbi m\u00e0ng c\u1ee9ng ho\u1eb7c t\u1ea1i v\u00f9ng m\u1ed5.<\/p>\n<p>Nguy c\u01a1 ch\u1ea3y m\u00e1u cao h\u01a1n \u1edf ng\u01b0\u1eddi b\u1ecb t\u0103ng huy\u1ebft \u00e1p kh\u00f4ng ki\u1ec3m so\u00e1t, ph\u1ee5 n\u1eef c\u00f3 kinh nguy\u1ec7t nhi\u1ec1u ho\u1eb7c k\u00e9o d\u00e0i, ho\u1eb7c \u0111ang d\u00f9ng \u0111\u1ed3ng th\u1eddi thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh \u0111\u00f4ng m\u00e1u. D\u1ea5u hi\u1ec7u c\u1ea3nh b\u00e1o bao g\u1ed3m: da t\u00e1i, ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, \u0111au \u0111\u1ea7u, kh\u00f3 th\u1edf, s\u01b0ng n\u1ec1 b\u1ea5t th\u01b0\u1eddng ho\u1eb7c bi\u1ec3u hi\u1ec7n s\u1ed1c do m\u1ea5t m\u00e1u. Trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i huy\u1ebft h\u1ecdc \u0111\u1ec3 ph\u00e1t hi\u1ec7n s\u1edbm t\u00ecnh tr\u1ea1ng thi\u1ebfu m\u00e1u ho\u1eb7c ch\u1ea3y m\u00e1u ti\u1ec1m \u1ea9n.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Fientalf (edoxaban) \u0111\u01b0\u1ee3c h\u1ea5p thu ch\u1ee7 y\u1ebfu t\u1ea1i ph\u1ea7n tr\u00ean c\u1ee7a \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, do \u0111\u00f3 c\u00e1c y\u1ebfu t\u1ed1 l\u00e0m t\u0103ng t\u1ed1c \u0111\u1ed9 l\u00e0m r\u1ed7ng d\u1ea1 d\u00e0y ho\u1eb7c t\u0103ng nhu \u0111\u1ed9ng ru\u1ed9t c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u1ea5p thu c\u1ee7a thu\u1ed1c.<\/p>\n<p>Thu\u1ed1c l\u00e0 c\u01a1 ch\u1ea5t c\u1ee7a P-gp, v\u00ec v\u1eady c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf P-gp nh\u01b0 ciclosporin, dronedarone, erythromycin ho\u1eb7c ketoconazole c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 edoxaban trong huy\u1ebft t\u01b0\u01a1ng. Khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c n\u00e0y, c\u1ea7n gi\u1ea3m li\u1ec1u Fientalf xu\u1ed1ng 30 mg\/ng\u00e0y. Trong khi \u0111\u00f3, vi\u1ec7c ph\u1ed1i h\u1ee3p v\u1edbi quinidin, verapamil ho\u1eb7c amiodaron kh\u00f4ng y\u00eau c\u1ea7u \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u, tuy c\u00f3 t\u0103ng nh\u1eb9 n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u nh\u01b0ng kh\u00f4ng c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng.<\/p>\n<p>Ng\u01b0\u1ee3c l\u1ea1i, c\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng P-gp nh\u01b0 rifampicin, phenytoin, carbamazepin, phenobarbital hay St. John\u2019s Wort c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 edoxaban v\u00e0 hi\u1ec7u l\u1ef1c ch\u1ed1ng \u0111\u00f4ng, n\u00ean c\u1ea7n th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p.<\/p>\n<p>Khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi digoxin, n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a c\u1ee7a edoxaban c\u00f3 th\u1ec3 t\u0103ng nh\u1eb9 (~17%) nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn m\u1ee9c \u0111\u1ed9 h\u1ea5p thu ho\u1eb7c th\u1ea3i tr\u1eeb, v\u00ec v\u1eady kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u.<\/p>\n<p>Tr\u00e1nh ph\u1ed1i h\u1ee3p Fientalf v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng kh\u00e1c, do l\u00e0m t\u0103ng m\u1ea1nh nguy c\u01a1 ch\u1ea3y m\u00e1u. Khi s\u1eed d\u1ee5ng c\u00f9ng acid acetylsalicylic (ASA) \u1edf li\u1ec1u cao (tr\u00ean 100 mg\/ng\u00e0y), th\u1eddi gian ch\u1ea3y m\u00e1u v\u00e0 n\u1ed3ng \u0111\u1ed9 edoxaban trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ec1u t\u0103ng \u0111\u00e1ng k\u1ec3, n\u00ean ch\u1ec9 \u0111\u01b0\u1ee3c ph\u1ed1i h\u1ee3p trong tr\u01b0\u1eddng h\u1ee3p th\u1eadt c\u1ea7n thi\u1ebft v\u00e0 d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t y t\u1ebf. D\u00f9ng li\u1ec1u th\u1ea5p ASA (\u2264100 mg\/ng\u00e0y) \u0111\u01b0\u1ee3c xem l\u00e0 an to\u00e0n.<\/p>\n<p>Khi k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u nh\u01b0 clopidogrel ho\u1eb7c nh\u00f3m thienopyridine, nguy c\u01a1 ch\u1ea3y m\u00e1u t\u0103ng l\u00ean nh\u01b0ng v\u1eabn th\u1ea5p h\u01a1n so v\u1edbi warfarin. Kinh nghi\u1ec7m l\u00e2m s\u00e0ng khi ph\u1ed1i h\u1ee3p k\u00e9p thu\u1ed1c ch\u1ed1ng k\u1ebft t\u1eadp ho\u1eb7c d\u00f9ng c\u00f9ng thu\u1ed1c ti\u00eau s\u1ee3i huy\u1ebft c\u00f2n h\u1ea1n ch\u1ebf.<\/p>\n<p>Ngo\u00e0i ra, vi\u1ec7c ph\u1ed1i h\u1ee3p Fientalf v\u1edbi NSAID (nh\u01b0 naproxen) ho\u1eb7c thu\u1ed1c \u1ee9c ch\u1ebf t\u00e1i thu h\u1ed3i serotonin\/serotonin-norepinephrine (SSRIs\/SNRIs) c\u00f3 th\u1ec3 l\u00e0m k\u00e9o d\u00e0i th\u1eddi gian ch\u1ea3y m\u00e1u, n\u00ean kh\u00f4ng n\u00ean d\u00f9ng l\u00e2u d\u00e0i.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 kh\u1ea3 n\u0103ng mang thai: N\u00ean tr\u00e1nh mang thai trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fientalf.<\/p>\n<p>Ph\u1ee5 n\u1eef mang thai: Thu\u1ed1c c\u00f3 th\u1ec3 \u0111i qua h\u00e0ng r\u00e0o nhau thai v\u00e0 g\u00e2y \u0111\u1ed9c t\u00ednh tr\u00ean ph\u00f4i, l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u \u1edf m\u1eb9 v\u00e0 thai nhi. Do \u0111\u00f3, ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Fientalf trong thai k\u1ef3.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: C\u00e1c nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt cho th\u1ea5y edoxaban b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9, v\u00ec v\u1eady kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c trong giai \u0111o\u1ea1n cho con b\u00fa. N\u1ebfu c\u1ea7n \u0111i\u1ec1u tr\u1ecb, ph\u1ea3i quy\u1ebft \u0111\u1ecbnh gi\u1eefa vi\u1ec7c ng\u1eebng thu\u1ed1c ho\u1eb7c ng\u1eebng cho b\u00fa.<\/p>\n<p>Kh\u1ea3 n\u0103ng sinh s\u1ea3n: Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u c\u1ee5 th\u1ec3 tr\u00ean ng\u01b0\u1eddi. Th\u1eed nghi\u1ec7m tr\u00ean chu\u1ed9t kh\u00f4ng ghi nh\u1eadn \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng sinh s\u1ea3n \u1edf c\u1ea3 con \u0111\u1ef1c v\u00e0 c\u00e1i.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Fientalf kh\u00f4ng \u1ea3nh h\u01b0\u1edfng ho\u1eb7c \u1ea3nh h\u01b0\u1edfng kh\u00f4ng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe, thao t\u00e1c m\u00e1y m\u00f3c ho\u1eb7c c\u00e1c ho\u1ea1t \u0111\u1ed9ng c\u1ea7n s\u1ef1 t\u1eadp trung cao. Tuy nhi\u00ean, n\u1ebfu c\u00f3 tri\u1ec7u ch\u1ee9ng nh\u01b0 ch\u00f3ng m\u1eb7t ho\u1eb7c m\u1ec7t do thi\u1ebfu m\u00e1u, c\u1ea7n tr\u00e1nh c\u00e1c c\u00f4ng vi\u1ec7c \u0111\u00f2i h\u1ecfi s\u1ef1 t\u1ec9nh t\u00e1o.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>D\u00f9ng qu\u00e1 li\u1ec1u Fientalf c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u00ecnh tr\u1ea1ng xu\u1ea5t huy\u1ebft nghi\u00eam tr\u1ecdng. Kinh nghi\u1ec7m l\u00e2m s\u00e0ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p n\u00e0y c\u00f2n h\u1ea1n ch\u1ebf v\u00e0 hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho edoxaban.<\/p>\n<p>Khi nghi ng\u1edd qu\u00e1 li\u1ec1u, c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc d\u00f9ng than ho\u1ea1t \u0111\u1ec3 gi\u1ea3m h\u1ea5p thu thu\u1ed1c trong \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Bi\u1ec7n ph\u00e1p n\u00e0y \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb d\u1ef1a tr\u00ean c\u01a1 ch\u1ebf chung c\u1ee7a c\u00e1c thu\u1ed1c c\u00f9ng nh\u00f3m, d\u00f9 ch\u01b0a c\u00f3 d\u1eef li\u1ec7u c\u1ee5 th\u1ec3 cho edoxaban. Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd v\u1ec1 d\u1ea5u hi\u1ec7u ch\u1ea3y m\u00e1u v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 t\u00f9y theo tri\u1ec7u ch\u1ee9ng.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Fientalf 60mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Fientalf 60mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Fientalf 60mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>Thu\u1ed1c Fientalf 60mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Fientalf 60mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/lixiana-60mg\/\">Lixiana 60mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Edoxaban h\u00e0m l\u01b0\u1ee3ng 60mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Daiichi Sankyo Europe GmbH, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb thuy\u00ean t\u1eafc m\u1ea1ch v\u00e0 ng\u1eeba \u0111\u1ed9t qu\u1ef5<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/lixiana-30mg\/\">Lixiana 30mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Edoxaban h\u00e0m l\u01b0\u1ee3ng 30mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Daiichi Sankyo Europe GmbH, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb thuy\u00ean t\u1eafc m\u1ea1ch v\u00e0 ng\u1eeba \u0111\u1ed9t qu\u1ef5<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Stacy ZA, Call WB, Hartmann AP, Peters GL, Richter SK (2016). Edoxaban: A Comprehensive Review of the Pharmacology and Clinical Data for the Management of Atrial Fibrillation and Venous Thromboembolism. Cardiol Ther. Truy c\u1eadp ng\u00e0y 11 th\u00e1ng 10 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4906085\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4906085\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Fientalf 60mg c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc y\u1ebfu t\u1ed1 Xa trong chu\u1ed7i ph\u1ea3n \u1ee9ng \u0111\u00f4ng m\u00e1u, ng\u0103n ng\u1eeba h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng, t\u1eeb \u0111\u00f3 gi\u1ea3m nguy c\u01a1 \u0111\u1ed9t qu\u1ef5, thuy\u00ean t\u1eafc m\u1ea1ch<\/p>\n","protected":false},"author":1,"featured_media":144342,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-144340","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/144340","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=144340"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/144342"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=144340"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=144340"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=144340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}